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Gene: FLT3LG (fms related receptor tyrosine kinase 3 ligand) Homo sapiens
Analyze
Symbol:
FLT3LG
Name:
fms related receptor tyrosine kinase 3 ligand
RGD ID:
1353824
HGNC Page
HGNC:3766
Description:
Predicted to enable identical protein binding activity and receptor tyrosine kinase binding activity. Involved in hemopoiesis and positive regulation of cell population proliferation. Predicted to be located in external side of plasma membrane. Predicted to be active in cell surface and extracellular space. Implicated in colon carcinoma; glioblastoma; high grade glioma; and immunodeficiency 125. Biomarker of Fanconi anemia; aplastic anemia; multiple myeloma; and myelofibrosis.
Type:
protein-coding
RefSeq Status:
VALIDATED
Previously known as:
FL; FLG3L; flt3 ligand; FLT3L; fms related tyrosine kinase 3 ligand; fms-related tyrosine kinase 3 ligand; IMD125; SL cytokine
RGD Orthologs
Alliance Orthologs
More Info
more info ...
More Info
Species
Gene symbol and name
Data Source
Assertion derived from
less info ...
Orthologs 1
Mus musculus (house mouse):
Flt3l (FMS-like tyrosine kinase 3 ligand) HGNC
EggNOG, Ensembl, HGNC, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther, PhylomeDB, Treefam
Rattus norvegicus (Norway rat):
Flt3lg (Fms related receptor tyrosine kinase 3 ligand) HGNC
Ensembl, NCBI
Chinchilla lanigera (long-tailed chinchilla):
Flt3lg (fms related receptor tyrosine kinase 3 ligand) NCBI
Ortholog
Pan paniscus (bonobo/pygmy chimpanzee):
FLT3LG (fms related receptor tyrosine kinase 3 ligand) NCBI
Ortholog
Canis lupus familiaris (dog):
FLT3LG (fms related receptor tyrosine kinase 3 ligand) HGNC
EggNOG, Ensembl, HomoloGene, Inparanoid, NCBI, OMA, OrthoDB, Panther, Treefam
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):
Flt3lg (fms related receptor tyrosine kinase 3 ligand) NCBI
Ortholog
Chlorocebus sabaeus (green monkey):
FLT3LG (fms related receptor tyrosine kinase 3 ligand) NCBI
Ortholog
Heterocephalus glaber (naked mole-rat):
Flt3lg (fms related receptor tyrosine kinase 3 ligand) NCBI
Ortholog
Rattus rattus (black rat):
Flt3lg (fms related receptor tyrosine kinase 3 ligand) NCBI
Ortholog
Other homologs 2
Rattus norvegicus (Norway rat):
Rpl13a (ribosomal protein L13A) HGNC
Inparanoid
Rattus norvegicus (Norway rat):
Rxylt1 (ribitol xylosyltransferase 1) HGNC
OMA
Alliance orthologs 3
Mus musculus (house mouse):
Flt3l (FMS-like tyrosine kinase 3 ligand)
Alliance
DIOPT (Ensembl Compara|HGNC|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Rattus norvegicus (Norway rat):
Flt3lg (Fms related receptor tyrosine kinase 3 ligand)
Alliance
DIOPT (Ensembl Compara|HGNC|Hieranoid|InParanoid|OMA|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Rattus norvegicus (Norway rat):
Flt3lg (Fms related receptor tyrosine kinase 3 ligand)
Alliance
DIOPT (HGNC)
Xenopus laevis (African clawed frog):
flt3lg.S
Alliance
DIOPT (Xenbase)
Xenopus laevis (African clawed frog):
flt3lg.L
Alliance
DIOPT (Xenbase)
Xenopus tropicalis (tropical clawed frog):
flt3lg
Alliance
DIOPT (Hieranoid|InParanoid|OrthoFinder|OrthoInspector|PANTHER|PhylomeDB|SonicParanoid)
Allele / Splice:
See ClinVar data
Latest Assembly:
GRCh38 - Human Genome Assembly GRCh38
Position:
