FLT3LG (fms related receptor tyrosine kinase 3 ligand) - Rat Genome Database

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Gene: FLT3LG (fms related receptor tyrosine kinase 3 ligand) Pan paniscus
Analyze
Symbol: FLT3LG
Name: fms related receptor tyrosine kinase 3 ligand
RGD ID: 12041450
Description: ENCODES a protein that exhibits cytokine activity (inferred); receptor tyrosine kinase binding (inferred); INVOLVED IN B cell differentiation (ortholog); dendritic cell differentiation (ortholog); embryonic hemopoiesis (ortholog); ASSOCIATED WITH aplastic anemia (ortholog); colon carcinoma (ortholog); developmental and epileptic encephalopathy 12 (ortholog); FOUND IN external side of plasma membrane (ortholog)
Type: protein-coding
RefSeq Status: MODEL
Previously known as: fms related tyrosine kinase 3 ligand; fms-related tyrosine kinase 3 ligand
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: Mhudiblu_PPA_v0 - Bonobo Mhudiblu_PPA_v0 Assembly
Position:
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22055,589,080 - 55,601,931 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11957,509,418 - 57,522,277 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01946,486,169 - 46,499,008 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11955,410,448 - 55,422,545 (+)NCBIpanpan1.1PanPan1.1panPan2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
FLT3LG
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v22055,589,080 - 55,601,931 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11957,509,418 - 57,522,277 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01946,486,169 - 46,499,008 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11955,410,448 - 55,422,545 (+)NCBIpanpan1.1PanPan1.1panPan2
FLT3LG
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381949,474,215 - 49,486,231 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1949,474,207 - 49,486,231 (+)EnsemblGRCh38hg38GRCh38
GRCh371949,977,472 - 49,989,488 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361954,669,298 - 54,681,300 (+)NCBINCBI36Build 36hg18NCBI36
Build 341954,669,297 - 54,681,299NCBI
Celera1946,846,847 - 46,858,811 (+)NCBICelera
Cytogenetic Map19q13.33NCBI
HuRef1946,355,067 - 46,367,027 (+)NCBIHuRef
CHM1_11949,978,739 - 49,990,762 (+)NCBICHM1_1
T2T-CHM13v2.01952,474,188 - 52,486,197 (+)NCBIT2T-CHM13v2.0
Flt3l
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39744,780,607 - 44,785,914 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl744,779,212 - 44,785,856 (-)EnsemblGRCm39 Ensembl
GRCm38745,131,183 - 45,136,490 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl745,129,788 - 45,136,432 (-)EnsemblGRCm38mm10GRCm38
MGSCv37752,386,559 - 52,391,802 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36744,999,456 - 45,004,327 (-)NCBIMGSCv36mm8
Celera740,584,281 - 40,589,522 (-)NCBICelera
Cytogenetic Map7B3NCBI
cM Map729.14NCBI
Flt3lg
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81104,751,518 - 104,756,925 (-)NCBIGRCr8
mRatBN7.2195,615,056 - 95,620,463 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl195,609,370 - 95,620,463 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1101,000,447 - 101,005,854 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01109,473,114 - 109,478,521 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01102,763,521 - 102,768,928 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01101,126,006 - 101,131,413 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1101,124,479 - 101,131,413 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01102,190,086 - 102,197,519 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4195,607,131 - 95,611,290 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera189,873,472 - 89,878,870 (-)NCBICelera
Cytogenetic Map1q22NCBI
Flt3lg
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555591,365,938 - 1,370,002 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555591,364,056 - 1,371,245 (-)NCBIChiLan1.0ChiLan1.0
FLT3LG
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11107,015,222 - 107,025,181 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1107,015,223 - 107,024,708 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1106,598,496 - 106,607,982 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01107,535,285 - 107,544,772 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1107,535,286 - 107,545,011 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11107,208,335 - 107,217,819 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01106,850,390 - 106,859,883 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01107,691,506 - 107,700,992 (-)NCBIUU_Cfam_GSD_1.0
Flt3lg
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934921,723,863 - 21,733,400 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366643,343,491 - 3,350,176 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366643,343,541 - 3,351,590 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
FLT3LG
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1642,653,820 - 42,665,017 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl642,654,412 - 42,660,458 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607322,583,397 - 22,594,517 (+)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Flt3lg
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248324,733,820 - 4,739,214 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts XM_014342778 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034944867 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034944868 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034944869 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034944870 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034944872 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034944873 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034944874 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034944875 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034944876 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034944878 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034944879 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034944880 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_034944881 