N-acetyl-amino acid - Ontology Report - Rat Genome Database

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CHEBI ONTOLOGY - ANNOTATIONS

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The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:	N-acetyl-amino acid	go back to main search page
Accession:	CHEBI:21575	browse the term
Definition:	An N-acyl-amino acid that has acetyl as the acyl group.
Synonyms:	related_synonym:	N-acetyl-amino acids
	alt_id:	CHEBI:7105
	xref:	KEGG:C02847

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Genes (989)

Ac-Asp-Glu

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

folate hydrolase 1

affects binding
multiple interactions

isospaglumic acid binds to FOLH1 protein
[2-(3-(1,3-dicarboxypropyl)ureido)pentanedioic acid binds to Aminocaproic Acid binds to 1-(1,3-carboxypropyl)-4,7-carboxymethyl-1,4,7-triazacyclononane binds to Valerates binds to bombesin (7-14) binds to Copper] inhibits the reaction [isospaglumic acid binds to FOLH1 protein]

NCBI chr 1:140,428,101...140,501,563
Ensembl chr 1:140,428,101...140,501,379

N-acetyl-L-cysteine

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

alpha-1-B glycoprotein

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of A1BG mRNA; Acetylcysteine inhibits the reaction [[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of A1BG mRNA]

NCBI chr 7:92,493,934...92,498,460
Ensembl chr 7:92,494,372...92,498,097

G

ATP binding cassette subfamily A member 1

multiple interactions

Acetylcysteine inhibits the reaction [sodium arsenite results in decreased expression of ABCA1 mRNA]; Acetylcysteine inhibits the reaction [sodium arsenite results in decreased expression of ABCA1 protein]; Acetylcysteine inhibits the reaction [sodium arsenite results in increased methylation of ABCA1 promoter]

NCBI chr 5:67,678,267...67,801,162
Ensembl chr 5:67,681,297...67,801,170

G

ATP binding cassette subfamily A member 5

multiple interactions

Acetylcysteine inhibits the reaction [sodium arsenite results in decreased expression of ABCA5 mRNA]

NCBI chr10:95,240,159...95,309,195
Ensembl chr10:95,240,154...95,308,976

G

ATP binding cassette subfamily B member 1A

multiple interactions

Acetylcysteine affects the reaction [[gambogic acid affects the reaction [ABCB1 protein affects the susceptibility to Doxorubicin]] which affects the cleavage of CASP7 protein]; Acetylcysteine affects the reaction [[gambogic acid affects the reaction [ABCB1 protein affects the susceptibility to Doxorubicin]] which affects the cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [3',4',7-trihydroxyisoflavone results in decreased expression of ABCB1 mRNA]; Acetylcysteine inhibits the reaction [formononetin results in increased expression of ABCB1 mRNA]
Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of ABCB1]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of and results in increased activity of ABCB1 protein]; Acetylcysteine inhibits the reaction [Vehicle Emissions results in increased expression of and results in increased activity of ABCB1 protein]

PMID:10636889 PMID:18474546 PMID:22914566 PMID:23867903 PMID:25824409

NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709

G

ATP binding cassette subfamily C member 1

multiple interactions

Acetylcysteine inhibits the reaction [3',4',7-trihydroxyisoflavone results in decreased expression of ABCC1 mRNA]; Acetylcysteine inhibits the reaction [formononetin results in decreased expression of ABCC1 mRNA]; Acetylcysteine inhibits the reaction [Sulindac results in increased expression of ABCC1 protein]; Acetylcysteine promotes the reaction [ABCC1 protein results in decreased susceptibility to Doxorubicin]; Buthionine Sulfoximine analog inhibits the reaction [Acetylcysteine promotes the reaction [ABCC1 protein results in decreased susceptibility to Doxorubicin]]

PMID:11820781 PMID:15473893 PMID:22914566 PMID:23867903

NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114

G

ATP binding cassette subfamily C member 2

multiple interactions

Acetylcysteine inhibits the reaction [3',4',7-trihydroxyisoflavone results in decreased expression of ABCC2 mRNA]; Acetylcysteine inhibits the reaction [formononetin results in decreased expression of ABCC2 mRNA]
Acetylcysteine inhibits the reaction [tert-Butylhydroperoxide affects the localization of ABCC2 protein]

PMID:22914566 PMID:23867903 PMID:34303734

NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238

G

ATP binding cassette subfamily C member 3

multiple interactions

Acetylcysteine inhibits the reaction [Sulindac results in increased expression of ABCC3 protein]

NCBI chr10:79,296,681...79,342,749
Ensembl chr10:79,296,693...79,342,595

G

ATP binding cassette subfamily G member 1

decreases expression

Acetylcysteine results in decreased expression of ABCG1 mRNA

NCBI chr20:9,126,687...9,182,948
Ensembl chr20:9,126,687...9,182,948

G

ATP binding cassette subfamily G member 4

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of ABCG4 mRNA; Acetylcysteine inhibits the reaction [[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of ABCG4 mRNA]

NCBI chr 8:44,611,187...44,629,818
Ensembl chr 8:44,611,187...44,626,881

G

ABL proto-oncogene 1, non-receptor tyrosine kinase

multiple interactions

Acetylcysteine inhibits the reaction [NSC 680410 results in decreased phosphorylation of ABL1 protein]

NCBI chr 3:14,979,853...15,083,065
Ensembl chr 3:14,979,853...15,083,065

G

acetylcholinesterase

multiple interactions
affects response to substance

[Zinc co-treated with Selenium co-treated with Acetylcysteine] inhibits the reaction [dimethyl mercury results in decreased activity of ACHE protein]; Acetylcysteine inhibits the reaction [Cadmium results in decreased activity of ACHE protein]; Acetylcysteine inhibits the reaction [Chlorpyrifos results in decreased activity of ACHE protein]; Acetylcysteine inhibits the reaction [chlorpyrifos-methyl results in decreased activity of ACHE protein]; Acetylcysteine inhibits the reaction [Dimethoate results in decreased activity of ACHE protein]; Acetylcysteine inhibits the reaction [Fenitrothion results in decreased activity of ACHE protein]; Acetylcysteine inhibits the reaction [Fenitrothion results in decreased expression of ACHE protein]
ACHE protein affects the susceptibility to Acetylcysteine
Acetylcysteine inhibits the reaction [Chlorpyrifos results in increased expression of ACHE mRNA alternative form]; Acetylcysteine inhibits the reaction [Streptozocin results in increased activity of ACHE protein]

PMID:20399762 PMID:20688495 PMID:26769589 PMID:27087133 PMID:27163631 More...

NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651

G

acid phosphatase 3

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of ACP3 mRNA

NCBI chr 8:104,905,570...104,956,146
Ensembl chr 8:104,905,586...104,954,236

G

acyl-CoA synthetase medium-chain family member 5

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of ACSM5 mRNA; Acetylcysteine inhibits the reaction [[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of ACSM5 mRNA]

NCBI chr 1:173,870,873...173,896,838
Ensembl chr 1:173,863,041...173,898,588

G

acyl-CoA synthetase short-chain family member 1

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of ACSS1 mRNA

NCBI chr 3:139,450,383...139,500,325
Ensembl chr 3:139,450,383...139,500,325

G

actin alpha 2, smooth muscle

multiple interactions

Acetylcysteine inhibits the reaction [27-hydroxycholesterol results in increased expression of ACTA2 protein]; Acetylcysteine inhibits the reaction [TGFB1 protein results in increased expression of ACTA2 protein]
Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of ACTA2 mRNA]
Acetylcysteine inhibits the reaction [[bisphenol A co-treated with Dietary Fats co-treated with Cholesterol co-treated with Cholic Acid] results in increased expression of ACTA2 protein]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased expression of ACTA2 protein]; Acetylcysteine inhibits the reaction [sodium arsenite results in increased expression of ACTA2 protein]

PMID:16757516 PMID:21134390 PMID:32659284 PMID:33131013 PMID:35622622 More...

NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554

G

ADAM metallopeptidase domain 33

multiple interactions

Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of ADAM33 mRNA]

NCBI chr 3:118,262,395...118,283,456
Ensembl chr 3:118,271,029...118,283,461

G

adhesion G protein-coupled receptor B2

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of ADGRB2 mRNA

NCBI chr 5:142,299,190...142,362,540
Ensembl chr 5:142,331,329...142,362,540

G

adhesion G protein-coupled receptor B3

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of ADGRB3 mRNA

NCBI chr 9:27,421,168...28,148,979
Ensembl chr 9:27,421,168...28,148,855

G

alcohol dehydrogenase 1C (class I), gamma polypeptide

multiple interactions

Acetylcysteine inhibits the reaction [Ethanol results in increased expression of ADH1 mRNA]

NCBI chr 2:226,797,303...226,808,892
Ensembl chr 2:226,797,303...226,808,892

G

adiponectin, C1Q and collagen domain containing

multiple interactions

Acetylcysteine inhibits the reaction [Palmitates results in decreased expression of ADIPOQ mRNA]; Acetylcysteine inhibits the reaction [Palmitates results in decreased expression of ADIPOQ protein]; Acetylcysteine inhibits the reaction [Streptozocin results in decreased expression of ADIPOQ mRNA]; Acetylcysteine inhibits the reaction [Streptozocin results in decreased expression of ADIPOQ protein]; Allopurinol promotes the reaction [Acetylcysteine inhibits the reaction [Streptozocin results in decreased expression of ADIPOQ mRNA]]; Allopurinol promotes the reaction [Acetylcysteine inhibits the reaction [Streptozocin results in decreased expression of ADIPOQ protein]]

PMID:17471172 PMID:21912612

NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564

G

adiponectin receptor 2

multiple interactions

Acetylcysteine inhibits the reaction [Streptozocin results in decreased expression of ADIPOR2 protein]; Allopurinol promotes the reaction [Acetylcysteine inhibits the reaction [Streptozocin results in decreased expression of ADIPOR2 protein]]

NCBI chr 4:152,524,604...152,588,848
Ensembl chr 4:152,524,623...152,559,355

G

angiotensinogen

multiple interactions

Acetylcysteine inhibits the reaction [AGT protein results in increased phosphorylation of and results in increased activity of EGFR protein]
Acetylcysteine inhibits the reaction [AGT protein modified form results in increased abundance of Reactive Oxygen Species]

PMID:15849355 PMID:30703374

NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977

G

angiotensin II receptor, type 1a

multiple interactions

Acetylcysteine inhibits the reaction [sodium arsenite results in increased expression of AGTR1 mRNA]

NCBI chr17:34,173,446...34,226,892
Ensembl chr17:34,174,429...34,226,946

G

aryl hydrocarbon receptor

increases expression
multiple interactions

Acetylcysteine results in increased expression of AHR protein
Acetylcysteine inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] which results in increased expression of and affects the localization of AHR protein]; Acetylcysteine inhibits the reaction [hydroquinone results in increased expression of AHR protein]; Acetylcysteine promotes the reaction [AHR protein binds to CDKN1A enhancer]; Acetylcysteine promotes the reaction [AHR protein binds to CDKN1B enhancer]

PMID:18022818 PMID:21569840 PMID:31551408 PMID:35123993

NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568

G

allograft inflammatory factor 1

multiple interactions

Acetylcysteine inhibits the reaction [NOX4 protein promotes the reaction [[Lipopolysaccharides co-treated with IFNG1 protein] results in increased expression of AIF1 protein]]

NCBI chr20:3,646,784...3,652,670
Ensembl chr20:3,646,777...3,652,668

G

apoptosis inducing factor, mitochondria associated 1

multiple interactions

Acetylcysteine inhibits the reaction [Cadmium Chloride affects the localization of AIFM1 protein]
Acetylcysteine inhibits the reaction [bisphenol A affects the localization of AIFM1 protein]
Acetylcysteine inhibits the reaction [1,12-benzoperylene results in increased expression of AIFM1 protein]; Acetylcysteine inhibits the reaction [2'-(4-chlorophenyl)-3-(4-chlorophenylidene)-5,10-dimethyl-12-methylene-decahydro-1,2-(1',3'-dioxocyclopenta(c))azuleno(4,5-b)furan-4,11-dione affects the localization of AIFM1 protein]; Acetylcysteine inhibits the reaction [[Zinc Sulfate co-treated with prolinedithiocarbamate] affects the localization of AIFM1 protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide affects the localization of AIFM1 protein]; Acetylcysteine inhibits the reaction [perfosfamide results in increased localization of AIFM1 protein]; Acetylcysteine inhibits the reaction [Tosylphenylalanyl Chloromethyl Ketone affects the localization of AIFM1 protein]

PMID:18034189 PMID:18412143 PMID:18506790 PMID:18951928 PMID:19679660 More...

NCBI chr X:127,650,223...127,689,356
Ensembl chr X:127,650,226...127,689,256

G

aminoacyl tRNA synthetase complex-interacting multifunctional protein 1

decreases expression

Acetylcysteine results in decreased expression of AIMP1 mRNA

NCBI chr 2:221,151,907...221,175,458
Ensembl chr 2:221,151,904...221,175,728

G

aldo-keto reductase family 1, member C3

multiple interactions

Acetylcysteine inhibits the reaction [cadmium acetate results in increased expression of AKR1C3 protein]; Acetylcysteine inhibits the reaction [SOD2 protein affects the expression of AKR1C3 mRNA]

PMID:18829485 PMID:21787718

NCBI chr17:66,110,970...66,127,867
Ensembl chr17:66,110,963...66,127,873

G

AKT serine/threonine kinase 1

multiple interactions

2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Acetylcysteine results in increased activity of and results in increased phosphorylation of AKT1 protein]; [Acetylcysteine co-treated with Hydrogen Peroxide] results in increased phosphorylation of AKT1 protein; Acetylcysteine inhibits the reaction [1,4-naphthoquinone analog results in decreased phosphorylation of AKT1 protein]; Acetylcysteine inhibits the reaction [Arsenic analog results in increased phosphorylation of and affects the localization of AKT1 protein]; Acetylcysteine inhibits the reaction [arsenic trichloride results in increased phosphorylation of AKT1 protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in decreased activity of AKT1 protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in decreased phosphorylation of AKT1 protein]; Acetylcysteine inhibits the reaction [butein results in decreased phosphorylation of AKT1 protein]; Acetylcysteine inhibits the reaction [Butyric Acid results in decreased phosphorylation of AKT1 protein]; Acetylcysteine inhibits the reaction [cadmium acetate results in increased phosphorylation of AKT1 protein]; Acetylcysteine inhibits the reaction [Cadmium results in increased phosphorylation of AKT1 protein]; Acetylcysteine inhibits the reaction [Cannabidiol results in decreased phosphorylation of AKT1 protein]; Acetylcysteine inhibits the reaction [cholix toxin, Vibrio cholerae results in increased phosphorylation of AKT1 protein]; Acetylcysteine inhibits the reaction [cucurbitacin E affects the phosphorylation of AKT1 protein]; Acetylcysteine inhibits the reaction [cyadox results in increased phosphorylation of AKT1 protein]; Acetylcysteine inhibits the reaction [Daunorubicin results in decreased phosphorylation of AKT1 protein]; Acetylcysteine inhibits the reaction [diallyl trisulfide results in increased phosphorylation of AKT1 protein]; Acetylcysteine inhibits the reaction [divinyl sulfone analog results in decreased phosphorylation of AKT1 protein]; Acetylcysteine inhibits the reaction [Estradiol results in increased phosphorylation of AKT1 protein]; Acetylcysteine inhibits the reaction [Fingolimod Hydrochloride results in decreased phosphorylation of AKT1 protein]; Acetylcysteine inhibits the reaction [ginsenoside Rk1 results in decreased phosphorylation of AKT1 protein]; Acetylcysteine inhibits the reaction [hydroquinone results in decreased phosphorylation of AKT1 protein]; Acetylcysteine inhibits the reaction [Morpholines analog results in decreased phosphorylation of AKT1 protein]; Acetylcysteine inhibits the reaction [morusin results in decreased phosphorylation of AKT1 protein]; Acetylcysteine inhibits the reaction [N-arachidonoylalanine results in decreased phosphorylation of AKT1 protein]; Acetylcysteine inhibits the reaction [oenothein B results in decreased phosphorylation of AKT1 protein]; Acetylcysteine inhibits the reaction [Oligopeptides analog results in decreased phosphorylation of AKT1 protein]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased phosphorylation of AKT1 protein]; Acetylcysteine inhibits the reaction [Patulin results in decreased phosphorylation of AKT1 protein]; Acetylcysteine inhibits the reaction [sodium arsenite results in increased phosphorylation of AKT1 protein]; Acetylcysteine inhibits the reaction [synaptamide results in decreased phosphorylation of AKT1 protein]; Acetylcysteine inhibits the reaction [titanium dioxide results in increased phosphorylation of AKT1 protein]; Acetylcysteine inhibits the reaction [tubocapsenolide A results in increased degradation of AKT1 protein]; Acetylcysteine inhibits the reaction [Vehicle Emissions results in increased phosphorylation of AKT1 protein]; Acetylcysteine results in increased activity of and results in increased phosphorylation of AKT1 protein
Acetylcysteine inhibits the reaction [4-nonylphenol results in decreased phosphorylation of AKT1 protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of AKT1 protein]; Acetylcysteine inhibits the reaction [Cadmium results in increased phosphorylation of AKT1 protein]; Acetylcysteine inhibits the reaction [Glucose results in decreased phosphorylation of AKT1 protein]; Acetylcysteine inhibits the reaction [Glucose results in increased phosphorylation of AKT1 protein]; Acetylcysteine inhibits the reaction [Zinc results in increased phosphorylation of AKT1 protein]
Acetylcysteine inhibits the reaction [cadmium acetate results in decreased expression of AKT1 protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of AKT1 protein]; Acetylcysteine inhibits the reaction [Cadmium results in increased phosphorylation of AKT1 protein]; Acetylcysteine inhibits the reaction [Endosulfan results in increased phosphorylation of AKT1 protein]; Acetylcysteine inhibits the reaction [INS1 protein results in increased phosphorylation of AKT1 protein]; Acetylcysteine inhibits the reaction [Mercuric Chloride results in increased phosphorylation of AKT1 protein]; Acetylcysteine inhibits the reaction [Methylmercury Compounds results in increased phosphorylation of AKT1 protein]; Acetylcysteine inhibits the reaction [Tobacco Smoke Pollution results in increased expression of AKT1 mRNA]

PMID:12168106 PMID:12614848 PMID:16137721 PMID:16731823 PMID:18442981 More...

NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921

G

aminolevulinate dehydratase

multiple interactions

Acetylcysteine promotes the reaction [Zinc Sulfate inhibits the reaction [sodium arsenite results in decreased activity of ALAD protein]]

NCBI chr 5:75,961,993...75,972,334
Ensembl chr 5:75,961,993...75,972,474

G

albumin

multiple interactions
affects binding

Acetylcysteine inhibits the reaction [Acetaminophen results in decreased expression of ALB protein]; Acetylcysteine inhibits the reaction [ALB protein modified form results in decreased expression of MFN2 protein]; Acetylcysteine inhibits the reaction [ALB protein modified form results in increased abundance of Hydrogen Peroxide]; Acetylcysteine inhibits the reaction [Mercuric Chloride results in decreased expression of ALB protein]; Acetylcysteine inhibits the reaction [Mustard Gas results in increased expression of ALB protein]; Acetylcysteine promotes the reaction [Selenium inhibits the reaction [Mercuric Chloride results in decreased expression of ALB protein]]; Selenium promotes the reaction [Acetylcysteine inhibits the reaction [Mercuric Chloride results in decreased expression of ALB protein]]
N-acetyl-L-cysteine binds Alb protein in serum

CTD
RGD

PMID:11428623 PMID:20804811 PMID:24485406 PMID:27997345 PMID:12458670

NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836

G

aldehyde dehydrogenase 2 family member

multiple interactions

Acetylcysteine inhibits the reaction [Nitroglycerin results in decreased activity of ALDH2 protein]

NCBI chr12:34,949,549...34,982,527
Ensembl chr12:34,901,219...34,982,521

G

ALK receptor tyrosine kinase

multiple interactions

Acetylcysteine affects the phosphorylation of and affects the activity of ALK protein mutant form

NCBI chr 6:22,879,653...23,599,636
Ensembl chr 6:22,880,625...23,598,034

G

alkB homolog 5, RNA demethylase

multiple interactions

Acetylcysteine inhibits the reaction [sodium arsenite results in increased expression of ALKBH5 mRNA]
Acetylcysteine inhibits the reaction [Paraquat results in decreased expression of ALKBH5 mRNA]

PMID:31004932 PMID:34425375

NCBI chr10:45,344,888...45,366,331
Ensembl chr10:45,343,395...45,366,331

G

alkaline phosphatase, biomineralization associated

multiple interactions

Acetylcysteine inhibits the reaction [[Aluminum Chloride results in increased abundance of Aluminum] which results in decreased expression of ALPL mRNA]

NCBI chr 5:149,951,397...150,006,424
Ensembl chr 5:149,951,409...150,006,446

G

alpha-methylacyl-CoA racemase

multiple interactions

Acetylcysteine inhibits the reaction [SOD2 protein affects the expression of AMACR mRNA]

NCBI chr 2:59,946,158...59,958,255
Ensembl chr 2:59,946,153...59,958,255

G

angiogenin

multiple interactions

Acetylcysteine inhibits the reaction [Cadmium Chloride results in decreased secretion of ANG protein]

NCBI chr15:24,312,711...24,323,361

G

angiopoietin 1

decreases secretion

Acetylcysteine results in decreased secretion of ANGPT1 protein

NCBI chr 7:73,528,345...73,783,953
Ensembl chr 7:73,531,486...73,784,067

G

angiopoietin-like 4

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of ANGPTL4 mRNA

NCBI chr 7:14,550,288...14,557,797
Ensembl chr 7:14,550,311...14,556,519

G

ankyrin repeat domain 29

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of ANKRD29 mRNA

NCBI chr18:3,436,301...3,494,292
Ensembl chr18:3,436,303...3,494,296

G

annexin A5

multiple interactions

Acetylcysteine inhibits the reaction [Sodium Fluoride results in increased expression of ANXA5 protein]; Acetylcysteine inhibits the reaction [Tin Fluorides results in increased expression of ANXA5 protein]

NCBI chr 2:119,314,007...119,344,703
Ensembl chr 2:119,314,007...119,353,369

G

amine oxidase, copper containing 1

multiple interactions

Acetylcysteine inhibits the reaction [Methotrexate results in increased activity of AOC1 protein]

NCBI chr 4:77,812,260...77,831,846
Ensembl chr 4:77,812,260...77,831,840

G

apoptotic peptidase activating factor 1

multiple interactions

Acetylcysteine inhibits the reaction [Cholesterol analog results in increased expression of APAF1 mRNA]; Acetylcysteine inhibits the reaction [tert-Butylhydroperoxide results in increased expression of APAF1 protein]
Acetylcysteine inhibits the reaction [Methylmercury Compounds results in increased expression of APAF1 protein]

PMID:15877105 PMID:19477266 PMID:35396826

NCBI chr 7:25,494,143...25,579,540
Ensembl chr 7:25,494,609...25,579,540

G

apurinic/apyrimidinic endodeoxyribonuclease 1

multiple interactions

Acetylcysteine inhibits the reaction [Hypochlorous Acid results in increased expression of APEX1 protein]
Acetylcysteine inhibits the reaction [sodium arsenite results in increased expression of APEX1 mRNA]

PMID:12231548 PMID:17938202

NCBI chr15:24,144,595...24,146,785
Ensembl chr15:24,144,362...24,146,785

G

apurinic/apyrimidinic endodeoxyribonuclease 2

multiple interactions
decreases expression

Acetylcysteine inhibits the reaction [Acrylonitrile results in increased expression of APEX2 mRNA]
Acetylcysteine results in decreased expression of APEX2 mRNA

NCBI chr X:19,425,684...19,508,459
Ensembl chr X:19,487,419...19,508,439

G

aph-1 homolog B, gamma secretase subunit

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of APH1B mRNA

NCBI chr 8:67,429,198...67,454,735
Ensembl chr 8:67,429,198...67,450,243

G

apolipoprotein E

increases expression
multiple interactions

Acetylcysteine results in increased expression of APOE mRNA
Acetylcysteine inhibits the reaction [[[Cadmium Chloride results in increased abundance of Cadmium] which co-treated with hydroquinone] results in decreased expression of APOE mRNA]; Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of APOE mRNA]; Acetylcysteine inhibits the reaction [hydroquinone results in decreased expression of APOE mRNA]

NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932

G

amyloid beta precursor protein

multiple interactions

Acetylcysteine inhibits the reaction [APP protein affects the localization of RELA protein]; Acetylcysteine inhibits the reaction [APP protein results in increased activity of MAPK14 protein]; Acetylcysteine inhibits the reaction [APP protein results in increased activity of MAPK8 protein]; Acetylcysteine inhibits the reaction [APP protein results in increased expression of and results in increased cleavage of CASP1 protein]; Acetylcysteine inhibits the reaction [APP protein results in increased expression of and results in increased cleavage of IL1B protein]; Acetylcysteine inhibits the reaction [APP protein results in increased expression of NLRP3 protein]

PMID:12684028 PMID:28004443

NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561

G

aquaporin 2

increases expression

Acetylcysteine results in increased expression of AQP2 protein

NCBI chr 7:130,711,433...130,716,468
Ensembl chr 7:130,711,413...130,716,468

G

androgen receptor

multiple interactions

Acetylcysteine inhibits the reaction [SOD2 protein affects the activity of AR protein]; Acetylcysteine inhibits the reaction [Sodium Selenite results in decreased expression of AR mRNA]; Acetylcysteine inhibits the reaction [Sodium Selenite results in decreased expression of AR protein]

PMID:16928829 PMID:18829485

NCBI chr X:63,104,771...63,273,934
Ensembl chr X:63,104,771...63,273,925

G

ADP ribosylation factor like GTPase 13A

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of ARL13A mRNA

NCBI chr X:97,380,370...97,406,704
Ensembl chr X:97,380,390...97,406,702

G

aryl hydrocarbon receptor nuclear translocator

multiple interactions

Acetylcysteine inhibits the reaction [Curcumin results in increased degradation of ARNT protein]

NCBI chr 2:182,997,731...183,056,584
Ensembl chr 2:182,997,736...183,056,580

G

arrestin domain containing 3

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of ARRDC3 mRNA

NCBI chr 2:11,137,464...11,149,978
Ensembl chr 2:11,137,460...11,149,978

G

ADP-ribosyltransferase 4

decreases expression

Acetylcysteine results in decreased expression of ART4 mRNA

NCBI chr 4:169,740,331...169,751,571
Ensembl chr 4:169,740,331...169,750,665

G

asparagine synthetase (glutamine-hydrolyzing)

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of ASNS mRNA

NCBI chr 4:35,784,995...35,803,474
Ensembl chr 4:35,785,237...35,803,423

G

astacin like metalloendopeptidase

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of ASTL mRNA

NCBI chr 3:114,563,135...114,580,295
Ensembl chr 3:114,563,135...114,578,868

G

activating transcription factor 2

multiple interactions

Acetylcysteine inhibits the reaction [chromium hexavalent ion results in increased phosphorylation of ATF2 protein]
Acetylcysteine inhibits the reaction [2-aminodiphenyl results in increased phosphorylation of ATF2 protein]

PMID:19654923 PMID:22288910

NCBI chr 3:58,718,323...58,795,280
Ensembl chr 3:58,718,332...58,795,236

G

activating transcription factor 3

multiple interactions

Acetylcysteine inhibits the reaction [Acrylamide results in increased expression of and affects the localization of ATF3 protein]

NCBI chr13:102,751,278...102,800,520
Ensembl chr13:102,751,321...102,764,631

G

activating transcription factor 4

multiple interactions
decreases expression
increases expression

Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of ATF4 protein]; Acetylcysteine inhibits the reaction [Acrylamide results in increased expression of ATF4 protein]; Acetylcysteine inhibits the reaction [fangchinoline results in increased expression of ATF4 protein]; Acetylcysteine inhibits the reaction [scutebarbatine A results in increased expression of ATF4 protein]; Acetylcysteine inhibits the reaction [sodium arsenite results in increased expression of ATF4 protein]; Acetylcysteine inhibits the reaction [Tobacco Smoke Pollution analog results in increased expression of ATF4 protein]; Acetylcysteine inhibits the reaction [tris(1,3-dichloro-2-propyl)phosphate results in increased expression of ATF4 protein]; Acetylcysteine inhibits the reaction [withaferin A results in increased expression of ATF4 protein]
[Acetylcysteine co-treated with Trichloroethylene] results in increased expression of ATF4 mRNA; Acetylcysteine inhibits the reaction [4-hydroxy-2-nonenal results in increased expression of ATF4 protein]; Acetylcysteine inhibits the reaction [tetrachlorobenzoquinone results in increased expression of ATF4 protein]
Acetylcysteine results in decreased expression of ATF4 protein
Acetylcysteine inhibits the reaction [chloroacetic acid results in increased expression of ATF4 protein]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased expression of ATF4 mRNA]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased expression of ATF4 protein]; Acetylcysteine inhibits the reaction [methylmercuric chloride results in increased expression of ATF4 protein]; Acetylcysteine promotes the reaction [perfluorooctanoic acid results in increased expression of ATF4 mRNA]
Acetylcysteine results in increased expression of ATF4 protein

PMID:15788408 PMID:19722195 PMID:21266191 PMID:24291486 PMID:25451595 More...

NCBI chr 7:111,804,135...111,806,457
Ensembl chr 7:111,804,183...111,806,446

G

activating transcription factor 6

multiple interactions

Acetylcysteine inhibits the reaction [hydroquinone results in decreased expression of ATF6 protein]; Acetylcysteine inhibits the reaction [Sodium Selenite results in increased expression of ATF6 protein]; Acetylcysteine results in increased metabolism of and results in increased activity of ATF6 protein
Acetylcysteine inhibits the reaction [4-hydroxy-2-nonenal results in increased expression of ATF6 protein modified form]; Acetylcysteine inhibits the reaction [arsenite results in increased expression of ATF6 protein]; Acetylcysteine inhibits the reaction [gadolinium chloride results in increased expression of ATF6 protein]
Acetylcysteine inhibits the reaction [chloroacetic acid results in increased cleavage of ATF6 protein]; Acetylcysteine inhibits the reaction [methylmercuric chloride results in increased cleavage of ATF6 protein]; Acetylcysteine inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of ATF6 protein]; Acetylcysteine inhibits the reaction [sodium arsenite results in increased expression of ATF6 protein]

PMID:18077580 PMID:19722195 PMID:21198628 PMID:21911445 PMID:24291486 More...

NCBI chr13:82,927,579...83,106,381
Ensembl chr13:82,930,034...83,107,177

G

autophagy related 10

multiple interactions

Acetylcysteine inhibits the reaction [Zinc Oxide analog results in increased expression of ATG10 mRNA]

NCBI chr 2:22,109,304...22,398,313
Ensembl chr 2:22,108,426...22,398,233

G

autophagy related 12

multiple interactions

Acetylcysteine inhibits the reaction [Acrolein results in increased expression of ATG12 protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of ATG12 mRNA]; Acetylcysteine inhibits the reaction [bisphenol A results in increased expression of ATG12 mRNA]; Acetylcysteine inhibits the reaction [Tobacco Smoke Pollution results in increased expression of ATG12 mRNA]; Acetylcysteine inhibits the reaction [Vorinostat promotes the reaction [ATG5 protein binds to ATG12 protein]]
Acetylcysteine inhibits the reaction [Zinc Oxide analog results in increased expression of ATG12 mRNA]

PMID:20543569 PMID:24614525 PMID:29307831 PMID:30205151 PMID:33146789 More...

NCBI chr18:39,452,247...39,462,424
Ensembl chr18:39,452,191...39,462,418

G

autophagy related 14

multiple interactions

Acetylcysteine inhibits the reaction [bisphenol A results in increased expression of ATG14 mRNA]

NCBI chr15:20,795,750...20,827,113
Ensembl chr15:20,795,750...20,827,113

G

autophagy related 16-like 1

multiple interactions

Acetylcysteine inhibits the reaction [Acrolein results in increased expression of ATG16L1 protein]

NCBI chr 9:88,420,737...88,457,530
Ensembl chr 9:88,422,038...88,457,529

G

autophagy related 16-like 2

multiple interactions

Acetylcysteine inhibits the reaction [Tobacco Smoke Pollution results in increased expression of ATG16L2 mRNA]

NCBI chr 1:155,687,386...155,703,419
Ensembl chr 1:155,684,564...155,703,420

G

autophagy related 4A, cysteine peptidase

multiple interactions

Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of ATG4A protein]

NCBI chr X:104,665,345...104,765,271
Ensembl chr X:104,665,345...104,765,268

G

autophagy related 4C, cysteine peptidase

multiple interactions

Acetylcysteine inhibits the reaction [Paraquat results in decreased expression of ATG4C mRNA]

NCBI chr 5:113,867,218...113,935,534
Ensembl chr 5:113,867,092...113,934,830

G

autophagy related 5

multiple interactions

Acetylcysteine inhibits the reaction [Acrolein results in increased expression of ATG5 protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of ATG5 mRNA]; Acetylcysteine inhibits the reaction [Butyric Acid results in increased expression of ATG5 protein]; Acetylcysteine inhibits the reaction [Tobacco Smoke Pollution results in increased expression of ATG5 mRNA]; Acetylcysteine inhibits the reaction [Vorinostat promotes the reaction [ATG5 protein binds to ATG12 protein]]
Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of ATG5 mRNA]; Acetylcysteine inhibits the reaction [Zinc Oxide analog results in increased expression of ATG5 mRNA]

PMID:20543569 PMID:24614525 PMID:28600122 PMID:29307831 PMID:30205151 More...

NCBI chr20:47,798,217...47,889,216
Ensembl chr20:47,798,290...47,889,209

G

autophagy related 7

multiple interactions

Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of ATG7 mRNA]; Acetylcysteine inhibits the reaction [Acrolein results in increased expression of ATG7 protein]; Acetylcysteine inhibits the reaction [Apigenin results in increased expression of ATG7 protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of ATG7 mRNA]

PMID:29247770 PMID:29307831 PMID:30205151 PMID:31319114 PMID:33462182

NCBI chr 4:147,718,663...147,925,656
Ensembl chr 4:147,718,752...147,925,593

G

ATM serine/threonine kinase

multiple interactions
increases phosphorylation

Acetylcysteine inhibits the reaction [2,3,5-trichloro-6-phenyl-(1,4)benzoquinone results in increased expression of ATM protein]; Acetylcysteine inhibits the reaction [Aristolochic Acids results in increased expression of ATM protein modified form]; Acetylcysteine inhibits the reaction [ATM protein promotes the reaction [Doxorubicin results in increased activity of TP53 protein]]; Acetylcysteine inhibits the reaction [dorsomorphin results in increased phosphorylation of ATM protein]; Acetylcysteine inhibits the reaction [Doxorubicin promotes the reaction [ATM protein results in increased phosphorylation of CHEK1 protein]]; Acetylcysteine inhibits the reaction [Doxorubicin promotes the reaction [ATM protein results in increased phosphorylation of CHEK2 protein]]; Acetylcysteine inhibits the reaction [Doxorubicin promotes the reaction [ATM protein results in increased phosphorylation of NBN protein]]; Acetylcysteine inhibits the reaction [Doxorubicin promotes the reaction [ATM protein results in increased phosphorylation of SMC1A protein]]; Acetylcysteine inhibits the reaction [Doxorubicin promotes the reaction [ATM protein results in increased phosphorylation of TP53 protein]]; Acetylcysteine inhibits the reaction [Doxorubicin results in increased phosphorylation of ATM protein]; Acetylcysteine inhibits the reaction [polyhexamethyleneguanidine results in increased phosphorylation of ATM protein]; Acetylcysteine inhibits the reaction [usnic acid results in increased phosphorylation of ATM protein]
Acetylcysteine affects the reaction [yttrium chloride affects the expression of ATM protein]
Acetylcysteine inhibits the reaction [2-chloroethyl ethyl sulfide results in increased expression of ATM protein]
Acetylcysteine results in increased phosphorylation of ATM protein

PMID:15489221 PMID:23274516 PMID:24792323 PMID:26451628 PMID:31168028 More...

NCBI chr 8:53,828,741...53,932,773
Ensembl chr 8:53,831,093...53,932,437

G

antioxidant 1 copper chaperone

multiple interactions

Acetylcysteine inhibits the reaction [bisphenol A results in increased expression of ATOX1 mRNA]

NCBI chr10:39,564,855...39,579,892
Ensembl chr10:39,564,857...39,579,950

G

ATPase Na+/K+ transporting subunit alpha 1

multiple interactions

Acetylcysteine inhibits the reaction [Cadmium Chloride results in decreased expression of ATP1A1 protein]

NCBI chr 2:189,020,722...189,048,826
Ensembl chr 2:189,020,722...189,048,837

G

ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2

increases expression
multiple interactions

Acetylcysteine results in increased expression of ATP2A2 mRNA
Acetylcysteine inhibits the reaction [bisphenol A results in increased expression of ATP2A2 mRNA]
Acetylcysteine inhibits the reaction [Doxorubicin results in decreased expression of ATP2A2 mRNA]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in decreased expression of ATP2A2 protein]

PMID:10625299 PMID:16084531 PMID:17005195 PMID:36315628

NCBI chr12:34,072,710...34,122,142
Ensembl chr12:34,072,683...34,122,101

G

ATP synthase F1 subunit alpha

multiple interactions

Acetylcysteine inhibits the reaction [Cadmium Chloride results in decreased expression of ATP5F1A mRNA]

NCBI chr18:71,292,406...71,300,342
Ensembl chr18:71,292,374...71,300,794

G

ATPase H+ transporting V0 subunit D1

multiple interactions

Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of ATP6V0D1 mRNA]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of ATP6V0D1 mRNA]

PMID:29307831 PMID:31319114

NCBI chr19:33,403,352...33,447,357
Ensembl chr19:33,403,355...33,447,450

G

ATPase H+ transporting V0 subunit D2

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of ATP6V0D2 mRNA
[Acetylcysteine co-treated with CSF1R protein co-treated with TNFSF11 protein] results in decreased expression of ATP6V0D2 mRNA; Acetylcysteine affects the reaction [[NFE2L2 protein affects the susceptibility to sodium arsenite] affects the reaction [[CSF1R protein co-treated with TNFSF11 protein] affects the expression of ATP6V0D2 mRNA]]; Acetylcysteine inhibits the reaction [[sodium arsenite co-treated with CSF1R protein co-treated with TNFSF11 protein] results in increased expression of ATP6V0D2 mRNA]

PMID:22129741 PMID:30742845

NCBI chr 5:33,336,257...33,385,354
Ensembl chr 5:33,336,264...33,385,354

G

ATR serine/threonine kinase

multiple interactions

Acetylcysteine inhibits the reaction [2,3,5-trichloro-6-phenyl-(1,4)benzoquinone results in increased expression of ATR protein]

NCBI chr 8:96,426,704...96,524,152
Ensembl chr 8:96,426,724...96,524,136

G

ataxin 1

affects localization
multiple interactions

Acetylcysteine affects the localization of ATXN1 protein mutant form
Acetylcysteine inhibits the reaction [Hydrogen Peroxide affects the localization of ATXN1 protein mutant form]; Acetylcysteine inhibits the reaction [tert-Butylhydroperoxide affects the localization of ATXN1 protein mutant form]

NCBI chr17:18,737,491...19,142,360
Ensembl chr17:18,737,533...19,142,360

G

aurora kinase B

multiple interactions

Acetylcysteine inhibits the reaction [Hydrogen Peroxide affects the localization of AURKB protein]

NCBI chr10:53,744,290...53,750,831
Ensembl chr10:53,745,142...53,750,837

G

beta-2 microglobulin

decreases response to substance
multiple interactions

Acetylcysteine results in decreased susceptibility to B2M protein modified form
Acetylcysteine inhibits the reaction [B2M protein modified form results in increased abundance of Reactive Oxygen Species]

NCBI chr 3:109,095,740...109,101,764
Ensembl chr 3:109,095,729...109,101,766

G

Beta-1,3-galactosyltransferase 5

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of B3GALT5 mRNA

NCBI chr11:35,584,273...35,630,922
Ensembl chr11:35,585,220...35,630,917

G

UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 9

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of B3GNT9 mRNA

NCBI chr19:33,129,740...33,134,048
Ensembl chr19:33,128,142...33,132,344

G

BTB domain and CNC homolog 1

multiple interactions

Acetylcysteine inhibits the reaction [arsenic trioxide affects the localization of BACH1 protein]

NCBI chr11:26,939,429...26,974,876
Ensembl chr11:26,939,480...26,972,447

G

BCL2-associated agonist of cell death

multiple interactions
increases expression

Acetylcysteine inhibits the reaction [cordycepin results in increased expression of BAD protein]; Acetylcysteine inhibits the reaction [nickel acetate results in increased expression of BAD protein]
Acetylcysteine results in increased expression of BAD mRNA

PMID:21310227 PMID:22245127 PMID:26332274

NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823

G

BAG cochaperone 3

multiple interactions

Acetylcysteine inhibits the reaction [elesclomol results in increased expression of BAG3 mRNA]

NCBI chr 1:183,103,038...183,126,862
Ensembl chr 1:183,102,871...183,126,858

G

BCL2-antagonist/killer 1

multiple interactions

Acetylcysteine inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased expression of BAK1 mRNA]; Acetylcysteine inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased expression of BAK1 protein]; Acetylcysteine inhibits the reaction [nickel sulfate results in increased expression of BAK1 mRNA]; Acetylcysteine inhibits the reaction [nickel sulfate results in increased expression of BAK1 protein]
Acetylcysteine inhibits the reaction [Cadmium results in increased expression of BAK1]
Acetylcysteine inhibits the reaction [arsenic trioxide results in increased expression of BAK1 mRNA]; Acetylcysteine inhibits the reaction [Methylmercury Compounds results in increased expression of BAK1 mRNA]

PMID:21533816 PMID:21549813 PMID:22085843 PMID:23339468 PMID:28296042

NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264

G

BARX homeobox 2

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of BARX2 mRNA

NCBI chr 8:30,251,132...30,319,105
Ensembl chr 8:30,251,132...30,319,013

G

BCL2 associated X, apoptosis regulator

multiple interactions
increases expression
decreases expression

Acetylcysteine inhibits the reaction [1,3-dichloro-2-propanol results in increased expression of BAX protein]; Acetylcysteine inhibits the reaction [[Aluminum Chloride results in increased abundance of Aluminum] which results in increased expression of BAX mRNA]; Acetylcysteine inhibits the reaction [[Aluminum Chloride results in increased abundance of Aluminum] which results in increased expression of BAX protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of BAX mRNA]; Acetylcysteine inhibits the reaction [bisphenol A results in increased activity of BAX protein]; Acetylcysteine inhibits the reaction [bisphenol A results in increased expression of BAX mRNA]; Acetylcysteine inhibits the reaction [Cisplatin results in increased expression of BAX protein]; Acetylcysteine inhibits the reaction [ginsenoside Re inhibits the reaction [3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester results in increased expression of BAX protein]]; Acetylcysteine inhibits the reaction [Methylmercury Compounds results in increased expression of BAX mRNA]; Acetylcysteine inhibits the reaction [Paraquat results in increased expression of BAX protein]; Acetylcysteine inhibits the reaction [salubrinal promotes the reaction [Cisplatin results in increased expression of BAX protein]]
N-acetyl-L-cysteine inhibits the reaction [apigenin-7-O-gentiobioside increases expression of BAX protein in the stomach)
Acetylcysteine affects the reaction [lead acetate results in increased expression of BAX protein]; Acetylcysteine inhibits the reaction [4-nonylphenol results in increased expression of BAX protein]; Acetylcysteine inhibits the reaction [7-ketocholesterol results in increased expression of BAX protein]; Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of BAX protein]; Acetylcysteine inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased expression of BAX mRNA]; Acetylcysteine inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased expression of BAX protein]; Acetylcysteine inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of BAX mRNA]; Acetylcysteine inhibits the reaction [bisphenol A results in increased expression of BAX protein]; Acetylcysteine inhibits the reaction [Doxorubicin results in increased expression of BAX protein]; Acetylcysteine inhibits the reaction [Fenitrothion results in increased expression of BAX mRNA]; Acetylcysteine inhibits the reaction [Glyphosate results in increased expression of BAX mRNA]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide affects the localization of BAX protein]; Acetylcysteine inhibits the reaction [Potassium Dichromate results in increased expression of BAX mRNA]
Acetylcysteine results in increased expression of BAX mRNA
Acetylcysteine results in decreased expression of BAX protein
4-phenylbutyric acid promotes the reaction [Acetylcysteine inhibits the reaction [tris(1,3-dichloro-2-propyl)phosphate results in increased expression of BAX protein]]; Acetylcysteine inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased expression of BAX protein]; Acetylcysteine inhibits the reaction [3-oxo-29-noroleana-1,9(11),12-trien-2,20-dicarbonitrile results in increased expression of BAX protein]; Acetylcysteine inhibits the reaction [[Arsenic Trioxide co-treated with phytosphingosine] results in increased localization of BAX protein]; Acetylcysteine inhibits the reaction [[Berberine co-treated with Cisplatin] results in increased expression of BAX protein]; Acetylcysteine inhibits the reaction [[Cadmium Chloride co-treated with Buthionine Sulfoximine] results in decreased expression of BAX protein]; Acetylcysteine inhibits the reaction [Acetaminophen results in increased expression of BAX mRNA]; Acetylcysteine inhibits the reaction [Acrylonitrile results in increased expression of BAX protein]; Acetylcysteine inhibits the reaction [Antimycin A results in increased expression of BAX mRNA]; Acetylcysteine inhibits the reaction [Arsenic Trioxide affects the localization of BAX protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of BAX protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased localization of BAX protein]; Acetylcysteine inhibits the reaction [cadmium acetate results in increased cleavage of BAX protein]; Acetylcysteine inhibits the reaction [chromium tripicolinate results in increased expression of BAX protein]; Acetylcysteine inhibits the reaction [Cisplatin results in increased expression of and results in increased activity of BAX protein]; Acetylcysteine inhibits the reaction [Cisplatin results in increased expression of BAX protein]; Acetylcysteine inhibits the reaction [cordycepin results in increased expression of BAX protein]; Acetylcysteine inhibits the reaction [cypermethrin results in increased expression of BAX mRNA]; Acetylcysteine inhibits the reaction [Doxorubicin results in increased expression of BAX protein]; Acetylcysteine inhibits the reaction [Fenbendazole analog results in increased expression of BAX protein]; Acetylcysteine inhibits the reaction [Fenbendazole results in increased expression of BAX protein]; Acetylcysteine inhibits the reaction [gingerol results in increased expression of BAX protein]; Acetylcysteine inhibits the reaction [ginsenoside Rk1 results in increased expression of BAX protein]; Acetylcysteine inhibits the reaction [glabridin results in increased expression of BAX protein]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased expression of BAX protein]; Acetylcysteine inhibits the reaction [hydroquinone results in increased expression of BAX protein]; Acetylcysteine inhibits the reaction [Malathion results in increased expression of BAX protein]; Acetylcysteine inhibits the reaction [nickel acetate results in increased expression of BAX protein]; Acetylcysteine inhibits the reaction [Paraquat results in increased expression of BAX mRNA]; Acetylcysteine inhibits the reaction [perfosfamide affects the folding of BAX protein]; Acetylcysteine inhibits the reaction [perfosfamide results in increased localization of BAX]; Acetylcysteine inhibits the reaction [Polystyrenes analog results in increased expression of BAX protein]; Acetylcysteine inhibits the reaction [Propofol results in increased expression of BAX protein]; Acetylcysteine inhibits the reaction [Resveratrol promotes the reaction [Arsenic Trioxide results in increased expression of BAX protein]]; Acetylcysteine inhibits the reaction [surfactin peptide results in increased expression of BAX protein]; Acetylcysteine inhibits the reaction [tert-butyl-2-(4,5-dihydrogen-4,4,5,5-tetramethyl-3-O-1H-imidazole-3-cationic-1-oxyl-2-pyrrolidine-1-carboxylic ester) affects the expression of BAX protein]; Acetylcysteine inhibits the reaction [TNFSF10 protein results in increased expression of BAX protein]; Acetylcysteine inhibits the reaction [tomentosin results in increased expression of BAX protein]; Acetylcysteine inhibits the reaction [tris(1,3-dichloro-2-propyl)phosphate results in increased expression of BAX protein]; Acetylcysteine promotes the reaction [4-phenylbutyric acid inhibits the reaction [tris(1,3-dichloro-2-propyl)phosphate results in increased expression of BAX protein]]; Acetylcysteine results in decreased susceptibility to [1-(3',4',5'-trimethoxyphenyl)-3-(3'',4''-dimethoxy-2'-hydroxyphenyl)propane results in increased expression of BAX protein]
Acetylcysteine results in increased expression of BAX protein

CTD
RGD

PMID:11166918 PMID:11341981 PMID:15496615 PMID:15735709 PMID:16169029 More...

NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368

G

Bcl-2 binding component 3

multiple interactions

Acetylcysteine inhibits the reaction [4-hydroxy-2-nonenal results in increased expression of BBC3 mRNA]
Acetylcysteine inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased expression of BBC3 protein]

PMID:24291486 PMID:32540572

NCBI chr 1:77,013,281...77,022,509
Ensembl chr 1:77,014,543...77,022,509

G

brain enriched myelin associated protein 1

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of BCAS1 mRNA

NCBI chr 3:159,136,077...159,219,072
Ensembl chr 3:159,136,083...159,219,106

G

butyrylcholinesterase

multiple interactions

Acetylcysteine inhibits the reaction [Streptozocin results in increased activity of BCHE protein]
Acetylcysteine inhibits the reaction [Chlorpyrifos results in decreased activity of BCHE protein]; Acetylcysteine inhibits the reaction [chlorpyrifos-methyl results in decreased activity of BCHE protein]

PMID:27087133 PMID:34425170

NCBI chr 2:158,308,674...158,401,148
Ensembl chr 2:158,307,584...158,401,148

G

BCL2, apoptosis regulator

decreases expression
multiple interactions
decreases response to substance

Acetylcysteine results in decreased expression of BCL2 protein
N-acetyl-L-cysteine inhibits the reaction [apigenin-7-O-gentiobioside decreases expression of BCL2 protein in the stomach)
Acetylcysteine inhibits the reaction [7-ketocholesterol results in decreased expression of BCL2 protein]; Acetylcysteine inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in decreased expression of BCL2 mRNA]; Acetylcysteine inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in decreased expression of BCL2 protein]; Acetylcysteine inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of BCL2 mRNA]; Acetylcysteine inhibits the reaction [arsenite results in increased expression of BCL2 protein]; Acetylcysteine inhibits the reaction [Fenitrothion results in decreased expression of BCL2 mRNA]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in decreased expression of BCL2 protein]; Acetylcysteine inhibits the reaction [Norepinephrine results in decreased expression of BCL2 protein]; Acetylcysteine inhibits the reaction [tributyltin results in decreased expression of BCL2 protein]
4-phenylbutyric acid promotes the reaction [Acetylcysteine inhibits the reaction [tris(1,3-dichloro-2-propyl)phosphate results in decreased expression of BCL2 protein]]; [saikosaponin D co-treated with Acetylcysteine] results in decreased expression of BCL2 protein; Acetylcysteine inhibits the reaction [3-oxo-29-noroleana-1,9(11),12-trien-2,20-dicarbonitrile results in decreased expression of BCL2 protein]; Acetylcysteine inhibits the reaction [[Cadmium Chloride co-treated with Buthionine Sulfoximine] results in increased expression of BCL2 protein]; Acetylcysteine inhibits the reaction [[sodium arsenite co-treated with Vitamin K 3] results in decreased expression of BCL2 protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide promotes the reaction [Resveratrol results in decreased expression of BCL2 protein]]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in decreased expression of BCL2 protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of and affects the localization of BCL2 protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of BCL2 protein]; Acetylcysteine inhibits the reaction [Artesunate results in decreased expression of BCL2 protein]; Acetylcysteine inhibits the reaction [cordycepin results in decreased expression of BCL2 protein]; Acetylcysteine inhibits the reaction [CSC-3436 results in decreased expression of BCL2 protein]; Acetylcysteine inhibits the reaction [diallyl trisulfide results in decreased expression of BCL2 protein]; Acetylcysteine inhibits the reaction [dorsomorphin results in decreased expression of BCL2 protein]; Acetylcysteine inhibits the reaction [Doxorubicin results in decreased expression of BCL2 protein]; Acetylcysteine inhibits the reaction [gingerol results in decreased expression of BCL2 protein]; Acetylcysteine inhibits the reaction [ginsenoside Rk1 results in decreased expression of BCL2 protein]; Acetylcysteine inhibits the reaction [glabridin results in decreased expression of BCL2 protein]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in decreased expression of BCL2 protein]; Acetylcysteine inhibits the reaction [Malathion results in decreased expression of BCL2 protein]; Acetylcysteine inhibits the reaction [nickel acetate results in decreased expression of BCL2 protein]; Acetylcysteine inhibits the reaction [Paraquat results in decreased expression of BCL2 mRNA]; Acetylcysteine inhibits the reaction [perfluorooctane sulfonic acid results in decreased expression of BCL2 mRNA]; Acetylcysteine inhibits the reaction [Polystyrenes analog results in decreased expression of BCL2 protein]; Acetylcysteine inhibits the reaction [Propofol results in decreased expression of BCL2 protein]; Acetylcysteine inhibits the reaction [Resveratrol promotes the reaction [Arsenic Trioxide results in decreased expression of BCL2 protein]]; Acetylcysteine inhibits the reaction [Resveratrol results in decreased expression of BCL2 protein]; Acetylcysteine inhibits the reaction [salvin results in decreased expression of BCL2 protein]; Acetylcysteine inhibits the reaction [surfactin peptide results in decreased expression of BCL2 protein]; Acetylcysteine inhibits the reaction [tert-butyl-2-(4,5-dihydrogen-4,4,5,5-tetramethyl-3-O-1H-imidazole-3-cationic-1-oxyl-2-pyrrolidine-1-carboxylic ester) affects the expression of BCL2 protein]; Acetylcysteine inhibits the reaction [TNFSF10 protein results in decreased expression of BCL2 protein]; Acetylcysteine inhibits the reaction [tomentosin results in decreased expression of BCL2 protein]; Acetylcysteine inhibits the reaction [Tosylphenylalanyl Chloromethyl Ketone results in increased cleavage of BCL2 protein]; Acetylcysteine inhibits the reaction [tris(1,3-dichloro-2-propyl)phosphate results in decreased expression of BCL2 protein]; Acetylcysteine inhibits the reaction [Zinc deficiency results in decreased expression of BCL2 protein]; Acetylcysteine promotes the reaction [4-phenylbutyric acid inhibits the reaction [tris(1,3-dichloro-2-propyl)phosphate results in decreased expression of BCL2 protein]]; Acetylcysteine results in decreased susceptibility to [1-(3',4',5'-trimethoxyphenyl)-3-(3'',4''-dimethoxy-2'-hydroxyphenyl)propane results in decreased expression of BCL2 protein]
Acetylcysteine inhibits the reaction [1,3-dichloro-2-propanol results in decreased expression of BCL2 protein]; Acetylcysteine inhibits the reaction [3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester results in decreased expression of BCL2 protein]; Acetylcysteine inhibits the reaction [[Aluminum Chloride results in increased abundance of Aluminum] which results in decreased expression of BCL2 mRNA]; Acetylcysteine inhibits the reaction [[Aluminum Chloride results in increased abundance of Aluminum] which results in decreased expression of BCL2 protein]; Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of BCL2 mRNA]; Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of BCL2 protein]; Acetylcysteine inhibits the reaction [bisphenol A results in decreased activity of BCL2 protein]; Acetylcysteine inhibits the reaction [bisphenol A results in decreased expression of BCL2 protein]; Acetylcysteine inhibits the reaction [Cisplatin results in decreased expression of BCL2 protein]; Acetylcysteine inhibits the reaction [Methylmercury Compounds results in decreased expression of BCL2 mRNA]; Acetylcysteine inhibits the reaction [Paraquat results in decreased expression of BCL2 protein]; Acetylcysteine inhibits the reaction [salubrinal promotes the reaction [Cisplatin results in decreased expression of BCL2 protein]]
BCL2 results in decreased susceptibility to Acetylcysteine

CTD
RGD

PMID:11341981 PMID:17041759 PMID:17395010 PMID:17542780 PMID:18077580 More...

NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743

G

Bcl2-like 1

multiple interactions

Acetylcysteine inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in decreased expression of BCL2L1 protein]; Acetylcysteine inhibits the reaction [Carboplatin results in decreased expression of BCL2L1 protein]
Acetylcysteine inhibits the reaction [3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester results in decreased expression of BCL2L1 protein]
Acetylcysteine inhibits the reaction [[Sulindac co-treated with Arsenic Trioxide] results in increased phosphorylation of BCL2L1 protein]; Acetylcysteine inhibits the reaction [cordycepin results in decreased expression of BCL2L1 protein]; Acetylcysteine inhibits the reaction [dorsomorphin results in decreased expression of BCL2L1 protein]; Acetylcysteine inhibits the reaction [fucoxanthin results in decreased expression of BCL2L1 protein]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in decreased expression of BCL2L1 protein]; Acetylcysteine inhibits the reaction [nickel acetate results in decreased expression of BCL2L1 protein]; Acetylcysteine inhibits the reaction [nickel acetate results in increased expression of BCL2L1 protein]; Acetylcysteine inhibits the reaction [TNFSF10 protein results in decreased expression of BCL2L1 protein]; Acetylcysteine inhibits the reaction [tomentosin results in decreased expression of BCL2L1 protein]

PMID:18281123 PMID:18483861 PMID:20594983 PMID:21310227 PMID:22085843 More...

NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479

G

Bcl2-like 11

multiple interactions

Acetylcysteine inhibits the reaction [[Bortezomib co-treated with romidepsin] results in increased expression of BCL2L11 protein]

NCBI chr 3:115,366,783...115,404,068
Ensembl chr 3:115,366,646...115,404,068

G

BCL6, transcription repressor

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of BCL6 mRNA

NCBI chr11:76,854,090...76,877,389
Ensembl chr11:76,854,090...76,877,389

G

bradykinin receptor B1

multiple interactions

Acetylcysteine inhibits the reaction [Capsaicin results in increased expression of BDKRB1 mRNA]

NCBI chr 6:124,510,827...124,514,475
Ensembl chr 6:124,510,870...124,513,747

G

brain-derived neurotrophic factor

multiple interactions

Acetylcysteine inhibits the reaction [Oxygen deficiency results in increased secretion of BDNF protein]
Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of BDNF protein]

PMID:16553631 PMID:26138014

NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615

G

beclin 1

multiple interactions

Acetylcysteine inhibits the reaction [bisphenol A results in increased expression of BECN1 mRNA]; Acetylcysteine inhibits the reaction [brazilin results in increased expression of BECN1 protein]; Acetylcysteine inhibits the reaction [Butyric Acid results in increased expression of BECN1 protein]; Acetylcysteine inhibits the reaction [cucurbitacin E results in increased expression of and results in increased phosphorylation of BECN1 protein]; Acetylcysteine inhibits the reaction [di-n-propyldithiocarbamate results in increased expression of BECN1 protein]; Acetylcysteine inhibits the reaction [Doxorubicin results in increased expression of BECN1 protein]; Acetylcysteine inhibits the reaction [Potassium Iodide results in increased expression of BECN1 mRNA]; Acetylcysteine inhibits the reaction [Potassium Iodide results in increased expression of BECN1 protein]; Acetylcysteine inhibits the reaction [pyrovalerone analog results in increased expression of BECN1 protein]; Acetylcysteine inhibits the reaction [Tobacco Smoke Pollution results in increased expression of BECN1 mRNA]; Acetylcysteine inhibits the reaction [tris(1,3-dichloro-2-propyl)phosphate results in increased expression of BECN1 protein]; Acetylcysteine inhibits the reaction [Vorinostat results in increased expression of BECN1 protein]
Acetylcysteine inhibits the reaction [4-nonylphenol results in increased expression of BECN1 protein]; Acetylcysteine inhibits the reaction [decamethrin results in increased expression of BECN1 protein]
Acetylcysteine inhibits the reaction [[Air Pollutants, Occupational results in increased abundance of Particulate Matter] which results in increased expression of BECN1 protein]; Acetylcysteine inhibits the reaction [[CASP2 protein affects the susceptibility to Rotenone] which results in increased expression of BECN1 protein]; Acetylcysteine inhibits the reaction [chromium hexavalent ion results in increased phosphorylation of BECN1 protein]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of BECN1 protein]; Acetylcysteine inhibits the reaction [Trichloroethylene results in increased expression of BECN1 protein]; Acetylcysteine inhibits the reaction [Zinc Oxide analog results in increased expression of BECN1 protein]

PMID:20543569 PMID:21216964 PMID:24614525 PMID:26588882 PMID:26804764 More...

NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742

G

bone gamma-carboxyglutamate protein

multiple interactions

Acetylcysteine inhibits the reaction [[Aluminum Chloride results in increased abundance of Aluminum] which results in decreased expression of BGLAP mRNA]; Acetylcysteine inhibits the reaction [[Aluminum Chloride results in increased abundance of Aluminum] which results in decreased expression of BGLAP protein]

NCBI chr 2:173,838,518...173,839,495
Ensembl chr 2:173,838,518...173,839,495

G

BH3 interacting domain death agonist

multiple interactions

[Acetylcysteine results in decreased abundance of Reactive Oxygen Species] inhibits the reaction [sanguinarine results in increased cleavage of BID protein]; Acetylcysteine inhibits the reaction [2-hydroxy-3',5,5'-trimethoxychalcone results in increased cleavage of BID protein]; Acetylcysteine inhibits the reaction [[Cisplatin co-treated with FASLG protein] results in decreased expression of BID protein]; Acetylcysteine inhibits the reaction [cadmium acetate results in increased cleavage of BID protein]; Acetylcysteine inhibits the reaction [cordycepin results in decreased expression of BID protein]; Acetylcysteine inhibits the reaction [gingerol results in decreased expression of BID protein]; Acetylcysteine inhibits the reaction [TNFSF10 protein results in decreased expression of BID protein]
Acetylcysteine inhibits the reaction [7-ketocholesterol results in decreased expression of BID protein]

PMID:16169029 PMID:17574045 PMID:21310227 PMID:23660334 PMID:23711929 More...

NCBI chr 4:154,113,198...154,136,353
Ensembl chr 4:154,113,198...154,134,720

G

BCL2-interacting killer

multiple interactions

Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased expression of BIK protein]

NCBI chr 7:114,672,277...114,691,296
Ensembl chr 7:114,672,277...114,691,296

G

baculoviral IAP repeat-containing 2

multiple interactions

Acetylcysteine inhibits the reaction [Tosylphenylalanyl Chloromethyl Ketone results in decreased expression of BIRC2 protein]

NCBI chr 8:4,968,856...4,989,325
Ensembl chr 8:4,968,842...4,988,732

G

baculoviral IAP repeat-containing 3

multiple interactions

Acetylcysteine inhibits the reaction [Tosylphenylalanyl Chloromethyl Ketone results in decreased expression of BIRC3 protein]

NCBI chr 8:5,000,844...5,028,470
Ensembl chr 8:5,000,845...5,015,802

G

baculoviral IAP repeat-containing 5

multiple interactions

Acetylcysteine inhibits the reaction [2'-(4-chlorophenyl)-3-(4-chlorophenylidene)-5,10-dimethyl-12-methylene-decahydro-1,2-(1',3'-dioxocyclopenta(c))azuleno(4,5-b)furan-4,11-dione results in decreased expression of BIRC5 protein]; Acetylcysteine inhibits the reaction [CSC-3436 results in decreased expression of BIRC5 protein]; Acetylcysteine inhibits the reaction [gingerol results in decreased expression of BIRC5 protein]; Acetylcysteine inhibits the reaction [sepantronium results in decreased expression of BIRC5 protein]; Acetylcysteine inhibits the reaction [TNFSF10 protein results in decreased expression of BIRC5 protein]

PMID:21741372 PMID:23711929 PMID:25034532 PMID:31837377 PMID:34599545

NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380

G

basic helix-loop-helix ARNT like 1

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of BMAL1 mRNA

NCBI chr 1:167,331,756...167,430,235
Ensembl chr 1:167,331,633...167,430,231

G

bone morphogenetic protein 5

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of BMP5 mRNA

NCBI chr 8:76,517,164...76,639,925
Ensembl chr 8:76,517,164...76,639,925

G

bone morphogenetic protein 7

multiple interactions

[Ethanol co-treated with Dietary Fats co-treated with Acetylcysteine] results in increased expression of BMP7 mRNA

NCBI chr 3:161,639,915...161,716,938
Ensembl chr 3:161,516,462...161,716,788

G

BCL2 interacting protein 3

multiple interactions

Acetylcysteine inhibits the reaction [chromium hexavalent ion results in increased expression of BNIP3 protein]; Acetylcysteine inhibits the reaction [manganese chloride results in increased expression of BNIP3 protein]

PMID:19442826 PMID:36739042

NCBI chr 1:193,708,164...193,725,348
Ensembl chr 1:193,708,167...193,725,359

G

BCL2 interacting protein 3 like

multiple interactions

Acetylcysteine inhibits the reaction [sodium arsenite results in increased expression of BNIP3L protein]

NCBI chr15:41,174,594...41,197,730
Ensembl chr15:41,174,594...41,197,803

G

bisphosphoglycerate mutase

decreases expression

Acetylcysteine results in decreased expression of BPGM mRNA

NCBI chr 4:63,139,730...63,168,581
Ensembl chr 4:63,140,018...63,168,581

G

BTG anti-proliferation factor 1

decreases expression

Acetylcysteine results in decreased expression of BTG1 mRNA

NCBI chr 7:31,341,391...31,343,649
Ensembl chr 7:31,341,027...31,343,649

G

complement C3

multiple interactions

[Acetylcysteine co-treated with Atorvastatin] inhibits the reaction [sodium arsenite results in increased activity of C3 protein modified form]; Acetylcysteine inhibits the reaction [Isoproterenol results in increased expression of C3 protein]

PMID:20946910 PMID:32924446

NCBI chr 9:2,087,437...2,114,366
Ensembl chr 9:2,087,437...2,114,429

G

complement C5

multiple interactions

Acetylcysteine inhibits the reaction [Isoproterenol results in increased expression of C5 protein]

NCBI chr 3:18,270,696...18,361,994
Ensembl chr 3:18,270,696...18,361,994

G

calcium voltage-gated channel subunit alpha1 G

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of CACNA1G mRNA

NCBI chr10:79,354,998...79,422,960
Ensembl chr10:79,355,008...79,422,752

G

calpain 1

multiple interactions

Acetylcysteine inhibits the reaction [chloroacetic acid results in increased expression of CAPN1 protein]

NCBI chr 1:203,275,912...203,300,848
Ensembl chr 1:203,277,344...203,300,177

G

calpain 2

multiple interactions

Acetylcysteine inhibits the reaction [chloroacetic acid results in increased expression of CAPN2 protein]

NCBI chr13:94,150,244...94,200,969
Ensembl chr13:94,150,240...94,200,969

G

caspase 1

multiple interactions
increases cleavage

[Acetylcysteine co-treated with Cobalt] results in decreased expression of CASP1 protein; Acetylcysteine inhibits the reaction [2,3,5-trichloro-6-phenyl-(1,4)benzoquinone results in increased expression of CASP1 protein modified form]; Acetylcysteine inhibits the reaction [[Acrolein co-treated with Lipopolysaccharides] results in increased cleavage of CASP1 protein]; Acetylcysteine inhibits the reaction [[Cadmium Chloride co-treated with Lipopolysaccharides] results in increased cleavage of CASP1 protein]; Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of CASP1 mRNA]; Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of CASP1 protein]; Acetylcysteine inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of CASP1 protein]; Acetylcysteine inhibits the reaction [[Peanut Oil results in increased abundance of Particulate Matter] which results in increased cleavage of CASP1 protein]; Acetylcysteine inhibits the reaction [[Peanut Oil results in increased abundance of Particulate Matter] which results in increased expression of CASP1 mRNA]; Acetylcysteine inhibits the reaction [Acrolein promotes the reaction [Lipopolysaccharides results in increased expression of and results in increased cleavage of CASP1 protein]]; Acetylcysteine inhibits the reaction [Acrolein results in increased expression of and results in increased cleavage of CASP1 protein]; Acetylcysteine inhibits the reaction [Acrolein results in increased expression of CASP1 protein]; Acetylcysteine inhibits the reaction [APP protein results in increased expression of and results in increased cleavage of CASP1 protein]; Acetylcysteine inhibits the reaction [Asbestos, Crocidolite results in increased expression of CASP1 protein modified form]; Acetylcysteine inhibits the reaction [Chlorpyrifos results in increased expression of CASP1 protein]; Acetylcysteine inhibits the reaction [Cobalt results in increased expression of CASP1 protein modified form]; Acetylcysteine inhibits the reaction [Ethanol results in increased expression of CASP1 protein modified form]; Acetylcysteine inhibits the reaction [hydroquinone results in increased cleavage of CASP1 protein]; Acetylcysteine inhibits the reaction [Imatinib Mesylate results in increased cleavage of CASP1 protein]; Acetylcysteine inhibits the reaction [Lipopolysaccharides promotes the reaction [Acrolein results in increased expression of and results in increased cleavage of CASP1 protein]]; Acetylcysteine inhibits the reaction [Lipopolysaccharides results in increased expression of CASP1 protein]; Acetylcysteine inhibits the reaction [saikosaponin D results in increased cleavage of CASP1 protein]; Acetylcysteine inhibits the reaction [tetrachlorobenzoquinone results in increased secretion of CASP1 protein modified form]; Acetylcysteine inhibits the reaction [TNF protein results in increased cleavage of and results in increased activity of CASP1 protein]; Quercetin promotes the reaction [Acetylcysteine inhibits the reaction [Lipopolysaccharides results in increased expression of CASP1 protein]]
Acetylcysteine results in increased cleavage of CASP1 protein
Acetylcysteine inhibits the reaction [cadmium acetate results in increased cleavage of CASP1 protein]
Acetylcysteine inhibits the reaction [Aluminum Chloride results in increased expression of CASP1 mRNA]; Acetylcysteine inhibits the reaction [Aluminum Chloride results in increased expression of CASP1 protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide inhibits the reaction [anthrax toxin results in increased cleavage of CASP1 protein]]; Acetylcysteine inhibits the reaction [Glucose results in increased cleavage of CASP1 protein]; Acetylcysteine inhibits the reaction [Lipopolysaccharides results in increased cleavage of CASP1 protein]; Acetylcysteine inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of CASP1 protein]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased cleavage of CASP1 protein]; Acetylcysteine inhibits the reaction [Rotenone results in increased cleavage of CASP1 protein]; Acetylcysteine inhibits the reaction [Tobacco Smoke Pollution analog results in increased cleavage of CASP1 protein]; Acetylcysteine inhibits the reaction [Vehicle Emissions results in increased cleavage of CASP1 protein]; Acetylcysteine inhibits the reaction [Ziram results in decreased expression of and results in increased degradation of CASP1 protein]

PMID:23940760 PMID:24337744 PMID:24885895 PMID:25929180 PMID:26079697 More...

NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383

G

caspase 12

multiple interactions

Acetylcysteine inhibits the reaction [chloroacetic acid results in increased cleavage of and results in increased activity of CASP12 protein]; Acetylcysteine inhibits the reaction [methylmercuric chloride results in decreased expression of CASP12 protein]; Acetylcysteine inhibits the reaction [salubrinal promotes the reaction [Cisplatin results in increased cleavage of CASP12 protein]]
Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased cleavage of CASP12 protein]
Acetylcysteine inhibits the reaction [arsenic trioxide results in increased cleavage of CASP12 protein]; Acetylcysteine inhibits the reaction [arsenite results in increased activity of CASP12 protein]; Acetylcysteine inhibits the reaction [nickel sulfate results in increased expression of CASP12 mRNA]; Acetylcysteine inhibits the reaction [nickel sulfate results in increased expression of CASP12 protein]

PMID:18077580 PMID:21145380 PMID:21616140 PMID:25451595 PMID:28296042 More...