Human Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCh38 19 49,474,215 - 49,486,231 (+) NCBI GRCh38 GRCh38 hg38 GRCh38 GRCh38.p14 Ensembl 19 49,474,150 - 49,486,233 (+) Ensembl hg38 GRCh38 GRCh37 19 49,977,472 - 49,989,488 (+) NCBI GRCh37 GRCh37 hg19 GRCh37 Build 36 19 54,669,298 - 54,681,300 (+) NCBI Build 36 Build 36 hg18 NCBI36 Build 34 19 54,669,297 - 54,681,299 NCBI Celera 19 46,846,847 - 46,858,811 (+) NCBI Celera Cytogenetic Map 19 q13.33 NCBI HuRef 19 46,355,067 - 46,367,027 (+) NCBI HuRef CHM1_1 19 49,978,739 - 49,990,762 (+) NCBI CHM1_1 T2T-CHM13v2.0 19 52,474,188 - 52,486,197 (+) NCBI T2T-CHM13v2.0
JBrowse:
Imported Disease Annotations - ClinVar
Imported Disease Annotations - OMIM
Only show annotations with direct experimental evidence (0 objects hidden)
FLT3LG Human (+)-catechin decreases expression EXP 6480464 Catechin results in decreased expression of FLT3LG mRNA CTD PMID:15465739 FLT3LG Human 1,2-dichloroethane increases expression ISO Flt3l (Mus musculus) 6480464 ethylene dichloride results in increased expression of FLT3L mRNA CTD PMID:28960355 FLT3LG Human 1,2-dimethylhydrazine increases expression ISO Flt3l (Mus musculus) 6480464 1,2-Dimethylhydrazine results in increased expression of FLT3L mRNA CTD PMID:22206623 FLT3LG Human 1,2-dimethylhydrazine multiple interactions ISO Flt3l (Mus musculus) 6480464 [1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of FLT3L mRNA CTD PMID:22206623 FLT3LG Human 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of FLT3LG mRNA CTD PMID:21296121 FLT3LG Human 3,4-methylenedioxymethamphetamine increases expression ISO Flt3l (Mus musculus) 6480464 N-Methyl-3,4-methylenedioxyamphetamine results in increased expression of FLT3L mRNA CTD PMID:26251327 FLT3LG Human 4,4'-sulfonyldiphenol increases expression ISO Flt3l (Mus musculus) 6480464 bisphenol S results in increased expression of FLT3L mRNA CTD PMID:39298647 FLT3LG Human acrolein increases expression ISO Flt3l (Mus musculus) 6480464 Acrolein results in increased expression of FLT3L mRNA CTD PMID:18515264 FLT3LG Human antirheumatic drug decreases expression EXP 6480464 Antirheumatic Agents results in decreased expression of FLT3LG mRNA CTD PMID:24449571 FLT3LG Human benzo[a]pyrene affects methylation EXP 6480464 Benzo(a)pyrene affects the methylation of FLT3LG promoter CTD PMID:27901495 FLT3LG Human bisphenol A decreases expression ISO Flt3lg (Rattus norvegicus) 6480464 bisphenol A results in decreased expression of FLT3LG mRNA CTD PMID:25181051 FLT3LG Human bisphenol F decreases expression ISO Flt3l (Mus musculus) 6480464 bisphenol F results in decreased expression of FLT3L mRNA CTD PMID:38685157 FLT3LG Human cadmium dichloride multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of and results in increased more ... CTD PMID:26138014 FLT3LG Human cannabidiol decreases expression EXP 6480464 Cannabidiol results in decreased expression of FLT3LG mRNA CTD PMID:27932991 FLT3LG Human carbon nanotube decreases expression ISO Flt3l (Mus musculus) 6480464 Nanotubes, Carbon analog results in decreased expression of FLT3L mRNA; Nanotubes, Carbon results in decreased more ... CTD PMID:25554681|PMID:25620056 FLT3LG Human choline multiple interactions ISO Flt3l (Mus musculus) 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression more ... CTD PMID:20938992 FLT3LG Human cisplatin increases expression ISO Flt3l (Mus musculus) 6480464 Cisplatin results in increased expression of FLT3LG mRNA CTD PMID:21151649 FLT3LG Human cisplatin increases expression EXP 6480464 Cisplatin results in increased expression