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_055103166 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_055103167 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_055103168 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_055103169 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_055103171 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063599610 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063599611 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063599612 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063599613 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063599614 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063599615 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063599616 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063599617 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063599618 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063599619 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_063599620 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010110777 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_010110778 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide JARIFH020000020 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: XM_034944878   ⟹   XP_034800769
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22055,589,987 - 55,601,800 (+)NCBI
NHGRI_mPanPan11957,509,440 - 57,522,146 (+)NCBI
Mhudiblu_PPA_v01946,486,169 - 46,499,008 (+)NCBI
RefSeq Acc Id: XM_055103166   ⟹   XP_054959141
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22055,589,992 - 55,601,931 (+)NCBI
NHGRI_mPanPan11957,509,429 - 57,522,277 (+)NCBI
RefSeq Acc Id: XM_055103167   ⟹   XP_054959142
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22055,589,992 - 55,601,931 (+)NCBI
NHGRI_mPanPan11957,509,420 - 57,522,277 (+)NCBI
RefSeq Acc Id: XM_055103168   ⟹   XP_054959143
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22055,589,921 - 55,601,931 (+)NCBI
NHGRI_mPanPan11957,509,419 - 57,522,277 (+)NCBI
RefSeq Acc Id: XM_055103169   ⟹   XP_054959144
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22055,589,886 - 55,601,931 (+)NCBI
NHGRI_mPanPan11957,509,422 - 57,522,277 (+)NCBI
RefSeq Acc Id: XM_055103171   ⟹   XP_054959146
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22055,589,992 - 55,601,931 (+)NCBI
NHGRI_mPanPan11957,509,421 - 57,522,152 (+)NCBI
RefSeq Acc Id: XM_063599610   ⟹   XP_063455680
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22055,589,992 - 55,601,931 (+)NCBI
RefSeq Acc Id: XM_063599611   ⟹   XP_063455681
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22055,589,987 - 55,601,931 (+)NCBI
RefSeq Acc Id: XM_063599612   ⟹   XP_063455682
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22055,589,987 - 55,597,979 (+)NCBI
RefSeq Acc Id: XM_063599613   ⟹   XP_063455683
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22055,589,987 - 55,597,663 (+)NCBI
RefSeq Acc Id: XM_063599614   ⟹   XP_063455684
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22055,589,992 - 55,597,980 (+)NCBI
RefSeq Acc Id: XM_063599615   ⟹   XP_063455685
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22055,589,992 - 55,601,931 (+)NCBI
RefSeq Acc Id: XM_063599616   ⟹   XP_063455686
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22055,589,992 - 55,597,680 (+)NCBI
RefSeq Acc Id: XM_063599617   ⟹   XP_063455687
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22055,589,992 - 55,597,981 (+)NCBI
RefSeq Acc Id: XM_063599618   ⟹   XP_063455688
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22055,589,080 - 55,601,931 (+)NCBI
RefSeq Acc Id: XM_063599619   ⟹   XP_063455689
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22055,590,013 - 55,601,931 (+)NCBI
RefSeq Acc Id: XM_063599620   ⟹   XP_063455690
Type: CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22055,589,992 - 55,601,931 (+)NCBI
RefSeq Acc Id: XR_010110777
Type: NON-CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22055,589,992 - 55,601,931 (+)NCBI
RefSeq Acc Id: XR_010110778
Type: NON-CODING
Position:
Bonobo AssemblyChrPosition (strand)Source
NHGRI_mPanPan1-v22055,589,992 - 55,601,772 (+)NCBI
RefSeq Acc Id: XP_034800769   ⟸   XM_034944878
- Peptide Label: isoform X3
RefSeq Acc Id: XP_054959143   ⟸   XM_055103168
- Peptide Label: isoform X12
RefSeq Acc Id: XP_054959142   ⟸   XM_055103167
- Peptide Label: isoform X6
RefSeq Acc Id: XP_054959146   ⟸   XM_055103171
- Peptide Label: isoform X9
RefSeq Acc Id: XP_054959144   ⟸   XM_055103169
- Peptide Label: isoform X13
RefSeq Acc Id: XP_054959141   ⟸   XM_055103166
- Peptide Label: isoform X2
RefSeq Acc Id: XP_063455688   ⟸   XM_063599618
- Peptide Label: isoform X10
RefSeq Acc Id: XP_063455681   ⟸   XM_063599611
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063455682   ⟸   XM_063599612
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063455683   ⟸   XM_063599613
- Peptide Label: isoform X3
RefSeq Acc Id: XP_063455680   ⟸   XM_063599610
- Peptide Label: isoform X1
RefSeq Acc Id: XP_063455685   ⟸   XM_063599615
- Peptide Label: isoform X5
RefSeq Acc Id: XP_063455690   ⟸   XM_063599620
- Peptide Label: isoform X11
RefSeq Acc Id: XP_063455687   ⟸   XM_063599617
- Peptide Label: isoform X8
RefSeq Acc Id: XP_063455684   ⟸   XM_063599614
- Peptide Label: isoform X4
RefSeq Acc Id: XP_063455686   ⟸   XM_063599616
- Peptide Label: isoform X7
RefSeq Acc Id: XP_063455689   ⟸   XM_063599619
- Peptide Label: isoform X10


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSPPAG00000020354 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSPPAT00000022327.1 UniProtKB/TrEMBL
Gene3D-CATH 1.20.1250.10 UniProtKB/TrEMBL
InterPro 4_helix_cytokine-like_core UniProtKB/TrEMBL
  Flt3_lig UniProtKB/TrEMBL
NCBI Gene FLT3LG ENTREZGENE
PANTHER FMS-RELATED TYROSINE KINASE 3 LIGAND UniProtKB/TrEMBL
  PTHR11032 UniProtKB/TrEMBL
Pfam Flt3_lig UniProtKB/TrEMBL
Superfamily-SCOP SSF47266 UniProtKB/TrEMBL
UniProt A0A2R8ZLQ2_PANPA UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2019-12-10 FLT3LG  fms related receptor tyrosine kinase 3 ligand  FLT3LG  fms related tyrosine kinase 3 ligand  Symbol and/or name change 5135510 APPROVED