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Gene: Flg (filaggrin) Mus musculus
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Symbol: Flg
Name: filaggrin
Description: Exhibits keratin filament binding activity. Involved in epidermis development; establishment of skin barrier; and intermediate filament organization. Localizes to cornified envelope and keratohyalin granule. Is expressed in eyelid epithelium; foregut; and skin. Used to study atopic dermatitis 2; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; benzalkonium chloride.
Type: protein-coding
RefSeq Status: MODEL
Also known as: AW107830; fillagrin; ft; keratin intermediate filament-associated protein; LOW QUALITY PROTEIN: filaggrin; profilaggrin
Orthologs:
Homo sapiens (human) : FLG (filaggrin)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Flg (filaggrin)  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : FLG (filaggrin)
Canis lupus familiaris (dog) : FLG (filaggrin)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 Ensembl393,273,523 - 93,293,686 (+)EnsemblGRCm38mm10GRCm38
GRCm38393,273,546 - 93,293,689 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv37393,089,108 - 93,097,615 (+)NCBIGRCm37mm9NCBIm37
MGSCv36393,367,872 - 93,379,097 (+)NCBImm8
Celera393,804,333 - 93,822,603 (-)NCBICelera
Cytogenetic Map3F2.1NCBI
cM Map340.16NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
 
More on Flg
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 10592
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-07-14
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.