1,1-dichloroethene decreases expression EXP 6480464 vinylidene chloride results in decreased expression of ANGPT1 mRNA CTD PMID:26682919 17beta-estradiol decreases expression ISO RGD:733136 6480464 Estradiol results in decreased expression of ANGPT1 mRNA CTD PMID:16705744 17beta-estradiol multiple interactions ISO RGD:733136 6480464 [Estradiol co-treated with Progesterone] results in increased expression of ANGPT1 mRNA, [Estradiol co-treated with TGFB1 protein] results in decreased expression of ANGPT1 mRNA CTD PMID:20660070 , PMID:30165855 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of ANGPT1 mRNA CTD PMID:16120747 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:628896 6480464 Tetrachlorodibenzodioxin results in increased expression of ANGPT1 mRNA CTD PMID:24475139 3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine increases expression ISO RGD:628896 6480464 Puromycin Aminonucleoside results in increased expression of ANGPT1 mRNA CTD PMID:17667850 3,3',5,5'-tetrabromobisphenol A decreases expression EXP 6480464 tetrabromobisphenol A results in decreased expression of ANGPT1 mRNA CTD PMID:25172293 3-chloropropane-1,2-diol increases expression ISO RGD:628896 6480464 alpha-Chlorohydrin results in increased expression of ANGPT1 mRNA CTD PMID:28522335 3-isobutyl-1-methyl-7H-xanthine multiple interactions ISO RGD:733136 6480464 [Dexamethasone co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of ANGPT1 mRNA, [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin] results in increased expression of ANGPT1 mRNA CTD PMID:16997883 , PMID:28628672 4,4'-sulfonyldiphenol increases expression EXP 6480464 bis(4-hydroxyphenyl)sulfone results in increased expression of ANGPT1 mRNA CTD PMID:30951980 4-hydroxyphenyl retinamide decreases expression EXP 6480464 Fenretinide results in decreased expression of ANGPT1 mRNA CTD PMID:28973697 5-fluorouracil multiple interactions ISO RGD:733136 6480464 ANGPT1 protein promotes the reaction [Fluorouracil results in increased expression of IFNA1 protein] CTD PMID:17786339 5-fluorouracil increases expression ISO RGD:733136 6480464 Fluorouracil results in increased expression of ANGPT1 protein CTD PMID:17786339 6-propyl-2-thiouracil increases expression ISO RGD:628896 6480464 Propylthiouracil results in increased expression of ANGPT1 mRNA CTD PMID:24780913 8-Br-cAMP multiple interactions ISO RGD:733136 6480464 [Dexamethasone co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of ANGPT1 mRNA CTD PMID:16997883 aflatoxin B1 affects expression ISO RGD:733136 6480464 Aflatoxin B1 affects the expression of ANGPT1 protein CTD PMID:20106945 aflatoxin B1 decreases expression ISO RGD:733136 6480464 Aflatoxin B1 results in decreased expression of ANGPT1 mRNA CTD PMID:22100608 all-trans-retinoic acid increases expression ISO RGD:733136 6480464 Tretinoin results in increased expression of ANGPT1 mRNA CTD PMID:21934132 ammonium chloride affects expression ISO RGD:628896 6480464 Ammonium Chloride affects the expression of ANGPT1 mRNA CTD PMID:16483693 antirheumatic drug decreases expression ISO RGD:733136 6480464 Antirheumatic Agents results in decreased expression of ANGPT1 mRNA CTD PMID:24449571 arsane decreases expression EXP 6480464 Arsenic results in decreased expression of ANGPT1 mRNA CTD PMID:19654921 arsane affects expression ISO RGD:733136 6480464 Arsenic affects the expression of ANGPT1 protein CTD PMID:24675094 arsenic atom decreases expression EXP 6480464 Arsenic results in decreased expression of ANGPT1 mRNA CTD PMID:19654921 arsenic atom affects expression ISO RGD:733136 6480464 Arsenic affects the expression of ANGPT1 protein CTD PMID:24675094 arsenous acid decreases expression ISO RGD:733136 6480464 Arsenic Trioxide results in decreased expression of ANGPT1 mRNA CTD PMID:20458559 belinostat increases expression ISO RGD:733136 6480464 belinostat results in increased expression of ANGPT1 mRNA CTD PMID:26272509 