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Gene: Mapk10 (mitogen-activated protein kinase 10) Mus musculus
Symbol: Mapk10
Name: mitogen-activated protein kinase 10
Description: Exhibits JUN kinase activity. Involved in several processes, including JNK cascade; locomotor rhythm; and regulation of circadian rhythm. Localizes to mitochondrion; plasma membrane; and postsynaptic density. Is expressed in several structures, including genitourinary system; gut; heart; nervous system; and sensory organ. Human ortholog(s) of this gene implicated in pancreatic adenocarcinoma. Orthologous to human MAPK10 (mitogen-activated protein kinase 10).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: c-Jun N-terminal kinase 3; C230008H04Rik; JNK; JNK3; JNK3 beta1 protein kinase; JNK3 beta2 protein kinase; JNK3B1; JNK3B2; MAP kinase 10; MAP kinase p49 3F12; MAPK 10; mitogen activated protein kinase 10; p493F1; p493F12; p54bSAPK; SAPK(beta); SAPK/Erk/kinase 2; Ser; Serk2; stress-activated protein kinase JNK3
Homo sapiens (human) : MAPK10 (mitogen-activated protein kinase 10)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Mapk10 (mitogen activated protein kinase 10)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mapk10 (mitogen-activated protein kinase 10)
Pan paniscus (bonobo/pygmy chimpanzee) : MAPK10 (mitogen-activated protein kinase 10)
Canis lupus familiaris (dog) : MAPK10 (mitogen-activated protein kinase 10)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mapk10 (mitogen-activated protein kinase 10)
Sus scrofa (pig) : MAPK10 (mitogen-activated protein kinase 10)
Chlorocebus sabaeus (African green monkey) : MAPK10 (mitogen-activated protein kinase 10)
Heterocephalus glaber (naked mole-rat) : Mapk10 (mitogen-activated protein kinase 10)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl5102,907,948 - 103,211,334 (-)EnsemblGRCm38mm10GRCm38
GRCm385102,908,547 - 103,212,604 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv375103,336,967 - 103,640,353 (-)NCBIGRCm37mm9NCBIm37
MGSCv365103,152,671 - 103,451,379 (-)NCBImm8
Celera5100,221,882 - 100,523,871 (-)NCBICelera
Cytogenetic Map5E5NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Mapk10
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 11285
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-09-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.