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Gene: Hsd3b3 (hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 3) Mus musculus
Symbol: Hsd3b3
Name: hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 3
Description: Predicted to have 3-beta-hydroxy-delta5-steroid dehydrogenase activity. Predicted to be involved in several processes, including C21-steroid hormone metabolic process; hippocampus development; and response to corticosterone. Localizes to the mitochondrial inner membrane. Human ortholog(s) of this gene implicated in hypertension and hypospadias. Is expressed in adrenal gland; liver; and testis medullary region. Orthologous to human HSD3B1 (hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1) and HSD3B2 (hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2); INTERACTS WITH 1,1-dichloroethene; 1H-pyrazole; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 3 beta-hydroxysteroid dehydrogenase 3; 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 3; 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type III; 3-beta-HSD III; 3-beta-hydroxy-5-ene steroid dehydrogenase; 9030618K22Rik; AI790201; delta-5-3-ketosteroid isomerase; hydroxysteroid dehydrogenase-2, delta<5>-3-beta; MGC107584; progesterone reductase; steroid delta-isomerase
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl398,741,523 - 98,763,127 (-)Ensembl
GRCm38398,741,476 - 98,764,540 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37398,545,399 - 98,567,051 (-)NCBIGRCm37mm9NCBIm37
MGSCv36398,870,584 - 98,891,471 (-)NCBImm8
Celera3100,077,484 - 100,099,855 (-)NCBICelera
Cytogenetic Map3 F2.2NCBI
cM Map342.86NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Hsd3b3
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1615187
Created: 2007-04-30
Species: Mus musculus
Last Modified: 2019-11-27
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.