Tgfbr1 (transforming growth factor, beta receptor I) - Rat Genome Database

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Gene: Tgfbr1 (transforming growth factor, beta receptor I) Mus musculus
Analyze
Symbol: Tgfbr1
Name: transforming growth factor, beta receptor I
RGD ID: 736083
MGI Page MGI
Description: Exhibits several functions, including SMAD binding activity; transforming growth factor beta binding activity; and transforming growth factor beta-activated receptor activity. Is predicted to contribute to growth factor binding activity. Involved in several processes, including animal organ development; chordate embryonic development; and positive regulation of cellular component organization. Localizes to endosome. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; hemolymphoid system; and sensory organ. Used to study Loeys-Dietz syndrome; osteoarthritis; and systemic scleroderma. Human ortholog(s) of this gene implicated in Ferguson-Smith tumor; Loeys-Dietz syndrome 1; Lynch syndrome; and urinary bladder cancer. Orthologous to human TGFBR1 (transforming growth factor beta receptor 1).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: AL; Alk; Alk-5; ALK5; AU017191; ESK2; Tbet; Tbeta; TbetaR-I; TbetaRI; TGF-beta receptor type I; TGF-beta receptor type-1; TGFR-1; transforming growth factor-beta receptor type I
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39447,353,222 - 47,414,926 (+)NCBIGRCm39mm39
GRCm39 Ensembl447,353,222 - 47,414,931 (+)Ensembl
GRCm38447,353,222 - 47,414,926 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl447,353,222 - 47,414,931 (+)EnsemblGRCm38mm10GRCm38
MGSCv37447,366,177 - 47,427,796 (+)NCBIGRCm37mm9NCBIm37
MGSCv36447,374,405 - 47,436,024 (+)NCBImm8
Celera447,375,763 - 47,437,373 (+)NCBICelera
Cytogenetic Map4B1NCBI
cM Map426.02NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-epigallocatechin 3-gallate  (ISO)
(S)-nicotine  (ISO)
1,2-dichloroethane  (EXP)
1,2-dimethylhydrazine  (EXP)
17beta-estradiol  (ISO)
2,3,3,3-tetrafluoro-2-(heptafluoropropoxy)propanoic acid  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-trinitrobenzenesulfonic acid  (ISO)
2-amino-2-deoxy-D-glucopyranose  (ISO)
3,3'-diindolylmethane  (ISO)
3-methyl-3H-imidazo[4,5-f]quinolin-2-amine  (EXP)
4-hydroxynon-2-enal  (EXP)
4-vinylcyclohexene dioxide  (EXP)
acrolein  (ISO)
aflatoxin B1  (ISO)
aldehydo-D-glucosamine  (ISO)
aldehydo-D-glucose  (ISO)
all-trans-retinoic acid  (EXP,ISO)
all-trans-retinol  (ISO)
allyl alcohol  (ISO)
alpha-pinene  (ISO)
AM-251  (ISO)
ammonium chloride  (ISO)
anthocyanin  (ISO)
benazepril  (ISO)
benzo[a]pyrene  (EXP,ISO)
beta-D-glucosamine  (ISO)
bisphenol A  (EXP,ISO)
bleomycin A2  (EXP,ISO)
cadmium atom  (EXP,ISO)
cadmium dichloride  (ISO)
caffeine  (ISO)
calciol  (EXP)
carbon nanotube  (EXP,ISO)
chlorpyrifos  (EXP)
cisplatin  (ISO)
cocaine  (EXP)
copper atom  (ISO)
copper(0)  (ISO)
corticosterone  (ISO)
coumestrol  (ISO)
crocin-1  (ISO)
curcumin  (ISO)
cyclosporin A  (ISO)
D-glucose  (ISO)
dexamethasone  (EXP)
diazepam  (ISO)
dichlorine  (ISO)
dimethylarsinic acid  (EXP)
enalapril  (ISO)
Enterolactone  (ISO)
ethanol  (EXP,ISO)
ethyl methanesulfonate  (ISO)
flutamide  (ISO)
formaldehyde  (ISO)
furosemide  (ISO)
galangin  (ISO)
glafenine  (ISO)
glucose  (ISO)
glyphosate  (ISO)
hexachlorobenzene  (EXP)
lead(0)  (ISO)
lead(2+)  (ISO)
lenalidomide  (ISO)
leupeptin  (ISO)
lignan  (EXP)
lipopolysaccharide  (ISO)
lithocholic acid  (EXP)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
methamphetamine  (EXP)
methoxychlor  (ISO)
methyl methanesulfonate  (ISO)
Methylazoxymethanol acetate  (ISO)
methylisothiazolinone  (ISO)
methylmercury chloride  (ISO)
mifepristone  (ISO)
N-acetyl-L-cysteine  (ISO)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (ISO)
N-methyl-4-phenylpyridinium  (EXP)
N-nitrosodiethylamine  (EXP,ISO)
N-nitrosodimethylamine  (ISO)
nickel atom  (ISO)
nickel sulfate  (ISO)
nicotine  (ISO)
