(-)-selegiline multiple interactions ISO RGD:730938 6480464 Selegiline inhibits the reaction [linsidomine results in increased expression of PRKN protein] CTD PMID:12880480 (S)-nicotine decreases expression ISO RGD:730938 6480464 Nicotine results in decreased expression of PRKN mRNA CTD PMID:16949557 1,2-dimethylhydrazine decreases expression EXP 6480464 1, 2-Dimethylhydrazine results in decreased expression of PARK2 mRNA CTD PMID:22206623 1,4-benzoquinone increases expression ISO RGD:730938 6480464 quinone results in increased expression of PRKN mRNA, quinone results in increased expression of PRKN protein CTD PMID:29567065 1,4-benzoquinone multiple interactions ISO RGD:730938 6480464 Acetylcysteine inhibits the reaction [quinone results in increased expression of PRKN protein] more ... CTD PMID:29567065 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine multiple interactions ISO RGD:730938 6480464 PRKN protein inhibits the reaction [1-Methyl-4-phenyl-1 more ... CTD PMID:25447324 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine multiple interactions EXP 6480464 AM 1241 inhibits the reaction [1-Methyl-4-phenyl-1 more ... CTD PMID:22511790 , PMID:28978077 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine decreases response to substance EXP 6480464 PRKN protein results in decreased susceptibility to 1-Methyl-4-phenyl-1 more ... CTD PMID:23643664 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine decreases expression EXP 6480464 1-Methyl-4-phenyl-1 more ... CTD PMID:23643664 , PMID:28978077 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine increases expression EXP 6480464 1-Methyl-4-phenyl-1 more ... CTD PMID:22342763 , PMID:27566062 2,3,7,8-tetrachlorodibenzodioxine affects expression EXP 6480464 Tetrachlorodibenzodioxin affects the expression of PRKN mRNA CTD PMID:21570461 3-BROMO-7-NITROINDAZOLE multiple interactions EXP 6480464 3-bromo-7-nitroindazole inhibits the reaction [[Paraquat co-treated with Maneb] results in increased nitrosation of PRKN protein] CTD PMID:23985028 4,4'-sulfonyldiphenol decreases expression EXP 6480464 bis(4-hydroxyphenyl)sulfone results in decreased expression of PARK2 mRNA CTD PMID:30951980 4,4'-sulfonyldiphenol decreases methylation ISO RGD:730938 6480464 bis(4-hydroxyphenyl)sulfone results in decreased methylation of PRKN gene CTD PMID:31601247 4-hydroxy-TEMPO multiple interactions ISO RGD:61797 6480464 tempol inhibits the reaction [Ketoconazole results in increased expression of PRKN mRNA], tempol inhibits the reaction [Ketoconazole results in increased expression of PRKN protein] CTD PMID:25787151 6-propyl-2-thiouracil increases expression ISO RGD:61797 6480464 Propylthiouracil results in increased expression of PRKN mRNA CTD PMID:24780913 acetaldehyde multiple interactions ISO RGD:730938 6480464 PRKN protein inhibits the reaction [Acetaldehyde results in decreased expression of FTH1 protein] more ... CTD PMID:35595033 acetaldehyde decreases expression ISO RGD:730938 6480464 Acetaldehyde results in decreased expression of PRKN mRNA, Acetaldehyde results in decreased expression of PRKN protein CTD PMID:35595033 acetamide decreases expression ISO RGD:61797 6480464 acetamide results in decreased expression of PRKN mRNA CTD PMID:31881176 acetylcholine multiple interactions EXP 6480464 Acetylcholine inhibits the reaction [[Aluminum Chloride results in increased abundance of Aluminum] which results in increased expression of PRKN protein] CTD PMID:34547296 aflatoxin B1 decreases expression ISO RGD:730938 6480464 Aflatoxin B1 results in decreased expression of PARK2 mRNA, Aflatoxin B1 results in decreased expression of PRKN mRNA CTD PMID:31555880 more ... aflatoxin B1 multiple interactions EXP 6480464 PRKN protein affects the reaction [Aflatoxin B1 results in decreased expression of BCL2 protein] more ... CTD PMID:35304092 aflatoxin B1 increases expression EXP 6480464 Aflatoxin B1 results in increased expression of PRKN