Bnip3 (BCL2/adenovirus E1B interacting protein 3) - Rat Genome Database

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Gene: Bnip3 (BCL2/adenovirus E1B interacting protein 3) Mus musculus
Analyze
Symbol: Bnip3
Name: BCL2/adenovirus E1B interacting protein 3
RGD ID: 733814
MGI Page MGI
Description: Exhibits identical protein binding activity. Involved in several processes, including brown fat cell differentiation; regulation of aerobic respiration; and toxin transport. Localizes to mitochondrial membrane and postsynaptic density. Is expressed in several structures, including central nervous system; embryo mesenchyme; gut; musculoskeletal system; and nasal epithelium. Orthologous to human BNIP3 (BCL2 interacting protein 3); PARTICIPATES IN hypoxia inducible factor pathway; intrinsic apoptotic pathway; mitochondrial autophagy pathway; INTERACTS WITH (+)-dexrazoxane; (S)-nicotine; 1,2-dimethylhydrazine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: BCL2/adenovirus E1B 19 kDa protein-interacting protein 3; BCL2/adenovirus E1B 19 kDa-interacting protein 1, NIP3; BCL2/adenovirus E1B 19kDa-interacting protein 1, NIP3; BCL2/adenovirus E1B interacting protein 1, NIP3; N; Nip3
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Related Pseudogenes: Gm16439   Gm6532   Gm9419  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397138,492,565 - 138,511,235 (-)NCBIGRCm39mm39
GRCm39 Ensembl7138,492,565 - 138,511,248 (-)Ensembl
GRCm387138,890,836 - 138,909,506 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7138,890,836 - 138,909,519 (-)EnsemblGRCm38mm10GRCm38
MGSCv377146,082,519 - 146,101,189 (-)NCBIGRCm37mm9NCBIm37
MGSCv367138,729,179 - 138,747,849 (-)NCBImm8
Celera7138,707,907 - 138,726,495 (-)NCBICelera
Cytogenetic Map7F4NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-dexrazoxane  (EXP)
(+)-epicatechin-3-O-gallate  (ISO)
(+)-pilocarpine  (ISO)
(+)-schisandrin B  (ISO)
(-)-demecolcine  (ISO)
(-)-epigallocatechin 3-gallate  (ISO)
(S)-nicotine  (EXP)
1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane  (ISO)
1,2-dimethylhydrazine  (EXP)
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine  (EXP)
17alpha-ethynylestradiol  (EXP)
1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one  (EXP)
1H-pyrazole  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP)
2,4-dinitrobenzenesulfonic acid  (EXP)
2-hydroxypropanoic acid  (ISO)
2-methoxyethanol  (ISO)
3,3',4,4'-tetrachlorobiphenyl  (EXP)
3-methyladenine  (ISO)
4-hydroxynon-2-enal  (ISO)
5-aza-2'-deoxycytidine  (EXP,ISO)
5-azacytidine  (ISO)
5-fluorouracil  (ISO)
5-methoxy-2-\{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfinyl\}-1H-benzimidazole  (ISO)
6-propyl-2-thiouracil  (ISO)
acetamide  (ISO)
acrylamide  (ISO)
actinomycin D  (EXP)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (EXP)
amiodarone  (ISO)
ammonium chloride  (ISO)
anthra[1,9-cd]pyrazol-6(2H)-one  (ISO)
antimycin A  (EXP)
aristolochic acid  (ISO)
arsenite(3-)  (EXP)
arsenous acid  (ISO)
atrazine  (ISO)
bafilomycin A1  (ISO)
benzbromarone  (ISO)
benzene  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (ISO)
bezafibrate  (EXP)
bicalutamide  (ISO)
bis(2-chloroethyl) sulfide  (ISO)
