Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Hmga2 (high mobility group AT-hook 2) Mus musculus
Analyze
Symbol: Hmga2
Name: high mobility group AT-hook 2
Description: Exhibits AT DNA binding activity and DNA-binding transcription activator activity, RNA polymerase II-specific. Involved in several processes, including animal organ development; negative regulation of cellular senescence; and positive regulation of cell population proliferation. Localizes to the nuclear chromosome. Human ortholog(s) of this gene implicated in leiomyoma; lipoma; ovarian cancer; and uterine fibroid. Is expressed in several structures, including alimentary system; brain; genitourinary system; limb long bone; and sensory organ. Orthologous to human HMGA2 (high mobility group AT-hook 2); PARTICIPATES IN Ras mediated signaling pathway; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; 2,4-diaminotoluene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 9430083A20Rik; high mobility group AT-hook protein 2; high mobility group protein HMGI-C; high mobility group protein I, isoform C; HMGI-C; Hmgic; MGC103393; pg; pygmy
Orthologs:
Homo sapiens (human) : HMGA2 (high mobility group AT-hook 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Hmga2 (high mobility group AT-hook 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Hmga2 (high mobility group AT-hook 2)
Canis lupus familiaris (dog) : HMGA2 (high mobility group AT-hook 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Hmga2 (high mobility group AT-hook 2)
Sus scrofa (pig) : HMGA2 (high mobility group AT-hook 2)
more info ...
Related Pseudogenes: Hmga2-ps1  
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm3810120,361,268 - 120,476,469 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv3710119,798,331 - 119,913,991 (-)NCBIGRCm37mm9NCBIm37
MGSCv3610119,764,721 - 119,880,028 (-)NCBImm8
Celera10122,723,179 - 122,838,757 (-)NCBICelera
Cytogenetic Map10 D2NCBI
cM Map1067.94NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Hmga2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1552855
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2019-09-12
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.