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Gene: Hspd1 (heat shock protein 1 (chaperonin)) Mus musculus
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Symbol: Hspd1
Name: heat shock protein 1 (chaperonin)
Description: Exhibits lipopolysaccharide binding activity. Involved in several processes, including cellular response to interleukin-7; positive regulation of T cell activation; and positive regulation of cytokine production. Localizes to mitochondrion; plasma membrane; and secretory granule. Used to study hereditary spastic paraplegia 13. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); autistic disorder; glucose intolerance; hereditary spastic paraplegia (multiple); and hypomyelinating leukodystrophy 4. Is expressed in several structures, including brain; eye; and urinary system. Orthologous to human HSPD1 (heat shock protein family D (Hsp60) member 1); PARTICIPATES IN tuberculosis pathway; type 1 diabetes mellitus pathway; INTERACTS WITH 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane; 17alpha-ethynylestradiol; 2,2',4,4'-Tetrabromodiphenyl ether.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 60 kDa chaperonin; 60 kDa heat shock protein, mitochondrial; 60kDa; chaperonin 60; CPN60; heat shock 60kDa protein 1 (chaperonin); heat shock protein 60; heat shock protein, 60 kDa; HSP-60; HSP-65; Hsp60; mitochondrial matrix protein P1
Orthologs:
Homo sapiens (human) : HSPD1 (heat shock protein family D (Hsp60) member 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Hspd1 (heat shock protein family D (Hsp60) member 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Hspd1 (heat shock protein family D (Hsp60) member 1)
Pan paniscus (bonobo/pygmy chimpanzee) : HSPD1 (heat shock protein family D (Hsp60) member 1)
Canis lupus familiaris (dog) : HSPD1 (heat shock protein family D (Hsp60) member 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Hspd1 (heat shock protein family D (Hsp60) member 1)
Sus scrofa (pig) : HSPD1 (heat shock protein family D (Hsp60) member 1)
Chlorocebus sabaeus (African green monkey) : HSPD1 (heat shock protein family D (Hsp60) member 1)
Heterocephalus glaber (naked mole-rat) : Hspd1 (heat shock protein family D (Hsp60) member 1)
more info ...
Related Pseudogenes: Gm12608   Gm12667   Gm13806   Gm14465   Gm14786   Gm14907   Gm14935   Gm15789   Gm16123   Gm17101   Gm17192   Gm18611   Gm18634   Gm18682   Gm20567   Gm20586   Gm20596   Gm4803   Gm5268   Gm6757   Gm7570   Gm7724   Gm8408   Gm8684   Gm9655   Gm9700   Hspd1-ps1   Hspd1-ps2   Hspd1-ps3   Hspd1-ps4   Hspd1-ps5  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl155,077,835 - 55,088,243 (-)EnsemblGRCm38mm10GRCm38
GRCm38155,077,833 - 55,088,243 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37155,134,678 - 55,144,776 (-)NCBIGRCm37mm9NCBIm37
MGSCv36155,022,380 - 55,032,390 (-)NCBImm8
Celera155,597,904 - 55,608,002 (-)NCBICelera
Cytogenetic Map1C1.2NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Hspd1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 733896
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-05-05
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.