nitrofen  (ISO)
obeticholic acid  (ISO)
ochratoxin A  (EXP,ISO)
oxalic acid  (ISO)
ozone  (ISO)
paracetamol  (ISO)
paraquat  (ISO)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
phenobarbital  (ISO)
phenylephrine  (ISO)
piperine  (ISO)
potassium chromate  (ISO)
prostaglandin E2  (EXP)
quartz  (ISO)
quercetin  (ISO)
resveratrol  (ISO)
S-butyl-DL-homocysteine (S,R)-sulfoximine  (ISO)
salvianolic acid B  (ISO)
SB 431542  (EXP,ISO)
sodium arsenate  (EXP)
sodium arsenite  (ISO)
streptozocin  (EXP,ISO)
succimer  (EXP)
sulforaphane  (ISO)
sunitinib  (ISO)
tacrolimus hydrate  (ISO)
tamoxifen  (ISO)
tetrachloromethane  (EXP)
tetramethylpyrazine  (EXP)
thalidomide  (ISO)
thioacetamide  (EXP,ISO)
tolfenamic acid  (ISO)
triadimefon  (ISO)
trichostatin A  (ISO)
valproic acid  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
activation of MAPKK activity  (ISO)
activin receptor signaling pathway  (IBA)
aging  (ISO)
angiogenesis  (IMP)
angiogenesis involved in coronary vascular morphogenesis  (IMP)
animal organ regeneration  (ISO)
anterior/posterior pattern specification  (IGI)
apoptotic process  (IEA)
artery morphogenesis  (IMP)
blastocyst development  (IDA)
cell differentiation  (IEA)
cell motility  (ISO)
cellular response to growth factor stimulus  (IBA)
cellular response to transforming growth factor beta stimulus  (IDA,ISO)
collagen fibril organization  (IMP)
coronary artery morphogenesis  (IMP)
digestive tract development  (ISO)
embryo implantation  (ISO)
embryonic cranial skeleton morphogenesis  (IMP)
endothelial cell migration  (IMP)
epicardium morphogenesis  (IMP)
epithelial to mesenchymal transition  (ISO)
germ cell migration  (IMP)
heart development  (IBA,IMP)
in utero embryonic development  (IMP)
kidney development  (IGI)
lens development in camera-type eye  (IMP)
lung development  (ISO)
male gonad development  (IMP)
negative regulation of apoptotic process  (IMP)
negative regulation of chondrocyte differentiation  (IMP)
negative regulation of endothelial cell differentiation  (ISO)
negative regulation of endothelial cell proliferation  (IGI)
negative regulation of extrinsic apoptotic signaling pathway  (ISO)
negative regulation of pri-miRNA transcription by RNA polymerase II  (ISO)
nervous system development  (IBA)
neuron fate commitment  (IMP)
parathyroid gland development  (IMP)
pathway-restricted SMAD protein phosphorylation  (ISO)
peptidyl-serine phosphorylation  (ISO)
peptidyl-threonine phosphorylation  (ISO)
pharyngeal system development  (IMP)
phosphorylation  (IEA)
positive regulation of apoptotic process  (IDA)
positive regulation of apoptotic signaling pathway  (ISO)
positive regulation of cell growth  (ISO)
positive regulation of cell migration  (ISO)
positive regulation of cell population proliferation  (ISO)
positive regulation of cellular component movement  (ISO)
positive regulation of epithelial to mesenchymal transition  (IGI)
positive regulation of epithelial to mesenchymal transition involved in endocardial cushion formation  (IMP)
positive regulation of filopodium assembly  (IMP)
positive regulation of gene expression  (ISO)
positive regulation of pathway-restricted SMAD protein phosphorylation  (ISO)
positive regulation of pri-miRNA transcription by RNA polymerase II  (ISO)
positive regulation of protein kinase B signaling  (ISO)
positive regulation of SMAD protein signal transduction  (ISO)
positive regulation of stress fiber assembly  (IGI)
positive regulation of tight junction disassembly  (IGI)
positive regulation of transcription, DNA-templated  (ISO)
post-embryonic development  (IMP)
proepicardium development  (IMP)
protein autophosphorylation  (ISO)
protein phosphorylation  (IBA,ISO)
regulation of cardiac muscle cell proliferation  (IMP)
regulation of gene expression  (IMP)
regulation of growth  (IEA)
regulation of protein binding  (IMP)
regulation of protein ubiquitination  (ISO)
regulation of transcription, DNA-templated  (ISO)