bisphenol A  (ISO)
bortezomib  (ISO)
buspirone  (ISO)
butan-1-ol  (ISO)
cadmium atom  (EXP,ISO)
cadmium dichloride  (ISO)
caffeine  (EXP)
capsaicin  (ISO)
captan  (EXP)
carbamazepine  (ISO)
carbon nanotube  (EXP)
chloroacetaldehyde  (ISO)
chloropicrin  (ISO)
chloroquine  (ISO)
chlorpromazine  (ISO)
ciguatoxin CTX1B  (EXP)
cisplatin  (EXP,ISO)
clodronic acid  (ISO)
clofibrate  (ISO)
cobalt atom  (ISO)
cobalt dichloride  (EXP,ISO)
cocaine  (EXP)
concanamycin A  (ISO)
copper atom  (EXP)
copper(0)  (EXP)
copper(II) sulfate  (ISO)
crocidolite asbestos  (EXP)
cycloheximide  (EXP)
cyclosporin A  (ISO)
cyfluthrin  (ISO)
cypermethrin  (ISO)
deoxycholic acid  (ISO)
dexamethasone  (EXP,ISO)
diarsenic trioxide  (ISO)
diazinon  (ISO)
dibenz[a,h]anthracene  (EXP)
dibutyl phthalate  (EXP)
dieldrin  (ISO)
diethylstilbestrol  (EXP)
dioxygen  (EXP,ISO)
dopamine  (ISO)
dorsomorphin  (ISO)
doxorubicin  (EXP,ISO)
endosulfan  (ISO)
erlotinib hydrochloride  (ISO)
ethanol  (EXP,ISO)
ethyl methanesulfonate  (ISO)
fenamidone  (EXP)
fenofibrate  (ISO)
fluoranthene  (EXP)
flurbiprofen  (EXP)
folic acid  (ISO)
folpet  (EXP)
formaldehyde  (ISO)
gallic acid  (ISO)
gallocatechin  (ISO)
gefitinib  (ISO)
genistein  (ISO)
geraniol  (ISO)
glutathione  (EXP)
glyphosate  (ISO)
hyaluronic acid  (ISO)
hydrogen peroxide  (ISO)
hydroquinone  (ISO)
ibuprofen  (ISO)
ifosfamide  (ISO)
iron atom  (EXP)
iron(0)  (EXP)
isobutanol  (ISO)
isoflurane  (ISO)
isoprenaline  (EXP)
ivermectin  (EXP)
ketamine  (ISO)
ketoconazole  (ISO)
L-ethionine  (ISO)
lapatinib  (ISO)
leflunomide  (ISO)
lipopolysaccharide  (EXP,ISO)
maneb  (ISO)
manganese atom  (EXP)
manganese(0)  (EXP)
manganese(II) chloride  (EXP)
melatonin  (ISO)
menadione  (EXP)
metformin  (ISO)
methotrexate  (EXP,ISO)
methyl methanesulfonate  (ISO)
methylmercury chloride  (ISO)
methylmercury(1+)  (ISO)
Mitotane  (ISO)
monensin A  (ISO)
motexafin gadolinium  (ISO)
N-[3-(aminomethyl)benzyl]acetamidine  (EXP)
N-acetyl-L-cysteine  (EXP)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (ISO)
N-methyl-4-phenylpyridinium  (EXP,ISO)
N1'-[2-[[5-[(dimethylamino)methyl]-2-furanyl]methylthio]ethyl]-N1-methyl-2-nitroethene-1,1-diamine  (ISO)
nefazodone  (ISO)
nickel dichloride  (EXP,ISO)
nickel subsulfide  (EXP)
nickel sulfate  (ISO)
nicotine  (EXP)
nimesulide  (ISO)
nitric oxide  (EXP,ISO)
nitrogen dioxide  (ISO)
ochratoxin A  (ISO)
omeprazole  (ISO)
oxaliplatin  (ISO)
p-menthan-3-ol  (ISO)
p-toluidine  (ISO)
paeoniflorin  (ISO)
paracetamol  (ISO)
paraquat  (EXP,ISO)
pentobarbital  (ISO)
peroxynitrous acid  (ISO)
pirinixic acid  (EXP,ISO)
pregnenolone 16alpha-carbonitrile  (EXP)
propiconazole  (EXP)
propofol  (EXP)
quercetin  (ISO)
quinolone  (ISO)
rac-lactic acid  (ISO)
ranitidine  (ISO)
rotenone  (EXP,ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (ISO)
S-nitrosoglutathione  (EXP)
SB 431542  (ISO)
simvastatin  (ISO)
sirolimus  (EXP)
sodium arsenite  (ISO)
sodium dichromate  (EXP)
sunitinib  (ISO)
tamoxifen  (EXP)
teriflunomide  (ISO)
tert-butyl hydroperoxide  (EXP,ISO)
tetrachloroethene  (EXP)
tetrachloromethane  (EXP,ISO)
tetraethylenepentamine  (ISO)
thapsigargin  (EXP,ISO)
thimerosal  (ISO)
thioacetamide  (ISO)
titanium dioxide  (EXP)
