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Gene: Tnfsf4 (tumor necrosis factor (ligand) superfamily, member 4) Mus musculus
Symbol: Tnfsf4
Name: tumor necrosis factor (ligand) superfamily, member 4
Description: Exhibits tumor necrosis factor receptor binding activity. Involved in several processes, including positive regulation of cytokine production; regulation of lymphocyte activation; and regulation of protein secretion. Predicted to localize to cell surface and extracellular space. Used to study primary pulmonary hypertension and type 1 diabetes mellitus. Human ortholog(s) of this gene implicated in myocardial infarction. Is expressed in sensory organ and skeleton. Orthologous to human TNFSF4 (TNF superfamily member 4); INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; calcipotriol; carbon monoxide.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: Ath-1; Ath1; atherosclerosis 1; CD134L; gp34; OX-40L; OX40 ligand; Ox40l; tax-transcriptionally activated glycoprotein 1 ligand; Tnlg2b; tumor necrosis factor ligand 2b; tumor necrosis factor ligand superfamily member 4; TXGP1; Txgp1l
Homo sapiens (human) : TNFSF4 (TNF superfamily member 4)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Tnfsf4 (TNF superfamily member 4)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tnfsf4 (TNF superfamily member 4)
Pan paniscus (bonobo/pygmy chimpanzee) : TNFSF4 (TNF superfamily member 4)
Canis lupus familiaris (dog) : TNFSF4 (TNF superfamily member 4)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tnfsf4 (TNF superfamily member 4)
Sus scrofa (pig) : TNFSF4 (TNF superfamily member 4)
Chlorocebus sabaeus (African green monkey) : TNFSF4 (TNF superfamily member 4)
Heterocephalus glaber (naked mole-rat) : Tnfsf4 (TNF superfamily member 4)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38 Ensembl1161,395,409 - 161,418,410 (+)EnsemblGRCm38mm10GRCm38
GRCm381161,395,438 - 161,418,206 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371163,325,569 - 163,348,337 (+)NCBIGRCm37mm9NCBIm37
MGSCv361163,232,135 - 163,254,883 (+)NCBImm8
Celera1163,843,815 - 163,866,564 (+)NCBICelera
Cytogenetic Map1H2.1NCBI
cM Map169.75NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Tnfsf4
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 733125
Created: 2004-01-12
Species: Mus musculus
Last Modified: 2020-03-25
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.