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Gene: Bnip3 (BCL2/adenovirus E1B interacting protein 3) Mus musculus
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Symbol: Bnip3
Name: BCL2/adenovirus E1B interacting protein 3
Description: Exhibits protein homodimerization activity. Involved in several processes, including brown fat cell differentiation; intrinsic apoptotic signaling pathway; and regulation of aerobic respiration. Localizes to the mitochondrial membrane and postsynaptic density. Is expressed in several structures, including central nervous system; embryo mesenchyme; gut; musculoskeletal system; and nasal epithelium. Orthologous to human BNIP3 (BCL2 interacting protein 3); PARTICIPATES IN hypoxia inducible factor pathway; intrinsic apoptotic pathway; mitochondrial autophagy pathway; INTERACTS WITH (+)-dexrazoxane; (S)-nicotine; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: BCL2/adenovirus E1B 19 kDa protein-interacting protein 3; BCL2/adenovirus E1B 19 kDa-interacting protein 1, NIP3; BCL2/adenovirus E1B 19kDa-interacting protein 1, NIP3; BCL2/adenovirus E1B interacting protein 1, NIP3; Nip3
Orthologs:
Homo sapiens (human) : BNIP3 (BCL2 interacting protein 3)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Bnip3 (BCL2 interacting protein 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Bnip3 (BCL2 interacting protein 3)
Pan paniscus (bonobo/pygmy chimpanzee) : BNIP3 (BCL2 interacting protein 3)
Canis lupus familiaris (dog) : BNIP3 (BCL2 interacting protein 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Bnip3 (BCL2 interacting protein 3)
Sus scrofa (pig) : BNIP3 (BCL2 interacting protein 3)
more info ...
Related Pseudogenes: Gm16439   Gm6532   Gm9419  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm387138,890,836 - 138,909,506 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv377146,082,519 - 146,101,189 (-)NCBIGRCm37mm9NCBIm37
MGSCv367138,729,179 - 138,747,849 (-)NCBImm8
Celera7138,707,907 - 138,726,495 (-)NCBICelera
Cytogenetic Map7 F4NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Bnip3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 733814
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2019-10-01
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.