of FLT3LG mRNA CTD PMID:27392435 FLT3LG Human cisplatin multiple interactions EXP 6480464 [Cisplatin co-treated with jinfukang] results in increased expression of FLT3LG mRNA CTD PMID:27392435 FLT3LG Human crocidolite asbestos decreases expression ISO Flt3l (Mus musculus) 6480464 Asbestos, Crocidolite results in decreased expression of FLT3L mRNA CTD PMID:29279043 FLT3LG Human cyclophosphamide affects expression ISO Flt3l (Mus musculus) 6480464 Cyclophosphamide affects the expression of FLT3L mRNA CTD PMID:12624490 FLT3LG Human diazinon increases methylation EXP 6480464 Diazinon results in increased methylation of FLT3LG gene CTD PMID:22964155 FLT3LG Human diethylstilbestrol increases expression EXP 6480464 Diethylstilbestrol results in increased expression of FLT3LG mRNA CTD PMID:15766595 FLT3LG Human doxorubicin decreases expression ISO Flt3l (Mus musculus) 6480464 Doxorubicin results in decreased expression of FLT3L mRNA CTD PMID:39631538 FLT3LG Human ethyl methanesulfonate increases expression EXP 6480464 Ethyl Methanesulfonate results in increased expression of FLT3LG mRNA CTD PMID:23649840 FLT3LG Human flavonoids decreases expression EXP 6480464 Flavonoids results in decreased expression of FLT3LG mRNA CTD PMID:15465739 FLT3LG Human folic acid multiple interactions ISO Flt3l (Mus musculus) 6480464 [1,2-Dimethylhydrazine co-treated with Folic Acid] results in increased expression of FLT3L mRNA; [Methionine deficiency co-treated more ... CTD PMID:20938992|PMID:22206623 FLT3LG Human folic acid increases expression ISO Flt3l (Mus musculus) 6480464 Folic Acid results in increased expression of FLT3L mRNA CTD PMID:25629700 FLT3LG Human genistein increases expression ISO Flt3l (Mus musculus) 6480464 Genistein results in increased expression of FLT3LG mRNA CTD PMID:22553218 FLT3LG Human isotretinoin increases expression EXP 6480464 Isotretinoin results in increased expression of FLT3LG mRNA CTD PMID:20436886 FLT3LG Human L-methionine multiple interactions ISO Flt3l (Mus musculus) 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression more ... CTD PMID:20938992 FLT3LG Human lipopolysaccharide increases secretion EXP 6480464 Lipopolysaccharides results in increased secretion of FLT3LG protein CTD PMID:32800949 FLT3LG Human methyl methanesulfonate increases expression EXP 6480464 Methyl Methanesulfonate results in increased expression of FLT3LG mRNA CTD PMID:23649840 FLT3LG Human N-acetyl-L-cysteine multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of and results in increased more ... CTD PMID:26138014 FLT3LG Human nickel atom increases expression EXP 6480464 Nickel results in increased expression of FLT3LG mRNA CTD PMID:24768652|PMID:25583101 FLT3LG Human nickel sulfate decreases expression ISO Flt3l (Mus musculus) 6480464 nickel sulfate results in decreased expression of FLT3L mRNA CTD PMID:16100012 FLT3LG Human Nor-9-carboxy-delta9-THC multiple interactions EXP 6480464 [Cannabinoids results in increased abundance of 11-nor-delta(9)-tetrahydrocannabinol-9-carboxylic acid] which affects the methylation of FLT3LG gene CTD PMID:30521419 FLT3LG Human ozone multiple interactions ISO Flt3l (Mus musculus) 6480464 [Air Pollutants results in increased abundance of Ozone] which results in decreased expression of FLT3L more ... CTD PMID:27106289 FLT3LG Human paracetamol affects expression ISO Flt3l (Mus musculus) 6480464 Acetaminophen affects the