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Gene: Alk (anaplastic lymphoma kinase) Mus musculus
Symbol: Alk
Name: anaplastic lymphoma kinase
Description: Predicted to have identical protein binding activity and transmembrane receptor protein tyrosine kinase activity. Involved in several processes, including nervous system development; response to environmental enrichment; and swimming behavior. Predicted to localize to several cellular components, including the axon; cell body; and integral component of plasma membrane. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; nervous system; and sensory organ. Orthologous to human ALK (ALK receptor tyrosine kinase); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; chlorpyrifos; choline.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: ALK tyrosine kinase receptor; CD246; Tcrz
Homo sapiens (human) : ALK (ALK receptor tyrosine kinase)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Alk (ALK receptor tyrosine kinase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Alk (ALK receptor tyrosine kinase)
Pan paniscus (bonobo/pygmy chimpanzee) : ALK (ALK receptor tyrosine kinase)
Canis lupus familiaris (dog) : ALK (ALK receptor tyrosine kinase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Alk (ALK receptor tyrosine kinase)
Sus scrofa (pig) : ALK (ALK receptor tyrosine kinase)
Chlorocebus sabaeus (African green monkey) : ALK (ALK receptor tyrosine kinase)
Heterocephalus glaber (naked mole-rat) : Alk (ALK receptor tyrosine kinase)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1771,868,972 - 72,604,627 (-)Ensembl
GRCm381771,868,988 - 72,604,702 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371772,218,328 - 72,953,647 (-)NCBIGRCm37mm9NCBIm37
MGSCv361771,773,845 - 72,508,684 (-)NCBImm8
MGSCv361771,009,971 - 71,745,160 (-)NCBImm8
Celera1776,136,594 - 76,877,724 (-)NCBICelera
Cytogenetic Map17 E1.3NCBI
cM Map1743.77NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Alk
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1553242
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2020-01-28
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.