Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Bnip3 (BCL2/adenovirus E1B interacting protein 3) Mus musculus
Symbol: Bnip3
Name: BCL2/adenovirus E1B interacting protein 3
Description: Exhibits protein homodimerization activity. Involved in several processes, including brown fat cell differentiation; intrinsic apoptotic signaling pathway; and regulation of aerobic respiration. Localizes to the mitochondrial membrane and postsynaptic density. Is expressed in several structures, including central nervous system; embryo mesenchyme; gut; musculoskeletal system; and nasal epithelium. Orthologous to human BNIP3 (BCL2 interacting protein 3); PARTICIPATES IN hypoxia inducible factor pathway; intrinsic apoptotic pathway; mitochondrial autophagy pathway; INTERACTS WITH (+)-dexrazoxane; (S)-nicotine; 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: BCL2/adenovirus E1B 19 kDa protein-interacting protein 3; BCL2/adenovirus E1B 19 kDa-interacting protein 1, NIP3; BCL2/adenovirus E1B 19kDa-interacting protein 1, NIP3; BCL2/adenovirus E1B interacting protein 1, NIP3; Nip3
Homo sapiens (human) : BNIP3 (BCL2 interacting protein 3)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Bnip3 (BCL2 interacting protein 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Bnip3 (BCL2 interacting protein 3)
Pan paniscus (bonobo/pygmy chimpanzee) : BNIP3 (BCL2 interacting protein 3)
Canis lupus familiaris (dog) : BNIP3 (BCL2 interacting protein 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Bnip3 (BCL2 interacting protein 3)
Sus scrofa (pig) : BNIP3 (BCL2 interacting protein 3)
more info ...
Related Pseudogenes: Gm16439   Gm6532   Gm9419  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm387138,890,836 - 138,909,506 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv377146,082,519 - 146,101,189 (-)NCBIGRCm37mm9NCBIm37
MGSCv367138,729,179 - 138,747,849 (-)NCBImm8
Celera7138,707,907 - 138,726,495 (-)NCBICelera
Cytogenetic Map7 F4NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Bnip3
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 733814
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2019-10-01
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.