expression of FLT3L mRNA CTD PMID:17562736 FLT3LG Human perfluorohexanesulfonic acid decreases expression EXP 6480464 perfluorohexanesulfonic acid results in decreased expression of FLT3LG mRNA CTD PMID:25812627 FLT3LG Human perfluorononanoic acid decreases expression EXP 6480464 perfluoro-n-nonanoic acid results in decreased expression of FLT3LG mRNA CTD PMID:25812627 FLT3LG Human perfluorooctanoic acid decreases expression EXP 6480464 perfluorooctanoic acid results in decreased expression of FLT3LG mRNA CTD PMID:25812627 FLT3LG Human resveratrol multiple interactions EXP 6480464 [Plant Extracts co-treated with Resveratrol] results in decreased expression of FLT3LG mRNA; Resveratrol results in more ... CTD PMID:23557933|PMID:26160960 FLT3LG Human S-nitrosoglutathione increases expression EXP 6480464 S-Nitrosoglutathione results in increased expression of FLT3LG mRNA CTD PMID:38825487 FLT3LG Human silicon dioxide increases expression EXP 6480464 Silicon Dioxide analog results in increased expression of FLT3LG mRNA CTD PMID:25895662 FLT3LG Human sirolimus decreases activity ISO Flt3l (Mus musculus) 6480464 Sirolimus results in decreased activity of FLT3LG protein CTD PMID:12531798 FLT3LG Human StemRegenin 1 multiple interactions EXP 6480464 StemRegenin 1 results in increased activity of [KITL protein co-treated with THPO protein co-treated with more ... CTD PMID:26160960 FLT3LG Human tetrachloromethane decreases expression ISO Flt3l (Mus musculus) 6480464 Carbon Tetrachloride results in decreased expression of FLT3L mRNA CTD PMID:17484886 FLT3LG Human tetraphene increases expression ISO Flt3l (Mus musculus) 6480464 benz(a)anthracene results in increased expression of FLT3L mRNA CTD PMID:26377693 FLT3LG Human titanium dioxide affects expression ISO Flt3l (Mus musculus) 6480464 titanium dioxide affects the expression of FLT3L mRNA CTD PMID:35295148 FLT3LG Human valproic acid increases methylation EXP 6480464 Valproic Acid results in increased methylation of FLT3LG gene CTD PMID:29154799 FLT3LG Human wortmannin multiple interactions EXP 6480464 wortmannin inhibits the reaction [[IL3 protein co-treated with CSF2 protein co-treated with FLT3LG protein co-treated more ... CTD PMID:23001822
QTLs in Region (GRCh38)
628541174 GWAS2449403_H dickkopf-like protein 1 measurement QTL GWAS2449403 (human) 3e-18 dickkopf-like protein 1 measurement 19 49478276 49478277 Human 628541175 GWAS2449404_H dickkopf-like protein 1 measurement QTL GWAS2449404 (human) 1e-46 dickkopf-like protein 1 measurement 19 49482346 49482347 Human 616565059 GWAS1961642_H interleukin 12 measurement QTL GWAS1961642 (human) 7e-13 interleukin 12 measurement 19 49476141 49476142 Human 598049187 GWAS1768486_H body height QTL GWAS1768486 (human) 2e-46 body height 19 49476141 49476142 Human 628563185 GWAS2471414_H interleukin 12 measurement QTL GWAS2471414 (human) 7e-13 blood interleukin-12 amount (VT:0008616) 19 49476141 49476142 Human 407187789 GWAS836765_H mean corpuscular hemoglobin QTL GWAS836765 (human) 9e-09 mean corpuscular hemoglobin 19 49476532 49476533 Human 597534359 GWAS1630433_H body height QTL GWAS1630433 (human) 2e-46 body height 19 49476141 49476142 Human 617127875 GWAS2145374_H monocyte percentage of leukocytes QTL GWAS2145374 (human) 3e-15 monocyte percentage of leukocytes 19 49476141 49476142 Human 597449489 GWAS1545563_H serum non-albumin protein measurement QTL GWAS1545563 (human) 