NCBI chr 8:2,642,296...2,669,549
Ensembl chr 8:2,642,434...2,674,037

G

caspase 14

multiple interactions

Acetylcysteine inhibits the reaction [Tobacco Smoke Pollution results in increased expression of CASP14 protein]

NCBI chr 7:10,929,759...10,932,591
Ensembl chr 7:10,926,725...10,933,405

G

caspase 2

multiple interactions

Acetylcysteine inhibits the reaction [Norepinephrine results in increased activity of CASP2 protein]
Acetylcysteine inhibits the reaction [2-hydroxy-3',5,5'-trimethoxychalcone results in increased cleavage of CASP2 protein]
Acetylcysteine inhibits the reaction [[CASP2 protein affects the susceptibility to Rotenone] which results in increased expression of BECN1 protein]; Acetylcysteine inhibits the reaction [Rotenone results in increased cleavage of CASP2 protein]

PMID:15158148 PMID:17041759 PMID:21216964 PMID:30408460

NCBI chr 4:71,149,632...71,167,388
Ensembl chr 4:71,149,669...71,167,379

G

caspase 3

increases cleavage
multiple interactions
increases activity
increases expression
decreases activity

Acetylcysteine results in increased cleavage of CASP3 protein
N-acetyl-L-cysteine inhibits the reaction [Ginkgoic acid increases cleavage of CASP3 protein in stomach]
N-acetyl-L-cysteine inhibits the reaction [apigenin-7-O-gentiobioside increases cleavage of CASP3 protein in the stomach)
Acetylcysteine results in increased activity of CASP3 protein
[Acetylcysteine co-treated with Atorvastatin] inhibits the reaction [sodium arsenite results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [25-hydroxycholesterol results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [4-hydroxy-2-nonenal results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [4-nonylphenol results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [7-ketocholesterol results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [arsenite results in decreased expression of CASP3 protein]; Acetylcysteine inhibits the reaction [bisphenol A results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased cleavage of and results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of CASP3 protein]; Acetylcysteine inhibits the reaction [Cadmium results in increased expression of CASP3 mRNA]; Acetylcysteine inhibits the reaction [Carboplatin results in increased expression of CASP3 protein]; Acetylcysteine inhibits the reaction [Carmustine results in increased activity of and results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [Chlorpyrifos results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [Cholesterol analog results in increased expression of CASP3 mRNA]; Acetylcysteine inhibits the reaction [cobaltous chloride results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [cobaltous chloride results in increased cleavage of and results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [decamethrin results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [Diquat results in increased expression of CASP3 protein modified form]; Acetylcysteine inhibits the reaction [Doxorubicin results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [Doxorubicin results in increased expression of CASP3 protein modified form]; Acetylcysteine inhibits the reaction [Estradiol results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [Fenitrothion results in increased expression of CASP3 protein]; Acetylcysteine inhibits the reaction [Glucose results in increased activity of CASP3]; Acetylcysteine inhibits the reaction [Glyphosate results in increased expression of CASP3 protein]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [Isoproterenol results in increased expression of CASP3 protein]; Acetylcysteine inhibits the reaction [JP8 aviation fuel results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [Lead results in increased expression of CASP3 mRNA]; Acetylcysteine inhibits the reaction [manganese chloride results in increased expression of CASP3 protein modified form]; Acetylcysteine inhibits the reaction [menadione epoxide results in increased cleavage of and results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [nickel sulfate results in increased expression of CASP3 protein]; Acetylcysteine inhibits the reaction [Norepinephrine results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [Palmitic Acid results in increased expression of CASP3 mRNA]; Acetylcysteine inhibits the reaction [Paraquat results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [Pilocarpine results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [Potassium Dichromate results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [Propranolol results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [Sodium Fluoride results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [Streptozocin results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [tetrachlorobenzoquinone results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [tributyltin results in increased expression of CASP3 protein modified form]
[Glucose deficiency co-treated with Acetylcysteine] results in increased activity of CASP3 protein; Acetylcysteine inhibits the reaction [1,4-naphthoquinone analog results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [10'(Z),13'(E),15'(E)-heptadecatrienylhydroquinone results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [2'-(4-chlorophenyl)-3-(4-chlorophenylidene)-5,10-dimethyl-12-methylene-decahydro-1,2-(1',3'-dioxocyclopenta(c))azuleno(4,5-b)furan-4,11-dione results in increased cleavage of and results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [2'-benzoyloxycinnamaldehyde results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine results in increased activity of and results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [2,5-diaziridinyl-3-(hydroxymethyl)-6-methyl-1,4-benzoquinone analog results in decreased expression of CASP3 protein]; Acetylcysteine inhibits the reaction [2-aminodiphenyl results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [25-hydroxycholesterol results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [3-oxo-29-noroleana-1,9(11),12-trien-2,20-dicarbonitrile results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [5-methylselenylmethyl-2'-deoxyuridine results in increased cleavage of and results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [5-phenylselenylmethyl-2'-deoxyuridine results in increased cleavage of and results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [6-iodo-5-hydroxy-eicosatrienoic acid, delta-lactone results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [7-ketocholesterol results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [8-bromo-7-methoxychrysin results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [9,10-phenanthrenequinone results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [[[Thimerosal results in increased abundance of Reactive Oxygen Species] which results in increased activity of CASP3 protein] which results in increased cleavage of PTK2 protein]; Acetylcysteine inhibits the reaction [[Berberine co-treated with Cisplatin] results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [[Cisplatin co-treated with FASLG protein] results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [[Heterocyclic Compounds binds to Thiazoles] which results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [[monomethylarsonous acid co-treated with dimethylarsinous acid co-treated with Arsenic Trioxide] results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [[Naphthalimides co-treated with Spermidine] results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of CASP3 protein modified form]; Acetylcysteine inhibits the reaction [[Pentachlorophenol co-treated with copper-1,10-phenanthroline] results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [[S100A11 mutant form results in increased susceptibility to Cisplatin] which results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [[sodium arsenite co-treated with Vitamin K 3] results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [[sulforaphane co-treated with Arsenic Trioxide] results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [[Sulindac co-treated with Arsenic Trioxide] results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [[TNFSF10 protein co-treated with gingerol] results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [[Vitamin K 2 co-treated with Arsenic Trioxide] results in increased expression of CASP3]; Acetylcysteine inhibits the reaction [ABBV-744 results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [Acrylonitrile results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [Antimycin A results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [Antimycin A results in increased expression of CASP3 mRNA]; Acetylcysteine inhibits the reaction [aristolochic acid I results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide promotes the reaction [Cisplatin results in increased cleavage of CASP3 protein]]; Acetylcysteine inhibits the reaction [Arsenic Trioxide promotes the reaction [Poly I-C results in increased activity of CASP3 protein]]; Acetylcysteine inhibits the reaction [Arsenic Trioxide promotes the reaction [Resveratrol results in increased expression of CASP3 protein]]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of CASP3 protein]; Acetylcysteine inhibits the reaction [arsenite results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [Biological Products results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [butein results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [cadmium acetate results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased cleavage of and results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [Cannabidiol results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [chelerythrine results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [chromium hexavalent ion results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [chromium tripicolinate results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [Cisplatin promotes the reaction [Arsenic Trioxide results in increased cleavage of CASP3 protein]]; Acetylcysteine inhibits the reaction [Cisplatin results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [Cisplatin results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [cordycepin results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [crocin results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [cucurbitacin E results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [Curcumin results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [cypermethrin results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [cypermethrin results in increased expression of CASP3 mRNA]; Acetylcysteine inhibits the reaction [diallyl trisulfide results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [dimethoxycurcumin results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [Dopamine results in increased activity of and results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [Doxorubicin results in increased cleavage of and results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [ellipticine results in increased cleavage of and results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [Eosine I Bluish results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [Etoposide results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [fenpyroximate results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [formononetin results in increased expression of CASP3 mRNA]; Acetylcysteine inhibits the reaction [fucoxanthin results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [ganoderic acid analog results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [ganoderic acid T analog results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [ganoderic acid T results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [geldanamycin results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [glabridin results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [Glycochenodeoxycholic Acid results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [hesperetin results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [hydroquinone results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [hydroquinone results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [isoliensinine results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [Isoproterenol results in increased activity of and results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [Malathion results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [manumycin results in increased activity of CASP3]; Acetylcysteine inhibits the reaction [menadione epoxide results in increased cleavage of and results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [Methylmercury Compounds results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [NCX 4040 results in increased cleavage of and results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [Norepinephrine results in increased activity of and results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [osimertinib results in increased expression of CASP3 protein modified form]; Acetylcysteine inhibits the reaction [Paraquat results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [platycodin D results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [Poly I-C promotes the reaction [Arsenic Trioxide results in increased activity of CASP3 protein]]; Acetylcysteine inhibits the reaction [Polystyrenes analog results in increased expression of CASP3 protein]; Acetylcysteine inhibits the reaction [Potassium Dichromate results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [Prodigiosin results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [Propofol results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [pterostilbene results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [pyrovalerone analog results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [Reactive Oxygen Species results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [Resveratrol promotes the reaction [Arsenic Trioxide results in increased expression of CASP3 protein]]; Acetylcysteine inhibits the reaction [Resveratrol results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [Resveratrol results in increased expression of CASP3 protein]; Acetylcysteine inhibits the reaction [salvin results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [sodium arsenite results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [Soot analog results in increased expression of CASP3 protein]; Acetylcysteine inhibits the reaction [sulforaphane promotes the reaction [Arsenic Trioxide results in increased cleavage of CASP3 protein]]; Acetylcysteine inhibits the reaction [surfactin peptide results in increased expression of CASP3 protein modified form]; Acetylcysteine inhibits the reaction [thymoquinone results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [thymoquinone results in increased expression of CASP3 protein modified form]; Acetylcysteine inhibits the reaction [titanium dioxide results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [TNFSF10 protein results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [Tobacco Smoke Pollution analog results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [tomentosin results in decreased expression of CASP3 protein]; Acetylcysteine inhibits the reaction [tris(1,3-dichloro-2-propyl)phosphate results in increased cleavage of CASP3 protein]; Acetylcysteine promotes the reaction [brazilin results in increased activity of CASP3 protein]; Acetylcysteine promotes the reaction [dihydromyricetin results in increased cleavage of CASP3 protein]; Acetylcysteine promotes the reaction [sinularin results in increased cleavage of CASP3 protein]; Acetylcysteine results in decreased susceptibility to [1-(3',4',5'-trimethoxyphenyl)-3-(3'',4''-dimethoxy-2'-hydroxyphenyl)propane results in increased cleavage of CASP3 protein]; Oxygen deficiency affects the reaction [Acetylcysteine results in increased activity of CASP3 protein]
Acetylcysteine results in increased expression of CASP3 protein modified form
Acetylcysteine results in decreased activity of CASP3 protein
[Acetylcysteine results in decreased abundance of Reactive Oxygen Species] inhibits the reaction [Cisplatin results in increased expression of CASP3 protein modified form]; Acetylcysteine affects the reaction [nonylphenol results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [1,3-dichloro-2-propanol results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [2,4-dibromophenol metabolite results in increased expression of CASP3 protein modified form]; Acetylcysteine inhibits the reaction [3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [[Aluminum Chloride results in increased abundance of Aluminum] which results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [[Aluminum Chloride results in increased abundance of Aluminum] which results in increased expression of CASP3 mRNA]; Acetylcysteine inhibits the reaction [[bisphenol A co-treated with Dietary Fats co-treated with Cholesterol co-treated with Cholic Acid] results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [[Mercuric Chloride co-treated with prolinedithiocarbamate] results in increased degradation of CASP3 protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased cleavage of and results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [bisphenol A results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [Cadmium results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [Chlorpyrifos results in increased activity of and results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [Cisplatin results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [Cisplatin results in increased expression of CASP3 protein modified form]; Acetylcysteine inhibits the reaction [Diethylhexyl Phthalate results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [maduramicin results in increased expression of CASP3 protein modified form]; Acetylcysteine inhibits the reaction [mancozeb results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [Mercuric Chloride results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [methylmercuric chloride results in increased expression of CASP3 protein modified form]; Acetylcysteine inhibits the reaction [Methylmercury Compounds results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [Methylmercury Compounds results in increased expression of CASP3 mRNA]; Acetylcysteine inhibits the reaction [nitrofen results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [Oxaliplatin results in increased expression of CASP3 protein]; Acetylcysteine inhibits the reaction [POMC protein promotes the reaction [cobaltous chloride results in increased activity of CASP3 protein]]; Acetylcysteine inhibits the reaction [quinone analog results in increased expression of CASP3 protein modified form]; Acetylcysteine inhibits the reaction [Simvastatin results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [T-2 Toxin results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [Zinc Oxide analog results in increased cleavage of CASP3 protein]; Resveratrol inhibits the reaction [Acetylcysteine results in increased expression of CASP3 protein modified form]

CTD
RGD

PMID:11969376 PMID:12168106 PMID:12750841 PMID:12754411 PMID:14660655 More...

RGD:127284886, RGD:127284846

NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648

G

caspase 4

multiple interactions

Acetylcysteine inhibits the reaction [Tobacco Smoke Pollution results in increased expression of CASP4 mRNA]
Acetylcysteine inhibits the reaction [[sulforaphane co-treated with Arsenic Trioxide] results in increased cleavage of CASP4 protein]; Acetylcysteine inhibits the reaction [pterostilbene results in increased activity of CASP4 protein]
Acetylcysteine inhibits the reaction [Cholesterol analog results in increased expression of CASP4 mRNA]

PMID:16137721 PMID:19477266 PMID:22922937 PMID:25341683

NCBI chr 8:2,599,017...2,635,097
Ensembl chr 8:2,598,876...2,635,092

G

caspase 6

multiple interactions

Acetylcysteine inhibits the reaction [Norepinephrine results in increased activity of CASP6 protein]
Acetylcysteine inhibits the reaction [arsenic trioxide results in increased activity of CASP6 protein]
Acetylcysteine inhibits the reaction [Potassium Dichromate results in increased cleavage of CASP6 protein]; Acetylcysteine inhibits the reaction [surfactin peptide results in increased cleavage of and results in increased activity of CASP6 protein]

PMID:15158148 PMID:19954742 PMID:24157283 PMID:37146930

NCBI chr 2:218,466,063...218,478,503
Ensembl chr 2:218,466,076...218,478,502

G

caspase 7

multiple interactions
decreases expression

Acetylcysteine inhibits the reaction [[Mercuric Chloride co-treated with prolinedithiocarbamate] results in increased degradation of CASP7 protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased activity of CASP7 protein]; Acetylcysteine inhibits the reaction [Chlorpyrifos results in increased cleavage of CASP7 protein]; Acetylcysteine inhibits the reaction [methylmercuric chloride results in increased expression of CASP7 protein modified form]; Acetylcysteine inhibits the reaction [Methylmercury Compounds results in increased expression of CASP7 mRNA]
Acetylcysteine results in decreased expression of CASP7 protein modified form
Acetylcysteine affects the reaction [[gambogic acid affects the reaction [ABCB1 protein affects the susceptibility to Doxorubicin]] which affects the cleavage of CASP7 protein]; Acetylcysteine inhibits the reaction [2,3,4,5-Tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine results in increased activity of and results in increased cleavage of CASP7 protein]; Acetylcysteine inhibits the reaction [2-hydroxy-3',5,5'-trimethoxychalcone results in increased cleavage of CASP7 protein]; Acetylcysteine inhibits the reaction [[cholix toxin, Vibrio cholerae co-treated with TNF protein] results in increased activity of CASP7 protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased activity of CASP7 protein]; Acetylcysteine inhibits the reaction [arsenite results in increased activity of CASP7 protein]; Acetylcysteine inhibits the reaction [cucurbitacin E results in increased cleavage of CASP7 protein]; Acetylcysteine inhibits the reaction [Dopamine results in increased activity of and results in increased cleavage of CASP7 protein]; Acetylcysteine inhibits the reaction [ellipticine results in increased cleavage of and results in increased activity of CASP7 protein]; Acetylcysteine inhibits the reaction [fucoxanthin results in increased cleavage of CASP7 protein]; Acetylcysteine inhibits the reaction [geldanamycin results in increased activity of CASP7 protein]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased cleavage of CASP7 protein]; Acetylcysteine inhibits the reaction [isoalantolactone results in increased expression of CASP7 protein modified form]; Acetylcysteine inhibits the reaction [Isoproterenol results in increased activity of and results in increased cleavage of CASP7 protein]; Acetylcysteine inhibits the reaction [methylselenic acid results in increased cleavage of CASP7 protein]; Acetylcysteine inhibits the reaction [Norepinephrine results in increased activity of and results in increased cleavage of CASP7 protein]; Acetylcysteine inhibits the reaction [Potassium Dichromate results in increased cleavage of CASP7 protein]; Acetylcysteine inhibits the reaction [thymoquinone results in increased cleavage of CASP7 protein]; Acetylcysteine inhibits the reaction [thymoquinone results in increased expression of CASP7 protein modified form]; Acetylcysteine inhibits the reaction [tomentosin results in decreased expression of CASP7 protein]; Acetylcysteine promotes the reaction [dihydromyricetin results in increased cleavage of CASP7 protein]
Acetylcysteine inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased cleavage of CASP7 protein]; Acetylcysteine inhibits the reaction [arsenic trioxide results in increased activity of CASP7 protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased cleavage of CASP7 protein]

PMID:17136323 PMID:19771260 PMID:20594983 PMID:21145380 PMID:21549813 More...

NCBI chr 1:255,437,438...255,476,737
Ensembl chr 1:255,437,172...255,476,729

G

caspase 8

multiple interactions

[Acetylcysteine results in decreased abundance of Reactive Oxygen Species] inhibits the reaction [Lipopolysaccharides promotes the reaction [Polystyrenes results in decreased expression of CASP8 mRNA]]; [Acetylcysteine results in decreased abundance of Reactive Oxygen Species] inhibits the reaction [Lipopolysaccharides promotes the reaction [Polystyrenes results in decreased expression of CASP8 protein]]; [Acetylcysteine results in decreased abundance of Reactive Oxygen Species] inhibits the reaction [Polystyrenes promotes the reaction [Lipopolysaccharides results in decreased expression of CASP8 mRNA]]; [Acetylcysteine results in decreased abundance of Reactive Oxygen Species] inhibits the reaction [Polystyrenes promotes the reaction [Lipopolysaccharides results in decreased expression of CASP8 protein]]; Acetylcysteine inhibits the reaction [cannabidiol hydroxyquinone results in increased activity of CASP8 protein]; Acetylcysteine inhibits the reaction [plumbagin results in increased activity of CASP8 protein]; Acetylcysteine inhibits the reaction [Simvastatin results in increased activity of CASP8 protein]; Acetylcysteine inhibits the reaction [T-2 Toxin results in increased activity of CASP8 protein]; Acetylcysteine inhibits the reaction [Zinc Oxide analog results in increased cleavage of CASP8 protein]
N-acetyl-L-cysteine inhibits the reaction [apigenin-7-O-gentiobioside increases cleavage of CASP8 protein in the stomach)
[Acetylcysteine co-treated with Atorvastatin] inhibits the reaction [sodium arsenite results in increased activity of CASP8 protein]; [Acetylcysteine co-treated with Atorvastatin] inhibits the reaction [sodium arsenite results in increased expression of CASP8 protein]; Acetylcysteine inhibits the reaction [25-hydroxycholesterol results in increased activity of CASP8 protein]; Acetylcysteine inhibits the reaction [7-ketocholesterol results in increased activity of CASP8 protein]; Acetylcysteine inhibits the reaction [Cholesterol analog results in increased activity of CASP8 protein]; Acetylcysteine inhibits the reaction [Cholesterol analog results in increased expression of CASP8 mRNA]; Acetylcysteine inhibits the reaction [Glucose results in increased activity of CASP8]; Acetylcysteine inhibits the reaction [tetrachlorobenzoquinone results in increased cleavage of CASP8 protein]
Acetylcysteine inhibits the reaction [[cholix toxin, Vibrio cholerae co-treated with TNF protein] results in increased activity of CASP8 protein]; Acetylcysteine inhibits the reaction [[Cisplatin co-treated with FASLG protein] results in increased activity of CASP8 protein]; Acetylcysteine inhibits the reaction [[Heterocyclic Compounds binds to Thiazoles] which results in increased activity of CASP8 protein]; Acetylcysteine inhibits the reaction [[TNF protein co-treated with Diclofenac] results in increased activity of CASP8 protein]; Acetylcysteine inhibits the reaction [[TNFSF10 protein co-treated with gingerol] results in increased cleavage of CASP8 protein]; Acetylcysteine inhibits the reaction [Antimycin A results in increased cleavage of CASP8 protein]; Acetylcysteine inhibits the reaction [Biological Products results in increased cleavage of CASP8 protein]; Acetylcysteine inhibits the reaction [cadmium acetate results in increased activity of CASP8 protein]; Acetylcysteine inhibits the reaction [cordycepin results in increased activity of CASP8 protein]; Acetylcysteine inhibits the reaction [diallyl trisulfide results in increased cleavage of CASP8 protein]; Acetylcysteine inhibits the reaction [Diclofenac results in increased activity of CASP8 protein]; Acetylcysteine inhibits the reaction [formononetin results in increased expression of CASP8 mRNA]; Acetylcysteine inhibits the reaction [salvin results in increased cleavage of CASP8 protein]; Acetylcysteine inhibits the reaction [sinularin results in increased cleavage of CASP8 protein]; Acetylcysteine inhibits the reaction [sodium arsenite results in increased cleavage of CASP8 protein]; Acetylcysteine inhibits the reaction [TNFSF10 protein results in increased activity of CASP8 protein]; Acetylcysteine inhibits the reaction [tomentosin results in decreased expression of CASP8 protein]; Acetylcysteine results in decreased susceptibility to [1-(3',4',5'-trimethoxyphenyl)-3-(3'',4''-dimethoxy-2'-hydroxyphenyl)propane results in increased activity of and results in increased cleavage of CASP8 protein]

CTD
RGD

PMID:16169029 PMID:17574045 PMID:18791325 PMID:19014919 PMID:19477266 More...

NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542

G

caspase 9

multiple interactions
increases expression

Acetylcysteine inhibits the reaction [Arsenic Trioxide results in decreased expression of CASP9 protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased activity of CASP9 protein]; Acetylcysteine inhibits the reaction [Cisplatin results in increased cleavage of CASP9 protein]; Acetylcysteine inhibits the reaction [methylmercuric chloride results in increased expression of CASP9 protein modified form]; Acetylcysteine inhibits the reaction [Methylmercury Compounds results in increased expression of CASP9 mRNA]; Acetylcysteine inhibits the reaction [monomethylarsonous acid results in decreased expression of CASP9 protein]; Acetylcysteine inhibits the reaction [plumbagin results in increased activity of CASP9 protein]; Acetylcysteine inhibits the reaction [salubrinal promotes the reaction [Cisplatin results in increased cleavage of CASP9 protein]]; Acetylcysteine inhibits the reaction [T-2 Toxin results in increased activity of CASP9 protein]; Acetylcysteine inhibits the reaction [Zinc Oxide analog results in increased cleavage of CASP9 protein]
N-acetyl-L-cysteine inhibits the reaction [Ginkgoic acid increases cleavage of CASP9 protein in stomach]
N-acetyl-L-cysteine inhibits the reaction [apigenin-7-O-gentiobioside increases cleavage of CASP9 protein in the stomach)
Acetylcysteine results in increased expression of CASP9 protein; Acetylcysteine results in increased expression of CASP9 protein modified form
Acetylcysteine inhibits the reaction [25-hydroxycholesterol results in increased activity of CASP9 protein]; Acetylcysteine inhibits the reaction [7-ketocholesterol results in increased activity of CASP9 protein]; Acetylcysteine inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased cleavage of CASP9 protein]; Acetylcysteine inhibits the reaction [arsenic trioxide promotes the reaction [CASP9 protein binds to CYCS protein]]; Acetylcysteine inhibits the reaction [arsenic trioxide results in increased activity of CASP9 protein]; Acetylcysteine inhibits the reaction [arsenic trioxide results in increased cleavage of CASP9 protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased activity of CASP9 protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased cleavage of CASP9 protein]; Acetylcysteine inhibits the reaction [Carboplatin results in increased expression of CASP9 protein]; Acetylcysteine inhibits the reaction [Chlorpyrifos results in increased activity of CASP9 protein]; Acetylcysteine inhibits the reaction [Cholesterol analog results in increased activity of CASP9 protein]; Acetylcysteine inhibits the reaction [Cholesterol analog results in increased expression of CASP9 mRNA]; Acetylcysteine inhibits the reaction [Glucose results in increased activity of CASP9]; Acetylcysteine inhibits the reaction [nickel sulfate results in increased expression of CASP9 mRNA]; Acetylcysteine inhibits the reaction [nickel sulfate results in increased expression of CASP9 protein]; Acetylcysteine inhibits the reaction [Norepinephrine results in increased activity of CASP9 protein]
[Glucose deficiency co-treated with Acetylcysteine] results in increased activity of CASP9 protein; [saikosaponin D co-treated with Acetylcysteine] results in decreased expression of CASP9 protein; Acetylcysteine affects the reaction [SOD2 protein affects the activity of CASP9 protein]; Acetylcysteine inhibits the reaction [10'(Z),13'(E),15'(E)-heptadecatrienylhydroquinone results in increased activity of CASP9 protein]; Acetylcysteine inhibits the reaction [2-hydroxy-3',5,5'-trimethoxychalcone results in increased cleavage of CASP9 protein]; Acetylcysteine inhibits the reaction [3-phenoxybenzoic acid results in increased expression of CASP9 mRNA]; Acetylcysteine inhibits the reaction [5-methylselenylmethyl-2'-deoxyuridine results in increased cleavage of CASP9 protein]; Acetylcysteine inhibits the reaction [5-phenylselenylmethyl-2'-deoxyuridine results in increased cleavage of CASP9 protein]; Acetylcysteine inhibits the reaction [9,10-phenanthrenequinone results in increased activity of CASP9 protein]; Acetylcysteine inhibits the reaction [[Cisplatin co-treated with FASLG protein] results in increased activity of CASP9 protein]; Acetylcysteine inhibits the reaction [[S100A11 mutant form results in increased susceptibility to Cisplatin] which results in increased cleavage of CASP9 protein]; Acetylcysteine inhibits the reaction [[sodium arsenite co-treated with Vitamin K 3] results in increased activity of CASP9 protein]; Acetylcysteine inhibits the reaction [[TNF protein co-treated with Diclofenac] results in increased activity of CASP9 protein]; Acetylcysteine inhibits the reaction [Antimycin A results in increased cleavage of CASP9 protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide promotes the reaction [Poly I-C results in increased activity of CASP9 protein]]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased activity of CASP9 protein]; Acetylcysteine inhibits the reaction [cadmium acetate results in increased activity of CASP9 protein]; Acetylcysteine inhibits the reaction [Cisplatin results in decreased expression of CASP9 protein]; Acetylcysteine inhibits the reaction [Cisplatin results in increased activity of CASP9 protein]; Acetylcysteine inhibits the reaction [Cisplatin results in increased cleavage of CASP9 protein]; Acetylcysteine inhibits the reaction [cordycepin results in increased activity of CASP9 protein]; Acetylcysteine inhibits the reaction [cypermethrin results in increased expression of CASP9 mRNA]; Acetylcysteine inhibits the reaction [diallyl trisulfide results in increased cleavage of CASP9 protein]; Acetylcysteine inhibits the reaction [Diclofenac results in increased activity of CASP9 protein]; Acetylcysteine inhibits the reaction [formononetin results in increased expression of CASP9 mRNA]; Acetylcysteine inhibits the reaction [ganoderic acid analog results in increased activity of CASP9 protein]; Acetylcysteine inhibits the reaction [ganoderic acid T analog results in increased activity of CASP9 protein]; Acetylcysteine inhibits the reaction [ganoderic acid T results in increased activity of CASP9 protein]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased cleavage of CASP9 protein]; Acetylcysteine inhibits the reaction [Lipopolysaccharides results in increased activity of CASP9 protein]; Acetylcysteine inhibits the reaction [Malathion results in increased cleavage of CASP9 protein]; Acetylcysteine inhibits the reaction [Methylmercury Compounds results in increased expression of CASP9 protein]; Acetylcysteine inhibits the reaction [oenothein B results in increased cleavage of CASP9 protein]; Acetylcysteine inhibits the reaction [Poly I-C promotes the reaction [Arsenic Trioxide results in increased activity of CASP9 protein]]; Acetylcysteine inhibits the reaction [Polystyrenes analog results in increased expression of CASP9 protein]; Acetylcysteine inhibits the reaction [Propofol results in increased cleavage of CASP9 protein]; Acetylcysteine inhibits the reaction [salvin results in increased cleavage of CASP9 protein]; Acetylcysteine inhibits the reaction [sinularin results in increased cleavage of CASP9 protein]; Acetylcysteine inhibits the reaction [Soot analog results in increased expression of CASP9 protein]; Acetylcysteine inhibits the reaction [thymoquinone results in increased cleavage of CASP9 protein]; Acetylcysteine inhibits the reaction [thymoquinone results in increased expression of CASP9 protein modified form]; Acetylcysteine inhibits the reaction [TNFSF10 protein results in increased activity of CASP9 protein]; Acetylcysteine inhibits the reaction [tomentosin results in decreased expression of CASP9 protein]; Acetylcysteine promotes the reaction [dihydromyricetin results in increased cleavage of CASP9 protein]

CTD
RGD

PMID:15158148 PMID:15496615 PMID:16169029 PMID:17309078 PMID:17574045 More...

RGD:127284886, RGD:127284846

NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626

G

catalase

multiple interactions
decreases activity
increases expression

Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased activity of CAT protein]; Acetylcysteine inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in decreased activity of CAT protein]; Acetylcysteine inhibits the reaction [Carmustine results in decreased activity of CAT protein]; Acetylcysteine inhibits the reaction [Chlorpyrifos results in decreased activity of CAT protein]; Acetylcysteine inhibits the reaction [chlorpyrifos-methyl results in decreased activity of CAT protein]; Acetylcysteine inhibits the reaction [Dichlorvos results in decreased activity of CAT protein]; Acetylcysteine inhibits the reaction [Diclofenac results in decreased activity of CAT protein]; Acetylcysteine inhibits the reaction [Dimethoate results in decreased activity of CAT protein]; Acetylcysteine inhibits the reaction [Dimethylnitrosamine results in decreased activity of CAT protein]; Acetylcysteine inhibits the reaction [Malathion results in increased activity of CAT protein]; Acetylcysteine inhibits the reaction [Mercuric Chloride results in decreased activity of CAT protein]; Acetylcysteine inhibits the reaction [Streptozocin results in decreased activity of CAT protein]; Acetylcysteine inhibits the reaction [tributyltin results in increased expression of CAT protein]; Acetylcysteine inhibits the reaction [Zinc results in decreased expression of CAT protein]; Selenium promotes the reaction [Acetylcysteine inhibits the reaction [Mercuric Chloride results in decreased activity of CAT protein]]
[Acetylcysteine results in decreased abundance of Reactive Oxygen Species] inhibits the reaction [Particulate Matter results in increased activity of CAT protein]; Acetylcysteine inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] which results in increased expression of CAT protein]; Acetylcysteine inhibits the reaction [Antimycin A results in increased expression of CAT mRNA]; Acetylcysteine inhibits the reaction [bisphenol A results in increased expression of CAT mRNA]; Acetylcysteine inhibits the reaction [ceric oxide results in decreased activity of CAT protein]; Acetylcysteine inhibits the reaction [Chlorine results in increased expression of CAT protein]; Acetylcysteine inhibits the reaction [Chlorpyrifos affects the activity of CAT protein]; Acetylcysteine inhibits the reaction [Endosulfan results in increased activity of CAT protein]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in decreased activity of CAT protein]; Acetylcysteine inhibits the reaction [Malathion results in decreased activity of CAT protein]; Acetylcysteine inhibits the reaction [mancozeb results in decreased activity of CAT protein]; Acetylcysteine inhibits the reaction [Propofol results in decreased activity of CAT protein]; Acetylcysteine inhibits the reaction [Smoke analog results in decreased activity of CAT protein]; Acetylcysteine inhibits the reaction [Sodium Fluoride results in decreased activity of CAT protein]; Acetylcysteine inhibits the reaction [tetrabromobisphenol A results in increased expression of CAT mRNA]; Acetylcysteine inhibits the reaction [TGFB1 protein results in decreased expression of CAT mRNA]; CAT protein inhibits the reaction [Acetylcysteine results in increased abundance of Hydrogen Peroxide]
Acetylcysteine results in decreased activity of CAT protein
Acetylcysteine results in increased expression of CAT protein
Acetylcysteine inhibits the reaction [[Aluminum Chloride results in increased abundance of Aluminum] which results in decreased activity of CAT protein]; Acetylcysteine inhibits the reaction [Acetaminophen results in decreased activity of CAT protein]; Acetylcysteine inhibits the reaction [Acetaminophen results in decreased expression of CAT protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in decreased activity of CAT protein]; Acetylcysteine inhibits the reaction [Ethanol results in decreased activity of CAT protein]; Acetylcysteine inhibits the reaction [mancozeb results in decreased activity of CAT protein]; Acetylcysteine promotes the reaction [XRCC1 protein results in increased activity of CAT protein]

PMID:7491977 PMID:16169029 PMID:19840221 PMID:19853593 PMID:20332008 More...

NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478

G

caveolin 1

decreases expression
multiple interactions

Acetylcysteine results in decreased expression of CAV1
Acetylcysteine inhibits the reaction [2,3,5-trichloro-6-phenyl-(1,4)benzoquinone results in increased phosphorylation of CAV1 protein]; Acetylcysteine inhibits the reaction [Rosiglitazone results in increased expression of CAV1]; Acetylcysteine results in increased ubiquitination of and results in increased degradation of CAV1 protein; Hydrogen Peroxide inhibits the reaction [Acetylcysteine results in increased ubiquitination of and results in increased degradation of CAV1 protein]

PMID:18507034 PMID:21148404 PMID:35349355

NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705

G

cystathionine beta synthase

multiple interactions

Acetylcysteine inhibits the reaction [Rotenone results in decreased expression of CBS protein]

NCBI chr20:9,708,089...9,732,623
Ensembl chr20:9,708,090...9,732,764

G

C-C motif chemokine ligand 11

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of CCL11 mRNA
Acetylcysteine inhibits the reaction [Cadmium Chloride results in decreased expression of CCL11 protein]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of CCL11 mRNA]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of CCL11 protein]; Acetylcysteine inhibits the reaction [Vehicle Emissions results in increased expression of CCL11 mRNA]; Acetylcysteine inhibits the reaction [Vehicle Emissions results in increased expression of CCL11 protein]

PMID:12576300 PMID:22129741 PMID:26138014

NCBI chr10:67,028,328...67,032,929
Ensembl chr10:67,028,328...67,032,926

G

C-C motif chemokine ligand 17

multiple interactions

Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased secretion of CCL17 protein]

NCBI chr19:10,202,128...10,203,903
Ensembl chr19:10,202,128...10,203,819

G

C-C motif chemokine ligand 2

multiple interactions

Acetylcysteine inhibits the reaction [Chlorine results in decreased secretion of CCL2 protein]; Acetylcysteine inhibits the reaction [Chloroquine results in increased expression of CCL2 mRNA]; Acetylcysteine inhibits the reaction [Dimethyl Fumarate inhibits the reaction [TNF protein results in increased expression of CCL2 mRNA]]; Acetylcysteine inhibits the reaction [Fructose results in increased secretion of CCL2 protein]; Acetylcysteine inhibits the reaction [Lipopolysaccharides results in increased expression of CCL2 protein]; Acetylcysteine inhibits the reaction [Tobacco Smoke Pollution results in increased expression of CCL2 mRNA]
Acetylcysteine inhibits the reaction [Buthionine Sulfoximine results in increased expression of CCL2 mRNA]; Acetylcysteine inhibits the reaction [Palmitates results in increased secretion of CCL2 protein]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of CCL2 mRNA]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased secretion of CCL2 protein]; Polymyxin B promotes the reaction [Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of CCL2 mRNA]]; Polymyxin B promotes the reaction [Acetylcysteine inhibits the reaction [Particulate Matter results in increased secretion of CCL2 protein]]
Acetylcysteine affects the reaction [Doxorubicin results in increased expression of CCL2 mRNA]; Acetylcysteine inhibits the reaction [Acrylonitrile results in increased expression of CCL2 mRNA]; Acetylcysteine inhibits the reaction [IL1B protein results in increased expression of CCL2 mRNA]; Acetylcysteine inhibits the reaction [PDGFB protein promotes the reaction [Nickel analog results in increased expression of CCL2 protein]]

PMID:10541287 PMID:11124598 PMID:15139008 PMID:17529908 PMID:18303122 More...

NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226

G

C-C motif chemokine ligand 20

decreases expression

Acetylcysteine results in decreased expression of CCL20 mRNA

NCBI chr 9:84,389,031...84,391,629
Ensembl chr 9:84,388,904...84,391,629

G

C-C motif chemokine ligand 22

multiple interactions

Acetylcysteine inhibits the reaction [arsenic trioxide results in decreased expression of CCL22 mRNA]

NCBI chr19:10,257,602...10,264,373
Ensembl chr19:10,257,601...10,264,400

G

C-C motif chemokine ligand 24

multiple interactions

Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of and results in increased secretion of CCL24 protein]

NCBI chr12:21,100,835...21,104,832
Ensembl chr12:21,100,835...21,104,893

G

C-C motif chemokine ligand 3

multiple interactions
decreases secretion

[Acetylcysteine co-treated with Particulate Matter] results in increased secretion of CCL3 protein; Acetylcysteine inhibits the reaction [Paraquat results in increased expression of CCL3 mRNA]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of CCL3 mRNA]; Acetylcysteine promotes the reaction [Polymyxin B inhibits the reaction [Particulate Matter results in increased secretion of CCL3 protein]]; Acetylcysteine promotes the reaction [Polymyxin B results in decreased secretion of CCL3 protein]; MYD88 protein affects the reaction [[Acetylcysteine co-treated with Particulate Matter] results in increased secretion of CCL3 protein]; Polymyxin B promotes the reaction [Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of CCL3 mRNA]]; Polymyxin B promotes the reaction [Acetylcysteine results in decreased secretion of CCL3 protein]

PMID:21765237 PMID:28555929

NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938

G

C-C motif chemokine ligand 5

multiple interactions

Acetylcysteine inhibits the reaction [TNF protein results in increased expression of CCL5 mRNA]
Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased secretion of CCL5 protein]; Acetylcysteine inhibits the reaction [TNF protein results in increased expression of CCL5 protein]; Acetylcysteine inhibits the reaction [Tobacco Smoke Pollution results in increased expression of CCL5 mRNA]

PMID:10495789 PMID:11167962 PMID:26138014 PMID:33146789

NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377

G

cellular communication network factor 1

multiple interactions
increases expression

2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Acetylcysteine results in increased expression of CCN1 protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Acetylcysteine results in increased expression of CCN1 protein]; Cycloheximide inhibits the reaction [Acetylcysteine results in increased expression of CCN1 protein]
Acetylcysteine results in increased expression of CCN1 mRNA; Acetylcysteine results in increased expression of CCN1 protein

NCBI chr 2:234,562,410...234,565,370
Ensembl chr 2:234,562,408...234,565,484

G

cellular communication network factor 2

multiple interactions

Acetylcysteine inhibits the reaction [Streptozocin results in increased expression of CCN2 protein]

NCBI chr 1:20,802,199...20,805,315
Ensembl chr 1:20,802,199...20,805,734

G

cyclin A1

multiple interactions

Acetylcysteine inhibits the reaction [sodium arsenite results in increased expression of CCNA1 protein]

NCBI chr 2:139,231,738...139,278,066
Ensembl chr 2:139,201,074...139,243,157

G

cyclin A2

multiple interactions

Acetylcysteine inhibits the reaction [bisphenol A results in decreased expression of CCNA2 protein]
Acetylcysteine inhibits the reaction [alpha-terthienylmethanol results in increased expression of CCNA2 protein]

PMID:24909818 PMID:28506552

NCBI chr 2:119,427,239...119,433,645
Ensembl chr 2:119,426,089...119,433,577

G

cyclin B1

multiple interactions

Acetylcysteine inhibits the reaction [bisphenol A results in increased expression of CCNB1 protein]; Acetylcysteine inhibits the reaction [diepoxybutane results in increased expression of CCNB1 protein]
Acetylcysteine inhibits the reaction [bisphenol A results in increased expression of CCNB1 protein]; Acetylcysteine inhibits the reaction [sinularin results in decreased phosphorylation of CCNB1 protein]

PMID:24909818 PMID:25633853 PMID:28548367 PMID:29128613

NCBI chr 2:31,912,190...31,921,163
Ensembl chr 2:31,912,193...31,921,172

G

cyclin D1

multiple interactions
decreases expression

Acetylcysteine inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of CCND1 mRNA]; Acetylcysteine inhibits the reaction [[Bortezomib co-treated with Butyrates] results in decreased expression of CCND1 protein]; Acetylcysteine inhibits the reaction [[Vorinostat co-treated with Butyrates] results in decreased expression of CCND1 protein]; Acetylcysteine inhibits the reaction [DDT results in increased phosphorylation of CCND1 protein]; Acetylcysteine inhibits the reaction [Estradiol results in increased expression of CCND1 mRNA]; Acetylcysteine inhibits the reaction [Hydrocarbons, Chlorinated analog results in increased expression of CCND1 protein]; Acetylcysteine inhibits the reaction [manumycin results in decreased expression of CCND1 protein]; Acetylcysteine inhibits the reaction [thymoquinone results in decreased expression of CCND1 protein]; Acetylcysteine inhibits the reaction [Zinc deficiency results in decreased expression of CCND1 protein]
Acetylcysteine inhibits the reaction [bisphenol A results in decreased activity of CCND1 protein]; Acetylcysteine inhibits the reaction [bisphenol A results in decreased expression of CCND1 protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of CCND1 mRNA]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of CCND1 protein]
Acetylcysteine inhibits the reaction [Acrylonitrile results in increased expression of CCND1 mRNA]; Acetylcysteine inhibits the reaction [Potassium Dichromate results in decreased expression of CCND1 protein]; Buthionine Sulfoximine inhibits the reaction [Acetylcysteine results in decreased expression of CCND1 protein]

PMID:15173093 PMID:15897899 PMID:17602960 PMID:18563748 PMID:19409983 More...

NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602

G

cyclin D2

multiple interactions

Acetylcysteine inhibits the reaction [bisphenol A results in decreased activity of CCND2 protein]; Acetylcysteine inhibits the reaction [Methoxychlor results in decreased expression of CCND2 mRNA]
Acetylcysteine inhibits the reaction [thymoquinone results in decreased expression of CCND2 protein]
Acetylcysteine inhibits the reaction [Acrylonitrile results in increased expression of CCND2 mRNA]

PMID:19615393 PMID:26332274 PMID:33485121 PMID:34627931

NCBI chr 4:159,966,883...159,989,261
Ensembl chr 4:159,962,363...159,989,495

G

cyclin D3

multiple interactions

Acetylcysteine inhibits the reaction [thymoquinone results in decreased expression of CCND3 protein]

NCBI chr 9:13,394,161...13,400,341
Ensembl chr 9:13,394,169...13,489,371

G

cyclin E1

multiple interactions

Acetylcysteine inhibits the reaction [Nitrofurazone results in increased expression of CCNE1 mRNA]
Acetylcysteine inhibits the reaction [bisphenol A results in decreased expression of CCNE1 protein]

PMID:15945272 PMID:24909818

NCBI chr 1:90,781,947...90,791,188
Ensembl chr 1:90,781,949...90,791,101

G

cyclin E2

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of CCNE2 mRNA

NCBI chr 5:24,285,078...24,298,258
Ensembl chr 5:24,284,922...24,297,632

G

CD14 molecule

multiple interactions

Acetylcysteine inhibits the reaction [Iron deficiency results in increased expression of CD14 protein]

NCBI chr18:28,335,522...28,337,383
Ensembl chr18:28,335,340...28,337,261

G

CD36 molecule

multiple interactions

Acetylcysteine inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CD36 mRNA]
Acetylcysteine inhibits the reaction [bisphenol A results in increased expression of CD36 protein]; Acetylcysteine inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CD36 protein]; Acetylcysteine inhibits the reaction [Valproic Acid results in increased expression of CD36 mRNA]; Acetylcysteine inhibits the reaction [Valproic Acid results in increased expression of CD36 protein]
Acetylcysteine inhibits the reaction [[bisphenol A co-treated with Dietary Fats co-treated with Cholesterol co-treated with Cholic Acid] results in increased expression of CD36 protein]; Acetylcysteine inhibits the reaction [Buthionine Sulfoximine results in increased expression of CD36 protein]; Acetylcysteine inhibits the reaction [Valproic Acid results in increased expression of CD36 mRNA]; Acetylcysteine inhibits the reaction [Valproic Acid results in increased expression of CD36 protein]; CD36 mRNA promotes the reaction [Acetylcysteine inhibits the reaction [Buthionine Sulfoximine results in increased uptake of malondialdehyde-low density lipoprotein, human]]

PMID:22824115 PMID:26187465 PMID:33007364 PMID:35622622 PMID:36534932

NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903

G

CD40 ligand

multiple interactions

Acetylcysteine inhibits the reaction [Cholesterol analog results in increased expression of CD40LG mRNA]
Acetylcysteine inhibits the reaction [[CD40LG protein co-treated with IL4 protein] results in increased abundance of Reactive Oxygen Species]; Acetylcysteine inhibits the reaction [[CD40LG protein co-treated with IL4 protein] results in increased expression of TP53 protein]

PMID:19477266 PMID:27634759

NCBI chr X:135,127,052...135,138,768
Ensembl chr X:135,126,969...135,138,306

G

CD86 molecule

multiple interactions

Acetylcysteine affects the reaction [Dinitrochlorobenzene affects the expression of CD86 protein]; Acetylcysteine inhibits the reaction [1,10-phenanthroline results in increased expression of CD86 mRNA]; Acetylcysteine inhibits the reaction [Dinitrochlorobenzene results in increased expression of CD86 protein]; Acetylcysteine inhibits the reaction [Ethylmercuric Chloride results in increased expression of CD86 protein]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased expression of CD86 protein]; Acetylcysteine inhibits the reaction [nickel sulfate results in increased expression of CD86 protein]; Acetylcysteine inhibits the reaction [Thimerosal results in increased expression of CD86 protein]

PMID:19033392 PMID:19641517 PMID:20417223 PMID:20457211 PMID:30842373

NCBI chr11:64,142,193...64,200,816
Ensembl chr11:64,163,828...64,200,818

G

cell division cycle 25C

multiple interactions

Acetylcysteine inhibits the reaction [diepoxybutane results in increased expression of CDC25C protein modified form]

NCBI chr18:26,335,156...26,356,199
Ensembl chr18:26,335,834...26,356,185

G

cadherin 1

multiple interactions
increases expression

Acetylcysteine inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of CDH1 mRNA]; Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of CDH1 protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased cleavage of CDH1 protein]; Acetylcysteine inhibits the reaction [DDT results in decreased expression of CDH1 mRNA]; Acetylcysteine inhibits the reaction [di-n-propyldithiocarbamate results in increased expression of CDH1 protein]; Acetylcysteine inhibits the reaction [nickel chloride results in decreased expression of CDH1 protein]; Acetylcysteine inhibits the reaction [nickel chloride results in increased methylation of CDH1 promoter]; Acetylcysteine inhibits the reaction [Particulate Matter results in decreased expression of CDH1 protein]
Acetylcysteine results in increased expression of CDH1 protein
Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in decreased expression of CDH1 protein]; Acetylcysteine inhibits the reaction [SHC1 protein results in decreased expression of CDH1 protein]

PMID:18791180 PMID:22648416 PMID:24820114 PMID:28284859 PMID:32659284 More...

NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775

G

cadherin 11

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of CDH11 mRNA

NCBI chr19:2,148,447...2,305,754
Ensembl chr19:2,148,458...2,304,272

G

cadherin 13

decreases expression

Acetylcysteine results in decreased expression of CDH13 mRNA

NCBI chr19:46,349,562...47,387,462
Ensembl chr19:46,349,430...47,387,459

G

cadherin 2

multiple interactions

Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased cleavage of CDH2 protein]
Acetylcysteine inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of CDH2 mRNA]; Acetylcysteine inhibits the reaction [DDT results in increased expression of CDH2 mRNA]

PMID:23876460 PMID:24820114 PMID:28284859

NCBI chr18:7,776,704...7,990,934
Ensembl chr18:7,776,704...7,990,167

G

cadherin 5

multiple interactions

Acetylcysteine inhibits the reaction [27-hydroxycholesterol results in decreased expression of CDH5 protein]

NCBI chr19:815,415...854,478
Ensembl chr19:815,411...854,368

G

cyclin-dependent kinase 1

multiple interactions

Acetylcysteine inhibits the reaction [diepoxybutane results in increased expression of CDK1 protein]
Acetylcysteine inhibits the reaction [sinularin results in decreased phosphorylation of CDK1 protein]

PMID:25633853 PMID:28548367

NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408

G

cyclin-dependent kinase 4

multiple interactions

Acetylcysteine inhibits the reaction [Methoxychlor results in decreased expression of CDK4 mRNA]
Acetylcysteine inhibits the reaction [tubocapsenolide A results in increased degradation of CDK4 protein]

PMID:18442981 PMID:19615393

NCBI chr 7:62,886,124...62,889,562
Ensembl chr 7:62,883,105...62,942,403

G

cyclin-dependent kinase 7

multiple interactions

Acetylcysteine inhibits the reaction [Acetaminophen results in increased expression of CDK7 mRNA]

NCBI chr 2:31,840,558...31,865,422
Ensembl chr 2:31,840,558...31,865,383

G

cyclin-dependent kinase inhibitor 1A

multiple interactions
decreases expression
increases expression

Acetylcysteine inhibits the reaction [2,2'-azobis(2-amidinopropane) results in increased expression of CDKN1A protein]; Acetylcysteine inhibits the reaction [Aristolochic Acids results in increased expression of CDKN1A protein]; Acetylcysteine inhibits the reaction [camphorquinone results in increased expression of CDKN1A protein]; Acetylcysteine inhibits the reaction [Cisplatin results in increased expression of CDKN1A]; Acetylcysteine inhibits the reaction [diaziquone results in increased expression of CDKN1A mRNA]; Acetylcysteine inhibits the reaction [Doxorubicin results in increased expression of CDKN1A protein]; Acetylcysteine inhibits the reaction [ethylenimine quinone results in increased expression of CDKN1A mRNA]; Acetylcysteine inhibits the reaction [manumycin results in decreased expression of CDKN1A protein]; Acetylcysteine inhibits the reaction [Methotrexate results in increased expression of CDKN1A mRNA]; Acetylcysteine inhibits the reaction [Methylcholanthrene results in increased expression of CDKN1A protein]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of CDKN1A mRNA]; Acetylcysteine inhibits the reaction [sodium arsenite results in increased expression of CDKN1A mRNA]; Acetylcysteine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of CDKN1A protein]; Acetylcysteine promotes the reaction [AHR protein binds to CDKN1A enhancer]; IL7R mRNA alternative form promotes the reaction [Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of CDKN1A mRNA]]
Acetylcysteine results in decreased expression of CDKN1A mRNA
Acetylcysteine inhibits the reaction [2,4-dibromophenol metabolite results in increased expression of CDKN1A protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of CDKN1A protein]; Acetylcysteine inhibits the reaction [dihydrolipoic acid results in increased expression of CDKN1A mRNA]; Acetylcysteine inhibits the reaction [Nicotine results in increased expression of CDKN1A mRNA]; Acetylcysteine inhibits the reaction [Nicotine results in increased expression of CDKN1A protein]; Acetylcysteine inhibits the reaction [quinone analog results in increased expression of CDKN1A protein]
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of CDKN1A mRNA; Acetylcysteine inhibits the reaction [Acrylonitrile results in increased expression of CDKN1A mRNA]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of CDKN1A protein]; Buthionine Sulfoximine inhibits the reaction [Acetylcysteine results in increased expression of CDKN1A protein]

PMID:8943236 PMID:9343371 PMID:12208374 PMID:15496615 PMID:15978937 More...

NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585

G

cyclin-dependent kinase inhibitor 1B

increases expression
multiple interactions

Acetylcysteine results in increased expression of CDKN1B protein
Acetylcysteine inhibits the reaction [Methylcholanthrene results in increased expression of CDKN1B protein]; Acetylcysteine inhibits the reaction [tomentosin results in increased expression of CDKN1B protein]; Acetylcysteine promotes the reaction [AHR protein binds to CDKN1B enhancer]
Buthionine Sulfoximine inhibits the reaction [Acetylcysteine results in increased expression of CDKN1B protein]

PMID:17602960 PMID:18022818 PMID:30917517

NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982

G

cyclin-dependent kinase inhibitor 2A

multiple interactions

Acetylcysteine inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] inhibits the reaction [DNMT1 protein binds to CDKN2A promoter]]; Acetylcysteine inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] inhibits the reaction [EZH2 protein binds to CDKN2A promoter]]; Acetylcysteine inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] promotes the reaction [KDM2A protein binds to CDKN2A promoter]]; Acetylcysteine inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] promotes the reaction [TET1 protein binds to CDKN2A promoter]]; Acetylcysteine inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] which results in increased expression of CDKN2A protein]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of CDKN2A mRNA]; IL7R mRNA alternative form promotes the reaction [Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of CDKN2A mRNA]]
Acetylcysteine inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] which results in increased expression of CDKN2A protein]; Acetylcysteine inhibits the reaction [Nicotine results in increased expression of CDKN2A mRNA]; Acetylcysteine inhibits the reaction [Nicotine results in increased expression of CDKN2A protein]

PMID:31551408 PMID:32473187 PMID:35303175

NCBI chr 5:103,984,949...103,992,143
Ensembl chr 5:103,984,949...104,003,149

G

CCAAT/enhancer binding protein alpha

multiple interactions

Acetylcysteine inhibits the reaction [INS1 protein results in increased expression of CEBPA protein]
Acetylcysteine inhibits the reaction [bisphenol A results in increased expression of CEBPA protein]

PMID:27117918 PMID:35622622

NCBI chr 1:87,759,631...87,762,303
Ensembl chr 1:87,759,433...87,762,412

G

CCAAT/enhancer binding protein beta

multiple interactions

Acetylcysteine inhibits the reaction [LHB protein results in increased abundance of CEBPB mRNA]

NCBI chr 3:156,398,035...156,399,466
Ensembl chr 3:156,397,052...156,399,473

G

CCAAT/enhancer binding protein epsilon

multiple interactions

Acetylcysteine inhibits the reaction [3-phenoxybenzoic acid inhibits the reaction [Tretinoin results in increased expression of CEBPE mRNA]]; Acetylcysteine inhibits the reaction [cypermethrin inhibits the reaction [Tretinoin results in increased expression of CEBPE mRNA]]

NCBI chr15:28,169,711...28,171,471
Ensembl chr15:28,169,704...28,171,814

G

CASP8 and FADD-like apoptosis regulator

multiple interactions

Acetylcysteine inhibits the reaction [CSC-3436 results in decreased expression of CFLAR protein]; Acetylcysteine inhibits the reaction [gingerol results in decreased expression of CFLAR protein]; Acetylcysteine inhibits the reaction [shogaol promotes the reaction [TNFSF10 protein results in decreased expression of CFLAR protein modified form]]

PMID:25034532 PMID:25619640 PMID:34599545

NCBI chr 9:60,185,338...60,236,173
Ensembl chr 9:60,185,452...60,237,034

G

CF transmembrane conductance regulator

multiple interactions

Acetylcysteine inhibits the reaction [Ozone results in decreased expression of CFTR mRNA]; Acetylcysteine inhibits the reaction [Ozone results in decreased expression of CFTR protein]

NCBI chr 4:46,561,269...46,728,759
Ensembl chr 4:46,560,885...46,728,756

G

choline O-acetyltransferase

increases expression
multiple interactions

Acetylcysteine results in increased expression of CHAT protein
[Ascorbic Acid co-treated with alpha-Tocopherol co-treated with Acetylcysteine] results in increased expression of CHAT protein; Tobacco Smoke Pollution inhibits the reaction [[Ascorbic Acid co-treated with alpha-Tocopherol co-treated with Acetylcysteine] results in increased expression of CHAT protein]

NCBI chr16:7,657,362...7,717,093
Ensembl chr16:7,657,362...7,717,093

G

checkpoint kinase 1

multiple interactions

Acetylcysteine inhibits the reaction [Acetaminophen results in increased expression of CHEK1 mRNA]; Acetylcysteine inhibits the reaction [Doxorubicin promotes the reaction [ATM protein results in increased phosphorylation of CHEK1 protein]]
Acetylcysteine inhibits the reaction [diepoxybutane results in increased expression of CHEK1 protein modified form]

PMID:15489221 PMID:25633853 PMID:33971260

NCBI chr 8:36,420,565...36,443,477
Ensembl chr 8:36,420,569...36,441,009

G

checkpoint kinase 2

multiple interactions
increases expression

Acetylcysteine inhibits the reaction [Aristolochic Acids results in increased expression of CHEK2 protein modified form]; Acetylcysteine inhibits the reaction [dorsomorphin results in increased phosphorylation of CHEK2 protein]; Acetylcysteine inhibits the reaction [Doxorubicin promotes the reaction [ATM protein results in increased phosphorylation of CHEK2 protein]]; Acetylcysteine inhibits the reaction [Resveratrol results in increased phosphorylation of CHEK2 protein]; Acetylcysteine inhibits the reaction [usnic acid results in increased expression of CHEK2 protein]
Acetylcysteine results in increased expression of CHEK2 protein

PMID:15489221 PMID:23274516 PMID:24792323 PMID:24933654 PMID:31715134

NCBI chr12:45,788,823...45,821,382
Ensembl chr12:45,788,827...45,821,286

G

choline kinase alpha

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of CHKA mRNA

NCBI chr 1:201,076,804...201,125,517
Ensembl chr 1:201,076,860...201,125,516

G

cholinergic receptor, muscarinic 2

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of CHRM2 mRNA
Acetylcysteine inhibits the reaction [Cadmium Chloride results in decreased expression of CHRM2 mRNA]

PMID:22129741 PMID:29253600

NCBI chr 4:65,015,408...65,149,104
Ensembl chr 4:65,014,144...65,149,103

G

cholinergic receptor, muscarinic 3

multiple interactions

Acetylcysteine inhibits the reaction [Cadmium Chloride results in decreased expression of CHRM3 mRNA]

NCBI chr17:60,005,137...60,467,250
Ensembl chr17:60,005,202...60,467,278

G

cholinergic receptor, muscarinic 4

multiple interactions

Acetylcysteine inhibits the reaction [Cadmium Chloride results in decreased expression of CHRM4 mRNA]

NCBI chr 3:77,893,425...77,901,166
Ensembl chr 3:77,893,425...77,901,159

G

component of inhibitor of nuclear factor kappa B kinase complex

decreases activity

Acetylcysteine results in decreased activity of CHUK protein

NCBI chr 1:242,959,539...242,995,066
Ensembl chr 1:242,959,760...242,995,065

G

cytokine inducible SH2-containing protein

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of CISH mRNA

NCBI chr 8:107,972,306...107,977,254
Ensembl chr 8:107,972,306...107,977,250

G

creatine kinase B

multiple interactions

[Deferoxamine co-treated with Acetylcysteine] inhibits the reaction [Acetaminophen results in decreased activity of CKB protein]; [Deferoxamine co-treated with Acetylcysteine] inhibits the reaction [Carbon Tetrachloride results in decreased activity of CKB protein]

NCBI chr 6:130,729,420...130,732,301
Ensembl chr 6:130,729,423...130,732,315

G

creatine kinase, M-type

multiple interactions
decreases secretion

Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in decreased expression of CKM mRNA]
Acetylcysteine results in decreased secretion of CKM protein

PMID:9689591 PMID:21912612

NCBI chr 1:79,061,390...79,071,721
Ensembl chr 1:79,061,456...79,071,720

G

claudin 1

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of CLDN1 mRNA; Acetylcysteine inhibits the reaction [Glyphosate results in decreased expression of CLDN1 protein]
Acetylcysteine inhibits the reaction [bisphenol A results in decreased expression of CLDN1 mRNA]
Acetylcysteine inhibits the reaction [Arsenic Trioxide results in decreased expression of CLDN1 protein]; Acetylcysteine inhibits the reaction [Particulate Matter results in decreased expression of CLDN1 protein]

PMID:22129741 PMID:28115242 PMID:29235125 PMID:32687961 PMID:33485121 More...

NCBI chr11:74,421,569...74,436,728
Ensembl chr11:74,421,569...74,436,724

G

claudin 4

multiple interactions

Acetylcysteine inhibits the reaction [Sodium Chloride results in increased expression of CLDN4 mRNA]; Acetylcysteine inhibits the reaction [Sodium Chloride results in increased expression of CLDN4 protein]
Acetylcysteine inhibits the reaction [bisphenol A results in decreased expression of CLDN4 mRNA]

PMID:23816505 PMID:33485121

NCBI chr12:21,751,638...21,753,436
Ensembl chr12:21,751,331...21,753,436

G

claudin 5

multiple interactions

Acetylcysteine inhibits the reaction [9,10-phenanthrenequinone results in decreased expression of and affects the localization of CLDN5 protein]; Acetylcysteine inhibits the reaction [9,10-phenanthrenequinone results in decreased expression of CLDN5 mRNA]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in decreased expression of CLDN5 protein]

PMID:28115242 PMID:34391839

NCBI chr11:82,212,822...82,214,248
Ensembl chr11:82,211,475...82,214,992

G

C-type lectin domain containing 9A

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of CLEC9A mRNA

NCBI chr 4:162,859,742...162,875,742
Ensembl chr 4:162,860,308...162,875,352

G

CDC-like kinase 1

multiple interactions

Acetylcysteine inhibits the reaction [elesclomol results in increased expression of CLK1 mRNA]

NCBI chr 9:59,947,774...59,959,002
Ensembl chr 9:59,947,764...59,957,000

G

clusterin

multiple interactions

Acetylcysteine promotes the reaction [Chlorine results in increased expression of CLU protein]

NCBI chr15:40,161,068...40,200,315
Ensembl chr15:40,174,617...40,200,315

G

chymase 1

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of CMA1 mRNA

NCBI chr15:29,417,451...29,420,233
Ensembl chr15:29,417,451...29,420,233

G

ciliary neurotrophic factor

multiple interactions

Acetylcysteine inhibits the reaction [Cadmium Chloride results in decreased expression of CNTF protein]; Acetylcysteine inhibits the reaction [Mercuric Chloride inhibits the reaction [CNTF protein results in increased phosphorylation of STAT1 protein]]; Acetylcysteine inhibits the reaction [Mercuric Chloride inhibits the reaction [CNTF protein results in increased phosphorylation of STAT3 protein]]

PMID:16896058 PMID:26138014

NCBI chr 1:209,887,854...209,889,877
Ensembl chr 1:209,887,854...209,889,877

G

collagen type XVIII alpha 1 chain

multiple interactions

Acetylcysteine inhibits the reaction [cobaltous chloride results in decreased expression of COL18A1 mRNA]; Acetylcysteine inhibits the reaction [cobaltous chloride results in decreased expression of COL18A1 protein]

NCBI chr20:11,474,104...11,582,593
Ensembl chr20:11,474,104...11,582,593

G

collagen type I alpha 1 chain

decreases expression
multiple interactions

Acetylcysteine results in decreased expression of COL1A1 mRNA
Acetylcysteine inhibits the reaction [[Aluminum Chloride results in increased abundance of Aluminum] which results in decreased expression of COL1A1 mRNA]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased expression of COL1A1 protein]
Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of COL1A1 mRNA]; Buthionine Sulfoximine inhibits the reaction [Acetylcysteine results in decreased expression of COL1A1 mRNA]; Buthionine Sulfoximine inhibits the reaction [Acetylcysteine results in decreased expression of COL1A1 protein]
Acetylcysteine results in decreased expression of COL1A1 mRNA; Acetylcysteine results in decreased expression of COL1A1 protein

PMID:11710721 PMID:17602960 PMID:32659284 PMID:34547296 PMID:36493885

NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624

G

collagen type I alpha 2 chain

decreases expression

Acetylcysteine results in decreased expression of COL1A2 mRNA

NCBI chr 4:32,563,938...32,598,868
Ensembl chr 4:32,563,381...32,598,867

G

collagen type IV alpha 1 chain

decreases expression

Acetylcysteine results in decreased expression of COL4A1 mRNA

NCBI chr16:78,183,533...78,294,412
Ensembl chr16:78,183,533...78,294,412

G

collagen like tail subunit of asymmetric acetylcholinesterase

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of COLQ mRNA; Acetylcysteine inhibits the reaction [[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of COLQ mRNA]

NCBI chr16:6,731,850...6,824,973
Ensembl chr16:6,731,858...6,787,107

G

COPI coat complex subunit gamma 1

multiple interactions

Acetylcysteine inhibits the reaction [Paraquat results in increased methylation of COPG1 mRNA]

NCBI chr 4:120,366,540...120,392,502
Ensembl chr 4:120,366,542...120,415,616

G

cytochrome c oxidase subunit 4i1

multiple interactions

Acetylcysteine inhibits the reaction [Cadmium Chloride results in decreased expression of COX4I1 mRNA]; Acetylcysteine inhibits the reaction [Monocrotophos results in decreased expression of COX4I1 mRNA]

PMID:35403558 PMID:36493885

NCBI chr19:48,721,680...48,727,920
Ensembl chr19:48,721,199...48,727,921

G

carboxypeptidase E

decreases expression

Acetylcysteine results in decreased expression of CPE mRNA

NCBI chr16:25,030,276...25,142,231
Ensembl chr16:25,030,276...25,142,233

G

complexin 1

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of CPLX1 mRNA

NCBI chr14:1,184,677...1,216,392

G

carnitine palmitoyltransferase 1A

multiple interactions

[Acetylcysteine co-treated with Dietary Fats] results in increased expression of CPT1A mRNA

NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055

G

carnitine palmitoyltransferase 1B

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of CPT1B mRNA

NCBI chr 7:120,491,354...120,500,833
Ensembl chr 7:120,491,354...120,500,404

G

CASP2 and RIPK1 domain containing adaptor with death domain

decreases expression

Acetylcysteine results in decreased expression of CRADD mRNA

NCBI chr 7:29,940,240...29,952,907
Ensembl chr 7:29,798,586...29,952,907

G

carnitine O-acetyltransferase

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of CRAT mRNA

NCBI chr 3:13,675,684...13,689,282
Ensembl chr 3:13,675,684...13,689,255

G

cAMP responsive element binding protein 1

multiple interactions

Acetylcysteine inhibits the reaction [cobaltous chloride results in increased phosphorylation of and results in increased activity of CREB1 protein]; Acetylcysteine inhibits the reaction [methylmercuric chloride results in increased phosphorylation of CREB1 protein]
Acetylcysteine inhibits the reaction [4-biphenylamine results in increased expression of CREB1 protein]

PMID:18375950 PMID:32433928 PMID:36813253

NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816

G

cAMP responsive element modulator

multiple interactions

Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased expression of CREM mRNA]

NCBI chr17:54,238,889...54,305,989
Ensembl chr17:54,239,030...54,305,989

G

cryptochrome circadian regulator 1

multiple interactions

Acetylcysteine inhibits the reaction [Acetaminophen results in increased expression of CRY1 mRNA]

NCBI chr 7:18,529,823...18,594,092
Ensembl chr 7:18,529,823...18,594,091

G

crystallin, alpha B

multiple interactions

Acetylcysteine inhibits the reaction [arsenite results in increased expression of CRYAB protein]

NCBI chr 8:51,093,441...51,099,161
Ensembl chr 8:51,093,441...51,099,157

G

crystallin, gamma A

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of CRYGA mRNA; Acetylcysteine inhibits the reaction [[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of CRYGA mRNA]

NCBI chr 9:66,482,176...66,484,638
Ensembl chr 9:66,482,176...66,509,896

G

citrate synthase

multiple interactions

Acetylcysteine inhibits the reaction [Atorvastatin results in increased expression of CS mRNA]
Acetylcysteine inhibits the reaction [NOX4 protein promotes the reaction [[Lipopolysaccharides co-treated with IFNG1 protein] results in increased expression of CS protein]]
Acetylcysteine promotes the reaction [FMR1 5' UTR mutant form results in decreased activity of CS protein]

PMID:21775390 PMID:27385396 PMID:36762617

NCBI chr 7:758,074...791,421
Ensembl chr 7:758,345...791,421

G

colony stimulating factor 1

multiple interactions

Acetylcysteine inhibits the reaction [Buthionine Sulfoximine results in increased expression of CSF1 mRNA]

NCBI chr 2:195,377,215...195,396,608
Ensembl chr 2:195,377,215...195,411,704

G

colony stimulating factor 1 receptor

multiple interactions

[Acetylcysteine co-treated with CSF1R protein co-treated with TNFSF11 protein] results in decreased expression of ATP6V0D2 mRNA; [Acetylcysteine co-treated with CSF1R protein co-treated with TNFSF11 protein] results in decreased expression of CTSK mRNA; Acetylcysteine affects the reaction [[NFE2L2 protein affects the susceptibility to sodium arsenite] affects the reaction [[CSF1R protein co-treated with TNFSF11 protein] affects the expression of ATP6V0D2 mRNA]]; Acetylcysteine affects the reaction [[NFE2L2 protein affects the susceptibility to sodium arsenite] affects the reaction [[CSF1R protein co-treated with TNFSF11 protein] affects the expression of CTSK mRNA]]; Acetylcysteine inhibits the reaction [[sodium arsenite co-treated with CSF1R protein co-treated with TNFSF11 protein] results in increased expression of ATP6V0D2 mRNA]; Acetylcysteine inhibits the reaction [[sodium arsenite co-treated with CSF1R protein co-treated with TNFSF11 protein] results in increased expression of CTSK mRNA]

NCBI chr18:54,546,673...54,590,418
Ensembl chr18:54,546,659...54,590,415

G

colony stimulating factor 2

multiple interactions

Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of and results in increased secretion of CSF2 protein]; Acetylcysteine inhibits the reaction [Particulate Matter analog results in increased secretion of CSF2 protein]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of CSF2 mRNA]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased secretion of CSF2 protein]; Acetylcysteine inhibits the reaction [Vehicle Emissions analog results in increased secretion of CSF2 protein]; Acetylcysteine inhibits the reaction [Vehicle Emissions results in increased secretion of CSF2 protein]

PMID:10645887 PMID:19460412 PMID:26138014 PMID:29753051

NCBI chr10:38,386,945...38,388,926
Ensembl chr10:38,386,945...38,389,199

G

colony stimulating factor 3 receptor

multiple interactions

Acetylcysteine inhibits the reaction [3-phenoxybenzoic acid inhibits the reaction [Tretinoin results in increased expression of CSF3R mRNA]]; Acetylcysteine inhibits the reaction [cypermethrin inhibits the reaction [Tretinoin results in increased expression of CSF3R mRNA]]

NCBI chr 5:138,298,605...138,318,224
Ensembl chr 5:138,301,506...138,317,881

G

cystatin C

multiple interactions

Acetylcysteine inhibits the reaction [Acetaminophen results in increased expression of CST3 protein]

NCBI chr 3:136,336,923...136,340,796
Ensembl chr 3:136,336,920...136,340,822

G

catenin beta 1

multiple interactions

Acetylcysteine inhibits the reaction [TALDO1 gene mutant form results in decreased phosphorylation of CTNNB1 protein]
Acetylcysteine inhibits the reaction [27-hydroxycholesterol inhibits the reaction [GSK3B protein binds to CTNNB1 protein]]; Acetylcysteine inhibits the reaction [27-hydroxycholesterol inhibits the reaction [YWHAH protein binds to CTNNB1 protein]]; Acetylcysteine inhibits the reaction [27-hydroxycholesterol results in increased expression of and results in increased activity of CTNNB1 protein]; Acetylcysteine inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of and affects the localization of CTNNB1 protein]; Acetylcysteine inhibits the reaction [DDT results in increased expression of and results in decreased phosphorylation of CTNNB1 protein]; Acetylcysteine inhibits the reaction [NCX 4040 results in increased cleavage of CTNNB1 protein]; Acetylcysteine inhibits the reaction [quinocetone results in decreased expression of CTNNB1 protein]; Acetylcysteine inhibits the reaction [sodium arsenite results in increased expression of CTNNB1 protein]

PMID:16282376 PMID:19436114 PMID:24961358 PMID:24968063 PMID:28321046 More...

NCBI chr 8:120,640,008...120,667,110
Ensembl chr 8:120,639,995...120,667,111

G

chymotrypsin C

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of CTRC mRNA

NCBI chr 5:154,147,314...154,156,540
Ensembl chr 5:154,147,316...154,156,528

G

chymotrypsin-like

multiple interactions

Acetylcysteine inhibits the reaction [plumbagin results in decreased activity of CTRL protein]

NCBI chr19:33,827,279...33,829,129
Ensembl chr19:33,827,229...33,833,626

G

cathepsin B

multiple interactions

Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of CTSB mRNA]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of CTSB mRNA]

PMID:29307831 PMID:31319114

NCBI chr15:37,389,636...37,410,508
Ensembl chr15:37,389,629...37,410,500

G

cathepsin D

multiple interactions

Acetylcysteine inhibits the reaction [4-hydroxy-2-nonenal results in increased expression of CTSD mRNA]

NCBI chr 1:197,527,467...197,539,343
Ensembl chr 1:197,527,467...197,539,488

G

cathepsin K

multiple interactions

[Acetylcysteine co-treated with CSF1R protein co-treated with TNFSF11 protein] results in decreased expression of CTSK mRNA; Acetylcysteine affects the reaction [[NFE2L2 protein affects the susceptibility to sodium arsenite] affects the reaction [[CSF1R protein co-treated with TNFSF11 protein] affects the expression of CTSK mRNA]]; Acetylcysteine inhibits the reaction [[sodium arsenite co-treated with CSF1R protein co-treated with TNFSF11 protein] results in increased expression of CTSK mRNA]

NCBI chr 2:183,058,586...183,069,551
Ensembl chr 2:183,058,569...183,069,550

G

cathepsin L

multiple interactions

Acetylcysteine inhibits the reaction [Berberine results in decreased cleavage of CTSL protein]

NCBI chr17:764,370...770,533
Ensembl chr17:764,309...770,548

G

cut-like homeobox 2

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of CUX2 mRNA; Acetylcysteine inhibits the reaction [[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of CUX2 mRNA]

NCBI chr12:34,507,723...34,707,581
Ensembl chr12:34,520,959...34,705,806

G

C-X-C motif chemokine ligand 1

decreases expression
multiple interactions

Acetylcysteine results in decreased expression of CXCL1 protein
Acetylcysteine analog inhibits the reaction [2-chloroethyl ethyl sulfide results in increased expression of CXCL1 protein]; Acetylcysteine analog inhibits the reaction [Lipopolysaccharides results in increased expression of CXCL1 protein]

PMID:17395010 PMID:18257742

NCBI chr14:17,193,364...17,195,143
Ensembl chr14:17,193,365...17,195,215

G

C-X-C motif chemokine ligand 12

multiple interactions

Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased secretion of CXCL12 protein]
Acetylcysteine inhibits the reaction [Buthionine Sulfoximine results in increased expression of CXCL12 mRNA]

PMID:26138014 PMID:35123994

NCBI chr 4:150,388,326...150,401,173
Ensembl chr 4:150,388,325...150,401,168

G

C-X-C motif chemokine ligand 2

multiple interactions

Acetylcysteine inhibits the reaction [arsenic trioxide results in increased expression of CXCL2 mRNA]; Acetylcysteine inhibits the reaction [Vanadates results in increased expression of CXCL2 mRNA]
Acetylcysteine inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased secretion of CXCL2 protein]; Acetylcysteine inhibits the reaction [Paraquat results in increased expression of CXCL2 protein]

PMID:10718115 PMID:16919916 PMID:19350554 PMID:21507677

NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075

G

C-X-C motif chemokine ligand 3

decreases expression
multiple interactions

Acetylcysteine results in decreased expression of CXCL1 protein
Acetylcysteine inhibits the reaction [Particulate Matter results in increased secretion of CXCL1 protein]; Acetylcysteine inhibits the reaction [TNF protein results in increased expression of CXCL1 mRNA]; MYD88 protein affects the reaction [Acetylcysteine inhibits the reaction [Particulate Matter results in increased secretion of CXCL1 protein]]; MYD88 protein affects the reaction [Polymyxin B promotes the reaction [Acetylcysteine inhibits the reaction [Particulate Matter results in increased secretion of CXCL1 protein]]]; Polymyxin B promotes the reaction [Acetylcysteine inhibits the reaction [Particulate Matter results in increased secretion of CXCL1 protein]]

PMID:17395010 PMID:24316229 PMID:28555929

NCBI chr14:17,287,727...17,289,451
Ensembl chr14:17,270,146...17,289,511

G

C-X-C motif chemokine ligand 6

multiple interactions

Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of and results in increased secretion of CXCL6 protein]

NCBI chr14:17,310,790...17,312,250
Ensembl chr14:17,310,426...17,313,093

G

cytochrome b-245 alpha chain

multiple interactions

Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of CYBA protein]

NCBI chr19:50,487,598...50,495,669
Ensembl chr19:50,487,597...50,495,721

G

cytochrome b-245 beta chain

multiple interactions

Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of CYBB protein]; Acetylcysteine inhibits the reaction [Doxorubicin results in increased expression of CYBB protein]

PMID:21195169 PMID:29087013

NCBI chr X:13,358,101...13,392,570
Ensembl chr X:13,359,430...13,392,586

G

cytochrome c, somatic

multiple interactions
decreases expression

Acetylcysteine inhibits the reaction [dimethoxycurcumin affects the localization of CYCS protein]; Acetylcysteine inhibits the reaction [hydroquinone results in increased expression of CYCS protein]; Acetylcysteine inhibits the reaction [Methylmercury Compounds results in increased expression of CYCS protein]; Acetylcysteine inhibits the reaction [Polystyrenes analog results in increased expression of CYCS protein]; Acetylcysteine inhibits the reaction [sodium arsenite affects the localization of CYCS protein]; Acetylcysteine inhibits the reaction [surfactin peptide affects the localization of CYCS protein]; Acetylcysteine inhibits the reaction [TNFSF10 protein affects the localization of CYCS protein]
Acetylcysteine results in decreased expression of CYCS protein
Acetylcysteine inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] affects the localization of CYCS protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide affects the localization of CYCS protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide promotes the reaction [CASP9 protein binds to CYCS protein]]; Acetylcysteine inhibits the reaction [Carboplatin results in increased expression of CYCS protein]; Acetylcysteine inhibits the reaction [nickel sulfate results in increased expression of CYCS mRNA]
Acetylcysteine inhibits the reaction [1,3-dichloro-2-propanol results in increased expression of CYCS protein]; Acetylcysteine inhibits the reaction [[Aluminum Chloride results in increased abundance of Aluminum] which results in increased expression of CYCS mRNA]; Acetylcysteine inhibits the reaction [Methylmercury Compounds affects the localization of CYCS protein]

PMID:18483861 PMID:19536524 PMID:19954742 PMID:21145380 PMID:21221209 More...

NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054
Ensembl chr18:79,651,378...79,654,054

G

cytochrome c, testis

multiple interactions

Acetylcysteine inhibits the reaction [Estradiol results in increased expression of CYCT protein]

NCBI chr 3:61,290,090...61,297,158
Ensembl chr 3:60,913,562...61,297,158

G

cytochrome P450, family 11, subfamily a, polypeptide 1

multiple interactions

Acetylcysteine inhibits the reaction [Dimethoate results in decreased expression of CYP11A1 mRNA]; Acetylcysteine inhibits the reaction [nickel sulfate results in decreased expression of CYP11A1 mRNA]; Acetylcysteine inhibits the reaction [nickel sulfate results in decreased expression of CYP11A1 protein]

PMID:26769589 PMID:29567110

NCBI chr 8:58,422,807...58,434,342
Ensembl chr 8:58,404,669...58,434,338

G

cytochrome P450, family 11, subfamily b, polypeptide 2

multiple interactions

Acetylcysteine inhibits the reaction [anacetrapib results in increased expression of CYP11B1 mRNA]; Acetylcysteine inhibits the reaction [dalcetrapib results in increased expression of CYP11B1 mRNA]; Acetylcysteine inhibits the reaction [torcetrapib results in increased expression of CYP11B1 mRNA]

NCBI chr 7:106,838,590...106,845,004
Ensembl chr 7:106,838,590...106,845,004

G

cytochrome P450, family 11, subfamily b, polypeptide 3

multiple interactions

Acetylcysteine inhibits the reaction [anacetrapib results in increased expression of CYP11B2 mRNA]; Acetylcysteine inhibits the reaction [dalcetrapib results in increased expression of CYP11B2 mRNA]; Acetylcysteine inhibits the reaction [torcetrapib results in increased expression of CYP11B2 mRNA]

NCBI chr 7:106,808,559...106,814,048
Ensembl chr 7:106,808,559...106,814,048

G

cytochrome P450, family 17, subfamily a, polypeptide 1

multiple interactions

Acetylcysteine inhibits the reaction [nickel sulfate results in decreased expression of CYP17A1 mRNA]; Acetylcysteine inhibits the reaction [nickel sulfate results in decreased expression of CYP17A1 protein]

NCBI chr 1:245,535,462...245,543,148
Ensembl chr 1:245,535,462...245,541,573

G

cytochrome P450, family 1, subfamily a, polypeptide 1

multiple interactions
increases expression

[Acetylcysteine inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]] which results in decreased expression of NQO1 mRNA; Acetylcysteine affects the reaction [Curcumin affects the reaction [6-formylindolo(3,2-b)carbazole results in increased activity of CYP1A1 protein]]; Acetylcysteine inhibits the reaction [1-(4-chlorophenyl)-benzo-2,5-quinone results in increased expression of CYP1A1 mRNA]; Acetylcysteine inhibits the reaction [2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [6-formylindolo(3,2-b)carbazole results in increased activity of CYP1A1 protein]]; Acetylcysteine inhibits the reaction [hydroquinone results in increased expression of CYP1A1 protein]; Acetylcysteine inhibits the reaction [Nicotine results in increased expression of CYP1A1 mRNA]; Acetylcysteine inhibits the reaction [Nicotine results in increased expression of CYP1A1 protein]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of CYP1A1 mRNA]; Acetylcysteine inhibits the reaction [sodium arsenite inhibits the reaction [6-formylindolo(3,2-b)carbazole results in increased expression of CYP1A1 mRNA]]; Acetylcysteine inhibits the reaction [sodium arsenite results in increased expression of CYP1A1 mRNA]; Acetylcysteine inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]; Acetylcysteine promotes the reaction [Particulate Matter results in increased expression of CYP1A1 mRNA]
Acetylcysteine results in increased expression of CYP1A1 protein
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in increased expression of CYP1A1 mRNA; Acetylcysteine inhibits the reaction [Fenitrothion results in increased expression of CYP1A1 mRNA]
[Acetylcysteine co-treated with 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide] inhibits the reaction [6-formylindolo(3,2-b)carbazole results in increased activity of CYP1A1 protein]; Acetylcysteine affects the reaction [andrographolide affects the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]]; Acetylcysteine affects the reaction [beta-Naphthoflavone results in increased expression of CYP1A1 mRNA]; Acetylcysteine inhibits the reaction [Benzo(a)pyrene results in decreased activity of CYP1A1 protein]; Acetylcysteine inhibits the reaction [beta-Naphthoflavone results in decreased activity of CYP1A1 protein]; Acetylcysteine inhibits the reaction [chromium trioxide results in increased expression of CYP1A1 mRNA]; Acetylcysteine inhibits the reaction [sodium arsenite results in increased expression of CYP1A1 mRNA]; Acetylcysteine promotes the reaction [6-formylindolo(3,2-b)carbazole results in increased activity of CYP1A1 protein]

PMID:15044633 PMID:15621696 PMID:16274885 PMID:19033395 PMID:20801209 More...

NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125

G

cytochrome P450, family 1, subfamily a, polypeptide 2

multiple interactions

[Acetylcysteine co-treated with Zinc co-treated with Selenium] inhibits the reaction [dimethyl mercury results in decreased expression of CYP1A2 protein]; Acetylcysteine inhibits the reaction [[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of CYP1A2 mRNA]; Acetylcysteine inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of and results in increased activity of CYP1A2 protein]; Acetylcysteine inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of CYP1A2 mRNA]; Acetylcysteine inhibits the reaction [Paraquat results in increased expression of and results in increased activity of CYP1A2 protein]; Acetylcysteine inhibits the reaction [Paraquat results in increased expression of CYP1A2 mRNA]
[CYP1A2 protein co-treated with Acetylcysteine] results in increased metabolism of Emodin metabolite

PMID:21424224 PMID:22129741 PMID:23159886 PMID:27989148

NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312

G

cytochrome P450, family 1, subfamily b, polypeptide 1

multiple interactions

Acetylcysteine promotes the reaction [Particulate Matter results in increased expression of CYP1B1 mRNA]
Acetylcysteine inhibits the reaction [[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of CYP1B1 mRNA]

PMID:21703343 PMID:22129741

NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917

G

cytochrome P450, family 26, subfamily C, polypeptide 1

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of CYP26C1 mRNA

NCBI chr 1:235,458,961...235,468,433
Ensembl chr 1:235,459,356...235,466,842

G

cytochrome P450, family 2, subfamily b, polypeptide 1

multiple interactions

Acetylcysteine promotes the reaction [Phenobarbital results in increased expression of CYP2B1 mRNA]

PMID:11353799 PMID:14722249

NCBI chr 1:81,518,387...81,544,999
Ensembl chr 1:81,518,408...81,542,052

G

cytochrome P450, family 2, subfamily C, polypeptide 6

multiple interactions

[CYP2C19 protein co-treated with Acetylcysteine] results in increased metabolism of Emodin metabolite

NCBI chr 1:237,938,521...237,976,238
Ensembl chr 1:237,693,094...238,057,596

G

cytochrome P450, family 2, subfamily e, polypeptide 1

multiple interactions

[Acetylcysteine co-treated with Zinc co-treated with Selenium] inhibits the reaction [dimethyl mercury results in decreased expression of CYP2E1 protein]; Acetylcysteine inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of and results in increased activity of CYP2E1 protein]; Acetylcysteine inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of CYP2E1 mRNA]; Acetylcysteine inhibits the reaction [Maneb results in increased expression of and results in increased activity of CYP2E1 protein]; Acetylcysteine inhibits the reaction [Maneb results in increased expression of CYP2E1 mRNA]; Acetylcysteine inhibits the reaction [Paraquat results in increased expression of and results in increased activity of CYP2E1 protein]; Acetylcysteine inhibits the reaction [Paraquat results in increased expression of CYP2E1 mRNA]; Acetylcysteine promotes the reaction [Acrylonitrile results in increased expression of CYP2E1 mRNA]
Acetylcysteine inhibits the reaction [Ethanol results in increased expression of CYP2E1 mRNA]
Acetylcysteine inhibits the reaction [Acetaminophen results in increased expression of CYP2E1 mRNA]; Acetylcysteine inhibits the reaction [Acetaminophen results in increased expression of CYP2E1 protein]

PMID:21424224 PMID:23159886 PMID:26332274 PMID:30423402 PMID:35713687

NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023

G

cytochrome P450, family 3, subfamily a, polypeptide 2

multiple interactions

[CYP3A4 protein co-treated with Acetylcysteine] results in increased metabolism of Emodin metabolite; Acetylcysteine inhibits the reaction [[CYP3A4 protein co-treated with neferine] results in decreased abundance of Glutathione]

PMID:25451576 PMID:27989148

NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008

G

cytochrome P450, family 4, subfamily a, polypeptide 1

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of CYP4A1 mRNA; Acetylcysteine promotes the reaction [Bezafibrate results in increased expression of CYP4A1 mRNA]

PMID:19647067 PMID:22129741

NCBI chr 5:129,123,323...129,137,464
Ensembl chr 5:129,123,336...129,137,464

G

death associated protein kinase 1

multiple interactions

Acetylcysteine inhibits the reaction [Cholesterol analog results in increased expression of DAPK1 mRNA]

NCBI chr17:3,930,223...4,090,991
Ensembl chr17:3,930,213...4,090,991

G

DDHD domain containing 1

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of DDHD1 mRNA

NCBI chr15:18,824,389...18,891,036
Ensembl chr15:18,824,394...18,890,952

G

DNA-damage inducible transcript 3

increases expression
decreases expression
multiple interactions

Acetylcysteine results in increased expression of DDIT3 mRNA; Acetylcysteine results in increased expression of DDIT3 protein
Acetylcysteine results in decreased expression of DDIT3 protein
Acetylcysteine inhibits the reaction [4-hydroxy-2-nonenal results in increased expression of DDIT3 mRNA]; Acetylcysteine inhibits the reaction [arsenic trioxide results in increased expression of DDIT3 protein]; Acetylcysteine inhibits the reaction [arsenite results in increased expression of DDIT3 protein]; Acetylcysteine inhibits the reaction [Cadmium results in increased expression of DDIT3 protein]; Acetylcysteine inhibits the reaction [gadolinium chloride results in increased expression of DDIT3 protein]; Acetylcysteine inhibits the reaction [nickel sulfate results in increased expression of DDIT3 mRNA]; Acetylcysteine inhibits the reaction [nickel sulfate results in increased expression of DDIT3 protein]; Acetylcysteine inhibits the reaction [tetrachlorobenzoquinone results in increased expression of DDIT3 protein]
4-phenylbutyric acid promotes the reaction [Acetylcysteine inhibits the reaction [tris(1,3-dichloro-2-propyl)phosphate results in increased expression of DDIT3 protein]]; Acetylcysteine inhibits the reaction [(3R)-((2,3-dihydro-5-methyl-3-((4-morpholinyl)methyl)pyrrolo-(1,2,3-de)-1,4-benzoxazin-6-yl)(1-naphthalenyl))methanone results in increased expression of DDIT3 mRNA]; Acetylcysteine inhibits the reaction [(4-methyl-1-naphthyl)-(1-pentylindol-3-yl)methanone results in increased expression of DDIT3 mRNA]; Acetylcysteine inhibits the reaction [2,3,5-trichloro-6-phenyl-(1,4)benzoquinone results in increased expression of DDIT3 protein]; Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of DDIT3 protein]; Acetylcysteine inhibits the reaction [Acrylamide results in increased expression of DDIT3 mRNA]; Acetylcysteine inhibits the reaction [Arsenic Trioxide promotes the reaction [Resveratrol results in increased expression of DDIT3 protein]]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of DDIT3 protein]; Acetylcysteine inhibits the reaction [Benomyl results in increased expression of DDIT3 protein]; Acetylcysteine inhibits the reaction [bisphenol A results in increased expression of DDIT3 protein]; Acetylcysteine inhibits the reaction [Cadmium results in increased expression of DDIT3]; Acetylcysteine inhibits the reaction [CSC-3436 results in increased expression of DDIT3 protein]; Acetylcysteine inhibits the reaction [Curcumin results in increased expression of DDIT3 mRNA]; Acetylcysteine inhibits the reaction [discretamine results in increased expression of DDIT3 protein]; Acetylcysteine inhibits the reaction [Ethacrynic Acid results in increased expression of DDIT3 mRNA]; Acetylcysteine inhibits the reaction [Ethylmercury Compounds results in increased expression of DDIT3 mRNA]; Acetylcysteine inhibits the reaction [fangchinoline results in increased expression of DDIT3 protein]; Acetylcysteine inhibits the reaction [hesperetin results in increased expression of DDIT3 protein]; Acetylcysteine inhibits the reaction [ilimaquinone results in increased expression of DDIT3 mRNA]; Acetylcysteine inhibits the reaction [plumbagin results in increased expression of DDIT3 protein]; Acetylcysteine inhibits the reaction [pterostilbene results in increased expression of DDIT3 protein]; Acetylcysteine inhibits the reaction [Quercetin results in increased expression of DDIT3 protein]; Acetylcysteine inhibits the reaction [raspberry ketone results in increased expression of DDIT3 mRNA]; Acetylcysteine inhibits the reaction [Resveratrol promotes the reaction [Arsenic Trioxide results in increased expression of DDIT3 protein]]; Acetylcysteine inhibits the reaction [Resveratrol results in increased expression of DDIT3 protein]; Acetylcysteine inhibits the reaction [rhododendrol results in increased expression of DDIT3 mRNA]; Acetylcysteine inhibits the reaction [scutebarbatine A results in increased expression of DDIT3 protein]; Acetylcysteine inhibits the reaction [shogaol results in increased expression of DDIT3 mRNA]; Acetylcysteine inhibits the reaction [shogaol results in increased expression of DDIT3 protein]; Acetylcysteine inhibits the reaction [sodium arsenite results in increased expression of DDIT3 protein]; Acetylcysteine inhibits the reaction [tanshinone results in increased expression of DDIT3 protein]; Acetylcysteine inhibits the reaction [tert-Butylhydroperoxide results in increased expression of DDIT3 protein]; Acetylcysteine inhibits the reaction [Tobacco Smoke Pollution analog results in increased expression of DDIT3 protein]; Acetylcysteine inhibits the reaction [tris(1,3-dichloro-2-propyl)phosphate results in increased expression of DDIT3 protein]; Acetylcysteine inhibits the reaction [Ursolic Acid results in increased expression of DDIT3 protein]; Acetylcysteine inhibits the reaction [withaferin A results in increased expression of DDIT3 protein]; Acetylcysteine promotes the reaction [4-phenylbutyric acid inhibits the reaction [tris(1,3-dichloro-2-propyl)phosphate results in increased expression of DDIT3 protein]]
Acetylcysteine inhibits the reaction [[bisphenol A co-treated with Dietary Fats co-treated with Cholesterol co-treated with Cholic Acid] results in increased expression of DDIT3 protein]; Acetylcysteine inhibits the reaction [alpha-naphthoflavone results in increased expression of DDIT3 protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of DDIT3 mRNA]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of DDIT3 protein]; Acetylcysteine inhibits the reaction [Brefeldin A results in increased expression of DDIT3 protein]; Acetylcysteine inhibits the reaction [Cadmium results in increased expression of DDIT3 protein]; Acetylcysteine inhibits the reaction [chloroacetic acid results in increased expression of DDIT3 protein]; Acetylcysteine inhibits the reaction [Chlorpyrifos results in increased expression of DDIT3 protein]; Acetylcysteine inhibits the reaction [Cisplatin results in increased expression of DDIT3 protein]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased expression of DDIT3 mRNA]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased expression of DDIT3 protein]; Acetylcysteine inhibits the reaction [methylmercuric chloride results in increased expression of DDIT3 protein]; Acetylcysteine inhibits the reaction [salubrinal promotes the reaction [Cisplatin results in increased expression of DDIT3 protein]]; Acetylcysteine inhibits the reaction [Thapsigargin results in increased expression of DDIT3 protein]; Acetylcysteine promotes the reaction [perfluorooctanoic acid results in increased expression of DDIT3 mRNA]

PMID:16084531 PMID:17171638 PMID:18077580 PMID:18384088 PMID:19722195 More...

NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201

G

DNA-damage-inducible transcript 4

multiple interactions

Acetylcysteine inhibits the reaction [withaferin A results in increased expression of DDIT4 protein]

NCBI chr20:27,891,989...27,894,088
Ensembl chr20:27,891,998...27,894,105

G

defensin beta 105A

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of DEFB12 mRNA

NCBI chr16:70,136,218...70,138,645
Ensembl chr16:70,725,701...70,728,143
Ensembl chr16:70,725,701...70,728,143

G

defensin beta 18

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of DEFB18 mRNA

NCBI chr 9:20,852,230...20,853,247
Ensembl chr 9:20,852,300...20,853,211

G

defensin beta 49

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of DEFB49 mRNA; Acetylcysteine inhibits the reaction [[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of DEFB49 mRNA]

NCBI chr 9:20,832,686...20,837,352
Ensembl chr 9:20,832,686...20,837,352

G

defensin beta 5

decreases expression

Acetylcysteine results in decreased expression of DEFB4A mRNA

NCBI chr16:70,612,985...70,615,389
Ensembl chr16:70,613,146...70,615,467

G

diacylglycerol O-acyltransferase 2

multiple interactions

Acetylcysteine inhibits the reaction [Valproic Acid results in increased expression of DGAT2 mRNA]; Acetylcysteine inhibits the reaction [Valproic Acid results in increased expression of DGAT2 protein]

NCBI chr 1:153,454,078...153,484,432
Ensembl chr 1:153,454,080...153,484,428

G

dihydrofolate reductase

multiple interactions

Acetylcysteine inhibits the reaction [bisphenol A results in decreased expression of DHFR mRNA]

NCBI chr 2:23,585,876...23,611,199
Ensembl chr 2:23,586,031...23,613,713

G

desert hedgehog signaling molecule

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of DHH mRNA

NCBI chr 7:130,050,910...130,056,406
Ensembl chr 7:130,050,910...130,056,406

G

iodothyronine deiodinase 2

multiple interactions

Acetylcysteine inhibits the reaction [Hydrogen Peroxide inhibits the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased activity of DIO2 protein]]

NCBI chr 6:109,665,523...109,679,809
Ensembl chr 6:109,665,523...109,679,809

G

iodothyronine deiodinase 3

multiple interactions

Acetylcysteine inhibits the reaction [[Hydrogen Peroxide co-treated with Sodium Selenite] promotes the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased activity of DIO3 protein]]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide promotes the reaction [8-Bromo Cyclic Adenosine Monophosphate results in increased activity of DIO3 protein]]

NCBI chr 6:129,285,747...129,287,608
Ensembl chr 6:129,285,749...129,286,660

G

dickkopf WNT signaling pathway inhibitor 1

multiple interactions

Acetylcysteine inhibits the reaction [4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of DKK1 mRNA]

NCBI chr 1:228,381,521...228,385,202
Ensembl chr 1:228,381,521...228,385,202

G

discs large MAGUK scaffold protein 4

multiple interactions

Acetylcysteine inhibits the reaction [Particulate Matter results in decreased expression of DLG4 mRNA]; Acetylcysteine inhibits the reaction [Particulate Matter results in decreased expression of DLG4 protein]

PMID:27624276 PMID:28153600

NCBI chr10:54,740,700...54,769,097
Ensembl chr10:54,739,470...54,767,153

G

doublesex and mab-3 related transcription factor 1

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of DMRT1 mRNA

NCBI chr 1:223,142,859...223,241,333
Ensembl chr 1:223,142,859...223,241,333

G

dynein, axonemal, heavy chain 3

multiple interactions

Acetylcysteine inhibits the reaction [[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of DNAH3 mRNA]

NCBI chr 1:174,305,929...174,479,490
Ensembl chr 1:174,306,644...174,479,474

G

dynein, axonemal, intermediate chain 1

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of DNAI1 mRNA

NCBI chr 5:56,730,179...56,800,926
Ensembl chr 5:56,730,179...56,800,925

G

DnaJ heat shock protein family (Hsp40) member B1

multiple interactions

Acetylcysteine inhibits the reaction [elesclomol results in increased expression of DNAJB1 mRNA]

NCBI chr19:24,522,731...24,526,419
Ensembl chr19:24,522,717...24,526,458

G

DnaJ heat shock protein family (Hsp40) member B4

multiple interactions

Acetylcysteine inhibits the reaction [elesclomol results in increased expression of DNAJB4 mRNA]

NCBI chr 2:241,129,346...241,159,272
Ensembl chr 2:241,130,340...241,159,089

G

DnaJ heat shock protein family (Hsp40) member B9

increases expression

Acetylcysteine results in increased expression of DNAJB9 mRNA

NCBI chr 6:61,270,385...61,276,795
Ensembl chr 6:61,269,913...61,275,063

G

dynamin 1-like

multiple interactions

Acetylcysteine inhibits the reaction [15-deoxyprostaglandin J2 affects the reaction [DNM1L protein binds to DNM1L protein binds to DNM1L protein binds to DNM1L protein]]; Acetylcysteine inhibits the reaction [bisphenol A results in increased phosphorylation of DNM1L protein]; Acetylcysteine inhibits the reaction [Doxorubicin results in increased expression of DNM1L protein]
Acetylcysteine inhibits the reaction [Polystyrenes analog results in increased expression of and results in increased phosphorylation of DNM1L protein]
Acetylcysteine inhibits the reaction [Diethylhexyl Phthalate affects the localization of DNM1L protein]; Acetylcysteine inhibits the reaction [Diethylhexyl Phthalate results in increased expression of and affects the phosphorylation of DNM1L protein]

PMID:20307494 PMID:30641872 PMID:31408635 PMID:37084995 PMID:37499777

NCBI chr11:84,581,216...84,632,382
Ensembl chr11:84,581,216...84,631,482

G

DNA methyltransferase 1

multiple interactions

[Acetylcysteine co-treated with Hydrogen Peroxide] results in increased expression of DNMT1 mRNA; [Acetylcysteine co-treated with Hydrogen Peroxide] results in increased methylation of DNMT1 promoter; Acetylcysteine inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] inhibits the reaction [DNMT1 protein binds to CDKN2A promoter]]; Acetylcysteine inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] which results in decreased expression of DNMT1 protein]; Acetylcysteine inhibits the reaction [sodium arsenite results in increased expression of DNMT1 mRNA]; Acetylcysteine inhibits the reaction [sodium arsenite results in increased expression of DNMT1 protein]

PMID:29854080 PMID:31150806 PMID:31551408

NCBI chr 8:19,440,611...19,486,659
Ensembl chr 8:19,440,611...19,486,659

G

DNA methyltransferase 3 beta

multiple interactions

Acetylcysteine inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] which results in decreased expression of DNMT3B protein]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of DNMT3B protein]

PMID:26942697 PMID:31551408

NCBI chr 3:142,130,588...142,169,128
Ensembl chr 3:142,130,592...142,169,124

G

desmoplakin

multiple interactions

Acetylcysteine inhibits the reaction [Dietary Fats results in increased expression of DSP mRNA]

NCBI chr17:26,623,602...26,671,692
Ensembl chr17:26,623,588...26,671,800

G

dentin sialophosphoprotein

increases expression

Acetylcysteine results in increased expression of DSPP mRNA

NCBI chr14:5,565,562...5,571,669
Ensembl chr14:5,565,629...5,571,672

G

dual specificity phosphatase 1

multiple interactions

Acetylcysteine inhibits the reaction [Cadmium results in increased expression of DUSP1 mRNA]; Acetylcysteine inhibits the reaction [Cadmium results in increased expression of DUSP1 protein]

NCBI chr10:16,680,478...16,683,275

G

dual specificity phosphatase 4

increases expression

Acetylcysteine results in increased expression of DUSP4 mRNA

NCBI chr16:57,376,659...57,398,161
Ensembl chr16:57,377,229...57,398,138

G

deoxyuridine triphosphatase

multiple interactions

Acetylcysteine inhibits the reaction [beta-hydroxyisovalerylshikonin results in decreased phosphorylation of and results in decreased activity of DUT protein]

NCBI chr 3:112,498,864...112,509,994
Ensembl chr 3:112,498,982...112,510,771

G

E2F transcription factor 1

multiple interactions

Acetylcysteine inhibits the reaction [5-nitroso-8-quinolinol results in decreased expression of E2F1 protein]

NCBI chr 3:143,064,535...143,075,362
Ensembl chr 3:143,049,478...143,075,361

G

endothelin 1

multiple interactions

Acetylcysteine inhibits the reaction [EDN1 protein results in increased phosphorylation of and results in increased activity of EGFR protein]; Acetylcysteine inhibits the reaction [EDN1 protein results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [EDN1 protein results in increased phosphorylation of MAPK3 protein]
Acetylcysteine inhibits the reaction [Paraquat results in increased expression of EDN1 mRNA]
Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased expression of EDN1 mRNA]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased secretion of EDN1 protein]

PMID:14623829 PMID:16261333 PMID:21765237

NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885

G

EF-hand calcium binding domain 3

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of EFCAB3 mRNA

NCBI chr10:89,583,526...90,077,260
Ensembl chr10:89,644,522...90,077,259

G

ephrin A1

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of EFNA1 mRNA

NCBI chr 2:174,681,676...174,689,061
Ensembl chr 2:174,681,682...174,690,866

G

ephrin B2

decreases expression

Acetylcysteine results in decreased expression of EFNB2 mRNA

NCBI chr16:80,783,389...80,827,420
Ensembl chr16:80,783,417...80,824,391

G

epidermal growth factor

multiple interactions

Acetylcysteine inhibits the reaction [[EGF co-treated with Colforsin co-treated with Rotenone] results in increased expression of HSPD1 mRNA]; Acetylcysteine inhibits the reaction [[EGF co-treated with Colforsin co-treated with Rotenone] results in increased expression of SOD1 mRNA]; Acetylcysteine inhibits the reaction [[EGF co-treated with Colforsin co-treated with Rotenone] results in increased expression of SOD1 protein]; Acetylcysteine inhibits the reaction [[EGF co-treated with Colforsin co-treated with Rotenone] results in increased expression of SOD2 mRNA]; Acetylcysteine inhibits the reaction [[EGF co-treated with Colforsin co-treated with Rotenone] results in increased expression of SOD2 protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in decreased expression of EGF protein]; Acetylcysteine inhibits the reaction [cyadox results in increased expression of EGF]; Acetylcysteine inhibits the reaction [EGF protein results in increased secretion of VEGFA mRNA]; Acetylcysteine inhibits the reaction [EGF protein results in increased secretion of VEGFA protein]
Acetylcysteine inhibits the reaction [EGF protein results in increased abundance of 8-hydroxyguanosine]; Acetylcysteine inhibits the reaction [EGF protein results in increased abundance of Peroxides]

PMID:11158190 PMID:11214823 PMID:26138014 PMID:30265530 PMID:32092105

NCBI chr 2:218,219,408...218,302,359
Ensembl chr 2:218,219,415...218,302,064

G

epidermal growth factor receptor

multiple interactions

Acetylcysteine inhibits the reaction [Acetaminophen results in increased phosphorylation of and results in increased activity of EGFR protein]; Acetylcysteine inhibits the reaction [Asbestos, Crocidolite results in increased activity of EGFR protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of EGFR mRNA]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of EGFR protein]; Acetylcysteine inhibits the reaction [Diethylnitrosamine results in increased phosphorylation of and results in increased activity of EGFR protein]; Acetylcysteine inhibits the reaction [LHB protein results in increased phosphorylation of and results in increased activity of EGFR protein]
Acetylcysteine inhibits the reaction [AGT protein results in increased phosphorylation of and results in increased activity of EGFR protein]; Acetylcysteine inhibits the reaction [Asbestos, Crocidolite results in increased expression of EGFR protein]; Acetylcysteine inhibits the reaction [EDN1 protein results in increased phosphorylation of and results in increased activity of EGFR protein]
Acetylcysteine inhibits the reaction [2'-benzoyloxycinnamaldehyde results in increased phosphorylation of EGFR protein]; Acetylcysteine inhibits the reaction [Cadmium results in increased phosphorylation of EGFR protein]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of and results in increased activity of EGFR protein]

PMID:10640773 PMID:14660655 PMID:15520183 PMID:15849355 PMID:16261333 More...

NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382

G

egl-9 family hypoxia-inducible factor 1

multiple interactions

Acetylcysteine inhibits the reaction [bisphenol A results in increased expression of EGLN1 mRNA]

NCBI chr19:52,867,900...52,907,308
Ensembl chr19:52,869,486...52,907,777

G

early growth response 1

multiple interactions

Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of EGR1 mRNA]; Acetylcysteine inhibits the reaction [Doxorubicin results in increased expression of EGR1 mRNA]
Acetylcysteine inhibits the reaction [platycodin D results in increased expression of EGR1 mRNA]

PMID:10625299 PMID:18804340 PMID:19010381

NCBI chr18:26,462,967...26,466,766
Ensembl chr18:26,462,981...26,466,766

G

early growth response 2

multiple interactions

Acetylcysteine inhibits the reaction [arsenic trioxide results in decreased expression of EGR2 mRNA]

NCBI chr20:21,051,270...21,056,322
Ensembl chr20:21,051,277...21,055,562

G

EI24, autophagy associated transmembrane protein

multiple interactions

Acetylcysteine promotes the reaction [Tobacco Smoke Pollution results in increased expression of EI24 mRNA]

NCBI chr 8:36,494,289...36,510,653
Ensembl chr 8:36,494,289...36,510,571

G

eukaryotic translation initiation factor 2A

multiple interactions

Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased phosphorylation of EIF2A protein]; Acetylcysteine inhibits the reaction [chloroacetic acid results in increased phosphorylation of EIF2A protein]; Acetylcysteine inhibits the reaction [Cisplatin results in increased phosphorylation of EIF2A protein]; Acetylcysteine inhibits the reaction [salubrinal promotes the reaction [Cisplatin results in increased phosphorylation of EIF2A protein]]
Acetylcysteine inhibits the reaction [Cadmium results in decreased phosphorylation of EIF2A protein]

PMID:21616140 PMID:25451595 PMID:27658547 PMID:29373603

NCBI chr 2:142,761,303...142,794,767
Ensembl chr 2:142,761,416...142,795,068

G

eukaryotic translation initiation factor 2 alpha kinase 3

multiple interactions
decreases expression

Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of EIF2AK3 mRNA]; Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased phosphorylation of EIF2AK3 protein]; Acetylcysteine inhibits the reaction [Benomyl results in increased expression of EIF2AK3 protein]; Acetylcysteine inhibits the reaction [chrysophanic acid results in increased phosphorylation of EIF2AK3 protein]; Acetylcysteine inhibits the reaction [pendulone results in increased phosphorylation of EIF2AK3 protein]; Acetylcysteine inhibits the reaction [pterostilbene results in increased phosphorylation of EIF2AK3 protein]; Acetylcysteine inhibits the reaction [sodium arsenite results in increased phosphorylation of EIF2AK3 protein]; Acetylcysteine results in increased phosphorylation of and results in increased activity of EIF2AK3 protein
Acetylcysteine inhibits the reaction [tetrachlorobenzoquinone results in increased expression of EIF2AK3 protein modified form]
Acetylcysteine results in decreased expression of EIF2AK3 protein modified form
Acetylcysteine inhibits the reaction [chloroacetic acid results in increased phosphorylation of EIF2AK3 protein]; Acetylcysteine inhibits the reaction [methylmercuric chloride results in increased phosphorylation of EIF2AK3 protein]; Acetylcysteine inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased phosphorylation of EIF2AK3 protein]

PMID:19722195 PMID:25341683 PMID:25451595 PMID:27484784 PMID:27784618 More...

NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911

G

eukaryotic translation initiation factor 2 subunit alpha

multiple interactions

Acetylcysteine inhibits the reaction [Acrylamide results in increased phosphorylation of EIF2S1 protein]; Acetylcysteine inhibits the reaction [chrysophanic acid results in increased phosphorylation of EIF2S1 protein]; Acetylcysteine inhibits the reaction [sodium arsenite results in increased phosphorylation of EIF2S1 protein]; Acetylcysteine inhibits the reaction [Tobacco Smoke Pollution analog results in increased phosphorylation of EIF2S1 protein]; Acetylcysteine inhibits the reaction [tris(1,3-dichloro-2-propyl)phosphate results in increased phosphorylation of EIF2S1 protein]
Acetylcysteine inhibits the reaction [4-hydroxy-2-nonenal results in increased phosphorylation of EIF2S1 protein]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of EIF2S1 protein]; Acetylcysteine inhibits the reaction [tetrachlorobenzoquinone results in increased expression of EIF2S1 protein modified form]
Acetylcysteine inhibits the reaction [6-formylindolo(3,2-b)carbazole results in increased phosphorylation of EIF2S1 protein]; Acetylcysteine inhibits the reaction [Indican results in increased phosphorylation of EIF2S1 protein]; Acetylcysteine inhibits the reaction [methylmercuric chloride results in increased phosphorylation of EIF2S1 protein]; Acetylcysteine inhibits the reaction [sodium arsenite results in increased expression of EIF2S1 protein]

PMID:15788408 PMID:16324875 PMID:21911445 PMID:24291486 PMID:25568320 More...

NCBI chr 6:97,672,829...97,697,499
Ensembl chr 6:97,672,766...97,706,225

G

eukaryotic translation initiation factor 4E binding protein 1

multiple interactions

Acetylcysteine inhibits the reaction [4-nonylphenol results in decreased phosphorylation of EIF4EBP1 protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of EIF4EBP1 protein]
Acetylcysteine inhibits the reaction [frenolicin B results in decreased phosphorylation of EIF4EBP1 protein]
Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of EIF4EBP1 protein]; Acetylcysteine inhibits the reaction [Polystyrenes analog results in increased phosphorylation of EIF4EBP1 protein]

PMID:21195169 PMID:24299490 PMID:26804764 PMID:30661989 PMID:36709824

NCBI chr16:64,792,595...64,805,984
Ensembl chr16:64,790,226...64,805,984

G

elastin microfibril interfacer 2

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of EMILIN2 mRNA

NCBI chr 9:111,160,708...111,220,463
Ensembl chr 9:111,160,712...111,220,352

G

endonuclease G

multiple interactions

[Glucose deficiency co-treated with Acetylcysteine] affects the localization of ENDOG protein; Acetylcysteine inhibits the reaction [perfosfamide results in increased localization of ENDOG protein]

PMID:17309078 PMID:18034189

NCBI chr 3:13,449,113...13,451,715
Ensembl chr 3:13,449,086...13,451,932

G

endoglin

increases expression

Acetylcysteine results in increased expression of ENG mRNA; Acetylcysteine results in increased expression of ENG protein

NCBI chr 3:15,934,566...15,972,618
Ensembl chr 3:15,934,518...15,973,230

G

ectonucleotide pyrophosphatase/phosphodiesterase 2

multiple interactions

Acetylcysteine inhibits the reaction [Toluene 2,4-Diisocyanate results in increased secretion of ENPP2 protein]

NCBI chr 7:86,202,345...86,325,050
Ensembl chr 7:86,202,350...86,324,827

G

ectonucleotide pyrophosphatase/phosphodiesterase 7

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of ENPP7 mRNA

NCBI chr10:104,242,169...104,247,185
Ensembl chr10:104,242,223...104,246,589

G

endosomal transmembrane epsin interactor 1

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of ENTREP1 mRNA

NCBI chr 1:221,592,500...221,646,603
Ensembl chr 1:221,592,503...221,646,758

G

E1A binding protein p300

multiple interactions

Acetylcysteine inhibits the reaction [IL1B promotes the reaction [EP300 protein binds to RELA protein]]

NCBI chr 7:113,108,476...113,178,529
Ensembl chr 7:113,106,247...113,136,088
Ensembl chr 7:113,106,247...113,136,088

G

endothelial PAS domain protein 1

multiple interactions

Acetylcysteine inhibits the reaction [cobaltous chloride results in increased expression of EPAS1 protein]; Acetylcysteine inhibits the reaction [Oxygen deficiency results in increased expression of EPAS1 protein]

NCBI chr 6:7,790,236...7,871,717
Ensembl chr 6:7,790,647...7,871,228

G

erythrocyte membrane protein band 4.1

multiple interactions

[Acetylcysteine co-treated with Atorvastatin] inhibits the reaction [sodium arsenite results in decreased expression of EPB41 protein]

NCBI chr 5:144,110,010...144,264,037
Ensembl chr 5:144,111,906...144,237,821

G

Eph receptor B1

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of EPHB1 mRNA

NCBI chr 8:102,507,549...102,944,839
Ensembl chr 8:102,507,549...102,944,839

G

EGFR pathway substrate 8, signaling adaptor

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of EPS8 mRNA

NCBI chr 4:170,388,378...170,486,873
Ensembl chr 4:170,388,378...170,486,873

G

ERCC excision repair 1, endonuclease non-catalytic subunit

multiple interactions

Acetylcysteine inhibits the reaction [Acetaminophen results in increased expression of ERCC1 mRNA]

NCBI chr 1:78,971,310...79,007,963
Ensembl chr 1:78,996,390...79,007,963

G

ERCC excision repair 8, CSA ubiquitin ligase complex subunit

multiple interactions

Acetylcysteine inhibits the reaction [dicrotophos results in decreased expression of ERCC8 protein]

NCBI chr 2:39,647,393...39,686,229
Ensembl chr 2:39,647,452...39,684,859

G

endoplasmic reticulum to nucleus signaling 1

multiple interactions
decreases phosphorylation

Acetylcysteine inhibits the reaction [gadolinium chloride results in increased expression of ERN1 protein]; Acetylcysteine inhibits the reaction [Sodium Fluoride results in increased expression of ERN1 mRNA]; Acetylcysteine inhibits the reaction [Sodium Fluoride results in increased phosphorylation of ERN1 protein]
Acetylcysteine results in decreased phosphorylation of ERN1 protein
Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased phosphorylation of ERN1 protein]; Acetylcysteine inhibits the reaction [chloroacetic acid results in increased phosphorylation of ERN1 protein]; Acetylcysteine inhibits the reaction [methylmercuric chloride results in increased expression of ERN1 protein modified form]; Acetylcysteine inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased phosphorylation of ERN1 protein]
Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased phosphorylation of ERN1 protein]; Acetylcysteine inhibits the reaction [Benomyl results in increased expression of ERN1 protein]; Acetylcysteine inhibits the reaction [tert-Butylhydroperoxide promotes the reaction [ERN1 protein binds to TRAF2 protein]]

PMID:21198628 PMID:24394546 PMID:25451595 PMID:27784618 PMID:29373603 More...

NCBI chr10:91,326,889...91,421,201
Ensembl chr10:91,330,654...91,421,029

G

estrogen receptor 1

multiple interactions

Acetylcysteine inhibits the reaction [Benzo(a)pyrene results in decreased expression of ESR1 protein]; Acetylcysteine inhibits the reaction [SOD2 protein affects the expression of ESR1 mRNA]
Acetylcysteine inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in decreased expression of ESR1 protein]

PMID:18829485 PMID:26149760 PMID:32402895

NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002

G

estrogen receptor 2

multiple interactions

Acetylcysteine inhibits the reaction [SOD2 protein affects the expression of ESR2 mRNA]

NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919

G

estrogen related receptor, alpha

multiple interactions

Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in decreased expression of ESRRA protein]

NCBI chr 1:204,104,100...204,114,182
Ensembl chr 1:204,104,101...204,114,268

G

ETS proto-oncogene 1, transcription factor

multiple interactions

Acetylcysteine inhibits the reaction [benz(a)anthracene results in increased expression of ETS1 mRNA]; Acetylcysteine inhibits the reaction [benzo(k)fluoranthene results in increased expression of ETS1 mRNA]; Acetylcysteine inhibits the reaction [indeno(1,2,3-cd)pyrene results in increased expression of ETS1 mRNA]

NCBI chr 8:31,045,909...31,168,010
Ensembl chr 8:31,045,945...31,168,010

G

enhancer of zeste 2 polycomb repressive complex 2 subunit

multiple interactions

Acetylcysteine inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] inhibits the reaction [EZH2 protein binds to CDKN2A promoter]]; Acetylcysteine inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] which results in decreased expression of EZH2 protein]; Acetylcysteine inhibits the reaction [Arsenic analog results in increased phosphorylation of EZH2 protein]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide affects the localization of EZH2 protein]

PMID:24582688 PMID:31551408

NCBI chr 4:76,624,399...76,687,362
Ensembl chr 4:76,624,399...76,687,362

G

coagulation factor XIII A1 chain

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of F13A1 mRNA

NCBI chr17:27,815,723...27,992,494
Ensembl chr17:27,815,702...27,992,700

G

coagulation factor III, tissue factor

multiple interactions

Acetylcysteine inhibits the reaction [Norepinephrine results in increased expression of F3 mRNA]

NCBI chr 2:209,827,061...209,838,666
Ensembl chr 2:209,826,959...209,838,668

G

fatty acid binding protein 4

multiple interactions

Acetylcysteine inhibits the reaction [INS1 protein results in increased expression of FABP4 protein]

NCBI chr 2:91,580,879...91,585,567
Ensembl chr 2:91,580,885...91,585,578

G

Fas associated via death domain

multiple interactions

[Acetylcysteine co-treated with Atorvastatin] inhibits the reaction [sodium arsenite results in increased expression of FADD protein]
[Acetylcysteine results in decreased abundance of Reactive Oxygen Species] inhibits the reaction [Lipopolysaccharides promotes the reaction [Polystyrenes results in decreased expression of FADD mRNA]]; [Acetylcysteine results in decreased abundance of Reactive Oxygen Species] inhibits the reaction [Lipopolysaccharides promotes the reaction [Polystyrenes results in decreased expression of FADD protein]]; [Acetylcysteine results in decreased abundance of Reactive Oxygen Species] inhibits the reaction [Polystyrenes promotes the reaction [Lipopolysaccharides results in decreased expression of FADD mRNA]]; [Acetylcysteine results in decreased abundance of Reactive Oxygen Species] inhibits the reaction [Polystyrenes promotes the reaction [Lipopolysaccharides results in decreased expression of FADD protein]]

PMID:20946910 PMID:35833596

NCBI chr 1:199,743,200...199,745,746
Ensembl chr 1:199,739,994...199,745,653

G

fatty acid desaturase 2

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of FADS2 mRNA

NCBI chr 1:206,707,384...206,747,333
Ensembl chr 1:206,708,783...206,748,789

G

family with sequence similarity 114, member A1

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of FAM114A1 mRNA

NCBI chr14:43,275,693...43,346,154
Ensembl chr14:43,275,701...43,346,174

G

family with sequence similarity 114, member A2

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of FAM114A2 mRNA

NCBI chr10:41,661,787...41,696,790
Ensembl chr10:41,661,787...41,696,741

G

family with sequence similarity 13, member A

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of FAM13A mRNA

NCBI chr 4:88,056,521...88,155,782
Ensembl chr 4:88,058,403...88,155,860

G

family with sequence similarity 186 member A

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of FAM186A mRNA

NCBI chr 7:131,043,586...131,102,312

G

fatty acyl CoA reductase 1

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of FAR1 mRNA

NCBI chr 1:167,644,622...167,705,868
Ensembl chr 1:167,644,677...167,705,730

G

Fas cell surface death receptor

multiple interactions
increases expression

Acetylcysteine inhibits the reaction [Cholesterol analog results in increased expression of FAS mRNA]
Acetylcysteine results in increased expression of FAS mRNA
Acetylcysteine inhibits the reaction [2'-(4-chlorophenyl)-3-(4-chlorophenylidene)-5,10-dimethyl-12-methylene-decahydro-1,2-(1',3'-dioxocyclopenta(c))azuleno(4,5-b)furan-4,11-dione results in decreased expression of FAS protein]; Acetylcysteine inhibits the reaction [[Heterocyclic Compounds binds to Thiazoles] which results in increased expression of FAS protein]; Acetylcysteine inhibits the reaction [Arachidonic Acid results in increased expression of FAS protein]; Acetylcysteine inhibits the reaction [arsenic trioxide results in increased expression of FAS protein]; Acetylcysteine inhibits the reaction [Biological Products results in increased expression of FAS protein]; Acetylcysteine inhibits the reaction [cadmium acetate results in increased expression of FAS protein]

PMID:9227460 PMID:15382040 PMID:16169029 PMID:19014919 PMID:19477266 More...

NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591

G

Fas ligand

multiple interactions
increases expression

[Acetylcysteine results in decreased abundance of Reactive Oxygen Species] which results in decreased expression of FASLG mRNA; Acetylcysteine inhibits the reaction [[Cisplatin co-treated with FASLG protein] results in decreased expression of BID protein]; Acetylcysteine inhibits the reaction [[Cisplatin co-treated with FASLG protein] results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [[Cisplatin co-treated with FASLG protein] results in increased activity of CASP8 protein]; Acetylcysteine inhibits the reaction [[Cisplatin co-treated with FASLG protein] results in increased activity of CASP9 protein]; Acetylcysteine inhibits the reaction [Arachidonic Acid results in increased expression of FASLG protein]; Acetylcysteine inhibits the reaction [Biological Products results in increased expression of FASLG protein]
Acetylcysteine results in increased expression of FASLG mRNA
[Atorvastatin co-treated with Acetylcysteine] inhibits the reaction [sodium arsenite results in increased expression of FASLG protein]; Acetylcysteine inhibits the reaction [beta-hexachlorocyclohexane results in increased expression of FASLG protein]; Acetylcysteine inhibits the reaction [Dichlorodiphenyl Dichloroethylene results in increased expression of FASLG mRNA]; Acetylcysteine inhibits the reaction [Dichlorodiphenyl Dichloroethylene results in increased expression of FASLG protein]
Acetylcysteine inhibits the reaction [Azoxymethane results in increased expression of FASLG protein]; Acetylcysteine inhibits the reaction [Zinc results in increased expression of FASLG protein]

PMID:11864783 PMID:17574045 PMID:19644561 PMID:19720122 PMID:19760616 More...

NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215

G

F-box protein 32

multiple interactions

Acetylcysteine inhibits the reaction [Indican results in increased expression of FBXO32 protein]

NCBI chr 7:89,731,428...89,764,997
Ensembl chr 7:89,730,232...89,765,436

G

flap structure-specific endonuclease 1

multiple interactions

Acetylcysteine inhibits the reaction [Acetaminophen results in increased expression of FEN1 mRNA]

NCBI chr 1:206,845,126...206,849,821
Ensembl chr 1:206,844,884...206,850,003

G

fer-1-like family member 5

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of FER1L5 mRNA

NCBI chr 9:38,605,835...38,661,869
Ensembl chr 9:38,607,843...38,660,425

G

fibroblast growth factor 12

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of FGF12 mRNA

NCBI chr11:71,997,151...72,564,757
Ensembl chr11:71,997,099...72,562,607

G

fibroblast growth factor 2

decreases expression
multiple interactions

Acetylcysteine results in decreased expression of FGF2 mRNA
Acetylcysteine inhibits the reaction [hydroxyethyl methacrylate results in increased secretion of FGF2 protein]

PMID:16084531 PMID:19176594

NCBI chr 2:120,236,328...120,290,673
Ensembl chr 2:120,236,328...120,291,221

G

fibroblast growth factor 21

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of FGF21 mRNA; Acetylcysteine inhibits the reaction [[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of FGF21 mRNA]
Acetylcysteine inhibits the reaction [cobaltous chloride results in decreased expression of FGF21 mRNA]; Acetylcysteine inhibits the reaction [cobaltous chloride results in decreased secretion of FGF21 protein]

PMID:22129741 PMID:22917661

NCBI chr 1:96,083,360...96,084,911
Ensembl chr 1:96,083,441...96,090,454

G

fibroblast growth factor 6

multiple interactions

Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of and results in increased secretion of FGF6 protein]

NCBI chr 4:159,854,913...159,863,447
Ensembl chr 4:159,854,913...159,863,447

G

fibroblast growth factor 7

multiple interactions

Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of and results in increased secretion of FGF7 protein]

NCBI chr 3:113,280,448...113,333,279
Ensembl chr 3:113,281,283...113,332,929

G

fragile histidine triad diadenosine triphosphatase

multiple interactions

Acetylcysteine inhibits the reaction [Tobacco Smoke Pollution results in decreased expression of FHIT protein]

NCBI chr15:13,935,029...15,442,620
Ensembl chr15:13,934,995...15,442,340

G

filamin A interacting protein 1-like

decreases expression

Acetylcysteine results in decreased expression of FILIP1L mRNA

NCBI chr11:42,937,353...43,177,085
Ensembl chr11:42,940,467...43,177,415

G

fission, mitochondrial 1

multiple interactions

Acetylcysteine inhibits the reaction [Polystyrenes analog results in decreased expression of FIS1 protein]
Acetylcysteine inhibits the reaction [Doxorubicin results in increased expression of FIS1 protein]

PMID:37084995 PMID:37499777

NCBI chr12:19,708,560...19,723,392
Ensembl chr12:19,708,558...19,723,377

G

FKBP prolyl isomerase 5

multiple interactions

Acetylcysteine inhibits the reaction [SOD2 protein affects the expression of FKBP5 mRNA]

NCBI chr20:6,457,207...6,575,404
Ensembl chr20:6,457,216...6,541,674

G

filaggrin

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of FLG mRNA

NCBI chr 2:178,884,793...178,912,986

G

filamin A

multiple interactions

Acetylcysteine inhibits the reaction [arsenic trichloride results in increased phosphorylation of FLNA protein]

NCBI chr X:152,007,758...152,034,266
Ensembl chr X:152,007,758...152,031,052

G

Fms related receptor tyrosine kinase 1

increases expression
multiple interactions

Acetylcysteine results in increased expression of FLT1 protein
Acetylcysteine inhibits the reaction [Cadmium results in increased expression of FLT1 mRNA]; Acetylcysteine inhibits the reaction [Water Pollutants, Chemical results in increased expression of FLT1 mRNA]

PMID:17992120 PMID:29408318

NCBI chr12:7,296,899...7,468,626
Ensembl chr12:7,297,292...7,468,626

G

Fms related receptor tyrosine kinase 3 ligand

multiple interactions

Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of and results in increased secretion of FLT3LG protein]

NCBI chr 1:95,615,056...95,620,463
Ensembl chr 1:95,609,370...95,620,463

G

fragile X messenger ribonucleoprotein 1

multiple interactions

Acetylcysteine promotes the reaction [FMR1 5' UTR mutant form results in decreased activity of CS protein]

NCBI chr X:147,240,239...147,278,057
Ensembl chr X:147,240,301...147,278,050

G

fibronectin 1

multiple interactions

Acetylcysteine inhibits the reaction [Glucose results in increased expression of FN1 protein]
Acetylcysteine inhibits the reaction [FN1 protein modified form results in increased expression of and results in increased secretion of MMP10 protein]; Acetylcysteine inhibits the reaction [FN1 protein modified form results in increased expression of and results in increased secretion of MMP13 protein]; Acetylcysteine inhibits the reaction [FN1 protein modified form results in increased expression of and results in increased secretion of MMP3 protein]; Acetylcysteine inhibits the reaction [nickel chloride results in increased expression of FN1 protein]; Acetylcysteine inhibits the reaction [TNF protein results in increased expression of and results in increased secretion of FN1 protein]; Acetylcysteine inhibits the reaction [TNF protein results in increased expression of FN1 mRNA]

PMID:16632126 PMID:17395008 PMID:22245600 PMID:22648416

NCBI chr 9:73,196,044...73,264,695
Ensembl chr 9:73,196,044...73,264,678

G

Fos proto-oncogene, AP-1 transcription factor subunit

multiple interactions
decreases activity

Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of FOS]; Acetylcysteine inhibits the reaction [Etoposide results in increased expression of FOS]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased activity of FOS protein]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased expression of FOS mRNA]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased expression of FOS]; Acetylcysteine inhibits the reaction [sodium arsenite results in increased expression of FOS protein]; Acetylcysteine inhibits the reaction [xanthatin results in increased expression of FOS]
Acetylcysteine results in decreased activity of FOS protein
Acetylcysteine inhibits the reaction [[indole-3-carbinol co-treated with Diethylnitrosamine] results in decreased expression of FOS mRNA]; Acetylcysteine inhibits the reaction [Asbestos, Crocidolite results in increased expression of FOS mRNA]; Acetylcysteine inhibits the reaction [Carbon Tetrachloride results in increased expression of FOS mRNA]; Acetylcysteine inhibits the reaction [methylmercuric chloride results in increased expression of and results in increased phosphorylation of FOS protein]; Acetylcysteine promotes the reaction [bis(maltolato)oxovanadium(IV) results in decreased activity of [FOS protein binds to JUN protein]]
Acetylcysteine inhibits the reaction [Asbestos, Crocidolite results in increased expression of FOS mRNA]; Acetylcysteine inhibits the reaction [chromium hexavalent ion results in increased expression of FOS protein]; Acetylcysteine inhibits the reaction [oxaliplatin results in increased expression of FOS protein]; Acetylcysteine inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of [FOS protein co-treated with JUN protein]]; Acetylcysteine inhibits the reaction [Tobacco Smoke Pollution results in increased expression of FOS mRNA]

PMID:7743507 PMID:8825185 PMID:8853906 PMID:9043100 PMID:9525474 More...

NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036

G

FOS like 1, AP-1 transcription factor subunit

multiple interactions

Acetylcysteine inhibits the reaction [Asbestos, Crocidolite results in increased expression of FOSL1 mRNA]
Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of FOSL1 mRNA]

PMID:15520183 PMID:19010381

NCBI chr 1:202,754,549...202,763,057
Ensembl chr 1:202,754,529...202,764,930

G

forkhead box D2

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of FOXD2 mRNA

NCBI chr 5:128,427,986...128,430,709
Ensembl chr 5:128,429,020...128,430,504

G

forkhead box D4

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of FOXD4 mRNA

NCBI chr 1:222,557,494...222,559,189
Ensembl chr 1:222,557,360...222,559,159

G

forkhead box M1

multiple interactions

Acetylcysteine inhibits the reaction [Thiostrepton results in decreased expression of FOXM1 protein]

NCBI chr 4:161,639,538...161,652,012
Ensembl chr 4:161,638,816...161,650,684

G

forkhead box O1

multiple interactions

Acetylcysteine inhibits the reaction [Cyclosporine results in increased expression of and affects the localization of FOXO1 protein modified form]; Acetylcysteine inhibits the reaction [Glucose affects the localization of FOXO1 protein]

PMID:23765110 PMID:33450223

NCBI chr 2:136,312,168...136,390,603
Ensembl chr 2:136,312,168...136,387,790

G

forkhead box O3

multiple interactions

Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of FOXO3 protein]; Acetylcysteine inhibits the reaction [Simvastatin results in increased phosphorylation of FOXO3 protein]
Acetylcysteine inhibits the reaction [tomentosin results in increased expression of FOXO3 protein]
Acetylcysteine inhibits the reaction [Doxorubicin results in decreased expression of FOXO3 protein]; Acetylcysteine inhibits the reaction [Glucose results in decreased phosphorylation of FOXO3 protein]; Acetylcysteine inhibits the reaction [Glucose results in increased phosphorylation of FOXO3 protein]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in decreased expression of FOXO3 protein]

PMID:20883752 PMID:23159718 PMID:25471227 PMID:30104959 PMID:30917517 More...

NCBI chr20:45,669,708...45,764,606
Ensembl chr20:45,672,995...45,764,561

G

forkhead box P3

multiple interactions

Acetylcysteine inhibits the reaction [dorsomorphin results in decreased expression of FOXP3 protein]

NCBI chr X:14,908,494...14,924,994
Ensembl chr X:14,908,494...14,923,838

G

follicle stimulating hormone subunit beta

multiple interactions

Acetylcysteine inhibits the reaction [Sodium Fluoride results in increased expression of FSHB protein]

NCBI chr 3:93,548,560...93,552,370
Ensembl chr 3:93,548,560...93,552,370

G

ferritin heavy chain 1

multiple interactions

Acetylcysteine inhibits the reaction [Rotenone results in increased expression of FTH1 mRNA]
Acetylcysteine inhibits the reaction [di-n-propyldithiocarbamate results in decreased expression of FTH1 protein]

PMID:18325346 PMID:32687844

NCBI chr 1:206,627,142...206,629,430
Ensembl chr 1:206,627,103...206,725,424

G

ferritin light chain 1

multiple interactions

Acetylcysteine inhibits the reaction [arsenite results in increased expression of FTL1 protein]

NCBI chr 1:95,936,387...95,938,234
Ensembl chr 1:95,936,387...95,939,725
Ensembl chr10:95,936,387...95,939,725

G

FTO, alpha-ketoglutarate dependent dioxygenase

multiple interactions

Acetylcysteine inhibits the reaction [sodium arsenite results in increased expression of FTO mRNA]
Acetylcysteine inhibits the reaction [Paraquat results in decreased expression of FTO mRNA]

PMID:31004932 PMID:34425375

NCBI chr19:15,284,898...15,692,142
Ensembl chr19:15,349,696...15,692,083

G

frataxin

affects response to substance
multiple interactions

Acetylcysteine affects the susceptibility to FXN protein mutant form
Acetylcysteine affects the reaction [Ethanol affects the expression of FXN protein]

PMID:16120311 PMID:33017621

NCBI chr 1:221,874,007...221,897,543
Ensembl chr 1:221,872,420...221,897,540

G

FYN proto-oncogene, Src family tyrosine kinase

multiple interactions

Acetylcysteine inhibits the reaction [chromium hexavalent ion results in increased activity of FYN protein]
Acetylcysteine inhibits the reaction [cobaltous chloride results in increased phosphorylation of FYN protein]

PMID:12902192 PMID:20850416

NCBI chr20:42,767,733...42,960,903
Ensembl chr20:42,766,369...42,959,911

G

glucose-6-phosphatase catalytic subunit 1

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of G6PC1 mRNA

NCBI chr10:86,307,400...86,318,766
Ensembl chr10:86,257,668...86,333,804

G

glucose-6-phosphate dehydrogenase

multiple interactions
increases activity

Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of G6PD mRNA]; Acetylcysteine inhibits the reaction [Oxygen deficiency results in increased expression of G6PD mRNA]
Acetylcysteine results in increased activity of G6PD protein

PMID:3099627 PMID:12717738 PMID:15225644

NCBI chr X:152,201,081...152,220,863
Ensembl chr X:152,201,098...152,220,801

G

growth arrest and DNA-damage-inducible, alpha

multiple interactions
decreases expression
increases expression

Acetylcysteine inhibits the reaction [Formaldehyde results in increased expression of GADD45A mRNA]; Acetylcysteine inhibits the reaction [raspberry ketone results in increased expression of GADD45A mRNA]; Acetylcysteine inhibits the reaction [rhododendrol results in increased expression of GADD45A mRNA]; Acetylcysteine inhibits the reaction [Vehicle Emissions results in increased expression of GADD45A mRNA]
Acetylcysteine results in decreased expression of GADD45A mRNA
Acetylcysteine results in increased expression of GADD45A mRNA
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of GADD45A mRNA; Acetylcysteine inhibits the reaction [4-hydroxy-2-nonenal results in increased expression of GADD45A mRNA]

PMID:18849615 PMID:22129741 PMID:24291486 PMID:26332274 PMID:26867644

NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115

G

growth arrest and DNA-damage-inducible, gamma

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of GADD45G mRNA
Acetylcysteine inhibits the reaction [[xanthatin results in increased expression of GADD45G mRNA] which results in increased abundance of Reactive Oxygen Species]; Acetylcysteine inhibits the reaction [xanthatin results in increased expression of GADD45G mRNA]; Acetylcysteine inhibits the reaction [xanthatin results in increased expression of GADD45G protein]

PMID:22129741 PMID:23313378

NCBI chr17:13,376,842...13,378,587
Ensembl chr17:13,376,839...13,378,610

G

polypeptide N-acetylgalactosaminyltransferase-like 5

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of GALNTL5 mRNA

NCBI chr 4:9,873,426...9,923,297
Ensembl chr 4:9,873,428...9,923,136

G

growth associated protein 43

multiple interactions

Acetylcysteine inhibits the reaction [cobaltous chloride results in increased phosphorylation of GAP43 protein]

NCBI chr11:58,376,371...58,470,047
Ensembl chr11:58,376,371...58,470,045

G

glyceraldehyde-3-phosphate dehydrogenase

decreases expression
multiple interactions

Acetylcysteine results in decreased expression of GAPDH mRNA
Acetylcysteine inhibits the reaction [arsenite results in decreased expression of GAPDH protein]

PMID:11108245 PMID:15175009

NCBI chr 4:157,962,312...157,967,158
Ensembl chr 4:157,962,343...157,966,235

G

GATA binding protein 1

multiple interactions

Acetylcysteine inhibits the reaction [Aclarubicin results in increased expression of GATA1 mRNA]; Acetylcysteine inhibits the reaction [Butyric Acid results in increased expression of GATA1 mRNA]

NCBI chr X:14,529,706...14,537,530
Ensembl chr X:14,529,702...14,537,530

G

guanylate binding protein 1

decreases expression

Acetylcysteine results in decreased expression of GBP1 mRNA

NCBI chr 2:231,398,136...231,432,773
Ensembl chr 2:231,398,163...231,432,131
Ensembl chr 2:231,398,163...231,432,131

G

glutamate-cysteine ligase, catalytic subunit

multiple interactions

Acetylcysteine inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of GCLC protein]; Acetylcysteine inhibits the reaction [3-O-caffeoyl-1-methylquinic acid results in increased expression of GCLC mRNA]; Acetylcysteine inhibits the reaction [Dichlorodiphenyl Dichloroethylene results in decreased expression of GCLC mRNA]; Acetylcysteine inhibits the reaction [Dichlorodiphenyl Dichloroethylene results in decreased expression of GCLC protein]; Acetylcysteine inhibits the reaction [Hydrocarbons, Chlorinated analog results in increased expression of GCLC protein]; Acetylcysteine inhibits the reaction [Indomethacin results in increased expression of GCLC mRNA]; Acetylcysteine inhibits the reaction [Paraquat results in decreased expression of GCLC protein]; Acetylcysteine inhibits the reaction [Sulindac results in increased expression of GCLC protein]; Acetylcysteine inhibits the reaction [tetrabromobisphenol A results in increased expression of GCLC mRNA]
Acetylcysteine inhibits the reaction [decamethrin results in increased expression of GCLC mRNA]; Acetylcysteine inhibits the reaction [decamethrin results in increased expression of GCLC protein]
Acetylcysteine inhibits the reaction [2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone results in increased expression of GCLC mRNA]; Acetylcysteine inhibits the reaction [6-formylindolo(3,2-b)carbazole results in increased expression of GCLC mRNA]; Acetylcysteine inhibits the reaction [arsenite results in increased expression of GCLC mRNA]; Acetylcysteine inhibits the reaction [Buthionine Sulfoximine results in increased expression of GCLC mRNA]; Acetylcysteine inhibits the reaction [Hypochlorous Acid results in increased expression of GCLC mRNA]

PMID:11820781 PMID:11909699 PMID:16631525 PMID:17540521 PMID:17980396 More...

NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544

G

glutamate cysteine ligase, modifier subunit

multiple interactions
affects response to substance

Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of GCLM mRNA]; Acetylcysteine inhibits the reaction [elesclomol results in increased expression of GCLM mRNA]
GCLM protein affects the susceptibility to Acetylcysteine
Acetylcysteine inhibits the reaction [arsenite results in increased expression of GCLM mRNA]

PMID:17584759 PMID:18723479 PMID:19328227 PMID:19350554

NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535

G

growth differentiation factor 1

multiple interactions

Acetylcysteine inhibits the reaction [sodium arsenite results in decreased expression of GDF1 protein]
Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in decreased expression of GDF1 protein]; Acetylcysteine inhibits the reaction [sodium arsenite results in decreased expression of GDF1 protein]

NCBI chr16:19,097,309...19,112,519
Ensembl chr16:19,097,314...19,112,519

G

growth differentiation factor 15

multiple interactions

Acetylcysteine inhibits the reaction [Buthionine Sulfoximine results in increased expression of GDF15 mRNA]

NCBI chr16:18,804,457...18,808,043
Ensembl chr16:18,805,239...18,808,055

G

glial cell derived neurotrophic factor

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of GDNF mRNA
Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of GDNF protein]

PMID:22129741 PMID:26138014

NCBI chr 2:56,894,022...56,919,935
Ensembl chr 2:56,895,010...56,917,209

G

glial fibrillary acidic protein

multiple interactions

Acetylcysteine inhibits the reaction [Streptozocin results in decreased expression of GFAP protein]
Acetylcysteine inhibits the reaction [Fenitrothion results in increased expression of GFAP protein]

PMID:28499986 PMID:31173782

NCBI chr10:87,852,891...87,861,631
Ensembl chr10:87,852,890...87,861,589

G

gamma-glutamyltransferase 1

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in increased expression of GGT1 mRNA; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased secretion of GGT1 protein]; Acetylcysteine inhibits the reaction [Mercuric Chloride results in increased expression of GGT1 protein]; Acetylcysteine inhibits the reaction [Risperidone results in increased expression of and results in increased secretion of GGT1 protein]; Acetylcysteine inhibits the reaction [Vitamin K 3 results in increased activity of GGT1 protein]; Acetylcysteine promotes the reaction [Selenium inhibits the reaction [Mercuric Chloride results in increased expression of GGT1 protein]]; Selenium promotes the reaction [Acetylcysteine inhibits the reaction [Mercuric Chloride results in increased expression of GGT1 protein]]

PMID:12030384 PMID:22129741 PMID:24485406 PMID:24634002 PMID:27387968

NCBI chr20:13,074,695...13,104,095
Ensembl chr20:13,074,700...13,108,442

G

gap junction protein, alpha 1

multiple interactions

Acetylcysteine inhibits the reaction [Glyphosate results in decreased expression of GJA1 protein]

NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582

G

gap junction protein, alpha 4

decreases expression

Acetylcysteine results in decreased expression of GJA4 mRNA

NCBI chr 5:139,633,324...139,635,857
Ensembl chr 5:139,633,287...139,635,925

G

gap junction protein, beta 1

multiple interactions

Acetylcysteine inhibits the reaction [2-chloroethyl ethyl sulfide results in decreased expression of GJB1 mRNA]

NCBI chr X:66,501,848...66,509,783
Ensembl chr X:66,501,820...66,509,925

G

glycerol kinase

multiple interactions

Acetylcysteine inhibits the reaction [Malathion results in increased activity of GK protein]

NCBI chr X:50,162,089...50,238,707
Ensembl chr X:50,163,123...50,238,631

G

gastrokine 2

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of GKN2 mRNA

NCBI chr 4:119,778,326...119,824,366
Ensembl chr 4:119,818,280...119,824,363

G

galactosidase, beta 1

multiple interactions

Acetylcysteine inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] which results in increased activity of GLB1 protein]; Acetylcysteine inhibits the reaction [lopinavir-ritonavir drug combination results in increased activity of GLB1 protein]; Acetylcysteine inhibits the reaction [Ritonavir results in increased activity of GLB1 protein]

PMID:20884875 PMID:31551408

NCBI chr 8:114,085,508...114,158,127
Ensembl chr 8:114,085,508...114,158,127

G

glucocorticoid induced 1

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of GLCCI1 mRNA

NCBI chr 4:36,307,956...36,635,614
Ensembl chr 4:36,307,903...36,635,612

G

glucagon-like peptide 1 receptor

multiple interactions

Acetylcysteine inhibits the reaction [Oleic Acid results in increased degradation of and results in decreased expression of GLP1R protein]

NCBI chr20:8,972,004...9,010,241
Ensembl chr20:8,972,004...9,010,241

G

glutaredoxin

affects response to substance

GLRX protein affects the susceptibility to Acetylcysteine

NCBI chr 2:5,341,873...5,351,686
Ensembl chr 2:5,341,885...5,351,680

G

glutamate dehydrogenase 1

multiple interactions

Acetylcysteine inhibits the reaction [epigallocatechin gallate results in decreased expression of GLUD1 mRNA]

NCBI chr16:9,640,312...9,673,961
Ensembl chr16:9,640,312...9,673,957

G

G protein subunit alpha i2

multiple interactions

Acetylcysteine affects the reaction [IER3 protein affects the expression of GNAI2 mRNA]
Acetylcysteine inhibits the reaction [Glucose results in decreased expression of GNAI2 protein]; Acetylcysteine inhibits the reaction [Streptozocin results in decreased expression of GNAI2 protein]

PMID:18441196 PMID:20713914

NCBI chr 8:108,288,401...108,309,009
Ensembl chr 8:108,288,401...108,308,979

G

G protein subunit alpha i3

multiple interactions

Acetylcysteine inhibits the reaction [Glucose results in decreased expression of GNAI3 protein]; Acetylcysteine inhibits the reaction [Streptozocin results in decreased expression of GNAI3 protein]

NCBI chr 2:195,742,765...195,780,720
Ensembl chr 2:195,742,642...195,780,742

G

glutamic-oxaloacetic transaminase 1

multiple interactions

Acetylcysteine inhibits the reaction [Risperidone results in increased expression of and results in increased secretion of GOT1 protein]

NCBI chr 1:242,357,293...242,381,535
Ensembl chr 1:242,357,306...242,380,633

G

glycoprotein Ib platelet subunit alpha

multiple interactions

Acetylcysteine inhibits the reaction [THPO protein results in increased expression of GP1BA protein]

NCBI chr10:55,352,938...55,355,804
Ensembl chr10:55,352,899...55,356,774

G

glycoprotein 2

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of GP2 mRNA

NCBI chr 1:173,797,057...173,812,619
Ensembl chr 1:173,797,057...173,812,619

G

G protein-coupled bile acid receptor 1

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of GPBAR1 mRNA

NCBI chr 9:75,860,758...75,863,260
Ensembl chr 9:75,860,677...75,863,168

G

glypican 5

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of GPC5 mRNA; Acetylcysteine inhibits the reaction [[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of GPC5 mRNA]

NCBI chr15:92,207,275...93,644,054
Ensembl chr15:92,239,176...93,643,282

G

G protein-coupled receptor 153

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of GPR153 mRNA

NCBI chr 5:162,781,587...162,792,975
Ensembl chr 5:162,781,587...162,792,971

G

G protein-coupled receptor 20

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of GPR20 mRNA

NCBI chr 7:105,601,761...105,611,959
Ensembl chr 7:105,602,368...105,603,430

G

G protein-coupled receptor 55

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of GPR55 mRNA; Acetylcysteine inhibits the reaction [[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of GPR55 mRNA]

NCBI chr 9:86,584,906...86,640,601
Ensembl chr 9:86,590,885...86,640,613

G

glutamic--pyruvic transaminase

multiple interactions

Acetylcysteine inhibits the reaction [[Galactosamine co-treated with lipopolysaccharide, E coli O55-B5] results in increased expression of GPT protein]; Acetylcysteine inhibits the reaction [Acetaminophen results in increased activity of GPT protein]; Acetylcysteine inhibits the reaction [Acetaminophen results in increased expression of GPT protein]; Acetylcysteine inhibits the reaction [Lipopolysaccharides promotes the reaction [PTEN gene mutant form results in increased secretion of GPT protein]]; IL22 protein promotes the reaction [Acetylcysteine inhibits the reaction [Acetaminophen results in increased expression of GPT protein]]
[Zinc co-treated with Selenium co-treated with Acetylcysteine] inhibits the reaction [dimethyl mercury results in increased activity of GPT protein]; Acetylcysteine inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased activity of GPT protein]; Acetylcysteine inhibits the reaction [Acetaminophen affects the activity of GPT protein]; Acetylcysteine inhibits the reaction [bisphenol A results in increased expression of GPT protein]; Acetylcysteine inhibits the reaction [Cyclosporine results in increased activity of GPT protein]; Acetylcysteine inhibits the reaction [Ethanol results in increased activity of GPT protein]; Acetylcysteine inhibits the reaction [Glyphosate results in increased activity of GPT protein]; Acetylcysteine inhibits the reaction [Mercuric Chloride results in increased activity of GPT protein]; Acetylcysteine inhibits the reaction [Risperidone results in increased expression of and results in increased secretion of GPT protein]; Selenium promotes the reaction [Acetylcysteine inhibits the reaction [Mercuric Chloride results in increased activity of GPT protein]]

PMID:17461432 PMID:20688495 PMID:20804811 PMID:23375450 PMID:24485406 More...

NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494

G

glutathione peroxidase 1

multiple interactions
increases expression

Acetylcysteine inhibits the reaction [pterostilbene results in increased expression of GPX1 mRNA]
Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in decreased expression of GPX1 protein]
Acetylcysteine results in increased expression of GPX1 protein
Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in decreased activity of GPX1 protein]; Acetylcysteine inhibits the reaction [mancozeb results in decreased expression of GPX1 mRNA]; Acetylcysteine inhibits the reaction [raspberry ketone results in decreased expression of GPX1 protein]; Acetylcysteine inhibits the reaction [rhododendrol results in decreased expression of GPX1 protein]

PMID:25341683 PMID:26867644 PMID:30037311 PMID:30104959 PMID:35112789

NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024

G

glutathione peroxidase 2

multiple interactions

Acetylcysteine inhibits the reaction [[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of GPX2 mRNA]

NCBI chr 6:95,493,589...95,496,877
Ensembl chr 6:95,493,589...95,496,877

G

glutathione peroxidase 4

multiple interactions

Acetylcysteine inhibits the reaction [sodium arsenite results in decreased expression of GPX4 mRNA]

NCBI chr 7:9,650,186...9,652,982
Ensembl chr 7:9,650,185...9,652,982

G

glutamate ionotropic receptor NMDA type subunit 2B

multiple interactions

Acetylcysteine inhibits the reaction [Pilocarpine results in increased expression of GRIN2B protein]

NCBI chr 4:168,580,824...169,044,110
Ensembl chr 4:168,599,546...169,042,279

G

glutamate metabotropic receptor 2

increases activity

Acetylcysteine results in increased activity of GRM2 protein

NCBI chr 8:107,280,099...107,293,159
Ensembl chr 8:107,280,099...107,293,146

G

glutamate metabotropic receptor 3

increases activity

Acetylcysteine results in increased activity of GRM3 protein

NCBI chr 4:24,364,854...24,643,972
Ensembl chr 4:24,365,115...24,609,804

G

glutamate metabotropic receptor 5

increases activity

Acetylcysteine results in increased activity of GRM5 protein

NCBI chr 1:141,310,069...141,884,980
Ensembl chr 1:141,312,368...141,882,274

G

gasdermin D

multiple interactions
increases expression

Acetylcysteine inhibits the reaction [hydroquinone results in increased expression of GSDMD protein]; Acetylcysteine inhibits the reaction [Lipopolysaccharides results in increased cleavage of GSDMD protein]; Acetylcysteine inhibits the reaction [saikosaponin D results in increased cleavage of GSDMD protein]; Acetylcysteine inhibits the reaction [tetrachlorobenzoquinone results in increased cleavage of GSDMD protein]; Quercetin promotes the reaction [Acetylcysteine inhibits the reaction [Lipopolysaccharides results in increased cleavage of GSDMD protein]]
Acetylcysteine results in increased expression of GSDMD protein
Acetylcysteine inhibits the reaction [cadmium acetate results in increased expression of GSDMD protein]
Acetylcysteine inhibits the reaction [Aluminum Chloride results in increased expression of GSDMD mRNA]; Acetylcysteine inhibits the reaction [Aluminum Chloride results in increased expression of GSDMD protein]

PMID:30378427 PMID:34791735 PMID:36347317 PMID:36354081 PMID:36646296 More...

NCBI chr 7:107,542,489...107,547,051
Ensembl chr 7:107,542,083...107,547,055

G

glycogen synthase kinase 3 beta

multiple interactions

Acetylcysteine inhibits the reaction [Cadmium results in increased phosphorylation of GSK3B protein]; Acetylcysteine inhibits the reaction [Chromium results in decreased phosphorylation of GSK3B protein]
[Acetylcysteine co-treated with Chlorpyrifos] results in increased activity of GSK3B protein; Acetylcysteine inhibits the reaction [27-hydroxycholesterol inhibits the reaction [GSK3B protein binds to CTNNB1 protein]]; Acetylcysteine inhibits the reaction [27-hydroxycholesterol inhibits the reaction [YWHAH protein binds to GSK3B protein]]; Acetylcysteine inhibits the reaction [27-hydroxycholesterol results in increased phosphorylation of GSK3B protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of GSK3B protein]; Acetylcysteine inhibits the reaction [DDT results in increased phosphorylation of GSK3B protein]; Acetylcysteine inhibits the reaction [Fenretinide results in increased phosphorylation of GSK3B protein]; Acetylcysteine inhibits the reaction [phenethyl isothiocyanate results in increased phosphorylation of GSK3B protein]

PMID:18569013 PMID:19126599 PMID:24968063 PMID:25246272 PMID:27658547 More...

NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646

G

glutathione-disulfide reductase

multiple interactions

Acetylcysteine inhibits the reaction [3-O-caffeoyl-1-methylquinic acid results in increased expression of GSR mRNA]; Acetylcysteine inhibits the reaction [tetrabromobisphenol A results in decreased expression of GSR mRNA]
Acetylcysteine inhibits the reaction [Acetaminophen results in decreased activity of GSR protein]
[Acetylcysteine co-treated with Paraquat co-treated with Maneb] results in increased activity of GSR protein; [Acetylcysteine co-treated with Paraquat] results in increased activity of GSR protein; Acetylcysteine inhibits the reaction [Arsenic Trioxide inhibits the reaction [GSR protein results in increased oxidation of NADP]]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in decreased activity of GSR protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of GSR mRNA]; Acetylcysteine inhibits the reaction [Dimethylnitrosamine results in decreased activity of GSR protein]; Acetylcysteine inhibits the reaction [Paraquat promotes the reaction [Zinc Sulfate results in decreased activity of GSR protein]]; Acetylcysteine inhibits the reaction [Paraquat results in decreased activity of GSR protein]; Acetylcysteine inhibits the reaction [Streptozocin results in decreased activity of GSR protein]; Acetylcysteine inhibits the reaction [tributyltin results in increased expression of GSR protein]; Acetylcysteine inhibits the reaction [Zinc Sulfate promotes the reaction [Paraquat results in decreased activity of GSR protein]]; Acetylcysteine inhibits the reaction [Zinc Sulfate results in decreased activity of GSR protein]; Acetylcysteine promotes the reaction [EUK-134 inhibits the reaction [Paraquat promotes the reaction [Zinc Sulfate results in decreased activity of GSR protein]]]; Acetylcysteine promotes the reaction [EUK-134 inhibits the reaction [Paraquat results in decreased activity of GSR protein]]; Acetylcysteine promotes the reaction [EUK-134 inhibits the reaction [Zinc Sulfate promotes the reaction [Paraquat results in decreased activity of GSR protein]]]; Acetylcysteine promotes the reaction [EUK-134 inhibits the reaction [Zinc Sulfate results in decreased activity of GSR protein]]; Acetylcysteine promotes the reaction [Zinc Sulfate inhibits the reaction [EUK-134 results in decreased activity of GSR protein]]; EUK-134 promotes the reaction [Acetylcysteine inhibits the reaction [Paraquat promotes the reaction [Zinc Sulfate results in decreased activity of GSR protein]]]; EUK-134 promotes the reaction [Acetylcysteine inhibits the reaction [Paraquat results in decreased activity of GSR protein]]; EUK-134 promotes the reaction [Acetylcysteine inhibits the reaction [Zinc Sulfate promotes the reaction [Paraquat results in decreased activity of GSR protein]]]; EUK-134 promotes the reaction [Acetylcysteine inhibits the reaction [Zinc Sulfate results in decreased activity of GSR protein]]

PMID:16631525 PMID:19840221 PMID:21114986 PMID:23159886 PMID:24634002 More...

NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661

G

glutathione S-transferase alpha 1

multiple interactions

Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of GSTA1 mRNA]

NCBI chr 9:23,703,476...23,720,121
Ensembl chr 9:23,703,477...23,720,121

G

glutathione S-transferase alpha 4

multiple interactions

[Acetylcysteine co-treated with EUK-134] promotes the reaction [[Zinc Sulfate co-treated with Paraquat] results in increased activity of GSTA4 protein]; [EUK-134 co-treated with Acetylcysteine] promotes the reaction [Paraquat results in increased activity of GSTA4 protein]; [EUK-134 co-treated with Acetylcysteine] promotes the reaction [Zinc Sulfate results in increased activity of GSTA4 protein]; Acetylcysteine inhibits the reaction [Fenitrothion results in decreased expression of GSTA4 mRNA]; Acetylcysteine promotes the reaction [[Paraquat co-treated with Maneb] results in increased expression of and results in increased activity of GSTA4 protein]; Acetylcysteine promotes the reaction [[Paraquat co-treated with Maneb] results in increased expression of GSTA4 mRNA]; Acetylcysteine promotes the reaction [Maneb results in increased expression of and results in increased activity of GSTA4 protein]; Acetylcysteine promotes the reaction [Maneb results in increased expression of GSTA4 mRNA]; Acetylcysteine promotes the reaction [Paraquat results in increased expression of and results in increased activity of GSTA4 protein]; Acetylcysteine promotes the reaction [Paraquat results in increased expression of GSTA4 mRNA]

PMID:23159886 PMID:25724285 PMID:30639957

NCBI chr 8:79,066,967...79,084,193
Ensembl chr 8:79,066,934...79,084,182

G

glutathione S-transferase alpha 5

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in increased expression of GSTA5 mRNA; Acetylcysteine inhibits the reaction [[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of GSTA5 mRNA]

NCBI chr 8:79,105,561...79,117,472
Ensembl chr 8:79,105,661...79,117,472

G

glutathione S-transferase mu 1

multiple interactions

Acetylcysteine inhibits the reaction [alpha-methylepinine results in increased expression of GSTM1 mRNA]
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in increased expression of GSTM1 mRNA

PMID:21871945 PMID:22129741

NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411

G

glutathione S-transferase mu 2

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in increased expression of GSTM2 mRNA

NCBI chr 2:195,624,015...195,628,774
Ensembl chr 2:195,544,426...195,628,961

G

glutathione S-transferase pi 1

multiple interactions

Acetylcysteine inhibits the reaction [[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of GSTP1 mRNA]

NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226

G

GULP PTB domain containing engulfment adaptor 1

decreases expression

Acetylcysteine results in decreased expression of GULP1 mRNA

NCBI chr 9:46,622,699...46,899,005
Ensembl chr 9:46,622,669...46,899,005

G

glycophorin A

multiple interactions

Acetylcysteine inhibits the reaction [Tetradecanoylphorbol Acetate results in decreased expression of GYPA protein]

NCBI chr19:27,450,304...27,465,940
Ensembl chr19:27,450,308...27,465,822

G

H2A.X variant histone

multiple interactions
increases expression

Acetylcysteine inhibits the reaction [2,3,5-(triglutathion-S-yl)hydroquinone results in increased phosphorylation of H2AX protein]; Acetylcysteine inhibits the reaction [2-hydroxy-3',5,5'-trimethoxychalcone results in increased phosphorylation of H2AX protein]; Acetylcysteine inhibits the reaction [4-biphenylamine results in increased expression of H2AX protein]; Acetylcysteine inhibits the reaction [4-methoxy-2,2,6,6-tetramethylpiperidinyl-1-oxy results in increased phosphorylation of H2AX protein]; Acetylcysteine inhibits the reaction [5-(3,4,5-trimethoxybenzoyl)-4-methyl-2-(p-tolyl)imidazole results in increased expression of H2AX protein]; Acetylcysteine inhibits the reaction [[Bortezomib co-treated with romidepsin] results in increased phosphorylation of H2AX protein]; Acetylcysteine inhibits the reaction [[fludarabine co-treated with LAQ824] results in increased expression of H2AX protein]; Acetylcysteine inhibits the reaction [Acetaminophen results in increased expression of H2AX protein]; Acetylcysteine inhibits the reaction [alpha-terthienylmethanol results in increased phosphorylation of H2AX protein]; Acetylcysteine inhibits the reaction [bisphenol A results in increased phosphorylation of H2AX protein]; Acetylcysteine inhibits the reaction [captax results in increased expression of H2AX protein]; Acetylcysteine inhibits the reaction [chloropicrin results in increased phosphorylation of H2AX protein]; Acetylcysteine inhibits the reaction [cobaltous chloride promotes the reaction [nickel chloride results in increased phosphorylation of H2AX protein]]; Acetylcysteine inhibits the reaction [cobaltous chloride results in increased phosphorylation of H2AX protein]; Acetylcysteine inhibits the reaction [Crizotinib results in increased phosphorylation of H2AX protein]; Acetylcysteine inhibits the reaction [dorsomorphin results in increased phosphorylation of H2AX protein]; Acetylcysteine inhibits the reaction [Doxorubicin results in increased phosphorylation of H2AX protein]; Acetylcysteine inhibits the reaction [eprenetapopt results in increased expression of H2AX protein modified form]; Acetylcysteine inhibits the reaction [gingerenone A results in increased expression of H2AX protein]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased expression of H2AX protein]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of H2AX protein]; Acetylcysteine inhibits the reaction [hydroquinone results in increased expression of H2AX protein]; Acetylcysteine inhibits the reaction [LAQ824 results in increased expression of H2AX protein]; Acetylcysteine inhibits the reaction [manumycin results in increased phosphorylation of H2AX protein]; Acetylcysteine inhibits the reaction [nickel chloride promotes the reaction [cobaltous chloride results in increased phosphorylation of H2AX protein]]; Acetylcysteine inhibits the reaction [nickel chloride results in increased phosphorylation of H2AX protein]; Acetylcysteine inhibits the reaction [PCB 180 metabolite results in increased phosphorylation of H2AX protein]; Acetylcysteine inhibits the reaction [phenanthridone results in increased expression of H2AX protein modified form]; Acetylcysteine inhibits the reaction [Plant Extracts results in increased expression of H2AX protein]; Acetylcysteine inhibits the reaction [polyhexamethyleneguanidine results in increased phosphorylation of H2AX protein]; Acetylcysteine inhibits the reaction [propylene dichloride results in increased phosphorylation of H2AX protein]; Acetylcysteine inhibits the reaction [scutebarbatine A results in increased expression of H2AX protein]; Acetylcysteine inhibits the reaction [tomentosin results in increased expression of H2AX protein]; Acetylcysteine inhibits the reaction [usnic acid results in increased expression of H2AX protein]
Acetylcysteine results in increased expression of H2AX protein
Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased phosphorylation of H2AX protein]; Acetylcysteine inhibits the reaction [aristolochic acid I results in increased expression of H2AX protein]; Acetylcysteine inhibits the reaction [tributyltin results in increased expression of H2AX protein modified form]; Acetylcysteine inhibits the reaction [yttrium chloride results in increased phosphorylation of H2AX protein]
Acetylcysteine inhibits the reaction [2,4-dibromophenol metabolite results in increased expression of H2AX protein modified form]; Acetylcysteine inhibits the reaction [diepoxybutane results in increased expression of H2AX protein modified form]; Acetylcysteine inhibits the reaction [quinone analog results in increased expression of H2AX protein modified form]; Acetylcysteine inhibits the reaction [Zinc Oxide analog results in increased activity of H2AX protein]

PMID:15173094 PMID:15489221 PMID:18852132 PMID:19409983 PMID:21135414 More...

NCBI chr 8:44,671,907...44,673,262
Ensembl chr 8:44,671,786...44,673,239

G

hyaluronan synthase 2

multiple interactions

Acetylcysteine inhibits the reaction [LHB protein results in increased abundance of HAS2 mRNA]

NCBI chr 7:88,113,326...88,139,337
Ensembl chr 7:88,113,326...88,128,933

G

hepatitis A virus cellular receptor 1

multiple interactions

Acetylcysteine inhibits the reaction [Acetaminophen results in increased expression of HAVCR1 protein]

NCBI chr10:31,118,667...31,151,730
Ensembl chr10:31,119,088...31,151,698

G

HCLS1 associated protein X-1

multiple interactions

Acetylcysteine inhibits the reaction [Tosylphenylalanyl Chloromethyl Ketone results in decreased expression of HAX1 protein]

NCBI chr 2:175,434,242...175,437,926
Ensembl chr 2:175,434,238...175,437,714

G

heparin-binding EGF-like growth factor

multiple interactions

Acetylcysteine inhibits the reaction [vanadium pentoxide results in increased expression of HBEGF mRNA]

NCBI chr18:28,106,284...28,116,167
Ensembl chr18:28,105,760...28,116,441

G

HECT domain E3 ubiquitin protein ligase 4

multiple interactions

Acetylcysteine inhibits the reaction [Ethanol results in increased expression of HECTD4 mRNA]; Acetylcysteine inhibits the reaction [sodium arsenite results in decreased expression of HECTD4 mRNA]

PMID:31004932 PMID:35713687

NCBI chr12:35,182,165...35,330,935
Ensembl chr12:35,182,154...35,330,987

G

homocysteine inducible ER protein with ubiquitin like domain 1

increases expression
multiple interactions

Acetylcysteine results in increased expression of HERPUD1 mRNA
Acetylcysteine inhibits the reaction [elesclomol results in increased expression of HERPUD1 mRNA]

PMID:16084531 PMID:18723479

NCBI chr19:10,598,411...10,609,002
Ensembl chr19:10,598,417...10,618,424

G

hepatocyte growth factor

multiple interactions

Acetylcysteine inhibits the reaction [TGFB1 protein results in increased expression of HGF protein]

NCBI chr 4:18,673,736...18,745,582
Ensembl chr 4:18,677,101...18,745,409

G

Hedgehog-interacting protein

multiple interactions

[Ethanol co-treated with Dietary Fats co-treated with Acetylcysteine] results in increased expression of HHIP mRNA

NCBI chr19:27,863,684...27,952,528
Ensembl chr19:27,863,213...27,952,528

G

hypoxia inducible factor 1 subunit alpha

multiple interactions

Acetylcysteine inhibits the reaction [Acetaminophen results in increased expression of HIF1A protein]; Acetylcysteine inhibits the reaction [chromium hexavalent ion results in increased expression of HIF1A protein]; Acetylcysteine inhibits the reaction [Polystyrenes analog results in increased expression of HIF1A protein]; Acetylcysteine inhibits the reaction [titanium dioxide results in increased expression of HIF1A protein]
Acetylcysteine inhibits the reaction [methylmercuric chloride results in decreased expression of HIF1A protein]; Acetylcysteine inhibits the reaction [Nickel analog results in increased expression of HIF1A protein]; Acetylcysteine inhibits the reaction [PDGFB protein promotes the reaction [Nickel analog results in increased expression of HIF1A protein]]
1-(2-chloroethyl)-1-nitrosourea inhibits the reaction [Acetylcysteine inhibits the reaction [Oxygen deficiency results in increased activity of HIF1A protein]]; Acetylcysteine inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of HIF1A protein]; Acetylcysteine inhibits the reaction [[Cadmium Chloride co-treated with sodium arsenite] results in increased expression of HIF1A mRNA]; Acetylcysteine inhibits the reaction [Antimycin A results in increased expression of HIF1A mRNA]; Acetylcysteine inhibits the reaction [Cadmium inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A protein]]; Acetylcysteine inhibits the reaction [Cadmium results in increased expression of HIF1A mRNA]; Acetylcysteine inhibits the reaction [Cisplatin affects the localization of HIF1A protein]; Acetylcysteine inhibits the reaction [cobaltous chloride results in increased expression of HIF1A protein]; Acetylcysteine inhibits the reaction [Dopamine results in increased expression of HIF1A protein]; Acetylcysteine inhibits the reaction [Fluorouracil affects the localization of HIF1A protein]; Acetylcysteine inhibits the reaction [nickel chloride results in increased expression of HIF1A protein]; Acetylcysteine inhibits the reaction [Oxygen deficiency results in increased activity of HIF1A protein]; Acetylcysteine inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A mRNA]; Acetylcysteine inhibits the reaction [sodium arsenite results in increased expression of HIF1A protein]; Acetylcysteine inhibits the reaction [titanium dioxide results in increased expression of HIF1A protein]; Acetylcysteine inhibits the reaction [Water Pollutants, Chemical results in increased expression of HIF1A mRNA]; ebselen inhibits the reaction [Acetylcysteine inhibits the reaction [Oxygen deficiency results in increased activity of HIF1A protein]]; ebselen inhibits the reaction [Acetylcysteine inhibits the reaction [Oxygen deficiency results in increased expression of HIF1A mRNA]]

PMID:10866824 PMID:11641398 PMID:11886167 PMID:13679210 PMID:16530163 More...

NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261

G

hexokinase 2

increases expression
multiple interactions

Acetylcysteine results in increased expression of HK2 mRNA
Acetylcysteine inhibits the reaction [NOX4 protein promotes the reaction [[Lipopolysaccharides co-treated with IFNG1 protein] results in increased expression of HK2 protein]]

PMID:16084531 PMID:36762617

NCBI chr 4:115,234,509...115,283,530
Ensembl chr 4:115,234,509...115,283,530

G

hydroxymethylbilane synthase

multiple interactions

Acetylcysteine inhibits the reaction [Aclarubicin results in increased expression of HMBS mRNA]; Acetylcysteine inhibits the reaction [Butyric Acid results in increased expression of HMBS mRNA]

NCBI chr 8:44,673,554...44,680,950
Ensembl chr 8:44,673,554...44,680,957

G

high mobility group AT-hook 2

multiple interactions

Acetylcysteine inhibits the reaction [Cadmium results in increased expression of HMGA2 protein]

NCBI chr 7:55,877,145...55,998,813
Ensembl chr 7:55,880,112...55,994,784

G

high mobility group box 1

multiple interactions

Acetylcysteine inhibits the reaction [2,3,5-trichloro-6-phenyl-(1,4)benzoquinone results in increased expression of HMGB1 protein]; Acetylcysteine inhibits the reaction [Acrolein promotes the reaction [Lipopolysaccharides results in increased expression of HMGB1 protein]]; Acetylcysteine inhibits the reaction [Acrolein results in increased expression of HMGB1 protein]; Acetylcysteine inhibits the reaction [Ethanol results in increased secretion of HMGB1 protein]

PMID:26079697 PMID:30977640 PMID:36055550

NCBI chr12:5,972,950...5,979,658
Ensembl chr12:5,901,586...5,978,565
Ensembl chr16:5,901,586...5,978,565

G

high mobility group box 2

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of HMGB2 mRNA

NCBI chr16:32,710,651...32,713,230
Ensembl chr16:32,710,658...32,713,140

G

3-hydroxy-3-methylglutaryl-CoA reductase

multiple interactions

Acetylcysteine inhibits the reaction [Benzo(a)pyrene results in decreased expression of HMGCR mRNA]

NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703

G

heme oxygenase 1

increases expression
multiple interactions
affects activity

Acetylcysteine results in increased expression of HMOX1 protein
Acetylcysteine inhibits the reaction [2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [2,2'-dihydroxychalcone results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [2-tert-butylhydroquinone results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [6-formylindolo(3,2-b)carbazole results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [[Arsenic Trioxide results in increased abundance of Peroxides] which results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [[Cadmium Chloride co-treated with Tetrachlorodibenzodioxin] results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [[chromium trioxide co-treated with Tetrachlorodibenzodioxin] results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [[Curcumin co-treated with piperine] results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [[monomethylarsonous acid results in increased abundance of Peroxides] which results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [[sodium arsenite co-treated with Tetrachlorodibenzodioxin] results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [Acetaminophen results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [Buthionine Sulfoximine results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [Cadmium results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [cadmium sulfate results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [carnosol results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [chromium hexavalent ion results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [chromium trioxide results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [cobaltiprotoporphyrin results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [Copper Sulfate results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [Diclofenac results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [Dimethyl Fumarate results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [Drugs, Chinese Herbal results in increased expression of HMOX1]; Acetylcysteine inhibits the reaction [Hemin results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [hydroquinone results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in decreased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [Melatonin inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of HMOX1 mRNA]]; Acetylcysteine inhibits the reaction [Melatonin inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of HMOX1 protein]]; Acetylcysteine inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [oxidized-L-alpha-1-palmitoyl-2-arachidonoyl-sn-glycero-3-phosphorylcholine results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [Quercetin analog results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [sodium arsenite results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [Tobacco Smoke Pollution analog results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [Tobacco Smoke Pollution results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [Urea results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [Vehicle Emissions analog results in increased expression of HMOX1 protein]; Polymyxin B inhibits the reaction [Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of HMOX1 mRNA]]
[Acetylcysteine results in increased abundance of Glutathione] inhibits the reaction [sodium arsenite results in increased expression of HMOX1 mRNA]; Acetylcysteine affects the reaction [Chlorpyrifos affects the expression of HMOX1 protein]; Acetylcysteine affects the reaction [Pyruvaldehyde affects the expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [2-butenal results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [2-xylene results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [3-O-caffeoyl-1-methylquinic acid results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [4-(methylthio)-3-butenyl isothiocyanate results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [4-(methylthio)-3-butenyl isothiocyanate results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [[[[15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of and results in increased activity of HMOX1 protein] which results in increased abundance of Iron] which results in increased abundance of Reactive Oxygen Species] which results in increased expression of MMP1 protein]; Acetylcysteine inhibits the reaction [[sodium arsenite results in increased abundance of arsenite] which results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [[tin protoporphyrin IX results in decreased activity of HMOX1 protein] which results in increased chemical synthesis of Reactive Oxygen Species]; Acetylcysteine inhibits the reaction [[TYMP protein co-treated with Thymidine] results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] which results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] which results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [Ammonium Chloride results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [Benzene results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [bisphenol A results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [cadmium acetate results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [Cadmium results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [camphorquinone results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [Cannabidiol results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [Capsaicin results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [chloropicrin results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [Curcumin results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [diallyl trisulfide results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [Dinitrochlorobenzene results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [Docosahexaenoic Acids promotes the reaction [NFE2L2 protein binds to HMOX1 enhancer]]; Acetylcysteine inhibits the reaction [Docosahexaenoic Acids results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [elesclomol results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [Ethacrynic Acid results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [Ethacrynic Acid results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [Fenretinide results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [gallium nitrate results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [Hypochlorous Acid results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [lead acetate results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [Mercury results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [nickel chloride promotes the reaction [lipopolysaccharide A results in increased expression of HMOX1 protein]]; Acetylcysteine inhibits the reaction [nickel chloride results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [Particulate Matter analog results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [phenethyl isothiocyanate results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [phenethyl isothiocyanate results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [Polychlorinated Biphenyls analog results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [Polystyrenes analog results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [Potassium Dichromate results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [Ritonavir results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [Ritonavir results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [Silicon analog results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [Silver analog results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [sodium arsenite promotes the reaction [NFE2L2 protein binds to HMOX1 enhancer]]; Acetylcysteine inhibits the reaction [sodium arsenite results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [sodium arsenite results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [sulforaphane results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [tetrabromobisphenol A results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [tetrathiomolybdate analog results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [thymoquinone results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [Tobacco Smoke Pollution analog results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [Toluene results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [Vehicle Emissions analog results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [Vehicle Emissions results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [Zinc results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [Zinc results in increased expression of HMOX1 protein]; Acetylcysteine promotes the reaction [Arsenic Trioxide results in increased expression of HMOX1 protein]; Acetylcysteine promotes the reaction [Omeprazole results in increased expression of HMOX1 mRNA]; Acetylcysteine promotes the reaction [Omeprazole results in increased expression of HMOX1 protein]; Acetylcysteine promotes the reaction [Oxygen results in increased expression of HMOX1 mRNA]
[Acetylcysteine affects the abundance of Reactive Oxygen Species] inhibits the reaction [manganese chloride promotes the reaction [NFE2L2 protein binds to HMOX1 promoter]]; [Acetylcysteine affects the abundance of Reactive Oxygen Species] inhibits the reaction [manganese chloride results in increased expression of HMOX1 protein]; Acetylcysteine affects the reaction [Glucose affects the expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [4-hydroxy-2-nonenal results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [4-hydroxy-2-nonenal results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [arsenite results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [aureusidin results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [Cadmium results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [Chlorpyrifos results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [cypermethrin results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [decamethrin results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [decamethrin results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [Diclofenac results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in decreased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [methylmercuric chloride results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [Oxidopamine results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [oxophenylarsine results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [Particulate Matter analog results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [Particulate Matter analog results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [sodium arsenite results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [Sodium Fluoride results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [Sodium Fluoride results in increased expression of HMOX1 protein]; Acetylcysteine inhibits the reaction [Vehicle Emissions analog results in increased expression of HMOX1 mRNA]; Acetylcysteine inhibits the reaction [Vehicle Emissions analog results in increased expression of HMOX1 protein]
Acetylcysteine affects the activity of HMOX1 protein
Acetylcysteine results in increased expression of HMOX1 mRNA; Acetylcysteine results in increased expression of HMOX1 protein

PMID:7538129 PMID:9152014 PMID:9545559 PMID:9747510 PMID:10975858 More...

NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079

G

hepatocyte nuclear factor 4, gamma

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of HNF4G mRNA

NCBI chr 2:97,885,773...98,036,650
Ensembl chr 2:97,887,432...98,036,592

G

HRas proto-oncogene, GTPase

multiple interactions

Acetylcysteine inhibits the reaction [Nitrofurazone results in increased expression of HRAS mRNA]
Acetylcysteine inhibits the reaction [HRAS protein mutant form results in increased susceptibility to sodium arsenite]

PMID:15945272 PMID:25199681

NCBI chr 1:196,290,127...196,299,823
Ensembl chr 1:196,296,263...196,300,615

G

heat shock factor binding protein 1

multiple interactions

Acetylcysteine inhibits the reaction [Thioacetamide results in increased expression of HSBP1 protein]

NCBI chr19:47,401,039...47,405,373
Ensembl chr19:47,400,966...47,435,821

G

hydroxysteroid 11-beta dehydrogenase 2

multiple interactions

Acetylcysteine inhibits the reaction [SOD2 protein affects the expression of HSD11B2 mRNA]

NCBI chr19:33,397,656...33,402,899
Ensembl chr19:33,397,656...33,402,899

G

hydroxysteroid (17-beta) dehydrogenase 3

multiple interactions

Acetylcysteine inhibits the reaction [Dimethoate results in decreased expression of HSD17B3 mRNA]; Acetylcysteine inhibits the reaction [nickel sulfate results in decreased expression of HSD17B3 mRNA]

PMID:26769589 PMID:29567110

NCBI chr17:1,027,229...1,058,554
Ensembl chr17:1,027,229...1,058,554

G

hydroxysteroid (17-beta) dehydrogenase 8

multiple interactions

Acetylcysteine inhibits the reaction [SOD2 protein affects the expression of HSD17B8 mRNA]

NCBI chr20:4,826,725...4,828,742
Ensembl chr20:4,822,026...4,828,742

G

hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 3

multiple interactions

Acetylcysteine inhibits the reaction [Dimethoate results in decreased expression of HSD3B3 mRNA]

NCBI chr 2:186,138,044...186,144,024
Ensembl chr 2:186,138,044...186,144,033

G

heat shock transcription factor 1

multiple interactions

Acetylcysteine inhibits the reaction [Cadmium Chloride results in decreased activity of HSF1 protein]; Acetylcysteine inhibits the reaction [Particulate Matter affects the localization of HSF1 protein]; Acetylcysteine inhibits the reaction [sodium arsenite promotes the reaction [NFE2L2 protein binds to HSF1 promoter]]; Acetylcysteine inhibits the reaction [Vehicle Emissions affects the localization of HSF1 protein]

PMID:10403520 PMID:17922515 PMID:30309986

NCBI chr 7:108,196,040...108,223,011
Ensembl chr 7:108,196,056...108,223,011

G

heat shock protein 90 beta family member 1

multiple interactions

Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of HSP90B1 mRNA]; Acetylcysteine inhibits the reaction [chloroacetic acid results in increased expression of HSP90B1 protein]; Acetylcysteine inhibits the reaction [methylmercuric chloride results in increased expression of HSP90B1 protein]; Acetylcysteine inhibits the reaction [sodium arsenite results in increased expression of HSP90B1 protein]
Acetylcysteine inhibits the reaction [2,3,5-trichloro-6-phenyl-(1,4)benzoquinone results in increased expression of HSP90B1 protein]
Acetylcysteine inhibits the reaction [arsenic trioxide results in increased expression of HSP90B1 protein]

PMID:21145380 PMID:21533816 PMID:21911445 PMID:25451595 PMID:25950987 More...

NCBI chr 7:21,110,431...21,124,762
Ensembl chr 7:21,110,457...21,124,788

G

heat shock protein family A (Hsp70) member 1A

multiple interactions

Acetylcysteine inhibits the reaction [elesclomol results in increased expression of HSPA1A mRNA]; Acetylcysteine inhibits the reaction [Hypochlorous Acid results in increased expression of HSPA1A protein]; Acetylcysteine inhibits the reaction [Mercuric Chloride results in increased expression of HSPA1A mRNA]
Acetylcysteine inhibits the reaction [methylmercuric chloride results in increased expression of HSPA1A protein]

PMID:12231548 PMID:16324719 PMID:18723479 PMID:36813253

NCBI chr20:3,870,765...3,873,221
Ensembl chr20:3,856,006...3,873,227

G

heat shock protein family A (Hsp70) member 1B

multiple interactions

Acetylcysteine inhibits the reaction [elesclomol results in increased expression of HSPA1B mRNA]
Acetylcysteine inhibits the reaction [arsenite results in increased expression of HSPA1B protein]

PMID:15175009 PMID:18723479

NCBI chr20:3,855,104...3,859,148
Ensembl chr20:3,856,006...3,873,240
Ensembl chr20:3,856,006...3,873,240

G

heat shock protein family A (Hsp70) member 5

increases expression
multiple interactions
decreases expression

Acetylcysteine results in increased expression of HSPA5 protein
Acetylcysteine inhibits the reaction [4-hydroxy-2-nonenal results in increased expression of HSPA5 mRNA]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of HSPA5 protein]; Acetylcysteine inhibits the reaction [gadolinium chloride results in increased expression of HSPA5 protein]; Acetylcysteine inhibits the reaction [nickel sulfate results in increased expression of HSPA5 mRNA]; Acetylcysteine inhibits the reaction [nickel sulfate results in increased expression of HSPA5 protein]; Acetylcysteine inhibits the reaction [Sodium Fluoride results in increased expression of HSPA5 protein]; Acetylcysteine inhibits the reaction [tetrachlorobenzoquinone results in increased expression of HSPA5 protein]
Acetylcysteine results in decreased expression of HSPA5 protein
4-phenylbutyric acid promotes the reaction [Acetylcysteine inhibits the reaction [tris(1,3-dichloro-2-propyl)phosphate results in increased expression of HSPA5 protein]]; Acetylcysteine inhibits the reaction [(1-pentyl-1H-indol-3-yl)(2,2,3,3-tetramethylcyclopropyl)methanone results in increased expression of HSPA5 mRNA]; Acetylcysteine inhibits the reaction [(4-methyl-1-naphthyl)-(1-pentylindol-3-yl)methanone results in increased expression of HSPA5 mRNA]; Acetylcysteine inhibits the reaction [2,3,5-trichloro-6-phenyl-(1,4)benzoquinone results in increased expression of HSPA5 protein]; Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of HSPA5 protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide promotes the reaction [Resveratrol results in increased expression of HSPA5 protein]]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of HSPA5 protein]; Acetylcysteine inhibits the reaction [Benomyl results in increased expression of HSPA5 protein]; Acetylcysteine inhibits the reaction [discretamine results in increased expression of HSPA5 protein]; Acetylcysteine inhibits the reaction [Ethylmercury Compounds affects the expression of HSPA5 mRNA]; Acetylcysteine inhibits the reaction [fangchinoline results in increased expression of HSPA5 protein]; Acetylcysteine inhibits the reaction [hesperetin results in increased expression of HSPA5 protein]; Acetylcysteine inhibits the reaction [hydroquinone results in increased expression of HSPA5 protein]; Acetylcysteine inhibits the reaction [plumbagin results in increased expression of HSPA5 protein]; Acetylcysteine inhibits the reaction [pterostilbene results in increased expression of HSPA5 protein]; Acetylcysteine inhibits the reaction [Resveratrol promotes the reaction [Arsenic Trioxide results in increased expression of HSPA5 protein]]; Acetylcysteine inhibits the reaction [Resveratrol results in increased expression of HSPA5 protein]; Acetylcysteine inhibits the reaction [sodium arsenite results in increased expression of HSPA5 protein]; Acetylcysteine inhibits the reaction [tris(1,3-dichloro-2-propyl)phosphate results in increased expression of HSPA5 protein]; Acetylcysteine inhibits the reaction [Ursolic Acid results in increased expression of HSPA5 protein]; Acetylcysteine promotes the reaction [4-phenylbutyric acid inhibits the reaction [tris(1,3-dichloro-2-propyl)phosphate results in increased expression of HSPA5 protein]]
Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of HSPA5 mRNA]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of HSPA5 protein]; Acetylcysteine inhibits the reaction [Brefeldin A results in increased expression of HSPA5 protein]; Acetylcysteine inhibits the reaction [chloroacetic acid results in increased expression of HSPA5 protein]; Acetylcysteine inhibits the reaction [methylmercuric chloride results in increased expression of HSPA5 protein]; Acetylcysteine inhibits the reaction [sodium arsenite results in increased expression of HSPA5 protein]; Acetylcysteine inhibits the reaction [Thapsigargin results in increased expression of HSPA5 protein]

PMID:19722195 PMID:20493918 PMID:21145380 PMID:21198628 PMID:21533816 More...

NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891

G

heat shock protein family B (small) member 1

multiple interactions

Acetylcysteine inhibits the reaction [arsenite results in increased expression of HSPB1 protein]

NCBI chr12:20,794,014...20,795,675
Ensembl chr12:20,794,028...20,795,743

G

heat shock protein family D (Hsp60) member 1

multiple interactions

Acetylcysteine inhibits the reaction [[EGF co-treated with Colforsin co-treated with Rotenone] results in increased expression of HSPD1 mRNA]; Acetylcysteine inhibits the reaction [Chlorine results in increased expression of HSPD1 protein]; Acetylcysteine inhibits the reaction [Rotenone results in increased expression of HSPD1 mRNA]

PMID:32092105 PMID:35065218

NCBI chr 9:56,579,195...56,590,011
Ensembl chr 9:56,579,201...56,589,662

G

HIV-1 Tat interactive protein 2

decreases expression

Acetylcysteine results in decreased expression of HTATIP2 mRNA

NCBI chr 1:99,473,411...99,488,632
Ensembl chr 1:99,469,245...99,488,629

G

intercellular adhesion molecule 1

affects expression
multiple interactions
decreases expression

Acetylcysteine affects the expression of ICAM1
Acetylcysteine affects the reaction [Dinitrochlorobenzene affects the expression of ICAM1 protein]; Acetylcysteine inhibits the reaction [2,3,5-trichloro-6-phenyl-(1,4)benzoquinone results in increased expression of ICAM1 protein]; Acetylcysteine inhibits the reaction [Dimethyl Fumarate inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA]]; Acetylcysteine inhibits the reaction [Norepinephrine results in increased expression of ICAM1 mRNA]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of ICAM1 mRNA]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of ICAM1 protein]; Acetylcysteine inhibits the reaction [Sodium Fluoride results in increased expression of ICAM1 protein]; Acetylcysteine inhibits the reaction [tetrachlorobenzoquinone results in increased expression of ICAM1 protein]; Acetylcysteine inhibits the reaction [Tin Fluorides results in increased expression of ICAM1 protein]; Acetylcysteine inhibits the reaction [TNF protein results in increased expression of ICAM1 protein]; Acetylcysteine inhibits the reaction [Vehicle Emissions results in increased expression of ICAM1 mRNA]; Acetylcysteine inhibits the reaction [Vehicle Emissions results in increased expression of ICAM1 protein]
Acetylcysteine inhibits the reaction [Lipopolysaccharides results in increased expression of ICAM1 mRNA]; Acetylcysteine inhibits the reaction [Methotrexate results in increased expression of ICAM1 mRNA]
Acetylcysteine results in decreased expression of ICAM1 mRNA
Acetylcysteine inhibits the reaction [Drugs, Chinese Herbal inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of ICAM1 protein]]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of and results in increased secretion of ICAM1 protein]; Acetylcysteine inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA]

PMID:10495789 PMID:10792388 PMID:11736926 PMID:17416599 PMID:17666914 More...

NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438

G

inhibitor of DNA binding 2

decreases expression

Acetylcysteine results in decreased expression of ID2 mRNA

NCBI chr 6:41,740,556...41,742,393
Ensembl chr 6:41,728,946...41,744,400

G

isocitrate dehydrogenase (NADP(+)) 2

multiple interactions

Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in decreased activity of IDH2 protein]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in decreased expression of IDH2 protein]

NCBI chr 1:134,038,644...134,057,969
Ensembl chr 1:134,029,772...134,058,025

G

immediate early response 3

multiple interactions
affects response to substance

Acetylcysteine affects the reaction [IER3 protein affects the expression of GNAI2 mRNA]
IER3 protein affects the susceptibility to Acetylcysteine

NCBI chr20:2,928,378...2,929,582
Ensembl chr20:2,928,378...2,929,583

G

immediate early response 5

multiple interactions

Acetylcysteine inhibits the reaction [elesclomol results in increased expression of IER5 mRNA]

NCBI chr13:67,270,134...67,272,226
Ensembl chr13:67,270,135...67,272,227

G

interferon-induced protein with tetratricopeptide repeats 2

multiple interactions

Acetylcysteine inhibits the reaction [Dieldrin inhibits the reaction [Poly I-C results in increased expression of IFIT2 mRNA]]

NCBI chr 1:232,102,570...232,108,638
Ensembl chr 1:232,102,570...232,108,635

G

interferon gamma

multiple interactions

Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of IFNG protein]; Acetylcysteine inhibits the reaction [Eosine I Bluish results in increased expression of IFNG mRNA]; Acetylcysteine inhibits the reaction [Formaldehyde results in decreased expression of IFNG mRNA]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased secretion of IFNG protein]
Acetylcysteine inhibits the reaction [Malathion results in increased expression of IFNG mRNA]
Acetylcysteine inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IFNG protein results in increased phosphorylation of and results in increased activity of JAK2 protein]]; Acetylcysteine inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IFNG protein results in increased phosphorylation of STAT1 protein]]; Acetylcysteine inhibits the reaction [Azoxymethane results in increased expression of IFNG protein]; Acetylcysteine inhibits the reaction [Lipopolysaccharides results in increased expression of IFNG protein]; Acetylcysteine promotes the reaction [IFNG protein results in increased phosphorylation of and results in increased activity of JAK2 protein]; Acetylcysteine promotes the reaction [IFNG protein results in increased phosphorylation of STAT1 protein]

PMID:12847270 PMID:15004186 PMID:18849615 PMID:20431929 PMID:22440610 More...

NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375

G

interferon-related developmental regulator 1

multiple interactions

Acetylcysteine inhibits the reaction [elesclomol results in increased expression of IFRD1 mRNA]

NCBI chr 6:57,269,395...57,317,833
Ensembl chr 6:57,269,384...57,288,990

G

insulin-like growth factor 1

multiple interactions

Acetylcysteine inhibits the reaction [[IGF1 protein co-treated with Estradiol] results in increased expression of JUN protein]; Acetylcysteine inhibits the reaction [[IGF1 protein co-treated with Estradiol] results in increased phosphorylation of IRS1 protein]; Acetylcysteine inhibits the reaction [[IGF1 protein co-treated with Estradiol] results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [[IGF1 protein co-treated with Estradiol] results in increased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of IGF1 protein]

PMID:17458902 PMID:26138014

NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296

G

insulin-like growth factor 1 receptor

multiple interactions

Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of IGF1R protein]

NCBI chr 1:121,549,831...121,838,548
Ensembl chr 1:121,550,743...121,831,777

G

insulin-like growth factor binding protein 1

multiple interactions

Acetylcysteine inhibits the reaction [[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of IGFBP1 mRNA]
Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of IGFBP1 protein]

PMID:22129741 PMID:26138014

NCBI chr14:82,047,415...82,052,482
Ensembl chr14:82,047,415...82,052,482

G

insulin-like growth factor binding protein 2

multiple interactions

Acetylcysteine inhibits the reaction [Cadmium Chloride results in decreased expression of IGFBP2 protein]

NCBI chr 9:74,415,574...74,442,945
Ensembl chr 9:74,415,546...74,442,937

G

insulin-like growth factor binding protein 4

multiple interactions

Acetylcysteine inhibits the reaction [Cadmium Chloride results in decreased secretion of IGFBP4 protein]

NCBI chr10:83,995,253...84,007,272
Ensembl chr10:83,989,591...84,007,225

G

inhibitor of nuclear factor kappa B kinase subunit beta

decreases activity
multiple interactions

Acetylcysteine results in decreased activity of IKBKB protein
Acetylcysteine inhibits the reaction [Acetaminophen results in increased expression of IKBKB mRNA]
Acetylcysteine inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased phosphorylation of IKBKB protein]

PMID:17395010 PMID:34310962 PMID:37458150

NCBI chr16:69,319,487...69,373,251
Ensembl chr16:69,319,554...69,373,250

G

interleukin 10

multiple interactions

[Eugenol co-treated with Acetylcysteine] inhibits the reaction [Nicotine results in decreased secretion of IL10 protein]; Acetylcysteine inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of IL10 protein]; Acetylcysteine inhibits the reaction [Azoxymethane results in increased expression of IL10 protein]; Acetylcysteine inhibits the reaction [Nicotine results in decreased expression of IL10 mRNA]
Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of IL10 protein]; Acetylcysteine inhibits the reaction [Lipopolysaccharides results in increased expression of IL10 mRNA]; Acetylcysteine inhibits the reaction [Lipopolysaccharides results in increased expression of IL10 protein]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased secretion of IL10 protein]
Acetylcysteine inhibits the reaction [Methotrexate results in decreased secretion of IL10 protein]; Acetylcysteine promotes the reaction [Doxorubicin results in increased expression of IL10 mRNA]

PMID:11124598 PMID:20431929 PMID:20885979 PMID:21237301 PMID:21424515 More...

NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313

G

interleukin 10 receptor subunit beta

decreases expression

Acetylcysteine results in decreased expression of IL10RB mRNA

NCBI chr11:30,646,494...30,668,081
Ensembl chr11:30,652,096...30,668,074

G

interleukin 12A

multiple interactions

Acetylcysteine inhibits the reaction [Nicotine results in increased secretion of [IL12A protein co-treated with IL12B protein]]

NCBI chr 2:152,965,769...152,973,035
Ensembl chr 2:152,965,769...152,972,734

G

interleukin 12B

multiple interactions

Acetylcysteine inhibits the reaction [Nicotine results in increased expression of IL12B mRNA]; Acetylcysteine inhibits the reaction [Nicotine results in increased secretion of [IL12A protein co-treated with IL12B protein]]

NCBI chr10:28,888,832...28,903,802
Ensembl chr10:28,893,008...28,902,903

G

interleukin 13

multiple interactions

Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of and results in increased secretion of IL13 protein]

NCBI chr10:37,790,130...37,792,687
Ensembl chr10:37,790,130...37,792,737

G

interleukin 15

multiple interactions

Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of IL15 protein]

NCBI chr19:25,640,025...25,706,818
Ensembl chr19:25,640,251...25,706,820

G

interleukin 16

multiple interactions

Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of IL16 protein]

NCBI chr 1:137,617,702...137,718,022
Ensembl chr 1:137,617,944...137,718,130

G

interleukin 17A

multiple interactions

Acetylcysteine inhibits the reaction [Azoxymethane results in increased expression of IL17A protein]; Acetylcysteine inhibits the reaction [Trichloroethylene results in increased expression of IL17A mRNA]

PMID:20431929 PMID:23993974

NCBI chr 9:23,144,402...23,147,889
Ensembl chr 9:23,144,402...23,147,889

G

interleukin 17D

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of IL17D mRNA

NCBI chr15:31,671,337...31,688,833

G

interleukin 18

multiple interactions

Acetylcysteine inhibits the reaction [Adenosine Triphosphate results in increased secretion of IL18 protein]; Acetylcysteine inhibits the reaction [Benzo(a)pyrene results in increased secretion of IL18 protein]; Acetylcysteine inhibits the reaction [Silicon Dioxide analog results in increased secretion of IL18 protein]
Acetylcysteine inhibits the reaction [Acetaminophen results in increased expression of IL18 protein]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of IL18 protein]
Acetylcysteine inhibits the reaction [[Acrolein co-treated with Lipopolysaccharides] results in increased expression of IL18 protein]; Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of IL18 mRNA]; Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of IL18 protein]; Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased secretion of IL18 protein]; Acetylcysteine inhibits the reaction [Acrolein promotes the reaction [Lipopolysaccharides results in increased expression of IL18 protein]]; Acetylcysteine inhibits the reaction [Acrolein results in increased expression of IL18 protein]; Acetylcysteine inhibits the reaction [hydroquinone results in increased secretion of IL18 protein]; Acetylcysteine inhibits the reaction [Lipopolysaccharides promotes the reaction [Acrolein results in increased expression of IL18 protein]]; Acetylcysteine inhibits the reaction [Lipopolysaccharides results in increased secretion of IL18 protein]; Acetylcysteine inhibits the reaction [saikosaponin D results in increased secretion of IL18 protein]; Quercetin promotes the reaction [Acetylcysteine inhibits the reaction [Lipopolysaccharides results in increased secretion of IL18 protein]]

PMID:27311643 PMID:30205151 PMID:34510229 PMID:34791735 PMID:35020164 More...

NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887

G

interleukin 1 alpha

multiple interactions

[Acetylcysteine co-treated with IL1A protein] results in increased expression of SOD2 protein; Acetylcysteine inhibits the reaction [butylphen results in increased expression of IL1A protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of IL1A protein]; Acetylcysteine inhibits the reaction [hydroquinone results in increased expression of IL1A protein]; Acetylcysteine inhibits the reaction [sodium arsenite results in increased expression of IL1A mRNA]; Acetylcysteine promotes the reaction [IL1A protein results in increased expression of SOD2 mRNA]; Acetylcysteine promotes the reaction [PIK3R1 protein modified form inhibits the reaction [butylphen results in increased expression of IL1A protein]]; Acetylcysteine promotes the reaction [PIK3R1 protein modified form inhibits the reaction [hydroquinone results in increased expression of IL1A protein]]

PMID:7476933 PMID:24570342 PMID:26138014 PMID:28836394

NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822

G

interleukin 1 beta

multiple interactions
increases expression
decreases expression
affects expression

Acetylcysteine analog inhibits the reaction [2-chloroethyl ethyl sulfide results in increased expression of IL1B protein]; Acetylcysteine analog inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B protein]; Acetylcysteine inhibits the reaction [[Buthionine Sulfoximine co-treated with Lipopolysaccharides] results in increased secretion of IL1B protein]; Acetylcysteine inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of IL1B mRNA]; Acetylcysteine inhibits the reaction [Acrylonitrile results in increased expression of IL1B mRNA]; Acetylcysteine inhibits the reaction [Buthionine Sulfoximine results in increased secretion of IL1B protein]; Acetylcysteine inhibits the reaction [cadmium acetate results in increased cleavage of IL1B protein]; Acetylcysteine inhibits the reaction [cadmium acetate results in increased secretion of IL1B protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of IL1B mRNA]; Acetylcysteine inhibits the reaction [cypermethrin results in increased expression of IL1B protein]; Acetylcysteine inhibits the reaction [Fenitrothion results in increased expression of IL1B protein]; Acetylcysteine inhibits the reaction [IL1B protein results in increased expression of CCL2 mRNA]; Acetylcysteine inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1B protein]; Acetylcysteine inhibits the reaction [Malathion results in increased expression of IL1B mRNA]; Acetylcysteine inhibits the reaction [Paraquat results in increased expression of IL1B mRNA]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of IL1B protein]
Acetylcysteine results in increased expression of IL1B protein
[Acetylcysteine co-treated with Cobalt] results in decreased expression of IL1B protein; Acetylcysteine inhibits the reaction [2,3,5-trichloro-6-phenyl-(1,4)benzoquinone results in increased expression of IL1B protein modified form]; Acetylcysteine inhibits the reaction [2,3,5-trichloro-6-phenyl-(1,4)benzoquinone results in increased expression of IL1B protein]; Acetylcysteine inhibits the reaction [2,4-decadienal results in increased expression of and results in increased secretion of IL1B protein]; Acetylcysteine inhibits the reaction [[Acrolein co-treated with Lipopolysaccharides] results in increased expression of IL1B protein]; Acetylcysteine inhibits the reaction [[Antimycin A co-treated with IL1B protein] results in increased expression of CXCL8 protein]; Acetylcysteine inhibits the reaction [[Cadmium Chloride co-treated with Lipopolysaccharides] results in increased cleavage of IL1B protein]; Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of IL1B mRNA]; Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of IL1B protein]; Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased secretion of IL1B protein]; Acetylcysteine inhibits the reaction [[IL1B protein co-treated with Oligomycins] results in increased expression of PTGS2 protein]; Acetylcysteine inhibits the reaction [[Oligomycins co-treated with IL1B protein] results in increased expression of CXCL8 protein]; Acetylcysteine inhibits the reaction [[Peanut Oil results in increased abundance of Particulate Matter] which results in increased expression of IL1B mRNA]; Acetylcysteine inhibits the reaction [[Peanut Oil results in increased abundance of Particulate Matter] which results in increased expression of IL1B protein]; Acetylcysteine inhibits the reaction [Acetaminophen results in increased expression of IL1B mRNA]; Acetylcysteine inhibits the reaction [Acrolein promotes the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]]; Acetylcysteine inhibits the reaction [Acrolein promotes the reaction [Lipopolysaccharides results in increased expression of IL1B protein]]; Acetylcysteine inhibits the reaction [Acrolein results in increased expression of IL1B mRNA]; Acetylcysteine inhibits the reaction [Acrolein results in increased expression of IL1B protein]; Acetylcysteine inhibits the reaction [APP protein results in increased expression of and results in increased cleavage of IL1B protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased secretion of IL1B protein]; Acetylcysteine inhibits the reaction [Chlorpyrifos results in increased secretion of IL1B protein]; Acetylcysteine inhibits the reaction [Cobalt results in increased expression of IL1B protein modified form]; Acetylcysteine inhibits the reaction [cobaltous chloride results in increased secretion of IL1B protein]; Acetylcysteine inhibits the reaction [hydroquinone results in increased expression of and results in increased secretion of IL1B protein]; Acetylcysteine inhibits the reaction [IL1B promotes the reaction [EP300 protein binds to RELA protein]]; Acetylcysteine inhibits the reaction [IL1B protein results in increased abundance of Reactive Oxygen Species]; Acetylcysteine inhibits the reaction [IL1B protein results in increased expression of CXCL8 mRNA]; Acetylcysteine inhibits the reaction [IL1B protein results in increased expression of RELA protein modified form]; Acetylcysteine inhibits the reaction [IL1B protein results in increased expression of VCAM1 mRNA]; Acetylcysteine inhibits the reaction [IL1B protein results in increased expression of VCAM1 protein]; Acetylcysteine inhibits the reaction [Imatinib Mesylate results in increased secretion of IL1B protein]; Acetylcysteine inhibits the reaction [Lipopolysaccharides promotes the reaction [Acrolein results in increased expression of IL1B mRNA]]; Acetylcysteine inhibits the reaction [Lipopolysaccharides promotes the reaction [Acrolein results in increased expression of IL1B protein]]; Acetylcysteine inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]; Acetylcysteine inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1B protein]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of IL1B mRNA]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of IL1B protein]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased secretion of IL1B protein]; Acetylcysteine inhibits the reaction [saikosaponin D results in increased secretion of IL1B protein]; Acetylcysteine inhibits the reaction [sodium arsenite results in increased expression of IL1B mRNA]; Acetylcysteine inhibits the reaction [tetrachlorobenzoquinone results in increased expression of IL1B protein]; Acetylcysteine inhibits the reaction [tetrachlorobenzoquinone results in increased secretion of IL1B protein modified form]; Acetylcysteine inhibits the reaction [TNF protein results in increased secretion of IL1B protein]; Acetylcysteine inhibits the reaction [Uric Acid results in increased secretion of IL1B protein]; Acetylcysteine inhibits the reaction [Vehicle Emissions results in increased expression of IL1B protein]; Acetylcysteine inhibits the reaction [xanthohumol results in increased expression of IL1B protein]; Acetylcysteine promotes the reaction [Particulate Matter results in increased expression of IL1B mRNA]; Acetylcysteine promotes the reaction [titanium dioxide results in increased secretion of IL1B protein]; Quercetin promotes the reaction [Acetylcysteine inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1B protein]]
[Acetylcysteine results in decreased abundance of Reactive Oxygen Species] inhibits the reaction [Lipopolysaccharides promotes the reaction [Polystyrenes results in increased expression of IL1B mRNA]]; [Acetylcysteine results in decreased abundance of Reactive Oxygen Species] inhibits the reaction [Lipopolysaccharides promotes the reaction [Polystyrenes results in increased expression of IL1B protein]]; [Acetylcysteine results in decreased abundance of Reactive Oxygen Species] inhibits the reaction [Polystyrenes promotes the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA]]; [Acetylcysteine results in decreased abundance of Reactive Oxygen Species] inhibits the reaction [Polystyrenes promotes the reaction [Lipopolysaccharides results in increased expression of IL1B protein]]; Acetylcysteine inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of IL1B mRNA]; Acetylcysteine inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of IL1B protein]; Acetylcysteine inhibits the reaction [[Potassium Dichromate results in increased abundance of chromium hexavalent ion] which results in increased expression of IL1B protein]; Acetylcysteine inhibits the reaction [Acetaminophen results in increased expression of IL1B protein]; Acetylcysteine inhibits the reaction [Adenosine Triphosphate results in increased secretion of IL1B protein]; Acetylcysteine inhibits the reaction [Aluminum Chloride results in increased expression of IL1B mRNA]; Acetylcysteine inhibits the reaction [Aluminum Chloride results in increased expression of IL1B protein]; Acetylcysteine inhibits the reaction [Asbestos, Crocidolite results in increased secretion of IL1B protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of IL1B mRNA]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of IL1B protein]; Acetylcysteine inhibits the reaction [Glucose results in increased expression of IL1B protein]; Acetylcysteine inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased secretion of IL1B protein]; Acetylcysteine inhibits the reaction [Lipopolysaccharides results in increased secretion of IL1B protein]; Acetylcysteine inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of IL1B protein]; Acetylcysteine inhibits the reaction [NOX4 protein promotes the reaction [[Lipopolysaccharides co-treated with IFNG1 protein] results in increased expression of IL1B protein]]; Acetylcysteine inhibits the reaction [Paraquat results in increased expression of IL1B mRNA]; Acetylcysteine inhibits the reaction [Paraquat results in increased secretion of IL1B protein]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased secretion of IL1B protein]; Acetylcysteine inhibits the reaction [Rotenone results in increased expression of and results in increased secretion of IL1B protein]; Acetylcysteine inhibits the reaction [Rotenone results in increased expression of IL1B mRNA]; Acetylcysteine inhibits the reaction [Silicon Dioxide analog results in increased secretion of IL1B protein]; Acetylcysteine inhibits the reaction [titanium dioxide results in increased expression of IL1B mRNA]; Acetylcysteine inhibits the reaction [Tobacco Smoke Pollution analog results in increased secretion of IL1B protein]; Acetylcysteine inhibits the reaction [Vehicle Emissions results in increased secretion of IL1B protein]
Acetylcysteine results in decreased expression of IL1B mRNA
Acetylcysteine affects the expression of IL1B protein

PMID:10541287 PMID:11970852 PMID:16014734 PMID:16214328 PMID:18257742 More...

NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415

G

interleukin 2

multiple interactions

[Acetylcysteine results in decreased abundance of Reactive Oxygen Species] which results in decreased expression of IL2 mRNA; Acetylcysteine inhibits the reaction [Mercuric Chloride inhibits the reaction [IL2 protein results in increased phosphorylation of MAPK1 protein]]; Acetylcysteine inhibits the reaction [Mercuric Chloride inhibits the reaction [IL2 protein results in increased phosphorylation of MAPK3 protein]]; Acetylcysteine inhibits the reaction [Mercuric Chloride results in decreased activity of IL2 protein]
Acetylcysteine inhibits the reaction [Fenitrothion results in increased secretion of IL2 protein]

PMID:22429591 PMID:22910795 PMID:31173782

NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566

G

interleukin 24

decreases activity

Acetylcysteine results in decreased activity of IL24 protein

NCBI chr13:42,353,089...42,358,487
Ensembl chr13:42,353,090...42,358,487

G

interleukin 27 receptor subunit alpha

decreases expression

Acetylcysteine results in decreased expression of IL27RA mRNA

NCBI chr19:24,109,963...24,121,977
Ensembl chr19:24,109,972...24,121,938

G

interleukin 2 receptor subunit alpha

multiple interactions

Acetylcysteine inhibits the reaction [di-2-pyridylketone-4,4-dimethyl-3-thiosemicarbazone inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in increased expression of IL2RA protein]]

NCBI chr17:66,849,974...66,898,665
Ensembl chr17:66,849,974...66,898,697

G

interleukin 3

multiple interactions

Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of IL3 protein]

NCBI chr10:38,405,716...38,408,066
Ensembl chr10:38,405,716...38,408,066

G

interleukin 33

multiple interactions

Acetylcysteine promotes the reaction [Soot results in increased expression of IL33 mRNA]

NCBI chr 1:227,701,964...227,736,374
Ensembl chr 1:227,721,435...227,736,373

G

interleukin 4

multiple interactions

Acetylcysteine inhibits the reaction [[CD40LG protein co-treated with IL4 protein] results in increased abundance of Reactive Oxygen Species]; Acetylcysteine inhibits the reaction [[CD40LG protein co-treated with IL4 protein] results in increased expression of TP53 protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of IL4 protein]

PMID:26138014 PMID:27634759

NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750

G

interleukin 4 receptor

multiple interactions

Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of IL4R mRNA]

NCBI chr 1:180,115,061...180,139,981
Ensembl chr 1:180,115,120...180,139,980

G

interleukin 5

multiple interactions

Acetylcysteine inhibits the reaction [Azoxymethane results in increased expression of IL5 protein]
Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of and results in increased secretion of IL5 protein]

PMID:20431929 PMID:26138014

NCBI chr10:37,874,342...37,877,213
Ensembl chr10:37,874,342...37,877,213

G

interleukin 6

multiple interactions
decreases expression

Acetylcysteine analog inhibits the reaction [2-chloroethyl ethyl sulfide results in increased expression of IL6 protein]; Acetylcysteine analog inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein]; Acetylcysteine inhibits the reaction [[Buthionine Sulfoximine co-treated with Lipopolysaccharides] results in increased secretion of IL6 protein]; Acetylcysteine inhibits the reaction [Buthionine Sulfoximine results in increased secretion of IL6 protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of IL6 mRNA]; Acetylcysteine inhibits the reaction [cobaltous chloride results in increased secretion of IL6 protein]; Acetylcysteine inhibits the reaction [Lipopolysaccharides results in increased secretion of IL6 protein]; Acetylcysteine inhibits the reaction [Malathion results in increased expression of IL6 mRNA]; Acetylcysteine inhibits the reaction [Palmitic Acid results in increased expression of IL6 mRNA]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of IL6 protein]; Acetylcysteine inhibits the reaction [Streptozocin results in increased expression of IL6 protein]
Acetylcysteine results in decreased expression of IL6 mRNA
[Acetylcysteine co-treated with Ascorbic Acid] inhibits the reaction [Vehicle Emissions results in increased expression of IL6 mRNA]; Acetylcysteine inhibits the reaction [2,3,5-trichloro-6-phenyl-(1,4)benzoquinone results in increased expression of IL6 protein]; Acetylcysteine inhibits the reaction [Acrolein promotes the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]]; Acetylcysteine inhibits the reaction [Acrolein results in increased expression of IL6 mRNA]; Acetylcysteine inhibits the reaction [Asbestos, Crocidolite results in increased secretion of IL6 protein]; Acetylcysteine inhibits the reaction [cadmium acetate results in increased secretion of IL6 protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of and results in increased secretion of IL6 protein]; Acetylcysteine inhibits the reaction [calcium silicate results in increased secretion of IL6 protein]; Acetylcysteine inhibits the reaction [Chlorine results in decreased secretion of IL6 protein]; Acetylcysteine inhibits the reaction [cobaltous chloride results in increased secretion of IL6 protein]; Acetylcysteine inhibits the reaction [Lipopolysaccharides promotes the reaction [Acrolein results in increased expression of IL6 mRNA]]; Acetylcysteine inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]; Acetylcysteine inhibits the reaction [methylmercuric chloride results in increased expression of IL6 mRNA]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of IL6 mRNA]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of IL6 protein]; Acetylcysteine inhibits the reaction [sodium arsenite results in increased expression of IL6 mRNA]; Acetylcysteine inhibits the reaction [sodium arsenite results in increased secretion of IL6 protein]; Acetylcysteine inhibits the reaction [TGFB1 protein results in increased expression of IL6 protein]; Acetylcysteine inhibits the reaction [TGFB1 protein results in increased secretion of IL6 protein]; Acetylcysteine inhibits the reaction [Tobacco Smoke Pollution results in increased expression of IL6 mRNA]; Acetylcysteine inhibits the reaction [Vehicle Emissions results in increased expression of IL6 mRNA]; Acetylcysteine inhibits the reaction [Vehicle Emissions results in increased expression of IL6 protein]; Acetylcysteine inhibits the reaction [zinc chloride results in increased secretion of IL6 protein]
[Acetylcysteine results in decreased abundance of Reactive Oxygen Species] inhibits the reaction [Lipopolysaccharides promotes the reaction [Polystyrenes results in increased expression of IL6 mRNA]]; [Acetylcysteine results in decreased abundance of Reactive Oxygen Species] inhibits the reaction [Lipopolysaccharides promotes the reaction [Polystyrenes results in increased expression of IL6 protein]]; [Acetylcysteine results in decreased abundance of Reactive Oxygen Species] inhibits the reaction [Polystyrenes promotes the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]]; [Acetylcysteine results in decreased abundance of Reactive Oxygen Species] inhibits the reaction [Polystyrenes promotes the reaction [Lipopolysaccharides results in increased expression of IL6 protein]]; Acetylcysteine inhibits the reaction [27-hydroxycholesterol results in increased expression of IL6 mRNA]; Acetylcysteine inhibits the reaction [27-hydroxycholesterol results in increased secretion of IL6 protein]; Acetylcysteine inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of IL6 mRNA]; Acetylcysteine inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of IL6 protein]; Acetylcysteine inhibits the reaction [[Potassium Dichromate results in increased abundance of chromium hexavalent ion] which results in increased expression of IL6 protein]; Acetylcysteine inhibits the reaction [Acetaminophen results in increased expression of IL6 mRNA]; Acetylcysteine inhibits the reaction [cobaltous chloride results in increased expression of IL6 protein]; Acetylcysteine inhibits the reaction [NOX4 protein promotes the reaction [[Lipopolysaccharides co-treated with IFNG1 protein] results in increased expression of IL6 protein]]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of and results in increased secretion of IL6 protein]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of IL6 mRNA]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of IL6 protein]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased secretion of IL6 protein]; MYD88 protein affects the reaction [Acetylcysteine inhibits the reaction [Particulate Matter results in increased secretion of IL6 protein]]; MYD88 protein affects the reaction [Polymyxin B promotes the reaction [Acetylcysteine inhibits the reaction [Particulate Matter results in increased secretion of IL6 protein]]]; Polymyxin B promotes the reaction [Acetylcysteine inhibits the reaction [Particulate Matter results in increased secretion of IL6 protein]]

PMID:9378980 PMID:10022265 PMID:11970852 PMID:16757516 PMID:17922515 More...

NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178

G

interleukin 7 receptor

multiple interactions

Acetylcysteine inhibits the reaction [Particulate Matter results in decreased expression of IL7R mRNA alternative form]; IL7R mRNA alternative form promotes the reaction [Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of CDKN1A mRNA]]; IL7R mRNA alternative form promotes the reaction [Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of CDKN2A mRNA]]

NCBI chr 2:58,452,393...58,477,757
Ensembl chr 2:58,454,217...58,477,757

G

insulin 1

multiple interactions

Acetylcysteine inhibits the reaction [Cadmium Chloride results in decreased secretion of INS1 protein]; Acetylcysteine inhibits the reaction [Fructose results in increased expression of INS1 protein]; Acetylcysteine inhibits the reaction [tributyltin promotes the reaction [Glucose results in increased secretion of INS1 protein]]
Acetylcysteine inhibits the reaction [Arsenic Trioxide results in decreased secretion of INS1 protein]; Acetylcysteine inhibits the reaction [INS1 protein results in increased expression of CEBPA protein]; Acetylcysteine inhibits the reaction [INS1 protein results in increased expression of FABP4 protein]; Acetylcysteine inhibits the reaction [INS1 protein results in increased expression of PPARG protein]; Acetylcysteine inhibits the reaction [INS1 protein results in increased expression of SLC2A4 protein]; Acetylcysteine inhibits the reaction [INS1 protein results in increased phosphorylation of AKT1 protein]; Acetylcysteine inhibits the reaction [Mercuric Chloride results in decreased secretion of INS1 protein]; Acetylcysteine inhibits the reaction [Methylmercury Compounds results in decreased secretion of INS1 protein]; Acetylcysteine inhibits the reaction [tributyltin promotes the reaction [Glucose results in increased secretion of INS1 protein]]; Acetylcysteine inhibits the reaction [tributyltin results in increased secretion of INS1 protein]

PMID:15680273 PMID:16918248 PMID:20006636 PMID:21145380 PMID:23405080 More...

NCBI chr 1:251,244,973...251,245,540
Ensembl chr 1:251,244,973...251,245,536

G

insulin 2

multiple interactions

Acetylcysteine inhibits the reaction [Glucose results in increased expression of INS protein]; Acetylcysteine inhibits the reaction [tributyltin promotes the reaction [Glucose results in increased secretion of INS protein]]
Acetylcysteine inhibits the reaction [Dexamethasone inhibits the reaction [Glucose results in increased secretion of INS protein]]

PMID:16505238 PMID:21888768 PMID:28180948

NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775

G

insulin induced gene 1

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of INSIG1 mRNA

NCBI chr 4:7,315,494...7,323,972
Ensembl chr 4:7,315,495...7,323,952

G

insulin receptor

multiple interactions

Acetylcysteine inhibits the reaction [Chromium results in decreased phosphorylation of INSR protein]
Acetylcysteine inhibits the reaction [Pyruvaldehyde results in decreased phosphorylation of INSR protein]

PMID:18569013 PMID:22917016

NCBI chr12:1,193,193...1,330,976
Ensembl chr12:1,197,100...1,330,883

G

iron responsive element binding protein 2

multiple interactions

Acetylcysteine inhibits the reaction [Zinc deficiency results in increased expression of IREB2 protein]

NCBI chr 8:55,228,080...55,311,613
Ensembl chr 8:55,228,085...55,311,611

G

interferon regulatory factor 1

multiple interactions

Acetylcysteine inhibits the reaction [nickel sulfate results in increased expression of IRF1 protein]
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of IRF1 mRNA

PMID:20525893 PMID:22129741

NCBI chr10:37,917,155...37,924,166
Ensembl chr10:37,916,670...37,924,166

G

insulin receptor substrate 1

multiple interactions

Acetylcysteine inhibits the reaction [[IGF1 protein co-treated with Estradiol] results in increased phosphorylation of IRS1 protein]

NCBI chr 9:83,552,964...83,605,797
Ensembl chr 9:83,548,944...83,606,122

G

insulin receptor substrate 2

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of IRS2 mRNA

NCBI chr16:78,488,249...78,512,482
Ensembl chr16:78,485,045...78,512,482

G

integrin subunit alpha 2

multiple interactions

Acetylcysteine inhibits the reaction [benz(a)anthracene results in increased expression of ITGA2 mRNA]; Acetylcysteine inhibits the reaction [benzo(k)fluoranthene results in increased expression of ITGA2 mRNA]; Acetylcysteine inhibits the reaction [indeno(1,2,3-cd)pyrene results in increased expression of ITGA2 mRNA]

NCBI chr 2:46,520,345...46,621,487
Ensembl chr 2:46,523,948...46,621,481

G

integrin subunit alpha 2b

multiple interactions

Acetylcysteine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGA2B protein]; Acetylcysteine inhibits the reaction [THPO protein results in increased expression of ITGA2B protein]

NCBI chr10:87,408,532...87,426,055
Ensembl chr10:87,408,536...87,426,168

G

integrin subunit alpha M

multiple interactions

Acetylcysteine inhibits the reaction [3-phenoxybenzoic acid inhibits the reaction [Tretinoin results in increased expression of ITGAM mRNA]]; Acetylcysteine inhibits the reaction [cypermethrin inhibits the reaction [Tretinoin results in increased expression of ITGAM mRNA]]

NCBI chr 1:182,659,047...182,709,501
Ensembl chr 1:182,659,000...182,709,503

G

integrin subunit alpha V

decreases expression

Acetylcysteine results in decreased expression of ITGAV mRNA

NCBI chr 3:68,838,514...68,926,653
Ensembl chr 3:68,838,189...68,926,639

G

integrin subunit beta 1

multiple interactions

Acetylcysteine inhibits the reaction [DDT results in increased expression of ITGB1 mRNA]

NCBI chr19:56,705,123...56,753,199
Ensembl chr19:56,705,171...56,753,195

G

integrin subunit beta 3

multiple interactions

Acetylcysteine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of ITGB3 protein]; Acetylcysteine inhibits the reaction [THPO protein results in increased expression of ITGB3 protein]

NCBI chr10:89,509,917...89,564,679
Ensembl chr10:89,509,989...89,564,679

G

jagged canonical Notch ligand 1

decreases expression
multiple interactions

Acetylcysteine results in decreased expression of JAG1 mRNA
Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of JAG1 mRNA]; Acetylcysteine inhibits the reaction [Vehicle Emissions results in increased expression of JAG1 mRNA]

PMID:16084531 PMID:20974985

NCBI chr 3:124,406,783...124,442,220
Ensembl chr 3:124,406,794...124,442,209

G

Janus kinase 1

multiple interactions

Acetylcysteine inhibits the reaction [DDT results in increased phosphorylation of JAK1 protein]

NCBI chr 5:115,780,248...115,888,841
Ensembl chr 5:115,780,248...115,888,926

G

Janus kinase 2

multiple interactions

Acetylcysteine inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IFNG protein results in increased phosphorylation of and results in increased activity of JAK2 protein]]; Acetylcysteine promotes the reaction [IFNG protein results in increased phosphorylation of and results in increased activity of JAK2 protein]
N-acetyl-L-cysteine inhibits the reaction [hispidulin decreases phoshphorylation of JAK2 protein in colon and colorectum]
N-acetyl-L-cysteine inhibits the reaction [Ginkgoic acid decreases phosphorylation of JAK2 protein in stomach]
N-acetyl-L-cysteine inhibits the reaction [apigenin-7-O-gentiobioside decreases phosphorylation of JAK2 protein in the stomach)
Acetylcysteine inhibits the reaction [Silicon Dioxide results in increased phosphorylation of JAK2 protein]; Acetylcysteine inhibits the reaction [thymoquinone results in decreased phosphorylation of JAK2 protein]

CTD
RGD

PMID:12847270 PMID:29894800 PMID:34627931 PMID:29575334 PMID:32106377 More...

RGD:149735333, RGD:127284886, RGD:127284846

NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189

G

Jun proto-oncogene, AP-1 transcription factor subunit

decreases activity
multiple interactions

Acetylcysteine results in decreased activity of JUN protein
Acetylcysteine inhibits the reaction [2-aminodiphenyl results in increased phosphorylation of and results in increased expression of JUN protein]; Acetylcysteine inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased phosphorylation of JUN protein]; Acetylcysteine inhibits the reaction [8-bromo-7-methoxychrysin results in increased expression of JUN protein]; Acetylcysteine inhibits the reaction [[Copper co-treated with Disulfiram] results in increased phosphorylation of JUN protein]; Acetylcysteine inhibits the reaction [[IGF1 protein co-treated with Estradiol] results in increased expression of JUN protein]; Acetylcysteine inhibits the reaction [afimoxifene results in increased phosphorylation of JUN protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of JUN protein]; Acetylcysteine inhibits the reaction [arsenite results in increased expression of JUN protein]; Acetylcysteine inhibits the reaction [benz(a)anthracene results in increased expression of JUN mRNA]; Acetylcysteine inhibits the reaction [benzo(k)fluoranthene results in increased expression of JUN mRNA]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of JUN]; Acetylcysteine inhibits the reaction [darinaparsin results in increased phosphorylation of JUN protein]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide promotes the reaction [Niclosamide results in increased phosphorylation of JUN protein]]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased expression of JUN protein modified form]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased expression of JUN protein]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased expression of JUN]; Acetylcysteine inhibits the reaction [indeno(1,2,3-cd)pyrene results in increased expression of JUN mRNA]; Acetylcysteine inhibits the reaction [Morphine results in increased phosphorylation of and results in increased activity of JUN protein]; Acetylcysteine inhibits the reaction [Niclosamide results in increased phosphorylation of JUN protein]; Acetylcysteine inhibits the reaction [Silicon Dioxide results in increased phosphorylation of JUN protein]; Acetylcysteine inhibits the reaction [sodium arsenite results in increased expression of JUN protein]
Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of JUN mRNA]; Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of JUN protein]; Acetylcysteine inhibits the reaction [[tungsten carbide co-treated with Cobalt] results in increased localization of and results in increased activity of JUN protein]; Acetylcysteine inhibits the reaction [Asbestos, Crocidolite results in increased expression of JUN mRNA]; Acetylcysteine inhibits the reaction [chromium hexavalent ion results in increased phosphorylation of JUN protein]; Acetylcysteine inhibits the reaction [Chromium results in increased phosphorylation of JUN protein]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased expression of JUN protein modified form]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased expression of JUN protein]; Acetylcysteine inhibits the reaction [maduramicin results in increased phosphorylation of JUN protein]; Acetylcysteine inhibits the reaction [Oxidopamine promotes the reaction [MAPK8 protein binds to and results in increased phosphorylation of JUN protein]]; Acetylcysteine inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of [FOS protein co-treated with JUN protein]]; Acetylcysteine inhibits the reaction [zinc chloride results in increased expression of JUN mRNA]
Acetylcysteine inhibits the reaction [4-hydroxy-2-nonenal results in increased phosphorylation of JUN protein]; Acetylcysteine inhibits the reaction [Asbestos, Crocidolite results in increased expression of JUN mRNA]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of JUN mRNA]; Acetylcysteine inhibits the reaction [Carbon Tetrachloride results in increased expression of JUN mRNA]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased expression of JUN protein modified form]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased expression of JUN protein]; Acetylcysteine inhibits the reaction [methylmercuric chloride results in increased expression of and results in increased phosphorylation of JUN protein]; Acetylcysteine inhibits the reaction [Nitrofurazone results in increased expression of JUN mRNA]; Acetylcysteine promotes the reaction [bis(maltolato)oxovanadium(IV) results in decreased activity of [FOS protein binds to JUN protein]]

PMID:7743507 PMID:8797811 PMID:8825185 PMID:8853906 PMID:9043100 More...

NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656

G

JunB proto-oncogene, AP-1 transcription factor subunit

multiple interactions

Acetylcysteine inhibits the reaction [Asbestos, Crocidolite results in increased expression of JUNB mRNA]

NCBI chr19:23,176,265...23,178,049
Ensembl chr19:23,176,294...23,178,035

G

type I keratin KA11

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of KA11 mRNA

NCBI chr10:85,161,424...85,164,737
Ensembl chr10:85,066,802...85,171,799

G

potassium voltage-gated channel subfamily H member 5

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of KCNH5 mRNA

NCBI chr 6:93,615,174...93,908,107
Ensembl chr 6:93,624,529...93,908,107

G

potassium voltage-gated channel subfamily Q member 5

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of KCNQ5 mRNA
Acetylcysteine inhibits the reaction [sodium arsenite results in decreased expression of KCNQ5 mRNA]

PMID:22129741 PMID:31004932

NCBI chr 9:23,830,185...24,395,984
Ensembl chr 9:23,833,087...24,394,704

G

potassium channel tetramerization domain containing 4

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of KCTD4 mRNA

NCBI chr15:51,263,664...51,278,030
Ensembl chr15:51,274,295...51,277,499

G

lysine demethylase 2A

multiple interactions

Acetylcysteine inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] which results in increased expression of KDM2A protein]
Acetylcysteine inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] promotes the reaction [KDM2A protein binds to CDKN2A promoter]]

NCBI chr 1:201,612,427...201,682,359
Ensembl chr 1:201,612,453...201,680,787

G

kinase insert domain receptor

increases expression

Acetylcysteine results in increased expression of KDR protein

NCBI chr14:32,217,871...32,261,018
Ensembl chr14:32,217,871...32,261,018

G

Kelch-like ECH-associated protein 1

multiple interactions

Acetylcysteine inhibits the reaction [Dinitrochlorobenzene results in increased expression of KEAP1 protein]; Acetylcysteine inhibits the reaction [Indomethacin inhibits the reaction [KEAP1 protein binds to NFE2L2 protein]]
Acetylcysteine inhibits the reaction [Copper Sulfate results in decreased expression of KEAP1 mRNA]; Acetylcysteine inhibits the reaction [Copper Sulfate results in decreased expression of KEAP1 protein]; Acetylcysteine inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of KEAP1 protein]
Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased expression of KEAP1 protein]

PMID:11909699 PMID:19033392 PMID:30104959 PMID:37353053 PMID:37369159

NCBI chr 8:19,768,375...19,777,862
Ensembl chr 8:19,768,375...19,777,862

G

kinesin family member 2C

multiple interactions

Acetylcysteine inhibits the reaction [Hydrogen Peroxide affects the localization of KIF2C protein]

NCBI chr 5:130,637,347...130,662,680
Ensembl chr 5:130,637,347...130,662,637

G

KIT ligand

multiple interactions

Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased secretion of KITLG protein]

NCBI chr 7:34,896,075...34,977,215
Ensembl chr 7:34,896,053...34,977,214

G

Klotho

multiple interactions
increases expression

Acetylcysteine inhibits the reaction [Cyclosporine results in decreased expression of KL protein]
Acetylcysteine results in increased expression of KL protein
Acetylcysteine inhibits the reaction [Indican results in decreased expression of KL mRNA]; Acetylcysteine inhibits the reaction [Indican results in decreased expression of KL protein]

PMID:21389697 PMID:23183129 PMID:23765110

NCBI chr12:490,402...531,417
Ensembl chr12:490,399...530,080

G

KLF transcription factor 4

multiple interactions

Acetylcysteine inhibits the reaction [bisphenol A results in increased expression of KLF4 mRNA]

NCBI chr 5:70,278,843...70,283,751
Ensembl chr 5:70,278,972...70,283,602

G

kallikrein 1-related peptidase C10

multiple interactions

Acetylcysteine inhibits the reaction [SOD2 protein affects the expression of KLK3 mRNA]

NCBI chr 1:94,402,993...94,407,052
Ensembl chr 1:94,402,993...94,407,052

G

lysine methyltransferase 2A

multiple interactions

Acetylcysteine inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] which results in increased expression of KMT2A protein]

NCBI chr 8:45,116,763...45,193,320
Ensembl chr 8:45,118,814...45,193,181

G

KRAS proto-oncogene, GTPase

multiple interactions

Acetylcysteine inhibits the reaction [manumycin results in decreased activity of KRAS protein]

NCBI chr 4:178,185,418...178,218,484

G

kringle containing transmembrane protein 2

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of KREMEN2 mRNA

NCBI chr10:12,763,345...12,767,622
Ensembl chr10:12,763,397...12,767,854

G

keratin 10

multiple interactions

Acetylcysteine inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] which results in increased expression of KRT10 protein]

NCBI chr10:84,338,695...84,343,279
Ensembl chr10:84,338,706...84,343,701

G

keratin 8

multiple interactions

Acetylcysteine inhibits the reaction [Vitamin K 3 results in increased phosphorylation of KRT8 protein]

NCBI chr 7:133,124,203...133,131,656
Ensembl chr 7:133,124,203...133,131,728

G

lysosomal-associated membrane protein 1

multiple interactions

Acetylcysteine inhibits the reaction [cadmium acetate affects the localization of [LAMP1 protein co-treated with MAP1LC3B protein]]
Acetylcysteine affects the reaction [Arsenic Trioxide results in increased expression of LAMP1 mRNA]; Acetylcysteine affects the reaction [Arsenic Trioxide results in increased expression of LAMP1 protein]
Acetylcysteine inhibits the reaction [4-hydroxy-2-nonenal results in increased expression of LAMP1 protein]; Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of LAMP1 mRNA]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of LAMP1 mRNA]

PMID:28347754 PMID:29307831 PMID:31319114 PMID:33462182 PMID:35550146

NCBI chr16:76,355,982...76,380,700
Ensembl chr16:76,355,984...76,381,883

G

lactate dehydrogenase A

multiple interactions

Acetylcysteine inhibits the reaction [1,3-dichloro-2-propanol results in increased secretion of LDHA protein]; Acetylcysteine inhibits the reaction [Isoproterenol results in increased expression of LDHA protein]
Acetylcysteine inhibits the reaction [2,3',4,4',5-pentachlorobiphenyl results in increased expression of LDHA mRNA]; Acetylcysteine inhibits the reaction [2,4,5,2',4',5'-hexachlorobiphenyl results in increased expression of LDHA mRNA]; Acetylcysteine inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of LDHA mRNA]; Acetylcysteine inhibits the reaction [DDT results in increased expression of LDHA mRNA]

PMID:21671307 PMID:30821169 PMID:31251971 PMID:31724279 PMID:36000575

NCBI chr 1:97,371,823...97,381,247
Ensembl chr 1:97,366,021...97,433,472

G

lactate dehydrogenase B

multiple interactions

Acetylcysteine inhibits the reaction [Isoproterenol results in increased expression of LDHB protein]

NCBI chr 4:175,428,382...175,446,403
Ensembl chr 4:175,428,385...175,446,403

G

galectin-like

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of LGALSL mRNA

NCBI chr14:94,996,991...95,004,499
Ensembl chr14:94,996,990...95,004,980

G

luteinizing hormone subunit beta

multiple interactions
increases expression

Acetylcysteine inhibits the reaction [LHB protein results in increased abundance of CEBPB mRNA]; Acetylcysteine inhibits the reaction [LHB protein results in increased abundance of HAS2 mRNA]; Acetylcysteine inhibits the reaction [LHB protein results in increased abundance of PGR mRNA]; Acetylcysteine inhibits the reaction [LHB protein results in increased abundance of PTGS2 mRNA]; Acetylcysteine inhibits the reaction [LHB protein results in increased abundance of TNFAIP6 mRNA]; Acetylcysteine inhibits the reaction [LHB protein results in increased phosphorylation of and results in increased activity of EGFR protein]; Acetylcysteine inhibits the reaction [LHB protein results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Acetylcysteine inhibits the reaction [LHB protein results in increased phosphorylation of and results in increased activity of MAPK3 protein]
Acetylcysteine results in increased expression of LHB protein
Acetylcysteine inhibits the reaction [Sodium Fluoride results in increased expression of LHB protein]

PMID:21220312 PMID:30633982

NCBI chr 1:95,898,269...95,901,973
Ensembl chr 1:95,900,984...95,901,972
Ensembl chr 1:95,900,984...95,901,972

G

LIM homeobox 8

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of LHX8 mRNA

NCBI chr 2:243,244,958...243,269,624
Ensembl chr 2:243,244,961...243,269,416

G

lipase E, hormone sensitive type

multiple interactions

Acetylcysteine inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased phosphorylation of LIPE protein]

NCBI chr 1:80,965,612...80,984,313
Ensembl chr 1:80,965,627...80,984,310

G

lon peptidase 1, mitochondrial

multiple interactions

Acetylcysteine inhibits the reaction [bisphenol A results in increased expression of LONP1 mRNA]

NCBI chr 9:1,447,444...1,459,771
Ensembl chr 9:1,447,447...1,459,771

G

lipin 1

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of LPIN1 mRNA

NCBI chr 6:39,309,198...39,417,034
Ensembl chr 6:39,312,748...39,417,097

G

leucine-rich repeat kinase 2

multiple interactions

Acetylcysteine inhibits the reaction [[Paraquat co-treated with Maneb] results in increased phosphorylation of LRRK2 protein]
Acetylcysteine inhibits the reaction [Cadmium results in increased expression of LRRK2 mRNA]; Acetylcysteine inhibits the reaction [Lead results in increased expression of LRRK2 mRNA]

PMID:34816377 PMID:34897981

NCBI chr 7:122,826,696...122,987,711
Ensembl chr 7:122,826,696...122,987,703

G

lymphocyte antigen 9

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of LY9 mRNA

NCBI chr13:84,079,345...84,100,783
Ensembl chr13:84,079,458...84,100,823

G

lysophospholipase-like 1

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of LYPLAL1 mRNA

NCBI chr13:97,626,568...97,657,901
Ensembl chr13:97,626,451...97,657,867

G

lysozyme-like 4

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of LYZL4 mRNA

NCBI chr 8:121,248,129...121,255,366
Ensembl chr 8:121,248,168...121,255,353

G

mucosal vascular addressin cell adhesion molecule 1

multiple interactions

Acetylcysteine inhibits the reaction [TNF protein results in increased expression of MADCAM1 protein]

NCBI chr 7:10,036,301...10,039,703
Ensembl chr 7:10,036,301...10,039,703

G

microtubule-associated protein 1 light chain 3 beta

multiple interactions
increases expression

Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased metabolism of MAP1LC3B protein]; Acetylcysteine inhibits the reaction [Acrolein results in increased lipidation of MAP1LC3B protein]; Acetylcysteine inhibits the reaction [Apigenin results in increased expression of MAP1LC3B protein modified form]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of MAP1LC3B mRNA]; Acetylcysteine inhibits the reaction [Artesunate results in increased lipidation of MAP1LC3B protein]; Acetylcysteine inhibits the reaction [butein results in increased lipidation of MAP1LC3B protein]; Acetylcysteine inhibits the reaction [cryptotanshinone results in increased expression of MAP1LC3B protein]; Acetylcysteine inhibits the reaction [di-2-pyridylketone-4,4-dimethyl-3-thiosemicarbazone promotes the reaction [bafilomycin A1 results in increased expression of MAP1LC3B protein]]; Acetylcysteine inhibits the reaction [di-n-propyldithiocarbamate results in increased expression of and results in increased lipidation of MAP1LC3B protein]; Acetylcysteine inhibits the reaction [dimethyl alpha-ketoglutarate results in increased lipidation of MAP1LC3B protein]; Acetylcysteine inhibits the reaction [hydroquinone results in increased lipidation of MAP1LC3B protein]; Acetylcysteine inhibits the reaction [ovatodiolide results in increased lipidation of MAP1LC3B protein]; Acetylcysteine inhibits the reaction [sodium arsenite results in increased expression of and results in increased lipidation of MAP1LC3B protein]; Acetylcysteine inhibits the reaction [Vorinostat results in increased cleavage of MAP1LC3B protein]; Acetylcysteine promotes the reaction [Cadmium Chloride results in increased expression of MAP1LC3B protein]; Cadmium Chloride promotes the reaction [Acetylcysteine results in increased expression of MAP1LC3B protein modified form]; Cadmium Chloride promotes the reaction [Acetylcysteine results in increased expression of MAP1LC3B protein]
Acetylcysteine results in increased expression of MAP1LC3B protein; Acetylcysteine results in increased expression of MAP1LC3B protein modified form
Acetylcysteine inhibits the reaction [[Aluminum Chloride results in increased abundance of Aluminum] which results in increased expression of MAP1LC3B mRNA]; Acetylcysteine inhibits the reaction [[Aluminum Chloride results in increased abundance of Aluminum] which results in increased lipidation of MAP1LC3B protein]; Acetylcysteine inhibits the reaction [chromium hexavalent ion affects the expression of and results in increased lipidation of MAP1LC3B protein]; Acetylcysteine inhibits the reaction [cupric chloride results in increased expression of MAP1LC3B protein modified form]; Acetylcysteine inhibits the reaction [Indican results in increased expression of MAP1LC3B protein]; Acetylcysteine inhibits the reaction [Paraquat results in increased expression of MAP1LC3B protein]; Acetylcysteine inhibits the reaction [tricalcium phosphate affects the localization of MAP1LC3B protein]
Acetylcysteine inhibits the reaction [cadmium acetate affects the localization of [LAMP1 protein co-treated with MAP1LC3B protein]]; Acetylcysteine inhibits the reaction [cadmium acetate affects the localization of [RAB7A protein co-treated with MAP1LC3B protein]]; Acetylcysteine inhibits the reaction [nonylphenol results in increased expression of MAP1LC3B protein]

PMID:20543569 PMID:25301941 PMID:27832966 PMID:28347754 PMID:28600121 More...

NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690

G

microtubule-associated protein 2

multiple interactions

Acetylcysteine inhibits the reaction [Particulate Matter results in decreased expression of MAP2 mRNA]
Acetylcysteine inhibits the reaction [Streptozocin results in decreased expression of MAP2 protein]

PMID:28153600 PMID:28499986

NCBI chr 9:67,723,422...67,981,886
Ensembl chr 9:67,723,371...67,979,809

G

mitogen activated protein kinase kinase 1

multiple interactions

Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of MAP2K1 protein]

NCBI chr 8:64,683,449...64,754,900
Ensembl chr 8:64,683,449...64,755,147

G

mitogen activated protein kinase kinase 2

multiple interactions

Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of MAP2K2 protein]

NCBI chr 7:8,590,729...8,610,279
Ensembl chr 7:8,580,905...8,610,243

G

mitogen activated protein kinase kinase 3

multiple interactions

Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of MAP2K3 protein]

NCBI chr10:45,608,145...45,629,492
Ensembl chr10:45,607,163...45,629,492

G

mitogen activated protein kinase kinase 4

multiple interactions

Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of MAP2K4 protein]
N-acetyl-L-cysteine inhibits the reaction [Curcumin increases phosphorylation of MAP2K4 protein in uterine cervix]
Acetylcysteine inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased phosphorylation of MAP2K4 protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of MAP2K4 protein]

CTD
RGD

PMID:18703135 PMID:22085843 PMID:25198898

NCBI chr10:50,343,227...50,447,956
Ensembl chr10:50,344,915...50,447,993

G

mitogen-activated protein kinase kinase 6

multiple interactions

Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of MAP2K6 protein]

NCBI chr10:95,373,304...95,490,406
Ensembl chr10:95,373,204...95,488,293

G

mitogen-activated protein kinase kinase kinase 5

multiple interactions

Acetylcysteine inhibits the reaction [Rotenone inhibits the reaction [TXN protein binds to and results in decreased activity of MAP3K5 protein]]
N-acetyl-L-cysteine co-treated with Curcumin increases phosphorylation of MAP3K5 protein in uterine cervix
Acetylcysteine inhibits the reaction [bisphenol A results in increased phosphorylation of MAP3K5 protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of MAP3K5 protein]; Acetylcysteine inhibits the reaction [platycodin D affects the phosphorylation of and results in increased activity of MAP3K5 protein]; Acetylcysteine inhibits the reaction [Quercetin results in decreased phosphorylation of and results in increased activity of MAP3K5 protein]

CTD
RGD

PMID:16449798 PMID:18703135 PMID:20083342 PMID:22784044 PMID:33039870 More...

NCBI chr 1:14,685,776...14,904,935
Ensembl chr 1:14,685,492...14,904,800

G

mitogen activated protein kinase 1

increases phosphorylation
multiple interactions
decreases phosphorylation

Acetylcysteine results in increased phosphorylation of MAPK1 protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Acetylcysteine results in increased activity of and results in increased phosphorylation of MAPK1 protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Acetylcysteine results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Acetylcysteine affects the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [1,2,5,8-tetrahydroxy anthraquinone results in decreased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [1,4-naphthoquinone analog results in decreased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [2-aminodiphenyl results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [4-(methylthio)-3-butenyl isothiocyanate results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [[IGF1 protein co-treated with Estradiol] results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [[Lipopolysaccharides results in increased abundance of Reactive Oxygen Species] which results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [acacetin results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [Aldosterone results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Acetylcysteine inhibits the reaction [antimony trichloride results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [Arsenic analog results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [Benzo(a)pyrene results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [bisphenol A results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [Butyric Acid results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in decreased expression of and results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [Cadmium results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [Capsaicin results in increased activity of MAPK1 protein]; Acetylcysteine inhibits the reaction [ceric oxide results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [Curcumin results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [Daunorubicin results in decreased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [DDT results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [dihydromyricetin results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [Dinitrochlorobenzene results in decreased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [dorsomorphin results in decreased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [ellipticine results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [Etoposide results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [Fenretinide results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [Homocysteine results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in decreased activity of MAPK1 protein]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [Mercuric Chloride inhibits the reaction [IL2 protein results in increased phosphorylation of MAPK1 protein]]; Acetylcysteine inhibits the reaction [Mercuric Chloride results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [morusin results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [Nicotine results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [Quinacrine results in decreased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [sepantronium results in decreased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [shikonin results in decreased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [tetrabromobisphenol A results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [Thimerosal results in decreased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [Thiostrepton results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [titanium dioxide results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [TNF protein results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [tomentosin results in decreased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [Vehicle Emissions results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [withaferin A results in increased phosphorylation of MAPK1 protein]; Acetylcysteine results in increased activity of and results in increased phosphorylation of MAPK1 protein; Acetylcysteine results in increased phosphorylation of and results in increased activity of MAPK1 protein
Acetylcysteine affects the reaction [Cadmium results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [[cobaltous chloride results in increased abundance of Reactive Oxygen Species] which results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Acetylcysteine inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [Acetaldehyde results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [aureusidin results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased activity of MAPK1 protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [cadmium sulfate results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [chromium hexavalent ion results in increased activity of MAPK1 protein]; Acetylcysteine inhibits the reaction [cobaltous chloride results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Acetylcysteine inhibits the reaction [cobaltous chloride results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [Ditiocarb results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [Doxorubicin results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [EDN1 protein results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [Ethanol results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased expression of MAPK1 protein]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [methylmercuric chloride results in decreased expression of and results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [NGF protein results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [Nickel analog promotes the reaction [PDGFB protein results in increased phosphorylation of MAPK1 protein]]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [pyrrolidine dithiocarbamic acid results in decreased activity of MAPK1 protein]; Acetylcysteine inhibits the reaction [raiser results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [TNF protein results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [Vehicle Emissions results in increased phosphorylation of MAPK1 protein]; U 0126 inhibits the reaction [Acetylcysteine results in increased phosphorylation of MAPK1 protein]
[Acetylcysteine results in decreased abundance of Reactive Oxygen Species] inhibits the reaction [Lipopolysaccharides promotes the reaction [Polystyrenes results in increased expression of MAPK1 mRNA]]; [Acetylcysteine results in decreased abundance of Reactive Oxygen Species] inhibits the reaction [Lipopolysaccharides promotes the reaction [Polystyrenes results in increased phosphorylation of MAPK1 protein]]; [Acetylcysteine results in decreased abundance of Reactive Oxygen Species] inhibits the reaction [Polystyrenes promotes the reaction [Lipopolysaccharides results in increased expression of MAPK1 mRNA]]; [Acetylcysteine results in decreased abundance of Reactive Oxygen Species] inhibits the reaction [Polystyrenes promotes the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK1 protein]]; Acetylcysteine affects the reaction [Phytol promotes the reaction [alpha-MSH results in increased phosphorylation of MAPK1 protein]]; Acetylcysteine inhibits the reaction [1,3-dichloro-2-propanol results in decreased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [[tungsten carbide co-treated with Cobalt] results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Acetylcysteine inhibits the reaction [Acrylamide results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in decreased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [arsenite results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Acetylcysteine inhibits the reaction [Benzo(a)pyrene results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased activity of MAPK1 protein]; Acetylcysteine inhibits the reaction [Cadmium results in increased activity of MAPK1 protein]; Acetylcysteine inhibits the reaction [Endosulfan results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [Indican results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [LHB protein results in increased phosphorylation of and results in increased activity of MAPK1 protein]; Acetylcysteine inhibits the reaction [Methylmercury Compounds results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [Sodium Chloride results in increased phosphorylation of MAPK1 protein]; Acetylcysteine promotes the reaction [Polymyxin B inhibits the reaction [Particulate Matter results in increased phosphorylation of MAPK1 protein]]
Acetylcysteine results in decreased phosphorylation of MAPK1 protein

PMID:8616849 PMID:10658192 PMID:12065697 PMID:12690112 PMID:12717738 More...

NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616

G

mitogen activated protein kinase 10

multiple interactions

Acetylcysteine inhibits the reaction [[Bortezomib co-treated with Butyrates] results in increased phosphorylation of and results in increased activity of MAPK10 protein]; Acetylcysteine inhibits the reaction [[Bortezomib co-treated with vorinostat] results in increased phosphorylation of and results in increased activity of MAPK10 protein]

NCBI chr14:6,497,662...6,790,109
Ensembl chr14:6,497,707...6,786,201

G

mitogen activated protein kinase 13

multiple interactions

Acetylcysteine inhibits the reaction [cholix toxin, Vibrio cholerae results in increased phosphorylation of MAPK13 protein]

NCBI chr20:6,835,277...6,845,500
Ensembl chr20:6,835,320...6,844,222

G

mitogen activated protein kinase 14

multiple interactions

Acetylcysteine inhibits the reaction [[4-hydroxy-2-nonenal co-treated with Hydrogen Peroxide] results in increased activity of MAPK14 protein]; Acetylcysteine inhibits the reaction [[Arsenic Trioxide co-treated with phytosphingosine] results in increased phosphorylation of MAPK14 protein]; Acetylcysteine inhibits the reaction [APP protein results in increased activity of MAPK14 protein]; Acetylcysteine inhibits the reaction [benz(a)anthracene results in increased phosphorylation of MAPK14 protein]; Acetylcysteine inhibits the reaction [benzo(k)fluoranthene results in increased phosphorylation of MAPK14 protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of MAPK14 protein]; Acetylcysteine inhibits the reaction [cholix toxin, Vibrio cholerae results in increased phosphorylation of MAPK14 protein]; Acetylcysteine inhibits the reaction [Emodin promotes the reaction [Arsenic Trioxide results in increased phosphorylation of and results in increased activity of MAPK14 protein]]; Acetylcysteine inhibits the reaction [Homocysteine results in increased phosphorylation of MAPK14 protein]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK14 protein]; Acetylcysteine inhibits the reaction [indeno(1,2,3-cd)pyrene results in increased phosphorylation of MAPK14 protein]; Acetylcysteine inhibits the reaction [TNF protein results in increased phosphorylation of MAPK14 protein]
[Acetylcysteine results in decreased abundance of Reactive Oxygen Species] inhibits the reaction [Lipopolysaccharides promotes the reaction [Polystyrenes results in increased expression of MAPK14 mRNA]]; [Acetylcysteine results in decreased abundance of Reactive Oxygen Species] inhibits the reaction [Polystyrenes promotes the reaction [Lipopolysaccharides results in increased expression of MAPK14 mRNA]]

PMID:12684028 PMID:14729614 PMID:15650392 PMID:17237268 PMID:18703135 More...

NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589

G

mitogen activated protein kinase 3

increases phosphorylation
multiple interactions
decreases phosphorylation

Acetylcysteine results in increased phosphorylation of MAPK3 protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Acetylcysteine results in increased activity of and results in increased phosphorylation of MAPK3 protein]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Acetylcysteine results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Acetylcysteine affects the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [1,2,5,8-tetrahydroxy anthraquinone results in decreased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [1,4-naphthoquinone analog results in decreased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [2-aminodiphenyl results in increased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [4-(methylthio)-3-butenyl isothiocyanate results in increased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [[IGF1 protein co-treated with Estradiol] results in increased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [[Lipopolysaccharides results in increased abundance of Reactive Oxygen Species] which results in increased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [acacetin results in increased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [Aldosterone results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Acetylcysteine inhibits the reaction [antimony trichloride results in increased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [Arsenic analog results in increased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [Benzo(a)pyrene results in increased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [bisphenol A results in increased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [Butyric Acid results in increased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in decreased expression of and results in increased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [Cadmium results in increased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [Capsaicin results in increased activity of MAPK3 protein]; Acetylcysteine inhibits the reaction [ceric oxide results in increased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [Curcumin results in increased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [Daunorubicin results in decreased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [DDT results in increased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [dihydromyricetin results in increased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [Dinitrochlorobenzene results in decreased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [dorsomorphin results in decreased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [ellipticine results in increased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [Etoposide results in increased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [Fenretinide results in increased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [Homocysteine results in increased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased expression of MAPK3 protein modified form]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [Mercuric Chloride inhibits the reaction [IL2 protein results in increased phosphorylation of MAPK3 protein]]; Acetylcysteine inhibits the reaction [Mercuric Chloride results in increased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [morusin results in increased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [Nicotine results in increased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [Quinacrine results in decreased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [sepantronium results in decreased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [shikonin results in decreased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [tetrabromobisphenol A results in increased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [Thimerosal results in decreased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [Thiostrepton results in increased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [titanium dioxide results in increased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [TNF protein results in increased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [tomentosin results in decreased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [Vehicle Emissions results in increased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [withaferin A results in increased phosphorylation of MAPK3 protein]; Acetylcysteine results in increased activity of and results in increased phosphorylation of MAPK3 protein; Acetylcysteine results in increased phosphorylation of and results in increased activity of MAPK3 protein
Acetylcysteine affects the reaction [Cadmium results in increased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [[cobaltous chloride results in increased abundance of Reactive Oxygen Species] which results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Acetylcysteine inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [Acetaldehyde results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [aureusidin results in increased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased activity of MAPK3 protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [cadmium sulfate results in increased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [chromium hexavalent ion results in increased activity of MAPK3 protein]; Acetylcysteine inhibits the reaction [cobaltous chloride results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Acetylcysteine inhibits the reaction [cobaltous chloride results in increased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [Ditiocarb results in increased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [Doxorubicin results in increased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [EDN1 protein results in increased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [Ethanol results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased expression of MAPK3 protein modified form]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased expression of MAPK3 protein]; Acetylcysteine inhibits the reaction [methylmercuric chloride results in decreased expression of and results in increased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [NGF protein results in increased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [Nickel analog promotes the reaction [PDGFB protein results in increased phosphorylation of MAPK3 protein]]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [raiser results in increased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [TNF protein results in increased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [Vehicle Emissions results in increased phosphorylation of MAPK3 protein]; U 0126 inhibits the reaction [Acetylcysteine results in increased phosphorylation of MAPK3 protein]
[Acetylcysteine results in decreased abundance of Reactive Oxygen Species] inhibits the reaction [Lipopolysaccharides promotes the reaction [Polystyrenes results in increased phosphorylation of MAPK3 protein]]; [Acetylcysteine results in decreased abundance of Reactive Oxygen Species] inhibits the reaction [Polystyrenes promotes the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK3 protein]]; Acetylcysteine affects the reaction [Phytol promotes the reaction [alpha-MSH results in increased phosphorylation of MAPK3 protein]]; Acetylcysteine inhibits the reaction [1,3-dichloro-2-propanol results in decreased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [[tungsten carbide co-treated with Cobalt] results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Acetylcysteine inhibits the reaction [Acrylamide results in increased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in decreased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [arsenite results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Acetylcysteine inhibits the reaction [Benzo(a)pyrene results in increased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased activity of MAPK3 protein]; Acetylcysteine inhibits the reaction [Cadmium results in increased activity of MAPK3 protein]; Acetylcysteine inhibits the reaction [Endosulfan results in increased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased expression of MAPK3 protein modified form]; Acetylcysteine inhibits the reaction [Indican results in increased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [LHB protein results in increased phosphorylation of and results in increased activity of MAPK3 protein]; Acetylcysteine inhibits the reaction [Methylmercury Compounds results in increased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [Sodium Chloride results in increased phosphorylation of MAPK3 protein]; Acetylcysteine promotes the reaction [Polymyxin B inhibits the reaction [Particulate Matter results in increased phosphorylation of MAPK3 protein]]
Acetylcysteine results in decreased phosphorylation of MAPK3 protein

PMID:8616849 PMID:12065697 PMID:12690112 PMID:12717738 PMID:14516795 More...

NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863

G

mitogen-activated protein kinase 8

multiple interactions
decreases phosphorylation

Acetylcysteine inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased phosphorylation of MAPK8 protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of MAPK8 protein]; Acetylcysteine inhibits the reaction [aureusidin results in increased phosphorylation of MAPK8 protein]; Acetylcysteine inhibits the reaction [beta-hexachlorocyclohexane results in increased phosphorylation of MAPK8 protein]; Acetylcysteine inhibits the reaction [cadmium sulfate results in increased phosphorylation of MAPK8 protein]; Acetylcysteine inhibits the reaction [cypermethrin results in increased phosphorylation of MAPK8 protein]; Acetylcysteine inhibits the reaction [methylmercuric chloride results in increased phosphorylation of MAPK8 protein]; Acetylcysteine inhibits the reaction [Norepinephrine results in increased phosphorylation of MAPK8 protein]; Acetylcysteine inhibits the reaction [Palmitic Acid results in increased expression of MAPK8 mRNA]; Acetylcysteine inhibits the reaction [Sodium Fluoride results in increased expression of MAPK8 mRNA]
N-acetyl-L-cysteine inhibits the reaction [Curcumin increases phosphorylation of MAPK8 protein in uterine cervix]
Acetylcysteine results in decreased phosphorylation of MAPK8 protein
Acetylcysteine inhibits the reaction [2,3,5-(triglutathion-S-yl)hydroquinone results in increased phosphorylation of and results in increased activity of MAPK8 protein]; Acetylcysteine inhibits the reaction [2-aminodiphenyl results in increased phosphorylation of MAPK8 protein]; Acetylcysteine inhibits the reaction [8-bromo-7-methoxychrysin results in increased phosphorylation of and results in increased activity of MAPK8 protein]; Acetylcysteine inhibits the reaction [[Berberine co-treated with Cisplatin] results in increased phosphorylation of MAPK8 protein]; Acetylcysteine inhibits the reaction [[Bortezomib co-treated with Butyrates] results in increased phosphorylation of and results in increased activity of MAPK8 protein]; Acetylcysteine inhibits the reaction [[Bortezomib co-treated with Vorinostat] results in increased phosphorylation of and results in increased activity of MAPK8 protein]; Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased phosphorylation of MAPK8 protein]; Acetylcysteine inhibits the reaction [[Lipopolysaccharides results in increased abundance of Reactive Oxygen Species] which results in increased phosphorylation of MAPK8 protein]; Acetylcysteine inhibits the reaction [APP protein results in increased activity of MAPK8 protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of MAPK8 protein]; Acetylcysteine inhibits the reaction [Asbestos, Serpentine results in increased phosphorylation of MAPK8 protein]; Acetylcysteine inhibits the reaction [bisphenol A results in increased phosphorylation of MAPK8 protein]; Acetylcysteine inhibits the reaction [butein results in increased phosphorylation of MAPK8 protein]; Acetylcysteine inhibits the reaction [Butyric Acid results in increased phosphorylation of MAPK8 protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of MAPK8 protein]; Acetylcysteine inhibits the reaction [Cadmium results in increased phosphorylation of MAPK8 protein]; Acetylcysteine inhibits the reaction [cholix toxin, Vibrio cholerae results in increased phosphorylation of MAPK8 protein]; Acetylcysteine inhibits the reaction [chromium hexavalent ion results in increased activity of MAPK8 protein]; Acetylcysteine inhibits the reaction [Cisplatin results in increased phosphorylation of MAPK8 protein]; Acetylcysteine inhibits the reaction [cobaltous chloride results in increased phosphorylation of MAPK8 protein]; Acetylcysteine inhibits the reaction [efavirenz metabolite results in increased phosphorylation of MAPK8 protein]; Acetylcysteine inhibits the reaction [efavirenz results in increased phosphorylation of MAPK8 protein]; Acetylcysteine inhibits the reaction [eriocitrin results in increased phosphorylation of MAPK8 protein]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK8 protein]; Acetylcysteine inhibits the reaction [isoliensinine results in increased phosphorylation of MAPK8 protein]; Acetylcysteine inhibits the reaction [longikaurin A results in increased phosphorylation of MAPK8 protein]; Acetylcysteine inhibits the reaction [Silicon Dioxide results in increased phosphorylation of MAPK8 protein]; Acetylcysteine inhibits the reaction [sodium arsenite results in increased phosphorylation of MAPK8 protein]; Acetylcysteine inhibits the reaction [Sodium Selenite results in increased phosphorylation of and results in increased activity of MAPK8 protein]; Acetylcysteine inhibits the reaction [Sodium Selenite results in increased phosphorylation of MAPK8 protein]; Acetylcysteine inhibits the reaction [Spermine results in increased activity of MAPK8 protein]; Acetylcysteine inhibits the reaction [tetrabromobisphenol A results in increased phosphorylation of MAPK8 protein]
[Acetylcysteine results in decreased abundance of Reactive Oxygen Species] inhibits the reaction [Lipopolysaccharides promotes the reaction [Polystyrenes results in increased phosphorylation of MAPK8 protein]]; [Acetylcysteine results in decreased abundance of Reactive Oxygen Species] inhibits the reaction [Polystyrenes promotes the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK8 protein]]; Acetylcysteine inhibits the reaction [1,3-dichloro-2-propanol results in increased phosphorylation of MAPK8 protein]; Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased phosphorylation of MAPK8 protein]; Acetylcysteine inhibits the reaction [Acrylamide results in increased phosphorylation of MAPK8 protein]; Acetylcysteine inhibits the reaction [Biological Products results in increased phosphorylation of MAPK8 protein]; Acetylcysteine inhibits the reaction [cadmium sulfate results in increased phosphorylation of and results in increased activity of MAPK8 protein]; Acetylcysteine inhibits the reaction [chromium hexavalent ion results in increased phosphorylation of MAPK8 protein]; Acetylcysteine inhibits the reaction [Dopamine results in increased phosphorylation of MAPK8 protein]; Acetylcysteine inhibits the reaction [maduramicin results in increased phosphorylation of MAPK8 protein]; Acetylcysteine inhibits the reaction [Oxidopamine promotes the reaction [MAPK8 protein binds to and results in increased phosphorylation of JUN protein]]; Acetylcysteine inhibits the reaction [zinc chloride results in increased activity of MAPK8 protein]

CTD
RGD

PMID:10397638 PMID:11306679 PMID:12684028 PMID:12902192 PMID:14687664 More...

NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981

G

mitogen-activated protein kinase 9

multiple interactions
decreases phosphorylation

[Acetylcysteine results in decreased abundance of Reactive Oxygen Species] inhibits the reaction [Lipopolysaccharides promotes the reaction [Polystyrenes results in increased expression of MAPK9 mRNA]]; [Acetylcysteine results in decreased abundance of Reactive Oxygen Species] inhibits the reaction [Lipopolysaccharides promotes the reaction [Polystyrenes results in increased phosphorylation of MAPK9 protein]]; [Acetylcysteine results in decreased abundance of Reactive Oxygen Species] inhibits the reaction [Polystyrenes promotes the reaction [Lipopolysaccharides results in increased expression of MAPK9 mRNA]]; [Acetylcysteine results in decreased abundance of Reactive Oxygen Species] inhibits the reaction [Polystyrenes promotes the reaction [Lipopolysaccharides results in increased phosphorylation of MAPK9 protein]]; Acetylcysteine inhibits the reaction [1,3-dichloro-2-propanol results in increased phosphorylation of MAPK9 protein]; Acetylcysteine inhibits the reaction [Acrylamide results in increased phosphorylation of MAPK9 protein]; Acetylcysteine inhibits the reaction [Biological Products results in increased phosphorylation of MAPK9 protein]; Acetylcysteine inhibits the reaction [cadmium sulfate results in increased phosphorylation of and results in increased activity of MAPK9 protein]; Acetylcysteine inhibits the reaction [chromium hexavalent ion results in increased phosphorylation of MAPK9 protein]; Acetylcysteine inhibits the reaction [maduramicin results in increased phosphorylation of MAPK9 protein]
Acetylcysteine results in decreased phosphorylation of MAPK9 protein
Acetylcysteine inhibits the reaction [2,3,5-(triglutathion-S-yl)hydroquinone results in increased phosphorylation of and results in increased activity of MAPK9 protein]; Acetylcysteine inhibits the reaction [2-aminodiphenyl results in increased phosphorylation of MAPK9 protein]; Acetylcysteine inhibits the reaction [[Lipopolysaccharides results in increased abundance of Reactive Oxygen Species] which results in increased phosphorylation of MAPK9 protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of MAPK9 protein]; Acetylcysteine inhibits the reaction [Asbestos, Serpentine results in increased phosphorylation of MAPK9 protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of MAPK9 protein]; Acetylcysteine inhibits the reaction [Cadmium results in increased phosphorylation of MAPK9 protein]; Acetylcysteine inhibits the reaction [cobaltous chloride results in increased phosphorylation of MAPK9 protein]; Acetylcysteine inhibits the reaction [longikaurin A results in increased phosphorylation of MAPK9 protein]; Acetylcysteine inhibits the reaction [Silicon Dioxide results in increased phosphorylation of MAPK9 protein]; Acetylcysteine inhibits the reaction [tetrabromobisphenol A results in increased phosphorylation of MAPK9 protein]
Acetylcysteine inhibits the reaction [[Copper co-treated with pyrrolidine dithiocarbamic acid] results in increased phosphorylation of MAPK9 protein]; Acetylcysteine inhibits the reaction [arsenic trioxide results in increased phosphorylation of MAPK9 protein]; Acetylcysteine inhibits the reaction [beta-hexachlorocyclohexane results in increased phosphorylation of MAPK9 protein]; Acetylcysteine inhibits the reaction [cadmium sulfate results in increased phosphorylation of MAPK9 protein]

PMID:14687664 PMID:18412143 PMID:19654923 PMID:19760616 PMID:21135414 More...

NCBI chr10:34,169,661...34,211,138
Ensembl chr10:34,169,675...34,210,178

G

MAPK activated protein kinase 2

multiple interactions

Acetylcysteine inhibits the reaction [sodium arsenite results in increased expression of and results in increased phosphorylation of MAPKAPK2 protein]

NCBI chr13:42,513,762...42,560,061
Ensembl chr13:42,513,762...42,560,457

G

MAPK activated protein kinase 3

multiple interactions

Acetylcysteine inhibits the reaction [[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of MAPKAPK3 mRNA]

NCBI chr 8:107,929,754...107,963,638
Ensembl chr 8:107,929,762...107,963,568

G

microtubule-associated protein tau

multiple interactions

Acetylcysteine inhibits the reaction [cyanoginosin LR results in increased phosphorylation of MAPT protein]
Acetylcysteine inhibits the reaction [1,2-diacetylbenzene results in increased phosphorylation of MAPT protein]

PMID:24142891 PMID:28734998

NCBI chr10:89,138,644...89,236,137
Ensembl chr10:89,138,627...89,236,129

G

MCL1 apoptosis regulator, BCL2 family member

multiple interactions

Acetylcysteine inhibits the reaction [[Bortezomib co-treated with Butyrates] results in decreased expression of MCL1 protein]; Acetylcysteine inhibits the reaction [[Bortezomib co-treated with Vorinostat] results in decreased expression of MCL1 protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide promotes the reaction [Ethacrynic Acid results in decreased expression of MCL1 protein]]; Acetylcysteine inhibits the reaction [dorsomorphin results in decreased expression of MCL1 protein]; Acetylcysteine inhibits the reaction [sepantronium results in decreased expression of MCL1 protein]
Acetylcysteine inhibits the reaction [arsenic trioxide results in decreased expression of MCL1 mRNA]

PMID:15173093 PMID:21533816 PMID:23082001 PMID:31837377 PMID:31900833

NCBI chr 2:183,219,137...183,235,676
Ensembl chr 2:183,219,220...183,222,303

G

minichromosome maintenance 8 homologous recombination repair factor

multiple interactions

Acetylcysteine inhibits the reaction [4-biphenylamine results in decreased expression of MCM8 protein]

NCBI chr 3:120,086,741...120,117,008
Ensembl chr 3:120,086,763...120,117,008

G

malic enzyme 1

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of ME1 mRNA; Acetylcysteine inhibits the reaction [[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of ME1 mRNA]

NCBI chr 8:87,549,043...87,660,251
Ensembl chr 8:87,549,043...87,660,304

G

methyltransferase 14, N6-adenosine-methyltransferase non-catalytic subunit

multiple interactions

Acetylcysteine inhibits the reaction [sodium arsenite results in increased expression of METTL14 mRNA]; Acetylcysteine inhibits the reaction [sodium arsenite results in increased expression of METTL14 protein]
Acetylcysteine inhibits the reaction [Paraquat results in increased expression of METTL14 mRNA]

PMID:31004932 PMID:34425375

NCBI chr 2:211,530,598...211,546,845
Ensembl chr 2:211,530,602...211,546,821

G

methyltransferase 3, N6-adenosine-methyltransferase complex catalytic subunit

multiple interactions

Acetylcysteine inhibits the reaction [sodium arsenite results in increased expression of METTL3 mRNA]
Acetylcysteine inhibits the reaction [Paraquat results in increased expression of METTL3 mRNA]

PMID:31004932 PMID:34425375

NCBI chr15:25,002,505...25,014,097
Ensembl chr15:25,003,172...25,014,041

G

mitofusin 1

multiple interactions

Acetylcysteine inhibits the reaction [Diethylhexyl Phthalate results in decreased expression of MFN1 protein]
Acetylcysteine inhibits the reaction [Polystyrenes analog results in decreased expression of MFN1 protein]
Acetylcysteine inhibits the reaction [Doxorubicin results in decreased expression of MFN1 protein]

PMID:31408635 PMID:37084995 PMID:37499777

NCBI chr 2:115,313,380...115,359,651
Ensembl chr 2:115,313,401...115,359,640

G

mitofusin 2

multiple interactions

Acetylcysteine inhibits the reaction [ALB protein modified form results in decreased expression of MFN2 protein]; Acetylcysteine inhibits the reaction [Doxorubicin results in decreased expression of MFN2 protein]
Acetylcysteine inhibits the reaction [Polystyrenes analog results in decreased expression of MFN2 protein]
Acetylcysteine inhibits the reaction [Diethylhexyl Phthalate results in decreased expression of MFN2 protein]

PMID:27997345 PMID:31408635 PMID:37084995 PMID:37499777

NCBI chr 5:158,304,285...158,335,502
Ensembl chr 5:158,304,287...158,335,342

G

O-6-methylguanine-DNA methyltransferase

multiple interactions
increases expression
decreases activity

Acetylcysteine results in increased expression of and results in increased activity of MGMT protein
Acetylcysteine results in increased expression of MGMT mRNA
Acetylcysteine results in decreased activity of MGMT protein

NCBI chr 1:191,710,980...191,937,760
Ensembl chr 1:191,710,930...191,937,756

G

microRNA 144

multiple interactions

Acetylcysteine inhibits the reaction [Vehicle Emissions results in increased expression of MIR144 mRNA]

NCBI chr10:62,961,348...62,961,430
Ensembl chr10:62,961,348...62,961,430

G

microRNA 21

multiple interactions

Acetylcysteine inhibits the reaction [chromium hexavalent ion results in increased expression of MIR21 mRNA]; Acetylcysteine inhibits the reaction [Vehicle Emissions affects the expression of MIR21 mRNA]

PMID:23584289 PMID:27323401

NCBI chr10:71,405,257...71,405,348
Ensembl chr10:71,405,257...71,405,348

G

microRNA 23b

multiple interactions

Acetylcysteine inhibits the reaction [Acetaminophen results in increased expression of MIR23B mRNA]

NCBI chr17:1,813,667...1,813,763
Ensembl chr17:1,813,667...1,813,763

G

microRNA 28

multiple interactions

Acetylcysteine inhibits the reaction [Acetaminophen results in increased expression of MIR28 mRNA]

NCBI chr11:75,975,523...75,975,608
Ensembl chr11:75,975,523...75,975,608

G

microRNA 761

multiple interactions

Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in decreased expression of MIR761 mRNA]

NCBI chr 5:123,776,534...123,776,609
Ensembl chr 5:123,776,534...123,776,609

G

melanocyte inducing transcription factor

multiple interactions

Acetylcysteine inhibits the reaction [Phytol inhibits the reaction [alpha-MSH results in increased expression of MITF protein]]

NCBI chr 4:130,409,020...130,621,145
Ensembl chr 4:130,409,217...130,621,145

G

marker of proliferation Ki-67

multiple interactions

Acetylcysteine inhibits the reaction [1,12-benzoperylene results in increased expression of MKI67 protein]; Acetylcysteine inhibits the reaction [Particulate Matter results in decreased expression of MKI67 protein]

PMID:31518672 PMID:32745510

NCBI chr 1:190,496,319...190,522,983
Ensembl chr 1:190,496,319...190,522,762

G

modulator of VRAC current 1

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of MLC1 mRNA

NCBI chr 7:120,046,705...120,067,049
Ensembl chr 7:120,046,705...120,067,049

G

mutL homolog 1

multiple interactions

[Acetylcysteine co-treated with Hydrogen Peroxide] results in increased expression of MLH1 mRNA; Acetylcysteine inhibits the reaction [sodium arsenite affects the expression of MLH1 protein]

PMID:28690196 PMID:29854080

NCBI chr 8:111,196,468...111,233,721
Ensembl chr 8:111,196,468...111,233,617

G

mixed lineage kinase domain like pseudokinase

multiple interactions

Acetylcysteine inhibits the reaction [tetrachlorobenzoquinone results in increased expression of MLKL protein]
Acetylcysteine inhibits the reaction [1,3-dichloro-2-propanol results in increased expression of MLKL protein]
[Acetylcysteine results in decreased abundance of Reactive Oxygen Species] inhibits the reaction [Lipopolysaccharides promotes the reaction [Polystyrenes results in increased expression of MLKL mRNA]]; [Acetylcysteine results in decreased abundance of Reactive Oxygen Species] inhibits the reaction [Lipopolysaccharides promotes the reaction [Polystyrenes results in increased expression of MLKL protein]]; [Acetylcysteine results in decreased abundance of Reactive Oxygen Species] inhibits the reaction [Polystyrenes promotes the reaction [Lipopolysaccharides results in increased expression of MLKL mRNA]]; [Acetylcysteine results in decreased abundance of Reactive Oxygen Species] inhibits the reaction [Polystyrenes promotes the reaction [Lipopolysaccharides results in increased expression of MLKL protein]]; Acetylcysteine inhibits the reaction [tricalcium phosphate results in increased phosphorylation of MLKL protein]

PMID:30378427 PMID:35833596 PMID:36000575 PMID:37678662

NCBI chr19:39,277,526...39,304,555
Ensembl chr19:39,276,785...39,304,502

G

matrix metallopeptidase 1

multiple interactions

Acetylcysteine inhibits the reaction [[[[15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of and results in increased activity of HMOX1 protein] which results in increased abundance of Iron] which results in increased abundance of Reactive Oxygen Species] which results in increased expression of MMP1 protein]; Acetylcysteine inhibits the reaction [[Air Pollutants results in increased abundance of Particulate Matter] which results in increased expression of MMP1 mRNA]; Acetylcysteine inhibits the reaction [benzo(k)fluoranthene results in increased expression of MMP1 mRNA]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of MMP1 mRNA]; Acetylcysteine inhibits the reaction [Vehicle Emissions results in increased expression of MMP1 mRNA]

PMID:17449795 PMID:19136476 PMID:21635667 PMID:29731195

NCBI chr 8:4,658,588...4,679,099
Ensembl chr 8:4,658,588...4,679,097

G

matrix metallopeptidase 10

multiple interactions

Acetylcysteine inhibits the reaction [FN1 protein modified form results in increased expression of and results in increased secretion of MMP10 protein]

NCBI chr 8:4,689,840...4,697,748
Ensembl chr 8:4,689,840...4,697,748

G

matrix metallopeptidase 12

multiple interactions

Acetylcysteine inhibits the reaction [Ethanol results in increased expression of MMP12 mRNA]

NCBI chr 8:4,581,785...4,591,687
Ensembl chr 8:4,581,785...4,599,611

G

matrix metallopeptidase 13

multiple interactions

Acetylcysteine inhibits the reaction [FN1 protein modified form results in increased expression of and results in increased secretion of MMP13 protein]; Acetylcysteine inhibits the reaction [Lipopolysaccharides results in increased expression of MMP13 protein]; Quercetin promotes the reaction [Acetylcysteine inhibits the reaction [Lipopolysaccharides results in increased expression of MMP13 protein]]

PMID:17395008 PMID:34791735

NCBI chr 8:4,497,960...4,508,239
Ensembl chr 8:4,497,960...4,508,239

G

matrix metallopeptidase 2

multiple interactions
decreases activity

Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of MMP2 mRNA]; Acetylcysteine inhibits the reaction [Doxorubicin results in increased expression of MMP2 mRNA]
Acetylcysteine inhibits the reaction [Arsenic Trioxide results in decreased expression of MMP2 mRNA]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in decreased secretion of MMP2 protein]; Acetylcysteine inhibits the reaction [benz(a)anthracene results in increased expression of MMP2 mRNA]; Acetylcysteine inhibits the reaction [indeno(1,2,3-cd)pyrene results in increased expression of MMP2 mRNA]; Acetylcysteine inhibits the reaction [tomentosin results in decreased activity of MMP2 protein]
Acetylcysteine results in decreased activity of MMP2 protein

PMID:15451797 PMID:15962302 PMID:16213474 PMID:21540248 PMID:21635667 More...

NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870

G

matrix metallopeptidase 25

multiple interactions

Acetylcysteine inhibits the reaction [benzo(k)fluoranthene results in increased expression of MMP25 mRNA]

NCBI chr10:12,661,297...12,676,119
Ensembl chr10:12,661,208...12,675,871

G

matrix metallopeptidase 3

multiple interactions

Acetylcysteine inhibits the reaction [FN1 protein modified form results in increased expression of and results in increased secretion of MMP3 protein]; Acetylcysteine inhibits the reaction [Lipopolysaccharides results in increased expression of MMP3 protein]; Quercetin promotes the reaction [Acetylcysteine inhibits the reaction [Lipopolysaccharides results in increased expression of MMP3 protein]]

PMID:17395008 PMID:34791735

NCBI chr 8:4,640,397...4,653,963
Ensembl chr 8:4,640,416...4,653,961

G

matrix metallopeptidase 7

multiple interactions

Acetylcysteine inhibits the reaction [epigallocatechin gallate results in increased expression of MMP7 protein]; Acetylcysteine inhibits the reaction [Tretinoin results in increased expression of MMP7 mRNA]

NCBI chr 8:4,848,186...4,855,908
Ensembl chr 8:4,848,186...4,855,902

G

matrix metallopeptidase 9

multiple interactions
decreases activity

Acetylcysteine inhibits the reaction [4-aminophenylmercuriacetate results in increased activity of MMP9 protein]; Acetylcysteine inhibits the reaction [Acrolein results in increased expression of MMP9 protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in decreased expression of MMP9 mRNA]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in decreased secretion of MMP9 protein]; Acetylcysteine inhibits the reaction [bisphenol A results in increased expression of MMP9 mRNA]; Acetylcysteine inhibits the reaction [bisphenol A results in increased expression of MMP9 protein]; Acetylcysteine inhibits the reaction [Chlorine results in decreased secretion of MMP9 protein]; Acetylcysteine inhibits the reaction [Homocysteine results in increased activity of MMP9 protein]; Acetylcysteine inhibits the reaction [Homocysteine results in increased expression of MMP9 protein]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased expression of MMP9 mRNA]; Acetylcysteine inhibits the reaction [Oxidopamine results in increased expression of MMP9 mRNA]; Acetylcysteine inhibits the reaction [tetrabromobisphenol A results in increased expression of MMP9 mRNA]
Acetylcysteine results in decreased activity of MMP9 protein
[Ethanol co-treated with Dietary Fats co-treated with Acetylcysteine] results in increased expression of MMP9 mRNA; Acetylcysteine inhibits the reaction [Doxorubicin results in increased expression of MMP9 mRNA]; Acetylcysteine inhibits the reaction [Ethanol results in increased secretion of and results in increased activity of MMP9 protein]; Acetylcysteine inhibits the reaction [RELA protein binds to MMP9 promoter]; Acetylcysteine inhibits the reaction [TNF protein results in increased expression of and results in increased secretion of MMP9 protein]; Acetylcysteine inhibits the reaction [TNF protein results in increased expression of MMP9 mRNA]
Acetylcysteine inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of MMP9 mRNA]; Acetylcysteine inhibits the reaction [Lipopolysaccharides results in increased expression of MMP9 mRNA]

PMID:15451797 PMID:15557194 PMID:15962302 PMID:16213474 PMID:16251475 More...

NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120

G

modulator of apoptosis 1

decreases expression

Acetylcysteine results in decreased expression of MOAP1 mRNA

NCBI chr 6:121,882,565...121,884,500
Ensembl chr 6:121,882,366...121,898,643

G

Mov10 like RNA helicase 1

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of MOV10L1 mRNA

NCBI chr 7:120,070,171...120,135,406
Ensembl chr 7:120,070,135...120,134,765

G

myeloperoxidase

multiple interactions

[MPO protein co-treated with XDH protein co-treated with Acetaldehyde] promotes the reaction [Serotonin binds to Acetylcysteine]; Acetylcysteine promotes the reaction [[MPO protein results in increased oxidation of dibromoacetonitrile] which results in increased chemical synthesis of Cyanides]; Acetylcysteine promotes the reaction [MPO protein results in increased oxidation of dibromoacetonitrile]
Acetylcysteine inhibits the reaction [arachidonyl-2-chloroethylamide results in increased activity of MPO protein]
Acetylcysteine inhibits the reaction [Ethanol results in increased activity of MPO protein]; Acetylcysteine inhibits the reaction [Gentamicins results in increased activity of MPO protein]; Acetylcysteine inhibits the reaction [Malathion results in increased activity of MPO protein]; Acetylcysteine inhibits the reaction [Methotrexate results in increased expression of MPO protein]; Acetylcysteine inhibits the reaction [Nicotine results in increased activity of MPO protein]; Acetylcysteine inhibits the reaction [Paraquat promotes the reaction [Zinc Sulfate results in increased activity of MPO protein]]; Acetylcysteine inhibits the reaction [Paraquat results in increased activity of MPO protein]; Acetylcysteine inhibits the reaction [Smoke results in increased activity of MPO protein]; Acetylcysteine inhibits the reaction [Zinc Sulfate promotes the reaction [Paraquat results in increased activity of MPO protein]]; Acetylcysteine inhibits the reaction [Zinc Sulfate results in increased activity of MPO protein]; Acetylcysteine promotes the reaction [EUK-134 inhibits the reaction [Paraquat promotes the reaction [Zinc Sulfate results in increased activity of MPO protein]]]; Acetylcysteine promotes the reaction [EUK-134 inhibits the reaction [Paraquat results in increased activity of MPO protein]]; Acetylcysteine promotes the reaction [EUK-134 inhibits the reaction [Zinc Sulfate promotes the reaction [Paraquat results in increased activity of MPO protein]]]; Acetylcysteine promotes the reaction [EUK-134 inhibits the reaction [Zinc Sulfate results in increased activity of MPO protein]]; EUK-134 promotes the reaction [Acetylcysteine inhibits the reaction [Paraquat promotes the reaction [Zinc Sulfate results in increased activity of MPO protein]]]; EUK-134 promotes the reaction [Acetylcysteine inhibits the reaction [Paraquat results in increased activity of MPO protein]]; EUK-134 promotes the reaction [Acetylcysteine inhibits the reaction [Zinc Sulfate promotes the reaction [Paraquat results in increased activity of MPO protein]]]; EUK-134 promotes the reaction [Acetylcysteine inhibits the reaction [Zinc Sulfate results in increased activity of MPO protein]]

PMID:11470263 PMID:17216608 PMID:17603938 PMID:20885979 PMID:22664789 More...

NCBI chr10:72,594,883...72,608,862
Ensembl chr10:72,594,661...72,604,819

G

melanocortin 2 receptor accessory protein

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of MRAP mRNA

NCBI chr11:29,991,974...30,003,024
Ensembl chr11:29,992,034...30,003,024

G

mannose receptor, C type 1

multiple interactions

[Paraquat co-treated with Acetylcysteine] results in decreased expression of MRC1 mRNA; [Paraquat co-treated with Acetylcysteine] results in decreased expression of MRC1 protein

NCBI chr17:77,249,187...77,330,857
Ensembl chr17:77,249,187...77,330,857

G

membrane spanning 4-domains A8

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of MS4A8A mRNA

NCBI chr 1:207,730,665...207,744,260
Ensembl chr 1:207,730,665...207,744,324

G

mesogenin 1

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of MSGN1 mRNA

NCBI chr 6:33,912,787...33,913,427
Ensembl chr 6:33,912,787...33,913,427

G

mutS homolog 2

multiple interactions

Acetylcysteine affects the reaction [Cadmium Chloride results in decreased expression of MSH2 protein]; Acetylcysteine inhibits the reaction [Acetaminophen results in increased expression of MSH2 mRNA]; Acetylcysteine inhibits the reaction [sodium arsenite affects the expression of MSH2 protein]

PMID:28690196 PMID:33971260

NCBI chr 6:6,813,793...6,872,960
Ensembl chr 6:6,813,795...6,872,938

G

mutS homolog 6

multiple interactions

Acetylcysteine inhibits the reaction [Cadmium Chloride results in decreased expression of MSH6 protein]; Acetylcysteine inhibits the reaction [sodium arsenite results in decreased expression of MSH6 protein]

NCBI chr 6:6,562,631...6,579,995
Ensembl chr 6:6,562,632...6,579,956

G

methionine sulfoxide reductase B1

multiple interactions

Acetylcysteine inhibits the reaction [bisphenol A results in increased expression of MSRB1 mRNA]

NCBI chr10:13,764,883...13,770,609
Ensembl chr10:13,764,883...13,770,609

G

myostatin

decreases expression

Acetylcysteine results in decreased expression of MSTN mRNA; Acetylcysteine results in decreased expression of MSTN protein

NCBI chr 9:48,452,533...48,458,933
Ensembl chr 9:48,452,533...48,458,933

G

mitochondrially encoded ATP synthase membrane subunit 6

multiple interactions

Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in decreased expression of ATP6 mRNA]

NCBI chr MT:7,919...8,599
NCBI chr MT:7,919...8,599
NCBI chr MT:7,919...8,599
Ensembl chr MT:7,919...8,599

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mitochondrially encoded ATP synthase membrane subunit 8

multiple interactions

Acetylcysteine inhibits the reaction [sodium bisulfite results in decreased expression of ATP8 mRNA]

NCBI chr MT:7,758...7,961
NCBI chr MT:7,758...7,961
NCBI chr MT:7,758...7,961
Ensembl chr MT:7,758...7,961

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mitochondrially encoded cytochrome c oxidase I

multiple interactions

Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in decreased expression of COX1 mRNA]; Acetylcysteine inhibits the reaction [sodium bisulfite results in decreased expression of COX1 mRNA]

PMID:26980303 PMID:30104959

NCBI chr MT:5,323...6,867
NCBI chr MT:5,323...6,867
NCBI chr MT:5,323...6,867
Ensembl chr MT:5,323...6,867

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mitochondrially encoded cytochrome b

multiple interactions

Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in decreased expression of CYTB mRNA]
Acetylcysteine promotes the reaction [XRCC1 protein results in increased expression of CYTB mRNA]

PMID:30104959 PMID:30998386

NCBI chr MT:14,136...15,278
NCBI chr MT:14,136...15,278
NCBI chr MT:14,136...15,278
NCBI chr MT:14,136...15,278
Ensembl chr MT:14,136...15,278

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mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 1

multiple interactions

Acetylcysteine inhibits the reaction [Monocrotophos results in decreased expression of ND1 mRNA]

NCBI chr MT:2,740...3,694
NCBI chr MT:2,740...3,694
NCBI chr MT:2,740...3,694
NCBI chr MT:2,740...3,694
Ensembl chr MT:2,740...3,694

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mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 2

multiple interactions

Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in decreased expression of ND2 mRNA]; Acetylcysteine inhibits the reaction [Monocrotophos results in decreased expression of ND2 mRNA]
Acetylcysteine promotes the reaction [XRCC1 protein results in increased expression of ND2 mRNA]

PMID:30104959 PMID:30998386 PMID:35403558

NCBI chr MT:3,904...4,942
NCBI chr MT:3,904...4,942
NCBI chr MT:3,904...4,942
NCBI chr MT:3,904...4,942
Ensembl chr MT:3,904...4,942

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mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 5

multiple interactions

Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in decreased expression of ND5 mRNA]
Acetylcysteine promotes the reaction [XRCC1 protein results in increased expression of ND5 mRNA]

PMID:30104959 PMID:30998386

NCBI chr MT:11,736...13,565
NCBI chr MT:11,736...13,565
NCBI chr MT:11,736...13,565
Ensembl chr MT:11,736...13,565

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metallothionein 1

multiple interactions

Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of MT1A mRNA]; Acetylcysteine inhibits the reaction [Paraquat promotes the reaction [Zinc Sulfate results in increased expression of MT1A mRNA]]; Acetylcysteine inhibits the reaction [Paraquat promotes the reaction [Zinc Sulfate results in increased expression of MT1A protein]]; Acetylcysteine inhibits the reaction [Paraquat results in increased expression of MT1A mRNA]; Acetylcysteine inhibits the reaction [Paraquat results in increased expression of MT1A protein]; Acetylcysteine inhibits the reaction [Zinc Sulfate promotes the reaction [Paraquat results in increased expression of MT1A mRNA]]; Acetylcysteine inhibits the reaction [Zinc Sulfate promotes the reaction [Paraquat results in increased expression of MT1A protein]]; Acetylcysteine inhibits the reaction [Zinc Sulfate results in increased expression of MT1A mRNA]; Acetylcysteine inhibits the reaction [Zinc Sulfate results in increased expression of MT1A protein]; Acetylcysteine promotes the reaction [EUK-134 inhibits the reaction [Paraquat promotes the reaction [Zinc Sulfate results in increased expression of MT1A mRNA]]]; Acetylcysteine promotes the reaction [EUK-134 inhibits the reaction [Paraquat promotes the reaction [Zinc Sulfate results in increased expression of MT1A protein]]]; Acetylcysteine promotes the reaction [EUK-134 inhibits the reaction [Paraquat results in increased expression of MT1A mRNA]]; Acetylcysteine promotes the reaction [EUK-134 inhibits the reaction [Paraquat results in increased expression of MT1A protein]]; Acetylcysteine promotes the reaction [EUK-134 inhibits the reaction [Zinc Sulfate promotes the reaction [Paraquat results in increased expression of MT1A mRNA]]]; Acetylcysteine promotes the reaction [EUK-134 inhibits the reaction [Zinc Sulfate promotes the reaction [Paraquat results in increased expression of MT1A protein]]]; Acetylcysteine promotes the reaction [EUK-134 inhibits the reaction [Zinc Sulfate results in increased expression of MT1A mRNA]]; Acetylcysteine promotes the reaction [EUK-134 inhibits the reaction [Zinc Sulfate results in increased expression of MT1A protein]]; EUK-134 promotes the reaction [Acetylcysteine inhibits the reaction [Paraquat promotes the reaction [Zinc Sulfate results in increased expression of MT1A mRNA]]]; EUK-134 promotes the reaction [Acetylcysteine inhibits the reaction [Paraquat promotes the reaction [Zinc Sulfate results in increased expression of MT1A protein]]]; EUK-134 promotes the reaction [Acetylcysteine inhibits the reaction [Paraquat results in increased expression of MT1A mRNA]]; EUK-134 promotes the reaction [Acetylcysteine inhibits the reaction [Paraquat results in increased expression of MT1A protein]]; EUK-134 promotes the reaction [Acetylcysteine inhibits the reaction [Zinc Sulfate promotes the reaction [Paraquat results in increased expression of MT1A mRNA]]]; EUK-134 promotes the reaction [Acetylcysteine inhibits the reaction [Zinc Sulfate promotes the reaction [Paraquat results in increased expression of MT1A protein]]]; EUK-134 promotes the reaction [Acetylcysteine inhibits the reaction [Zinc Sulfate results in increased expression of MT1A mRNA]]; EUK-134 promotes the reaction [Acetylcysteine inhibits the reaction [Zinc Sulfate results in increased expression of MT1A protein]]

PMID:9152014 PMID:25724285

NCBI chr19:10,826,032...10,827,048
Ensembl chr19:10,826,032...10,827,049
Ensembl chr17:10,826,032...10,827,049

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metallothionein 1, pseudogene 3

multiple interactions

Acetylcysteine inhibits the reaction [elesclomol results in increased expression of MT1E mRNA]

NCBI chr17:74,786,652...74,787,040
Ensembl chr17:74,786,654...74,787,135

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metallothionein 2A

multiple interactions
decreases expression

Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of MT2A mRNA]; Acetylcysteine inhibits the reaction [gallium nitrate results in increased expression of MT2A mRNA]; Acetylcysteine inhibits the reaction [Nickel results in increased expression of MT2A mRNA]
Acetylcysteine results in decreased expression of MT2A mRNA
Acetylcysteine inhibits the reaction [[[Cadmium Chloride results in increased abundance of Cadmium] which co-treated with hydroquinone] results in increased expression of MT2A mRNA]; Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of MT2A mRNA]; Acetylcysteine inhibits the reaction [hydroquinone results in increased expression of MT2A mRNA]; Acetylcysteine inhibits the reaction [Paraquat promotes the reaction [Zinc Sulfate results in increased expression of MT2A mRNA]]; Acetylcysteine inhibits the reaction [Paraquat promotes the reaction [Zinc Sulfate results in increased expression of MT2A protein]]; Acetylcysteine inhibits the reaction [Paraquat results in increased expression of MT2A mRNA]; Acetylcysteine inhibits the reaction [Paraquat results in increased expression of MT2A protein]; Acetylcysteine inhibits the reaction [Zinc Sulfate promotes the reaction [Paraquat results in increased expression of MT2A mRNA]]; Acetylcysteine inhibits the reaction [Zinc Sulfate promotes the reaction [Paraquat results in increased expression of MT2A protein]]; Acetylcysteine inhibits the reaction [Zinc Sulfate results in increased expression of MT2A mRNA]; Acetylcysteine inhibits the reaction [Zinc Sulfate results in increased expression of MT2A protein]; Acetylcysteine promotes the reaction [EUK-134 inhibits the reaction [Paraquat promotes the reaction [Zinc Sulfate results in increased expression of MT2A mRNA]]]; Acetylcysteine promotes the reaction [EUK-134 inhibits the reaction [Paraquat promotes the reaction [Zinc Sulfate results in increased expression of MT2A protein]]]; Acetylcysteine promotes the reaction [EUK-134 inhibits the reaction [Paraquat results in increased expression of MT2A mRNA]]; Acetylcysteine promotes the reaction [EUK-134 inhibits the reaction [Paraquat results in increased expression of MT2A protein]]; Acetylcysteine promotes the reaction [EUK-134 inhibits the reaction [Zinc Sulfate promotes the reaction [Paraquat results in increased expression of MT2A mRNA]]]; Acetylcysteine promotes the reaction [EUK-134 inhibits the reaction [Zinc Sulfate promotes the reaction [Paraquat results in increased expression of MT2A protein]]]; Acetylcysteine promotes the reaction [EUK-134 inhibits the reaction [Zinc Sulfate results in increased expression of MT2A mRNA]]; Acetylcysteine promotes the reaction [EUK-134 inhibits the reaction [Zinc Sulfate results in increased expression of MT2A protein]]; EUK-134 promotes the reaction [Acetylcysteine inhibits the reaction [Paraquat promotes the reaction [Zinc Sulfate results in increased expression of MT2A mRNA]]]; EUK-134 promotes the reaction [Acetylcysteine inhibits the reaction [Paraquat promotes the reaction [Zinc Sulfate results in increased expression of MT2A protein]]]; EUK-134 promotes the reaction [Acetylcysteine inhibits the reaction [Paraquat results in increased expression of MT2A mRNA]]; EUK-134 promotes the reaction [Acetylcysteine inhibits the reaction [Paraquat results in increased expression of MT2A protein]]; EUK-134 promotes the reaction [Acetylcysteine inhibits the reaction [Zinc Sulfate promotes the reaction [Paraquat results in increased expression of MT2A mRNA]]]; EUK-134 promotes the reaction [Acetylcysteine inhibits the reaction [Zinc Sulfate promotes the reaction [Paraquat results in increased expression of MT2A protein]]]; EUK-134 promotes the reaction [Acetylcysteine inhibits the reaction [Zinc Sulfate results in increased expression of MT2A mRNA]]; EUK-134 promotes the reaction [Acetylcysteine inhibits the reaction [Zinc Sulfate results in increased expression of MT2A protein]]
[MT1 protein co-treated with MT2 protein] affects the reaction [Acetylcysteine affects the susceptibility to Doxorubicin]

PMID:9545559 PMID:18586083 PMID:19097988 PMID:20600803 PMID:25724285 More...

NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784

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mechanistic target of rapamycin kinase

multiple interactions

Acetylcysteine inhibits the reaction [4-nonylphenol results in decreased phosphorylation of MTOR protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of MTOR protein]
Acetylcysteine inhibits the reaction [Paraquat results in decreased phosphorylation of MTOR protein]; Acetylcysteine inhibits the reaction [Polystyrenes analog results in increased phosphorylation of MTOR protein]; Acetylcysteine inhibits the reaction [Zearalenone results in decreased phosphorylation of MTOR protein]
Acetylcysteine inhibits the reaction [Antimycin A results in increased expression of MTOR mRNA]; Acetylcysteine inhibits the reaction [Artesunate results in decreased phosphorylation of MTOR protein]; Acetylcysteine inhibits the reaction [Biological Products results in decreased expression of MTOR protein modified form]; Acetylcysteine inhibits the reaction [butein results in decreased phosphorylation of MTOR protein]; Acetylcysteine inhibits the reaction [Butyric Acid results in decreased phosphorylation of MTOR protein]; Acetylcysteine inhibits the reaction [Cannabidiol results in decreased phosphorylation of MTOR protein]; Acetylcysteine inhibits the reaction [cucurbitacin E results in decreased phosphorylation of MTOR protein]; Acetylcysteine inhibits the reaction [Estradiol results in increased phosphorylation of MTOR protein]; Acetylcysteine inhibits the reaction [ginsenoside Rk1 results in decreased phosphorylation of MTOR protein]; Acetylcysteine inhibits the reaction [hydroquinone results in decreased phosphorylation of MTOR protein]; Acetylcysteine inhibits the reaction [Patulin results in decreased phosphorylation of MTOR protein]; Acetylcysteine inhibits the reaction [tris(1,3-dichloro-2-propyl)phosphate results in decreased phosphorylation of MTOR protein]

PMID:21195169 PMID:23000059 PMID:26804764 PMID:27106530 PMID:28025121 More...

NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311

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5-methyltetrahydrofolate-homocysteine methyltransferase

multiple interactions

Acetylcysteine inhibits the reaction [bisphenol A results in increased expression of MTR mRNA]

NCBI chr17:58,219,998...58,308,560
Ensembl chr17:58,220,071...58,304,822

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mucin 5AC, oligomeric mucus/gel-forming

multiple interactions

Acetylcysteine inhibits the reaction [2,2',4,4'-tetrabromodiphenyl ether results in increased expression of MUC5AC mRNA]; Acetylcysteine inhibits the reaction [2,2',4,4'-tetrabromodiphenyl ether results in increased expression of MUC5AC protein]; Acetylcysteine inhibits the reaction [Benzo(a)pyrene results in increased expression of MUC5AC mRNA]; Acetylcysteine inhibits the reaction [Benzo(a)pyrene results in increased expression of MUC5AC protein]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased expression of MUC5AC protein]; Acetylcysteine inhibits the reaction [Paraquat results in increased expression of MUC5AC mRNA]

PMID:10640773 PMID:20709182 PMID:25177032 PMID:31622892 PMID:33421718

NCBI chr 1:196,864,336...196,896,475
Ensembl chr 1:196,864,336...196,896,475

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mucin 5B, oligomeric mucus/gel-forming

multiple interactions

Acetylcysteine inhibits the reaction [decabromobiphenyl ether results in increased expression of MUC5B mRNA]; Acetylcysteine inhibits the reaction [decabromobiphenyl ether results in increased expression of MUC5B protein]

NCBI chr 1:196,916,861...196,948,830
Ensembl chr 1:196,916,825...196,949,250

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mucin 6, oligomeric mucus/gel-forming

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of MUC6 mRNA

NCBI chr 1:196,726,678...196,764,842
Ensembl chr 1:196,726,807...196,764,842

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MX dynamin like GTPase 1

multiple interactions

Acetylcysteine inhibits the reaction [Dieldrin inhibits the reaction [Poly I-C results in increased expression of MX1 mRNA]]

NCBI chr11:36,799,659...36,825,209
Ensembl chr11:36,799,660...36,823,507

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MYC proto-oncogene, bHLH transcription factor

multiple interactions

Acetylcysteine inhibits the reaction [5-nitroso-8-quinolinol results in decreased expression of MYC protein]; Acetylcysteine inhibits the reaction [[Arsenic Trioxide co-treated with Cisplatin] results in decreased expression of MYC protein]; Acetylcysteine inhibits the reaction [Hydrocarbons, Chlorinated analog results in increased expression of MYC protein]; Acetylcysteine inhibits the reaction [Zinc deficiency results in decreased expression of MYC protein]
Acetylcysteine inhibits the reaction [[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of MYC mRNA]; Acetylcysteine inhibits the reaction [Glyphosate results in increased expression of MYC mRNA]; Acetylcysteine inhibits the reaction [Nitrofurazone results in increased expression of MYC mRNA]

PMID:15945272 PMID:16497787 PMID:21600978 PMID:22129741 PMID:24355586 More...

NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630

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Mycbp associated protein

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of MYCBPAP mRNA; Acetylcysteine inhibits the reaction [[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of MYCBPAP mRNA]

NCBI chr10:79,450,319...79,470,977
Ensembl chr10:79,450,324...79,470,828

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MYD88, innate immune signal transduction adaptor

multiple interactions

[Particulate Matter co-treated with Acetylcysteine co-treated with Polymyxin B] results in increased secretion of MYD88 protein; [Particulate Matter co-treated with Acetylcysteine] results in increased secretion of MYD88 protein; Acetylcysteine inhibits the reaction [benzanthrone results in increased expression of MYD88 protein]; Acetylcysteine inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of MYD88 mRNA]; MYD88 protein affects the reaction [[Acetylcysteine co-treated with Particulate Matter] results in increased secretion of CCL3 protein]; MYD88 protein affects the reaction [[Particulate Matter co-treated with Acetylcysteine co-treated with Polymyxin B] results in increased secretion of MYD88 protein]; MYD88 protein affects the reaction [[Particulate Matter co-treated with Acetylcysteine] results in increased secretion of MYD88 protein]; MYD88 protein affects the reaction [Acetylcysteine inhibits the reaction [Particulate Matter results in increased secretion of CXCL1 protein]]; MYD88 protein affects the reaction [Acetylcysteine inhibits the reaction [Particulate Matter results in increased secretion of IL6 protein]]; MYD88 protein affects the reaction [Acetylcysteine inhibits the reaction [Particulate Matter results in increased secretion of TNF protein]]; MYD88 protein affects the reaction [Polymyxin B promotes the reaction [Acetylcysteine inhibits the reaction [Particulate Matter results in increased secretion of CXCL1 protein]]]; MYD88 protein affects the reaction [Polymyxin B promotes the reaction [Acetylcysteine inhibits the reaction [Particulate Matter results in increased secretion of IL6 protein]]]; MYD88 protein affects the reaction [Polymyxin B promotes the reaction [Acetylcysteine inhibits the reaction [Particulate Matter results in increased secretion of TNF protein]]]
Acetylcysteine inhibits the reaction [Acrolein promotes the reaction [Lipopolysaccharides results in increased expression of MYD88 protein]]; Acetylcysteine inhibits the reaction [Acrolein results in increased expression of MYD88 protein]; Acetylcysteine inhibits the reaction [Lipopolysaccharides promotes the reaction [Acrolein results in increased expression of MYD88 protein]]

PMID:28495615 PMID:28555929 PMID:36055550 PMID:37369159

NCBI chr 8:119,074,439...119,078,508
Ensembl chr 8:119,074,437...119,079,415

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myosin heavy chain 3

multiple interactions

Acetylcysteine inhibits the reaction [Indican results in decreased expression of MYH3 protein]

NCBI chr10:51,770,177...51,793,994
Ensembl chr10:51,770,177...51,793,992

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myogenin

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of MYOG mRNA
Acetylcysteine inhibits the reaction [Indican results in decreased expression of MYOG protein]

PMID:22129741 PMID:29380555

NCBI chr13:45,745,455...45,748,044
Ensembl chr13:45,745,436...45,748,039

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Nanog homeobox

multiple interactions

Acetylcysteine inhibits the reaction [Particulate Matter results in decreased expression of NANOG protein]

NCBI chr 4:155,943,737...155,951,116
Ensembl chr 4:155,943,737...155,951,116

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nibrin

multiple interactions

Acetylcysteine inhibits the reaction [Doxorubicin promotes the reaction [ATM protein results in increased phosphorylation of NBN protein]]

NCBI chr 5:29,459,574...29,494,152
Ensembl chr 5:29,459,457...29,494,150

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neural cell adhesion molecule 2

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of NCAM2 mRNA

NCBI chr11:20,104,974...20,592,168
Ensembl chr11:20,104,925...20,591,984

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neutrophil cytosolic factor 1

decreases expression
multiple interactions

Acetylcysteine results in decreased expression of NCF1 protein
Acetylcysteine inhibits the reaction [Aldrin results in increased expression of NCF1 mRNA]; Acetylcysteine inhibits the reaction [alpha-hexachlorocyclohexane results in increased expression of NCF1 mRNA]; Acetylcysteine inhibits the reaction [Dichlorodiphenyl Dichloroethylene results in increased expression of NCF1 mRNA]; Acetylcysteine inhibits the reaction [Endosulfan results in increased expression of NCF1 mRNA]
Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of NCF1 protein]

PMID:21195169 PMID:28273962 PMID:29087013

NCBI chr12:22,485,382...22,494,647
Ensembl chr12:22,485,451...22,494,646

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neutrophil cytosolic factor 2

decreases expression
multiple interactions

Acetylcysteine results in decreased expression of NCF2 protein
Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of NCF2 protein]

NCBI chr13:64,955,622...64,986,144
Ensembl chr13:64,955,503...64,986,277

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neutrophil cytosolic factor 4

multiple interactions
decreases expression

Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of NCF4 protein]
Acetylcysteine results in decreased expression of NCF4 protein

NCBI chr 7:109,825,420...109,843,389
Ensembl chr 7:109,826,020...109,843,389

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nuclear receptor coactivator 4

multiple interactions

Acetylcysteine inhibits the reaction [di-n-propyldithiocarbamate results in increased expression of NCOA4 protein]

NCBI chr16:7,389,222...7,409,564
Ensembl chr16:7,366,542...7,409,641
Ensembl chr16:7,366,542...7,409,641

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NADH:ubiquinone oxidoreductase subunit B6

multiple interactions
increases expression

Acetylcysteine inhibits the reaction [Galactosamine results in decreased expression of NDUFB6 mRNA]
Acetylcysteine results in increased expression of NDUFB6 protein

NCBI chr 5:55,400,543...55,410,110
Ensembl chr 5:55,400,543...55,410,181

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NADH:ubiquinone oxidoreductase core subunit S7

increases expression

Acetylcysteine results in increased expression of NDUFS7 protein

NCBI chr 7:9,452,556...9,460,135
Ensembl chr 7:9,450,392...9,460,195

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neural precursor cell expressed, developmentally down-regulated 9

decreases expression

Acetylcysteine results in decreased expression of NEDD9 mRNA

NCBI chr17:23,289,793...23,468,026
Ensembl chr17:23,282,326...23,468,019

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neurofilament heavy chain

multiple interactions

Acetylcysteine inhibits the reaction [tributyltin results in decreased expression of NEFH protein]

NCBI chr14:79,830,362...79,840,347
Ensembl chr14:79,830,362...79,840,351

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neurofilament light chain

multiple interactions

Acetylcysteine inhibits the reaction [Rotenone results in decreased expression of NEFL mRNA]

NCBI chr15:42,301,920...42,305,793
Ensembl chr15:42,301,916...42,305,793

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NIMA-related kinase 4

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of NEK4 mRNA

NCBI chr16:6,144,900...6,185,376
Ensembl chr16:6,144,959...6,188,932

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nuclear factor of activated T-cells 1

multiple interactions

Acetylcysteine affects the reaction [NFE2L2 protein affects the reaction [sodium arsenite affects the expression of NFATC1 protein]]; Acetylcysteine affects the reaction [sodium arsenite affects the expression of NFATC1 protein]

NCBI chr18:74,046,422...74,156,041
Ensembl chr18:74,046,904...74,156,028

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nuclear factor of activated T-cells 3

multiple interactions

Acetylcysteine inhibits the reaction [Arsenic affects the localization of NFATC3 protein]

NCBI chr19:33,960,643...34,035,150
Ensembl chr19:33,960,852...34,035,150

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nuclear factor, erythroid 2

multiple interactions

Acetylcysteine inhibits the reaction [Aclarubicin results in increased expression of NFE2 mRNA]; Acetylcysteine inhibits the reaction [Butyric Acid results in increased expression of NFE2 mRNA]

NCBI chr 7:134,382,758...134,395,364
Ensembl chr 7:134,382,761...134,390,108

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NFE2 like bZIP transcription factor 2

multiple interactions
decreases expression
increases expression
affects localization

[6-formylindolo(3,2-b)carbazole co-treated with Acetylcysteine] results in decreased expression of NFE2L2 mRNA; [Acetylcysteine co-treated with Particulate Matter] results in decreased expression of NFE2L2 mRNA; Acetylcysteine affects the reaction [[NFE2L2 protein affects the susceptibility to sodium arsenite] affects the reaction [[CSF1R protein co-treated with TNFSF11 protein] affects the expression of ATP6V0D2 mRNA]]; Acetylcysteine affects the reaction [[NFE2L2 protein affects the susceptibility to sodium arsenite] affects the reaction [[CSF1R protein co-treated with TNFSF11 protein] affects the expression of CTSK mRNA]]; Acetylcysteine affects the reaction [NFE2L2 protein affects the reaction [sodium arsenite affects the expression of NFATC1 protein]]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in decreased expression of NFE2L2 protein]; Acetylcysteine inhibits the reaction [Copper Sulfate results in increased expression of NFE2L2 mRNA]; Acetylcysteine inhibits the reaction [Copper Sulfate results in increased expression of NFE2L2 protein]; Acetylcysteine inhibits the reaction [Doxorubicin results in decreased expression of NFE2L2 mRNA]; Acetylcysteine inhibits the reaction [Doxorubicin results in decreased expression of NFE2L2 protein]; Acetylcysteine inhibits the reaction [Hypochlorous Acid results in increased expression of NFE2L2 mRNA]; Acetylcysteine inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in decreased expression of NFE2L2 protein]; Acetylcysteine inhibits the reaction [Melatonin inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of NFE2L2 mRNA]]; Acetylcysteine inhibits the reaction [Melatonin inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of NFE2L2 protein]]; Acetylcysteine inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of NFE2L2 protein]; Acetylcysteine inhibits the reaction [Particulate Matter analog affects the localization of NFE2L2 protein]; Acetylcysteine inhibits the reaction [Vehicle Emissions analog affects the localization of NFE2L2 protein]
Acetylcysteine results in decreased expression of NFE2L2 mRNA
Acetylcysteine results in increased expression of NFE2L2 mRNA; Acetylcysteine results in increased expression of NFE2L2 protein
Acetylcysteine affects the localization of NFE2L2 protein
Acetylcysteine affects the reaction [Chlorpyrifos affects the expression of NFE2L2 protein]; Acetylcysteine inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased activity of NFE2L2 protein]; Acetylcysteine inhibits the reaction [3-O-caffeoyl-1-methylquinic acid affects the localization of NFE2L2 protein]; Acetylcysteine inhibits the reaction [4-(methylthio)-3-butenyl isothiocyanate results in increased expression of NFE2L2 protein]; Acetylcysteine inhibits the reaction [[Sulfasalazine results in increased abundance of Reactive Oxygen Species] which results in increased expression of and results in increased localization of NFE2L2 protein]; Acetylcysteine inhibits the reaction [Ammonium Chloride results in increased activity of NFE2L2 protein]; Acetylcysteine inhibits the reaction [Antimycin A results in increased expression of NFE2L2 mRNA]; Acetylcysteine inhibits the reaction [Arsenic Trioxide affects the localization of NFE2L2 protein]; Acetylcysteine inhibits the reaction [bisphenol A results in increased expression of NFE2L2 protein]; Acetylcysteine inhibits the reaction [cadmium acetate results in increased expression of NFE2L2 protein]; Acetylcysteine inhibits the reaction [Capsaicin results in increased localization of NFE2L2 protein]; Acetylcysteine inhibits the reaction [cobaltous chloride results in increased expression of NFE2L2 protein]; Acetylcysteine inhibits the reaction [diallyl trisulfide affects the localization of NFE2L2 protein]; Acetylcysteine inhibits the reaction [Dichlorodiphenyl Dichloroethylene results in decreased expression of NFE2L2 mRNA]; Acetylcysteine inhibits the reaction [Dichlorodiphenyl Dichloroethylene results in decreased expression of NFE2L2 protein]; Acetylcysteine inhibits the reaction [dimethoxyethyl phthalate results in decreased expression of NFE2L2 protein]; Acetylcysteine inhibits the reaction [Dinitrochlorobenzene results in increased expression of NFE2L2 protein]; Acetylcysteine inhibits the reaction [Docosahexaenoic Acids affects the localization of NFE2L2 protein]; Acetylcysteine inhibits the reaction [Docosahexaenoic Acids promotes the reaction [NFE2L2 protein binds to HMOX1 enhancer]]; Acetylcysteine inhibits the reaction [Docosahexaenoic Acids results in increased expression of and affects the localization of NFE2L2 protein]; Acetylcysteine inhibits the reaction [hydroquinone results in increased activity of NFE2L2 promoter]; Acetylcysteine inhibits the reaction [hydroquinone results in increased expression of NFE2L2 protein]; Acetylcysteine inhibits the reaction [Hypochlorous Acid results in increased expression of NFE2L2 mRNA]; Acetylcysteine inhibits the reaction [Indomethacin inhibits the reaction [KEAP1 protein binds to NFE2L2 protein]]; Acetylcysteine inhibits the reaction [Indomethacin results in increased localization of NFE2L2 protein]; Acetylcysteine inhibits the reaction [Mercuric Chloride promotes the reaction [Lipopolysaccharides results in increased expression of NFE2L2 protein]]; Acetylcysteine inhibits the reaction [Mercuric Chloride results in increased expression of NFE2L2 protein]; Acetylcysteine inhibits the reaction [methylmercuric chloride results in increased expression of NFE2L2 protein]; Acetylcysteine inhibits the reaction [NFE2L2 protein affects the reaction [Silver results in increased abundance of Reactive Oxygen Species]]; Acetylcysteine inhibits the reaction [NFE2L2 protein affects the susceptibility to Silver]; Acetylcysteine inhibits the reaction [nickel chloride results in increased expression of NFE2L2 protein]; Acetylcysteine inhibits the reaction [Paraquat results in decreased expression of NFE2L2 protein]; Acetylcysteine inhibits the reaction [Polychlorinated Biphenyls analog results in increased expression of NFE2L2 protein]; Acetylcysteine inhibits the reaction [pterostilbene results in increased phosphorylation of NFE2L2 protein]; Acetylcysteine inhibits the reaction [Silver analog results in increased expression of NFE2L2 mRNA]; Acetylcysteine inhibits the reaction [sodium arsenite affects the localization of NFE2L2 protein]; Acetylcysteine inhibits the reaction [sodium arsenite promotes the reaction [NFE2L2 protein binds to HMOX1 enhancer]]; Acetylcysteine inhibits the reaction [sodium arsenite promotes the reaction [NFE2L2 protein binds to HSF1 promoter]]; Acetylcysteine inhibits the reaction [sodium arsenite promotes the reaction [NFE2L2 protein binds to NQO1 promoter]]; Acetylcysteine inhibits the reaction [sulforaphane affects the localization of NFE2L2 protein]; Acetylcysteine inhibits the reaction [sulforaphane results in increased expression of NFE2L2 protein]; Acetylcysteine inhibits the reaction [sulforaphane results in increased phosphorylation of and results in increased activity of NFE2L2 protein]; Acetylcysteine inhibits the reaction [thymoquinone affects the localization of and results in increased activity of NFE2L2 protein]; Acetylcysteine inhibits the reaction [Tobacco Smoke Pollution analog results in increased expression of NFE2L2 protein]
[Acetylcysteine affects the abundance of Reactive Oxygen Species] inhibits the reaction [manganese chloride promotes the reaction [NFE2L2 protein binds to HMOX1 promoter]]; [Acetylcysteine affects the abundance of Reactive Oxygen Species] inhibits the reaction [manganese chloride results in increased activity of NFE2L2 protein]; [Acetylcysteine affects the abundance of Reactive Oxygen Species] inhibits the reaction [manganese chloride results in increased expression of NFE2L2 protein]; [Particulate Matter co-treated with Acetylcysteine] results in increased expression of NFE2L2 protein; Acetylcysteine affects the reaction [yttrium chloride affects the expression of NFE2L2 protein]; Acetylcysteine inhibits the reaction [[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of NFE2L2 mRNA]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of and affects the localization of NFE2L2 protein]; Acetylcysteine inhibits the reaction [aureusidin affects the localization of NFE2L2 protein]; Acetylcysteine inhibits the reaction [decamethrin affects the localization of NFE2L2 protein]; Acetylcysteine inhibits the reaction [decamethrin results in increased activity of NFE2L2 protein]; Acetylcysteine inhibits the reaction [decamethrin results in increased expression of NFE2L2 protein]; Acetylcysteine inhibits the reaction [Doxorubicin results in decreased expression of NFE2L2 protein]; Acetylcysteine inhibits the reaction [ferrous sulfate affects the localization of NFE2L2 protein]; Acetylcysteine inhibits the reaction [Glyphosate results in decreased expression of NFE2L2 mRNA]; Acetylcysteine inhibits the reaction [methylmercuric chloride results in increased expression of NFE2L2 protein]; Acetylcysteine inhibits the reaction [Particulate Matter results in decreased expression of NFE2L2 protein]; Acetylcysteine inhibits the reaction [Sodium Fluoride affects the localization of NFE2L2 protein]; Acetylcysteine inhibits the reaction [Sodium Fluoride results in decreased expression of NFE2L2 mRNA]; Acetylcysteine inhibits the reaction [tributyltin results in increased expression of NFE2L2 protein]; Acetylcysteine inhibits the reaction [triptolide affects the expression of NFE2L2 protein]; Acetylcysteine promotes the reaction [Acrylamide results in increased expression of and affects the localization of NFE2L2 protein]; Acetylcysteine promotes the reaction [Hydrogen Peroxide affects the localization of NFE2L2 protein]; Sodium Fluoride promotes the reaction [Acetylcysteine affects the localization of NFE2L2 protein]

PMID:11909699 PMID:15322212 PMID:16631525 PMID:16806455 PMID:16959797 More...

NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737

G

nuclear factor, interleukin 3 regulated

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of NFIL3 mRNA

NCBI chr17:12,280,499...12,295,728
Ensembl chr17:12,280,484...12,295,858

G

nuclear factor kappa B subunit 1

multiple interactions

Acetylcysteine inhibits the reaction [Drugs, Chinese Herbal inhibits the reaction [lipopolysaccharide, E coli O55-B5 affects the localization of NFKB1 protein]]
Acetylcysteine inhibits the reaction [7-ketocholesterol results in increased expression of NFKB1 protein]; Acetylcysteine inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of NFKB1 mRNA]; Acetylcysteine inhibits the reaction [Lipopolysaccharides affects the localization of NFKB1 protein]; Acetylcysteine inhibits the reaction [Palmitic Acid results in increased expression of NFKB1 mRNA]
Acetylcysteine inhibits the reaction [2'-(4-chlorophenyl)-3-(4-chlorophenylidene)-5,10-dimethyl-12-methylene-decahydro-1,2-(1',3'-dioxocyclopenta(c))azuleno(4,5-b)furan-4,11-dione results in decreased expression of NFKB1 protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in decreased activity of NFKB1 protein]; Acetylcysteine inhibits the reaction [NCX 4040 results in decreased activity of NFKB1 protein]; Acetylcysteine inhibits the reaction [Norepinephrine affects the localization of NFKB1 protein]; Acetylcysteine inhibits the reaction [phosphoaspirin results in decreased activity of NFKB1 protein]; Acetylcysteine inhibits the reaction [Sulindac analog results in decreased activity of NFKB1 protein]; Acetylcysteine inhibits the reaction [tert-Butylhydroperoxide results in increased expression of NFKB1 protein]; Acetylcysteine inhibits the reaction [titanium dioxide results in increased expression of NFKB1 protein]; Acetylcysteine inhibits the reaction [Zinc deficiency affects the localization of NFKB1 protein]

PMID:11970852 PMID:18922898 PMID:19642688 PMID:21600978 PMID:21741372 More...

NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404

G

nuclear factor kappa B subunit 2

multiple interactions

Acetylcysteine inhibits the reaction [Drugs, Chinese Herbal inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of NFKB2 protein]]

NCBI chr 1:245,164,586...245,173,225
Ensembl chr 1:245,165,950...245,173,213

G

NFKB inhibitor alpha

multiple interactions
affects expression
decreases degradation

Acetylcysteine inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in decreased expression of NFKBIA protein]; Acetylcysteine inhibits the reaction [Platelet Activating Factor results in increased degradation of NFKBIA protein]
Acetylcysteine inhibits the reaction [7-ketocholesterol results in increased expression of NFKBIA protein]; Acetylcysteine inhibits the reaction [[Diethylnitrosamine co-treated with 2-Acetylaminofluorene] results in increased phosphorylation of NFKBIA protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased degradation of NFKBIA protein]; Acetylcysteine inhibits the reaction [ferrous sulfate results in increased phosphorylation of NFKBIA protein]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased phosphorylation of NFKBIA protein]
Acetylcysteine affects the expression of NFKBIA protein
Acetylcysteine results in decreased degradation of NFKBIA protein
Acetylcysteine inhibits the reaction [1,2,5,8-tetrahydroxy anthraquinone results in decreased phosphorylation of NFKBIA protein]; Acetylcysteine inhibits the reaction [1,2,5,8-tetrahydroxy anthraquinone results in increased expression of NFKBIA protein]; Acetylcysteine inhibits the reaction [2'-(4-chlorophenyl)-3-(4-chlorophenylidene)-5,10-dimethyl-12-methylene-decahydro-1,2-(1',3'-dioxocyclopenta(c))azuleno(4,5-b)furan-4,11-dione results in increased expression of NFKBIA protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of NFKBIA protein]; Acetylcysteine inhibits the reaction [cryptotanshinone results in increased degradation of and results in increased phosphorylation of NFKBIA protein]; Acetylcysteine inhibits the reaction [piperlongumine analog inhibits the reaction [TNF protein results in increased degradation of NFKBIA protein]]; NFKBIA protein affects the reaction [Acetylcysteine results in decreased susceptibility to hydroxyethyl methacrylate]

PMID:10636889 PMID:10921504 PMID:15949477 PMID:16214328 PMID:18404532 More...

NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941

G

NFKB inhibitor beta

multiple interactions

Acetylcysteine inhibits the reaction [oenothein B results in decreased phosphorylation of NFKBIB protein]; Acetylcysteine inhibits the reaction [Tosylphenylalanyl Chloromethyl Ketone results in decreased phosphorylation of NFKBIB protein]

PMID:10381628 PMID:30452899

NCBI chr 1:84,046,292...84,053,862
Ensembl chr 1:84,046,295...84,053,862

G

nerve growth factor

multiple interactions

Acetylcysteine inhibits the reaction [NGF protein results in increased localization of and results in increased activity of PRKCE protein]; Acetylcysteine inhibits the reaction [NGF protein results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [NGF protein results in increased phosphorylation of MAPK3 protein]
Acetylcysteine inhibits the reaction [Buthionine Sulfoximine results in increased expression of NGF mRNA]

PMID:16603213 PMID:18375950 PMID:23472850

NCBI chr 2:189,901,058...189,954,452
Ensembl chr 2:189,901,058...189,954,452

G

neuroligin 3

multiple interactions

Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in decreased expression of NLGN3 mRNA]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased methylation of NLGN3 promoter]; Acetylcysteine inhibits the reaction [Particulate Matter results in decreased expression of NLGN3 mRNA]; Acetylcysteine inhibits the reaction [Particulate Matter results in decreased expression of NLGN3 protein]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased methylation of NLGN3 promoter]

NCBI chr X:66,427,926...66,457,378
Ensembl chr X:66,429,458...66,451,876

G

NLR family, pyrin domain containing 3

multiple interactions
increases expression

Acetylcysteine inhibits the reaction [2,3,5-trichloro-6-phenyl-(1,4)benzoquinone results in increased expression of NLRP3 protein]; Acetylcysteine inhibits the reaction [[Acrolein co-treated with Lipopolysaccharides] results in increased expression of NLRP3 protein]; Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of NLRP3 mRNA]; Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of NLRP3 protein]; Acetylcysteine inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of NLRP3 protein]; Acetylcysteine inhibits the reaction [[Peanut Oil results in increased abundance of Particulate Matter] which results in increased expression of NLRP3 mRNA]; Acetylcysteine inhibits the reaction [[Peanut Oil results in increased abundance of Particulate Matter] which results in increased expression of NLRP3 protein]; Acetylcysteine inhibits the reaction [Acrolein results in increased expression of NLRP3 protein]; Acetylcysteine inhibits the reaction [APP protein results in increased expression of NLRP3 protein]; Acetylcysteine inhibits the reaction [Chlorpyrifos results in increased expression of NLRP3 protein]; Acetylcysteine inhibits the reaction [hydroquinone results in increased expression of NLRP3 protein]; Acetylcysteine inhibits the reaction [Imatinib Mesylate results in increased expression of NLRP3 protein]; Acetylcysteine inhibits the reaction [Lipopolysaccharides promotes the reaction [Acrolein results in increased expression of NLRP3 protein]]; Acetylcysteine inhibits the reaction [Lipopolysaccharides results in increased expression of NLRP3 protein]; Acetylcysteine inhibits the reaction [saikosaponin D results in increased expression of NLRP3 protein]; Acetylcysteine inhibits the reaction [tetrachlorobenzoquinone results in increased expression of and results in decreased ubiquitination of NLRP3 protein]; Quercetin promotes the reaction [Acetylcysteine inhibits the reaction [Lipopolysaccharides results in increased expression of NLRP3 protein]]
Acetylcysteine inhibits the reaction [cadmium acetate results in increased expression of NLRP3 protein]; Acetylcysteine inhibits the reaction [Palmitic Acid results in increased expression of NLRP3 mRNA]
Acetylcysteine inhibits the reaction [Aluminum Chloride results in increased expression of NLRP3 mRNA]; Acetylcysteine inhibits the reaction [Aluminum Chloride results in increased expression of NLRP3 protein]; Acetylcysteine inhibits the reaction [Lipopolysaccharides results in increased expression of NLRP3 protein]; Acetylcysteine inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of NLRP3 protein]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of NLRP3 protein]; Acetylcysteine inhibits the reaction [Rotenone results in increased expression of NLRP3 protein]; Acetylcysteine inhibits the reaction [Tobacco Smoke Pollution analog results in increased expression of NLRP3 protein]; Acetylcysteine inhibits the reaction [Vehicle Emissions results in increased expression of NLRP3 protein]
Acetylcysteine results in increased expression of NLRP3 mRNA; Acetylcysteine results in increased expression of NLRP3 protein

PMID:24885895 PMID:26086368 PMID:26435000 PMID:26901245 PMID:28004443 More...

NCBI chr10:44,326,770...44,353,814
Ensembl chr10:44,328,566...44,352,811

G

nitric oxide synthase 2

multiple interactions

Acetylcysteine inhibits the reaction [2'-(4-chlorophenyl)-3-(4-chlorophenylidene)-5,10-dimethyl-12-methylene-decahydro-1,2-(1',3'-dioxocyclopenta(c))azuleno(4,5-b)furan-4,11-dione results in increased expression of NOS2 protein]; Acetylcysteine inhibits the reaction [[ferric ammonium citrate co-treated with Buthionine Sulfoximine] results in increased expression of NOS2 mRNA]; Acetylcysteine inhibits the reaction [Asbestos, Crocidolite results in increased expression of NOS2 mRNA]; Acetylcysteine inhibits the reaction [nickel chloride results in decreased expression of NOS2 mRNA]
Acetylcysteine inhibits the reaction [Drugs, Chinese Herbal inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of NOS2 protein]]; Acetylcysteine inhibits the reaction [Humic Substances results in increased expression of NOS2 mRNA]; Acetylcysteine inhibits the reaction [Humic Substances results in increased expression of NOS2 protein]; Acetylcysteine inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of NOS2 mRNA]; Acetylcysteine inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of NOS2 protein]; Acetylcysteine inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; Acetylcysteine inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]; Acetylcysteine inhibits the reaction [mancozeb results in increased expression of NOS2 mRNA]; Acetylcysteine inhibits the reaction [Nicotine results in increased expression of NOS2 mRNA]; Acetylcysteine inhibits the reaction [orazipone inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]]; Acetylcysteine inhibits the reaction [Paraquat results in increased expression of NOS2 mRNA]; Acetylcysteine inhibits the reaction [Paraquat results in increased expression of NOS2 protein]; Acetylcysteine inhibits the reaction [titanium dioxide results in increased expression of NOS2 protein]
Acetylcysteine inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of NOS2 mRNA]; Acetylcysteine inhibits the reaction [cobaltous chloride results in increased expression of NOS2 protein]; Acetylcysteine inhibits the reaction [cypermethrin results in increased expression of NOS2 mRNA]; Acetylcysteine inhibits the reaction [diethyl maleate inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]]; Acetylcysteine inhibits the reaction [Palmitic Acid results in increased expression of NOS2 mRNA]; Acetylcysteine inhibits the reaction [Paraquat results in increased expression of NOS2 mRNA]; Acetylcysteine inhibits the reaction [TNF protein results in increased expression of NOS2 protein]; Acetylcysteine inhibits the reaction [Triglycerides results in decreased expression of NOS2 mRNA]; Acetylcysteine inhibits the reaction [Triglycerides results in decreased expression of NOS2 protein]

PMID:7532384 PMID:9826428 PMID:9918918 PMID:16140881 PMID:18039960 More...

NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210

G

nitric oxide synthase 3

multiple interactions
increases expression

Acetylcysteine inhibits the reaction [Streptozocin results in decreased phosphorylation of NOS3 protein]; Acetylcysteine inhibits the reaction [Triglycerides results in decreased expression of NOS3 mRNA]; Acetylcysteine inhibits the reaction [Triglycerides results in decreased expression of NOS3 protein]; Allopurinol promotes the reaction [Acetylcysteine inhibits the reaction [Streptozocin results in decreased phosphorylation of NOS3 protein]]
Acetylcysteine inhibits the reaction [Aldrin results in increased expression of NOS3 mRNA]; Acetylcysteine inhibits the reaction [alpha-hexachlorocyclohexane results in increased expression of NOS3 mRNA]; Acetylcysteine inhibits the reaction [Dichlorodiphenyl Dichloroethylene results in increased expression of NOS3 mRNA]; Acetylcysteine inhibits the reaction [Endosulfan results in increased expression of NOS3 mRNA]; Acetylcysteine inhibits the reaction [Glycochenodeoxycholic Acid results in decreased expression of NOS3 mRNA]; Acetylcysteine inhibits the reaction [Glycochenodeoxycholic Acid results in decreased expression of NOS3 protein]; Acetylcysteine inhibits the reaction [Oxygen deficiency results in decreased expression of NOS3 protein]; Acetylcysteine inhibits the reaction [TNF results in decreased expression of NOS3 protein]
Acetylcysteine results in increased expression of NOS3 protein

PMID:16140881 PMID:17026986 PMID:17321519 PMID:19837105 PMID:21912612 More...

NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166

G

NADPH oxidase 1

multiple interactions

Acetylcysteine inhibits the reaction [Doxorubicin results in increased expression of NOX1 mRNA]

NCBI chr X:97,279,058...97,332,291
Ensembl chr X:97,279,056...97,302,236

G

NADPH oxidase 4

multiple interactions

Acetylcysteine inhibits the reaction [mancozeb results in increased expression of NOX4 mRNA]; Acetylcysteine inhibits the reaction [NOX4 protein promotes the reaction [[Lipopolysaccharides co-treated with IFNG1 protein] results in increased expression of AIF1 protein]]; Acetylcysteine inhibits the reaction [NOX4 protein promotes the reaction [[Lipopolysaccharides co-treated with IFNG1 protein] results in increased expression of CS protein]]; Acetylcysteine inhibits the reaction [NOX4 protein promotes the reaction [[Lipopolysaccharides co-treated with IFNG1 protein] results in increased expression of HK2 protein]]; Acetylcysteine inhibits the reaction [NOX4 protein promotes the reaction [[Lipopolysaccharides co-treated with IFNG1 protein] results in increased expression of IL1B protein]]; Acetylcysteine inhibits the reaction [NOX4 protein promotes the reaction [[Lipopolysaccharides co-treated with IFNG1 protein] results in increased expression of IL6 protein]]; Acetylcysteine inhibits the reaction [NOX4 protein promotes the reaction [[Lipopolysaccharides co-treated with IFNG1 protein] results in increased expression of PKM protein]]; Acetylcysteine inhibits the reaction [NOX4 protein promotes the reaction [[Lipopolysaccharides co-treated with IFNG1 protein] results in increased expression of TNF protein]]; Acetylcysteine inhibits the reaction [salubrinal results in increased expression of [Cisplatin results in increased expression of NOX4 protein]]
Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of NOX4 mRNA]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of NOX4 protein]; Acetylcysteine inhibits the reaction [TGFB1 protein results in increased expression of NOX4 mRNA]; Acetylcysteine inhibits the reaction [Vehicle Emissions results in increased expression of NOX4 mRNA]; Acetylcysteine inhibits the reaction [Vehicle Emissions results in increased expression of NOX4 protein]

PMID:21131394 PMID:21616140 PMID:24224404 PMID:30037311 PMID:36762617

NCBI chr 1:140,900,886...141,078,844
Ensembl chr 1:140,901,097...141,077,406

G

neuronal PAS domain protein 2

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of NPAS2 mRNA

NCBI chr 9:41,463,361...41,642,322
Ensembl chr 9:41,463,830...41,642,320

G

neuropeptide FF-amide peptide precursor

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of NPFF mRNA; Acetylcysteine inhibits the reaction [[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of NPFF mRNA]

NCBI chr 7:133,654,530...133,655,319

G

nucleophosmin 1

multiple interactions

Acetylcysteine inhibits the reaction [NPM1 protein mutant form results in increased susceptibility to arsenic trioxide]; Acetylcysteine inhibits the reaction [NPM1 protein mutant form results in increased susceptibility to Bortezomib]

NCBI chr10:17,741,512...17,751,626
Ensembl chr10:17,739,941...17,751,645

G

NAD(P)H quinone dehydrogenase 1

multiple interactions
increases expression

[Acetylcysteine inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]] which results in decreased expression of NQO1 mRNA; Acetylcysteine inhibits the reaction [2-tert-butylhydroquinone results in increased expression of NQO1 mRNA]; Acetylcysteine inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] which results in increased expression of NQO1 mRNA]; Acetylcysteine inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] which results in increased expression of NQO1 protein]; Acetylcysteine inhibits the reaction [Antimycin A results in increased expression of NQO1 mRNA]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of NQO1 protein]; Acetylcysteine inhibits the reaction [Aspirin analog results in increased activity of NQO1 protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of NQO1 mRNA]; Acetylcysteine inhibits the reaction [diallyl trisulfide results in increased expression of NQO1 protein]; Acetylcysteine inhibits the reaction [Dinitrochlorobenzene results in increased expression of NQO1 mRNA]; Acetylcysteine inhibits the reaction [Mercury results in increased expression of NQO1 mRNA]; Acetylcysteine inhibits the reaction [NQO1 protein results in increased susceptibility to 9,10-phenanthrenequinone]; Acetylcysteine inhibits the reaction [Particulate Matter analog results in increased expression of NQO1 mRNA]; Acetylcysteine inhibits the reaction [Particulate Matter analog results in increased expression of NQO1 protein]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of NQO1 mRNA]; Acetylcysteine inhibits the reaction [pterostilbene results in increased expression of NQO1 mRNA]; Acetylcysteine inhibits the reaction [sodium arsenite promotes the reaction [NFE2L2 protein binds to NQO1 promoter]]; Acetylcysteine inhibits the reaction [sulforaphane results in increased expression of NQO1 mRNA]; Acetylcysteine inhibits the reaction [tetrabromobisphenol A results in increased expression of NQO1 mRNA]; Acetylcysteine inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of NQO1 mRNA]; Acetylcysteine inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of NQO1 protein]; Acetylcysteine inhibits the reaction [Vehicle Emissions analog results in increased expression of NQO1 mRNA]; Acetylcysteine inhibits the reaction [Vehicle Emissions analog results in increased expression of NQO1 protein]; Acetylcysteine inhibits the reaction [Vehicle Emissions results in increased expression of NQO1 mRNA]; NQO1 protein promotes the reaction [Acetylcysteine results in decreased susceptibility to 9,10-phenanthrenequinone]
Acetylcysteine results in increased expression of NQO1 mRNA; Acetylcysteine results in increased expression of NQO1 protein
[Acetylcysteine co-treated with Sodium Fluoride] results in increased expression of NQO1 mRNA; Acetylcysteine inhibits the reaction [[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of NQO1 mRNA]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in decreased expression of NQO1 protein]; Acetylcysteine promotes the reaction [Sodium Fluoride results in increased expression of NQO1 protein]
[Acetylcysteine co-treated with chromium trioxide] inhibits the reaction [Tetrachlorodibenzodioxin results in increased activity of NQO1 protein]; Acetylcysteine inhibits the reaction [2',4'-dihydroxy-6'-methoxy-3',5'-dimethylchalcone results in increased expression of NQO1 mRNA]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in decreased expression of NQO1 mRNA]; Acetylcysteine inhibits the reaction [Cadmium Chloride promotes the reaction [Tetrachlorodibenzodioxin results in increased activity of NQO1 protein]]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased activity of NQO1 protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of NQO1 mRNA]; Acetylcysteine inhibits the reaction [Copper Sulfate results in increased expression of NQO1 mRNA]; Acetylcysteine inhibits the reaction [Copper Sulfate results in increased expression of NQO1 protein]; Acetylcysteine inhibits the reaction [Melatonin inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of NQO1 mRNA]]; Acetylcysteine inhibits the reaction [Melatonin inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of NQO1 protein]]; Acetylcysteine inhibits the reaction [sodium arsenite promotes the reaction [Tetrachlorodibenzodioxin results in increased activity of NQO1 protein]]; Acetylcysteine inhibits the reaction [sodium arsenite results in increased activity of NQO1 protein]; Acetylcysteine inhibits the reaction [sodium arsenite results in increased expression of NQO1 mRNA]; Acetylcysteine promotes the reaction [Benzo(a)pyrene results in increased expression of NQO1 protein]

PMID:12730081 PMID:15044633 PMID:16274885 PMID:16920990 PMID:19033392 More...

NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557

G

nuclear receptor subfamily 2, group E, member 3

multiple interactions

Acetylcysteine inhibits the reaction [Benzo(a)pyrene results in decreased expression of NR2E3 protein]

NCBI chr 8:60,365,581...60,373,383
Ensembl chr 8:60,366,124...60,373,163

G

nuclear receptor subfamily 3, group C, member 1

decreases expression
multiple interactions

Acetylcysteine results in decreased expression of NR3C1 mRNA
Acetylcysteine inhibits the reaction [anacetrapib results in increased expression of NR3C1 mRNA]; Acetylcysteine inhibits the reaction [dalcetrapib results in increased expression of NR3C1 mRNA]; Acetylcysteine inhibits the reaction [torcetrapib results in increased expression of NR3C1 mRNA]

PMID:16084531 PMID:25617244

NCBI chr18:31,271,681...31,393,320
Ensembl chr18:31,271,681...31,393,375

G

nuclear receptor subfamily 3, group C, member 2

multiple interactions

Acetylcysteine inhibits the reaction [anacetrapib results in increased expression of NR3C2 mRNA]; Acetylcysteine inhibits the reaction [dalcetrapib results in increased expression of NR3C2 mRNA]; Acetylcysteine inhibits the reaction [torcetrapib results in increased expression of NR3C2 mRNA]

NCBI chr19:30,715,634...31,059,885
Ensembl chr19:30,715,648...31,059,885

G

nuclear respiratory factor 1

multiple interactions

Acetylcysteine inhibits the reaction [Atorvastatin results in increased expression of NRF1 mRNA]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in decreased expression of NRF1 mRNA]; Acetylcysteine inhibits the reaction [Monocrotophos results in decreased expression of NRF1 mRNA]; Acetylcysteine inhibits the reaction [sodium bisulfite results in decreased expression of NRF1 mRNA]

PMID:21775390 PMID:26980303 PMID:35403558 PMID:36493885

NCBI chr 4:58,664,932...58,772,328
Ensembl chr 4:58,664,957...58,825,328

G

neurexin 1

multiple interactions

Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in decreased expression of NRXN1 mRNA]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased methylation of NRXN1 promoter]; Acetylcysteine inhibits the reaction [Particulate Matter results in decreased expression of NRXN1 mRNA]; Acetylcysteine inhibits the reaction [Particulate Matter results in decreased expression of NRXN1 protein]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased methylation of NRXN1 promoter]

NCBI chr 6:3,177,788...4,323,848
Ensembl chr 6:3,177,897...4,322,710

G

neurotrophin 3

multiple interactions

Acetylcysteine inhibits the reaction [Cadmium Chloride results in decreased expression of NTF3 protein]

NCBI chr 4:158,914,984...158,984,453
Ensembl chr 4:158,914,957...158,984,596

G

nth-like DNA glycosylase 1

multiple interactions

Acetylcysteine inhibits the reaction [Tobacco Smoke Pollution results in increased expression of NTHL1 mRNA]

NCBI chr10:13,655,791...13,661,958
Ensembl chr10:13,655,785...13,661,957

G

neurotrophic receptor tyrosine kinase 1

multiple interactions

Acetylcysteine inhibits the reaction [Acetaminophen results in increased phosphorylation of and results in increased activity of NTRK1 protein]; Acetylcysteine inhibits the reaction [Buthionine Sulfoximine results in increased phosphorylation of and results in increased activity of NTRK1 protein]

NCBI chr 2:173,236,961...173,253,806
Ensembl chr 2:173,236,963...173,253,770

G

neurotrophic receptor tyrosine kinase 2

multiple interactions

Acetylcysteine inhibits the reaction [Streptozocin results in decreased phosphorylation of NTRK2 protein]

NCBI chr17:5,558,992...5,870,299
Ensembl chr17:5,559,043...5,869,136

G

NUAK family kinase 2

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of NUAK2 mRNA

NCBI chr13:43,753,454...43,770,604
Ensembl chr13:43,753,832...43,770,604

G

nuclear protein 1, transcriptional regulator

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of NUPR1 mRNA
Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of NUPR1 mRNA]

PMID:22129741 PMID:31319114

NCBI chr 1:181,213,292...181,215,327
Ensembl chr 1:181,213,368...181,215,281

G

occludin

multiple interactions

Acetylcysteine inhibits the reaction [Arsenic Trioxide results in decreased expression of OCLN mRNA]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in decreased expression of OCLN protein]; Acetylcysteine inhibits the reaction [Particulate Matter results in decreased expression of OCLN protein]
Acetylcysteine inhibits the reaction [Glyphosate results in decreased expression of OCLN protein]
Acetylcysteine inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of OCLN mRNA]; Acetylcysteine inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of OCLN protein]; Acetylcysteine inhibits the reaction [bisphenol A results in decreased expression of OCLN mRNA]

PMID:29235125 PMID:32683294 PMID:32687961 PMID:33485121 PMID:34906888 More...

NCBI chr 2:31,657,217...31,707,466
Ensembl chr 2:31,657,220...31,764,150

G

O-GlcNAcase

decreases expression

Acetylcysteine results in decreased expression of OGA mRNA

NCBI chr 1:244,598,285...244,633,835
Ensembl chr 1:244,598,292...244,634,359

G

oxidized low density lipoprotein receptor 1

multiple interactions

Acetylcysteine inhibits the reaction [Doxorubicin results in increased expression of OLR1 mRNA]; Acetylcysteine inhibits the reaction [Doxorubicin results in increased expression of OLR1 protein]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased expression of OLR1 mRNA]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased expression of OLR1 protein]
Acetylcysteine inhibits the reaction [sodium arsenite results in increased expression of OLR1 protein]

PMID:16055083 PMID:24145059

NCBI chr 4:162,926,436...162,949,057
Ensembl chr 4:162,926,439...162,948,523

G

olfactory receptor 1093

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of OLR1093 mRNA

NCBI chr 7:12,575,398...12,576,354
Ensembl chr 7:12,574,956...12,587,973

G

olfactory receptor 1451

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of OLR1451 mRNA

NCBI chr10:43,429,140...43,430,069
Ensembl chr10:43,424,036...43,432,210

G

olfactory receptor 1481

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of OLR1481 mRNA

NCBI chr10:58,237,886...58,238,830
Ensembl chr10:58,235,688...58,239,281

G

olfactory receptor 59

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of OLR59 mRNA

NCBI chr 1:157,193,051...157,227,707
Ensembl chr 1:157,193,080...157,211,179

G

oligodendrocyte-myelin glycoprotein

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of OMG mRNA

NCBI chr10:64,461,350...64,464,084
Ensembl chr10:64,461,350...64,464,084

G

OPA1, mitochondrial dynamin like GTPase

multiple interactions

Acetylcysteine inhibits the reaction [15-deoxyprostaglandin J2 results in increased expression of OPA1 protein alternative form]; Acetylcysteine inhibits the reaction [15-deoxyprostaglandin J2 results in increased ubiquitination of OPA1 protein]; Acetylcysteine inhibits the reaction [Doxorubicin results in decreased expression of OPA1 protein]
Acetylcysteine inhibits the reaction [Polystyrenes analog results in decreased expression of OPA1 protein]

PMID:20678484 PMID:37084995 PMID:37499777

NCBI chr11:71,108,100...71,185,170
Ensembl chr11:71,109,873...71,185,109

G

olfactory receptor family 10 subfamily AL member 5B

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of OR10AL5B mRNA

NCBI chr20:798,038...810,925
Ensembl chr20:734,965...811,125

G

olfactory receptor family 1 subfamily F member 30

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of OR1F30 mRNA

NCBI chr10:12,483,032...12,483,973
Ensembl chr10:12,481,906...12,484,513

G

olfactory receptor family 2 subfamily AK member 5F

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of OR2AK6 mRNA

NCBI chr10:43,269,046...43,269,960
Ensembl chr10:43,289,142...43,290,062

G

olfactory receptor family 2 subfamily T member 48E

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of OR2T48E mRNA

NCBI chr10:42,690,368...42,691,297
Ensembl chr10:42,689,609...42,701,405

G

olfactory receptor family 4 subfamily A member 77D

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of OR4A77D mRNA

NCBI chr 3:75,796,815...75,797,765
Ensembl chr 3:75,796,364...75,801,803

G

olfactory receptor family 4 subfamily C member 105B

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of OR4C105B mRNA

NCBI chr 3:74,458,280...74,459,209
Ensembl chr 3:74,455,596...74,467,433

G

olfactory receptor family 4 subfamily F member 4B

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of OR4F4B mRNA

NCBI chr 3:98,058,061...98,061,955

G

olfactory receptor family 4 subfamily P member 20B

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of OR4P20B mRNA

NCBI chr 3:74,022,169...74,023,089
Ensembl chr 3:74,022,169...74,023,089

G

olfactory receptor family 4 subfamily S member 2

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of OR4S2 mRNA

NCBI chr 3:74,377,492...74,378,427
Ensembl chr 3:74,375,165...74,381,097

G

olfactory receptor family 51 subfamily I member 2

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of OR51I2 mRNA

NCBI chr 1:158,513,673...158,514,611
Ensembl chr 1:158,513,673...158,514,611

G

olfactory receptor family 5 subfamily AS member 1

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of OR5AS1 mRNA

NCBI chr 3:72,324,043...72,324,981
Ensembl chr 3:72,323,706...72,326,585

G

olfactory receptor family 6 subfamily D member 13C

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of OR6D13C mRNA

NCBI chr 4:149,752,294...149,753,277
Ensembl chr 4:149,750,101...149,754,458

G

olfactory receptor family 8 subfamily G member 2C

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of OR8G2C mRNA

NCBI chr 8:40,226,318...40,227,241
Ensembl chr 8:40,223,812...40,227,610

G

ORMDL sphingolipid biosynthesis regulator 3

multiple interactions

Acetylcysteine inhibits the reaction [Benomyl results in increased expression of ORMDL3 protein]

NCBI chr10:83,590,052...83,596,035
Ensembl chr10:83,590,071...83,598,620

G

oxidative stress responsive serine-rich 1

multiple interactions

Acetylcysteine inhibits the reaction [elesclomol results in increased expression of OSER1 mRNA]

NCBI chr 3:152,066,975...152,085,180
Ensembl chr 3:152,066,975...152,085,149

G

oxidative stress induced growth inhibitor 1

multiple interactions

Acetylcysteine inhibits the reaction [Docosahexaenoic Acids results in increased expression of OSGIN1 protein]

NCBI chr19:47,471,750...47,500,517
Ensembl chr19:47,492,171...47,500,516

G

otoancorin

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of OTOA mRNA

NCBI chr 1:175,642,978...175,710,528
Ensembl chr 1:175,642,975...175,710,435

G

purinergic receptor P2X 2

multiple interactions

Acetylcysteine inhibits the reaction [Hydrogen Peroxide promotes the reaction [Adenosine Triphosphate results in increased activity of P2RX2 protein]]; Acetylcysteine inhibits the reaction [Rotenone promotes the reaction [Adenosine Triphosphate results in increased activity of P2RX2 protein]]

NCBI chr12:46,338,979...46,342,891
Ensembl chr12:46,339,549...46,342,891

G

purinergic receptor P2X 5

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of P2RX5 mRNA

NCBI chr10:57,777,737...57,789,426
Ensembl chr10:57,777,819...57,789,423

G

p21 (RAC1) activated kinase 6

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of PAK6 mRNA

NCBI chr 3:105,638,248...105,674,399
Ensembl chr 3:105,638,653...105,672,975

G

progestin and adipoQ receptor family member 9

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of PAQR9 mRNA

NCBI chr 8:96,114,249...96,116,546

G

Parkinsonism associated deglycase

multiple interactions

Acetylcysteine inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased oxidation of PARK7 protein]; Acetylcysteine inhibits the reaction [[Paraquat co-treated with Maneb] results in increased oxidation of PARK7 protein]; Acetylcysteine inhibits the reaction [Paraquat promotes the reaction [Quinones binds to PARK7 protein]]; Acetylcysteine inhibits the reaction [Rotenone results in increased expression of PARK7 protein]

PMID:18377993 PMID:20851755 PMID:32540572 PMID:34897981

NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970

G

poly (ADP-ribose) polymerase 1

increases cleavage
decreases expression
multiple interactions

Acetylcysteine results in increased cleavage of PARP1 protein
Acetylcysteine results in decreased expression of PARP1 protein modified form
Acetylcysteine inhibits the reaction [7-ketocholesterol results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [arsenic trioxide results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased cleavage of and results in increased activity of PARP1 protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [Cadmium results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [Chlorpyrifos results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [Gentamicins results in increased activity of PARP1 protein]
[Acetylcysteine affects the abundance of Reactive Oxygen Species] inhibits the reaction [sodium arsenite results in increased cleavage of PARP1 protein]; [Acetylcysteine results in increased susceptibility to 8-((4-chlorophenyl)thio)cyclic-3',5'-AMP] which results in increased cleavage of PARP1 protein; [Glucose deficiency co-treated with Acetylcysteine] results in increased cleavage of PARP1 protein; Acetylcysteine affects the reaction [[gambogic acid affects the reaction [ABCB1 protein affects the susceptibility to Doxorubicin]] which affects the cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [1,4-naphthoquinone analog results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [2'-benzoyloxycinnamaldehyde results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [2-hydroxy-3',5,5'-trimethoxychalcone results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [3-oxo-29-noroleana-1,9(11),12-trien-2,20-dicarbonitrile results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [4-chromone analog results in increased expression of PARP1 protein modified form]; Acetylcysteine inhibits the reaction [5-methylselenylmethyl-2'-deoxyuridine results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [5-phenylselenylmethyl-2'-deoxyuridine results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [[Arsenic Trioxide co-treated with Ethacrynic Acid] results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [[Arsenic Trioxide co-treated with phytosphingosine] results in increased activity of PARP1 protein]; Acetylcysteine inhibits the reaction [[Berberine co-treated with Cisplatin] results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [[cholix toxin, Vibrio cholerae co-treated with TNF protein] results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [[CSC-3436 co-treated with TNFSF10 protein] results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [[monomethylarsonous acid co-treated with dimethylarsinous acid co-treated with Arsenic Trioxide] results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [[S100A11 mutant form results in increased susceptibility to Cisplatin] which results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [[sodium arsenite co-treated with TNF protein] results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [[sulforaphane co-treated with Arsenic Trioxide] results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [[Sulindac co-treated with Arsenic Trioxide] results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [[TNFSF10 protein co-treated with gingerol] results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [[TNFSF10 protein co-treated with tanshinone] results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [[Verapamil co-treated with gambogic acid] results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [ABBV-744 results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [Acetaminophen results in increased expression of PARP1 mRNA]; Acetylcysteine inhibits the reaction [Acrylamide results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [Acrylonitrile results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [Antimycin A results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide promotes the reaction [Cisplatin results in increased cleavage of PARP1 protein]]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of PARP1 protein]; Acetylcysteine inhibits the reaction [Artesunate results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased cleavage of and results in increased activity of PARP1 protein]; Acetylcysteine inhibits the reaction [chloropicrin results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [Cisplatin promotes the reaction [Arsenic Trioxide results in increased cleavage of PARP1 protein]]; Acetylcysteine inhibits the reaction [Cisplatin results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [cobaltous chloride promotes the reaction [nickel chloride results in increased cleavage of PARP1 protein]]; Acetylcysteine inhibits the reaction [cobaltous chloride results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [cucurbitacin E results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [diallyl trisulfide results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [divinyl sulfone analog results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [Fenretinide results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [Fingolimod Hydrochloride results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [frenolicin B results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [Glucose results in increased activity of PARP1 protein]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [isoalantolactone results in increased expression of PARP1 protein modified form]; Acetylcysteine inhibits the reaction [isoliensinine results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [manumycin results in increased cleavage of PARP1]; Acetylcysteine inhibits the reaction [Methylmercury Compounds results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [Morpholines analog results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [N-methylisoindigotin results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [nickel chloride promotes the reaction [cobaltous chloride results in increased cleavage of PARP1 protein]]; Acetylcysteine inhibits the reaction [nickel chloride results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [Oligopeptides analog results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [osimertinib results in increased expression of PARP1 protein modified form]; Acetylcysteine inhibits the reaction [pendulone results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [phenethyl isothiocyanate results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [Plant Extracts results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [salvin results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [scutebarbatine A results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [shikonin results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [shogaol promotes the reaction [TNFSF10 protein results in increased cleavage of PARP1 protein]]; Acetylcysteine inhibits the reaction [shogaol results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [sinularin results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [sodium arsenite results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [tert-Butylhydroperoxide results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [thymoquinone results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [thymoquinone results in increased expression of PARP1 protein modified form]; Acetylcysteine inhibits the reaction [TNFSF10 protein results in increased expression of PARP1 protein modified form]; Acetylcysteine inhibits the reaction [tomentosin results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [Tosylphenylalanyl Chloromethyl Ketone results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [wedelolactone results in increased cleavage of PARP1 protein]; Acetylcysteine promotes the reaction [dihydromyricetin results in increased cleavage of PARP1 protein]; Acetylcysteine results in decreased susceptibility to [1-(3',4',5'-trimethoxyphenyl)-3-(3'',4''-dimethoxy-2'-hydroxyphenyl)propane results in increased cleavage of PARP1 protein]
Acetylcysteine inhibits the reaction [1,3-dichloro-2-propanol results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [[Mercuric Chloride co-treated with prolinedithiocarbamate] results in increased degradation of PARP1 protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased activity of PARP1 protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [Cadmium results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [cadmium sulfate results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [Diethylhexyl Phthalate results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [methylmercuric chloride results in decreased expression of PARP1 protein]; Acetylcysteine inhibits the reaction [Zinc Oxide analog results in increased cleavage of PARP1 protein]

PMID:11470263 PMID:14660655 PMID:14687664 PMID:15375156 PMID:15496615 More...

NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404

G

phosphoenolpyruvate carboxykinase 1

multiple interactions

Acetylcysteine inhibits the reaction [Malathion results in increased expression of PCK1 mRNA]

NCBI chr 3:161,930,256...161,936,205
Ensembl chr 3:161,930,256...161,936,191

G

protein-L-isoaspartate (D-aspartate) O-methyltransferase 1

multiple interactions

Acetylcysteine inhibits the reaction [Dopamine results in decreased expression of PCMT1 mRNA]; Acetylcysteine inhibits the reaction [Dopamine results in decreased expression of PCMT1 protein]

NCBI chr 1:2,111,756...2,160,354
Ensembl chr 1:2,111,763...2,159,201

G

proliferating cell nuclear antigen

multiple interactions

Acetylcysteine inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] which results in increased expression of PCNA protein]; Acetylcysteine inhibits the reaction [bisphenol A results in decreased activity of PCNA protein]
Acetylcysteine inhibits the reaction [Glyphosate results in increased expression of PCNA protein]

PMID:31551408 PMID:33485121 PMID:33797725

NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995

G

programmed cell death 4

multiple interactions

Acetylcysteine inhibits the reaction [[tungsten carbide analog co-treated with Cobalt analog] results in decreased expression of PDCD4 protein]
Acetylcysteine inhibits the reaction [chromium hexavalent ion results in decreased expression of PDCD4 mRNA]

PMID:23758151 PMID:27323401

NCBI chr 1:252,921,342...252,944,278
Ensembl chr 1:252,921,392...252,944,275

G

programmed cell death 6 interacting protein

multiple interactions

Acetylcysteine inhibits the reaction [hesperetin results in decreased expression of PDCD6IP protein]

NCBI chr 8:113,590,998...113,646,795
Ensembl chr 8:113,590,998...113,646,773

G

phosphodiesterase 6B

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of PDE6B mRNA

NCBI chr14:1,323,310...1,366,450
Ensembl chr14:1,323,310...1,366,450

G

platelet derived growth factor subunit B

multiple interactions

Acetylcysteine inhibits the reaction [Nickel analog promotes the reaction [PDGFB protein results in increased phosphorylation of MAPK1 protein]]; Acetylcysteine inhibits the reaction [Nickel analog promotes the reaction [PDGFB protein results in increased phosphorylation of MAPK3 protein]]; Acetylcysteine inhibits the reaction [PDGFB protein promotes the reaction [Nickel analog results in increased expression of CCL2 protein]]; Acetylcysteine inhibits the reaction [PDGFB protein promotes the reaction [Nickel analog results in increased expression of HIF1A protein]]
Acetylcysteine inhibits the reaction [Cadmium Chloride results in decreased expression of PDGFB protein]

PMID:22700867 PMID:26138014

NCBI chr 7:111,539,444...111,557,984
Ensembl chr 7:111,540,345...111,557,984

G

platelet derived growth factor receptor beta

multiple interactions

Acetylcysteine inhibits the reaction [sodium arsenite results in increased expression of PDGFRB mRNA]
Acetylcysteine inhibits the reaction [Copper Sulfate results in increased expression of PDGFRB mRNA]; Acetylcysteine inhibits the reaction [Copper Sulfate results in increased expression of PDGFRB protein]; Buthionine Sulfoximine inhibits the reaction [Acetylcysteine inhibits the reaction [Copper Sulfate results in increased expression of PDGFRB mRNA]]; Buthionine Sulfoximine inhibits the reaction [Acetylcysteine inhibits the reaction [Copper Sulfate results in increased expression of PDGFRB protein]]

PMID:21134390 PMID:23392711

NCBI chr18:54,499,962...54,538,840
Ensembl chr18:54,499,964...54,538,843

G

pyruvate dehydrogenase E1 subunit alpha 1

multiple interactions

Acetylcysteine inhibits the reaction [epigallocatechin gallate results in decreased expression of PDHA1 mRNA]; Acetylcysteine inhibits the reaction [epigallocatechin gallate results in decreased expression of PDHA1 protein]

NCBI chr X:34,700,481...34,714,309
Ensembl chr X:34,700,409...34,714,311

G

pyruvate dehydrogenase kinase 1

multiple interactions

Acetylcysteine inhibits the reaction [2,3',4,4',5-pentachlorobiphenyl results in increased expression of PDK1 mRNA]; Acetylcysteine inhibits the reaction [2,4,5,2',4',5'-hexachlorobiphenyl results in increased expression of PDK1 mRNA]; Acetylcysteine inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PDK1 mRNA]; Acetylcysteine inhibits the reaction [Curcumin results in increased phosphorylation of PDK1 protein]; Acetylcysteine inhibits the reaction [DDT results in increased expression of PDK1 mRNA]

PMID:17171638 PMID:30821169 PMID:31251971 PMID:31724279

NCBI chr 3:56,705,824...56,733,040
Ensembl chr 3:56,705,871...56,733,038

G

pyruvate dehydrogenase kinase 4

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of PDK4 mRNA

NCBI chr 4:33,591,796...33,601,798
Ensembl chr 4:33,589,799...33,601,850

G

PDZ and LIM domain 5

decreases expression

Acetylcysteine results in decreased expression of PDLIM5 mRNA

NCBI chr 2:230,952,251...231,120,329
Ensembl chr 2:230,952,248...231,120,275

G

peroxisomal biogenesis factor 11 alpha

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of PEX11A mRNA; Acetylcysteine inhibits the reaction [[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of PEX11A mRNA]

NCBI chr 1:133,680,091...133,687,172
Ensembl chr 1:133,680,091...133,687,172

G

phosphogluconate dehydrogenase

increases activity

Acetylcysteine results in increased activity of PGD protein

NCBI chr 5:159,582,746...159,598,945
Ensembl chr 5:159,561,271...159,742,778

G

progesterone receptor

multiple interactions
decreases secretion

Acetylcysteine inhibits the reaction [SOD2 protein affects the expression of PGR mRNA]
Acetylcysteine results in decreased secretion of PGR protein
Acetylcysteine inhibits the reaction [LHB protein results in increased abundance of PGR mRNA]; Acetylcysteine inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased secretion of PGR protein]

PMID:18829485 PMID:21220312 PMID:30648648

NCBI chr 8:6,072,673...6,131,552
Ensembl chr 8:6,072,673...6,131,344

G

phosphatidylinositol glycan anchor biosynthesis, class A

increases expression

Acetylcysteine results in increased expression of PIGA mRNA

NCBI chr X:30,043,033...30,055,861
Ensembl chr X:30,042,343...30,055,804

G

phosphoinositide-3-kinase regulatory subunit 1

multiple interactions

Acetylcysteine promotes the reaction [PIK3R1 protein modified form inhibits the reaction [butylphen results in increased abundance of Reactive Oxygen Species]]; Acetylcysteine promotes the reaction [PIK3R1 protein modified form inhibits the reaction [butylphen results in increased expression of IL1A protein]]; Acetylcysteine promotes the reaction [PIK3R1 protein modified form inhibits the reaction [butylphen results in increased expression of TNF protein]]; Acetylcysteine promotes the reaction [PIK3R1 protein modified form inhibits the reaction [hydroquinone results in increased abundance of Reactive Oxygen Species]]; Acetylcysteine promotes the reaction [PIK3R1 protein modified form inhibits the reaction [hydroquinone results in increased expression of IL1A protein]]; Acetylcysteine promotes the reaction [PIK3R1 protein modified form inhibits the reaction [hydroquinone results in increased expression of TNF protein]]

NCBI chr 2:32,878,942...32,963,668
Ensembl chr 2:32,882,032...32,963,631

G

Pim-1 proto-oncogene, serine/threonine kinase

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of PIM1 mRNA

NCBI chr20:7,554,921...7,559,174
Ensembl chr20:7,554,921...7,559,174

G

Pim-2 proto-oncogene, serine/threonine kinase

increases expression

Acetylcysteine results in increased expression of PIM2 mRNA

NCBI chr X:14,617,582...14,622,851
Ensembl chr X:14,617,582...14,622,851

G

PTEN induced kinase 1

multiple interactions

Acetylcysteine inhibits the reaction [[Aluminum Chloride results in increased abundance of Aluminum] which results in increased expression of PINK1 mRNA]; Acetylcysteine inhibits the reaction [Cadmium results in increased expression of PINK1]; Acetylcysteine inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of PINK1 protein]; Acetylcysteine inhibits the reaction [tricalcium phosphate results in increased expression of PINK1 protein]
Acetylcysteine inhibits the reaction [Cadmium results in increased expression of PINK1 mRNA]; Acetylcysteine inhibits the reaction [Lead results in increased expression of PINK1 mRNA]
Acetylcysteine inhibits the reaction [quinone results in increased expression of PINK1 protein]

PMID:25464205 PMID:29567065 PMID:34547296 PMID:34816377 PMID:37678662 More...

NCBI chr 5:150,530,523...150,542,635
Ensembl chr 5:150,530,523...150,542,635

G

prolactin induced protein

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of PIP mRNA

NCBI chr 4:70,787,627...70,791,921
Ensembl chr 4:70,787,627...70,791,921

G

paired Ig-like receptor B

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of LILRB3 mRNA

NCBI chr 1:65,499,195...65,506,666
Ensembl chr 1:65,499,195...65,506,666

G

piwi-like RNA-mediated gene silencing 4

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of PIWIL4 mRNA

NCBI chr 8:11,536,520...11,579,883
Ensembl chr 8:11,536,520...11,579,761

G

pyruvate kinase M1/2

multiple interactions

Acetylcysteine inhibits the reaction [NOX4 protein promotes the reaction [[Lipopolysaccharides co-treated with IFNG1 protein] results in increased expression of PKM protein]]; Acetylcysteine inhibits the reaction [quinone results in increased degradation of PKM protein]
Acetylcysteine inhibits the reaction [2,3',4,4',5-pentachlorobiphenyl results in increased expression of PKM mRNA]; Acetylcysteine inhibits the reaction [2,3',4,4',5-pentachlorobiphenyl results in increased expression of PKM protein]; Acetylcysteine inhibits the reaction [2,4,5,2',4',5'-hexachlorobiphenyl results in increased expression of PKM protein]; Acetylcysteine inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PKM mRNA]; Acetylcysteine inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of PKM protein]; Acetylcysteine inhibits the reaction [DDT results in increased expression of and affects the localization of PKM protein alternative form]; Acetylcysteine inhibits the reaction [DDT results in increased expression of PKM mRNA alternative form]

PMID:25437431 PMID:28284859 PMID:30821169 PMID:31251971 PMID:31724279 More...

NCBI chr 8:60,057,629...60,079,600
Ensembl chr 8:60,057,402...60,079,599

G

phospholipase A2 group IVA

multiple interactions

Acetylcysteine inhibits the reaction [Ditiocarb results in increased expression of PLA2G4A mRNA]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in decreased expression of PLA2G4A mRNA]

PMID:15683734 PMID:16603213

NCBI chr13:61,877,818...62,022,261
Ensembl chr13:61,877,813...62,022,266

G

plasminogen activator, urokinase

decreases expression
multiple interactions

Acetylcysteine results in decreased expression of PLAU mRNA
Acetylcysteine inhibits the reaction [arsenic trioxide results in decreased secretion of PLAU protein]

PMID:15962302 PMID:16084531

NCBI chr15:3,456,230...3,462,732
Ensembl chr15:3,456,232...3,462,775

G

plasminogen activator, urokinase receptor

multiple interactions

Acetylcysteine inhibits the reaction [Nicotine results in increased expression of PLAUR mRNA]

NCBI chr 1:80,053,440...80,068,384
Ensembl chr 1:80,050,324...80,068,595

G

phospholipase D1

multiple interactions

Acetylcysteine inhibits the reaction [PLD1 protein promotes the reaction [cobaltous chloride results in increased expression of PTGS2 protein]]

NCBI chr 2:110,849,205...111,047,304
Ensembl chr 2:110,893,608...111,047,692

G

phospholipase D2

multiple interactions

Acetylcysteine inhibits the reaction [PLD2 protein promotes the reaction [cobaltous chloride results in increased expression of PTGS2 protein]]

NCBI chr10:55,256,326...55,274,192
Ensembl chr10:55,256,359...55,272,808

G

perilipin 2

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of PLIN2 mRNA

NCBI chr 5:101,156,648...101,211,738
Ensembl chr 5:101,154,411...101,242,319

G

phospholipid phosphatase related 1

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of PLPPR1 mRNA

NCBI chr 5:63,437,457...63,725,286
Ensembl chr 5:63,437,816...63,763,835

G

phorbol-12-myristate-13-acetate-induced protein 1

multiple interactions

Acetylcysteine inhibits the reaction [2-xylene results in increased expression of PMAIP1 mRNA]; Acetylcysteine inhibits the reaction [Benzene results in increased expression of PMAIP1 mRNA]; Acetylcysteine inhibits the reaction [elesclomol results in increased expression of PMAIP1 mRNA]; Acetylcysteine inhibits the reaction [Toluene results in increased expression of PMAIP1 mRNA]

PMID:18723479 PMID:21144877

NCBI chr18:59,986,020...59,992,434
Ensembl chr18:59,986,017...59,992,429

G

patatin-like phospholipase domain containing 3

multiple interactions

Acetylcysteine inhibits the reaction [Dietary Fats results in increased expression of PNPLA3 mRNA]

NCBI chr 7:115,293,538...115,314,077
Ensembl chr 7:115,293,538...115,314,077

G

patatin-like phospholipase domain containing 5

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of PNPLA5 mRNA

NCBI chr 7:115,246,050...115,257,039
Ensembl chr 7:115,246,050...115,257,039

G

proline-rich nuclear receptor coactivator 1

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of PNRC1 mRNA

NCBI chr 5:47,647,070...47,657,832
Ensembl chr 5:47,647,071...47,650,161

G

RNA polymerase I and III subunit C

multiple interactions

Acetylcysteine inhibits the reaction [Paraquat results in decreased methylation of POLR1C mRNA]

NCBI chr 9:14,735,740...14,739,852
Ensembl chr 9:14,735,714...14,739,852

G

proopiomelanocortin

multiple interactions

Acetylcysteine inhibits the reaction [POMC protein promotes the reaction [cobaltous chloride results in increased activity of CASP3 protein]]

NCBI chr 6:26,939,844...26,945,666
Ensembl chr 6:26,939,837...26,945,664

G

paraoxonase 1

multiple interactions

Acetylcysteine affects the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased activity of PON1 protein]

NCBI chr 4:33,294,737...33,325,759
Ensembl chr 4:33,294,722...33,321,360

G

paraoxonase 2

multiple interactions

Acetylcysteine inhibits the reaction [iron(II)-ascorbic acid complex results in increased expression of PON2 protein]

NCBI chr 4:33,389,702...33,425,186
Ensembl chr 4:33,389,714...33,425,248

G

periostin

decreases expression

Acetylcysteine results in decreased expression of POSTN mRNA

NCBI chr 2:138,527,714...138,559,098
Ensembl chr 2:138,527,696...138,559,099

G

POU class 5 homeobox 1

multiple interactions

Acetylcysteine inhibits the reaction [decabromobiphenyl ether results in decreased expression of POU5F1 protein]; Acetylcysteine inhibits the reaction [Particulate Matter results in decreased expression of POU5F1 protein]

PMID:26206603 PMID:32745510

NCBI chr20:3,223,128...3,227,891
Ensembl chr20:3,223,129...3,227,891

G

peroxisome proliferator-activated receptor gamma

increases expression
multiple interactions

Acetylcysteine results in increased expression of PPARG mRNA; Acetylcysteine results in increased expression of PPARG protein
Acetylcysteine inhibits the reaction [[Carbon Monoxide results in increased abundance of Reactive Oxygen Species] which results in increased sumoylation of PPARG protein]; Acetylcysteine inhibits the reaction [INS1 protein results in increased expression of PPARG protein]
Acetylcysteine inhibits the reaction [[[15-deoxyprostaglandin J2 results in increased activity of PPARG protein] which results in decreased expression of SOD2 protein] which results in increased abundance of Reactive Oxygen Species]; Acetylcysteine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of PPARG protein]
Acetylcysteine inhibits the reaction [yttrium chloride results in decreased expression of PPARG protein]; Buthionine Sulfoximine inhibits the reaction [Acetylcysteine results in increased expression of PPARG mRNA]; Buthionine Sulfoximine inhibits the reaction [Acetylcysteine results in increased expression of PPARG protein]

PMID:16945329 PMID:17602960 PMID:22046279 PMID:23964924 PMID:27117918 More...

NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468

G

PPARG coactivator 1 alpha

multiple interactions

Acetylcysteine inhibits the reaction [Flavonoids results in increased expression of PPARGC1A protein]; Acetylcysteine inhibits the reaction [Polystyrenes analog results in decreased expression of PPARGC1A protein]
Acetylcysteine inhibits the reaction [Atorvastatin results in increased expression of PPARGC1A mRNA]; Acetylcysteine inhibits the reaction [bisphenol A results in decreased expression of PPARGC1A protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in decreased expression of PPARGC1A mRNA]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in decreased expression of PPARGC1A protein]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in decreased expression of PPARGC1A protein]; Acetylcysteine inhibits the reaction [Monocrotophos results in decreased expression of PPARGC1A mRNA]; Acetylcysteine inhibits the reaction [sodium bisulfite results in decreased expression of PPARGC1A mRNA]

PMID:21775390 PMID:23063593 PMID:26980303 PMID:30104959 PMID:30641872 More...

NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656

G

PPARG coactivator 1 beta

multiple interactions

Acetylcysteine inhibits the reaction [Cadmium Chloride results in decreased expression of PPARGC1B mRNA]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in decreased expression of PPARGC1B protein]

NCBI chr18:54,758,891...54,861,103
Ensembl chr18:54,758,902...54,861,194

G

pro-platelet basic protein

multiple interactions

Acetylcysteine promotes the reaction [Cadmium Chloride results in decreased secretion of PPBP protein]

NCBI chr14:17,302,326...17,303,130
Ensembl chr14:17,302,326...17,303,130

G

protein phosphatase 1, regulatory subunit 15A

multiple interactions

Acetylcysteine inhibits the reaction [4-hydroxy-2-nonenal results in increased expression of PPP1R15A mRNA]
Acetylcysteine inhibits the reaction [arsenite promotes the reaction [TARDBP protein binds to PPP1R15A protein]]

PMID:24291486 PMID:29109149

NCBI chr 1:96,000,053...96,003,128
Ensembl chr 1:96,000,058...96,003,171

G

protein phosphatase 2 catalytic subunit alpha

multiple interactions

Acetylcysteine inhibits the reaction [Cadmium Chloride results in decreased methylation of and results in increased phosphorylation of PPP2CA protein]

NCBI chr10:36,358,110...36,377,864
Ensembl chr10:36,358,101...36,377,862

G

protein phosphatase 2 scaffold subunit A beta

multiple interactions

Acetylcysteine inhibits the reaction [Cadmium Chloride results in decreased expression of PPP2R1B protein]

NCBI chr 8:51,195,860...51,228,442
Ensembl chr 8:51,186,717...51,228,485

G

protein phosphatase 5, catalytic subunit

multiple interactions

Acetylcysteine inhibits the reaction [Cadmium Chloride results in decreased expression of PPP5C protein]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in decreased expression of PPP5C protein]

PMID:18703135 PMID:19038359

NCBI chr 1:77,690,203...77,714,507
Ensembl chr 1:77,690,208...77,714,456

G

peroxiredoxin 1

multiple interactions

Acetylcysteine inhibits the reaction [[frenolicin B results in decreased activity of PRDX1 protein] which results in increased abundance of Reactive Oxygen Species]

NCBI chr 5:130,147,258...130,162,856
Ensembl chr 5:130,147,204...130,162,856

G

peroxiredoxin 3

multiple interactions

Acetylcysteine inhibits the reaction [Thiostrepton affects the expression of PRDX3 protein modified form]

NCBI chr 1:260,001,642...260,014,064
Ensembl chr 1:260,001,637...260,014,111

G

peroxiredoxin 5

multiple interactions

Acetylcysteine inhibits the reaction [PRKAA2 protein affects the reaction [[Air Pollutants results in increased abundance of Particulate Matter] which results in decreased expression of PRDX5 protein]]

NCBI chr 1:204,099,826...204,103,589
Ensembl chr 1:204,099,826...204,114,268

G

proline rich protein HaeIII subfamily 1

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of PRH1 mRNA

NCBI chr 4:166,543,755...166,547,614

G

protein kinase AMP-activated catalytic subunit alpha 1

multiple interactions

Acetylcysteine inhibits the reaction [Cadmium Chloride results in decreased phosphorylation of PRKAA1 protein]
Acetylcysteine inhibits the reaction [Cadmium Chloride results in decreased phosphorylation of PRKAA1 protein]; Acetylcysteine inhibits the reaction [cobaltous chloride results in increased phosphorylation of PRKAA1 protein]; Acetylcysteine inhibits the reaction [dorsomorphin results in decreased expression of PRKAA1 mRNA]; Acetylcysteine inhibits the reaction [Quercetin results in increased phosphorylation of and results in increased activity of PRKAA1 protein]; Acetylcysteine inhibits the reaction [Quercetin results in increased phosphorylation of PRKAA1 protein]; Acetylcysteine inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of and results in increased phosphorylation of PRKAA1 protein]

PMID:19293639 PMID:20083342 PMID:21195169 PMID:24386346 PMID:24535669 More...

NCBI chr 2:54,240,298...54,275,978
Ensembl chr 2:54,240,137...54,275,978

G

protein kinase AMP-activated catalytic subunit alpha 2

multiple interactions

Acetylcysteine inhibits the reaction [[PRKAA2 protein affects the susceptibility to [Air Pollutants results in increased abundance of Particulate Matter]] which results in increased phosphorylation of RELA protein]; Acetylcysteine inhibits the reaction [PRKAA2 protein affects the reaction [[Air Pollutants results in increased abundance of Particulate Matter] which results in decreased expression of PRDX5 protein]]; Acetylcysteine inhibits the reaction [PRKAA2 protein affects the reaction [[Air Pollutants results in increased abundance of Particulate Matter] which results in increased expression of TNF protein]]

NCBI chr 5:119,807,992...119,879,987
Ensembl chr 5:119,813,226...119,879,543

G

protein kinase C, delta

multiple interactions

Acetylcysteine inhibits the reaction [Curcumin results in increased phosphorylation of PRKCD protein]; Acetylcysteine inhibits the reaction [Ursodeoxycholic Acid results in increased localization of PRKCD protein]
Acetylcysteine inhibits the reaction [3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl ester results in increased cleavage of and results in increased phosphorylation of PRKCD protein]
Acetylcysteine inhibits the reaction [Cadmium results in increased phosphorylation of PRKCD protein]

PMID:17171638 PMID:21362627 PMID:27658547 PMID:37308051

NCBI chr16:5,769,217...5,799,380
Ensembl chr16:5,769,215...5,799,352

G

protein kinase C, epsilon

multiple interactions

Acetylcysteine inhibits the reaction [NGF protein results in increased localization of and results in increased activity of PRKCE protein]

NCBI chr 6:7,965,048...8,451,966
Ensembl chr 6:7,965,048...8,451,719

G

protein kinase, DNA-activated, catalytic subunit

multiple interactions
increases expression

Acetylcysteine inhibits the reaction [usnic acid results in increased expression of PRKDC protein]
Acetylcysteine results in increased expression of PRKDC protein

NCBI chr11:85,040,790...85,258,357
Ensembl chr11:85,040,792...85,257,952

G

parkin RBR E3 ubiquitin protein ligase

multiple interactions

Acetylcysteine inhibits the reaction [[Aluminum Chloride results in increased abundance of Aluminum] which results in increased expression of PRKN mRNA]; Acetylcysteine inhibits the reaction [Cadmium results in increased expression of PRKN]; Acetylcysteine inhibits the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone affects the localization of PRKN protein]; Acetylcysteine inhibits the reaction [Paraquat results in increased expression of PRKN mRNA]
Acetylcysteine inhibits the reaction [Cadmium results in increased expression of PRKN mRNA]; Acetylcysteine inhibits the reaction [Lead results in increased expression of PRKN mRNA]
Acetylcysteine inhibits the reaction [quinone results in increased expression of PRKN protein]

PMID:22872702 PMID:25464205 PMID:29567065 PMID:31368586 PMID:34547296 More...

NCBI chr 1:48,688,651...49,882,520
Ensembl chr 1:48,690,556...49,882,555

G

prolactin

multiple interactions

Acetylcysteine inhibits the reaction [sodium arsenite results in decreased secretion of PRL protein]

NCBI chr17:37,859,999...37,870,062
Ensembl chr17:37,860,007...37,870,062

G

prolactin receptor

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of PRLR mRNA; Acetylcysteine inhibits the reaction [[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of PRLR mRNA]

NCBI chr 2:59,134,147...59,324,719
Ensembl chr 2:59,134,588...59,324,718

G

phosphoserine aminotransferase 1

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of PSAT1 mRNA; Acetylcysteine inhibits the reaction [[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of PSAT1 mRNA]

NCBI chr 1:213,196,709...213,218,564
Ensembl chr 1:213,196,709...213,218,682

G

proteasome 26S subunit, non-ATPase 1

multiple interactions

Acetylcysteine inhibits the reaction [Paraquat results in decreased methylation of PSMD1 mRNA]

NCBI chr 9:86,709,714...86,785,213
Ensembl chr 9:86,709,947...86,785,211

G

proteasome activator subunit 4

multiple interactions

Acetylcysteine inhibits the reaction [elesclomol results in increased expression of PSME4 mRNA]

NCBI chr14:104,505,716...104,609,410
Ensembl chr14:104,505,716...104,609,408

G

phosphatase and tensin homolog

multiple interactions

Acetylcysteine inhibits the reaction [Antimycin A results in increased expression of PTEN mRNA]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in decreased expression of PTEN protein]
Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased degradation of and results in decreased expression of PTEN protein]; Acetylcysteine inhibits the reaction [Cadmium results in increased degradation of and results in decreased expression of PTEN protein]; Acetylcysteine inhibits the reaction [Lipopolysaccharides promotes the reaction [PTEN gene mutant form results in increased secretion of GPT protein]]

PMID:21195169 PMID:24449419 PMID:27022031 PMID:35430258

NCBI chr 1:230,630,443...230,697,070
Ensembl chr 1:230,630,338...230,696,838

G

prostaglandin-endoperoxide synthase 2

decreases expression
multiple interactions

Acetylcysteine results in decreased expression of PTGS2 mRNA
Acetylcysteine inhibits the reaction [1,3-dichloro-2-propanol results in increased expression of PTGS2 protein]; Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased expression of PTGS2 mRNA] which results in increased abundance of Dinoprostone]; Acetylcysteine inhibits the reaction [benzanthrone results in increased expression of PTGS2 protein]; Acetylcysteine inhibits the reaction [Cadmium results in increased expression of PTGS2 mRNA]; Acetylcysteine inhibits the reaction [Cadmium results in increased expression of PTGS2 protein]; Acetylcysteine inhibits the reaction [cadmium sulfate results in increased expression of PTGS2]; Acetylcysteine inhibits the reaction [Drugs, Chinese Herbal inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of PTGS2 protein]]; Acetylcysteine inhibits the reaction [Endosulfan results in increased expression of PTGS2 mRNA]; Acetylcysteine inhibits the reaction [Endosulfan results in increased expression of PTGS2 protein]; Acetylcysteine inhibits the reaction [Humic Substances results in increased expression of PTGS2 mRNA]; Acetylcysteine inhibits the reaction [Humic Substances results in increased expression of PTGS2 protein]; Acetylcysteine inhibits the reaction [JP8 aviation fuel results in increased expression of PTGS2 mRNA]; Acetylcysteine inhibits the reaction [LHB protein results in increased abundance of PTGS2 mRNA]; Acetylcysteine inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of PTGS2 protein]; Acetylcysteine inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of PTGS2 mRNA]; Acetylcysteine inhibits the reaction [Sodium Chloride results in increased expression of PTGS2 protein]; Acetylcysteine promotes the reaction [3-methylquercetin inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of PTGS2 protein]]; Polymyxin B promotes the reaction [Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of PTGS2 mRNA]]
Acetylcysteine inhibits the reaction [2-aminodiphenyl results in increased expression of PTGS2 protein]; Acetylcysteine inhibits the reaction [[2-hydroxyestradiol co-treated with 4-hydroxyestradiol] results in increased expression of PTGS2 mRNA]; Acetylcysteine inhibits the reaction [[Formaldehyde co-treated with eugenol, zinc oxide dental cavity lining] results in increased expression of PTGS2 mRNA]; Acetylcysteine inhibits the reaction [[IL1B protein co-treated with Oligomycins] results in increased expression of PTGS2 protein]; Acetylcysteine inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] which results in increased expression of PTGS2 mRNA]; Acetylcysteine inhibits the reaction [acenaphthenequinone results in increased expression of PTGS2 protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in decreased expression of PTGS2 mRNA]; Acetylcysteine inhibits the reaction [Benzene results in increased expression of PTGS2 protein]; Acetylcysteine inhibits the reaction [bisphenol A results in increased expression of PTGS2 mRNA]; Acetylcysteine inhibits the reaction [bisphenol A results in increased expression of PTGS2 protein]; Acetylcysteine inhibits the reaction [Chlorpyrifos results in increased expression of PTGS2 protein]; Acetylcysteine inhibits the reaction [cobaltous chloride affects the localization of PTGS2 protein]; Acetylcysteine inhibits the reaction [cobaltous chloride results in increased expression of PTGS2 protein]; Acetylcysteine inhibits the reaction [dentinol results in increased expression of PTGS2 mRNA]; Acetylcysteine inhibits the reaction [Estradiol promotes the reaction [[2-hydroxyestradiol co-treated with 4-hydroxyestradiol] results in increased expression of PTGS2 mRNA]]; Acetylcysteine inhibits the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein]; Acetylcysteine inhibits the reaction [manganese chloride results in increased expression of PTGS2 protein]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of PTGS2 mRNA]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of PTGS2 protein]; Acetylcysteine inhibits the reaction [PLD1 protein promotes the reaction [cobaltous chloride results in increased expression of PTGS2 protein]]; Acetylcysteine inhibits the reaction [PLD2 protein promotes the reaction [cobaltous chloride results in increased expression of PTGS2 protein]]; Acetylcysteine inhibits the reaction [Silicon Dioxide results in increased expression of PTGS2 protein]; Acetylcysteine inhibits the reaction [sodium arsenite results in increased expression of PTGS2 protein]; Acetylcysteine inhibits the reaction [Styrene results in increased expression of PTGS2 protein]; Acetylcysteine inhibits the reaction [titanium dioxide results in increased expression of PTGS2 protein]; Acetylcysteine inhibits the reaction [Tobacco Smoke Pollution analog results in increased expression of PTGS2 mRNA]; Acetylcysteine inhibits the reaction [Toluene results in increased expression of PTGS2 protein]; Acetylcysteine promotes the reaction [Particulate Matter results in increased expression of PTGS2 mRNA]
Acetylcysteine inhibits the reaction [cadmium sulfate results in increased expression of PTGS2 mRNA]; Acetylcysteine inhibits the reaction [cadmium sulfate results in increased expression of PTGS2 protein]; Acetylcysteine inhibits the reaction [Nicotine results in increased expression of PTGS2 protein]

PMID:14687664 PMID:15576159 PMID:15934011 PMID:16024921 PMID:16084531 More...

NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188

G

protein tyrosine kinase 2

multiple interactions

Acetylcysteine inhibits the reaction [[[Thimerosal results in increased abundance of Reactive Oxygen Species] which results in increased activity of CASP3 protein] which results in increased cleavage of PTK2 protein]

NCBI chr 7:105,126,725...105,331,848
Ensembl chr 7:105,126,728...105,331,783

G

protein tyrosine kinase 2 beta

multiple interactions

Acetylcysteine inhibits the reaction [TNF protein results in decreased phosphorylation of PTK2B protein]

NCBI chr15:40,360,722...40,481,235
Ensembl chr15:40,360,723...40,481,282

G

protein tyrosine kinase 6

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of PTK6 mRNA

NCBI chr 3:168,307,073...168,315,664
Ensembl chr 3:168,307,073...168,315,664

G

protein tyrosine phosphatase, non-receptor type 1

multiple interactions

Acetylcysteine inhibits the reaction [Arsenic Trioxide promotes the reaction [Pamidronate results in decreased expression of and results in decreased activity of PTPN1 protein]]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in decreased expression of and results in decreased activity of PTPN1 protein]; Acetylcysteine inhibits the reaction [Pamidronate promotes the reaction [Arsenic Trioxide results in decreased expression of and results in decreased activity of PTPN1 protein]]; Acetylcysteine inhibits the reaction [Pamidronate results in decreased expression of and results in decreased activity of PTPN1 protein]; Acetylcysteine inhibits the reaction [Pyruvaldehyde results in increased expression of PTPN1 protein]

PMID:22917016 PMID:32337366

NCBI chr 3:156,638,811...156,687,503
Ensembl chr 3:156,638,769...156,687,504

G

PYD and CARD domain containing

multiple interactions
increases expression

Acetylcysteine inhibits the reaction [2,3,5-trichloro-6-phenyl-(1,4)benzoquinone results in increased expression of PYCARD protein]; Acetylcysteine inhibits the reaction [Acrolein promotes the reaction [Lipopolysaccharides results in increased expression of PYCARD protein]]; Acetylcysteine inhibits the reaction [Acrolein results in increased expression of PYCARD protein]; Acetylcysteine inhibits the reaction [Chlorpyrifos results in increased expression of PYCARD protein]; Acetylcysteine inhibits the reaction [Ethanol results in increased expression of PYCARD protein]; Acetylcysteine inhibits the reaction [hydroquinone results in increased expression of PYCARD protein]; Acetylcysteine inhibits the reaction [Lipopolysaccharides results in increased expression of PYCARD protein]; Quercetin promotes the reaction [Acetylcysteine inhibits the reaction [Lipopolysaccharides results in increased expression of PYCARD protein]]
Acetylcysteine results in increased expression of PYCARD protein

PMID:26079697 PMID:26435000 PMID:30977640 PMID:34791735 PMID:36055550 More...