trichloroethene  (EXP,ISO)
trichostatin A  (ISO)
triptonide  (EXP)
troglitazone  (ISO)
Tungsten carbide  (ISO)
tunicamycin  (ISO)
valdecoxib  (ISO)
valproic acid  (EXP,ISO)
vincristine  (ISO)
vorinostat  (ISO)
zinc acetate  (ISO)
zinc oxide  (ISO)
zoledronic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
apoptotic process  (ISO)
autophagic cell death  (ISO)
brown fat cell differentiation  (IDA)
cardiac muscle cell apoptotic process  (ISO)
cell death  (ISO)
cellular response to cobalt ion  (ISO)
cellular response to hydrogen peroxide  (ISO)
cellular response to hypoxia  (ISO)
cellular response to mechanical stimulus  (ISO)
cerebral cortex development  (ISO)
defense response to virus  (ISO)
granzyme-mediated programmed cell death signaling pathway  (ISO)
intrinsic apoptotic signaling pathway  (IGI,IMP)
intrinsic apoptotic signaling pathway in response to hypoxia  (ISO)
mitochondrial fragmentation involved in apoptotic process  (ISO)
mitochondrial outer membrane permeabilization  (IBA,ISO)
mitochondrial protein catabolic process  (ISO)
negative regulation of apoptotic process  (IGI)
negative regulation of cell death  (ISO)
negative regulation of membrane potential  (ISO)
negative regulation of mitochondrial fusion  (ISO)
negative regulation of mitochondrial membrane permeability involved in apoptotic process  (ISO)
negative regulation of mitochondrial membrane potential  (ISO)
negative regulation of reactive oxygen species metabolic process  (IGI)
neuron apoptotic process  (ISO)
oligodendrocyte differentiation  (ISO)
positive regulation of apoptotic process  (ISO)
positive regulation of autophagy of mitochondrion  (ISO)
positive regulation of cardiac muscle cell apoptotic process  (ISO)
positive regulation of macroautophagy  (ISO)
positive regulation of mitochondrial calcium ion concentration  (ISO)
positive regulation of mitochondrial fission  (ISO)
positive regulation of necrotic cell death  (ISO)
positive regulation of programmed cell death  (IBA,ISO)
positive regulation of protein-containing complex disassembly  (ISO)
positive regulation of release of cytochrome c from mitochondria  (ISO)
reactive oxygen species metabolic process  (ISO)
regulation of aerobic respiration  (IMP)
regulation of mitochondrial membrane permeability  (ISO)
regulation of mitochondrion organization  (IMP)
regulation of programmed cell death  (IBA)
response to axon injury  (ISO)
response to bacterium  (IEP)
response to hyperoxia  (ISO)
response to hypoxia  (ISO)
response to oxygen-glucose deprivation  (ISO)
toxin transport  (IMP)

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
1. Boyd JM, etal., Cell 1994 Oct 21;79(2):341-51.
2. Chaanine AH, etal., Circ Heart Fail. 2013 May;6(3):572-83. doi: 10.1161/CIRCHEARTFAILURE.112.000200. Epub 2013 Mar 18.
3. Dong Y, etal., BMC Complement Altern Med. 2015 Mar 10;15:51. doi: 10.1186/s12906-015-0559-x.
4. Fedorova LV, etal., BMC Nephrol. 2013 Oct 4;14:209. doi: 10.1186/1471-2369-14-209.
5. Hamacher-Brady A, etal., Cell Death Differ. 2007 Jan;14(1):146-57. Epub 2006 Apr 28.
6. Ishihara M, etal., Am J Physiol Renal Physiol. 2013 Aug 15;305(4):F495-509. doi: 10.1152/ajprenal.00642.2012. Epub 2013 May 22.