belinostat multiple interactions ISO RGD:733136 6480464 [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ANGPT1 mRNA CTD PMID:27188386 benzo[a]pyrene decreases expression EXP 6480464 Benzo(a)pyrene results in decreased expression of ANGPT1 mRNA CTD PMID:22228805 bisphenol A multiple interactions ISO RGD:628896 6480464 [bisphenol A co-treated with Testosterone] results in decreased expression of ANGPT1 mRNA CTD PMID:26496021 bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of ANGPT1 mRNA CTD PMID:30951980 bisphenol A increases methylation ISO RGD:628896 6480464 bisphenol A results in increased methylation of ANGPT1 gene CTD PMID:28505145 bisphenol A decreases expression ISO RGD:628896 6480464 bisphenol A results in decreased expression of ANGPT1 mRNA CTD PMID:30816183 bisphenol A decreases expression ISO RGD:733136 6480464 bisphenol A results in decreased expression of ANGPT1 mRNA CTD PMID:27685785 bisphenol A affects expression ISO RGD:628896 6480464 bisphenol A affects the expression of ANGPT1 mRNA CTD PMID:25181051 bisphenol F increases expression EXP 6480464 bisphenol F results in increased expression of ANGPT1 mRNA CTD PMID:30951980 cadmium dichloride increases expression ISO RGD:733136 6480464 Cadmium Chloride results in increased expression of ANGPT1 mRNA CTD PMID:12160620 capsaicin increases expression ISO RGD:733136 6480464 Capsaicin results in increased expression of ANGPT1 mRNA CTD PMID:21310942 carbon nanotube decreases expression EXP 6480464 Nanotubes, Carbon analog results in decreased expression of ANGPT1 mRNA, Nanotubes, Carbon results in decreased expression of ANGPT1 mRNA CTD PMID:25554681 chloroprene increases expression ISO RGD:628896 6480464 Chloroprene results in increased expression of ANGPT1 mRNA CTD PMID:23125180 cisplatin multiple interactions ISO RGD:733136 6480464 [Cisplatin co-treated with Paclitaxel] results in increased expression of ANGPT1 mRNA CTD PMID:20705681 cyclophosphamide increases expression ISO RGD:733136 6480464 Cyclophosphamide results in increased expression of ANGPT1 mRNA CTD PMID:17403535 cyclosporin A decreases expression ISO RGD:733136 6480464 Cyclosporine results in decreased expression of ANGPT1 mRNA CTD PMID:20106945 cylindrospermopsin increases expression ISO RGD:733136 6480464 cylindrospermopsin results in increased expression of ANGPT1 mRNA CTD PMID:24921660 daunorubicin decreases expression ISO RGD:628896 6480464 Daunorubicin results in decreased expression of ANGPT1 mRNA, Daunorubicin results in decreased expression of ANGPT1 protein CTD PMID:16626513 dexamethasone multiple interactions ISO RGD:733136 6480464 [Dexamethasone co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with 1-Methyl-3-isobutylxanthine] results in increased expression of ANGPT1 mRNA, [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin] results in increased expression of ANGPT1 mRNA CTD PMID:16997883 , PMID:28628672 diarsenic trioxide decreases expression ISO RGD:733136 6480464 Arsenic Trioxide results in decreased expression of ANGPT1 mRNA CTD PMID:20458559 dioxygen increases expression EXP 6480464 Oxygen deficiency results in increased expression of ANGPT1 mRNA CTD PMID:20412331 dioxygen multiple interactions EXP 6480464 [NFE2L2 protein affects the susceptibility to Oxygen] which affects the expression of ANGPT1 mRNA, ARNT gene mutant form inhibits the reaction [Oxygen deficiency results in increased expression of ANGPT1 mRNA] CTD PMID:20412331 , PMID:30529165 dorsomorphin multiple interactions ISO RGD:733136 6480464 [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 doxorubicin multiple interactions ISO RGD:733136 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [ANGPT1 protein inhibits the reaction [Doxorubicin results in increased expression of TP53 protein]] more ... CTD PMID:15763944 doxorubicin decreases expression ISO RGD:733136 6480464 Doxorubicin results in decreased expression of ANGPT1 mRNA