Astl (astacin like metalloendopeptidase) - Rat Genome Database

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Gene: Astl (astacin like metalloendopeptidase) Mus musculus
Analyze
Symbol: Astl
Name: astacin like metalloendopeptidase
RGD ID: 1556969
MGI Page MGI
Description: Enables aspartic-type peptidase activity and glutamic-type peptidase activity. Involved in several processes, including negative regulation of binding activity of sperm to zona pellucida; positive regulation of protein processing; and prevention of polyspermy. Located in cortical granule and plasma membrane. Is expressed in early conceptus and oocyte. Orthologous to human ASTL (astacin like metalloendopeptidase).
Type: protein-coding
RefSeq Status: VALIDATED
Previously known as: 7420700F21; astacin-like metalloendopeptidase; astacin-like metalloendopeptidase (M12 family); C87576; MGC76457; oocyte astacin; Ov; ovastacin; Sa; Sas1b; sperm acrosomal SLLP1; sperm acrosomal SLLP1-binding protein
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392127,180,559 - 127,199,575 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2127,180,559 - 127,199,571 (+)EnsemblGRCm39 Ensembl
GRCm382127,338,639 - 127,357,655 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2127,338,639 - 127,357,651 (+)EnsemblGRCm38mm10GRCm38
MGSCv372127,164,375 - 127,183,387 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362127,030,080 - 127,049,092 (+)NCBIMGSCv36mm8
Celera2128,584,628 - 128,599,928 (+)NCBICelera
Cytogenetic Map2F1NCBI
cM Map261.93NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Ko MS, etal., Development 2000 Apr;127(8):1737-49.
2. MGDs mouse GO annotations MGD data from the GO Consortium
3. Mouse MP Annotation Import Pipeline RGD automated import pipeline
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:10349636   PMID:10922068   PMID:11042159   PMID:11076861   PMID:11217851   PMID:12466851   PMID:12477932   PMID:15489334   PMID:16141072   PMID:16141073   PMID:17015433   PMID:21267068  
PMID:21677750   PMID:21873635   PMID:22206759   PMID:22275110   PMID:22472438   PMID:27733488   PMID:28114310   PMID:28339615   PMID:28911209   PMID:29358633   PMID:30122633   PMID:34320465  
PMID:37133443  