response to cholesterol  (IDA,ISO)
response to electrical stimulus  (ISO)
response to estrogen  (ISO)
response to hypoxia  (ISO)
response to organic cyclic compound  (ISO)
response to prostaglandin E  (ISO)
response to toxic substance  (ISO)
roof of mouth development  (IGI,IMP)
signal transduction  (ISO)
skeletal system development  (IGI)
skeletal system morphogenesis  (IGI)
thymus development  (IMP)
transforming growth factor beta receptor signaling pathway  (IBA,IDA,IGI,IMP,ISO)
transmembrane receptor protein serine/threonine kinase signaling pathway  (IEA)
ventricular compact myocardium morphogenesis  (IMP)
ventricular septum morphogenesis  (IMP)
ventricular trabecula myocardium morphogenesis  (IMP)

Cellular Component

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
abnormal anal canal morphology  (IAGP)
abnormal angiogenesis  (IAGP)
abnormal aorta bulb morphology  (IAGP)
abnormal aorta elastic fiber morphology  (IAGP)
abnormal aortic arch morphology  (IAGP)
abnormal articular cartilage morphology  (IAGP)
abnormal bronchiole epithelium morphology  (IAGP)
abnormal cartilage development  (IAGP)
abnormal coronary artery morphology  (IAGP)
abnormal lung development  (IAGP)
abnormal neural tube morphology  (IAGP)
abnormal pancreas physiology  (IAGP)
abnormal placenta labyrinth morphology  (IAGP)
abnormal pulmonary alveolus morphology  (IAGP)
abnormal skin development  (IAGP)
abnormal synovial joint morphology  (IAGP)
abnormal type IV hypersensitivity reaction  (IAGP)
abnormal vascular smooth muscle morphology  (IAGP)
abnormal visceral yolk sac morphology  (IAGP)
abnormal vitelline vascular remodeling  (IAGP)
abnormal vitelline vasculature morphology  (IAGP)
absent vitelline blood vessels  (IAGP)
aortic dissection  (IAGP)
ascending aorta aneurysm  (IAGP)
decreased cardiac muscle contractility  (IAGP)
decreased club cell number  (IAGP)
decreased dendritic cell number  (IAGP)
decreased embryo size  (IAGP)
decreased gland tumor incidence  (IAGP)
dilated aorta bulb  (IAGP)
dilated cardiomyopathy  (IAGP)
dilated respiratory conducting tubes  (IAGP)
embryonic growth retardation  (IAGP)
embryonic lethality during organogenesis, complete penetrance  (IAGP)
embryonic lethality, complete penetrance  (IAGP)
enhanced wound healing  (IAGP)
excessive folding of visceral yolk sac  (IAGP)
hemopericardium  (IAGP)
hemothorax  (IAGP)
increased aorta wall thickness  (IAGP)
increased CD8-positive, alpha-beta T cell number  (IAGP)
increased cell proliferation  (IAGP)
increased chondrocyte apoptosis  (IAGP)
increased gastrointestinal tumor incidence  (IAGP)
increased hematopoietic stem cell proliferation  (IAGP)
increased intestinal adenocarcinoma incidence  (IAGP)
increased oral papilloma incidence  (IAGP)
increased organ/body region tumor incidence  (IAGP)
increased pancreas tumor incidence  (IAGP)
increased papilloma incidence  (IAGP)
increased squamous cell carcinoma incidence  (IAGP)
kinked neural tube  (IAGP)
kyphosis  (IAGP)
neonatal lethality, complete penetrance  (IAGP)
no abnormal phenotype detected  (IAGP)
osteoarthritis  (IAGP)
osteophytes  (IAGP)
pericardial effusion  (IAGP)
premature coronal suture closure  (IAGP)
premature cranial suture closure  (IAGP)
premature death  (IAGP)
premature lambdoid suture closure  (IAGP)
prenatal lethality, complete penetrance  (IAGP)
preweaning lethality, complete penetrance  (IEA)
small lung  (IAGP)
References

References - curated
1. Akool el-S, etal., J Immunol. 2008 Aug 15;181(4):2831-45.
2. Asano Y, etal., J Clin Invest. 2004 Jan;113(2):253-64.
3. Bassing CH, etal., Science 1994 Jan 7;263(5143):87-9.
4. Bonecini-Almeida MG, etal., Infect Immun. 2004 May;72(5):2628-34.
5. Chen T, etal., Clin Cancer Res. 2006 Jan 15;12(2):392-7.
6. Chen T, etal., Int J Cancer. 2004 Nov 10;112(3):420-5.
7. Chen Y, etal., Am J Pathol. 2005 Dec;167(6):1699-711.
8. de Gouville AC, etal., Br J Pharmacol. 2005 May;145(2):166-77.
