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Gene: Ireb2 (iron responsive element binding protein 2) Mus musculus
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Symbol: Ireb2
Name: iron responsive element binding protein 2
Description: Exhibits iron-responsive element binding activity. Involved in several processes, including intestinal absorption; osteoclast differentiation; and protoporphyrinogen IX biosynthetic process. Localizes to cytosol. Human ortholog(s) of this gene implicated in Alzheimer's disease. Is expressed in several structures, including nervous system and yolk sac. Orthologous to human IREB2 (iron responsive element binding protein 2); PARTICIPATES IN doxorubicin response pathway; iron homeostasis pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; benzo[a]pyrene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: D9Ertd85e; DKFZp564D1164; IRE-BP 2; iron regulatory protein 2; iron-responsive element-binding protein 2; Irp2
Orthologs:
Homo sapiens (human) : IREB2 (iron responsive element binding protein 2)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Ireb2 (iron responsive element binding protein 2)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ireb2 (iron responsive element binding protein 2)
Pan paniscus (bonobo/pygmy chimpanzee) : IREB2 (iron responsive element binding protein 2)
Canis lupus familiaris (dog) : IREB2 (iron responsive element binding protein 2)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ireb2 (iron responsive element binding protein 2)
Sus scrofa (pig) : IREB2 (iron responsive element binding protein 2)
Chlorocebus sabaeus (African green monkey) : IREB2 (iron responsive element binding protein 2)
Heterocephalus glaber (naked mole-rat) : Ireb2 (iron responsive element binding protein 2)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl954,863,789 - 54,912,530 (+)EnsemblGRCm38mm10GRCm38
GRCm38954,862,658 - 54,912,534 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37954,711,562 - 54,760,341 (+)NCBIGRCm37mm9NCBIm37
MGSCv36954,661,926 - 54,708,169 (+)NCBImm8
Celera952,108,353 - 52,158,699 (+)NCBICelera
Cytogenetic Map9BNCBI
cM Map929.81NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Ireb2
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 736754
Created: 2004-02-06
Species: Mus musculus
Last Modified: 2020-05-05
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.