mRNA, Aflatoxin B1 results in increased expression of PRKN protein CTD PMID:35304092 aflatoxin B1 affects methylation ISO RGD:730938 6480464 Aflatoxin B1 affects the methylation of PRKN intron CTD PMID:30157460 aflatoxin B1 decreases methylation ISO RGD:730938 6480464 Aflatoxin B1 results in decreased methylation of PRKN gene CTD PMID:27153756 Aflatoxin B2 alpha affects methylation ISO RGD:730938 6480464 aflatoxin B2 affects the methylation of PRKN intron CTD PMID:30157460 aldehydo-D-glucose decreases expression ISO RGD:61797 6480464 Glucose results in decreased expression of PRKN protein CTD PMID:35243728 aldehydo-D-glucose multiple interactions ISO RGD:61797 6480464 Inositol inhibits the reaction [Glucose results in decreased expression of PRKN protein] CTD PMID:35243728 all-trans-retinoic acid multiple interactions ISO RGD:730938 6480464 Tretinoin affects the reaction [1-Methyl-4-phenylpyridinium affects the expression of PRKN protein alternative form] more ... CTD PMID:28688199 aluminium atom multiple interactions EXP 6480464 [Aluminum Chloride results in increased abundance of Aluminum] which results in increased expression of PRKN mRNA more ... CTD PMID:34547296 aluminium(0) multiple interactions EXP 6480464 [Aluminum Chloride results in increased abundance of Aluminum] which results in increased expression of PRKN mRNA more ... CTD PMID:34547296 ammonium chloride affects expression ISO RGD:61797 6480464 Ammonium Chloride affects the expression of PRKN mRNA CTD PMID:16483693 amphetamine increases response to substance EXP 6480464 PRKN protein results in increased susceptibility to Amphetamine CTD PMID:12915482 amphetamine multiple interactions EXP 6480464 PRKN protein promotes the reaction [Amphetamine results in increased abundance of Dopamine] CTD PMID:12915482 androgen antagonist multiple interactions ISO RGD:61797 6480464 [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in decreased expression of PRKN mRNA CTD PMID:25607892 antimycin A multiple interactions ISO RGD:730938 6480464 [oligomycin A co-treated with Antimycin A] affects the localization of PRKN protein more ... CTD PMID:28366621 , PMID:28673964 antimycin A decreases expression ISO RGD:730938 6480464 Antimycin A results in decreased expression of PRKN mRNA CTD PMID:33512557 antirheumatic drug increases expression ISO RGD:730938 6480464 Antirheumatic Agents results in increased expression of PRKN mRNA CTD PMID:24449571 aristolochic acid A decreases expression ISO RGD:730938 6480464 aristolochic acid I results in decreased expression of PRKN mRNA CTD PMID:33212167 Aroclor 1254 increases expression ISO RGD:61797 6480464 Chlorodiphenyl (54% Chlorine) results in increased expression of PRKN protein CTD PMID:16174552 arsane affects methylation ISO RGD:730938 6480464 Arsenic affects the methylation of PRKN gene CTD PMID:25304211 arsenic atom affects methylation ISO RGD:730938 6480464 Arsenic affects the methylation of PRKN gene CTD PMID:25304211 arsenous acid affects localization EXP 6480464 Arsenic Trioxide affects the localization of PRKN protein CTD PMID:24801902 arsenous acid decreases expression ISO RGD:61797 6480464 Arsenic Trioxide results in decreased expression of PRKN protein CTD PMID:30551535 arsenous acid multiple interactions ISO RGD:61797 6480464 Taurine inhibits the reaction [Arsenic Trioxide results in decreased expression of PRKN protein] CTD PMID:30551535 atrazine increases expression ISO RGD:61797 6480464 Atrazine results in increased expression of PRKN mRNA, Atrazine results in increased expression of PRKN protein CTD PMID:30084861 azoxystrobin decreases expression ISO RGD:730938 6480464 azoxystrobin results in decreased expression of PRKN mRNA CTD PMID:33512557 benzo[a]pyrene increases expression ISO RGD:61797 6480464 Benzo(a)pyrene results in increased expression of PRKN protein CTD PMID:32619457 benzo[a]pyrene affects methylation ISO RGD:730938 6480464 Benzo(a)pyrene affects the methylation of