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Gene: Nthl1 (nth (endonuclease III)-like 1 (E.coli)) Mus musculus
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Symbol: Nthl1
Name: nth (endonuclease III)-like 1 (E.coli)
Description: ENCODES a protein that exhibits DNA N-glycosylase activity; DNA-(apurinic or apyrimidinic site) endonuclease activity; class I DNA-(apurinic or apyrimidinic site) endonuclease activity (ortholog); INVOLVED IN nucleotide-excision repair, DNA incision, 5'-to lesion; base-excision repair, AP site formation (ortholog); PARTICIPATES IN base excision repair pathway; ASSOCIATED WITH abnormal DNA repair; ASSOCIATED WITH Acute Hepatitis (ortholog); familial adenomatous polyposis (ortholog); familial adenomatous polyposis 3 (ortholog); FOUND IN mitochondrion; nucleus; INTERACTS WITH 17alpha-ethynylestradiol; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: bifunctional DNA N-glycoslyase/DNA-(apurinic or apyrimidinic site) lyase; bifunctional DNA N-glycosylase/DNA-(apurinic or apyrimidinic site) lyase; DNA glycoslyase/AP lyase; DNA glycosylase/AP lyase; endonuclease III-like protein 1; Nth1; Octs3; thymine glycol DNA glycosylase/AP lyase
Orthologs:
Homo sapiens (human) : NTHL1 (nth like DNA glycosylase 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Nthl1 (nth-like DNA glycosylase 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nthl1 (nth like DNA glycosylase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : NTHL1 (nth like DNA glycosylase 1)
Canis lupus familiaris (dog) : NTHL1 (nth like DNA glycosylase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nthl1 (nth like DNA glycosylase 1)
Sus scrofa (pig) : NTHL1 (nth like DNA glycosylase 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm381724,632,680 - 24,638,838 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371724,769,627 - 24,775,783 (+)NCBIGRCm37mm9NCBIm37
MGSCv361724,360,310 - 24,366,437 (+)NCBImm8
Celera1725,155,083 - 25,161,227 (+)NCBICelera
Cytogenetic Map17 A3.3NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Nthl1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1319555
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2019-09-12
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.