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Gene: Il3 (interleukin 3) Mus musculus
Symbol: Il3
Name: interleukin 3
Description: Exhibits cytokine activity; growth factor activity; and interleukin-3 receptor binding activity. Involved in several processes, including cell surface receptor signaling pathway; monocyte differentiation; and regulation of phosphate metabolic process. Localizes to extracellular space. Is expressed in skin; stomach; thymus; and vascular system. Human ortholog(s) of this gene implicated in Graves' disease; asthma; and rheumatoid arthritis. Orthologous to human IL3 (interleukin 3); PARTICIPATES IN Fc epsilon receptor mediated signaling pathway; interleukin-3 signaling pathway; apoptotic cell death pathway; INTERACTS WITH 1-chloro-2,4-dinitrobenzene; 2,3,7,8-tetrachlorodibenzodioxine; 3,5-diethoxycarbonyl-1,4-dihydrocollidine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: BPA; Csfmu; HCGF; hematopoietic growth factor; Il-3; interleukin-3; mast cell growth factor; MCGF; multipotential colony-stimulating factor; P-cell-stimulating factor; PSF
Homo sapiens (human) : IL3 (interleukin 3)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Il3 (interleukin 3)  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : IL3 (interleukin 3)
Canis lupus familiaris (dog) : IL3 (interleukin 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Il3 (interleukin 3)
Chlorocebus sabaeus (African green monkey) : IL3 (interleukin 3)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl1154,265,303 - 54,267,277 (-)EnsemblGRCm38mm10GRCm38
GRCm381154,265,085 - 54,267,279 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371154,078,587 - 54,080,781 (-)NCBIGRCm37mm9NCBIm37
MGSCv361154,108,726 - 54,110,700 (-)NCBImm8
Celera1158,854,078 - 58,856,272 (-)NCBICelera
Cytogenetic Map11B1.3NCBI
cM Map1132.13NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Il3
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 10793
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-07-07
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.