9. Frazier K, etal., Toxicol Pathol. 2007;35(2):284-95.
10. Gordon KJ and Blobe GC, Biochim Biophys Acta. 2008 Apr;1782(4):197-228. Epub 2008 Feb 11.
11. Hao J, etal., J Mol Cell Cardiol. 1999 Mar;31(3):667-78.
12. Hartner A, etal., J Mol Med. 2003 Jan;81(1):32-42. Epub 2002 Dec 14.
13. Hattori K, etal., Carcinogenesis. 1997 Oct;18(10):1867-70.
14. Jude EB, etal., Diabet Med. 2002 Jun;19(6):440-7.
15. Kawai J, etal., Nature. 2001 Feb 8;409(6821):685-90.
16. Khalil N, etal., Exp Lung Res. 2002 Apr-May;28(3):233-50.
17. Ko MS, etal., Development 2000 Apr;127(8):1737-49.
18. Laping NJ, etal., Clin Cancer Res. 2007 May 15;13(10):3087-99.
19. Loeys BL, etal., Nat Genet. 2005 Mar;37(3):275-81. Epub 2005 Jan 30.
20. MGD and Homologene mouse data transfer
21. MGD data from the GO Consortium
22. MGD IEA
23. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
24. OMIM Disease Annotation Pipeline
25. Pipeline to import KEGG annotations from KEGG into RGD
26. Pipeline to import Pathway Interaction Database annotations from NCI into RGD
27. Ranchoux B, etal., Circulation. 2015 Mar 17;131(11):1006-18. doi: 10.1161/CIRCULATIONAHA.114.008750. Epub 2015 Jan 15.
28. RGD automated import pipeline
29. RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
30. RGD automated import pipeline for gene-chemical interactions
31. Shi Y and Massague J, Cell. 2003 Jun 13;113(6):685-700.
32. Siegel PM, etal., Proc Natl Acad Sci U S A 2003 Jul 8;100(14):8430-5. Epub 2003 Jun 13.
33. Wang XN, etal., Zhong Xi Yi Jie He Xue Bao. 2005 Jul;3(4):286-9.
34. Wilkes MC, etal., Mol Cell Biol. 2003 Dec;23(23):8878-89.
35. Woszczyk D, etal., Med Sci Monit. 2004 Jan;10(1):CR33-7.
36. Xu Y and Pasche B, Hum Mol Genet. 2007 Apr 15;16 Spec No 1:R14-20.
37. Zaiman AL, etal., Am J Respir Crit Care Med. 2008 Apr 15;177(8):896-905. Epub 2008 Jan 17.
38. Zhang X, etal., J Neurogastroenterol Motil. 2016 Apr 30;22(2):333-43. doi: 10.5056/jnm15127.
39. Zhang Y, etal., Zhongguo Zhong Xi Yi Jie He Za Zhi. 2007 Dec;27(12):1094-8.
Additional References at PubMed
PMID:7641785   PMID:7813789   PMID:8117261   PMID:8117262   PMID:8140412   PMID:8268187   PMID:8605036   PMID:8883836   PMID:9434964   PMID:9449696   PMID:9856985   PMID:9879710  
PMID:9921650   PMID:10030593   PMID:10349636   PMID:10433915   PMID:10521784   PMID:10885742   PMID:10949049   PMID:11042159   PMID:11076861   PMID:11285230   PMID:11544199   PMID:11641223  
PMID:11675471   PMID:11850179   PMID:12047746   PMID:12070302   PMID:12391023   PMID:12477932   PMID:12520002   PMID:12546816   PMID:12588999   PMID:12666204   PMID:12773577   PMID:12838410  
PMID:12842983   PMID:14580334   PMID:14610273   PMID:14681479   PMID:14729481   PMID:14764882   PMID:14996829   PMID:15142957   PMID:15239668   PMID:15247277   PMID:15342483   PMID:15350225  
PMID:15376321   PMID:15459394   PMID:15489334   PMID:15548578   PMID:15657037   PMID:15744664   PMID:15761148   PMID:15761153   PMID:15769904   PMID:15820682   PMID:15850837   PMID:15963767  
PMID:15976303   PMID:15993878   PMID:16141072   PMID:16141073   PMID:16344855   PMID:16601693   PMID:16602821   PMID:16806156   PMID:16845371   PMID:17071858   PMID:17078885   PMID:17126294  
PMID:17168649   PMID:17197570   PMID:17274978   PMID:17418116   PMID:17530030   PMID:17530708   PMID:17534148   PMID:17634193   PMID:17657819   PMID:17673906   PMID:17878231   PMID:17911384  
PMID:17977532   PMID:18005957   PMID:18029401   PMID:18095342   PMID:18252868   PMID:18257072   PMID:18287559   PMID:18310502   PMID:18316594   PMID:18337748   PMID:18438410   PMID:18469808  
PMID:18474439   PMID:18474728   PMID:18572160   PMID:18586087   PMID:18625725   PMID:18676816   PMID:18718461   PMID:18796535   PMID:18804439   PMID:18821589   PMID:18832392   PMID:18945958  
PMID:18990706   PMID:19096363   PMID:19147584   PMID:19165826   PMID:19398875   PMID:19398960   PMID:19462458   PMID:19494318   PMID:19501582   PMID:19520971   PMID:19531477   PMID:19538749  
PMID:19556242   PMID:19561097   PMID:19580641   PMID:19584284   PMID:19619490   PMID:19653094   PMID:19679673   PMID:19757385   PMID:19951995   PMID:20042635   PMID:20147383   PMID:20171187  
PMID:20346356   PMID:20436479   PMID:20471380   PMID:20572855   PMID:20603020   PMID:20607716   PMID:20713882   PMID:20962846   PMID:21062784   PMID:21127043   PMID:21131965   PMID:21266196  
PMID:21267068   PMID:21282335   PMID:21297643   PMID:21402782   PMID:21491542   PMID:21518866   PMID:21530805   PMID:21537080   PMID:21593423   PMID:21604321   PMID:21731673   PMID:21832243  