NCBI chr 1:182,601,657...182,603,013
Ensembl chr 1:182,601,174...182,602,955

G

glycogen phosphorylase L

multiple interactions

Acetylcysteine inhibits the reaction [Malathion results in increased expression of PYGL mRNA]

NCBI chr 6:88,697,598...88,740,260
Ensembl chr 6:88,697,593...88,740,310

G

RAB24, member RAS oncogene family

multiple interactions

Acetylcysteine inhibits the reaction [Tobacco Smoke Pollution results in increased expression of RAB24 protein]

NCBI chr17:9,308,471...9,310,553
Ensembl chr17:9,308,525...9,310,553

G

RAB30, member RAS oncogene family

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of RAB30 mRNA; Acetylcysteine inhibits the reaction [[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of RAB30 mRNA]

NCBI chr 1:146,803,719...146,898,369
Ensembl chr 1:146,803,714...146,892,181

G

RAB7A, member RAS oncogene family

multiple interactions

Acetylcysteine inhibits the reaction [cadmium acetate affects the localization of [RAB7A protein co-treated with MAP1LC3B protein]]

NCBI chr 4:120,461,966...120,510,756
Ensembl chr 4:120,461,963...120,506,889

G

Rac family small GTPase 1

multiple interactions
decreases expression

Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of RAC1 protein]
Acetylcysteine results in decreased expression of RAC1 protein

NCBI chr12:11,037,028...11,057,251
Ensembl chr12:11,036,698...11,057,251

G

Rac family small GTPase 2

multiple interactions

Acetylcysteine inhibits the reaction [Resveratrol affects the localization of RAC2 protein]

NCBI chr 7:110,101,344...110,128,718
Ensembl chr 7:110,116,260...110,128,720

G

receptor for activated C kinase 1

multiple interactions

Acetylcysteine inhibits the reaction [bisphenol A results in increased expression of RACK1 mRNA]

NCBI chr10:33,169,415...33,174,896
Ensembl chr10:33,169,169...33,174,975

G

RAD1 checkpoint DNA exonuclease

multiple interactions

Acetylcysteine inhibits the reaction [Acetaminophen results in increased expression of RAD1 mRNA]

NCBI chr 2:59,461,597...59,469,707
Ensembl chr 2:59,461,607...59,469,689

G

RAD18 E3 ubiquitin protein ligase

multiple interactions

Acetylcysteine inhibits the reaction [4-biphenylamine results in decreased expression of RAD18 protein]

NCBI chr 4:145,735,654...145,821,102
Ensembl chr 4:145,735,654...145,821,069

G

RAD51 paralog B

multiple interactions

Acetylcysteine inhibits the reaction [Acetaminophen results in increased expression of RAD51B mRNA]

NCBI chr 6:98,096,525...98,640,988
Ensembl chr 6:98,098,868...98,640,979

G

RAD54 like

multiple interactions

Acetylcysteine inhibits the reaction [Antimycin A results in increased expression of RAD54L mRNA]

NCBI chr 5:129,575,431...129,605,100
Ensembl chr 5:129,575,378...129,605,070

G

RAD9 checkpoint clamp component A

multiple interactions

Acetylcysteine inhibits the reaction [Acetaminophen results in decreased expression of RAD9A mRNA]

NCBI chr 1:201,488,511...201,553,582
Ensembl chr 1:201,487,136...201,553,608

G

Raf-1 proto-oncogene, serine/threonine kinase

multiple interactions

Acetylcysteine inhibits the reaction [NSC 680410 results in decreased expression of RAF1 protein]
Acetylcysteine inhibits the reaction [tubocapsenolide A results in increased degradation of RAF1 protein]
[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in increased expression of RAF1 mRNA

PMID:16481037 PMID:18442981 PMID:22129741

NCBI chr 4:148,679,534...148,740,265
Ensembl chr 4:148,679,530...148,740,317

G

RB transcriptional corepressor 1

multiple interactions

Acetylcysteine inhibits the reaction [5-nitroso-8-quinolinol results in decreased expression of RB1 protein modified form]; Acetylcysteine inhibits the reaction [Doxorubicin results in decreased phosphorylation of RB1 protein]; Acetylcysteine inhibits the reaction [Levamisole results in decreased expression of RB1 protein]
Acetylcysteine inhibits the reaction [[Maneb co-treated with Paraquat] results in increased expression of RB1 mRNA]; Acetylcysteine inhibits the reaction [Maneb results in increased expression of RB1 mRNA]; Acetylcysteine inhibits the reaction [Paraquat results in increased expression of RB1 mRNA]

PMID:11139434 PMID:16497787 PMID:22927544 PMID:29859004

NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302

G

REL proto-oncogene, NF-kB subunit

multiple interactions

Acetylcysteine inhibits the reaction [Lipopolysaccharides affects the localization of REL protein]
Acetylcysteine inhibits the reaction [Norepinephrine affects the localization of REL protein]

PMID:11970852 PMID:23114885

NCBI chr14:97,690,105...97,721,194
Ensembl chr14:97,695,161...97,720,892

G

RELA proto-oncogene, NF-kB subunit

multiple interactions
increases phosphorylation
decreases phosphorylation
increases activity
increases glutathionylation

Acetylcysteine inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of RELA mRNA]; Acetylcysteine inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of RELA protein]; Acetylcysteine inhibits the reaction [[Potassium Dichromate results in increased abundance of chromium hexavalent ion] which results in increased phosphorylation of RELA protein]; Acetylcysteine inhibits the reaction [[PRKAA2 protein affects the susceptibility to [Air Pollutants results in increased abundance of Particulate Matter]] which results in increased phosphorylation of RELA protein]; Acetylcysteine inhibits the reaction [endotoxin, Escherichia coli affects the localization of and results in increased activity of RELA protein]; Acetylcysteine inhibits the reaction [JP8 aviation fuel results in increased activity of RELA protein]; Acetylcysteine inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of RELA mRNA]; Acetylcysteine inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of RELA protein]; Acetylcysteine inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of RELA protein]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased phosphorylation of RELA protein]; Acetylcysteine inhibits the reaction [TNF protein results in increased phosphorylation of RELA protein]; Acetylcysteine promotes the reaction [Particulate Matter results in decreased phosphorylation of RELA protein]
Acetylcysteine results in increased phosphorylation of RELA protein
Acetylcysteine results in decreased phosphorylation of RELA protein
Acetylcysteine inhibits the reaction [7-ketocholesterol results in increased expression of and results in increased phosphorylation of RELA protein]; Acetylcysteine inhibits the reaction [Acrylamide results in increased expression of and affects the localization of RELA protein]; Acetylcysteine inhibits the reaction [beta-hexachlorocyclohexane affects the localization of RELA protein]; Acetylcysteine inhibits the reaction [Doxorubicin results in increased phosphorylation of RELA protein]; Acetylcysteine inhibits the reaction [ferrous sulfate affects the localization of RELA protein]; Acetylcysteine inhibits the reaction [Lipopolysaccharides affects the localization of RELA protein]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of RELA protein modified form]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of RELA protein]; Acetylcysteine inhibits the reaction [RELA protein binds to MMP9 promoter]; Acetylcysteine inhibits the reaction [Smoke affects the localization of RELA protein]; Acetylcysteine inhibits the reaction [TNF protein affects the localization of RELA protein]
[Acetylcysteine co-treated with oenothein B] results in decreased phosphorylation of RELA protein; [Acetylcysteine co-treated with TNF protein] results in decreased activity of RELA protein; Acetylcysteine affects the localization of and results in increased activity of RELA protein; Acetylcysteine affects the reaction [[manganese chloride results in increased abundance of Manganese] which affects the localization of RELA protein]; Acetylcysteine inhibits the reaction [2'-(4-chlorophenyl)-3-(4-chlorophenylidene)-5,10-dimethyl-12-methylene-decahydro-1,2-(1',3'-dioxocyclopenta(c))azuleno(4,5-b)furan-4,11-dione affects the localization of RELA protein]; Acetylcysteine inhibits the reaction [2'-(4-chlorophenyl)-3-(4-chlorophenylidene)-5,10-dimethyl-12-methylene-decahydro-1,2-(1',3'-dioxocyclopenta(c))azuleno(4,5-b)furan-4,11-dione results in decreased expression of RELA protein]; Acetylcysteine inhibits the reaction [2,3,5-trichloro-6-phenyl-(1,4)benzoquinone results in increased phosphorylation of RELA protein]; Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased phosphorylation of RELA protein]; Acetylcysteine inhibits the reaction [acenaphthenequinone results in increased expression of RELA protein]; Acetylcysteine inhibits the reaction [Acrolein promotes the reaction [Lipopolysaccharides results in increased phosphorylation of RELA protein]]; Acetylcysteine inhibits the reaction [Acrolein results in increased phosphorylation of RELA protein]; Acetylcysteine inhibits the reaction [APP protein affects the localization of RELA protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide affects the localization of RELA protein]; Acetylcysteine inhibits the reaction [benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased activity of RELA protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of RELA protein]; Acetylcysteine inhibits the reaction [Chloroquine results in increased activity of RELA protein]; Acetylcysteine inhibits the reaction [chrysin results in increased activity of RELA protein]; Acetylcysteine inhibits the reaction [cobaltous chloride results in increased phosphorylation of RELA protein]; Acetylcysteine inhibits the reaction [cryptotanshinone affects the localization of RELA protein]; Acetylcysteine inhibits the reaction [Fenbendazole analog results in increased phosphorylation of RELA protein]; Acetylcysteine inhibits the reaction [Fenbendazole results in increased phosphorylation of RELA protein]; Acetylcysteine inhibits the reaction [hydroquinone results in increased phosphorylation of RELA protein]; Acetylcysteine inhibits the reaction [hydroxyethyl methacrylate affects the localization of and results in decreased activity of RELA protein]; Acetylcysteine inhibits the reaction [IL1B promotes the reaction [EP300 protein binds to RELA protein]]; Acetylcysteine inhibits the reaction [IL1B protein results in increased expression of RELA protein modified form]; Acetylcysteine inhibits the reaction [Imatinib Mesylate results in increased phosphorylation of RELA protein]; Acetylcysteine inhibits the reaction [Lipopolysaccharides promotes the reaction [Acrolein results in increased phosphorylation of RELA protein]]; Acetylcysteine inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of RELA protein]; Acetylcysteine inhibits the reaction [mancozeb affects the localization of RELA protein]; Acetylcysteine inhibits the reaction [Nicotine results in increased expression of RELA protein]; Acetylcysteine inhibits the reaction [Nicotine results in increased phosphorylation of RELA protein]; Acetylcysteine inhibits the reaction [Norepinephrine affects the localization of RELA protein]; Acetylcysteine inhibits the reaction [Particulate Matter affects the localization of RELA protein]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased phosphorylation of RELA protein]; Acetylcysteine inhibits the reaction [saikosaponin D results in increased acetylation of RELA protein]; Acetylcysteine inhibits the reaction [sodium arsenite results in increased expression of RELA protein modified form]; Acetylcysteine inhibits the reaction [tert-butyl-2-(4,5-dihydrogen-4,4,5,5-tetramethyl-3-O-1H-imidazole-3-cationic-1-oxyl-2-pyrrolidine-1-carboxylic ester) affects the expression of RELA protein]; Acetylcysteine inhibits the reaction [titanium dioxide results in increased expression of RELA protein]; Acetylcysteine inhibits the reaction [TNF protein results in increased activity of RELA protein]
Acetylcysteine results in increased activity of RELA protein
Acetylcysteine results in increased glutathionylation of RELA protein

PMID:7491977 PMID:8760145 PMID:11970852 PMID:15139008 PMID:17925309 More...

NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484

G

RELB proto-oncogene, NF-kB subunit

multiple interactions

Acetylcysteine inhibits the reaction [Lipopolysaccharides affects the localization of RELB protein]
Acetylcysteine inhibits the reaction [Drugs, Chinese Herbal inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of RELB protein]]

PMID:11970852 PMID:19642688

NCBI chr 1:79,257,738...79,285,490
Ensembl chr 1:79,257,725...79,285,507

G

renin

multiple interactions

Acetylcysteine inhibits the reaction [ioxitalamic acid results in increased expression of REN protein]

NCBI chr13:44,796,260...44,807,491
Ensembl chr13:44,796,091...44,807,489

G

regulator of G-protein signaling 16

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of RGS16 mRNA

NCBI chr13:65,887,668...65,892,862
Ensembl chr13:65,887,530...65,892,857

G

regulator of G-protein signaling like 2 homolog (mouse)

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of RGSL2H mRNA

NCBI chr13:65,973,695...65,974,702

G

Rho-related BTB domain containing 1

decreases expression

Acetylcysteine results in decreased expression of RHOBTB1 mRNA

NCBI chr20:19,327,142...19,456,121
Ensembl chr20:19,327,155...19,403,012

G

receptor interacting serine/threonine kinase 1

multiple interactions

[Acetylcysteine results in decreased abundance of Reactive Oxygen Species] inhibits the reaction [Lipopolysaccharides promotes the reaction [Polystyrenes results in increased expression of RIPK1 mRNA]]; [Acetylcysteine results in decreased abundance of Reactive Oxygen Species] inhibits the reaction [Lipopolysaccharides promotes the reaction [Polystyrenes results in increased expression of RIPK1 protein]]; [Acetylcysteine results in decreased abundance of Reactive Oxygen Species] inhibits the reaction [Polystyrenes promotes the reaction [Lipopolysaccharides results in increased expression of RIPK1 mRNA]]; [Acetylcysteine results in decreased abundance of Reactive Oxygen Species] inhibits the reaction [Polystyrenes promotes the reaction [Lipopolysaccharides results in increased expression of RIPK1 protein]]; Acetylcysteine affects the reaction [Benzo(a)pyrene affects the expression of RIPK1 protein]; Acetylcysteine inhibits the reaction [tricalcium phosphate results in increased phosphorylation of RIPK1 protein]

PMID:35777681 PMID:35833596 PMID:37678662

NCBI chr17:30,839,639...30,871,824
Ensembl chr17:30,839,650...30,871,824

G

receptor-interacting serine-threonine kinase 2

multiple interactions

Acetylcysteine inhibits the reaction [Cholesterol analog results in increased expression of RIPK2 mRNA]

NCBI chr 5:29,630,806...29,662,804
Ensembl chr 5:29,631,570...29,662,657

G

receptor-interacting serine-threonine kinase 3

multiple interactions

[Acetylcysteine results in decreased abundance of Reactive Oxygen Species] inhibits the reaction [Lipopolysaccharides promotes the reaction [Polystyrenes results in increased expression of RIPK3 mRNA]]; [Acetylcysteine results in decreased abundance of Reactive Oxygen Species] inhibits the reaction [Lipopolysaccharides promotes the reaction [Polystyrenes results in increased expression of RIPK3 protein]]; [Acetylcysteine results in decreased abundance of Reactive Oxygen Species] inhibits the reaction [Polystyrenes promotes the reaction [Lipopolysaccharides results in increased expression of RIPK3 mRNA]]; [Acetylcysteine results in decreased abundance of Reactive Oxygen Species] inhibits the reaction [Polystyrenes promotes the reaction [Lipopolysaccharides results in increased expression of RIPK3 protein]]; Acetylcysteine affects the reaction [Benzo(a)pyrene affects the expression of RIPK3 protein]; Acetylcysteine inhibits the reaction [tricalcium phosphate results in increased phosphorylation of RIPK3 protein]
Acetylcysteine inhibits the reaction [1,3-dichloro-2-propanol results in increased expression of RIPK3 protein]

PMID:35777681 PMID:35833596 PMID:36000575 PMID:37678662

NCBI chr15:29,283,153...29,292,107
Ensembl chr15:29,283,145...29,292,121

G

ribonuclease A family member 2

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of RNASE2 mRNA

NCBI chr15:24,449,618...24,450,427
Ensembl chr15:24,449,611...24,450,479

G

ring finger protein 125

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of RNF125 mRNA

NCBI chr18:12,254,066...12,275,719
Ensembl chr18:12,253,852...12,275,983

G

RAR-related orphan receptor A

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of RORA mRNA

NCBI chr 8:69,301,635...70,034,741
Ensembl chr 8:69,301,733...70,025,931

G

ribosomal protein S6 kinase B1

multiple interactions

Acetylcysteine inhibits the reaction [arsenite results in increased phosphorylation of and results in increased activity of RPS6KB1 protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of RPS6KB1 protein]; Acetylcysteine inhibits the reaction [Chromium results in decreased phosphorylation of RPS6KB1 protein]; Acetylcysteine inhibits the reaction [Zearalenone results in decreased phosphorylation of RPS6KB1 protein]
Acetylcysteine inhibits the reaction [4-nonylphenol results in decreased phosphorylation of RPS6KB1 protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of RPS6KB1 protein]

PMID:14516795 PMID:18569013 PMID:21195169 PMID:24299490 PMID:26804764 More...

NCBI chr10:71,323,777...71,367,908
Ensembl chr10:71,323,777...71,367,908

G

receptor (chemosensory) transporter protein 1

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of RTP1 mRNA; Acetylcysteine inhibits the reaction [[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of RTP1 mRNA]

NCBI chr11:77,422,982...77,425,498
Ensembl chr11:77,422,982...77,425,498

G

RUNX family transcription factor 2

multiple interactions

Acetylcysteine inhibits the reaction [Cadmium Chloride results in decreased expression of RUNX2 mRNA]
Acetylcysteine inhibits the reaction [Dexamethasone affects the expression of RUNX2 mRNA]

PMID:19017541 PMID:24239970

NCBI chr 9:16,167,504...16,492,826
Ensembl chr 9:16,167,482...16,492,167

G

retinoid X receptor alpha

multiple interactions

Acetylcysteine inhibits the reaction [SOD2 protein affects the expression of RXRA mRNA]

NCBI chr 3:10,989,832...11,076,366
Ensembl chr 3:10,989,832...11,073,712

G

S100 calcium binding protein A11

multiple interactions

Acetylcysteine inhibits the reaction [[S100A11 mutant form results in increased susceptibility to Cisplatin] which results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [[S100A11 mutant form results in increased susceptibility to Cisplatin] which results in increased cleavage of CASP9 protein]; Acetylcysteine inhibits the reaction [[S100A11 mutant form results in increased susceptibility to Cisplatin] which results in increased cleavage of PARP1 protein]

NCBI chr 2:179,191,688...179,197,098
Ensembl chr 2:179,191,715...179,197,044

G

S100 calcium-binding protein A4

multiple interactions

Acetylcysteine inhibits the reaction [Dietary Fats results in increased expression of S100A4 mRNA]

NCBI chr 2:176,090,951...176,093,258
Ensembl chr 2:176,091,804...176,093,254

G

S100 calcium binding protein A9

multiple interactions

Acetylcysteine inhibits the reaction [Isoproterenol results in increased expression of S100A9 protein]

NCBI chr 2:176,190,361...176,193,182
Ensembl chr 2:176,190,361...176,193,230

G

spermidine/spermine N1-acetyl transferase 1

multiple interactions

Acetylcysteine inhibits the reaction [elesclomol results in increased expression of SAT1 mRNA]

NCBI chr X:40,158,354...40,161,641
Ensembl chr X:40,157,046...40,196,813

G

stearoyl-CoA desaturase

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of SCD1 mRNA

NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562

G

SEC31 homolog A, COPII coat complex component

multiple interactions

Acetylcysteine inhibits the reaction [Paraquat results in increased methylation of SEC31A mRNA]

NCBI chr14:9,214,324...9,269,281
Ensembl chr14:9,214,349...9,269,273

G

selectin E

decreases expression
multiple interactions

Acetylcysteine results in decreased expression of SELE mRNA
Acetylcysteine inhibits the reaction [tetrachlorobenzoquinone results in increased expression of SELE protein]
Acetylcysteine inhibits the reaction [Drugs, Chinese Herbal inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of SELE protein]]

PMID:16084531 PMID:19642688 PMID:26901245

NCBI chr13:76,402,841...76,412,741
Ensembl chr13:76,403,304...76,412,741

G

selenoprotein I

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of SELENOI mRNA

NCBI chr 6:26,073,127...26,111,326
Ensembl chr 6:26,072,648...26,111,314

G

serpin family H member 1

multiple interactions

Acetylcysteine inhibits the reaction [cobaltous chloride results in decreased expression of SERPINH1 mRNA]; Acetylcysteine inhibits the reaction [cobaltous chloride results in decreased expression of SERPINH1 protein]

NCBI chr 1:153,643,500...153,650,853
Ensembl chr 1:153,643,510...153,650,801

G

sestrin 2

multiple interactions

Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of SESN2 mRNA]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of SESN2 protein]; Acetylcysteine inhibits the reaction [erastin results in increased expression of SESN2 protein]; Acetylcysteine inhibits the reaction [Hemin results in increased expression of SESN2 protein]; Acetylcysteine inhibits the reaction [Quercetin results in increased expression of SESN2 protein]

PMID:24535669 PMID:29662624 PMID:31054940 PMID:31323261

NCBI chr 5:144,702,287...144,721,241
Ensembl chr 5:144,701,530...144,721,260

G

secreted frizzled-related protein 2

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of SFRP2 mRNA

NCBI chr 2:169,089,517...169,097,064
Ensembl chr 2:169,089,517...169,097,063

G

surfactant protein A1

multiple interactions

Acetylcysteine affects the reaction [Particulate Matter affects the expression of SFTPA1 protein]
Acetylcysteine inhibits the reaction [Silicon Dioxide results in decreased expression of SFTPA1 protein]

PMID:31449845 PMID:35689653

NCBI chr16:17,008,180...17,011,686
Ensembl chr16:17,008,180...17,011,685

G

surfactant protein B

multiple interactions
increases expression

Acetylcysteine inhibits the reaction [Silicon Dioxide results in decreased expression of SFTPB protein]
Acetylcysteine results in increased expression of SFTPB protein
Acetylcysteine inhibits the reaction [[Air Pollutants, Occupational results in increased abundance of Particulate Matter] which results in decreased expression of SFTPB protein]; Acetylcysteine inhibits the reaction [Particulate Matter results in decreased expression of SFTPB protein]

PMID:27208422 PMID:35689653

NCBI chr 4:104,359,303...104,368,439
Ensembl chr 4:104,359,396...104,368,436

G

surfactant protein C

increases expression
multiple interactions

Acetylcysteine results in increased expression of SFTPC protein
Acetylcysteine inhibits the reaction [[Air Pollutants, Occupational results in increased abundance of Particulate Matter] which results in decreased expression of SFTPC protein]; Acetylcysteine inhibits the reaction [Particulate Matter results in decreased expression of SFTPC protein]

NCBI chr15:45,596,565...45,599,615
Ensembl chr15:45,596,574...45,610,777

G

SHC adaptor protein 1

multiple interactions

Acetylcysteine inhibits the reaction [SHC1 protein results in decreased expression of CDH1 protein]; Acetylcysteine inhibits the reaction [SHC1 protein results in increased expression of VIM protein]
Acetylcysteine inhibits the reaction [sodium arsenite results in increased expression of and results in increased phosphorylation of SHC1 protein]
Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased expression of and results in increased phosphorylation of SHC1 protein]; Acetylcysteine inhibits the reaction [sodium arsenite results in increased expression of and results in increased phosphorylation of SHC1 protein]

PMID:32659284 PMID:33360347

NCBI chr 2:174,837,937...174,849,538
Ensembl chr 2:174,837,930...174,849,536

G

shisa family member 2

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of SHISA2 mRNA

NCBI chr15:33,806,715...33,811,013
Ensembl chr15:33,805,958...33,811,013

G

sirtuin 1

multiple interactions

Acetylcysteine inhibits the reaction [antimony trichloride results in decreased expression of SIRT1 mRNA]; Acetylcysteine inhibits the reaction [antimony trichloride results in decreased expression of SIRT1 protein]; Acetylcysteine inhibits the reaction [Glucose results in decreased expression of SIRT1 protein]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in decreased expression of SIRT1 protein]; Acetylcysteine inhibits the reaction [sodium arsenite results in decreased expression of SIRT1 protein]
Acetylcysteine inhibits the reaction [Cadmium Chloride results in decreased expression of SIRT1 protein]; Acetylcysteine inhibits the reaction [sodium arsenite results in decreased expression of SIRT1 protein]

PMID:21031461 PMID:30055241 PMID:33360347 PMID:36493885

NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260

G

sirtuin 3

multiple interactions

Acetylcysteine inhibits the reaction [bisphenol A results in decreased expression of SIRT3 protein]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in decreased expression of SIRT3 mRNA]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in decreased expression of SIRT3 protein]
Acetylcysteine inhibits the reaction [Antimycin A results in increased expression of SIRT3 mRNA]

PMID:30104959 PMID:30641872 PMID:35430258

NCBI chr 1:195,942,066...195,964,472
Ensembl chr 1:195,942,073...195,964,808

G

Src-like-adaptor 2

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of SLA2 mRNA

NCBI chr 3:145,367,070...145,383,586
Ensembl chr 3:145,368,598...145,382,480

G

solute carrier family 12 member 1

increases expression

Acetylcysteine results in increased expression of SLC12A1 protein

NCBI chr 3:112,406,140...112,482,913
Ensembl chr 3:112,406,140...112,482,899

G

solute carrier family 12 member 3

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of SLC12A3 mRNA

NCBI chr19:10,630,651...10,679,250
Ensembl chr19:10,631,393...10,669,091

G

solute carrier family 14 member 2

multiple interactions
increases expression

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of SLC14A2 mRNA
Acetylcysteine results in increased expression of SLC14A2 protein

PMID:22129741 PMID:23183129

NCBI chr18:71,612,460...72,039,462
Ensembl chr18:71,612,460...71,792,968

G

solute carrier family 19 member 2

multiple interactions

Acetylcysteine inhibits the reaction [elesclomol results in increased expression of SLC19A2 mRNA]

NCBI chr13:76,601,975...76,616,175
Ensembl chr13:76,601,900...76,616,172

G

solute carrier family 1 member 1

multiple interactions

Acetylcysteine affects the reaction [SLC1A1 protein affects the transport of Zinc]; Acetylcysteine inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine affects the localization of SLC1A1 protein]; Acetylcysteine inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine affects the metabolism of SLC1A1 protein]

PMID:18093171 PMID:22575539

NCBI chr 1:226,549,932...226,631,925
Ensembl chr 1:226,549,842...226,630,402

G

solute carrier family 1 member 2

multiple interactions

Acetylcysteine inhibits the reaction [cobaltous chloride results in decreased expression of SLC1A2 protein]; Acetylcysteine inhibits the reaction [Cocaine results in decreased expression of SLC1A2 protein]
Acetylcysteine inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in decreased expression of SLC1A2 mRNA]; Acetylcysteine inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in decreased expression of SLC1A2 protein]

PMID:19717140 PMID:22895544 PMID:34310962

NCBI chr 3:89,005,129...89,135,469
Ensembl chr 3:89,005,129...89,126,498

G

solute carrier family 22, member 17

multiple interactions

Acetylcysteine inhibits the reaction [sodium arsenite results in decreased expression of SLC22A17 mRNA]

NCBI chr15:28,382,285...28,389,435
Ensembl chr15:28,382,292...28,388,799

G

solute carrier family 22, member 24

multiple interactions

Acetylcysteine inhibits the reaction [Cisplatin results in increased expression of SLC22A24 protein]

NCBI chr 1:204,910,450...204,965,538
Ensembl chr 1:204,910,455...204,965,538

G

solute carrier family 22 member 4

multiple interactions

Acetylcysteine inhibits the reaction [Mercury results in decreased activity of SLC22A4 protein]; Acetylcysteine inhibits the reaction [methylmercuric chloride results in decreased activity of SLC22A4 protein]

NCBI chr10:38,133,333...38,179,932
Ensembl chr10:38,133,322...38,179,720

G

solute carrier family 22 member 5

multiple interactions

Acetylcysteine affects the reaction [Methylmercury Compounds results in decreased transport of SLC22A5 protein]; Acetylcysteine inhibits the reaction [Mercuric Chloride results in decreased transport of SLC22A5 protein]

NCBI chr10:38,008,303...38,035,474
Ensembl chr10:38,008,311...38,035,309

G

solute carrier family 22 member 6

multiple interactions

adipic acid inhibits the reaction [SLC22A6 protein results in increased susceptibility to [mercuric oxide co-treated with Acetylcysteine]]; Glutarates inhibits the reaction [SLC22A6 protein results in increased uptake of [mercuric oxide co-treated with Acetylcysteine]]; Ketoglutaric Acids inhibits the reaction [SLC22A6 protein results in increased susceptibility to [mercuric oxide co-treated with Acetylcysteine]]; p-Aminohippuric Acid inhibits the reaction [SLC22A6 protein results in increased susceptibility to [mercuric oxide co-treated with Acetylcysteine]]; Probenecid inhibits the reaction [SLC22A6 protein results in increased susceptibility to [mercuric oxide co-treated with Acetylcysteine]]; Probenecid inhibits the reaction [SLC22A6 protein results in increased uptake of [mercuric oxide co-treated with Acetylcysteine]]; SLC22A6 protein results in increased susceptibility to [mercuric oxide co-treated with Acetylcysteine]; SLC22A6 protein results in increased transport of [Acetylcysteine co-treated with Mercury]; SLC22A6 protein results in increased transport of [Acetylcysteine co-treated with Methylmercury Compounds]; SLC22A6 protein results in increased uptake of [mercuric oxide co-treated with Acetylcysteine]

PMID:12606766 PMID:15908511

NCBI chr 1:205,522,579...205,531,179
Ensembl chr 1:205,522,729...205,531,173

G

solute carrier family 22 member 8

multiple interactions

SLC22A8 protein results in increased uptake of [mercuric oxide co-treated with Acetylcysteine]

NCBI chr 1:205,496,331...205,516,378
Ensembl chr 1:205,498,084...205,517,450

G

solute carrier family 24 member 2

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of SLC24A2 mRNA

NCBI chr 5:101,497,916...101,741,840
Ensembl chr 5:101,502,278...101,739,337

G

solute carrier family 25 member 20

multiple interactions

Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in decreased activity of SLC25A20 protein]
Acetylcysteine inhibits the reaction [Mercuric Chloride results in decreased activity of SLC25A20 protein]; Acetylcysteine inhibits the reaction [methylmercuric chloride results in decreased activity of SLC25A20 protein]

PMID:23402788 PMID:25849418

NCBI chr 8:109,365,056...109,386,512
Ensembl chr 8:109,365,002...109,386,512

G

solute carrier family 25, member 47

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of SLC25A47 mRNA

NCBI chr 6:127,767,365...127,773,000
Ensembl chr 6:127,767,305...127,773,005

G

solute carrier family 27 member 2

multiple interactions

[Acetylcysteine co-treated with Dietary Fats] results in increased expression of SLC27A2 mRNA

NCBI chr 3:113,804,728...113,842,208
Ensembl chr 3:113,804,728...113,842,208

G

solute carrier family 2 member 1

multiple interactions

Acetylcysteine inhibits the reaction [2,3',4,4',5-pentachlorobiphenyl results in increased expression of SLC2A1 mRNA]; Acetylcysteine inhibits the reaction [2,4,5,2',4',5'-hexachlorobiphenyl results in increased expression of SLC2A1 mRNA]; Acetylcysteine inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SLC2A1 mRNA]; Acetylcysteine inhibits the reaction [DDT results in increased expression of SLC2A1 mRNA]

PMID:30821169 PMID:31251971 PMID:31724279

NCBI chr 5:132,717,196...132,745,416
Ensembl chr 5:132,717,196...132,745,416

G

solute carrier family 2 member 2

multiple interactions

Acetylcysteine inhibits the reaction [Pyruvaldehyde affects the localization of SLC2A2 protein]

NCBI chr 2:111,609,798...111,639,930
Ensembl chr 2:111,611,774...111,639,933

G

solute carrier family 2 member 3

multiple interactions

Acetylcysteine inhibits the reaction [epigallocatechin gallate results in increased expression of SLC2A3 mRNA]; Acetylcysteine inhibits the reaction [epigallocatechin gallate results in increased expression of SLC2A3 protein]

NCBI chr 4:155,960,944...156,026,000
Ensembl chr 4:155,960,946...156,025,472

G

solute carrier family 2 member 4

multiple interactions

Acetylcysteine inhibits the reaction [INS1 protein results in increased expression of SLC2A4 protein]

NCBI chr10:54,666,015...54,671,581
Ensembl chr10:54,666,015...54,671,565

G

solute carrier family 30 member 1

multiple interactions

Acetylcysteine inhibits the reaction [elesclomol results in increased expression of SLC30A1 mRNA]

NCBI chr13:103,491,037...103,494,910
Ensembl chr13:103,491,037...103,494,910

G

solute carrier family 35 member D2

multiple interactions

Acetylcysteine inhibits the reaction [Tobacco Smoke Pollution results in increased expression of SLC35D2 mRNA]

NCBI chr17:987,899...1,019,747
Ensembl chr17:988,157...1,019,743

G

solute carrier family 38, member 2

multiple interactions

Acetylcysteine inhibits the reaction [arsenite results in increased expression of SLC38A2 mRNA]

NCBI chr 7:127,851,267...127,863,482
Ensembl chr 7:127,851,267...127,863,436

G

solute carrier family 39 member 14

increases expression

Acetylcysteine results in increased expression of SLC39A14 mRNA

NCBI chr15:45,376,806...45,423,549
Ensembl chr15:45,376,917...45,423,524

G

solute carrier family 40 member 1

multiple interactions

Acetylcysteine inhibits the reaction [Cadmium results in increased expression of SLC40A1 mRNA]

NCBI chr 9:48,033,526...48,053,876
Ensembl chr 9:48,033,526...48,051,481

G

solute carrier family 4 member 1 (Diego blood group)

multiple interactions

[Acetylcysteine co-treated with Atorvastatin] inhibits the reaction [sodium arsenite affects the localization of SLC4A1 protein]

NCBI chr10:87,306,865...87,323,132
Ensembl chr10:87,306,872...87,323,117

G

solute carrier family 5 member 5

multiple interactions

Acetylcysteine inhibits the reaction [bisphenol A results in decreased expression of SLC5A5 mRNA]

NCBI chr16:18,546,709...18,556,698
Ensembl chr16:18,546,709...18,556,697

G

solute carrier family 6 member 6

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of SLC6A6 mRNA

NCBI chr 4:124,195,186...124,268,880
Ensembl chr 4:124,195,218...124,268,875

G

solute carrier family 7 member 11

multiple interactions

Acetylcysteine inhibits the reaction [Cocaine results in decreased expression of SLC7A11 protein]
Acetylcysteine inhibits the reaction [elesclomol results in increased expression of SLC7A11 mRNA]

PMID:18723479 PMID:19717140

NCBI chr 2:134,382,002...134,517,622
Ensembl chr 2:133,963,107...134,517,536

G

solute carrier family 7, member 14

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of SLC7A14 mRNA

NCBI chr 2:112,065,286...112,171,319
Ensembl chr 2:112,065,286...112,171,313

G

SMAD family member 1

decreases phosphorylation

Acetylcysteine results in decreased phosphorylation of SMAD1 protein

NCBI chr19:28,513,130...28,573,665
Ensembl chr19:28,513,131...28,573,651

G

SMAD family member 2

multiple interactions
decreases phosphorylation

Acetylcysteine inhibits the reaction [[Cadmium Chloride co-treated with sodium arsenite] results in increased expression of SMAD2 mRNA]; Acetylcysteine inhibits the reaction [TGFB1 protein results in increased phosphorylation of SMAD2 protein]; Acetylcysteine inhibits the reaction [Water Pollutants, Chemical results in increased expression of SMAD2 mRNA]
Acetylcysteine results in decreased phosphorylation of SMAD2 protein

PMID:29408318 PMID:30317545 PMID:32947957

NCBI chr18:69,849,884...69,918,926
Ensembl chr18:69,850,377...69,912,323

G

SMAD family member 3

multiple interactions
decreases phosphorylation

[Acetylcysteine co-treated with Cadmium Chloride co-treated with sodium arsenite] results in decreased expression of SMAD3 mRNA; [Acetylcysteine co-treated with Cadmium] results in decreased expression of SMAD3 mRNA; [Acetylcysteine co-treated with Water Pollutants, Chemical] results in decreased expression of SMAD3 mRNA; Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased phosphorylation of SMAD3 protein]; Acetylcysteine inhibits the reaction [TGFB1 protein results in increased phosphorylation of SMAD3 protein]
Acetylcysteine results in decreased phosphorylation of SMAD3 protein

PMID:21131394 PMID:29408318 PMID:30317545 PMID:34687772

NCBI chr 8:64,126,829...64,236,960
Ensembl chr 8:64,110,039...64,236,960

G

structural maintenance of chromosomes 1A

multiple interactions

Acetylcysteine inhibits the reaction [Doxorubicin promotes the reaction [ATM protein results in increased phosphorylation of SMC1A protein]]; Acetylcysteine inhibits the reaction [resveratrol results in increased phosphorylation of SMC1A protein]

PMID:15489221 PMID:24933654

NCBI chr X:21,103,323...21,148,053
Ensembl chr X:21,103,282...21,148,056

G

snail family transcriptional repressor 1

multiple interactions
decreases expression

Acetylcysteine inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of SNAI1 mRNA]; Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of SNAI1 protein]; Acetylcysteine inhibits the reaction [Aldosterone results in increased expression of SNAI1 mRNA]; Acetylcysteine inhibits the reaction [benz(a)anthracene results in increased expression of SNAI1 mRNA]; Acetylcysteine inhibits the reaction [benzo(k)fluoranthene results in increased expression of SNAI1 mRNA]; Acetylcysteine inhibits the reaction [di-n-propyldithiocarbamate results in decreased expression of SNAI1 protein]; Acetylcysteine inhibits the reaction [indeno(1,2,3-cd)pyrene results in increased expression of SNAI1 mRNA]
Acetylcysteine results in decreased expression of SNAI1 protein

PMID:17596522 PMID:21635667 PMID:28284859 PMID:32687844 PMID:34687772

NCBI chr 3:156,248,479...156,252,969
Ensembl chr 3:156,248,485...156,252,969

G

snail family transcriptional repressor 2

multiple interactions

Acetylcysteine inhibits the reaction [di-n-propyldithiocarbamate results in decreased expression of SNAI2 protein]

NCBI chr11:86,182,788...86,186,203
Ensembl chr11:86,181,909...86,186,200

G

synuclein alpha

multiple interactions

Acetylcysteine inhibits the reaction [1,2,3,4-tetrahydro-1-(phenylmethyl)isoquinoline results in increased expression of SNCA protein]
Acetylcysteine inhibits the reaction [Cadmium results in increased expression of SNCA mRNA]; Acetylcysteine inhibits the reaction [Lead results in increased expression of SNCA mRNA]; Acetylcysteine inhibits the reaction [Silicon Dioxide analog results in increased expression of SNCA protein]

PMID:15114628 PMID:27613482 PMID:34816377

NCBI chr 4:89,696,420...89,797,240
Ensembl chr 4:89,696,420...89,796,262

G

syntrophin, gamma 1

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of SNTG1 mRNA

NCBI chr 5:9,980,550...10,794,666
Ensembl chr 5:9,981,115...10,791,181

G

superoxide dismutase 1

multiple interactions
decreases expression
increases activity

Acetylcysteine inhibits the reaction [1-Methyl-4-phenylpyridinium results in decreased activity of SOD1 protein]; Acetylcysteine inhibits the reaction [[EGF co-treated with Colforsin co-treated with Rotenone] results in increased expression of SOD1 mRNA]; Acetylcysteine inhibits the reaction [[EGF co-treated with Colforsin co-treated with Rotenone] results in increased expression of SOD1 protein]; Acetylcysteine inhibits the reaction [[Hydrogen Peroxide co-treated with Nitroprusside] results in decreased expression of SOD1 protein]; Acetylcysteine inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] which results in increased expression of SOD1 protein]; Acetylcysteine inhibits the reaction [bisphenol A results in increased expression of SOD1 mRNA]; Acetylcysteine inhibits the reaction [Glucose deficiency results in increased degradation of SOD1 protein]; Acetylcysteine inhibits the reaction [manumycin results in decreased expression of SOD1]; Acetylcysteine inhibits the reaction [Polystyrenes analog results in increased expression of SOD1 protein]; Acetylcysteine inhibits the reaction [Rotenone results in increased expression of SOD1 mRNA]; Acetylcysteine inhibits the reaction [Rotenone results in increased expression of SOD1 protein]; Acetylcysteine promotes the reaction [Eugenol results in decreased expression of SOD1 mRNA]
Acetylcysteine inhibits the reaction [Cadmium results in decreased expression of SOD1 mRNA]; Acetylcysteine inhibits the reaction [Chlorpyrifos results in decreased expression of SOD1 protein]; Acetylcysteine inhibits the reaction [Diclofenac results in decreased activity of SOD1 protein]; Acetylcysteine inhibits the reaction [Lead results in decreased expression of SOD1 mRNA]; Acetylcysteine inhibits the reaction [methylmercuric chloride results in decreased expression of SOD1 protein]
[Acetylcysteine co-treated with Thapsigargin] results in decreased expression of SOD1 mRNA; Acetylcysteine inhibits the reaction [Cadmium Chloride results in decreased activity of SOD1 protein]; Acetylcysteine inhibits the reaction [Cadmium results in increased expression of SOD1 protein]; Acetylcysteine inhibits the reaction [Diethylhexyl Phthalate results in decreased activity of SOD1 protein]; Acetylcysteine inhibits the reaction [Diethylhexyl Phthalate results in decreased expression of SOD1 mRNA]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in decreased activity of SOD1 protein]; Acetylcysteine inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of SOD1 protein]; Acetylcysteine inhibits the reaction [perfluorooctanoic acid results in increased expression of SOD1 mRNA]
Acetylcysteine results in decreased expression of SOD1 mRNA
Acetylcysteine results in increased activity of SOD1 protein

PMID:16101137 PMID:17309078 PMID:19264484 PMID:19409983 PMID:20674559 More...

NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249

G

superoxide dismutase 2

multiple interactions
increases expression

[Acetylcysteine results in increased expression of SOD2 protein] which results in decreased abundance of Reactive Oxygen Species; Acetylcysteine inhibits the reaction [Cadmium results in increased expression of SOD2 protein]; Acetylcysteine inhibits the reaction [Cyclosporine results in decreased expression of SOD2 protein]; Acetylcysteine inhibits the reaction [Sodium Chloride results in increased expression of SOD2 protein]; Acetylcysteine inhibits the reaction [Streptozocin results in decreased expression of SOD2 protein]; Acetylcysteine promotes the reaction [Oxygen results in increased expression of SOD2 mRNA]; Acetylcysteine promotes the reaction [Oxygen results in increased expression of SOD2 protein]
Acetylcysteine inhibits the reaction [Atorvastatin results in increased expression of SOD2 mRNA]; Acetylcysteine inhibits the reaction [bisphenol A results in increased acetylation of SOD2 protein]; Acetylcysteine inhibits the reaction [Chlorpyrifos results in decreased expression of SOD2 protein]; Acetylcysteine inhibits the reaction [Glucose results in decreased expression of SOD2 mRNA]; Acetylcysteine inhibits the reaction [Glucose results in decreased expression of SOD2 protein]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in decreased activity of SOD2 protein]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased acetylation of SOD2 protein]; Acetylcysteine inhibits the reaction [Monocrotophos results in decreased expression of SOD2 mRNA]
Acetylcysteine results in increased expression of SOD2 mRNA; Acetylcysteine results in increased expression of SOD2 protein
[Acetylcysteine co-treated with IL1A protein] results in increased expression of SOD2 protein; [Acetylcysteine co-treated with TNF protein] results in increased expression of SOD2 protein; [Acetylcysteine results in decreased abundance of Reactive Oxygen Species] which results in decreased expression of SOD2 mRNA; Acetylcysteine affects the reaction [SOD2 protein affects the activity of CASP9 protein]; Acetylcysteine affects the reaction [SOD2 protein results in decreased susceptibility to Doxorubicin]; Acetylcysteine affects the reaction [SOD2 protein results in decreased susceptibility to Paclitaxel]; Acetylcysteine inhibits the reaction [[[15-deoxyprostaglandin J2 results in increased activity of PPARG protein] which results in decreased expression of SOD2 protein] which results in increased abundance of Reactive Oxygen Species]; Acetylcysteine inhibits the reaction [[EGF co-treated with Colforsin co-treated with Rotenone] results in increased expression of SOD2 mRNA]; Acetylcysteine inhibits the reaction [[EGF co-treated with Colforsin co-treated with Rotenone] results in increased expression of SOD2 protein]; Acetylcysteine inhibits the reaction [[Hydrogen Peroxide co-treated with Nitroprusside] results in increased expression of SOD2 protein]; Acetylcysteine inhibits the reaction [Antimycin A results in increased expression of SOD2 mRNA]; Acetylcysteine inhibits the reaction [Arachidonic Acid results in increased expression of SOD2 mRNA]; Acetylcysteine inhibits the reaction [Arachidonic Acid results in increased expression of SOD2 protein]; Acetylcysteine inhibits the reaction [bisphenol A results in increased expression of SOD2 mRNA]; Acetylcysteine inhibits the reaction [Glucose deficiency affects the folding of SOD2 protein]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased expression of SOD2 mRNA]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased expression of SOD2 protein]; Acetylcysteine inhibits the reaction [linsidomine results in increased expression of SOD2 mRNA]; Acetylcysteine inhibits the reaction [N-acetylsphingosine results in increased expression of SOD2 mRNA]; Acetylcysteine inhibits the reaction [N-acetylsphingosine results in increased expression of SOD2 protein]; Acetylcysteine inhibits the reaction [Norepinephrine results in increased expression of SOD2 mRNA]; Acetylcysteine inhibits the reaction [Peroxynitrous Acid results in increased expression of SOD2 mRNA]; Acetylcysteine inhibits the reaction [Rotenone results in increased expression of and results in increased activity of SOD2 protein]; Acetylcysteine inhibits the reaction [Rotenone results in increased expression of SOD2 mRNA]; Acetylcysteine inhibits the reaction [Rotenone results in increased expression of SOD2 protein]; Acetylcysteine inhibits the reaction [SOD2 protein affects the activity of AR protein]; Acetylcysteine inhibits the reaction [SOD2 protein affects the expression of AKR1C3 mRNA]; Acetylcysteine inhibits the reaction [SOD2 protein affects the expression of AMACR mRNA]; Acetylcysteine inhibits the reaction [SOD2 protein affects the expression of ESR1 mRNA]; Acetylcysteine inhibits the reaction [SOD2 protein affects the expression of ESR2 mRNA]; Acetylcysteine inhibits the reaction [SOD2 protein affects the expression of FKBP5 mRNA]; Acetylcysteine inhibits the reaction [SOD2 protein affects the expression of HSD11B2 mRNA]; Acetylcysteine inhibits the reaction [SOD2 protein affects the expression of HSD17B8 mRNA]; Acetylcysteine inhibits the reaction [SOD2 protein affects the expression of KLK3 mRNA]; Acetylcysteine inhibits the reaction [SOD2 protein affects the expression of PGR mRNA]; Acetylcysteine inhibits the reaction [SOD2 protein affects the expression of RXRA mRNA]; Acetylcysteine inhibits the reaction [SOD2 protein affects the expression of TMPRSS2 mRNA]; Acetylcysteine inhibits the reaction [SOD2 protein affects the expression of VEGFA mRNA]; Acetylcysteine inhibits the reaction [TGFB1 protein results in decreased expression of SOD2 mRNA]; Acetylcysteine inhibits the reaction [TNF protein results in increased expression of SOD2 mRNA]; Acetylcysteine inhibits the reaction [TNF protein results in increased expression of SOD2 protein]; Acetylcysteine inhibits the reaction [TNF protein results in increased expression of SOD2]; Acetylcysteine promotes the reaction [Eugenol results in decreased expression of SOD2 mRNA]; Acetylcysteine promotes the reaction [IL1A protein results in increased expression of SOD2 mRNA]; Acetylcysteine promotes the reaction [TNF protein results in increased expression of SOD2 mRNA]; TNF protein promotes the reaction [Acetylcysteine results in increased expression of SOD2 mRNA]

PMID:7476933 PMID:8760145 PMID:9535218 PMID:9741582 PMID:11264281 More...

NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189

G

superoxide dismutase 3

multiple interactions

Acetylcysteine inhibits the reaction [cobaltous chloride results in decreased expression of SOD3 mRNA]; Acetylcysteine inhibits the reaction [Doxorubicin results in decreased expression of SOD3 protein]

PMID:21804221 PMID:34358621

NCBI chr14:58,610,104...58,615,845
Ensembl chr14:58,609,958...58,615,990

G

sorbitol dehydrogenase

multiple interactions

Acetylcysteine inhibits the reaction [Diclofenac results in increased secretion of SORD protein]

NCBI chr 3:109,184,697...109,216,133
Ensembl chr 3:109,184,676...109,216,133

G

SRY-box transcription factor 17

multiple interactions

N-acetyl-cysteine inhibits the reaction [angiotensin II decreases expression of SOX17 protein in retinal endothelial cells]

RGD

NCBI chr 5:15,016,660...15,022,228
Ensembl chr 5:15,016,731...15,022,228

G

Sp1 transcription factor

multiple interactions
decreases expression

Acetylcysteine inhibits the reaction [Camptothecin results in increased expression of SP1 mRNA]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in decreased expression of SP1 protein]; Acetylcysteine inhibits the reaction [sodium arsenite results in decreased expression of SP1 protein]; Acetylcysteine inhibits the reaction [Sodium Selenite results in decreased expression of SP1 protein]
Acetylcysteine results in decreased expression of SP1 protein

PMID:16928829 PMID:18556457 PMID:30851366 PMID:33360347

NCBI chr 7:133,541,302...133,571,961
Ensembl chr 7:133,541,491...133,571,961

G

sphingosine kinase 1

multiple interactions

Acetylcysteine inhibits the reaction [Glucose results in increased expression of and results in increased activity of SPHK1 protein]

NCBI chr10:101,758,567...101,764,240
Ensembl chr10:101,758,711...101,764,240

G

Spi-1 proto-oncogene

multiple interactions

Acetylcysteine inhibits the reaction [3-phenoxybenzoic acid inhibits the reaction [Tretinoin results in increased expression of SPI1 mRNA]]; Acetylcysteine inhibits the reaction [cypermethrin inhibits the reaction [Tretinoin results in increased expression of SPI1 mRNA]]

NCBI chr 3:77,059,744...77,093,730
Ensembl chr 3:77,073,012...77,092,393

G

SPARC/osteonectin, cwcv and kazal like domains proteoglycan 2

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of SPOCK2 mRNA

NCBI chr20:28,037,334...28,064,272
Ensembl chr20:28,033,475...28,064,272

G

secreted phosphoprotein 1

multiple interactions

Acetylcysteine inhibits the reaction [Allylamine results in increased expression of SPP1 mRNA]; Acetylcysteine inhibits the reaction [cobaltous chloride results in increased expression of SPP1 protein]

PMID:15910882 PMID:19356721

NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162

G

sequestosome 1

multiple interactions
increases expression

Acetylcysteine affects the reaction [sodium arsenite affects the expression of SQSTM1 protein]; Acetylcysteine inhibits the reaction [4-hydroxy-2-nonenal results in increased expression of SQSTM1 mRNA]; Acetylcysteine inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] which results in increased expression of SQSTM1 mRNA]; Acetylcysteine inhibits the reaction [Acrolein results in decreased expression of SQSTM1 protein]; Acetylcysteine inhibits the reaction [brazilin results in decreased expression of SQSTM1 protein]; Acetylcysteine inhibits the reaction [cucurbitacin E results in increased expression of SQSTM1 protein]; Acetylcysteine inhibits the reaction [di-2-pyridylketone-4,4-dimethyl-3-thiosemicarbazone results in increased expression of SQSTM1 protein]; Acetylcysteine inhibits the reaction [Doxorubicin results in decreased expression of SQSTM1 protein]; Acetylcysteine inhibits the reaction [Doxorubicin results in increased degradation of SQSTM1 protein]; Acetylcysteine inhibits the reaction [ovatodiolide results in increased expression of SQSTM1 protein]; Acetylcysteine inhibits the reaction [Patulin results in decreased expression of SQSTM1 protein]; Acetylcysteine inhibits the reaction [Potassium Iodide results in increased expression of SQSTM1 mRNA]; Acetylcysteine inhibits the reaction [Potassium Iodide results in increased expression of SQSTM1 protein]; Acetylcysteine inhibits the reaction [pyrovalerone analog results in decreased expression of SQSTM1 protein]; Acetylcysteine inhibits the reaction [tri-o-cresyl phosphate results in increased expression of SQSTM1 protein]
Acetylcysteine results in increased expression of SQSTM1 protein
Acetylcysteine inhibits the reaction [[Aluminum Chloride results in increased abundance of Aluminum] which results in decreased expression of SQSTM1 mRNA]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in decreased expression of SQSTM1 protein]; Acetylcysteine inhibits the reaction [chromium hexavalent ion results in decreased expression of SQSTM1 protein]; Acetylcysteine inhibits the reaction [cupric chloride results in increased expression of SQSTM1 protein]; Acetylcysteine inhibits the reaction [tricalcium phosphate results in decreased expression of SQSTM1 protein]
Acetylcysteine inhibits the reaction [decamethrin results in increased expression of SQSTM1 protein]; Acetylcysteine promotes the reaction [manganese chloride results in increased expression of SQSTM1 protein]

PMID:22927544 PMID:25301941 PMID:26588882 PMID:27106530 PMID:28063998 More...

NCBI chr10:34,525,517...34,536,670
Ensembl chr10:34,525,519...34,536,673

G

SRC proto-oncogene, non-receptor tyrosine kinase

multiple interactions

Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased phosphorylation of SRC protein]; Acetylcysteine inhibits the reaction [Silicon Dioxide results in increased phosphorylation of SRC protein]; Acetylcysteine inhibits the reaction [thymoquinone results in decreased phosphorylation of SRC protein]
N-acetyl-L-cysteine inhibits the reaction [apigenin-7-O-gentiobioside decreases phosphorylation of SRC protein in the stomach)

CTD
RGD

PMID:21777978 PMID:29894800 PMID:31433961 PMID:29408335

NCBI chr 3:146,091,969...146,139,492
Ensembl chr 3:146,091,841...146,139,476

G

src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of SRMS mRNA

NCBI chr 3:168,318,511...168,324,915
Ensembl chr 3:168,318,512...168,324,915

G

sulfiredoxin 1

multiple interactions

[Acetylcysteine affects the abundance of Reactive Oxygen Species] inhibits the reaction [Cadmium Chloride results in increased expression of SRXN1 mRNA]; [Acetylcysteine affects the abundance of Reactive Oxygen Species] inhibits the reaction [Copper Sulfate results in increased expression of SRXN1 mRNA]; [Acetylcysteine affects the abundance of Reactive Oxygen Species] inhibits the reaction [diethyl maleate results in increased expression of SRXN1 mRNA]; [Acetylcysteine affects the abundance of Reactive Oxygen Species] inhibits the reaction [Methyl Methanesulfonate results in increased expression of SRXN1 mRNA]; [Acetylcysteine affects the abundance of Reactive Oxygen Species] inhibits the reaction [sodium arsenite results in increased expression of SRXN1 mRNA]

NCBI chr 3:140,604,490...140,610,050
Ensembl chr 3:140,599,608...140,628,448

G

steroidogenic acute regulatory protein

multiple interactions

Acetylcysteine inhibits the reaction [Dimethoate results in decreased expression of STAR mRNA]; Acetylcysteine inhibits the reaction [nickel sulfate results in decreased expression of STAR mRNA]; Acetylcysteine inhibits the reaction [nickel sulfate results in decreased expression of STAR protein]
Acetylcysteine inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of STAR protein]; Acetylcysteine inhibits the reaction [Polystyrenes analog results in decreased expression of STAR mRNA]; Acetylcysteine inhibits the reaction [Polystyrenes analog results in decreased expression of STAR protein]
Acetylcysteine inhibits the reaction [anacetrapib results in increased expression of STAR mRNA]; Acetylcysteine inhibits the reaction [dalcetrapib results in increased expression of STAR mRNA]; Acetylcysteine inhibits the reaction [torcetrapib results in increased expression of STAR mRNA]

PMID:25617244 PMID:26769589 PMID:29567110 PMID:30648648 PMID:36709824

NCBI chr16:66,267,094...66,274,368
Ensembl chr16:66,264,807...66,271,672

G

signal transducer and activator of transcription 1

multiple interactions

Acetylcysteine inhibits the reaction [Mercuric Chloride inhibits the reaction [CNTF protein results in increased phosphorylation of STAT1 protein]]; Acetylcysteine inhibits the reaction [nickel sulfate results in increased phosphorylation of STAT1 protein]; Acetylcysteine inhibits the reaction [Ozone results in increased phosphorylation of STAT1 protein]
Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of STAT1 protein]
Acetylcysteine inhibits the reaction [15-deoxy-delta(12,14)-prostaglandin J2 inhibits the reaction [IFNG protein results in increased phosphorylation of STAT1 protein]]; Acetylcysteine promotes the reaction [IFNG protein results in increased phosphorylation of STAT1 protein]

PMID:12847270 PMID:16896058 PMID:17607690 PMID:19061877 PMID:20525893

NCBI chr 9:49,419,561...49,459,969
Ensembl chr 9:49,419,340...49,588,540

G

signal transducer and activator of transcription 3

multiple interactions
treatment
decreases phosphorylation

Acetylcysteine inhibits the reaction [1,2,5,8-tetrahydroxy anthraquinone results in decreased phosphorylation of STAT3 protein]; Acetylcysteine inhibits the reaction [1,4-naphthoquinone analog results in decreased phosphorylation of STAT3 protein]; Acetylcysteine inhibits the reaction [2'-(4-chlorophenyl)-3-(4-chlorophenylidene)-5,10-dimethyl-12-methylene-decahydro-1,2-(1',3'-dioxocyclopenta(c))azuleno(4,5-b)furan-4,11-dione results in decreased phosphorylation of STAT3 protein]; Acetylcysteine inhibits the reaction [27-hydroxycholesterol results in increased phosphorylation of STAT3 protein]; Acetylcysteine inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of STAT3 protein modified form]; Acetylcysteine inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of STAT3 protein]; Acetylcysteine inhibits the reaction [Arsenic analog results in increased phosphorylation of STAT3 protein]; Acetylcysteine inhibits the reaction [DDT results in increased phosphorylation of and results in increased expression of STAT3 protein]; Acetylcysteine inhibits the reaction [manumycin results in decreased phosphorylation of STAT3 protein]; Acetylcysteine inhibits the reaction [Mercuric Chloride inhibits the reaction [CNTF protein results in increased phosphorylation of STAT3 protein]]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased phosphorylation of STAT3 protein]; Acetylcysteine inhibits the reaction [Silicon Dioxide results in increased phosphorylation of and results in increased activity of STAT3 protein]; Acetylcysteine inhibits the reaction [thymoquinone results in decreased phosphorylation of and results in decreased activity of STAT3 protein]; Acetylcysteine inhibits the reaction [thymoquinone results in decreased phosphorylation of STAT3 protein]; Acetylcysteine inhibits the reaction [TNF protein results in increased phosphorylation of STAT3 protein]
N-acetyl-L-cysteine co-treated with Il-6 inhibits the reaction [apigenin-7-O-gentiobioside decreases phosphorylation of STAT3 protein in the stomach)
Acetylcysteine results in decreased phosphorylation of STAT3 protein
Acetylcysteine inhibits the reaction [Streptozocin results in decreased phosphorylation of STAT3 protein]; Allopurinol promotes the reaction [Acetylcysteine inhibits the reaction [Streptozocin results in decreased phosphorylation of STAT3 protein]]
Acetylcysteine inhibits the reaction [27-hydroxycholesterol results in increased phosphorylation of STAT3 protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of STAT3 mRNA]; Acetylcysteine inhibits the reaction [NSC 680410 results in decreased phosphorylation of STAT3 protein]; Acetylcysteine inhibits the reaction [Paraquat results in increased methylation of STAT3 mRNA]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased phosphorylation of STAT3 protein]

CTD
RGD

PMID:16481037 PMID:16896058 PMID:17666914 PMID:19409983 PMID:21741372 More...

NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057

G

small ubiquitin-like modifier 1

multiple interactions

Acetylcysteine inhibits the reaction [Acetaminophen results in increased expression of SUMO1 mRNA]

NCBI chr 9:61,078,790...61,108,697
Ensembl chr 9:61,077,435...61,108,761

G

synapsin I

multiple interactions

Acetylcysteine inhibits the reaction [Particulate Matter results in decreased expression of SYN1 mRNA]; Acetylcysteine inhibits the reaction [Particulate Matter results in decreased expression of SYN1 protein]

PMID:27624276 PMID:28153600

NCBI chr X:1,172,208...1,227,400
Ensembl chr X:1,172,208...1,227,396

G

synaptophysin

multiple interactions

Acetylcysteine inhibits the reaction [Streptozocin results in decreased expression of SYP protein]

NCBI chr X:14,849,444...14,864,553
Ensembl chr X:14,849,444...14,864,745

G

synaptotagmin 7

multiple interactions

[Acetylcysteine co-treated with Dexamethasone] results in decreased expression of SYT7 mRNA

NCBI chr 1:207,031,359...207,093,787
Ensembl chr 1:207,031,592...207,089,026

G

TGF-beta activated kinase 1/MAP3K7 binding protein 2

decreases binding

N-acetyl-cysteine inhibits binding of Traf6 protein to Tab2 in rat neonatal cardiomyocytes

RGD

NCBI chr 1:2,375,026...2,425,115
Ensembl chr 1:2,375,490...2,424,756

G

transaldolase 1

multiple interactions

Acetylcysteine inhibits the reaction [TALDO1 gene mutant form results in decreased abundance of Glutathione]; Acetylcysteine inhibits the reaction [TALDO1 gene mutant form results in decreased abundance of NADP]; Acetylcysteine inhibits the reaction [TALDO1 gene mutant form results in decreased abundance of Nitric Oxide]; Acetylcysteine inhibits the reaction [TALDO1 gene mutant form results in decreased phosphorylation of CTNNB1 protein]

NCBI chr 1:196,493,634...196,503,965
Ensembl chr 1:196,493,589...196,503,974

G

TRAF family member-associated NFKB activator

decreases expression

Acetylcysteine results in decreased expression of TANK mRNA

NCBI chr 3:46,114,230...46,190,270
Ensembl chr 3:46,114,274...46,190,264

G

TAR DNA binding protein

multiple interactions

Acetylcysteine inhibits the reaction [arsenite promotes the reaction [TARDBP protein binds to PPP1R15A protein]]

NCBI chr 5:159,050,518...159,062,218
Ensembl chr 5:159,051,799...159,062,055

G

taste receptor, type 2, member 108

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of TAS2R108 mRNA

NCBI chr 4:69,287,667...69,288,581
Ensembl chr 4:69,287,667...69,288,581

G

telomerase reverse transcriptase

multiple interactions
increases expression

Acetylcysteine inhibits the reaction [Camptothecin results in increased expression of TERT protein]; Acetylcysteine inhibits the reaction [manumycin results in decreased expression of TERT protein]
Acetylcysteine results in increased expression of TERT protein
Acetylcysteine inhibits the reaction [arsenic trioxide results in decreased activity of TERT protein]; Acetylcysteine inhibits the reaction [monomethylarsonous acid results in decreased activity of TERT protein]

PMID:18336854 PMID:19409983 PMID:30851366

NCBI chr 1:29,637,213...29,659,561
Ensembl chr 1:29,637,506...29,659,561

G

tet methylcytosine dioxygenase 1

multiple interactions
increases expression

Acetylcysteine inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] promotes the reaction [TET1 protein binds to CDKN2A promoter]]; Acetylcysteine inhibits the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] which results in increased expression of TET1 protein]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of TET1 mRNA]
[[Cadmium Chloride results in increased abundance of Cadmium] which co-treated with Acetylcysteine] results in decreased expression of TET1 mRNA; Acetylcysteine inhibits the reaction [[[Cadmium Chloride results in increased abundance of Cadmium] which co-treated with hydroquinone] results in decreased expression of TET1 mRNA]; Acetylcysteine inhibits the reaction [hydroquinone results in decreased expression of TET1 mRNA]
Acetylcysteine results in increased expression of TET1 mRNA

PMID:28153600 PMID:31551408 PMID:33188856

NCBI chr20:25,761,042...25,840,926
Ensembl chr20:25,768,120...25,833,052

G

tet methylcytosine dioxygenase 2

multiple interactions

Acetylcysteine inhibits the reaction [dorsomorphin results in decreased expression of TET2 protein]

NCBI chr 2:221,988,645...222,072,813
Ensembl chr 2:221,988,645...222,072,534

G

transcription factor A, mitochondrial

multiple interactions

Acetylcysteine inhibits the reaction [Atorvastatin results in increased expression of TFAM mRNA]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in decreased expression of TFAM mRNA]; Acetylcysteine inhibits the reaction [Monocrotophos results in decreased expression of TFAM mRNA]; Acetylcysteine inhibits the reaction [sodium bisulfite results in decreased expression of TFAM mRNA]
Acetylcysteine inhibits the reaction [2-chloroethyl ethyl sulfide results in decreased expression of TFAM mRNA]; Acetylcysteine inhibits the reaction [dimethoxyethyl phthalate results in decreased expression of TFAM protein]

PMID:21775390 PMID:26980303 PMID:32142722 PMID:34214916 PMID:35403558 More...

NCBI chr20:17,356,243...17,368,293
Ensembl chr20:17,356,197...17,368,292

G

transcription factor binding to IGHM enhancer 3

multiple interactions

Acetylcysteine inhibits the reaction [Glycochenodeoxycholic Acid results in decreased expression of TFE3 mRNA]; Acetylcysteine inhibits the reaction [sodium arsenite results in decreased phosphorylation of and affects the localization of TFE3 protein]

PMID:29945972 PMID:32439580

NCBI chr X:14,729,547...14,742,830
Ensembl chr X:14,729,550...14,742,571

G

transcription factor EB

multiple interactions

Acetylcysteine inhibits the reaction [4-hydroxy-2-nonenal affects the localization of TFEB protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide affects the localization of TFEB protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of TFEB mRNA]; Acetylcysteine inhibits the reaction [sodium arsenite results in decreased phosphorylation of TFEB protein]

PMID:29307831 PMID:29945972 PMID:33462182 PMID:35550146

NCBI chr 9:13,198,890...13,254,726
Ensembl chr 9:13,198,891...13,254,714

G

transferrin receptor

multiple interactions

Acetylcysteine inhibits the reaction [Zinc deficiency results in increased expression of TFRC protein]

NCBI chr11:68,163,413...68,185,257
Ensembl chr11:68,163,413...68,185,257

G

transforming growth factor alpha

multiple interactions

Acetylcysteine inhibits the reaction [Nitrofurazone results in increased expression of TGFA mRNA]

NCBI chr 4:118,618,043...118,700,897
Ensembl chr 4:118,618,269...118,700,894

G

transforming growth factor, beta 1

multiple interactions
decreases expression

Acetylcysteine inhibits the reaction [Paraquat results in increased expression of TGFB1 mRNA]; Acetylcysteine inhibits the reaction [titanium dioxide results in increased expression of TGFB1 mRNA]
Acetylcysteine results in decreased expression of TGFB1 mRNA; Acetylcysteine results in decreased expression of TGFB1 protein modified form
Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of TGFB1 mRNA]; Acetylcysteine inhibits the reaction [Glucose results in increased expression of TGFB1 mRNA]; Acetylcysteine inhibits the reaction [Glucose results in increased expression of TGFB1 protein]
Acetylcysteine inhibits the reaction [4-cresol sulfate results in increased expression of and results in increased secretion of TGFB1 protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased secretion of TGFB1 protein]; Acetylcysteine inhibits the reaction [TGFB1 protein results in decreased expression of CAT mRNA]; Acetylcysteine inhibits the reaction [TGFB1 protein results in decreased expression of SOD2 mRNA]; Acetylcysteine inhibits the reaction [TGFB1 protein results in increased abundance of Reactive Oxygen Species]; Acetylcysteine inhibits the reaction [TGFB1 protein results in increased expression of ACTA2 protein]; Acetylcysteine inhibits the reaction [TGFB1 protein results in increased expression of HGF protein]; Acetylcysteine inhibits the reaction [TGFB1 protein results in increased expression of IL6 protein]; Acetylcysteine inhibits the reaction [TGFB1 protein results in increased expression of NOX4 mRNA]; Acetylcysteine inhibits the reaction [TGFB1 protein results in increased expression of VEGFA protein]; Acetylcysteine inhibits the reaction [TGFB1 protein results in increased phosphorylation of SMAD2 protein]; Acetylcysteine inhibits the reaction [TGFB1 protein results in increased phosphorylation of SMAD3 protein]; Acetylcysteine inhibits the reaction [TGFB1 protein results in increased secretion of IL6 protein]

PMID:16757516 PMID:21131394 PMID:21765237 PMID:23159718 PMID:23325087 More...

NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847

G

transforming growth factor beta 1 induced transcript 1

multiple interactions

Acetylcysteine inhibits the reaction [Ethylmercury Compounds results in increased expression of TGFB1I1 mRNA]

NCBI chr 1:182,828,553...182,835,465
Ensembl chr 1:182,828,544...182,837,080

G

transforming growth factor, beta 3

multiple interactions

[Acetylcysteine co-treated with Cadmium] results in decreased expression of TGFB3 mRNA; Acetylcysteine inhibits the reaction [[Cadmium Chloride co-treated with sodium arsenite] results in increased expression of and results in increased secretion of TGFB3 protein]; Acetylcysteine inhibits the reaction [[Cadmium Chloride co-treated with sodium arsenite] results in increased expression of TGFB3 mRNA]; Acetylcysteine inhibits the reaction [Cadmium results in increased expression of and results in increased secretion of TGFB3 protein]; Acetylcysteine inhibits the reaction [Water Pollutants, Chemical results in increased expression of and results in increased secretion of TGFB3 protein]; Acetylcysteine inhibits the reaction [Water Pollutants, Chemical results in increased expression of TGFB3 mRNA]

NCBI chr 6:105,704,058...105,726,661
Ensembl chr 6:105,704,236...105,726,564

G

transforming growth factor, beta receptor 1

decreases expression
multiple interactions

Acetylcysteine results in decreased expression of TGFBR1 mRNA; Acetylcysteine results in decreased expression of TGFBR1 protein
[Acetylcysteine co-treated with Cadmium] results in decreased expression of TGFBR1 mRNA; Acetylcysteine inhibits the reaction [[Cadmium Chloride co-treated with sodium arsenite] results in increased expression of TGFBR1 mRNA]; Acetylcysteine inhibits the reaction [Water Pollutants, Chemical results in increased expression of TGFBR1 mRNA]
Buthionine Sulfoximine inhibits the reaction [Acetylcysteine results in decreased expression of TGFBR1 mRNA]; Buthionine Sulfoximine inhibits the reaction [Acetylcysteine results in decreased expression of TGFBR1 protein]

PMID:17602960 PMID:29408318

NCBI chr 5:61,653,773...61,710,777
Ensembl chr 5:61,653,233...61,710,777

G

transforming growth factor, beta receptor 2

decreases expression
multiple interactions

Acetylcysteine results in decreased expression of TGFBR2 mRNA; Acetylcysteine results in decreased expression of TGFBR2 protein
Buthionine Sulfoximine inhibits the reaction [Acetylcysteine results in decreased expression of TGFBR2 mRNA]; Buthionine Sulfoximine inhibits the reaction [Acetylcysteine results in decreased expression of TGFBR2 protein]

NCBI chr 8:115,794,537...115,883,615
Ensembl chr 8:115,794,537...115,883,228

G

transglutaminase 1

multiple interactions

Acetylcysteine inhibits the reaction [Particulate Matter analog results in decreased activity of TGM1 protein]; Acetylcysteine inhibits the reaction [Vehicle Emissions analog results in decreased activity of TGM1 protein]

NCBI chr15:29,191,039...29,206,000
Ensembl chr15:29,191,041...29,204,523

G

transglutaminase 2

multiple interactions

Acetylcysteine inhibits the reaction [Particulate Matter analog results in decreased activity of TGM2 protein]; Acetylcysteine inhibits the reaction [Vehicle Emissions analog results in decreased activity of TGM2 protein]

NCBI chr 3:146,772,684...146,801,924
Ensembl chr 3:146,772,687...146,801,981

G

tyrosine hydroxylase

multiple interactions
decreases expression

[Ascorbic Acid co-treated with alpha-Tocopherol co-treated with Acetylcysteine] results in decreased expression of TH protein; Acetylcysteine inhibits the reaction [Chlorpyrifos results in decreased expression of TH protein]
Acetylcysteine results in decreased expression of TH protein

PMID:22714038 PMID:25891525

NCBI chr 1:198,071,500...198,078,832
Ensembl chr 1:198,071,503...198,109,767

G

thrombospondin 1

multiple interactions

Acetylcysteine inhibits the reaction [cobaltous chloride results in decreased expression of TSP1 mRNA]

NCBI chr 3:105,056,293...105,071,445
Ensembl chr 3:105,056,292...105,071,440

G

thrombopoietin

multiple interactions

Acetylcysteine inhibits the reaction [THPO protein results in increased abundance of Reactive Oxygen Species]; Acetylcysteine inhibits the reaction [THPO protein results in increased expression of GP1BA protein]; Acetylcysteine inhibits the reaction [THPO protein results in increased expression of ITGA2B protein]; Acetylcysteine inhibits the reaction [THPO protein results in increased expression of ITGB3 protein]

Ensembl chr11:80,182,820...80,188,167

G

TIMP metallopeptidase inhibitor 2

multiple interactions

Acetylcysteine inhibits the reaction [[[Cadmium Chloride results in increased abundance of Cadmium] which co-treated with hydroquinone] results in decreased expression of TIMP2 mRNA]; Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of TIMP2 mRNA]

NCBI chr10:103,541,199...103,590,611
Ensembl chr10:103,531,505...103,590,611

G

TIMP metallopeptidase inhibitor 3

increases expression
multiple interactions

Acetylcysteine results in increased expression of TIMP3 mRNA
Acetylcysteine inhibits the reaction [[[Cadmium Chloride results in increased abundance of Cadmium] which co-treated with hydroquinone] results in decreased expression of TIMP3 mRNA]; Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of TIMP3 mRNA]; Acetylcysteine inhibits the reaction [hydroquinone results in decreased expression of TIMP3 mRNA]

NCBI chr 7:17,520,827...17,571,850
Ensembl chr 7:17,521,919...17,571,839

G

tight junction protein 1

multiple interactions

Acetylcysteine inhibits the reaction [Glyphosate results in decreased expression of TJP1 protein]; Acetylcysteine inhibits the reaction [tributyltin results in decreased expression of TJP1 protein]
Acetylcysteine inhibits the reaction [Particulate Matter results in decreased expression of TJP1 protein]
Acetylcysteine inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of TJP1 mRNA]; Acetylcysteine inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in decreased expression of TJP1 protein]; Acetylcysteine inhibits the reaction [bisphenol A results in decreased expression of TJP1 mRNA]; Acetylcysteine inhibits the reaction [Glucose results in decreased expression of TJP1 protein]

PMID:26079211 PMID:27783111 PMID:29235125 PMID:32687961 PMID:33485121 More...

