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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 734333
Species: Mus musculus
RGD Object: Gene
Symbol: Tgfbr2
Name: transforming growth factor, beta receptor II
Acc ID: CHEBI:28939
Term: N-acetyl-L-cysteine
Definition: An N-acetyl-L-amino acid that is the N-acetylated derivative of the natural amino acid L-cysteine.
Chemical ID: MESH:D000111
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Tgfbr2decreases expressionISOTgfbr2 (Rattus norvegicus)6480464CTDAcetylcysteine results in decreased expression of TGFBR2 mRNA; Acetylcysteine results in decreased expression of TGFBR2 proteinPMID:17602960
Tgfbr2multiple interactionsISOTgfbr2 (Rattus norvegicus)6480464CTDButhionine Sulfoximine inhibits the reaction [Acetylcysteine results in decreased expression of TGFBR2 mRNA]; Buthionine Sulfoximine inhibits the reaction [Acetylcysteine results in decreased expression of TGFBR2 protein]PMID:17602960
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