CTD PMID:29803840 doxorubicin decreases expression EXP 6480464 Doxorubicin results in decreased expression of ANGPT1 mRNA CTD PMID:25896364 doxorubicin decreases response to substance ISO RGD:733136 6480464 ANGPT1 protein results in decreased susceptibility to Doxorubicin CTD PMID:15763944 elemental selenium decreases expression ISO RGD:733136 6480464 Selenium results in decreased expression of ANGPT1 mRNA CTD PMID:19244175 endosulfan decreases expression ISO RGD:628896 6480464 Endosulfan results in decreased expression of ANGPT1 mRNA CTD PMID:29391264 furan increases expression ISO RGD:628896 6480464 furan results in increased expression of ANGPT1 mRNA CTD PMID:27387713 geldanamycin increases expression ISO RGD:733136 6480464 geldanamycin results in increased expression of ANGPT1 mRNA CTD PMID:26705709 genistein decreases expression ISO RGD:733136 6480464 Genistein results in decreased expression of ANGPT1 mRNA CTD PMID:16705744 genistein increases expression EXP 6480464 Genistein results in increased expression of ANGPT1 mRNA CTD PMID:21048042 glyphosate decreases methylation ISO RGD:628896 6480464 glyphosate results in decreased methylation of ANGPT1 gene CTD PMID:31011160 hydrogen peroxide affects expression ISO RGD:733136 6480464 Hydrogen Peroxide affects the expression of ANGPT1 mRNA CTD PMID:20044591 iloprost multiple interactions ISO RGD:733136 6480464 RTKI cpd inhibits the reaction [Iloprost results in increased expression of ANGPT1 mRNA] CTD PMID:16373414 iloprost increases expression ISO RGD:733136 6480464 Iloprost results in increased expression of ANGPT1 mRNA CTD PMID:16373414 indometacin multiple interactions ISO RGD:733136 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin] results in increased expression of ANGPT1 mRNA CTD PMID:28628672 Lasiocarpine decreases expression ISO RGD:733136 6480464 lasiocarpine metabolite results in decreased expression of ANGPT1 mRNA CTD PMID:30465738 LY294002 multiple interactions ISO RGD:733136 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [ANGPT1 protein inhibits the reaction [Doxorubicin results in increased expression of TP53 protein]], 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [ANGPT1 protein results in decreased susceptibility to Doxorubicin] CTD PMID:15763944 mercury dichloride decreases expression ISO RGD:628896 6480464 Mercuric Chloride results in decreased expression of ANGPT1 mRNA CTD PMID:16507785 metformin decreases expression ISO RGD:628896 6480464 Metformin results in decreased expression of ANGPT1 mRNA CTD PMID:31324951 methotrexate decreases expression ISO RGD:733136 6480464 Methotrexate results in decreased expression of ANGPT1 protein CTD PMID:21819747 methoxychlor increases expression ISO RGD:628896 6480464 Methoxychlor results in increased expression of ANGPT1 protein CTD PMID:15503810 methylmercury chloride increases expression ISO RGD:733136 6480464 methylmercuric chloride results in increased expression of ANGPT1 mRNA CTD PMID:28001369 methylmercury chloride decreases expression ISO RGD:733136 6480464 methylmercuric chloride results in decreased expression of ANGPT1 mRNA CTD PMID:28001369 N-acetyl-L-cysteine decreases secretion ISO RGD:733136 6480464 Acetylcysteine results in decreased secretion of ANGPT1 protein CTD PMID:19622383 N-nitrosodiethylamine increases expression ISO RGD:628896 6480464 Diethylnitrosamine results in increased expression of ANGPT1 mRNA CTD PMID:17034775 N-nitrosodiethylamine multiple interactions ISO RGD:628896 6480464 Plant Extracts inhibits the reaction [Diethylnitrosamine results in increased expression of ANGPT1 mRNA] CTD PMID:17034775 naringin affects expression ISO RGD:628896 6480464 naringin affects the expression of ANGPT1 mRNA CTD PMID:24880026 nicotinic acid increases expression ISO RGD:628896 6480464 Niacin results in increased expression of ANGPT1 mRNA CTD PMID:17557352 nicotinic acid increases expression EXP 6480464 Niacin results