Genomics

Comparative Map Data
Astl
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392127,180,559 - 127,199,575 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl2127,180,559 - 127,199,571 (+)EnsemblGRCm39 Ensembl
GRCm382127,338,639 - 127,357,655 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2127,338,639 - 127,357,651 (+)EnsemblGRCm38mm10GRCm38
MGSCv372127,164,375 - 127,183,387 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv362127,030,080 - 127,049,092 (+)NCBIMGSCv36mm8
Celera2128,584,628 - 128,599,928 (+)NCBICelera
Cytogenetic Map2F1NCBI
cM Map261.93NCBI
ASTL
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38296,122,818 - 96,138,564 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl296,122,818 - 96,138,502 (-)EnsemblGRCh38hg38GRCh38
GRCh37296,788,557 - 96,804,241 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36296,153,316 - 96,167,902 (-)NCBINCBI36Build 36hg18NCBI36
Build 34296,211,462 - 96,226,049NCBI
Celera291,230,396 - 91,244,982 (-)NCBICelera
Cytogenetic Map2q11.2NCBI
HuRef290,750,866 - 90,765,452 (-)NCBIHuRef
CHM1_1296,793,916 - 96,808,503 (-)NCBICHM1_1
T2T-CHM13v2.0296,629,422 - 96,645,168 (-)NCBIT2T-CHM13v2.0
Astl
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr83135,016,444 - 135,032,177 (+)NCBIGRCr8
mRatBN7.23114,563,135 - 114,580,295 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl3114,563,135 - 114,578,868 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx3118,452,397 - 118,468,141 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.03127,047,958 - 127,063,702 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.03124,708,329 - 124,724,073 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.03119,783,717 - 119,799,450 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3119,783,717 - 119,799,450 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03126,310,094 - 126,325,827 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43114,845,320 - 114,861,053 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera3113,402,096 - 113,417,834 (+)NCBICelera
Cytogenetic Map3q36NCBI
Astl
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554703,719,254 - 3,732,607 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049554703,719,254 - 3,732,598 (-)NCBIChiLan1.0ChiLan1.0
ASTL
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21232,169,814 - 32,185,721 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan12A32,172,596 - 32,188,480 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v02A103,176,662 - 103,192,542 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.12A97,048,871 - 97,063,747 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl2A97,049,184 - 97,063,747 (-)Ensemblpanpan1.1panPan2
ASTL
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11734,594,701 - 34,608,708 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1734,594,026 - 34,607,961 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1734,363,562 - 34,378,272 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01735,365,149 - 35,379,752 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1735,365,007 - 35,379,047 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11734,494,438 - 34,509,160 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01734,562,766 - 34,577,482 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01734,769,924 - 34,784,663 (+)NCBIUU_Cfam_GSD_1.0
Astl
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440629283,005,750 - 83,015,976 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936744259,188 - 268,928 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936744259,188 - 268,919 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ASTL
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl347,059,040 - 47,070,664 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1347,058,104 - 47,071,681 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2349,198,467 - 49,211,812 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ASTL
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.114568,071 - 577,182 (-)NCBIChlSab1.1ChlSab1.1chlSab2
Vero_WHO_p1.0NW_023666041167,978,725 - 167,994,724 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Astl
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247492,241,511 - 2,254,640 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Astl
1104 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1184
Count of miRNA genes:357
Interacting mature miRNAs:406
Transcripts:ENSMUST00000059839, ENSMUST00000089673, ENSMUST00000156747, ENSMUST00000179618
