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Gene: Xiap (X-linked inhibitor of apoptosis) Mus musculus
Symbol: Xiap
Name: X-linked inhibitor of apoptosis
Description: Predicted to have several functions, including cysteine-type endopeptidase inhibitor activity involved in apoptotic process; scaffold protein binding activity; and ubiquitin protein ligase activity. Involved in inhibition of cysteine-type endopeptidase activity involved in apoptotic process and neuron apoptotic process. Localizes to cytoplasm. Is expressed in several structures, including alimentary system; brain; gallbladder; genitourinary system; and hemolymphoid system gland. Human ortholog(s) of this gene implicated in X-linked lymphoproliferative syndrome 2 and prostate cancer. Orthologous to several human genes including XIAP (X-linked inhibitor of apoptosis).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 1110015C02Rik; Aipa; Api3; apoptosis inhibitor 3; baculoviral IAP repeat-containing 4; baculoviral IAP repeat-containing protein 4; Birc4; E3 ubiquitin-protein ligase XIAP; IAP homolog A; IAP-3; IAP3; ILP-1; inhibitor of apoptosis protein 3; mIAP-3; mIAP3; MIHA; mXIAP; RIKEN cDNA 1110015C02 gene; RING-type E3 ubiquitin transferase XIAP; X-linked IAP; X-linked inhibitor of apoptosis protein
Homo sapiens (human) : XIAP (X-linked inhibitor of apoptosis)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Xiap (X-linked inhibitor of apoptosis)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Xiap (X-linked inhibitor of apoptosis)
Pan paniscus (bonobo/pygmy chimpanzee) : XIAP (X-linked inhibitor of apoptosis)
Canis lupus familiaris (dog) : XIAP (X-linked inhibitor of apoptosis)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Xiap (X-linked inhibitor of apoptosis)
Sus scrofa (pig) : XIAP (X-linked inhibitor of apoptosis)
Chlorocebus sabaeus (African green monkey) : XIAP (X-linked inhibitor of apoptosis)
more info ...
Related Pseudogenes: Gm17791  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 EnsemblX42,059,679 - 42,109,656 (+)EnsemblGRCm38mm10GRCm38
GRCm38X42,059,613 - 42,109,664 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37X39,421,013 - 39,462,841 (+)NCBIGRCm37mm9NCBIm37
MGSCv36X38,338,355 - 38,350,128 (+)NCBImm8
CeleraX29,643,660 - 29,685,399 (+)NCBICelera
Cytogenetic MapXA4NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences
Protein Structures

Additional Information

External Database Links
Nomenclature History
More on Xiap
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 731857
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.