Gene-Chemical Interaction Annotations Click to see Annotation Detail View
Term | Qualifier | Evidence | With | Reference | Notes | Source | Original Reference(s) | 1,2-dichloroethane | increases expression | EXP | | 6480464 | ethylene dichloride results in increased expression of ABCG4 mRNA | CTD | PMID:28960355 | 1,2-dimethylhydrazine | multiple interactions | EXP | | 6480464 | Folic Acid inhibits the reaction [1 and 2-Dimethylhydrazine results in decreased expression of ABCG4 mRNA] | CTD | PMID:22206623 | 1,2-dimethylhydrazine | decreases expression | EXP | | 6480464 | 1 and 2-Dimethylhydrazine results in decreased expression of ABCG4 mRNA | CTD | PMID:22206623 | 17beta-estradiol | multiple interactions | ISO | Abcg4 (Rattus norvegicus) | 6480464 | [bisphenol A co-treated with Estradiol] results in decreased expression of ABCG4 mRNA | CTD | PMID:26496021 | 17beta-estradiol | multiple interactions | ISO | ABCG4 (Homo sapiens) | 6480464 | [Estradiol co-treated with TGFB1 protein] results in increased expression of ABCG4 mRNA | CTD | PMID:30165855 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | ISO | Abcg4 (Rattus norvegicus) | 6480464 | Tetrachlorodibenzodioxin affects the expression of ABCG4 mRNA | CTD | PMID:22298810 | 2,3,7,8-tetrachlorodibenzodioxine | affects expression | EXP | | 6480464 | Tetrachlorodibenzodioxin affects the expression of ABCG4 mRNA | CTD | PMID:21570461 | 3,4-methylenedioxymethamphetamine | increases expression | EXP | | 6480464 | N-Methyl-3 and 4-methylenedioxyamphetamine results in increased expression of ABCG4 mRNA | CTD | PMID:20188158 | 4-hydroxyphenyl retinamide | decreases expression | EXP | | 6480464 | Fenretinide results in decreased expression of ABCG4 mRNA | CTD | PMID:28973697 | 6-propyl-2-thiouracil | decreases expression | ISO | Abcg4 (Rattus norvegicus) | 6480464 | Propylthiouracil results in decreased expression of ABCG4 mRNA | CTD | PMID:30047161 | acetamide | increases expression | ISO | Abcg4 (Rattus norvegicus) | 6480464 | acetamide results in increased expression of ABCG4 mRNA | CTD | PMID:31881176 | aflatoxin B1 | increases expression | ISO | ABCG4 (Homo sapiens) | 6480464 | Aflatoxin B1 results in increased expression of ABCG4 mRNA | CTD | PMID:22100608 | amitrole | decreases expression | ISO | Abcg4 (Rattus norvegicus) | 6480464 | Amitrole results in decreased expression of ABCG4 mRNA | CTD | PMID:30047161 | arsane | multiple interactions | ISO | ABCG4 (Homo sapiens) | 6480464 | [sodium arsenate results in increased abundance of Arsenic] which results in decreased expression of ABCG4 mRNA | CTD | PMID:32525701 | arsenic atom | multiple interactions | ISO | ABCG4 (Homo sapiens) | 6480464 | [sodium arsenate results in increased abundance of Arsenic] which results in decreased expression of ABCG4 mRNA | CTD | PMID:32525701 | benzo[a]pyrene | increases expression | EXP | | 6480464 | Benzo(a)pyrene results in increased expression of ABCG4 mRNA | CTD | PMID:22228805 | benzo[a]pyrene | increases expression | ISO | ABCG4 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased expression of ABCG4 mRNA | CTD | PMID:32234424 | benzo[a]pyrene | increases methylation | ISO | ABCG4 (Homo sapiens) | 6480464 | Benzo(a)pyrene results in increased methylation of ABCG4 3' UTR | CTD | PMID:27901495 | benzo[a]pyrene | affects methylation | ISO | ABCG4 (Homo sapiens) | 6480464 | Benzo(a)pyrene affects the methylation of ABCG4 promoter | CTD | PMID:27901495 | benzo[b]fluoranthene | decreases expression | EXP | | 6480464 | benzo(b)fluoranthene results in decreased expression of ABCG4 mRNA | CTD | PMID:26377693 | bisphenol A | multiple interactions | ISO | Abcg4 (Rattus norvegicus) | 6480464 | [bisphenol A co-treated with Estradiol] results in decreased expression of ABCG4 mRNA and [bisphenol A co-treated with Testosterone] results in decreased expression of ABCG4 mRNA | CTD | PMID:26496021 | bisphenol A | decreases expression | EXP | | 6480464 | bisphenol A results in decreased expression of ABCG4 mRNA | CTD | PMID:32156529 | bisphenol A | decreases expression | ISO | Abcg4 (Rattus norvegicus) | 6480464 | bisphenol A results in decreased expression of ABCG4 mRNA | CTD | PMID:30816183 | butanal | increases expression | ISO | ABCG4 (Homo sapiens) | 6480464 | butyraldehyde results in increased expression of ABCG4 mRNA | CTD | PMID:26079696 | chlorpyrifos | affects expression | EXP | | 6480464 | Chlorpyrifos affects the expression of ABCG4 mRNA | CTD | PMID:37019170 | cisplatin | increases expression | ISO | ABCG4 (Homo sapiens) | 6480464 | Cisplatin results in increased expression of ABCG4 mRNA | CTD | PMID:27392435 | cisplatin | multiple interactions | ISO | ABCG4 (Homo sapiens) | 6480464 | [Cisplatin co-treated with jinfukang] results in increased expression of ABCG4 mRNA | CTD | PMID:27392435 | dibutyl phthalate | decreases expression | EXP | | 6480464 | Dibutyl Phthalate results in decreased expression of ABCG4 mRNA | CTD | PMID:21266533 | endosulfan | increases expression | ISO | Abcg4 (Rattus norvegicus) | 6480464 | Endosulfan results in increased expression of ABCG4 mRNA | CTD | PMID:29391264 | ethylparaben | decreases expression | ISO | ABCG4 (Homo sapiens) | 6480464 | ethyl-p-hydroxybenzoate results in decreased expression of ABCG4 mRNA | CTD | PMID:37690743 | exemestane | increases expression | ISO | ABCG4 (Homo sapiens) | 6480464 | exemestane results in increased expression of ABCG4 mRNA | CTD | PMID:17254854 | fenvalerate | increases expression | ISO | Abcg4 (Rattus norvegicus) | 6480464 | fenvalerate results in increased expression of ABCG4 mRNA | CTD | PMID:30307764 | folic acid | decreases expression | EXP | | 6480464 | Folic Acid results in decreased expression of ABCG4 mRNA | CTD | PMID:25629700 | folic acid | multiple interactions | EXP | | 6480464 | Folic Acid inhibits the reaction [1 and 2-Dimethylhydrazine results in decreased expression of ABCG4 mRNA] | CTD | PMID:22206623 | indole-3-methanol | multiple interactions | ISO | Abcg4 (Rattus norvegicus) | 6480464 | [indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of ABCG4 mRNA more ... | CTD | PMID:22129741 | lead(0) | affects expression | ISO | ABCG4 (Homo sapiens) | 6480464 | Lead affects the expression of ABCG4 mRNA | CTD | PMID:28903495 | methimazole | decreases expression | ISO | Abcg4 (Rattus norvegicus) | 6480464 | Methimazole results in decreased expression of ABCG4 mRNA | CTD | PMID:30047161 | methotrexate | affects expression | EXP | | 6480464 | Methotrexate affects the expression of ABCG4 mRNA | CTD | PMID:18502557 | N-acetyl-L-cysteine | multiple interactions | ISO | Abcg4 (Rattus norvegicus) | 6480464 | [indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of ABCG4 mRNA and Acetylcysteine inhibits the reaction [[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of ABCG4 mRNA] | CTD | PMID:22129741 | N-nitrosodiethylamine | multiple interactions | ISO | Abcg4 (Rattus norvegicus) | 6480464 | [indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of ABCG4 mRNA more ... | CTD | PMID:22129741 | niclosamide | increases expression | ISO | ABCG4 (Homo sapiens) | 6480464 | Niclosamide results in increased expression of ABCG4 mRNA | CTD | PMID:36318118 | nitrofen | decreases expression | ISO | Abcg4 (Rattus norvegicus) | 6480464 | nitrofen results in decreased expression of ABCG4 mRNA | CTD | PMID:33484710 | ochratoxin A | increases expression | ISO | Abcg4 (Rattus norvegicus) | 6480464 | ochratoxin A results in increased expression of ABCG4 mRNA | CTD | PMID:37162024 | ochratoxin A | decreases methylation | ISO | Abcg4 (Rattus norvegicus) | 6480464 | ochratoxin A results in decreased methylation of ABCG4 gene | CTD | PMID:37162024 | oxaliplatin | multiple interactions | ISO | Abcg4 (Rattus norvegicus) | 6480464 | [oxaliplatin co-treated with Topotecan] results in decreased expression of ABCG4 mRNA | CTD | PMID:25729387 | oxaliplatin | decreases expression | ISO | Abcg4 (Rattus norvegicus) | 6480464 | oxaliplatin results in decreased expression of ABCG4 mRNA | CTD | PMID:25729387 | paracetamol | increases expression | ISO | Abcg4 (Rattus norvegicus) | 6480464 | Acetaminophen results in increased expression of ABCG4 mRNA | CTD | PMID:33387578 | pentanal | increases expression | ISO | ABCG4 (Homo sapiens) | 6480464 | pentanal results in increased expression of ABCG4 mRNA | CTD | PMID:26079696 | potassium dichromate | increases expression | EXP | | 6480464 | Potassium Dichromate results in increased expression of ABCG4 mRNA | CTD | PMID:23608068 | propanal | increases expression | ISO | ABCG4 (Homo sapiens) | 6480464 | propionaldehyde results in increased expression of ABCG4 mRNA | CTD | PMID:26079696 | sodium arsenate | multiple interactions | ISO | ABCG4 (Homo sapiens) | 6480464 | [sodium arsenate results in increased abundance of Arsenic] which results in decreased expression of ABCG4 mRNA | CTD | PMID:32525701 | sulfadimethoxine | decreases expression | ISO | Abcg4 (Rattus norvegicus) | 6480464 | Sulfadimethoxine results in decreased expression of ABCG4 mRNA | CTD | PMID:30047161 | sunitinib | decreases expression | ISO | ABCG4 (Homo sapiens) | 6480464 | Sunitinib results in decreased expression of ABCG4 mRNA | CTD | PMID:31533062 | testosterone | multiple interactions | ISO | Abcg4 (Rattus norvegicus) | 6480464 | [bisphenol A co-treated with Testosterone] results in decreased expression of ABCG4 mRNA | CTD | PMID:26496021 | testosterone | decreases expression | ISO | ABCG4 (Homo sapiens) | 6480464 | Testosterone results in decreased expression of ABCG4 mRNA | CTD | PMID:33359661 | topotecan | multiple interactions | ISO | Abcg4 (Rattus norvegicus) | 6480464 | [oxaliplatin co-treated with Topotecan] results in decreased expression of ABCG4 mRNA | CTD | PMID:25729387 | topotecan | decreases expression | ISO | Abcg4 (Rattus norvegicus) | 6480464 | Topotecan results in decreased expression of ABCG4 mRNA | CTD | PMID:25729387 | triptonide | increases expression | EXP | | 6480464 | triptonide results in increased expression of ABCG4 mRNA | CTD | PMID:33045310 | vincristine | multiple interactions | ISO | ABCG4 (Homo sapiens) | 6480464 | [Vincristine results in decreased susceptibility to Vincristine] which results in decreased expression of ABCG4 mRNA | CTD | PMID:19944135 | |