NCBI chr 1:118,849,838...119,094,492
Ensembl chr 1:118,849,838...119,094,432

G

tight junction protein 2

multiple interactions

Acetylcysteine inhibits the reaction [Glucose results in decreased expression of TJP2 protein]

NCBI chr 1:221,709,745...221,838,291
Ensembl chr 1:221,709,745...221,838,295

G

toll-like receptor 2

decreases expression

Acetylcysteine results in decreased expression of TLR2 mRNA

NCBI chr 2:169,200,620...169,206,819
Ensembl chr 2:169,197,419...169,206,630

G

toll-like receptor 4

multiple interactions
decreases expression

Acetylcysteine inhibits the reaction [4-hydroxy-2-nonenal inhibits the reaction [Lipopolysaccharides promotes the reaction [TLR4 protein binds to TLR4 protein]]]; Acetylcysteine inhibits the reaction [4-hydroxy-2-nonenal inhibits the reaction [Lipopolysaccharides results in increased activity of TLR4 protein]]; Acetylcysteine inhibits the reaction [benzanthrone results in increased expression of TLR4 protein]; Acetylcysteine inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of TLR4 mRNA]
Acetylcysteine inhibits the reaction [Acrolein promotes the reaction [Lipopolysaccharides results in increased expression of TLR4 protein]]; Acetylcysteine inhibits the reaction [Acrolein results in increased expression of TLR4 protein]
Acetylcysteine results in decreased expression of TLR4 mRNA

PMID:19627980 PMID:22385246 PMID:28495615 PMID:36055550 PMID:37369159

NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628

G

transmembrane protein 140

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of TMEM140 mRNA

NCBI chr 4:63,536,477...63,547,478
Ensembl chr 4:63,536,168...63,548,455

G

tenascin C

decreases expression

Acetylcysteine results in decreased expression of TNC mRNA

NCBI chr 5:77,375,851...77,460,712
Ensembl chr 5:77,375,851...77,460,624

G

tumor necrosis factor

decreases expression
multiple interactions
affects expression

Acetylcysteine results in decreased expression of TNF mRNA; Acetylcysteine results in decreased expression of TNF protein
[Acetylcysteine co-treated with TNF protein] results in decreased activity of RELA protein; [Acetylcysteine co-treated with TNF protein] results in increased expression of SOD2 protein; Acetylcysteine inhibits the reaction [2,3,5-trichloro-6-phenyl-(1,4)benzoquinone results in increased expression of TNF protein]; Acetylcysteine inhibits the reaction [2,4-decadienal results in increased expression of and results in increased secretion of TNF protein]; Acetylcysteine inhibits the reaction [[cholix toxin, Vibrio cholerae co-treated with TNF protein] results in increased activity of CASP7 protein]; Acetylcysteine inhibits the reaction [[cholix toxin, Vibrio cholerae co-treated with TNF protein] results in increased activity of CASP8 protein]; Acetylcysteine inhibits the reaction [[cholix toxin, Vibrio cholerae co-treated with TNF protein] results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased secretion of TNF protein]; Acetylcysteine inhibits the reaction [[sodium arsenite co-treated with TNF protein] results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [[TNF protein co-treated with Diclofenac] results in increased activity of CASP8 protein]; Acetylcysteine inhibits the reaction [[TNF protein co-treated with Diclofenac] results in increased activity of CASP9 protein]; Acetylcysteine inhibits the reaction [Acetaminophen results in increased expression of TNF mRNA]; Acetylcysteine inhibits the reaction [Acrolein promotes the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]]; Acetylcysteine inhibits the reaction [Acrolein results in increased expression of TNF mRNA]; Acetylcysteine inhibits the reaction [Buthionine Sulfoximine results in increased secretion of TNF protein]; Acetylcysteine inhibits the reaction [butylphen results in increased expression of TNF protein]; Acetylcysteine inhibits the reaction [Chlorpyrifos results in increased expression of TNF protein]; Acetylcysteine inhibits the reaction [Dimethyl Fumarate inhibits the reaction [TNF protein results in increased expression of CCL2 mRNA]]; Acetylcysteine inhibits the reaction [Dimethyl Fumarate inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA]]; Acetylcysteine inhibits the reaction [Dimethyl Fumarate inhibits the reaction [TNF protein results in increased expression of TNF mRNA]]; Acetylcysteine inhibits the reaction [hydroquinone results in increased expression of TNF protein]; Acetylcysteine inhibits the reaction [Lipopolysaccharides promotes the reaction [Acrolein results in increased expression of TNF mRNA]]; Acetylcysteine inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; Acetylcysteine inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]; Acetylcysteine inhibits the reaction [Mimosine results in decreased activity of TNF protein]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of TNF mRNA]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of TNF protein]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased secretion of TNF protein]; Acetylcysteine inhibits the reaction [piperlongumine analog inhibits the reaction [TNF protein results in increased degradation of NFKBIA protein]]; Acetylcysteine inhibits the reaction [sodium arsenite results in increased expression of TNF mRNA]; Acetylcysteine inhibits the reaction [sodium arsenite results in increased expression of TNF protein]; Acetylcysteine inhibits the reaction [tert-Butylhydroperoxide results in increased secretion of TNF protein]; Acetylcysteine inhibits the reaction [TNF protein results in decreased abundance of Glutathione]; Acetylcysteine inhibits the reaction [TNF protein results in increased abundance of Hydrogen Peroxide]; Acetylcysteine inhibits the reaction [TNF protein results in increased abundance of Reactive Oxygen Species]; Acetylcysteine inhibits the reaction [TNF protein results in increased abundance of Superoxides]; Acetylcysteine inhibits the reaction [TNF protein results in increased activity of RELA protein]; Acetylcysteine inhibits the reaction [TNF protein results in increased cleavage of and results in increased activity of CASP1 protein]; Acetylcysteine inhibits the reaction [TNF protein results in increased expression of and results in increased secretion of FN1 protein]; Acetylcysteine inhibits the reaction [TNF protein results in increased expression of CCL5 protein]; Acetylcysteine inhibits the reaction [TNF protein results in increased expression of FN1 mRNA]; Acetylcysteine inhibits the reaction [TNF protein results in increased expression of ICAM1 protein]; Acetylcysteine inhibits the reaction [TNF protein results in increased expression of SOD2 mRNA]; Acetylcysteine inhibits the reaction [TNF protein results in increased expression of SOD2 protein]; Acetylcysteine inhibits the reaction [TNF protein results in increased expression of SOD2]; Acetylcysteine inhibits the reaction [TNF protein results in increased expression of TP53 mRNA]; Acetylcysteine inhibits the reaction [TNF protein results in increased expression of TP53 protein]; Acetylcysteine inhibits the reaction [TNF protein results in increased expression of VCAM1 protein]; Acetylcysteine inhibits the reaction [TNF protein results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [TNF protein results in increased phosphorylation of MAPK14 protein]; Acetylcysteine inhibits the reaction [TNF protein results in increased phosphorylation of MAPK3 protein]; Acetylcysteine inhibits the reaction [TNF protein results in increased phosphorylation of STAT3 protein]; Acetylcysteine inhibits the reaction [TNF protein results in increased secretion of IL1B protein]; Acetylcysteine inhibits the reaction [TNF results in decreased expression of NOS3 protein]; Acetylcysteine inhibits the reaction [TNF results in increased abundance of Malondialdehyde]; Acetylcysteine inhibits the reaction [TNF results in increased abundance of Nitric Oxide]; Acetylcysteine inhibits the reaction [Vehicle Emissions results in increased expression of TNF mRNA]; Acetylcysteine inhibits the reaction [Vehicle Emissions results in increased expression of TNF protein]; Acetylcysteine promotes the reaction [PIK3R1 protein modified form inhibits the reaction [butylphen results in increased expression of TNF protein]]; Acetylcysteine promotes the reaction [PIK3R1 protein modified form inhibits the reaction [hydroquinone results in increased expression of TNF protein]]; Acetylcysteine promotes the reaction [TNF protein results in increased expression of SOD2 mRNA]; TNF protein promotes the reaction [Acetylcysteine results in increased expression of SOD2 mRNA]
[Acetylcysteine results in decreased abundance of Reactive Oxygen Species] inhibits the reaction [Lipopolysaccharides promotes the reaction [Polystyrenes results in increased expression of TNF mRNA]]; [Acetylcysteine results in decreased abundance of Reactive Oxygen Species] inhibits the reaction [Lipopolysaccharides promotes the reaction [Polystyrenes results in increased expression of TNF protein]]; [Acetylcysteine results in decreased abundance of Reactive Oxygen Species] inhibits the reaction [Polystyrenes promotes the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]]; [Acetylcysteine results in decreased abundance of Reactive Oxygen Species] inhibits the reaction [Polystyrenes promotes the reaction [Lipopolysaccharides results in increased expression of TNF protein]]; Acetylcysteine inhibits the reaction [2-chloroethyl ethyl sulfide results in increased expression of TNF mRNA]; Acetylcysteine inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of TNF mRNA]; Acetylcysteine inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of TNF protein]; Acetylcysteine inhibits the reaction [[Air Pollutants results in increased abundance of Particulate Matter] which results in increased expression of TNF protein]; Acetylcysteine inhibits the reaction [[Potassium Dichromate results in increased abundance of chromium hexavalent ion] which results in increased expression of TNF protein]; Acetylcysteine inhibits the reaction [Acetaminophen results in increased expression of TNF protein]; Acetylcysteine inhibits the reaction [azoxystrobin inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of TNF mRNA]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of TNF protein]; Acetylcysteine inhibits the reaction [cobaltous chloride results in increased expression of TNF protein]; Acetylcysteine inhibits the reaction [Fungal Polysaccharides results in increased secretion of TNF protein]; Acetylcysteine inhibits the reaction [iprodione inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]]; Acetylcysteine inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; Acetylcysteine inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]; Acetylcysteine inhibits the reaction [manganese chloride promotes the reaction [Lipopolysaccharides results in increased expression of TNF protein]]; Acetylcysteine inhibits the reaction [Mercuric Chloride results in increased expression of TNF mRNA]; Acetylcysteine inhibits the reaction [Mimosine results in decreased activity of TNF protein]; Acetylcysteine inhibits the reaction [Nicotine results in increased expression of TNF mRNA]; Acetylcysteine inhibits the reaction [Nicotine results in increased secretion of TNF protein]; Acetylcysteine inhibits the reaction [NOX4 protein promotes the reaction [[Lipopolysaccharides co-treated with IFNG1 protein] results in increased expression of TNF protein]]; Acetylcysteine inhibits the reaction [Oxygen deficiency results in increased expression of TNF mRNA]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased secretion of TNF protein]; Acetylcysteine inhibits the reaction [Platelet Activating Factor results in increased expression of TNF mRNA]; Acetylcysteine inhibits the reaction [PRKAA2 protein affects the reaction [[Air Pollutants results in increased abundance of Particulate Matter] which results in increased expression of TNF protein]]; Acetylcysteine inhibits the reaction [titanium dioxide results in increased expression of TNF mRNA]; Acetylcysteine inhibits the reaction [TNF protein results in increased expression of CCL5 mRNA]; Acetylcysteine inhibits the reaction [TNF protein results in increased expression of CXCL1 mRNA]; Acetylcysteine inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA]; Acetylcysteine inhibits the reaction [TNF protein results in increased expression of MADCAM1 protein]; Acetylcysteine inhibits the reaction [TNF protein results in increased phosphorylation of RELA protein]; MYD88 protein affects the reaction [Acetylcysteine inhibits the reaction [Particulate Matter results in increased secretion of TNF protein]]; MYD88 protein affects the reaction [Polymyxin B promotes the reaction [Acetylcysteine inhibits the reaction [Particulate Matter results in increased secretion of TNF protein]]]; Polymyxin B promotes the reaction [Acetylcysteine inhibits the reaction [Particulate Matter results in increased secretion of TNF protein]]
Acetylcysteine affects the expression of TNF protein
Acetylcysteine analog inhibits the reaction [2-chloroethyl ethyl sulfide results in increased expression of TNF protein]; Acetylcysteine analog inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein]; Acetylcysteine inhibits the reaction [[Buthionine Sulfoximine co-treated with Lipopolysaccharides] results in increased secretion of TNF protein]; Acetylcysteine inhibits the reaction [[Paraquat co-treated with Maneb] results in increased expression of TNF mRNA]; Acetylcysteine inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of TNF protein]; Acetylcysteine inhibits the reaction [Acrylamide results in increased expression of TNF protein]; Acetylcysteine inhibits the reaction [Acrylonitrile results in increased expression of TNF mRNA]; Acetylcysteine inhibits the reaction [Buthionine Sulfoximine results in increased secretion of TNF protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of TNF mRNA]; Acetylcysteine inhibits the reaction [Cholesterol analog results in increased expression of TNF mRNA]; Acetylcysteine inhibits the reaction [cupric chloride results in increased secretion of TNF protein]; Acetylcysteine inhibits the reaction [cypermethrin results in increased expression of TNF protein]; Acetylcysteine inhibits the reaction [Diclofenac results in increased expression of TNF mRNA]; Acetylcysteine inhibits the reaction [Diclofenac results in increased expression of TNF protein]; Acetylcysteine inhibits the reaction [Fenitrothion results in increased expression of TNF protein]; Acetylcysteine inhibits the reaction [Fenitrothion results in increased secretion of TNF protein]; Acetylcysteine inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of TNF protein]; Acetylcysteine inhibits the reaction [Lipopolysaccharides results in increased secretion of TNF protein]; Acetylcysteine inhibits the reaction [Nicotine results in increased expression of TNF protein]; Acetylcysteine inhibits the reaction [Nitric Oxide deficiency results in increased expression of TNF protein]; Acetylcysteine inhibits the reaction [Nitrofurazone results in increased expression of TNF mRNA]; Acetylcysteine inhibits the reaction [Norepinephrine results in increased secretion of TNF protein]; Acetylcysteine inhibits the reaction [Palmitates results in increased expression of TNF mRNA]; Acetylcysteine inhibits the reaction [Palmitates results in increased expression of TNF protein]; Acetylcysteine inhibits the reaction [Palmitic Acid results in increased expression of TNF mRNA]; Acetylcysteine inhibits the reaction [Paraquat results in increased expression of TNF mRNA]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of TNF protein]; Acetylcysteine inhibits the reaction [Silicon Dioxide results in increased expression of TNF protein]; Acetylcysteine inhibits the reaction [Streptozocin results in increased expression of TNF protein]; Acetylcysteine inhibits the reaction [TNF protein affects the localization of RELA protein]; Acetylcysteine inhibits the reaction [TNF protein results in decreased phosphorylation of PTK2B protein]; Acetylcysteine inhibits the reaction [TNF protein results in increased abundance of Reactive Oxygen Species]; Acetylcysteine inhibits the reaction [TNF protein results in increased expression of and results in increased secretion of MMP9 protein]; Acetylcysteine inhibits the reaction [TNF protein results in increased expression of MMP9 mRNA]; Acetylcysteine inhibits the reaction [TNF protein results in increased expression of NOS2 protein]; Acetylcysteine inhibits the reaction [TNF protein results in increased phosphorylation of MAPK1 protein]; Acetylcysteine inhibits the reaction [TNF protein results in increased phosphorylation of MAPK3 protein]; Acetylcysteine promotes the reaction [caryophyllene inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of TNF protein]]; Acetylcysteine promotes the reaction [Doxorubicin results in increased expression of TNF mRNA]

PMID:7476933 PMID:7532384 PMID:8760145 PMID:9535218 PMID:9721806 More...

NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629

G

TNF alpha induced protein 3

multiple interactions

Acetylcysteine inhibits the reaction [Tobacco Smoke Pollution results in increased expression of TNFAIP3 mRNA]

NCBI chr 1:13,709,211...13,724,291
Ensembl chr 1:13,709,206...13,725,282

G

TNF alpha induced protein 6

multiple interactions

Acetylcysteine inhibits the reaction [LHB protein results in increased abundance of TNFAIP6 mRNA]

NCBI chr 3:36,502,250...36,521,652
Ensembl chr 3:36,502,188...36,521,649

G

TNF receptor superfamily member 10b

multiple interactions

Acetylcysteine inhibits the reaction [2'-(4-chlorophenyl)-3-(4-chlorophenylidene)-5,10-dimethyl-12-methylene-decahydro-1,2-(1',3'-dioxocyclopenta(c))azuleno(4,5-b)furan-4,11-dione results in increased expression of TNFRSF10A protein]; Acetylcysteine inhibits the reaction [ilimaquinone results in increased expression of TNFRSF10A mRNA]; Acetylcysteine inhibits the reaction [pendulone results in increased expression of TNFRSF10A protein]

PMID:21741372 PMID:24930757 PMID:35288263

NCBI chr15:44,840,386...44,868,318
Ensembl chr15:44,840,386...44,867,467

G

TNF receptor superfamily member 13C

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of TNFRSF13C mRNA

NCBI chr 7:113,736,046...113,738,523
Ensembl chr 7:113,736,055...113,738,517

G

TNF receptor superfamily member 1A

multiple interactions

Acetylcysteine inhibits the reaction [2'-(4-chlorophenyl)-3-(4-chlorophenylidene)-5,10-dimethyl-12-methylene-decahydro-1,2-(1',3'-dioxocyclopenta(c))azuleno(4,5-b)furan-4,11-dione results in decreased expression of TNFRSF1A protein]; Acetylcysteine inhibits the reaction [Mimosine results in increased cleavage of TNFRSF1A protein]

PMID:15550384 PMID:21741372

NCBI chr 4:158,150,815...158,163,592
Ensembl chr 4:158,150,820...158,163,591

G

TNF receptor superfamily member 1B

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of TNFRSF1B mRNA

NCBI chr 5:157,070,642...157,104,216
Ensembl chr 5:157,070,642...157,104,206

G

tumor necrosis factor receptor superfamily, member 22

multiple interactions

Acetylcysteine inhibits the reaction [tetrachlorobenzoquinone results in increased expression of TNFRSF10B mRNA]; Acetylcysteine inhibits the reaction [tetrachlorobenzoquinone results in increased expression of TNFRSF10B protein]

NCBI chr 1:198,840,452...198,860,713
Ensembl chr 1:198,840,453...198,856,309

G

TNF superfamily member 10

decreases expression
decreases response to substance
multiple interactions

Acetylcysteine results in decreased expression of TNFSF10 mRNA
Acetylcysteine results in decreased susceptibility to TNFSF10 protein
Acetylcysteine inhibits the reaction [[CSC-3436 co-treated with TNFSF10 protein] results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [[TNFSF10 protein co-treated with gingerol] results in increased cleavage of CASP3 protein]; Acetylcysteine inhibits the reaction [[TNFSF10 protein co-treated with gingerol] results in increased cleavage of CASP8 protein]; Acetylcysteine inhibits the reaction [[TNFSF10 protein co-treated with gingerol] results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [[TNFSF10 protein co-treated with tanshinone] results in increased cleavage of PARP1 protein]; Acetylcysteine inhibits the reaction [shogaol promotes the reaction [TNFSF10 protein results in decreased expression of CFLAR protein modified form]]; Acetylcysteine inhibits the reaction [shogaol promotes the reaction [TNFSF10 protein results in increased cleavage of PARP1 protein]]; Acetylcysteine inhibits the reaction [TNFSF10 protein affects the localization of CYCS protein]; Acetylcysteine inhibits the reaction [TNFSF10 protein results in decreased expression of BCL2 protein]; Acetylcysteine inhibits the reaction [TNFSF10 protein results in decreased expression of BCL2L1 protein]; Acetylcysteine inhibits the reaction [TNFSF10 protein results in decreased expression of BID protein]; Acetylcysteine inhibits the reaction [TNFSF10 protein results in decreased expression of BIRC5 protein]; Acetylcysteine inhibits the reaction [TNFSF10 protein results in increased abundance of Reactive Nitrogen Species]; Acetylcysteine inhibits the reaction [TNFSF10 protein results in increased abundance of Reactive Oxygen Species]; Acetylcysteine inhibits the reaction [TNFSF10 protein results in increased activity of CASP3 protein]; Acetylcysteine inhibits the reaction [TNFSF10 protein results in increased activity of CASP8 protein]; Acetylcysteine inhibits the reaction [TNFSF10 protein results in increased activity of CASP9 protein]; Acetylcysteine inhibits the reaction [TNFSF10 protein results in increased chemical synthesis of Reactive Oxygen Species]; Acetylcysteine inhibits the reaction [TNFSF10 protein results in increased expression of BAX protein]; Acetylcysteine inhibits the reaction [TNFSF10 protein results in increased expression of PARP1 protein modified form]; Acetylcysteine inhibits the reaction [TNFSF10 protein results in increased expression of TP53 protein]; Acetylcysteine inhibits the reaction [TNFSF10 protein results in increased expression of VDAC1 protein]

PMID:16084531 PMID:20971099 PMID:23711929 PMID:25034532 PMID:25619640 More...

NCBI chr 2:110,199,835...110,227,239
Ensembl chr 2:110,207,916...110,225,135

G

TNF superfamily member 11

multiple interactions

[Acetylcysteine co-treated with CSF1R protein co-treated with TNFSF11 protein] results in decreased expression of ATP6V0D2 mRNA; [Acetylcysteine co-treated with CSF1R protein co-treated with TNFSF11 protein] results in decreased expression of CTSK mRNA; Acetylcysteine affects the reaction [[NFE2L2 protein affects the susceptibility to sodium arsenite] affects the reaction [[CSF1R protein co-treated with TNFSF11 protein] affects the expression of ATP6V0D2 mRNA]]; Acetylcysteine affects the reaction [[NFE2L2 protein affects the susceptibility to sodium arsenite] affects the reaction [[CSF1R protein co-treated with TNFSF11 protein] affects the expression of CTSK mRNA]]; Acetylcysteine inhibits the reaction [[sodium arsenite co-treated with CSF1R protein co-treated with TNFSF11 protein] results in increased expression of ATP6V0D2 mRNA]; Acetylcysteine inhibits the reaction [[sodium arsenite co-treated with CSF1R protein co-treated with TNFSF11 protein] results in increased expression of CTSK mRNA]

NCBI chr15:53,673,850...53,705,325
Ensembl chr15:53,673,877...53,705,445

G

TNF superfamily member 4

multiple interactions

Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of TNFSF4 mRNA]; Acetylcysteine inhibits the reaction [Vehicle Emissions results in increased expression of TNFSF4 mRNA]

NCBI chr13:73,723,329...73,746,809
Ensembl chr13:73,723,329...73,746,788

G

transportin 1

multiple interactions

Acetylcysteine inhibits the reaction [manumycin results in decreased expression of TNPO1]

NCBI chr 2:30,207,529...30,300,162
Ensembl chr 2:30,211,510...30,300,375

G

translocase of outer mitochondrial membrane 20

multiple interactions

Acetylcysteine inhibits the reaction [chromium hexavalent ion results in decreased expression of TOMM20 protein]

NCBI chr19:54,925,197...54,935,188
Ensembl chr19:54,923,402...54,935,198

G

torsin family 3, member A

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of TOR3A mRNA; Acetylcysteine inhibits the reaction [[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of TOR3A mRNA]

NCBI chr13:68,769,893...68,798,738
Ensembl chr13:68,769,605...68,798,475

G

tumor protein p53

multiple interactions
increases expression
increases phosphorylation
decreases expression
decreases activity

Acetylcysteine inhibits the reaction [2,2'-azobis(2-amidinopropane) results in increased phosphorylation of TRP53 protein]; Acetylcysteine inhibits the reaction [2,4-dibromophenol metabolite results in increased expression of TRP53 protein modified form]; Acetylcysteine inhibits the reaction [2,4-dibromophenol metabolite results in increased expression of TRP53 protein]; Acetylcysteine inhibits the reaction [[Excitatory Amino Acid Agents results in increased abundance of Reactive Oxygen Species] which results in increased activity of TRP53 protein]; Acetylcysteine inhibits the reaction [[Excitatory Amino Acid Agents results in increased abundance of Reactive Oxygen Species] which results in increased expression of TRP53 mRNA]; Acetylcysteine inhibits the reaction [[Excitatory Amino Acid Agents results in increased abundance of Reactive Oxygen Species] which results in increased expression of TRP53 protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in decreased expression of and results in increased phosphorylation of TRP53 protein]; Acetylcysteine inhibits the reaction [dihydrolipoic acid results in increased expression of TRP53 mRNA]; Acetylcysteine inhibits the reaction [Methylmercury Compounds results in increased expression of TRP53 mRNA]; Acetylcysteine inhibits the reaction [quinone analog results in increased expression of TRP53 protein modified form]; Acetylcysteine inhibits the reaction [quinone analog results in increased expression of TRP53 protein]; Acetylcysteine inhibits the reaction [sodium arsenite results in increased expression of TRP53 protein]; Acetylcysteine inhibits the reaction [Zinc results in increased expression of TRP53 protein]
Acetylcysteine results in increased expression of TP53 protein
Acetylcysteine inhibits the reaction [7-ketocholesterol results in increased expression of TP53 protein]; Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of TP53 protein]; Acetylcysteine inhibits the reaction [[sodium arsenite results in increased abundance of Arsenic] which results in increased expression of TP53 mRNA]; Acetylcysteine inhibits the reaction [Aflatoxin B1 promotes the reaction [fumonisin B1 results in increased expression of TP53 protein]]; Acetylcysteine inhibits the reaction [Aflatoxin B1 results in increased expression of TP53 protein]; Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased expression of TP53 protein]; Acetylcysteine inhibits the reaction [Cadmium results in increased phosphorylation of TP53 protein]; Acetylcysteine inhibits the reaction [Fenitrothion results in increased expression of TP53 mRNA]; Acetylcysteine inhibits the reaction [fumonisin B1 promotes the reaction [Aflatoxin B1 results in increased expression of TP53 protein]]; Acetylcysteine inhibits the reaction [Isoproterenol results in increased expression of and results in increased phosphorylation of TP53 protein]; Acetylcysteine inhibits the reaction [Potassium Dichromate results in increased expression of TP53 protein]; Acetylcysteine inhibits the reaction [Quercetin analog results in decreased phosphorylation of TP53 protein]
Acetylcysteine results in increased phosphorylation of TP53 protein
Acetylcysteine results in decreased expression of TP53 protein
Acetylcysteine results in decreased activity of TP53 protein
[Acetylcysteine co-treated with N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine] inhibits the reaction [[Zinc Sulfate co-treated with prolinedithiocarbamate] results in decreased expression of TP53 protein]; Acetylcysteine affects the reaction [4-biphenylamine affects the expression of TP53 protein]; Acetylcysteine inhibits the reaction [2,2'-azobis(2-amidinopropane) results in increased phosphorylation of TP53 protein]; Acetylcysteine inhibits the reaction [2,3,5-trichloro-6-phenyl-(1,4)benzoquinone results in increased expression of TP53 protein modified form]; Acetylcysteine inhibits the reaction [2,3,5-trichloro-6-phenyl-(1,4)benzoquinone results in increased expression of TP53 protein]; Acetylcysteine inhibits the reaction [2-hydroxy-3',5,5'-trimethoxychalcone results in increased expression of TP53 protein]; Acetylcysteine inhibits the reaction [3-(2-hydroxy-4-(1,1-dimethylheptyl)phenyl)-4-(3-hydroxypropyl)cyclohexanol results in increased expression of TP53 protein]; Acetylcysteine inhibits the reaction [[Ascorbic Acid co-treated with Zinc Acetate co-treated with motexafin gadolinium] results in decreased expression of TP53 protein]; Acetylcysteine inhibits the reaction [[CD40LG protein co-treated with IL4 protein] results in increased expression of TP53 protein]; Acetylcysteine inhibits the reaction [[Cisplatin co-treated with Arsenic Trioxide] results in increased phosphorylation of TP53 protein]; Acetylcysteine inhibits the reaction [[Zinc Sulfate co-treated with prolinedithiocarbamate] results in decreased expression of TP53 protein]; Acetylcysteine inhibits the reaction [Aristolochic Acids results in increased phosphorylation of TP53 protein]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of TP53 mRNA]; Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of TP53 protein]; Acetylcysteine inhibits the reaction [arsenite results in increased expression of TP53 protein]; Acetylcysteine inhibits the reaction [ATM protein promotes the reaction [Doxorubicin results in increased activity of TP53 protein]]; Acetylcysteine inhibits the reaction [Camptothecin results in increased expression of TP53 protein modified form]; Acetylcysteine inhibits the reaction [Capsaicin results in increased phosphorylation of TP53 protein]; Acetylcysteine inhibits the reaction [Cisplatin results in increased expression of TP53 protein]; Acetylcysteine inhibits the reaction [Cisplatin results in increased expression of TP53]; Acetylcysteine inhibits the reaction [Cisplatin results in increased glutathionylation of TP53 protein]; Acetylcysteine inhibits the reaction [cobaltous chloride results in increased expression of and results in increased activity of TP53 protein]; Acetylcysteine inhibits the reaction [cyadox results in increased expression of TP53 mRNA]; Acetylcysteine inhibits the reaction [cypermethrin results in increased expression of TP53 mRNA]; Acetylcysteine inhibits the reaction [diallyl disulfide results in increased expression of TP53 protein]; Acetylcysteine inhibits the reaction [dorsomorphin results in increased expression of and results in increased phosphorylation of TP53 protein]; Acetylcysteine inhibits the reaction [Doxorubicin promotes the reaction [ATM protein results in increased phosphorylation of TP53 protein]]; Acetylcysteine inhibits the reaction [Doxorubicin results in increased expression of TP53 protein]; Acetylcysteine inhibits the reaction [Fingolimod Hydrochloride results in increased phosphorylation of TP53 protein]; Acetylcysteine inhibits the reaction [hesperetin results in increased expression of TP53 protein]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased expression of TP53 mRNA]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased expression of TP53 protein]; Acetylcysteine inhibits the reaction [hydroquinone results in increased expression of TP53 protein]; Acetylcysteine inhibits the reaction [Methotrexate results in increased expression of TP53 mRNA]; Acetylcysteine inhibits the reaction [Methotrexate results in increased expression of TP53 protein]; Acetylcysteine inhibits the reaction [N-acetylsphingosine results in increased expression of TP53 mRNA]; Acetylcysteine inhibits the reaction [N-acetylsphingosine results in increased expression of TP53 protein]; Acetylcysteine inhibits the reaction [Oxaliplatin results in increased expression of TP53 protein]; Acetylcysteine inhibits the reaction [Oxygen deficiency results in increased expression of TP53 protein]; Acetylcysteine inhibits the reaction [Particulate Matter results in decreased expression of TP53 protein]; Acetylcysteine inhibits the reaction [perfosfamide results in increased expression of TP53]; Acetylcysteine inhibits the reaction [Phytochemicals results in increased phosphorylation of TP53 protein]; Acetylcysteine inhibits the reaction [Reactive Oxygen Species affects the localization of TP53 protein]; Acetylcysteine inhibits the reaction [thymoquinone results in increased expression of TP53 protein]; Acetylcysteine inhibits the reaction [TNF protein results in increased expression of TP53 mRNA]; Acetylcysteine inhibits the reaction [TNF protein results in increased expression of TP53 protein]; Acetylcysteine inhibits the reaction [TNFSF10 protein results in increased expression of TP53 protein]; Acetylcysteine inhibits the reaction [TP53 protein results in increased abundance of Reactive Oxygen Species]; Acetylcysteine inhibits the reaction [usnic acid results in increased expression of TP53 protein]; Acetylcysteine promotes the reaction [Chlorine results in increased expression of TP53 protein modified form]

PMID:9535218 PMID:10951577 PMID:11864783 PMID:14871840 PMID:15059885 More...

NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524

G

tropomyosin 1

multiple interactions

Acetylcysteine inhibits the reaction [Allylamine results in increased expression of TPM1 mRNA]

NCBI chr 8:67,635,479...67,662,330
Ensembl chr 8:67,635,479...67,662,802

G

thyroid peroxidase

multiple interactions

Acetylcysteine inhibits the reaction [bisphenol A results in decreased expression of TPO mRNA]

NCBI chr 6:46,698,402...46,768,199
Ensembl chr 6:46,698,414...46,768,199

G

Tnf receptor-associated factor 2

multiple interactions

Acetylcysteine inhibits the reaction [tert-Butylhydroperoxide promotes the reaction [ERN1 protein binds to TRAF2 protein]]

NCBI chr 3:8,341,950...8,366,609
Ensembl chr 3:8,341,951...8,366,538

G

TNF receptor associated factor 6

decreases binding
multiple interactions

N-acetyl-cysteine inhibits binding of Traf6 protein to Tab2 in rat neonatal cardiomyocytes
N-acetyl-L-cysteine inhibits the reaction [angiotensin II increases expression of Traf6 protein in rat neonatal cardiomyocytes]

RGD

PMID:27249171 PMID:27249171

RGD:155646134, RGD:155646134

NCBI chr 3:87,963,517...87,988,316
Ensembl chr 3:87,963,514...87,983,507

G

tribbles pseudokinase 1

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of TRIB1 mRNA

NCBI chr 7:91,206,579...91,213,126
Ensembl chr 7:91,206,579...91,214,731

G

tribbles pseudokinase 3

multiple interactions

Acetylcysteine inhibits the reaction [elesclomol results in increased expression of TRIB3 mRNA]
Acetylcysteine inhibits the reaction [4-hydroxy-2-nonenal results in increased expression of TRIB3 mRNA]

PMID:18723479 PMID:24291486

NCBI chr 3:140,809,634...140,815,230
Ensembl chr 3:140,809,043...140,814,497

G

tripartite motif-containing 28

multiple interactions

Acetylcysteine inhibits the reaction [resveratrol results in increased phosphorylation of TRIM28 protein]

NCBI chr 1:73,652,441...73,659,388
Ensembl chr 1:73,652,709...73,659,380

G

trophinin associated protein

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of TROAP mRNA

NCBI chr 7:130,233,534...130,242,369
Ensembl chr 7:130,234,544...130,242,365

G

transient receptor potential cation channel, subfamily A, member 1

multiple interactions

Acetylcysteine inhibits the reaction [[allyl isothiocyanate results in increased activity of TRPA1 protein] which results in increased uptake of Calcium]; Acetylcysteine inhibits the reaction [[Mustard Gas results in increased activity of TRPA1 protein] which results in increased uptake of Calcium]

NCBI chr 5:4,379,862...4,434,133
Ensembl chr 5:4,379,999...4,433,570

G

transient receptor potential cation channel, subfamily C, member 7

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of TRPC7 mRNA

NCBI chr17:7,708,911...7,833,435
Ensembl chr17:7,709,583...7,833,435

G

TSC complex subunit 2

multiple interactions

Acetylcysteine inhibits the reaction [Cadmium Chloride results in increased phosphorylation of TSC2 protein]

NCBI chr10:13,621,135...13,655,773
Ensembl chr10:13,621,136...13,655,951

G

thyroid stimulating hormone subunit beta

multiple interactions

Acetylcysteine inhibits the reaction [TSHB protein results in increased abundance of Hydrogen Peroxide]

NCBI chr 2:190,224,676...190,229,559
Ensembl chr 2:190,224,676...190,229,559

G

thymic stromal lymphopoietin

multiple interactions

Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of TSLP mRNA]; Acetylcysteine inhibits the reaction [Vehicle Emissions results in increased expression of TSLP mRNA]

PMID:18049884 PMID:29753051

NCBI chr18:24,447,409...24,454,244
Ensembl chr18:24,449,844...24,453,548

G

tetraspanin 6

decreases expression

Acetylcysteine results in decreased expression of TSPAN6 mRNA

NCBI chr X:97,092,394...97,099,659
Ensembl chr X:97,092,388...97,099,309

G

tetratricopeptide repeat domain 7B

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of TTC7B mRNA

NCBI chr 6:119,587,389...119,799,167
Ensembl chr 6:119,587,390...119,799,330

G

tetratricopeptide repeat domain 9B

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of TTC9B mRNA

NCBI chr 1:82,953,434...82,955,659
Ensembl chr 1:82,953,434...82,955,616

G

tubulin, beta 3 class III

multiple interactions

Acetylcysteine inhibits the reaction [Particulate Matter results in decreased expression of TUBB3 mRNA]

NCBI chr19:51,457,187...51,466,243
Ensembl chr19:51,457,184...51,466,243

G

thioredoxin 1

multiple interactions
decreases expression

Acetylcysteine inhibits the reaction [arsenic trioxide results in decreased expression of TXN protein]; Acetylcysteine inhibits the reaction [Rotenone inhibits the reaction [TXN protein binds to and results in decreased activity of MAP3K5 protein]]
Acetylcysteine results in decreased expression of TXN protein
Acetylcysteine inhibits the reaction [Acrolein results in increased oxidation of TXN protein]; Acetylcysteine inhibits the reaction [Mercuric Chloride results in decreased expression of TXN protein]; Acetylcysteine inhibits the reaction [NCX 4040 results in increased oxidation of TXN1 protein]

PMID:16449798 PMID:17959236 PMID:18023956 PMID:18922898 PMID:24157283

NCBI chr 5:72,712,334...72,724,564
Ensembl chr 5:72,711,933...72,724,629

G

thioredoxin 2

multiple interactions

Acetylcysteine inhibits the reaction [bisphenol A results in increased expression of TXN2 mRNA]

NCBI chr 7:109,496,772...109,510,378
Ensembl chr 7:109,496,761...109,510,359

G

thioredoxin domain containing 8

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of TXNDC8 mRNA

NCBI chr 5:72,749,708...72,785,858
Ensembl chr 5:72,749,725...72,785,931

G

thioredoxin interacting protein

multiple interactions

Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of TXNIP mRNA]; Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of TXNIP protein]

NCBI chr 2:184,093,079...184,096,882
Ensembl chr 2:184,092,991...184,096,886

G

thioredoxin-like 1

decreases expression

Acetylcysteine results in decreased expression of TXNL1 mRNA

NCBI chr18:57,125,362...57,155,167
Ensembl chr18:57,125,369...57,165,266

G

thioredoxin reductase 1

multiple interactions

Acetylcysteine inhibits the reaction [Acrolein results in increased expression of TXNRD1 mRNA]

NCBI chr 7:20,830,042...20,914,990
Ensembl chr 7:20,830,045...20,907,863

G

thymidine phosphorylase

multiple interactions

Acetylcysteine inhibits the reaction [[TYMP protein co-treated with Thymidine] results in increased expression of HMOX1 protein]

NCBI chr 7:120,438,768...120,444,088
Ensembl chr 7:120,438,770...120,443,874
Ensembl chr 7:120,438,770...120,443,874

G

tyrosinase

multiple interactions

[Acetylcysteine co-treated with 6-formylindolo(3,2-b)carbazole] results in increased activity of TYR protein; [Acetylcysteine co-treated with Benzo(a)pyrene] results in increased activity of TYR protein

NCBI chr 1:141,115,036...141,210,207
Ensembl chr 1:141,115,036...141,210,207

G

ubiquitin-like modifier activating enzyme 7

increases expression
multiple interactions

Acetylcysteine results in increased expression of UBA7 protein
Acetylcysteine inhibits the reaction [Paraquat results in increased methylation of UBA7 mRNA]
Curcumin affects the reaction [Acetylcysteine results in increased expression of UBA7 protein]; epigallocatechin gallate affects the reaction [Acetylcysteine results in increased expression of UBA7 protein]; Resveratrol affects the reaction [Acetylcysteine results in increased expression of UBA7 protein]

PMID:25649257 PMID:34425375

NCBI chr 8:108,665,289...108,674,097
Ensembl chr 8:108,665,292...108,674,099

G

uncoupling protein 2

multiple interactions

Acetylcysteine inhibits the reaction [Cadmium Chloride results in decreased expression of UCP2 mRNA]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased expression of UCP2 protein]; Acetylcysteine inhibits the reaction [pirinixic acid results in increased expression of UCP2 protein]
Acetylcysteine inhibits the reaction [Doxorubicin results in decreased expression of UCP2 mRNA]; Acetylcysteine inhibits the reaction [Doxorubicin results in decreased expression of UCP2 protein]

PMID:18183618 PMID:29061315 PMID:30104959 PMID:36493885

NCBI chr 1:154,839,242...154,845,612
Ensembl chr 1:154,839,209...154,845,611

G

ubiquitin-fold modifier 1

multiple interactions

Acetylcysteine inhibits the reaction [elesclomol results in increased expression of UFM1 mRNA]

NCBI chr 2:137,969,476...137,977,620
Ensembl chr 2:137,966,678...137,978,089
Ensembl chr 2:137,966,678...137,978,089

G

UDP-glucose 6-dehydrogenase

increases expression

Acetylcysteine results in increased expression of UGDH mRNA

NCBI chr14:42,848,704...42,872,351
Ensembl chr14:42,848,854...42,872,354

G

UDP glucuronosyltransferase family 1 member A6

multiple interactions

Acetylcysteine inhibits the reaction [[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of UGT1A6 mRNA]; Acetylcysteine inhibits the reaction [Vitamin K 3 results in increased activity of UGT1A6 promoter]

PMID:15336321 PMID:22129741

NCBI chr 9:88,747,213...88,808,465
Ensembl chr 9:88,713,184...88,808,465

G

ubiquitin-like with PHD and ring finger domains 1

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of UHRF1 mRNA

NCBI chr 9:1,133,117...1,154,639
Ensembl chr 9:1,134,909...1,154,631

G

unc-51 like autophagy activating kinase 1

multiple interactions

Acetylcysteine inhibits the reaction [Artesunate results in increased phosphorylation of ULK1 protein]; Acetylcysteine inhibits the reaction [cucurbitacin E results in decreased expression of and results in decreased phosphorylation of ULK1 protein]

PMID:27106530 PMID:33002460

NCBI chr12:45,851,710...45,877,966
Ensembl chr12:45,851,710...45,877,966

G

ubiquitin specific peptidase like 1

multiple interactions

Acetylcysteine inhibits the reaction [elesclomol results in increased expression of USPL1 mRNA]

NCBI chr12:5,823,460...5,850,470
Ensembl chr12:5,823,359...5,850,366

G

UV radiation resistance associated

multiple interactions

Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of UVRAG mRNA]

NCBI chr 1:153,185,356...153,442,200
Ensembl chr 1:153,185,395...153,442,136

G

vascular cell adhesion molecule 1

multiple interactions

Acetylcysteine inhibits the reaction [Drugs, Chinese Herbal inhibits the reaction [lipopolysaccharide, E coli O55-B5 results in increased expression of VCAM1 protein]]
Acetylcysteine inhibits the reaction [2,3,5-trichloro-6-phenyl-(1,4)benzoquinone results in increased expression of VCAM1 protein]; Acetylcysteine inhibits the reaction [IL1B protein results in increased expression of VCAM1 mRNA]; Acetylcysteine inhibits the reaction [IL1B protein results in increased expression of VCAM1 protein]; Acetylcysteine inhibits the reaction [Lipopolysaccharides results in increased expression of VCAM1 protein]; Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of VCAM1 protein]; Acetylcysteine inhibits the reaction [tetrachlorobenzoquinone results in increased expression of VCAM1 protein]; Acetylcysteine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of VCAM1 protein]; Acetylcysteine inhibits the reaction [TNF protein results in increased expression of VCAM1 protein]

PMID:12615669 PMID:19281832 PMID:19642688 PMID:25876056 PMID:26901245 More...

NCBI chr 2:204,038,120...204,057,852
Ensembl chr 2:204,038,114...204,057,958

G

voltage-dependent anion channel 1

multiple interactions

Acetylcysteine inhibits the reaction [chromium hexavalent ion results in increased expression of VDAC1 mRNA]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide promotes the reaction [VDAC1 protein binds to VDAC1 protein]]; Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased expression of VDAC1 protein]; Acetylcysteine inhibits the reaction [quinocetone promotes the reaction [VDAC1 protein binds to VDAC1 protein]]; Acetylcysteine inhibits the reaction [quinocetone results in increased expression of VDAC1 protein]; Acetylcysteine inhibits the reaction [TNFSF10 protein results in increased expression of VDAC1 protein]

PMID:22858589 PMID:23711929 PMID:28343033

NCBI chr10:36,532,306...36,559,642
Ensembl chr10:36,532,244...36,559,640

G

voltage-dependent anion channel 2

multiple interactions

Acetylcysteine inhibits the reaction [quinocetone promotes the reaction [VDAC2 protein binds to VDAC2 protein]]

NCBI chr15:2,462,877...2,476,802
Ensembl chr15:2,463,056...2,476,553

G

vascular endothelial growth factor A

decreases secretion
multiple interactions
decreases expression

Acetylcysteine results in decreased secretion of VEGFA protein
Acetylcysteine inhibits the reaction [cobaltous chloride results in increased expression of VEGFA mRNA]
Acetylcysteine inhibits the reaction [cobaltous chloride results in increased secretion of VEGFA protein]
Acetylcysteine results in decreased expression of VEGFA mRNA
Acetylcysteine inhibits the reaction [27-hydroxycholesterol results in increased expression of VEGFA mRNA]; Acetylcysteine inhibits the reaction [27-hydroxycholesterol results in increased secretion of VEGFA protein]; Acetylcysteine inhibits the reaction [[Peanut Oil results in increased abundance of Particulate Matter] which results in decreased expression of VEGFA protein]; Acetylcysteine inhibits the reaction [[Peanut Oil results in increased abundance of Particulate Matter] which results in increased expression of VEGFA mRNA]; Acetylcysteine inhibits the reaction [[Tetradecanoylphorbol Acetate co-treated with Hydrogen Peroxide] results in increased secretion of VEGFA protein]; Acetylcysteine inhibits the reaction [[Tretinoin co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of VEGFA protein]; Acetylcysteine inhibits the reaction [Antimycin A results in increased expression of VEGFA mRNA]; Acetylcysteine inhibits the reaction [cobaltous chloride results in increased expression of VEGFA mRNA]; Acetylcysteine inhibits the reaction [cobaltous chloride results in increased expression of VEGFA protein]; Acetylcysteine inhibits the reaction [EGF protein results in increased secretion of VEGFA mRNA]; Acetylcysteine inhibits the reaction [EGF protein results in increased secretion of VEGFA protein]; Acetylcysteine inhibits the reaction [hydroxyethyl methacrylate results in decreased secretion of VEGFA protein]; Acetylcysteine inhibits the reaction [SOD2 protein affects the expression of VEGFA mRNA]; Acetylcysteine inhibits the reaction [sodium arsenite results in increased expression of VEGFA mRNA]; Acetylcysteine inhibits the reaction [sodium arsenite results in increased secretion of VEGFA protein]; Acetylcysteine inhibits the reaction [Tetradecanoylphorbol Acetate results in increased secretion of VEGFA protein]; Acetylcysteine inhibits the reaction [TGFB1 protein results in increased expression of VEGFA protein]

PMID:11214823 PMID:11641398 PMID:11886167 PMID:13679210 PMID:15788408 More...

NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641

G

vascular endothelial growth factor B

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of VEGFB mRNA

NCBI chr 1:204,172,297...204,178,046
Ensembl chr 1:204,172,225...204,177,944

G

vimentin

multiple interactions
decreases expression

Acetylcysteine inhibits the reaction [27-hydroxycholesterol results in increased expression of VIM protein]; Acetylcysteine inhibits the reaction [3,4,5,3',4'-pentachlorobiphenyl results in increased expression of VIM mRNA]; Acetylcysteine inhibits the reaction [[Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of VIM protein]; Acetylcysteine inhibits the reaction [di-n-propyldithiocarbamate results in decreased expression of VIM protein]
Acetylcysteine results in decreased expression of VIM protein
Acetylcysteine inhibits the reaction [Hydrogen Peroxide results in increased expression of VIM protein]; Acetylcysteine inhibits the reaction [SHC1 protein results in increased expression of VIM protein]

PMID:28284859 PMID:32659284 PMID:32687844 PMID:33131013 PMID:34687772

NCBI chr17:76,668,701...76,677,186
Ensembl chr17:76,668,647...76,677,187

G

vitelline membrane outer layer 1 homolog

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of VMO1 mRNA; Acetylcysteine inhibits the reaction [[indole-3-carbinol co-treated with Diethylnitrosamine] results in increased expression of VMO1 mRNA]

NCBI chr10:55,227,944...55,234,794
Ensembl chr10:55,227,944...55,229,289

G

vanin 1

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in increased expression of VNN1 mRNA

NCBI chr 1:21,537,084...21,547,395
Ensembl chr 1:21,537,094...21,547,395

G

Wnt family member 1

multiple interactions

Acetylcysteine inhibits the reaction [quinocetone results in decreased expression of WNT1 protein]

NCBI chr 7:129,938,604...129,942,651
Ensembl chr 7:129,938,604...129,942,651

G

WT1 associated protein

multiple interactions

Acetylcysteine inhibits the reaction [sodium arsenite results in increased expression of WTAP mRNA]; Acetylcysteine inhibits the reaction [sodium arsenite results in increased expression of WTAP protein]

NCBI chr 1:47,665,965...47,691,067
Ensembl chr 1:47,665,965...47,691,065

G

X-box binding protein 1

increases splicing
multiple interactions

Acetylcysteine results in increased splicing of XBP1 mRNA
Acetylcysteine inhibits the reaction [Ethylmercury Compounds results in increased splicing of XBP1 mRNA]; Acetylcysteine inhibits the reaction [XBP1 protein inhibits the reaction [arsenic trioxide results in increased abundance of Reactive Oxygen Species]]; Acetylcysteine inhibits the reaction [XBP1 protein inhibits the reaction [Hydrogen Peroxide results in increased abundance of Reactive Oxygen Species]]
Acetylcysteine inhibits the reaction [chloroacetic acid results in increased expression of XBP1 protein alternative form]; Acetylcysteine inhibits the reaction [methylmercuric chloride results in increased expression of XBP1 protein alternative form]; Acetylcysteine inhibits the reaction [mono-(2-ethylhexyl)phthalate results in increased expression of XBP1 protein alternative form]; Acetylcysteine inhibits the reaction [sodium arsenite results in increased expression of XBP1 protein alternative form]
Acetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of XBP1 protein]; Acetylcysteine inhibits the reaction [Sodium Fluoride results in increased splicing of XBP1 mRNA]

PMID:19722195 PMID:21138464 PMID:21145380 PMID:21911445 PMID:25451595 More...

NCBI chr14:80,390,629...80,395,713
Ensembl chr14:80,390,643...80,395,693

G

xanthine dehydrogenase

multiple interactions

[MPO protein co-treated with XDH protein co-treated with Acetaldehyde] promotes the reaction [Serotonin binds to Acetylcysteine]

NCBI chr 6:21,530,463...21,592,172
Ensembl chr 6:21,530,113...21,592,268

G

X-linked inhibitor of apoptosis

multiple interactions

Acetylcysteine inhibits the reaction [[Bortezomib co-treated with Butyrates] results in decreased expression of XIAP protein]; Acetylcysteine inhibits the reaction [[Bortezomib co-treated with vorinostat] results in decreased expression of XIAP protein]; Acetylcysteine inhibits the reaction [cordycepin results in decreased expression of XIAP protein]; Acetylcysteine inhibits the reaction [diallyl trisulfide results in decreased expression of XIAP protein]; Acetylcysteine inhibits the reaction [Tosylphenylalanyl Chloromethyl Ketone results in increased cleavage of XIAP protein]

PMID:15173093 PMID:19679660 PMID:21310227 PMID:22578287

NCBI chr X:120,890,537...120,938,413
Ensembl chr X:120,897,907...120,934,700

G

X-ray repair cross complementing 1

multiple interactions

Acetylcysteine inhibits the reaction [2,2',4,4'-tetrabromodiphenyl ether results in decreased expression of XRCC1 mRNA]
Acetylcysteine inhibits the reaction [XRCC1 gene mutant form results in decreased abundance of Adenosine Triphosphate]; Acetylcysteine inhibits the reaction [XRCC1 gene mutant form results in increased abundance of Malondialdehyde]; Acetylcysteine promotes the reaction [XRCC1 protein results in decreased abundance of Malondialdehyde]; Acetylcysteine promotes the reaction [XRCC1 protein results in decreased oxidation of Glutathione]; Acetylcysteine promotes the reaction [XRCC1 protein results in increased abundance of Adenosine Triphosphate]; Acetylcysteine promotes the reaction [XRCC1 protein results in increased activity of CAT protein]; Acetylcysteine promotes the reaction [XRCC1 protein results in increased expression of CYTB mRNA]; Acetylcysteine promotes the reaction [XRCC1 protein results in increased expression of ND2 mRNA]; Acetylcysteine promotes the reaction [XRCC1 protein results in increased expression of ND5 mRNA]

PMID:18948301 PMID:30998386

NCBI chr 1:80,140,495...80,168,705
Ensembl chr 1:80,141,207...80,168,701

G

X-ray repair cross complementing 3

multiple interactions

Acetylcysteine inhibits the reaction [2,2',4,4'-tetrabromodiphenyl ether results in increased expression of XRCC3 mRNA]

NCBI chr 6:130,863,405...130,873,765
Ensembl chr 6:130,863,959...130,872,444

G

X-ray repair cross complementing 6

multiple interactions

Acetylcysteine promotes the reaction [Acrylonitrile results in increased expression of XRCC6 mRNA]

NCBI chr 7:113,542,992...113,563,762
Ensembl chr 7:113,543,057...113,563,762

G

tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, eta

multiple interactions

Acetylcysteine inhibits the reaction [27-hydroxycholesterol inhibits the reaction [YWHAH protein binds to CTNNB1 protein]]; Acetylcysteine inhibits the reaction [27-hydroxycholesterol inhibits the reaction [YWHAH protein binds to GSK3B protein]]

NCBI chr14:77,696,332...77,705,715
Ensembl chr14:77,696,333...77,705,741

G

YY1 transcription factor

multiple interactions

Acetylcysteine inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased expression of YY1 mRNA]; Acetylcysteine inhibits the reaction [[manganese chloride results in increased abundance of Manganese] which results in increased expression of YY1 protein]

NCBI chr 6:127,706,739...127,736,499
Ensembl chr 6:127,707,596...127,732,747

G

zinc finger and BTB domain containing 16

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of ZBTB16 mRNA

NCBI chr 8:48,989,376...49,177,011
Ensembl chr 8:48,994,566...49,177,011

G

zinc finger DHHC-type palmitoyltransferase 19

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of ZDHHC19 mRNA

NCBI chr11:68,277,847...68,289,110
Ensembl chr11:68,277,848...68,288,954

G

zinc finger AN1-type containing 2A

multiple interactions

Acetylcysteine inhibits the reaction [elesclomol results in increased expression of ZFAND2A mRNA]

NCBI chr12:15,161,601...15,172,679
Ensembl chr12:15,161,639...15,172,677

G

zinc finger homeobox 4

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of ZFHX4 mRNA

NCBI chr 2:96,224,763...96,408,245
Ensembl chr 2:96,224,767...96,408,228

G

zinc finger protein 36, C3H type-like 2

increases expression

Acetylcysteine results in increased expression of ZFP36L2 mRNA

NCBI chr 6:10,490,032...10,494,073
Ensembl chr 6:10,490,032...10,494,064

G

zinc finger protein 394

multiple interactions

Acetylcysteine inhibits the reaction [elesclomol results in increased expression of ZNF394 mRNA]

NCBI chr12:9,409,047...9,417,228
Ensembl chr12:9,409,078...9,417,246

G

zinc finger protein 395

multiple interactions

[indole-3-carbinol co-treated with Diethylnitrosamine co-treated with Acetylcysteine] results in decreased expression of ZFP395 mRNA

NCBI chr15:39,581,603...39,621,911
Ensembl chr15:39,608,080...39,619,950

G

zinc finger MYM-type containing 2

decreases expression

Acetylcysteine results in decreased expression of ZMYM2 mRNA

NCBI chr15:31,035,835...31,108,945
Ensembl chr15:31,035,838...31,109,357

N-acetyl-L-methionine

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

glutamate dehydrogenase 1

decreases activity

N-acetylmethionine results in decreased activity of GLUD1 protein

NCBI chr16:9,640,312...9,673,961
Ensembl chr16:9,640,312...9,673,957

N-acetyl-L-tryptophan

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

acetylcholinesterase

multiple interactions

N-acetyltryptophan inhibits the reaction [Aluminum Chloride results in decreased activity of ACHE protein]

NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651

N-acetyl-S-phenyl-L-cysteine

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

cytochrome P450, family 2, subfamily d, polypeptide 4

affects abundance

CYP2D6 affects the abundance of S-phenyl-N-acetylcysteine

NCBI chr 7:113,882,584...113,891,754
Ensembl chr 7:113,881,618...113,891,759

G

cytochrome P450, family 2, subfamily e, polypeptide 1

multiple interactions

[CYP2E1 protein affects the metabolism of Benzene] which affects the chemical synthesis of S-phenyl-N-acetylcysteine

NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023

G

glutathione S-transferase alpha 1

affects abundance
multiple interactions

GSTA1 gene polymorphism affects the abundance of S-phenyl-N-acetylcysteine
GSTA1 gene polymorphism affects the reaction [GSTM1 gene polymorphism affects the abundance of S-phenyl-N-acetylcysteine]

NCBI chr 9:23,703,476...23,720,121
Ensembl chr 9:23,703,477...23,720,121

G

glutathione S-transferase mu 1

affects abundance
multiple interactions

GSTM1 gene polymorphism affects the abundance of S-phenyl-N-acetylcysteine; GSTM1 polymorphism affects the abundance of S-phenyl-N-acetylcysteine
[GSTM1 polymorphism co-treated with Smoke] affects the abundance of S-phenyl-N-acetylcysteine; GSTA1 gene polymorphism affects the reaction [GSTM1 gene polymorphism affects the abundance of S-phenyl-N-acetylcysteine]; GSTT1 gene polymorphism affects the reaction [GSTM1 gene polymorphism affects the abundance of S-phenyl-N-acetylcysteine]

PMID:17056211 PMID:20100551 PMID:21300142

NCBI chr 2:195,649,845...195,655,402
Ensembl chr 2:195,649,845...195,655,411

G

glutathione S-transferase theta 1

multiple interactions
affects abundance
affects chemical synthesis

[GSTT1 gene SNP affects the metabolism of Benzene] which affects the abundance of S-phenyl-N-acetylcysteine; GSTT1 gene polymorphism affects the reaction [GSTM1 gene polymorphism affects the abundance of S-phenyl-N-acetylcysteine]
GSTT1 gene polymorphism affects the abundance of S-phenyl-N-acetylcysteine; GSTT1 polymorphism affects the abundance of S-phenyl-N-acetylcysteine
GSTT1 protein polymorphism affects the chemical synthesis of S-phenyl-N-acetylcysteine

PMID:15533900 PMID:15935803 PMID:20100551 PMID:21300142 PMID:30086327

NCBI chr20:12,856,613...12,873,586
Ensembl chr20:12,856,669...12,873,585

G

NAD(P)H quinone dehydrogenase 1

affects abundance

NQO1 affects the abundance of S-phenyl-N-acetylcysteine; NQO1 polymorphism affects the abundance of S-phenyl-N-acetylcysteine

PMID:10780264 PMID:12798093

NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557

S-nitroso-N-acetyl-D-penicillamine

term browser

Symbol

Object Name

Qualifiers

Evidence

Notes

Source

PubMed Reference(s)

RGD Reference(s)

Position

G

apoptosis inducing factor, mitochondria associated 1

multiple interactions

AIFM1 protein inhibits the reaction [S-Nitroso-N-Acetylpenicillamine results in decreased reduction of Glutathione]; AIFM1 protein promotes the reaction [S-Nitroso-N-Acetylpenicillamine results in decreased reduction of Adenine Nucleotides]

NCBI chr X:127,650,223...127,689,356
Ensembl chr X:127,650,226...127,689,256

G

AKT serine/threonine kinase 1

multiple interactions
decreases phosphorylation

2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one promotes the reaction [Melatonin inhibits the reaction [S-Nitroso-N-Acetylpenicillamine results in decreased phosphorylation of AKT1 protein]]; Melatonin inhibits the reaction [S-Nitroso-N-Acetylpenicillamine results in decreased phosphorylation of AKT1 protein]; wortmannin promotes the reaction [Melatonin inhibits the reaction [S-Nitroso-N-Acetylpenicillamine results in decreased phosphorylation of AKT1 protein]]

NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921

G

aquaporin 3 (Gill blood group)

decreases expression

S-Nitroso-N-Acetylpenicillamine results in decreased expression of AQP3 mRNA

NCBI chr 5:56,239,200...56,244,718
Ensembl chr 5:56,239,201...56,244,720

G

BCL2-associated agonist of cell death

decreases phosphorylation
multiple interactions

S-Nitroso-N-Acetylpenicillamine results in decreased phosphorylation of BAD protein
Melatonin inhibits the reaction [S-Nitroso-N-Acetylpenicillamine results in decreased phosphorylation of BAD protein]

NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823

G

BCL2 associated X, apoptosis regulator

increases expression
multiple interactions

S-Nitroso-N-Acetylpenicillamine results in increased expression of BAX protein
Melatonin inhibits the reaction [S-Nitroso-N-Acetylpenicillamine results in increased expression of BAX protein]

NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368

G

BCL2, apoptosis regulator

multiple interactions
decreases expression

Melatonin inhibits the reaction [S-Nitroso-N-Acetylpenicillamine results in decreased expression of BCL2 protein]
S-Nitroso-N-Acetylpenicillamine results in decreased expression of BCL2 mRNA; S-Nitroso-N-Acetylpenicillamine results in decreased expression of BCL2 protein

PMID:17135264 PMID:21138475

NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743
Ensembl chr13:22,684,989...22,853,743

G

calcitonin-related polypeptide alpha

multiple interactions
increases secretion

Carbon Dioxide inhibits the reaction [S-Nitroso-N-Acetylpenicillamine results in increased secretion of CALCA protein]

NCBI chr 1:168,878,212...168,883,176
Ensembl chr 1:168,878,214...168,883,105

G

caspase 1

multiple interactions

[S-Nitroso-N-Acetylpenicillamine results in increased abundance of Nitric Oxide] which results in increased activity of and results in increased cleavage of CASP1 protein

NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383

G

caspase 3

multiple interactions
decreases activity
increases activity

[S-Nitroso-N-Acetylpenicillamine results in increased abundance of Nitric Oxide] inhibits the reaction [N-caproylsphingosine promotes the reaction [CASP3 protein results in increased cleavage of PARP1 protein]]; [S-Nitroso-N-Acetylpenicillamine results in increased abundance of Nitric Oxide] inhibits the reaction [N-caproylsphingosine results in increased activity of CASP3 protein]
Melatonin inhibits the reaction [S-Nitroso-N-Acetylpenicillamine results in increased activity of CASP3 protein]
S-Nitroso-N-Acetylpenicillamine results in decreased activity of CASP3 protein

PMID:10811113 PMID:12006578 PMID:12220328

NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648

G

cAMP responsive element binding protein 1

multiple interactions

S-Nitroso-N-Acetylpenicillamine inhibits the reaction [3,5-dimethoxy-4'-hydroxystilbene results in decreased phosphorylation of CREB1 protein]; S-Nitroso-N-Acetylpenicillamine inhibits the reaction [Quercetin results in decreased phosphorylation of CREB1 protein]

NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816

G

cysteine and glycine rich protein 3

decreases expression

S-Nitroso-N-Acetylpenicillamine results in decreased expression of CSRP3 mRNA

NCBI chr 1:98,528,067...98,546,647
Ensembl chr 1:98,528,068...98,546,653

G

dorsal root ganglia homeobox

decreases expression

S-Nitroso-N-Acetylpenicillamine results in decreased expression of DRGX mRNA

NCBI chr16:7,854,849...7,884,404
Ensembl chr16:7,854,849...7,900,600

G

endothelin 1

increases secretion

S-Nitroso-N-Acetylpenicillamine results in increased secretion of EDN1 protein

NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885

G

elastin

decreases expression

S-Nitroso-N-Acetylpenicillamine results in decreased expression of ELN mRNA

NCBI chr12:21,968,544...22,011,929
Ensembl chr12:21,968,544...22,011,928

G

exocyst complex component 6

decreases expression

S-Nitroso-N-Acetylpenicillamine results in decreased expression of SEC15 mRNA

NCBI chr 1:235,314,612...235,457,824
Ensembl chr 1:235,300,369...235,457,015

G

Fas ligand

multiple interactions

[S-Nitroso-N-Acetylpenicillamine results in increased abundance of Nitric Oxide] inhibits the reaction [Etoposide results in increased activity of FASLG promoter]; [S-Nitroso-N-Acetylpenicillamine results in increased abundance of Nitric Oxide] inhibits the reaction [N-caproylsphingosine results in increased activity of FASLG promoter]

NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215

G

Fc gamma receptor 2A

decreases expression

S-Nitroso-N-Acetylpenicillamine results in decreased expression of FCGR3 mRNA

NCBI chr13:83,280,782...83,297,535
Ensembl chr13:83,280,784...83,295,967

G

Fc gamma receptor 2B

decreases expression

S-Nitroso-N-Acetylpenicillamine results in decreased expression of FCGR2B mRNA

NCBI chr13:83,191,253...83,207,778
Ensembl chr13:83,193,163...83,207,778

G

fibroblast growth factor 2

multiple interactions

S-Nitroso-N-Acetylpenicillamine promotes the reaction [FGF2 protein results in increased expression of TP53 protein]

NCBI chr 2:120,236,328...120,290,673
Ensembl chr 2:120,236,328...120,291,221

G

growth hormone releasing hormone

decreases expression

S-Nitroso-N-Acetylpenicillamine results in decreased expression of GHRH mRNA

NCBI chr 3:145,992,762...146,012,528
Ensembl chr 3:145,992,763...146,011,889

G

G protein subunit alpha i2

multiple interactions
decreases expression

8-Bromo Cyclic Adenosine Monophosphate inhibits the reaction [S-Nitroso-N-Acetylpenicillamine results in decreased expression of GNAI2 protein]; manganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [S-Nitroso-N-Acetylpenicillamine results in decreased expression of GNAI2 protein]; Uric Acid inhibits the reaction [S-Nitroso-N-Acetylpenicillamine results in decreased expression of GNAI2 protein]

PMID:16962941 PMID:19252090

NCBI chr 8:108,288,401...108,309,009
Ensembl chr 8:108,288,401...108,308,979

G

G protein subunit alpha i3

multiple interactions
decreases expression

8-Bromo Cyclic Adenosine Monophosphate inhibits the reaction [S-Nitroso-N-Acetylpenicillamine results in decreased expression of GNAI3 protein]; manganese(III)-tetrakis(4-benzoic acid)porphyrin inhibits the reaction [S-Nitroso-N-Acetylpenicillamine results in decreased expression of GNAI3 protein]; Uric Acid inhibits the reaction [S-Nitroso-N-Acetylpenicillamine results in decreased expression of GNAI3 protein]

PMID:16962941 PMID:19252090

NCBI chr 2:195,742,765...195,780,720
Ensembl chr 2:195,742,642...195,780,742

G

glutamic-oxaloacetic transaminase 1

decreases expression

S-Nitroso-N-Acetylpenicillamine results in decreased expression of GOT1 mRNA

NCBI chr 1:242,357,293...242,381,535
Ensembl chr 1:242,357,306...242,380,633

G

glutathione peroxidase 1

multiple interactions

GPX1 protein affects the reaction [S-Nitroso-N-Acetylpenicillamine promotes the reaction [Diquat results in decreased activity of SOD1 protein]]; GPX1 protein affects the reaction [S-Nitroso-N-Acetylpenicillamine promotes the reaction [Diquat results in increased activity of SOD2 protein]]; GPX1 protein affects the susceptibility to [Diquat co-treated with S-Nitroso-N-Acetylpenicillamine]; S-Nitroso-N-Acetylpenicillamine promotes the reaction [Diquat results in decreased expression of GPX1 protein]

NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024

G

glutathione S-transferase alpha 2

multiple interactions

[S-Nitroso-N-Acetylpenicillamine co-treated with 2-tert-butylhydroquinone] results in increased expression of GSTA2

NCBI chr 8:79,184,535...79,196,827
Ensembl chr 8:79,184,322...79,196,798

G

HCK proto-oncogene, Src family tyrosine kinase

decreases expression

S-Nitroso-N-Acetylpenicillamine results in decreased expression of HCK mRNA

NCBI chr 3:141,571,587...141,614,696
Ensembl chr 3:141,571,587...141,614,693

G

heme oxygenase 1

increases expression

S-Nitroso-N-Acetylpenicillamine results in increased expression of HMOX1 protein

NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079

G

interferon gamma

multiple interactions

S-Nitroso-N-Acetylpenicillamine inhibits the reaction [Streptozocin results in increased expression of IFNG protein]

NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375

G

inositol-trisphosphate 3-kinase A

decreases expression

S-Nitroso-N-Acetylpenicillamine results in decreased expression of ITPKA mRNA

NCBI chr 3:106,726,036...106,734,601
Ensembl chr 3:106,726,036...106,734,600

G

mitogen activated protein kinase 1

decreases expression
decreases phosphorylation
increases phosphorylation
multiple interactions

S-Nitroso-N-Acetylpenicillamine results in decreased expression of MAPK1 protein
S-Nitroso-N-Acetylpenicillamine results in decreased phosphorylation of MAPK1 protein
S-Nitroso-N-Acetylpenicillamine results in increased phosphorylation of MAPK1 protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [S-Nitroso-N-Acetylpenicillamine results in increased phosphorylation of MAPK1 protein]; 8-Bromo Cyclic Adenosine Monophosphate inhibits the reaction [S-Nitroso-N-Acetylpenicillamine results in decreased phosphorylation of MAPK1 protein]

PMID:15640287 PMID:19252090

NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616

G

mitogen activated protein kinase 3

decreases expression
multiple interactions
increases phosphorylation
decreases phosphorylation

S-Nitroso-N-Acetylpenicillamine results in decreased expression of MAPK3 protein
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [S-Nitroso-N-Acetylpenicillamine results in increased phosphorylation of MAPK3 protein]; 8-Bromo Cyclic Adenosine Monophosphate inhibits the reaction [S-Nitroso-N-Acetylpenicillamine results in decreased phosphorylation of MAPK3 protein]

PMID:15640287 PMID:19252090

NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863

G

membrane metallo-endopeptidase

decreases expression

S-Nitroso-N-Acetylpenicillamine results in decreased expression of MME mRNA

NCBI chr 2:147,686,913...147,803,808
Ensembl chr 2:147,722,086...147,803,792

G

metal-regulatory transcription factor 1

affects localization

S-Nitroso-N-Acetylpenicillamine affects the localization of MTF1 protein

NCBI chr 5:137,062,319...137,107,136
Ensembl chr 5:137,062,376...137,107,136

G

nuclear factor kappa B subunit 1

decreases expression

S-Nitroso-N-Acetylpenicillamine results in decreased expression of NFKB1 mRNA

NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404

G

nitric oxide synthase 2

decreases activity
decreases expression

S-Nitroso-N-Acetylpenicillamine results in decreased activity of NOS2 protein
S-Nitroso-N-Acetylpenicillamine results in decreased expression of NOS2 promoter

PMID:11076874 PMID:15565661

NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210

G

natriuretic peptide A

multiple interactions

[S-Nitroso-N-Acetylpenicillamine co-treated with PRKG1 protein alternative form] inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]

NCBI chr 5:158,429,042...158,430,351
Ensembl chr 5:158,429,042...158,430,351

G

natriuretic peptide receptor 3

multiple interactions
decreases expression

2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [S-Nitroso-N-Acetylpenicillamine results in decreased expression of NPR3 protein]

PMID:16962941 PMID:19252090

NCBI chr 2:60,865,483...60,933,432
Ensembl chr 2:60,870,594...60,932,955

G

opioid receptor, mu 1

multiple interactions

N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [S-Nitroso-N-Acetylpenicillamine promotes the reaction [OPRM1 protein binds to PRKCG protein]]; S-Nitroso-N-Acetylpenicillamine promotes the reaction [OPRM1 protein binds to PRKCA protein]; S-Nitroso-N-Acetylpenicillamine promotes the reaction [OPRM1 protein binds to PRKCG protein]; S-Nitroso-N-Acetylpenicillamine promotes the reaction [OPRM1 protein binds to RAF1 protein]; S-Nitroso-N-Acetylpenicillamine promotes the reaction [OPRM1 protein binds to RGS17 protein]

PMID:18652891 PMID:21235400

NCBI chr 1:43,160,057...43,413,409
Ensembl chr 1:43,160,057...43,413,409

G

peptidylglycine alpha-amidating monooxygenase

decreases expression

S-Nitroso-N-Acetylpenicillamine results in decreased expression of PAM mRNA

NCBI chr 9:97,998,581...98,271,966
Ensembl chr 9:98,122,916...98,271,965

G

poly (ADP-ribose) polymerase 1

multiple interactions

[S-Nitroso-N-Acetylpenicillamine results in increased abundance of Nitric Oxide] inhibits the reaction [N-caproylsphingosine promotes the reaction [CASP3 protein results in increased cleavage of PARP1 protein]]

NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404

G

protein kinase C, alpha

multiple interactions

S-Nitroso-N-Acetylpenicillamine promotes the reaction [OPRM1 protein binds to PRKCA protein]

NCBI chr10:92,889,390...93,288,013
Ensembl chr10:92,894,012...93,288,012

G

protein kinase C, gamma

multiple interactions

N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine inhibits the reaction [S-Nitroso-N-Acetylpenicillamine promotes the reaction [OPRM1 protein binds to PRKCG protein]]; S-Nitroso-N-Acetylpenicillamine promotes the reaction [OPRM1 protein binds to PRKCG protein]

PMID:18652891 PMID:21235400

NCBI chr 1:65,832,851...65,860,676
Ensembl chr 1:65,832,855...65,859,384

G

protein kinase cGMP-dependent 1

multiple interactions
increases activity

[S-Nitroso-N-Acetylpenicillamine co-treated with PRKG1 protein alternative form] inhibits the reaction [Phenylephrine results in increased expression of NPPA mRNA]
S-Nitroso-N-Acetylpenicillamine results in increased activity of PRKG1 protein

NCBI chr 1:228,409,605...229,638,794
Ensembl chr 1:228,408,947...229,639,080

G

protein tyrosine phosphatase, non-receptor type 1

increases activity

SNAP increases activity of Ptpn1 protein in aortic smooth muscle cells

RGD

NCBI chr 3:156,638,811...156,687,503
Ensembl chr 3:156,638,769...156,687,504

G

receptor for activated C kinase 1

decreases expression

S-Nitroso-N-Acetylpenicillamine results in decreased expression of RACK1 mRNA

NCBI chr10:33,169,415...33,174,896
Ensembl chr10:33,169,169...33,174,975

G

Raf-1 proto-oncogene, serine/threonine kinase

multiple interactions

S-Nitroso-N-Acetylpenicillamine promotes the reaction [OPRM1 protein binds to RAF1 protein]

NCBI chr 4:148,679,534...148,740,265
Ensembl chr 4:148,679,530...148,740,317

G

regulator of G-protein signaling 17

multiple interactions

S-Nitroso-N-Acetylpenicillamine promotes the reaction [OPRM1 protein binds to RGS17 protein]

NCBI chr 1:42,222,248...42,324,625
Ensembl chr 1:42,227,070...42,324,609

G

ribosomal protein lateral stalk subunit P0

decreases expression

S-Nitroso-N-Acetylpenicillamine results in decreased expression of RPLP0 mRNA

NCBI chr12:41,054,363...41,057,632
Ensembl chr12:41,054,179...41,057,632

G

surfactant protein A1

decreases expression
multiple interactions

S-Nitroso-N-Acetylpenicillamine results in decreased expression of SFTPA1 mRNA
bosentan inhibits the reaction [S-Nitroso-N-Acetylpenicillamine results in decreased expression of SFTPA1 mRNA]; PD 156707 inhibits the reaction [S-Nitroso-N-Acetylpenicillamine results in decreased expression of SFTPA1 mRNA]

NCBI chr16:17,008,180...17,011,686
Ensembl chr16:17,008,180...17,011,685

G

surfactant protein B

multiple interactions
decreases expression

bosentan inhibits the reaction [S-Nitroso-N-Acetylpenicillamine results in decreased expression of SFTPB mRNA]; PD 156707 inhibits the reaction [S-Nitroso-N-Acetylpenicillamine results in decreased expression of SFTPB mRNA]

NCBI chr 4:104,359,303...104,368,439
Ensembl chr 4:104,359,396...104,368,436

G

surfactant protein C

multiple interactions
decreases expression

bosentan inhibits the reaction [S-Nitroso-N-Acetylpenicillamine results in decreased expression of SFTPC mRNA]; PD 156707 inhibits the reaction [S-Nitroso-N-Acetylpenicillamine results in decreased expression of SFTPC mRNA]

NCBI chr15:45,596,565...45,599,615
Ensembl chr15:45,596,574...45,610,777

G

superoxide dismutase 1

multiple interactions
affects response to substance

GPX1 protein affects the reaction [S-Nitroso-N-Acetylpenicillamine promotes the reaction [Diquat results in decreased activity of SOD1 protein]]; S-Nitroso-N-Acetylpenicillamine promotes the reaction [Diquat results in decreased activity of SOD1 protein]
SOD1 protein affects the susceptibility to S-Nitroso-N-Acetylpenicillamine

PMID:10698074 PMID:11672444

NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249

G

superoxide dismutase 2

multiple interactions

GPX1 protein affects the reaction [S-Nitroso-N-Acetylpenicillamine promotes the reaction [Diquat results in increased activity of SOD2 protein]]; S-Nitroso-N-Acetylpenicillamine promotes the reaction [Diquat results in increased activity of SOD2 protein]
[S-Nitroso-N-Acetylpenicillamine results in increased abundance of Nitric Oxide] which results in increased expression of and results in increased activity of SOD2 protein; [S-Nitroso-N-Acetylpenicillamine results in increased abundance of Nitric Oxide] which results in increased expression of SOD2 mRNA

PMID:11672444 PMID:14996425

NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189

G

tumor protein p53

multiple interactions

[S-Nitroso-N-Acetylpenicillamine results in increased abundance of Nitric Oxide] which results in increased expression of TRP53 mRNA
S-Nitroso-N-Acetylpenicillamine promotes the reaction [FGF2 protein results in increased expression of TP53 protein]

PMID:7673702 PMID:16351512

NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524

G

transient receptor potential cation channel, subfamily C, member 6

multiple interactions

S-Nitroso-N-Acetylpenicillamine inhibits the reaction [1-oleoyl-2-acetylglycerol results in increased activity of TRPC6 protein]

NCBI chr 8:5,759,387...5,864,000
Ensembl chr 8:5,758,935...5,828,092

G

vasodilator-stimulated phosphoprotein

increases phosphorylation

S-Nitroso-N-Acetylpenicillamine results in increased phosphorylation of VASP protein

NCBI chr 1:78,910,009...78,925,791
Ensembl chr 1:78,910,011...78,925,061

G

vascular endothelial growth factor A

increases expression
increases secretion

S-Nitroso-N-Acetylpenicillamine results in increased expression of VEGFA mRNA
S-Nitroso-N-Acetylpenicillamine results in increased secretion of VEGFA protein

NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641

Term paths to the root

Path 1
Term	Annotations
CHEBI ontology	19811
role	19818
application	19630
food additive	16107
food acidity regulator	11934
acetic acid	11055
N-acetyl-amino acid	989
N(2)-acetylglutamine +	0
N-acetyl-D-amino acid +	57
N-acetyl-L-amino acid +	964
N-acetyl-S-(1Z)-propenyl-cysteine-sulfoxide	0
N-acetyl-beta-alanine	0
N-acetyl-leucine	0
N-acetylcitrulline +	0
N-acetylglycine +	0
N-acetylhistidine +	0
N-acetylphenylalanine +	0
N-acetyltryptophan	0
N-acetyltyrosine +	0
grixazone A	0
grixazone B	0
Path 2
Term	Annotations
CHEBI ontology	19811
subatomic particle	19809
composite particle	19809
hadron	19840
baryon	19809
nucleon	19809
atomic nucleus	19809
atom	19809
main group element atom	19759
p-block element atom	19759
carbon group element atom	19708
carbon atom	19734
organic molecular entity	19705
heteroorganic entity	19459
organochalcogen compound	19222
organooxygen compound	19137
carbon oxoacid	18597
carboxylic acid	18594
carboacyl group	17675
univalent carboacyl group	17675
carbamoyl group	17524
carboxamide	17547
acetamides	14611
N-acetyl-amino acid	989
N(2)-acetylglutamine +	0
N-acetyl-D-amino acid +	57
N-acetyl-L-amino acid +	964
N-acetyl-S-(1Z)-propenyl-cysteine-sulfoxide	0
N-acetyl-beta-alanine	0
N-acetyl-leucine	0
N-acetylcitrulline +	0
N-acetylglycine +	0
N-acetylhistidine +	0
N-acetylphenylalanine +	0
N-acetyltryptophan	0
N-acetyltyrosine +	0
grixazone A	0
grixazone B	0

paths to the root