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Gene: Ccne1 (cyclin E1) Mus musculus
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Symbol: Ccne1
Name: cyclin E1
Description: Exhibits cyclin-dependent protein serine/threonine kinase regulator activity; kinase activity; and protein kinase binding activity. Involved in several processes, including DNA metabolic process; negative regulation of transcription by RNA polymerase II; and synapsis. Localizes to cyclin E1-CDK2 complex and nucleus. Is expressed in several structures, including Rathke's pouch; brain; early conceptus; eye; and spinal cord. Human ortholog(s) of this gene implicated in breast adenocarcinoma. Orthologous to human CCNE1 (cyclin E1); PARTICIPATES IN G1/S transition pathway; mTOR signaling pathway; cell cycle pathway, mitotic; INTERACTS WITH 1-chloro-2,4-dinitrobenzene; 14-Deoxy-11,12-didehydroandrographolide; 17beta-estradiol.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AW538188; CycE1; G1/S-specific cyclin-E1
Orthologs:
Homo sapiens (human) : CCNE1 (cyclin E1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Ccne1 (cyclin E1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ccne1 (cyclin E1)
Pan paniscus (bonobo/pygmy chimpanzee) : CCNE1 (cyclin E1)
Canis lupus familiaris (dog) : CCNE1 (cyclin E1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ccne1 (cyclin E1)
Sus scrofa (pig) : CCNE1 (cyclin E1)
Chlorocebus sabaeus (African green monkey) : CCNE1 (cyclin E1)
Heterocephalus glaber (naked mole-rat) : Ccne1 (cyclin E1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 Ensembl738,097,984 - 38,107,534 (-)EnsemblGRCm38mm10GRCm38
GRCm38738,097,984 - 38,107,490 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37738,883,003 - 38,892,509 (-)NCBIGRCm37mm9NCBIm37
MGSCv36737,806,744 - 37,816,090 (-)NCBImm8
Celera733,255,165 - 33,271,131 (-)NCBICelera
Cytogenetic Map7B3NCBI
cM Map725.35NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Ccne1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 736489
Created: 2004-02-06
Species: Mus musculus
Last Modified: 2020-06-30
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.