PMID:21841138   PMID:21852401   PMID:21873635   PMID:21876535   PMID:21947380   PMID:21984393   PMID:21998450   PMID:22028666   PMID:22037217   PMID:22202673   PMID:22326956   PMID:22388934  
PMID:22399812   PMID:22451679   PMID:22485132   PMID:22498737   PMID:22560297   PMID:22584670   PMID:22706160   PMID:22773947   PMID:22859719   PMID:23065670   PMID:23103542   PMID:23213481  
PMID:23248173   PMID:23307286   PMID:23340180   PMID:23342175   PMID:23546880   PMID:23562608   PMID:23565059   PMID:23624079   PMID:23661518   PMID:23712751   PMID:23770676   PMID:23770987  
PMID:23831617   PMID:23868260   PMID:23918385   PMID:23946447   PMID:23950180   PMID:24088962   PMID:24089514   PMID:24124460   PMID:24127404   PMID:24279395   PMID:24324142   PMID:24344132  
PMID:24347165   PMID:24355923   PMID:24474796   PMID:24506537   PMID:24515103   PMID:24573206   PMID:24587008   PMID:24590287   PMID:24760528   PMID:24817606   PMID:24835278   PMID:24859004  
PMID:24859199   PMID:24912677   PMID:24952961   PMID:25002492   PMID:25065622   PMID:25204661   PMID:25266657   PMID:25382630   PMID:25406396   PMID:25421310   PMID:25429440   PMID:25467979  
PMID:25505200   PMID:25720380   PMID:25722190   PMID:25723392   PMID:25849774   PMID:25885904   PMID:26053644   PMID:26081042   PMID:26120030   PMID:26138667   PMID:26138704   PMID:26151572  
PMID:26202810   PMID:26305969   PMID:26322481   PMID:26418219   PMID:26496610   PMID:26657345   PMID:26680585   PMID:26692002   PMID:26980767   PMID:26984772   PMID:27020852   PMID:27180663  
PMID:27235139   PMID:27318131   PMID:27344183   PMID:27418101   PMID:27453501   PMID:27573189   PMID:27739498   PMID:27798955   PMID:27824055   PMID:27826032   PMID:27866969   PMID:27892604  
PMID:27923978   PMID:27997889   PMID:28095798   PMID:28145440   PMID:28168444   PMID:28368414   PMID:28423340   PMID:28518142   PMID:28622298   PMID:28657664   PMID:28662367   PMID:28716756  
PMID:28747781   PMID:28759052   PMID:28811219   PMID:28845554   PMID:28924218   PMID:28931816   PMID:28945245   PMID:29031500   PMID:29047105   PMID:29190781   PMID:29343501   PMID:29440304  
PMID:29456135   PMID:29572483   PMID:29588073   PMID:29788434   PMID:30078186   PMID:30100246   PMID:30111642   PMID:30230540   PMID:30459156   PMID:30655341   PMID:30660362   PMID:30718289  
PMID:30929801   PMID:31071011   PMID:31142541   PMID:31144525   PMID:31173246   PMID:31273920   PMID:31311317   PMID:31311865   PMID:31400222   PMID:31402170   PMID:31437169   PMID:31526760  
PMID:31845233   PMID:31845891   PMID:32001436   PMID:32065217   PMID:32274860   PMID:32319652   PMID:32404924   PMID:32535034   PMID:32597756   PMID:32902612  


Genomics

Comparative Map Data
Tgfbr1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39447,353,222 - 47,414,926 (+)NCBIGRCm39mm39
GRCm39 Ensembl447,353,222 - 47,414,931 (+)Ensembl
GRCm38447,353,222 - 47,414,926 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl447,353,222 - 47,414,931 (+)EnsemblGRCm38mm10GRCm38
MGSCv37447,366,177 - 47,427,796 (+)NCBIGRCm37mm9NCBIm37
MGSCv36447,374,405 - 47,436,024 (+)NCBImm8
Celera447,375,763 - 47,437,373 (+)NCBICelera
Cytogenetic Map4B1NCBI
cM Map426.02NCBI
TGFBR1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl999,104,038 - 99,154,192 (+)EnsemblGRCh38hg38GRCh38
GRCh38999,104,038 - 99,154,192 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh379101,867,395 - 101,916,474 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 369100,907,233 - 100,956,295 (+)NCBINCBI36hg18NCBI36
Build 34998,946,966 - 98,991,862NCBI
Celera972,381,280 - 72,430,335 (+)NCBI
Cytogenetic Map9q22.33NCBI
HuRef971,464,684 - 71,515,132 (+)NCBIHuRef
CHM1_19102,013,810 - 102,062,916 (+)NCBICHM1_1
Tgfbr1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2561,653,773 - 61,710,777 (+)NCBI
Rnor_6.0 Ensembl563,050,758 - 63,119,635 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0563,056,071 - 63,119,635 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.0569,079,391 - 69,097,816 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
Rnor_5.0567,575,578 - 67,643,666 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4563,976,868 - 64,034,058 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1563,981,949 - 64,034,967 (+)NCBI
Celera565,882,184 - 65,907,477 (-)NCBICelera
Cytogenetic Map5q22NCBI
Tgfbr1
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541926,490,899 - 26,547,017 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541926,490,899 - 26,546,349 (-)NCBIChiLan1.0ChiLan1.0
