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Gene: Angpt1 (angiopoietin 1) Mus musculus
Symbol: Angpt1
Name: angiopoietin 1
Description: Exhibits signaling receptor binding activity. Involved in several processes, including negative regulation of protein transport; regulation of protein phosphorylation; and regulation of signal transduction. Predicted to localize to several cellular components, including the extracellular space; membrane raft; and microvillus. Human ortholog(s) of this gene implicated in brain ischemia; diabetic retinopathy; and hypertension. Is expressed in several structures, including cardiovascular system; liver; lung; metanephros; and yolk sac. Orthologous to human ANGPT1 (angiopoietin 1).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 1110046O21Rik; Ang-1; Ang1; angiopoietin-1
Homo sapiens (human) : ANGPT1 (angiopoietin 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Angpt1 (angiopoietin 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Angpt1 (angiopoietin 1)
Pan paniscus (bonobo/pygmy chimpanzee) : ANGPT1 (angiopoietin 1)
Canis lupus familiaris (dog) : ANGPT1 (angiopoietin 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Angpt1 (angiopoietin 1)
Sus scrofa (pig) : ANGPT1 (angiopoietin 1)
Chlorocebus sabaeus (green monkey) : ANGPT1 (angiopoietin 1)
Heterocephalus glaber (naked mole-rat) : Angpt1 (angiopoietin 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1542,424,723 - 42,676,977 (-)Ensembl
GRCm381542,424,667 - 42,676,977 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371542,256,269 - 42,508,341 (-)NCBIGRCm37mm9NCBIm37
MGSCv361542,254,797 - 42,506,869 (-)NCBImm8
Celera1542,923,745 - 43,172,815 (-)NCBICelera
Cytogenetic Map15 B3.1NCBI
cM Map1516.69NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Angpt1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1551549
Created: 2005-09-30
Species: Mus musculus
Last Modified: 2020-01-28
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.