3e-13 serum non-albumin protein measurement 19 49476141 49476142 Human 407172309 GWAS821285_H monocyte percentage of leukocytes QTL GWAS821285 (human) 9e-15 monocyte percentage of leukocytes 19 49476141 49476142 Human 597998131 GWAS1717430_H serum albumin amount QTL GWAS1717430 (human) 3e-09 serum albumin amount 19 49476141 49476142 Human 617129937 GWAS2147436_H dickkopf-like protein 1 measurement QTL GWAS2147436 (human) 3e-18 dickkopf-like protein 1 measurement 19 49478276 49478277 Human 597610628 GWAS1667488_H monocyte count QTL GWAS1667488 (human) 2e-15 monocyte count 19 49476141 49476142 Human 597380865 GWAS1476939_H monocyte count QTL GWAS1476939 (human) 1e-23 monocyte quantity (VT:0000223) blood monocyte count (CMO:0000032) 19 49476141 49476142 Human 598091837 GWAS1811136_H erythrocyte volume QTL GWAS1811136 (human) 1e-09 erythrocyte volume 19 49476532 49476533 Human 628784231 GWAS2692460_H serum albumin amount QTL GWAS2692460 (human) 3e-09 serum albumin amount 19 49476141 49476142 Human 597424261 GWAS1520335_H serum albumin measurement QTL GWAS1520335 (human) 3e-09 serum albumin measurement 19 49476141 49476142 Human 628810084 GWAS2718313_H monocyte percentage of leukocytes QTL GWAS2718313 (human) 3e-15 monocyte quantity (VT:0000223) blood monocyte count to total leukocyte count ratio (CMO:0000374) 19 49476141 49476142 Human 616487454 GWAS1884037_H blood protein amount QTL GWAS1884037 (human) 1e-24 blood protein amount 19 49476141 49476142 Human 597380787 GWAS1476861_H monocyte percentage of leukocytes QTL GWAS1476861 (human) 9e-15 monocyte quantity (VT:0000223) blood monocyte count to total leukocyte count ratio (CMO:0000374) 19 49476141 49476142 Human 407069039 GWAS718015_H blood protein measurement QTL GWAS718015 (human) 1e-24 blood protein measurement 19 49476141 49476142 Human 407173362 GWAS822338_H serum albumin measurement QTL GWAS822338 (human) 3e-09 serum albumin measurement 19 49476141 49476142 Human 597263778 GWAS1359852_H mean corpuscular hemoglobin QTL GWAS1359852 (human) 9e-09 mean corpuscular hemoglobin 19 49476532 49476533 Human 628543177 GWAS2451406_H dickkopf-like protein 1 measurement QTL GWAS2451406 (human) 7e-14 dickkopf-like protein 1 measurement 19 49480094 49480095 Human 616520955 GWAS1917538_H monocyte percentage of leukocytes QTL GWAS1917538 (human) 3e-15 monocyte percentage of leukocytes 19 49476141 49476142 Human 628607795 GWAS2516024_H mean corpuscular hemoglobin QTL GWAS2516024 (human) 9e-09 erythrocyte hemoglobin amount (VT:0010953) mean corpuscular hemoglobin (CMO:0000290) 19 49476532 49476533 Human 597588569 GWAS1645429_H monocyte count QTL GWAS1645429 (human) 5e-12 monocyte count 19 49476141 49476142 Human 597581526 GWAS1638386_H monocyte count QTL GWAS1638386 (human) 3e-24 monocyte quantity (VT:0000223) blood monocyte count (CMO:0000032) 19 49476141 49476142 Human 407294479 GWAS943455_H monocyte count QTL GWAS943455 (human) 1e-20 monocyte count 19 49476141 49476142 Human 628558269 GWAS2466498_H level of interleukin-12 subunit beta in blood QTL GWAS2466498 (human) 6e-13 level of interleukin-12 subunit beta in blood 19 49476141 49476142 Human 628952881 GWAS2861110_H monocyte count QTL GWAS2861110 (human) 2e-15 monocyte quantity (VT:0000223) blood monocyte count (CMO:0000032) 19 49476141 49476142 Human 628998705 GWAS2906934_H body height QTL GWAS2906934 (human) 2e-46 body height 19 49476141 49476142 Human 616531955 