in increased expression of ANGPT1 mRNA CTD PMID:17557352 ochratoxin A increases expression ISO RGD:628896 6480464 ochratoxin A results in increased expression of ANGPT1 mRNA CTD PMID:23358140 ozone decreases expression EXP 6480464 Ozone results in decreased expression of ANGPT1 mRNA CTD PMID:17460151 ozone increases expression EXP 6480464 Ozone results in increased expression of ANGPT1 mRNA CTD PMID:21543283 paclitaxel multiple interactions ISO RGD:733136 6480464 [Cisplatin co-treated with Paclitaxel] results in increased expression of ANGPT1 mRNA CTD PMID:20705681 panobinostat multiple interactions ISO RGD:733136 6480464 [NOG protein co-treated with Panobinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ANGPT1 mRNA CTD PMID:27188386 panobinostat increases expression ISO RGD:733136 6480464 panobinostat results in increased expression of ANGPT1 mRNA CTD PMID:26272509 paracetamol decreases expression ISO RGD:733136 6480464 Acetaminophen results in decreased expression of ANGPT1 mRNA CTD PMID:29067470 PD123319 multiple interactions ISO RGD:628896 6480464 PD 123319 inhibits the reaction [AGT protein results in increased expression of ANGPT1 mRNA] CTD PMID:14638905 phenylephrine multiple interactions EXP 6480464 ANGPT1 protein inhibits the reaction [Phenylephrine results in increased expression of ACTA1 mRNA] more ... CTD PMID:18502941 phenylephrine increases expression EXP 6480464 Phenylephrine results in increased expression of ANGPT1 mRNA, Phenylephrine results in increased expression of ANGPT1 protein CTD PMID:18502941 phenylmercury acetate increases expression ISO RGD:733136 6480464 Phenylmercuric Acetate results in increased expression of ANGPT1 mRNA CTD PMID:26272509 phenylmercury acetate multiple interactions ISO RGD:733136 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ANGPT1 mRNA CTD PMID:27188386 poly(vinyl chloride) decreases expression ISO RGD:733136 6480464 Polyvinyl Chloride results in decreased expression of ANGPT1 mRNA CTD PMID:12809767 progesterone multiple interactions ISO RGD:733136 6480464 [Estradiol co-treated with Progesterone] results in increased expression of ANGPT1 mRNA CTD PMID:20660070 propanal increases expression ISO RGD:733136 6480464 propionaldehyde results in increased expression of ANGPT1 mRNA CTD PMID:26079696 quercetin multiple interactions ISO RGD:628896 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Quercetin results in increased expression of ANGPT1 mRNA], 4-(4-fluorophenyl)-2-(4-hydroxyphenyl)-5-(4-pyridyl)imidazole inhibits the reaction [Quercetin results in increased expression of ANGPT1 mRNA] CTD PMID:26053266 quercetin increases expression ISO RGD:628896 6480464 Quercetin results in increased expression of ANGPT1 mRNA CTD PMID:26053266 rofecoxib decreases expression ISO RGD:733136 6480464 rofecoxib results in decreased expression of ANGPT1 mRNA CTD PMID:17070997 rotenone decreases expression ISO RGD:628896 6480464 Rotenone results in decreased expression of ANGPT1 mRNA CTD PMID:28374803 roxarsone decreases expression ISO RGD:733136 6480464 Roxarsone results in decreased expression of ANGPT1 mRNA CTD PMID:18414637 SB 431542 multiple interactions ISO RGD:733136 6480464 [NOG protein co-treated with belinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 selenium atom decreases expression ISO RGD:733136 6480464 Selenium results in decreased expression of ANGPT1 mRNA CTD PMID:19244175 sildenafil citrate increases expression ISO RGD:628896 6480464 Sildenafil Citrate results in increased expression of ANGPT1 mRNA, Sildenafil Citrate results in increased expression of ANGPT1 protein CTD PMID:18373738 silicon dioxide decreases expression ISO RGD:733136 6480464 Silicon Dioxide analog results in decreased expression of ANGPT1 mRNA CTD PMID:25895662 silver atom decreases expression EXP 6480464 Silver results in decreased expression of ANGPT1 mRNA CTD PMID:27131904 silver(0) decreases expression EXP 6480464 