TGFBR1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1998,337,417 - 98,362,748 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl998,332,739 - 98,362,748 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0970,195,007 - 70,243,514 (+)NCBIMhudiblu_PPA_v0panPan3
TGFBR1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11156,191,383 - 56,223,042 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1156,161,772 - 56,218,594 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1154,594,299 - 54,654,173 (+)NCBI
ROS_Cfam_1.01157,272,690 - 57,331,474 (+)NCBI
UMICH_Zoey_3.11155,775,923 - 55,835,949 (+)NCBI
UNSW_CanFamBas_1.01155,800,862 - 55,860,799 (+)NCBI
UU_Cfam_GSD_1.01156,499,979 - 56,559,879 (+)NCBI
Tgfbr1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947171,109,141 - 171,133,324 (+)NCBI
SpeTri2.0NW_0049365247,656,523 - 7,680,043 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TGFBR1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1240,859,270 - 240,918,528 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11240,842,735 - 240,918,267 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21269,090,577 - 269,149,183 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TGFBR1
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11240,272,507 - 40,321,740 (-)NCBI
ChlSab1.1 Ensembl1240,276,916 - 40,297,372 (-)Ensembl
Tgfbr1
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248251,773,158 - 1,899,120 (-)NCBI

Position Markers
AU017191  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38447,383,892 - 47,384,019UniSTSGRCm38
MGSCv37447,396,764 - 47,396,891UniSTSGRCm37
Celera447,406,359 - 47,406,486UniSTS
Cytogenetic Map4B1UniSTS
cM Map419.3UniSTS
Whitehead/MRC_RH4743.27UniSTS
D25540  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38447,411,304 - 47,411,433UniSTSGRCm38
MGSCv37447,424,176 - 47,424,305UniSTSGRCm37
Celera447,433,753 - 47,433,882UniSTS
Cytogenetic Map4B1UniSTS
cM Map419.3UniSTS
Whitehead/MRC_RH4744.2UniSTS
Tgfbr1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
MGSCv37447,424,507 - 47,424,710UniSTSGRCm37
MGSCv37447,418,406 - 47,418,509UniSTSGRCm37
Celera447,427,983 - 47,428,086UniSTS
Celera447,434,084 - 47,434,287UniSTS
Cytogenetic Map4B1UniSTS
cM Map419.3UniSTS
cM Map419.3UniSTS
38.MMHAP32FLE5.seq  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38447,355,801 - 47,355,969UniSTSGRCm38
MGSCv37447,368,673 - 47,368,841UniSTSGRCm37
Celera447,378,263 - 47,378,431UniSTS
Cytogenetic Map4B1UniSTS
cM Map419.3UniSTS
Whitehead_YAC4 UniSTS
PMC145465P1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38447,392,934 - 47,393,084UniSTSGRCm38
MGSCv37447,405,806 - 47,405,956UniSTSGRCm37
Celera447,415,403 - 47,415,553UniSTS
Cytogenetic Map4B1UniSTS
cM Map419.3UniSTS
Tgfbr1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38447,411,635 - 47,411,838UniSTSGRCm38
MGSCv37447,424,507 - 47,424,710UniSTSGRCm37
Celera447,434,084 - 47,434,287UniSTS
Cytogenetic Map4B1UniSTS
cM Map419.3UniSTS
Tgfbr1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38447,405,534 - 47,405,637UniSTSGRCm38
MGSCv37447,418,406 - 47,418,509UniSTSGRCm37
Celera447,427,983 - 47,428,086UniSTS
Cytogenetic Map4B1UniSTS
Tgfbr1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map4B1UniSTS
Tgfbr1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map4B1UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
11567249Elorr3_methanol induced loss of righting response 3 (mouse)43722677156183778Mouse
4142318Lyr2_mlymphoma resistance 2 (mouse)Not determined1401045763365441Mouse
4142047Mvwf3_mmodifier of von Willebrand factor 3 (mouse)Not determined14010457117215009Mouse
1301203Alcp8_malcohol preference locus 8 (mouse)Not determined41739516051395290Mouse
1301237Alcp7_malcohol preference locus 7 (mouse)Not determined41739516051395290Mouse
4141555Nbwa2_mNZB and NZW autoimmunity 2 (mouse)Not determined41789251551892635Mouse
4141911W6q15_mweight 6 weeks QTL 15 (mouse)Not determined1789261689063979Mouse
1357645Lvrq9_mliver weight QTL 9 (mouse)Not determined41789261689063979Mouse
1357453Kidq4_mkidney weight QTL 4 (mouse)Not determined41789261689063979Mouse
39128211Lwq22_mliver weight QTL 22 (mouse)41789261689063979Mouse
1300769Pcyts2_mplasmacytoma susceptibility 2 (mouse)Not determined42211194456112145Mouse
1302058Hrtfm3_mheart failure modifier 3 (mouse)Not determined42211194456112145Mouse
1302075Bdln6_mbody length 6 (mouse)Not determined42237344856373612Mouse
1301437Scon1_msucrose consumption 1 (mouse)Not determined42237344856373612Mouse
1301697Sluc18_msusceptibility to lung cancer 18 (mouse)Not determined42237344856373612Mouse