GWAS1928538_H dickkopf-like protein 1 measurement QTL GWAS1928538 (human) 7e-14 dickkopf-like protein 1 measurement 19 49480094 49480095 Human 1559110 SCL22_H Serum cholesterol level QTL 22 (human) 3.59 0.000241 Lipid level LDL cholesterol 19 31907594 57907594 Human 407299093 GWAS948069_H monocyte count QTL GWAS948069 (human) 1e-23 monocyte count 19 49476141 49476142 Human 616372584 GWAS1852826_H obsolete_blood protein measurement QTL GWAS1852826 (human) 1e-24 obsolete_blood protein measurement 19 49476141 49476142 Human 407275408 GWAS924384_H mosaic loss of chromosome Y measurement QTL GWAS924384 (human) 1e-08 mosaic loss of chromosome Y measurement 19 49476532 49476533 Human 597160525 GWAS1256599_H mean corpuscular volume QTL GWAS1256599 (human) 1e-09 mean corpuscular volume 19 49476532 49476533 Human 1331657 COPD9_H Chronic obstructive pulmonary disease QTL 9 (human) 1.94 Chronic airflow obstruction post-bronchodilator FEV1 19 31021760 57021760 Human 628773031 GWAS2681260_H blood protein amount QTL GWAS2681260 (human) 1e-24 blood protein amount 19 49476141 49476142 Human 597380549 GWAS1476623_H monocyte count QTL GWAS1476623 (human) 1e-20 monocyte quantity (VT:0000223) blood monocyte count (CMO:0000032) 19 49476141 49476142 Human 616563614 GWAS1960197_H level of interleukin-12 subunit beta in blood QTL GWAS1960197 (human) 6e-13 level of interleukin-12 subunit beta in blood 19 49476141 49476142 Human 628775323 GWAS2683552_H level of serum globulin type protein QTL GWAS2683552 (human) 3e-13 level of serum globulin type protein 19 49476141 49476142 Human 597610495 GWAS1667355_H monocyte count QTL GWAS1667355 (human) 9e-12 monocyte count 19 49479811 49479812 Human 628956824 GWAS2865053_H monocyte count QTL GWAS2865053 (human) 9e-12 monocyte quantity (VT:0000223) blood monocyte count (CMO:0000032) 19 49479811 49479812 Human 628538640 GWAS2446869_H erythrocyte volume QTL GWAS2446869 (human) 1e-09 erythrocyte volume 19 49476532 49476533 Human 407310767 GWAS959743_H serum non-albumin protein measurement QTL GWAS959743 (human) 3e-13 serum non-albumin protein measurement 19 49476141 49476142 Human 597448822 GWAS1544896_H blood protein measurement QTL GWAS1544896 (human) 1e-24 blood protein measurement 19 49476141 49476142 Human 407266600 GWAS915576_H body height QTL GWAS915576 (human) 2e-46 body height 19 49476141 49476142 Human 597997142 GWAS1716441_H level of serum globulin type protein QTL GWAS1716441 (human) 3e-13 level of serum globulin type protein 19 49476141 49476142 Human 407192624 GWAS841600_H mean corpuscular volume QTL GWAS841600 (human) 1e-09 mean corpuscular volume 19 49476532 49476533 Human 597581414 GWAS1638274_H monocyte count QTL GWAS1638274 (human) 1e-15 monocyte quantity (VT:0000223) blood monocyte count (CMO:0000032) 19 49476141 49476142 Human 616532293 GWAS1928876_H dickkopf-like protein 1 measurement QTL GWAS1928876 (human) 1e-46 dickkopf-like protein 1 measurement 19 49482346 49482347 Human 617198386 GWAS2178826_H interleukin 12 measurement QTL GWAS2178826 (human) 7e-13 interleukin 12 measurement 19 49476141 49476142 Human 616532292 GWAS1928875_H dickkopf-like protein 1 measurement QTL GWAS1928875 (human) 3e-18 dickkopf-like protein 1 measurement 19 49478276 49478277 Human 628959488 GWAS2867717_H monocyte count QTL GWAS2867717 (human) 5e-12 monocyte quantity (VT:0000223) blood monocyte count (CMO:0000032) 19 49476141 49476142 Human