7. Jannig PR, etal., PLoS One. 2014 Jan 10;9(1):e85820. doi: 10.1371/journal.pone.0085820. eCollection 2014.
8. Jian B, etal., Mol Med. 2011 May-Jun;17(5-6):542-9. doi: 10.2119/molmed.2010.00195. Epub 2010 Dec 22.
9. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
10. Kubli DA and Gustafsson AB, Circ Res. 2012 Oct 12;111(9):1208-21. doi: 10.1161/CIRCRESAHA.112.265819.
11. Lomonosova E and Chinnadurai G, Oncogene. 2008 Dec;27 Suppl 1:S2-19.
12. Lu MC, etal., Obesity (Silver Spring). 2007 Nov;15(11):2634-42.
13. MGD data from the GO Consortium
14. Min JJ, etal., Sci Rep. 2014 Jul 3;4:5555. doi: 10.1038/srep05555.
15. Mootha VK, etal., Cell 2003 Nov 26;115(5):629-40.
16. Neidhardt L, etal., Mech Dev 2000 Nov;98(1-2):77-94.
17. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
18. Pipeline to import Pathway Interaction Database annotations from NCI into RGD
19. Reed JC, etal., Genome Res 2003 Jun;13(6B):1376-88.
20. RGD automated import pipeline
21. RGD automated import pipeline for gene-chemical interactions
22. Schmidt-Kastner R, etal., Brain Res. 2004 Mar 19;1001(1-2):133-42.
23. Shelby SJ, etal., Exp Eye Res. 2015 Aug;137:84-93. doi: 10.1016/j.exer.2015.06.016. Epub 2015 Jun 17.
24. Sowter HM, etal., J Pathol. 2003 Dec;201(4):573-80.
25. Tea M, etal., J Ocul Biol Dis Infor. 2009 Dec 12;2(4):190-201.
26. Wei H, etal., Biochim Biophys Acta. 2015 Oct;1853(10 Pt B):2784-90. doi: 10.1016/j.bbamcr.2015.03.013. Epub 2015 Apr 1.
27. Wu C, etal., Biochem Biophys Res Commun. 2013 Aug 2;437(3):469-74. doi: 10.1016/j.bbrc.2013.06.107. Epub 2013 Jul 9.
28. Yu D, etal., Neurotox Res. 2013 Nov;24(4):512-22. doi: 10.1007/s12640-013-9397-0. Epub 2013 Apr 30.
29. Zamora R, etal., Am J Physiol Gastrointest Liver Physiol. 2005 Nov;289(5):G822-30. Epub 2005 Jul 7.
30. Zhang Z, etal., Stroke. 2007 May;38(5):1606-13. Epub 2007 Mar 22.
Additional References at PubMed
PMID:9867803   PMID:9916985   PMID:10349636   PMID:10725249   PMID:10891486   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11832486   PMID:12477932   PMID:12520002   PMID:14610273  
PMID:15358175   PMID:15489334   PMID:15979417   PMID:16141072   PMID:16141073   PMID:16166637   PMID:16602821   PMID:16874059   PMID:16954213   PMID:17114649   PMID:17170753   PMID:17208939  
PMID:17447897   PMID:17576813   PMID:17623653   PMID:17786027   PMID:17909626   PMID:17928295   PMID:18194653   PMID:18281291   PMID:18492766   PMID:18606473   PMID:18632667   PMID:18799693  
PMID:19147804   PMID:19187620   PMID:19273585   PMID:19321129   PMID:19574421   PMID:19703439   PMID:19915483   PMID:20025887   PMID:20160671   PMID:20185832   PMID:20399150   PMID:20926767  
PMID:21167183   PMID:21267068   PMID:21270129   PMID:21278801   PMID:21415393   PMID:21465467   PMID:21518474   PMID:21868531   PMID:21873635   PMID:21890690   PMID:22044588   PMID:22241963  
PMID:22516201   PMID:22547685   PMID:22753893   PMID:23012479   PMID:23568341   PMID:23692407   PMID:23716698   PMID:24402046   PMID:24625986   PMID:25230377   PMID:25429139   PMID:25489073  
PMID:25753537   PMID:25940086   PMID:26232272   PMID:26253153   PMID:26253785   PMID:26317696   PMID:26505960   PMID:26564789   PMID:26856890   PMID:27325287   PMID:27345388   PMID:27472901  
PMID:27528605   PMID:27689697   PMID:27783443   PMID:27798115   PMID:27861891   PMID:27997827   PMID:28262664   PMID:28333095   PMID:28378742   PMID:28474670   PMID:29149759   PMID:29459731  
PMID:29659575   PMID:30056271   PMID:30062822   PMID:30275982   PMID:30307949   PMID:30482269   PMID:30819186   PMID:31039007   PMID:31142573   PMID:31202927   PMID:31515472   PMID:32277346  
PMID:32894532   PMID:33253203   PMID:33290258  


Genomics

Comparative Map Data
Bnip3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm397138,492,565 - 138,511,235 (-)NCBIGRCm39mm39
GRCm39 Ensembl7138,492,565 - 138,511,248 (-)Ensembl
GRCm387138,890,836 - 138,909,506 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl7138,890,836 - 138,909,519 (-)EnsemblGRCm38mm10GRCm38
MGSCv377146,082,519 - 146,101,189 (-)NCBIGRCm37mm9NCBIm37
MGSCv367138,729,179 - 138,747,849 (-)NCBImm8