PRKN intron CTD PMID:30157460 benzo[a]pyrene decreases expression EXP 6480464 Benzo(a)pyrene results in decreased expression of PRKN mRNA CTD PMID:21569818 benzo[a]pyrene decreases expression ISO RGD:730938 6480464 Benzo(a)pyrene results in decreased expression of PARK2 mRNA, Benzo(a)pyrene results in decreased expression of PRKN mRNA CTD PMID:31555880 more ... benzo[a]pyrene multiple interactions ISO RGD:61797 6480464 [Resveratrol co-treated with Benzo(a)pyrene] results in increased expression of PRKN protein CTD PMID:32619457 benzo[e]pyrene increases methylation ISO RGD:730938 6480464 benzo(e)pyrene results in increased methylation of PRKN intron CTD PMID:30157460 bis(2-ethylhexyl) phthalate multiple interactions ISO RGD:61797 6480464 [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of PRKN mRNA CTD PMID:25607892 bis(2-ethylhexyl) phthalate increases expression ISO RGD:730938 6480464 Diethylhexyl Phthalate results in increased expression of PRKN mRNA CTD PMID:34822940 bisphenol A multiple interactions ISO RGD:61797 6480464 [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in decreased expression of PRKN mRNA, [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in decreased expression of PRKN mRNA CTD PMID:25607892 bisphenol A multiple interactions ISO RGD:730938 6480464 [bisphenol A co-treated with Fulvestrant] results in increased methylation of PRKN gene CTD PMID:31601247 bisphenol A increases methylation ISO RGD:61797 6480464 bisphenol A results in increased methylation of PRKN gene CTD PMID:28505145 bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of PARK2 mRNA CTD PMID:30951980 bisphenol A decreases expression ISO RGD:61797 6480464 bisphenol A results in decreased expression of PRKN mRNA CTD PMID:25181051 bupivacaine multiple interactions EXP 6480464 HSPA12A protein inhibits the reaction [Bupivacaine results in decreased expression of PRKN protein] CTD PMID:34793778 bupivacaine decreases expression EXP 6480464 Bupivacaine results in decreased expression of PRKN protein CTD PMID:34793778 Butylparaben multiple interactions ISO RGD:61797 6480464 [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in decreased expression of PRKN mRNA, [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in decreased expression of PRKN mRNA CTD PMID:25607892 C60 fullerene decreases expression ISO RGD:61797 6480464 fullerene C60 results in decreased expression of PRKN mRNA CTD PMID:19167457 cadmium atom multiple interactions EXP 6480464 3-(2 more ... CTD PMID:25464205 , PMID:34952138 cadmium atom multiple interactions ISO RGD:730938 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of PRKN protein CTD PMID:32142837 cadmium atom increases expression EXP 6480464 Cadmium results in increased expression of PRKN CTD PMID:25464205 cadmium dichloride multiple interactions EXP 6480464 3-(2 more ... CTD PMID:34952138 cadmium dichloride multiple interactions ISO RGD:730938 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of PRKN protein CTD PMID:32142837 carbon nanotube decreases expression EXP 6480464 Nanotubes more ... CTD PMID:25554681 , PMID:25620056 carbonyl cyanide p-trifluoromethoxyphenylhydrazone multiple interactions EXP 6480464 PINK1 protein affects the reaction [Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone affects the localization of PRKN protein] CTD PMID:24879156 carbonyl cyanide p-trifluoromethoxyphenylhydrazone affects localization EXP 6480464 Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone affects the localization of PRKN protein CTD PMID:24879156 carnosic acid multiple interactions ISO RGD:730938 6480464 PINK1 protein affects the reaction [salvin inhibits the reaction [Oxidopamine results in decreased expression of PRKN protein]] more ... CTD PMID:30707903 , PMID:31705926 carnosic acid increases expression ISO RGD:730938 6480464 salvin results in increased expression of PRKN protein CTD PMID:31705926 CCCP affects localization ISO RGD:61797 6480464 