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Gene: Ccne1 (cyclin E1) Mus musculus
Symbol: Ccne1
Name: cyclin E1
Description: Exhibits cyclin-dependent protein serine/threonine kinase regulator activity; kinase activity; and protein kinase binding activity. Involved in several processes, including DNA metabolic process; negative regulation of transcription by RNA polymerase II; and synapsis. Localizes to cyclin E1-CDK2 complex and nucleus. Is expressed in several structures, including Rathke's pouch; brain; early conceptus; eye; and spinal cord. Human ortholog(s) of this gene implicated in breast adenocarcinoma. Orthologous to human CCNE1 (cyclin E1); PARTICIPATES IN G1/S transition pathway; mTOR signaling pathway; cell cycle pathway, mitotic; INTERACTS WITH 1-chloro-2,4-dinitrobenzene; 14-Deoxy-11,12-didehydroandrographolide; 17beta-estradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AW538188; CycE1; G1/S-specific cyclin-E1
Homo sapiens (human) : CCNE1 (cyclin E1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Ccne1 (cyclin E1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ccne1 (cyclin E1)
Pan paniscus (bonobo/pygmy chimpanzee) : CCNE1 (cyclin E1)
Canis lupus familiaris (dog) : CCNE1 (cyclin E1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ccne1 (cyclin E1)
Sus scrofa (pig) : CCNE1 (cyclin E1)
Chlorocebus sabaeus (African green monkey) : CCNE1 (cyclin E1)
Heterocephalus glaber (naked mole-rat) : Ccne1 (cyclin E1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl738,097,984 - 38,107,534 (-)EnsemblGRCm38mm10GRCm38
GRCm38738,097,984 - 38,107,490 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37738,883,003 - 38,892,509 (-)NCBIGRCm37mm9NCBIm37
MGSCv36737,806,744 - 37,816,090 (-)NCBImm8
Celera733,255,165 - 33,271,131 (-)NCBICelera
Cytogenetic Map7B3NCBI
cM Map725.35NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Ccne1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 736489
Created: 2004-02-06
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.