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1301905Lgth2_mbody length 2 (mouse)Not determined2111173704145173821Mouse
1302033Nsv1_mNeuroadapted Sindbis viral RNA level 1 (mouse)Not determined2111623386145623526Mouse
13824983Vclq1_mcurvilinear velocity QTL 1 (mouse)261830344136841920Mouse
13506763Tbvq1_mtrabecular bone volume QTL 1 (mouse)2126041920135441920Mouse
11039520Ltpr2h_mLeishmania tropica response 2h (mouse)2112212746146213005Mouse
11039521Ltpr2g_mLeishmania tropica response 2g (mouse)2115212857149212994Mouse
12910799Pwgrq2_mpre-weaning growth rate QTL 2 (mouse)2118589253160611165Mouse
1302174Dssc2_mdextran sodium sulfate induced colitis QTL2 (mouse)Not determined224224632148700377Mouse
12910795Pwbwq5_mpost-weaning body weight QTL 5 (mouse)2118589253160611165Mouse
27226761Feml18_mfemur length 18, 16 week (mouse)294230345154241920Mouse
12910812Pwgrq1_mpre-weaning growth rate QTL 1 (mouse)2118589253160611165Mouse
12910814Pwbwq1_mpre-weaning body weight QTL 1 (mouse)2118589253160611165Mouse
4141854T2dm2sa_mtype 2 diabetes mellitus 2 in SMXA RI mice (mouse)Not determined229307947148374934Mouse
12904935Edlmmq2_mextensor digitorum longus muscle mass QTL 2 (mouse)297210364131210364Mouse
1302071Fembrs1_mfemur breaking strength 1 (mouse)Not determined2100942930134943090Mouse
10045885Cplaq15_mcircadian period of locomotor activity 15 (mouse)Not determined2110916118154354667Mouse
1302203Gvhd3_mgraft-versus host disease 3 (mouse)Not determined2100942930134943090Mouse
1300793Pcfm2_mperiosteal circumference and femur length 2 (mouse)Not determined2111173704145173821Mouse
10412082Hylaq1_mHyperlocomotor activity related QTL 1 (mouse)Not determined284013198148667470Mouse
1300798Actre3_mactivity response to ethanol 3 (mouse)Not determined2112024987128173821Mouse
1301822Pgia2_mproteoglycan induced arthritis 2 (mouse)Not determined2123937311157937424Mouse
5491197Mobq5_mmultigenic obesity QTL 5 (mouse)Not determined265269746162518926Mouse
5491196Mobq6_mmultigenic obesity QTL 6 (mouse)Not determined285724269180896594Mouse
1301415Actre4_mactivity response to ethanol 4 (mouse)Not determined2112024987128173821Mouse
1301029T2dm3_mtype 2 diabetes mellitus 3 (mouse)Not determined2114288075132714157Mouse
27226788Feml13_mfemur length 13, 10 week (mouse)2102630345159941920Mouse
1301295Prdt1_mprion disease incubation time 1 (mouse)Not determined2116077623150077741Mouse
1301294Hrtfm5_mheart failure modifier 5 (mouse)Not determined2122883015156883131Mouse
12904954Gmmq2_mgastrocnemius muscle mass QTL 2 (mouse)297210364131210364Mouse
11038696Ltpr2f_mLeishmania tropica response 2f (mouse)2115212857149212994Mouse
1301330Tbbmd2_mtotal body bone mineral density 2 (mouse)Not determined2100942930134943090Mouse
1301201Chab1_mcholesterol absorption 1 (mouse)Not determined2111551028145551163Mouse
11038699Ltpr2b_mLeishmania tropica response 2b (mouse)2112212746146213005Mouse
11038700Ltpr2a_mLeishmania tropica response 2a (mouse)2112212746146213005Mouse
11038702Ltpr2_mLeishmania tropica response 2 (mouse)2103095716167212356Mouse
11049568Lmr28c_mleishmaniasis resistance 28c (mouse)297123370131123532Mouse
11049569Lmr28d_mleishmaniasis resistance 28d (mouse)297123370131123532Mouse
11528549Sluc31_msusceptibility to lung cancer 31 (mouse)274524117129213005Mouse
1301087Bbaa15_mB.burgdorferi-associated arthritis 15 (mouse)Not determined2110489658144489807Mouse
1301825Pbrgcsf1_mperipheral blood stem cell response to granulocyte colony stimulating factor 1 (mouse)Not determined2106233580140233729Mouse
4141802Ignpq1_mIgA nephropathy QTL 1 (mouse)Not determined2100824060134824269Mouse
1558990Skmw9_mskeletal muscle weight 9 (mouse)Not determined2111173704145173821Mouse
1301066Otx2m2_morthodenticle homolog 2 (Drosophila) modifier 2 (mouse)Not determined2123231973148700377Mouse
11041906Lmr28a_mleishmaniasis resistance 28a (mouse)2103095716129213005Mouse
4141155Plast2b_mplasma plant sterol 2b (mouse)Not determined284013198148522175Mouse
1301618Bglu1_mblood glucose level 1 (mouse)Not determined2117942930174324863Mouse
27226749Femd10_mfemur midshaft diameter 10, 16 week (mouse)2124441920168241920Mouse
1301755Hrq1_mheart rate quantitative locus 1 (mouse)Not determined2111173704145173821Mouse
1301344Lith1_mlithogenic gene 1 (mouse)Not determined245347635145312647Mouse
1558881Ses7_msalmonella enteritidis susceptibility 7 (mouse)Not determined2116306330150306474Mouse
10043875Bw25_mbody weight QTL 25 (mouse)Not determined2107255676141255676Mouse
1300712El2_mepilepsy 2 (mouse)Not determined2122207146142532135Mouse