Carbonyl Cyanide m-Chlorophenyl Hydrazone affects the localization of PRKN protein CTD PMID:24879156 CCCP decreases response to substance EXP 6480464 PRKN protein results in decreased susceptibility to Carbonyl Cyanide m-Chlorophenyl Hydrazone CTD PMID:16517603 CCCP increases response to substance EXP 6480464 PRKN gene mutant form results in increased susceptibility to Carbonyl Cyanide m-Chlorophenyl Hydrazone CTD PMID:16517603 CCCP decreases expression ISO RGD:730938 6480464 Carbonyl Cyanide m-Chlorophenyl Hydrazone results in decreased expression of PRKN protein CTD PMID:28688199 CCCP affects expression ISO RGD:730938 6480464 Carbonyl Cyanide m-Chlorophenyl Hydrazone affects the expression of PRKN protein alternative form CTD PMID:28688199 CCCP increases phosphorylation EXP 6480464 Carbonyl Cyanide m-Chlorophenyl Hydrazone results in increased phosphorylation of PRKN protein CTD PMID:29660402 CCCP multiple interactions EXP 6480464 1 more ... CTD PMID:22872702 , PMID:24879156 CCCP affects localization EXP 6480464 Carbonyl Cyanide m-Chlorophenyl Hydrazone affects the localization of PRKN protein CTD PMID:22872702 CCCP affects localization ISO RGD:730938 6480464 Carbonyl Cyanide m-Chlorophenyl Hydrazone affects the localization of PRKN protein CTD PMID:22872702 more ... CCCP multiple interactions ISO RGD:730938 6480464 [Carbonyl Cyanide m-Chlorophenyl Hydrazone co-treated with PRKN protein] results in increased expression of PINK1 protein more ... CTD PMID:24879156 more ... CCCP increases phosphorylation ISO RGD:61797 6480464 Carbonyl Cyanide m-Chlorophenyl Hydrazone results in increased phosphorylation of PRKN protein CTD PMID:24879156 CCCP multiple interactions ISO RGD:61797 6480464 BECN1 protein affects the reaction [Carbonyl Cyanide m-Chlorophenyl Hydrazone affects the localization of PRKN protein] more ... CTD PMID:24879156 CGP 52608 multiple interactions ISO RGD:730938 6480464 CGP 52608 promotes the reaction [RORA protein binds to PARK2 gene] CTD PMID:28238834 chloroquine multiple interactions EXP 6480464 Chloroquine inhibits the reaction [Acetaminophen results in increased expression of PRKN protein], Chloroquine inhibits the reaction [coenzyme Q10 promotes the reaction [Acetaminophen results in increased expression of PRKN protein]] CTD PMID:33271250 chloroquine multiple interactions ISO RGD:61797 6480464 Chloroquine inhibits the reaction [Venlafaxine Hydrochloride inhibits the reaction [Rotenone results in decreased expression of PRKN protein]] CTD PMID:35104487 chlorpyrifos affects localization ISO RGD:730938 6480464 Chlorpyrifos affects the localization of PRKN protein CTD PMID:26070385 chlorpyrifos decreases expression EXP 6480464 Chlorpyrifos results in decreased expression of PRKN mRNA CTD PMID:29156651 chlorpyrifos multiple interactions ISO RGD:730938 6480464 PRKN protein inhibits the reaction [Chlorpyrifos results in decreased expression of NDUFS3 protein] more ... CTD PMID:26070385 chromium(6+) increases expression EXP 6480464 chromium hexavalent ion results in increased expression of PRKN protein CTD PMID:32866567 chromium(6+) increases expression ISO RGD:730938 6480464 chromium hexavalent ion results in increased expression of PRKN protein CTD PMID:30715550 , PMID:32866567 chromium(6+) multiple interactions ISO RGD:730938 6480464 HMGA2 protein promotes the reaction [chromium hexavalent ion results in increased expression of PRKN protein] CTD PMID:32866567 cinnarizine decreases response to substance EXP 6480464 PRKN results in decreased susceptibility to Cinnarizine CTD PMID:15993444 cisplatin increases expression ISO RGD:61797 6480464 Cisplatin results in increased expression of PRKN protein CTD PMID:28698153 cisplatin multiple interactions ISO RGD:61797 6480464 Curcumin inhibits the reaction [Cisplatin results in increased expression of PRKN protein] CTD PMID:28698153 clothianidin decreases expression ISO RGD:730938 6480464 clothianidin results in decreased