Silver results in decreased expression of ANGPT1 mRNA CTD PMID:27131904 simvastatin increases expression ISO RGD:628896 6480464 Simvastatin results in increased expression of ANGPT1 more ... CTD PMID:18544044 sodium arsenite decreases secretion ISO RGD:733136 6480464 sodium arsenite results in decreased secretion of ANGPT1 protein CTD PMID:19622383 sodium arsenite increases expression ISO RGD:733136 6480464 sodium arsenite results in increased expression of ANGPT1 mRNA, sodium arsenite results in increased expression of ANGPT1 protein CTD PMID:19622383 , PMID:25493608 streptozocin increases expression ISO RGD:628896 6480464 Streptozocin results in increased expression of ANGPT1 mRNA, Streptozocin results in increased expression of ANGPT1 protein CTD PMID:15643138 streptozocin decreases expression ISO RGD:628896 6480464 Streptozocin results in decreased expression of ANGPT1 mRNA CTD PMID:19958114 testosterone multiple interactions ISO RGD:628896 6480464 [bisphenol A co-treated with Testosterone] results in decreased expression of ANGPT1 mRNA CTD PMID:26496021 testosterone enanthate affects expression ISO RGD:733136 6480464 testosterone enanthate affects the expression of ANGPT1 mRNA CTD PMID:17440010 tetrachloromethane decreases expression EXP 6480464 Carbon Tetrachloride results in decreased expression of ANGPT1 mRNA CTD PMID:17484886 tetrachloromethane increases expression ISO RGD:628896 6480464 Carbon Tetrachloride results in increased expression of ANGPT1 mRNA, Carbon Tetrachloride results in increased expression of ANGPT1 protein CTD PMID:15135347 thimerosal decreases expression ISO RGD:733136 6480464 Thimerosal results in decreased expression of ANGPT1 mRNA CTD PMID:27188386 torcetrapib increases expression ISO RGD:733136 6480464 torcetrapib results in increased expression of ANGPT1 mRNA CTD PMID:23228038 trichostatin A increases expression ISO RGD:733136 6480464 trichostatin A results in increased expression of ANGPT1 mRNA CTD PMID:24935251 , PMID:26272509 trichostatin A multiple interactions ISO RGD:733136 6480464 [NOG protein co-treated with trichostatin A co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ANGPT1 mRNA CTD PMID:27188386 tyrphostin AG 1478 multiple interactions ISO RGD:733136 6480464 RTKI cpd inhibits the reaction [Iloprost results in increased expression of ANGPT1 mRNA] CTD PMID:16373414 valproic acid affects expression ISO RGD:733136 6480464 Valproic Acid affects the expression of ANGPT1 mRNA CTD PMID:25979313 valproic acid decreases expression ISO RGD:733136 6480464 Valproic Acid results in decreased expression of ANGPT1 mRNA CTD PMID:28001369 valproic acid multiple interactions ISO RGD:733136 6480464 [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ANGPT1 mRNA CTD PMID:27188386 valproic acid increases expression ISO RGD:733136 6480464 Valproic Acid results in increased expression of ANGPT1 mRNA CTD PMID:23179753 more ... valsartan multiple interactions ISO RGD:628896 6480464 Valsartan inhibits the reaction [AGT protein results in increased expression of ANGPT1 mRNA], Valsartan inhibits the reaction [AGT protein results in increased expression of ANGPT1 protein] CTD PMID:14638905 vancomycin increases expression EXP 6480464 Vancomycin results in increased expression of ANGPT1 mRNA CTD PMID:18930951 vinclozolin affects expression ISO RGD:628896 6480464 vinclozolin affects the expression of ANGPT1 mRNA CTD PMID:19015723 vinclozolin increases expression ISO RGD:628896 6480464 vinclozolin results in increased expression of ANGPT1 mRNA CTD PMID:23034163 vitamin E decreases expression ISO RGD:733136 6480464 Vitamin E results in decreased expression of ANGPT1 mRNA CTD PMID:19244175 vorinostat multiple interactions ISO RGD:733136 6480464 [NOG protein co-treated with Vorinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of ANGPT1 mRNA CTD PMID:27188386 vorinostat increases expression ISO RGD:733136 6480464 vorinostat results in increased expression of ANGPT1 mRNA CTD PMID:26272509 zinc atom decreases expression EXP 6480464 Zinc deficiency results in decreased expression of ANGPT1 mRNA CTD PMID:20857495 zinc(0) decreases expression EXP 6480464 Zinc deficiency results in decreased expression of ANGPT1 mRNA CTD PMID:20857495