Celera7138,707,907 - 138,726,495 (-)NCBICelera
Cytogenetic Map7F4NCBI
BNIP3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl10131,966,455 - 131,982,013 (-)EnsemblGRCh38hg38GRCh38
GRCh3810131,967,684 - 131,981,923 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh3710133,781,187 - 133,795,517 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3610133,631,194 - 133,645,425 (-)NCBINCBI36hg18NCBI36
Build 3410133,631,193 - 133,645,425NCBI
Celera10127,425,370 - 127,439,605 (-)NCBI
Cytogenetic Map10q26.3NCBI
HuRef10127,330,366 - 127,344,602 (-)NCBIHuRef
CHM1_110134,062,287 - 134,076,530 (-)NCBICHM1_1
Bnip3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21193,708,164 - 193,725,348 (-)NCBI
Rnor_6.0 Ensembl1211,248,098 - 211,265,282 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01211,248,098 - 211,265,282 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01218,174,697 - 218,191,883 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41198,683,009 - 198,700,075 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11198,833,000 - 198,850,067 (-)NCBI
Celera1191,399,941 - 191,417,104 (-)NCBICelera
Cytogenetic Map1q41NCBI
Bnip3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554779,621,812 - 9,638,099 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554779,621,812 - 9,630,406 (-)NCBIChiLan1.0ChiLan1.0
BNIP3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.110132,857,375 - 132,871,628 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl10132,858,211 - 132,871,634 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v010128,671,663 - 128,685,952 (-)NCBIMhudiblu_PPA_v0panPan3
BNIP3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12840,037,681 - 40,050,499 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2840,038,643 - 40,049,797 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2840,097,449 - 40,110,338 (-)NCBI
ROS_Cfam_1.02840,678,012 - 40,690,914 (-)NCBI
UMICH_Zoey_3.12840,162,663 - 40,175,507 (-)NCBI
UNSW_CanFamBas_1.02840,150,654 - 40,163,548 (-)NCBI
UU_Cfam_GSD_1.02840,549,677 - 40,562,589 (-)NCBI
Bnip3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_0244072137,077,703 - 7,111,927 (+)NCBI
SpeTri2.0NW_00493648618,449,371 - 18,460,435 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
BNIP3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl14140,362,127 - 140,371,881 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.114140,362,123 - 140,371,951 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.214152,194,909 - 152,204,744 (-)NCBISscrofa10.2Sscrofa10.2susScr3
BNIP3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.19124,570,958 - 124,586,002 (-)NCBI
ChlSab1.1 Ensembl9124,568,695 - 124,585,980 (-)Ensembl
Vero_WHO_p1.0NW_02366604886,009,563 - 86,024,560 (-)NCBI
Bnip3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473714,848,355 - 14,863,731 (+)NCBI

Position Markers
RH136394  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map7F5UniSTS
D18059  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map7F5UniSTS
Whitehead_YAC3 UniSTS
Bnip3  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map7F5UniSTS
cM Map782.95UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301158Eae4_msusceptibility to experimental allergic encephalomyelitis 4 (mouse)Not determined719413473142366067Mouse
27226751Femd5_mfemur midshaft diameter 5, 10 week (mouse)753600000143600000Mouse
27095933Ulnl3_mulna length 3, 5 week (mouse)773500000143600000Mouse
5491192Mobq1_mmultigenic obesity QTL 1 (mouse)Not determined7105651440139651588Mouse
13524852Asrq7a_macoustic startle response 7a (mouse)7105750785139750785Mouse
14700684Civq1_mcerebral infarct volume QTL 1 (mouse)7110108163144108163Mouse
14700687Civq5_mcerebral infarct volume QTL 5 (mouse)7110108163144108163Mouse
14700688Civq6_mcerebral infarct volume QTL 6 (mouse)7110108163144108163Mouse
10402499Lmr21_mleishmaniasis resistance 21 (mouse)Not determined7111365511145365612Mouse
11059562Lmr21b_mleishmaniasis resistance 21b (mouse)7111365511145365612Mouse
1301898Alcp14_malcohol preference locus 14 (mouse)Not determined7111564398145441459Mouse