1300574Im2_mimmunoregulatory 2 (mouse)Not determined42807768262077816Mouse
1301586Stheal3_msoft tissue heal 3 (mouse)Not determined42865844262658566Mouse
1357877Synch1_msynechia 1 (mouse)Not determined42870992562710107Mouse
1301990Arvm1_mautoimmune renal vasculitis 1 (mouse)Not determined42933264663332776Mouse
1301792Hdlq10_mHDL QTL 10 (mouse)Not determined43585970769859853Mouse
1300977Mopkd1_mmodifier of polycystic kidney disease progression 1 (mouse)Not determined43655083970550967Mouse
26884449Sklq2_mskull length QTL 2, 5 week (mouse)436700000129100000Mouse
1302116Bbaa1_mB.burgdorferi-associated arthritis 1 (mouse)Not determined43825093072251078Mouse
10412178Habiir2_mhyperoxic acute lung injury imprinted region 2 (mouse)Not determined43945212663365441Mouse
1301786Bpq3_mblood pressure QTL 3 (mouse)Not determined44240224076402381Mouse
27226724Tibw2_mtibia width 2, proximal, 10 week (mouse)443000000108500000Mouse
1301941Mmtg1_mmodifier of mammary tumor growth 1 (mouse)Not determined44565844283180920Mouse
1558948Ath8_matherosclerosis 8 (mouse)Not determined445658442105299798Mouse
1357895Ctrcts_mcataract severity (mouse)Not determined445709925138615442Mouse
1558794Agnm1_mautoimmune glomerulonephritis in MRL 1 (mouse)Not determined44633264655755867Mouse
1300966Pabr2_mplasma apolipoprotein B (human) regulator 2 (mouse)Not determined446332646105944663Mouse
10043880Adip23_madiposity 23 (mouse)Not determined44636529480365441Mouse
12879977Bod2_mbone length and organs 2 (mouse)44636529480365441Mouse
11532714Sluc43_msusceptibility to lung cancer 43 (mouse)446642108123233418Mouse
10449022Aanq1_maristolochic acid nephrotoxicity QTL 1 (mouse)44668558980685589Mouse

miRNA Target Status

Confirmed Target Of
miRNA GeneMature miRNAMethod NameResult TypeData TypeSupport TypePMID
Mir128-2mmu-miR-128-3pOncomiRDBexternal_infoNANA20054641
Mir128-1mmu-miR-128-3pOncomiRDBexternal_infoNANA20054641
Mir122mmu-miR-122-5pMirtarbaseexternal_infoLuciferase reporter assay//Reporter assay;qRT-PCR;Functional MTI19487572
Mir140mmu-miR-140-5pOncomiRDBexternal_infoNANA23401231

Predicted Target Of
Summary Value
Count of predictions:2244
Count of miRNA genes:716
Interacting mature miRNAs:927
Transcripts:ENSMUST00000007757, ENSMUST00000044234, ENSMUST00000107725, ENSMUST00000123962, ENSMUST00000126171
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001312868 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001312869 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_009370 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_030253397 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_036163955 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AK007125 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK015337 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK153796 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK154381 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL772150 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL772232 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC063260 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BY200044 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466565 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CK637995 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CT010393 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D25540 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D28526 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FB746001 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000007757   ⟹   ENSMUSP00000007757
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl447,353,222 - 47,414,931 (+)Ensembl
RefSeq Acc Id: ENSMUST00000044234   ⟹   ENSMUSP00000048501
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl447,353,307 - 47,412,133 (+)Ensembl
RefSeq Acc Id: ENSMUST00000107725   ⟹   ENSMUSP00000103353
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl447,386,216 - 47,411,035 (+)Ensembl
RefSeq Acc Id: ENSMUST00000123962
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl447,353,598 - 47,361,313 (+)Ensembl
RefSeq Acc Id: ENSMUST00000126171   ⟹   ENSMUSP00000123761
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl447,353,610 - 47,410,807 (+)Ensembl
RefSeq Acc Id: NM_001312868   ⟹   NP_001299797
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39447,353,222 - 47,414,924 (+)NCBI
GRCm38447,353,222 - 47,414,924 (+)NCBI
Sequence:
RefSeq Acc Id: NM_001312869   ⟹   NP_001299798
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39447,386,216 - 47,414,924 (+)NCBI