Biological Process activation of transmembrane receptor protein tyrosine kinase activity ISO UniProtKB:Q15389 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 angiogenesis IMP 2290270 (MGI:MGI:3805145, PMID:18505784) MGI MGI:MGI:3805145 , PMID:18505784 angiogenesis IDA 2290270 (MGI:MGI:1351100, PMID:10617467) MGI MGI:MGI:1351100 , PMID:10617467 branching involved in blood vessel morphogenesis TAS 2290270 (MGI:MGI:4943617, PMID:20299672) DFLAT MGI:MGI:4943617 , PMID:20299672 cardiac muscle tissue morphogenesis TAS 2290270 (MGI:MGI:4943617, PMID:20299672) DFLAT MGI:MGI:4943617 , PMID:20299672 cell differentiation IEA UniProtKB-KW:KW-0221 2290270 UniProtKB GO_REF:0000004, MGI:MGI:1354194 cell-substrate adhesion IDA 2290270 (MGI:MGI:1315113, PMID:9846489) MGI MGI:MGI:1315113 , PMID:9846489 endocardium morphogenesis TAS 2290270 (MGI:MGI:4943617, PMID:20299672) DFLAT MGI:MGI:4943617 , PMID:20299672 endoderm development TAS 2290270 (MGI:MGI:1332308, PMID:10051567) MGI MGI:MGI:1332308 , PMID:10051567 glomerulus vasculature development IDA 2290270 (MGI:MGI:2150220, PMID:11507774) MGI MGI:MGI:2150220 , PMID:11507774 glomerulus vasculature development ISO RGD:628896 2290270 RGD GO_REF:0000096, MGI:MGI:4417868 hemopoiesis IDA 2290270 (MGI:MGI:3051189, PMID:15260986) MGI MGI:MGI:3051189 , PMID:15260986 heparin biosynthetic process ISO UniProtKB:Q15389 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 in utero embryonic development IMP MGI:MGI:2180145 2290270 (MGI:MGI:1930385, PMID:11172728) MGI MGI:MGI:1930385 , PMID:11172728 in utero embryonic development IGI MGI:MGI:99906 2290270 (MGI:MGI:1930385, PMID:11172728) MGI MGI:MGI:1930385 , PMID:11172728 multicellular organism development IEA UniProtKB-KW:KW-0217 2290270 UniProtKB GO_REF:0000004, MGI:MGI:1354194 negative regulation of apoptotic process ISO RGD:628896 2290270 RGD GO_REF:0000096, MGI:MGI:4417868 negative regulation of apoptotic process ISO UniProtKB:Q15389 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 negative regulation of cell adhesion ISO UniProtKB:Q15389 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 negative regulation of cytokine secretion involved in immune response IDA 2290270 (MGI:MGI:4437182, PMID:20060382) MGI MGI:MGI:4437182 , PMID:20060382 negative regulation of endothelial cell apoptotic process ISO UniProtKB:Q15389 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 negative regulation of neuron apoptotic process IDA 2290270 (MGI:MGI:3848848, PMID:19409199) MGI MGI:MGI:3848848 , PMID:19409199 negative regulation of neuron apoptotic process IGI MGI:MGI:98664 2290270 (MGI:MGI:3848848, PMID:19409199) MGI MGI:MGI:3848848 , PMID:19409199 negative regulation of protein import into nucleus IDA 2290270 (MGI:MGI:4437182, PMID:20060382) MGI MGI:MGI:4437182 , PMID:20060382 negative regulation of protein phosphorylation IDA 2290270 (MGI:MGI:4437182, PMID:20060382) MGI MGI:MGI:4437182 , PMID:20060382 negative regulation of vascular permeability ISO UniProtKB:Q15389 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 negative regulation of vascular permeability IDA 2290270 (MGI:MGI:1351100 more ... MGI MGI:MGI:1351100 more ... ovarian follicle development ISO RGD:628896 2290270 RGD GO_REF:0000096, MGI:MGI:4417868 positive chemotaxis ISO UniProtKB:Q15389 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 positive regulation of blood vessel endothelial cell migration ISO UniProtKB:Q15389 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 positive regulation of cell adhesion IDA 2290270 (MGI:MGI:3051189, PMID:15260986) MGI MGI:MGI:3051189 , PMID:15260986 positive regulation of endothelial