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Gene: Col1a2 (collagen, type I, alpha 2) Mus musculus
Symbol: Col1a2
Name: collagen, type I, alpha 2
Description: This gene encodes the alpha-2 subunit of the fibril-forming type I collagen, the most abundant protein of bone, skin and tendon extracellular matrices. The encoded protein, in association with alpha-1 subunit, forms heterotrimeric type I procollagen that undergoes proteolytic processing during fibril formation. Mice harboring certain mutations in the encoded gene exhibit symptoms of moderate to severe forms of osteogenesis imperfecta. [provided by RefSeq, Dec 2015]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: AA960264; AI325291; alpha-2 type I collagen; Col1a-2; Cola-2; Cola2; collagen alpha-2(I) chain; collagen COL1A2; oim; osteogenesis imperfecta; procollagen, type I, alpha 2
Homo sapiens (human) : COL1A2 (collagen type I alpha 2 chain)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Col1a2 (collagen type I alpha 2 chain)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Col1a2 (collagen type I alpha 2 chain)
Pan paniscus (bonobo/pygmy chimpanzee) : COL1A2 (collagen type I alpha 2 chain)
Canis lupus familiaris (dog) : COL1A2 (collagen type I alpha 2 chain)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Col1a2 (collagen type I alpha 2 chain)
Sus scrofa (pig) : COL1A2 (collagen type I alpha 2 chain)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm3864,505,618 - 4,541,543 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv3764,455,697 - 4,491,543 (+)NCBIGRCm37mm9NCBIm37
MGSCv3664,455,761 - 4,490,730 (+)NCBImm8
Celera64,648,226 - 4,684,066 (+)NCBICelera
Cytogenetic Map6 A1NCBI
cM Map61.81NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status


Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Col1a2
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 730985
Created: 2003-12-10
Species: Mus musculus
Last Modified: 2019-09-12
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.