Markers in Region
C87576  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm382127,357,201 - 127,357,313UniSTSGRCm38
MGSCv372127,182,937 - 127,183,049UniSTSGRCm37
Celera2128,599,478 - 128,599,590UniSTS
Cytogenetic Map2FUniSTS
Whitehead/MRC_RH21583.59UniSTS
L11330  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm382127,337,974 - 127,338,122UniSTSGRCm38
MGSCv372127,163,710 - 127,163,858UniSTSGRCm37
Cytogenetic Map2F1UniSTS
Cytogenetic Map2FUniSTS
Whitehead/MRC_RH21586.44UniSTS
Astl  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map2FUniSTS
cM Map2 UniSTS


Expression

RNA-SEQ Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001291003 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_172539 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AJ537599 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK033037 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL731836 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL845368 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC064729 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466519 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DV649054 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DV662582 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FJ187790 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FJ187791 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FJ187792 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FJ187793 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FJ187794 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FJ187795 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ404308 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENSMUST00000059839   ⟹   ENSMUSP00000054456
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2127,180,559 - 127,199,571 (+)Ensembl
GRCm38.p6 Ensembl2127,338,639 - 127,357,651 (+)Ensembl
Ensembl Acc Id: ENSMUST00000089673   ⟹   ENSMUSP00000087102
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2127,183,550 - 127,199,570 (+)Ensembl
GRCm38.p6 Ensembl2127,341,630 - 127,357,650 (+)Ensembl
Ensembl Acc Id: ENSMUST00000156747   ⟹   ENSMUSP00000116771
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2127,183,838 - 127,192,088 (+)Ensembl
GRCm38.p6 Ensembl2127,341,918 - 127,350,168 (+)Ensembl
Ensembl Acc Id: ENSMUST00000179618   ⟹   ENSMUSP00000135987
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2127,183,564 - 127,199,569 (+)Ensembl
GRCm38.p6 Ensembl2127,341,644 - 127,357,649 (+)Ensembl
RefSeq Acc Id: NM_001291003   ⟹   NP_001277932
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392127,183,556 - 127,199,575 (+)NCBI
GRCm382127,341,636 - 127,357,655 (+)NCBI
Celera2128,583,915 - 128,599,929 (+)NCBI
Sequence:
RefSeq Acc Id: NM_172539   ⟹   NP_766127
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392127,180,559 - 127,199,575 (+)NCBI
GRCm382127,338,639 - 127,357,655 (+)NCBI
MGSCv372127,164,375 - 127,183,387 (+)RGD
Celera2128,583,915 - 128,599,929 (+)NCBI
cM Map2 ENTREZGENE
Sequence:
RefSeq Acc Id: NP_766127   ⟸   NM_172539
- Peptide Label: isoform b
- UniProtKB: Q6HA09 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001277932   ⟸   NM_001291003
- Peptide Label: isoform a precursor
- UniProtKB: Q6HA09 (UniProtKB/Swiss-Prot),   G7Z019 (UniProtKB/Swiss-Prot),   G7Z018 (UniProtKB/Swiss-Prot),   G7Z017 (UniProtKB/Swiss-Prot),   G7Z016 (UniProtKB/Swiss-Prot),   A2AHU1 (UniProtKB/Swiss-Prot),   A2AHU0 (UniProtKB/Swiss-Prot),   Q8BMA1 (UniProtKB/Swiss-Prot)
- Sequence:
Ensembl Acc Id: ENSMUSP00000054456   ⟸   ENSMUST00000059839
Ensembl Acc Id: ENSMUSP00000135987   ⟸   ENSMUST00000179618
Ensembl Acc Id: ENSMUSP00000087102   ⟸   ENSMUST00000089673
Ensembl Acc Id: ENSMUSP00000116771   ⟸   ENSMUST00000156747
Protein Domains
Peptidase M12A

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q6HA09-F1-model_v2 AlphaFold Q6HA09 1-435 view protein structure

Promoters
RGD ID:6830839
Promoter ID:MM_KWN:31594
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_2Hour,   BoneMarrow_4Hour,   Spleen
Transcripts:NM_172539
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv362127,163,516 - 127,164,822 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:3046414 AgrOrtholog
Ensembl Genes ENSMUSG00000050468 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000059839 ENTREZGENE
  ENSMUST00000059839.9 UniProtKB/Swiss-Prot
  ENSMUST00000089673 ENTREZGENE
  ENSMUST00000089673.10 UniProtKB/Swiss-Prot
  ENSMUST00000156747.2 UniProtKB/TrEMBL
  ENSMUST00000179618.8 UniProtKB/Swiss-Prot
Gene3D-CATH 3.40.390.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro MetalloPept_cat_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Peptidase_M12A UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Peptidase_Metallo UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:215095 UniProtKB/Swiss-Prot
MGD MGI:3046414 ENTREZGENE
NCBI Gene 215095 ENTREZGENE
PANTHER ASTACIN-LIKE METALLOENDOPEPTIDASE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DISCOIDIN, CUB, EGF, LAMININ , AND ZINC METALLOPROTEASE DOMAIN CONTAINING UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Astacin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Astl PhenoGen
PRINTS ASTACIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE ASTACIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZINC_PROTEASE UniProtKB/Swiss-Prot
SMART ZnMc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP Metalloproteases ('zincins'), catalytic domain UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A2AHU0 ENTREZGENE
  A2AHU1 ENTREZGENE
  A2ARG6_MOUSE UniProtKB/TrEMBL
  ASTL_MOUSE UniProtKB/Swiss-Prot
  G7Z016 ENTREZGENE
  G7Z017 ENTREZGENE
  G7Z018 ENTREZGENE
  G7Z019 ENTREZGENE
  Q6HA09 ENTREZGENE
  Q8BMA1 ENTREZGENE
UniProt Secondary A2AHU0 UniProtKB/Swiss-Prot
  A2AHU1 UniProtKB/Swiss-Prot
  G7Z016 UniProtKB/Swiss-Prot
  G7Z017 UniProtKB/Swiss-Prot
  G7Z018 UniProtKB/Swiss-Prot
  G7Z019 UniProtKB/Swiss-Prot
  Q8BMA1 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2023-06-27 Astl  astacin like metalloendopeptidase  Astl  astacin-like metalloendopeptidase (M12 family)  Symbol and/or name change 5135510 APPROVED