cell migration TAS 2290270 (MGI:MGI:4943617, PMID:20299672) DFLAT MGI:MGI:4943617 , PMID:20299672 positive regulation of endothelial cell migration ISO UniProtKB:Q15389 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 positive regulation of ERK1 and ERK2 cascade ISO UniProtKB:Q15389 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 positive regulation of peptidyl-serine phosphorylation IDA 2290270 (MGI:MGI:3848848, PMID:19409199) MGI MGI:MGI:3848848 , PMID:19409199 positive regulation of peptidyl-tyrosine phosphorylation ISO UniProtKB:Q15389 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 positive regulation of peptidyl-tyrosine phosphorylation IDA 2290270 (MGI:MGI:3848848 more ... MGI MGI:MGI:3848848 more ... positive regulation of phosphatidylinositol 3-kinase signaling IDA 2290270 (MGI:MGI:3848848, PMID:19409199) MGI MGI:MGI:3848848 , PMID:19409199 positive regulation of protein kinase B signaling ISO UniProtKB:Q15389 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 positive regulation of protein ubiquitination ISO UniProtKB:Q15389 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 positive regulation of receptor internalization ISO UniProtKB:Q15389 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 positive regulation of vascular endothelial growth factor receptor signaling pathway TAS 2290270 (MGI:MGI:4830635, PMID:20406889) DFLAT MGI:MGI:4830635 , PMID:20406889 protein homooligomerization ISO RGD:628896 2290270 RGD GO_REF:0000096, MGI:MGI:4417868 protein localization to cell surface ISO UniProtKB:Q15389 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 regulation of I-kappaB kinase/NF-kappaB signaling IGI MGI:MGI:98664 2290270 (MGI:MGI:4437182, PMID:20060382) MGI MGI:MGI:4437182 , PMID:20060382 regulation of macrophage migration inhibitory factor signaling pathway IDA 2290270 (MGI:MGI:4437182, PMID:20060382) MGI MGI:MGI:4437182 , PMID:20060382 regulation of protein binding IDA 2290270 (MGI:MGI:4437182, PMID:20060382) MGI MGI:MGI:4437182 , PMID:20060382 regulation of skeletal muscle satellite cell proliferation ISO UniProtKB:Q15389 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 regulation of tumor necrosis factor production IDA 2290270 (MGI:MGI:4437182, PMID:20060382) MGI MGI:MGI:4437182 , PMID:20060382 sprouting angiogenesis ISO UniProtKB:Q15389 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 Tie signaling pathway TAS 2290270 (MGI:MGI:4943617, PMID:20299672) DFLAT MGI:MGI:4943617 , PMID:20299672 Tie signaling pathway ISO UniProtKB:Q15389 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 transmembrane receptor protein tyrosine kinase signaling pathway IDA 2290270 (MGI:MGI:84852, PMID:8980224) MGI MGI:MGI:84852 , PMID:8980224 vasculogenesis TAS 2290270 (MGI:MGI:4943617, PMID:20299672) DFLAT MGI:MGI:4943617 , PMID:20299672 vasculogenesis involved in coronary vascular morphogenesis TAS 2290270 (MGI:MGI:4943617, PMID:20299672) DFLAT MGI:MGI:4943617 , PMID:20299672 Cellular Component extracellular region IEA UniProtKB-KW:KW-0964 2290270 UniProtKB GO_REF:0000004, MGI:MGI:1354194 extracellular space ISO UniProtKB:Q15389 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 extracellular space ISO RGD:628896 2290270 RGD GO_REF:0000096, MGI:MGI:4417868 membrane raft ISO UniProtKB:Q15389 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 microvillus ISO UniProtKB:Q15389 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 plasma membrane ISO UniProtKB:Q15389 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 Molecular Function receptor tyrosine kinase binding ISO UniProtKB:Q15389 2290270 MGI GO_REF:0000096, MGI:MGI:4834177 signaling receptor binding IPI UniProtKB:Q02858 2290270 (MGI:MGI:84853, PMID:8980223) MGI MGI:MGI:84853 , PMID:8980223 vascular endothelial growth factor receptor binding TAS 2290270 (MGI:MGI:1332308, PMID:10051567) MGI MGI:MGI:1332308 , PMID:10051567
Gene-Chemical Interaction Annotations
