Flt3lg (fms related receptor tyrosine kinase 3 ligand) - Rat Genome Database

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Gene: Flt3lg (fms related receptor tyrosine kinase 3 ligand) Chinchilla lanigera
Analyze
Symbol: Flt3lg
Name: fms related receptor tyrosine kinase 3 ligand (Ensembl:fms related tyrosine kinase 3 ligand)
RGD ID: 8707955
Description: ENCODES a protein that exhibits receptor tyrosine kinase binding (ortholog); INVOLVED IN embryonic hemopoiesis (ortholog); homeostasis of number of cells within a tissue (ortholog); lymphocyte differentiation (ortholog); ASSOCIATED WITH aplastic anemia (ortholog); colon carcinoma (ortholog); developmental and epileptic encephalopathy 12 (ortholog); FOUND IN cell surface (ortholog); external side of plasma membrane (ortholog); extracellular space (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: fms related tyrosine kinase 3 ligand; fms-related tyrosine kinase 3 ligand
RGD Orthologs
Human
Mouse
Rat
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: ChiLan1.0 - Chinchilla ChiLan1.0 Assembly
Position:
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555591,365,938 - 1,370,002 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555591,364,056 - 1,371,245 (-)NCBIChiLan1.0ChiLan1.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


References

References - curated
# Reference Title Reference Citation
1. Transitive Annotation Pipeline Automated assignment of GO, PW and RDO ISO annotations across species
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Flt3lg
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555591,365,938 - 1,370,002 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555591,364,056 - 1,371,245 (-)NCBIChiLan1.0ChiLan1.0
FLT3LG
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381949,474,215 - 49,486,231 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1949,474,207 - 49,486,231 (+)EnsemblGRCh38hg38GRCh38
GRCh371949,977,472 - 49,989,488 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361954,669,298 - 54,681,300 (+)NCBINCBI36Build 36hg18NCBI36
Build 341954,669,297 - 54,681,299NCBI
Celera1946,846,847 - 46,858,811 (+)NCBICelera
Cytogenetic Map19q13.33NCBI
HuRef1946,355,067 - 46,367,027 (+)NCBIHuRef
CHM1_11949,978,739 - 49,990,762 (+)NCBICHM1_1
T2T-CHM13v2.01952,474,188 - 52,486,197 (+)NCBIT2T-CHM13v2.0
Flt3l
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39744,780,607 - 44,785,914 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl744,779,212 - 44,785,856 (-)EnsemblGRCm39 Ensembl
GRCm38745,131,183 - 45,136,490 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl745,129,788 - 45,136,432 (-)EnsemblGRCm38mm10GRCm38
MGSCv37752,386,559 - 52,391,802 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36744,999,456 - 45,004,327 (-)NCBIMGSCv36mm8
Celera740,584,281 - 40,589,522 (-)NCBICelera
Cytogenetic Map7B3NCBI
cM Map729.14NCBI
Flt3lg
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81104,751,518 - 104,756,925 (-)NCBIGRCr8
mRatBN7.2195,615,056 - 95,620,463 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl195,609,370 - 95,620,463 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1101,000,447 - 101,005,854 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01109,473,114 - 109,478,521 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01102,763,521 - 102,768,928 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01101,126,006 - 101,131,413 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1101,124,479 - 101,131,413 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01102,190,086 - 102,197,519 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4195,607,131 - 95,611,290 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera189,873,472 - 89,878,870 (-)NCBICelera
Cytogenetic Map1q22NCBI
FLT3LG
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22055,589,080 - 55,601,931 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11957,509,418 - 57,522,277 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01946,486,169 - 46,499,008 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11955,410,448 - 55,422,545 (+)NCBIpanpan1.1PanPan1.1panPan2
FLT3LG
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11107,015,222 - 107,025,181 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1107,015,223 - 107,024,708 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1106,598,496 - 106,607,982 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01107,535,285 - 107,544,772 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1107,535,286 - 107,545,011 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11107,208,335 - 107,217,819 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01106,850,390 - 106,859,883 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01107,691,506 - 107,700,992 (-)NCBIUU_Cfam_GSD_1.0
Flt3lg
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934921,723,863 - 21,733,400 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366643,343,491 - 3,350,176 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366643,343,541 - 3,351,590 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FLT3LG
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1642,653,820 - 42,665,017 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl642,654,412 - 42,660,458 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607322,583,397 - 22,594,517 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Flt3lg
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248324,733,820 - 4,739,214 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression


Sequence


RefSeq Acc Id: ENSCLAT00000005470   ⟹   ENSCLAP00000005374
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049555591,365,938 - 1,369,652 (-)Ensembl
RefSeq Acc Id: ENSCLAT00000005471   ⟹   ENSCLAP00000005375
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049555591,365,938 - 1,369,434 (-)Ensembl
RefSeq Acc Id: ENSCLAT00000005472   ⟹   ENSCLAP00000005376
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0 EnsemblNW_0049555591,368,365 - 1,370,002 (-)Ensembl
RefSeq Acc Id: XM_013509008   ⟹   XP_013364462
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049555591,364,056 - 1,370,036 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013509009   ⟹   XP_013364463
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049555591,364,056 - 1,370,112 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013509010   ⟹   XP_013364464
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049555591,364,056 - 1,370,963 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013509011   ⟹   XP_013364465
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049555591,364,056 - 1,371,066 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013509012   ⟹   XP_013364466
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049555591,364,056 - 1,370,205 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013509013   ⟹   XP_013364467
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049555591,364,056 - 1,371,245 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013509014   ⟹   XP_013364468
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049555591,364,056 - 1,370,214 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013509015   ⟹   XP_013364469
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049555591,364,056 - 1,369,467 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013509016   ⟹   XP_013364470
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049555591,364,056 - 1,369,458 (-)NCBI
Sequence:
RefSeq Acc Id: XM_013509017   ⟹   XP_013364471
Type: CODING
Position:
Chinchilla AssemblyChrPosition (strand)Source
ChiLan1.0NW_0049555591,364,056 - 1,369,451 (-)NCBI
Sequence:
RefSeq Acc Id: XP_013364467   ⟸   XM_013509013
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_013364465   ⟸   XM_013509011
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_013364464   ⟸   XM_013509010
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_013364468   ⟸   XM_013509014
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_013364466   ⟸   XM_013509012
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_013364463   ⟸   XM_013509009
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_013364462   ⟸   XM_013509008
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_013364469   ⟸   XM_013509015
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_013364470   ⟸   XM_013509016
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: XP_013364471   ⟸   XM_013509017
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: ENSCLAP00000005376   ⟸   ENSCLAT00000005472
RefSeq Acc Id: ENSCLAP00000005375   ⟸   ENSCLAT00000005471
RefSeq Acc Id: ENSCLAP00000005374   ⟸   ENSCLAT00000005470


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSCLAG00000003815 Ensembl, UniProtKB/TrEMBL
Ensembl Transcript ENSCLAT00000005470.1 UniProtKB/TrEMBL
  ENSCLAT00000005471.1 UniProtKB/TrEMBL
  ENSCLAT00000005472.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.1250.10 UniProtKB/TrEMBL
InterPro 4_helix_cytokine-like_core UniProtKB/TrEMBL
  Flt3_lig UniProtKB/TrEMBL
NCBI Gene Flt3lg ENTREZGENE
PANTHER FMS-RELATED TYROSINE KINASE 3 LIGAND UniProtKB/TrEMBL
  PTHR11032 UniProtKB/TrEMBL
Pfam Flt3_lig UniProtKB/TrEMBL
Superfamily-SCOP SSF47266 UniProtKB/TrEMBL
UniProt A0A8C2UUC6_CHILA UniProtKB/TrEMBL
  A0A8C2YKH6_CHILA UniProtKB/TrEMBL
  A0A8C2YKI9_CHILA UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-12-10 Flt3lg  fms related receptor tyrosine kinase 3 ligand  Flt3lg  fms related tyrosine kinase 3 ligand  Symbol and/or name change 5135510 APPROVED
2016-08-03 Flt3lg  fms related tyrosine kinase 3 ligand    fms-related tyrosine kinase 3 ligand  Symbol and/or name change 5135510 APPROVED