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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 736083
Species: Mus musculus
RGD Object: Gene
Symbol: Tgfbr1
Name: transforming growth factor, beta receptor I
Acc ID: CHEBI:6426
Term: leupeptin
Definition: A tripeptide composed of N-acetylleucyl, leucyl and argininal residues joined in sequenceby peptide linkages. It is an inhibitor of the calpains, a family of calcium-activated proteases which promote cell death.
Chemical ID: MESH:C032854
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Tgfbr1increases expressionISOTgfbr1 (Rattus norvegicus)6480464CTDleupeptin results in increased expression of TGFBR1 proteinPMID:27826032
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