1302032Alcp12_malcohol preference locus 12 (mouse)Not determined7111564398145441459Mouse
1300670Sluc19_msusceptibility to lung cancer 19 (mouse)Not determined7111564398145441459Mouse
4142444Femwf5_mfemur work to failure 5 (mouse)Not determined112950524145441459Mouse
1300747Skts2_mskin tumor susceptibility 2 (mouse)Not determined7113321003145441459Mouse
1300677Bmd9_mbone mineral density 9 (mouse)Not determined7117032360145441459Mouse
1357711Adbg1_madult body growth 1 (mouse)Not determined7119094158144844577Mouse
1301773Stheal7_msoft tissue heal 7 (mouse)Not determined7119530844145441459Mouse
13207594Nigsq1_mneuroglucopenia-induced glucagon secretion QTL 1 (mouse)7127436844145441459Mouse
1301590Pbwg3_mpostnatal body weight growth 3 (mouse)Not determined7127757504145441459Mouse
1300566Sluc8_msusceptibility to lung cancer 8 (mouse)Not determined7127844414145441459Mouse
14746988Manh63_mmandible shape 63 (mouse)7128181700145441459Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:715
Count of miRNA genes:497
Interacting mature miRNAs:585
Transcripts:ENSMUST00000106112, ENSMUST00000125359, ENSMUST00000130500, ENSMUST00000141223, ENSMUST00000148970
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000106112   ⟹   ENSMUSP00000101718
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl7138,890,836 - 138,909,506 (-)Ensembl
RefSeq Acc Id: ENSMUST00000125359
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl7138,898,710 - 138,909,479 (-)Ensembl
RefSeq Acc Id: ENSMUST00000130500   ⟹   ENSMUSP00000148170
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl7138,894,281 - 138,909,495 (-)Ensembl
RefSeq Acc Id: ENSMUST00000141223
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl7138,894,610 - 138,898,276 (-)Ensembl
RefSeq Acc Id: ENSMUST00000148970
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl7138,898,540 - 138,909,519 (-)Ensembl
RefSeq Acc Id: NM_009760   ⟹   NP_033890
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm397138,492,565 - 138,511,235 (-)NCBI
GRCm387138,890,836 - 138,909,506 (-)ENTREZGENE
MGSCv377146,082,519 - 146,101,189 (-)RGD
Celera7138,707,907 - 138,726,495 (-)RGD
cM Map7 ENTREZGENE
Sequence:
Reference Sequences
RefSeq Acc Id: NP_033890   ⟸   NM_009760
- UniProtKB: O55003 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSMUSP00000148170   ⟸   ENSMUST00000130500
RefSeq Acc Id: ENSMUSP00000101718   ⟸   ENSMUST00000106112

Promoters
RGD ID:8665941
Promoter ID:EPDNEW_M11001
Type:initiation region
Name:Bnip3_1
Description:Mus musculus BCL2/adenovirus E1B interacting protein 3 , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm387138,909,485 - 138,909,545EPDNEW
RGD ID:6840734
Promoter ID:MM_KWN:53093
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6
Transcripts:OTTMUST00000055543
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv367146,089,751 - 146,090,637 (-)MPROMDB
RGD ID:6840735
Promoter ID:MM_KWN:53094
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   3T3L1_Day4,   3T3L1_Day6,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6
Transcripts:NM_009760,   OTTMUST00000055540,   OTTMUST00000055541,   OTTMUST00000055542
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv367146,100,796 - 146,101,667 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:109326 AgrOrtholog
Ensembl Genes ENSMUSG00000031067
  ENSMUSG00000078566 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000101718 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000148170 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000106112 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000130500 UniProtKB/TrEMBL
InterPro BNIP3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:12176 UniProtKB/Swiss-Prot
MGD MGI:109326 ENTREZGENE
NCBI Gene 12176 ENTREZGENE
PANTHER PTHR15186 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam BNIP3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Bnip3 PhenoGen
UniProt A0A1B0GT26_MOUSE UniProtKB/TrEMBL
  A0A2S1CVQ7_MOUSE UniProtKB/TrEMBL
  BNIP3_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary Q544Y4 UniProtKB/Swiss-Prot