expression of PARK2 mRNA CTD PMID:35690182 coenzyme Q10 multiple interactions EXP 6480464 Chloroquine inhibits the reaction [coenzyme Q10 promotes the reaction [Acetaminophen results in increased expression of PRKN protein]], coenzyme Q10 promotes the reaction [Acetaminophen results in increased expression of PRKN protein] CTD PMID:33271250 curcumin multiple interactions ISO RGD:61797 6480464 Curcumin inhibits the reaction [Cisplatin results in increased expression of PRKN protein] CTD PMID:28698153 cyclosporin A multiple interactions EXP 6480464 Cyclosporine inhibits the reaction [Cadmium results in increased expression of PRKN] CTD PMID:25464205 cyclosporin A multiple interactions ISO RGD:730938 6480464 Cyclosporine inhibits the reaction [quinone results in increased expression of PRKN mRNA], Cyclosporine inhibits the reaction [quinone results in increased expression of PRKN protein] CTD PMID:29567065 D-glucose decreases expression ISO RGD:61797 6480464 Glucose results in decreased expression of PRKN protein CTD PMID:35243728 D-glucose multiple interactions ISO RGD:61797 6480464 Inositol inhibits the reaction [Glucose results in decreased expression of PRKN protein] CTD PMID:35243728 DDE multiple interactions ISO RGD:61797 6480464 [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of PRKN mRNA CTD PMID:25607892 diarsenic trioxide affects localization EXP 6480464 Arsenic Trioxide affects the localization of PRKN protein CTD PMID:24801902 diarsenic trioxide decreases expression ISO RGD:61797 6480464 Arsenic Trioxide results in decreased expression of PRKN protein CTD PMID:30551535 diarsenic trioxide multiple interactions ISO RGD:61797 6480464 Taurine inhibits the reaction [Arsenic Trioxide results in decreased expression of PRKN protein] CTD PMID:30551535 diazinon decreases expression ISO RGD:61797 6480464 Diazinon results in decreased expression of PRKN mRNA CTD PMID:21968025 dibutyl phthalate multiple interactions ISO RGD:61797 6480464 [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of PRKN mRNA CTD PMID:25607892 dieldrin increases response to substance ISO RGD:730938 6480464 PARK2 gene mutant form results in increased susceptibility to Dieldrin CTD PMID:32421776 dioxygen multiple interactions EXP 6480464 [Blood Glucose deficiency co-treated with Oxygen deficiency] results in decreased expression of PRKN protein more ... CTD PMID:28477916 dioxygen multiple interactions ISO RGD:61797 6480464 [Oxygen deficiency co-treated with Oxygen] results in decreased expression of PRKN protein more ... CTD PMID:34358556 dopamine multiple interactions ISO RGD:730938 6480464 PRKN protein inhibits the reaction [Dopamine results in increased abundance of Reactive Oxygen Species] more ... CTD PMID:15198987 dopamine multiple interactions EXP 6480464 PRKN mutant form results in increased abundance of and results in increased metabolism of Dopamine more ... CTD PMID:12915482 , PMID:15993444 dopamine increases expression ISO RGD:730938 6480464 Dopamine results in increased expression of PRKN mRNA CTD PMID:16987221 dorsomorphin multiple interactions ISO RGD:61797 6480464 dorsomorphin inhibits the reaction [sappanone A inhibits the reaction [[Oxygen deficiency co-treated with Oxygen] results in decreased expression of PRKN protein]] CTD PMID:34358556 doxorubicin increases expression ISO RGD:61797 6480464 Doxorubicin results in increased expression of PRKN protein CTD PMID:26678157 , PMID:29966675 doxorubicin decreases expression ISO RGD:61797 6480464 Doxorubicin results in decreased expression of PRKN mRNA, Doxorubicin results in decreased expression of PRKN protein CTD PMID:32434049 doxorubicin multiple interactions ISO RGD:61797 6480464 Doxorubicin inhibits the reaction [YAP1 protein binds to PRKN promoter] CTD PMID:32434049 doxorubicin decreases expression EXP 6480464 Doxorubicin results in decreased expression of PRKN protein CTD PMID:32434049 doxorubicin multiple interactions ISO RGD:730938 