GRCm38447,386,216 - 47,414,924 (+)NCBI
Sequence:
RefSeq Acc Id: NM_009370   ⟹   NP_033396
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39447,353,222 - 47,414,924 (+)NCBI
GRCm38447,353,222 - 47,414,924 (+)NCBI
MGSCv37447,366,177 - 47,427,796 (+)RGD
Celera447,375,763 - 47,437,373 (+)RGD
cM Map4 ENTREZGENE
Sequence:
RefSeq Acc Id: XM_030253397   ⟹   XP_030109257
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39447,353,222 - 47,414,926 (+)NCBI
GRCm38447,353,222 - 47,414,926 (+)NCBI
Sequence:
RefSeq Acc Id: XM_036163955   ⟹   XP_036019848
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39447,353,599 - 47,414,926 (+)NCBI
Reference Sequences
RefSeq Acc Id: NP_033396   ⟸   NM_009370
- Peptide Label: isoform 1 precursor
- UniProtKB: Q64729 (UniProtKB/Swiss-Prot),   Q4FJL1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001299797   ⟸   NM_001312868
- Peptide Label: isoform 2 precursor
- UniProtKB: Q64729 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001299798   ⟸   NM_001312869
- Peptide Label: isoform 3
- UniProtKB: Q64729 (UniProtKB/Swiss-Prot),   Q9D5H8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_030109257   ⟸   XM_030253397
- Peptide Label: isoform X2
RefSeq Acc Id: ENSMUSP00000007757   ⟸   ENSMUST00000007757
RefSeq Acc Id: ENSMUSP00000103353   ⟸   ENSMUST00000107725
RefSeq Acc Id: ENSMUSP00000123761   ⟸   ENSMUST00000126171
RefSeq Acc Id: ENSMUSP00000048501   ⟸   ENSMUST00000044234
RefSeq Acc Id: XP_036019848   ⟸   XM_036163955
- Peptide Label: isoform X1
Protein Domains
GS   Protein kinase

Promoters
RGD ID:6883376
Promoter ID:EPDNEW_M5139
Type:initiation region
Name:Tgfbr1_1
Description:Mus musculus transforming growth factor, beta receptor I , transcriptvariant 3, mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38447,353,291 - 47,353,351EPDNEW
RGD ID:6836501
Promoter ID:MM_KWN:37549
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:3T3L1_Day0,   3T3L1_Day1,   3T3L1_Day2,   3T3L1_Day3,   BoneMarrow_0Hour,   BoneMarrow_2Hour,   BoneMarrow_4Hour,   Brain,   ES_Cell,   Kidney,   Liver,   Lung,   MEF_B4,   MEF_B6,   Spleen
Transcripts:OTTMUST00000015672,   OTTMUST00000015675,   OTTMUST00000015676,   UC008SUO.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36447,365,676 - 47,366,217 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:98728 AgrOrtholog
Ensembl Genes ENSMUSG00000007613 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000007757 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000048501 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000103353 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUSP00000123761 ENTREZGENE, UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000007757 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000044234 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000107725 ENTREZGENE, UniProtKB/TrEMBL
  ENSMUST00000126171 ENTREZGENE, UniProtKB/TrEMBL
InterPro Activin_recp UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GS_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Kinase-like_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Prot_kinase_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Protein_kinase_ATP_BS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ser/Thr_kinase_AS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TGFB_receptor UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:21812 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:98728 ENTREZGENE
NCBI Gene 21812 ENTREZGENE
PANTHER PTHR23255 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Activin_recp UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Pkinase UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TGF_beta_GS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Tgfbr1 PhenoGen
PROSITE PROTEIN_KINASE_ATP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PROTEIN_KINASE_DOM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PROTEIN_KINASE_ST UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PS51256 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART S_TKc UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SM00467 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF56112 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt E9Q418_MOUSE UniProtKB/TrEMBL
  Q3U485_MOUSE UniProtKB/TrEMBL
  Q4FJL1 ENTREZGENE, UniProtKB/TrEMBL
  Q64729 ENTREZGENE
  Q9CVP4_MOUSE UniProtKB/TrEMBL
  Q9D5H8 ENTREZGENE, UniProtKB/TrEMBL
  TGFR1_MOUSE UniProtKB/Swiss-Prot
UniProt Secondary A2AJN0 UniProtKB/Swiss-Prot