6480464 3-(2 more ... CTD PMID:29729358 doxorubicin increases expression ISO RGD:730938 6480464 Doxorubicin results in increased expression of PRKN protein CTD PMID:29729358 doxorubicin decreases expression ISO RGD:730938 6480464 Doxorubicin results in decreased expression of PRKN mRNA CTD PMID:29803840 doxorubicin multiple interactions EXP 6480464 PRKN protein affects the reaction [Doxorubicin results in increased expression of MYH7 mRNA], PRKN protein affects the reaction [Doxorubicin results in increased expression of NPPB mRNA] CTD PMID:32434049 doxorubicin decreases response to substance ISO RGD:61797 6480464 PRKN protein results in decreased susceptibility to Doxorubicin CTD PMID:32434049 emtricitabine decreases expression ISO RGD:730938 6480464 Emtricitabine results in decreased expression of PRKN protein CTD PMID:31545371 emtricitabine multiple interactions ISO RGD:730938 6480464 [Emtricitabine co-treated with Tenofovir] results in decreased expression of PRKN protein CTD PMID:31545371 enzacamene multiple interactions ISO RGD:61797 6480464 [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in decreased expression of PRKN mRNA, [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben] results in decreased expression of PRKN mRNA CTD PMID:25607892 epoxiconazole multiple interactions ISO RGD:61797 6480464 [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of PRKN mRNA CTD PMID:25607892 epoxomicin decreases expression ISO RGD:730938 6480464 epoxomicin results in decreased expression of PRKN mRNA CTD PMID:18586549 epoxomicin decreases expression ISO RGD:61797 6480464 epoxomicin results in decreased expression of PRKN mRNA CTD PMID:18586549 epoxomicin multiple interactions ISO RGD:61797 6480464 epoxomicin inhibits the reaction [PRKN protein results in decreased susceptibility to Ceramides] CTD PMID:12588799 ethanol decreases expression EXP 6480464 Ethanol results in decreased expression of PRKN protein CTD PMID:25460735 ethanol decreases expression ISO RGD:730938 6480464 Ethanol results in decreased expression of PRKN mRNA, Ethanol results in decreased expression of PRKN protein CTD PMID:35595033 ethanol multiple interactions ISO RGD:730938 6480464 PRKN protein inhibits the reaction [Ethanol results in decreased expression of FTH1 protein] more ... CTD PMID:35595033 ethanol affects expression EXP 6480464 Ethanol affects the expression of PRKN mRNA CTD PMID:30319688 fenpyroximate decreases expression ISO RGD:730938 6480464 fenpyroximate results in decreased expression of PRKN mRNA CTD PMID:33512557 folic acid increases expression EXP 6480464 Folic Acid results in increased expression of PRKN mRNA, Folic Acid results in increased expression of PRKN protein CTD PMID:26547318 fulvestrant multiple interactions ISO RGD:730938 6480464 [bisphenol A co-treated with Fulvestrant] results in increased methylation of PRKN gene CTD PMID:31601247 furan increases methylation ISO RGD:61797 6480464 furan results in increased methylation of PRKN gene CTD PMID:22079235 furosemide multiple interactions ISO RGD:61797 6480464 [Drinking Water deficiency co-treated with Furosemide co-treated with iodixanol] results in increased expression of PRKN protein CTD PMID:29860548 Genipin multiple interactions EXP 6480464 genipin inhibits the reaction [[Blood Glucose deficiency co-treated with Oxygen deficiency] results in decreased expression of PRKN protein], sirtinol inhibits the reaction [genipin inhibits the reaction [[Blood Glucose deficiency co-treated with Oxygen deficiency] results in decreased expression of PRKN protein]] CTD PMID:28477916 glucose decreases expression ISO RGD:61797 6480464 Glucose results in decreased expression of PRKN protein CTD PMID:35243728 glucose multiple interactions ISO RGD:61797 6480464 Inositol inhibits the reaction [Glucose results in decreased expression of PRKN protein] CTD PMID:35243728 glutathione affects abundance EXP 6480464 PRKN protein affects the abundance of Glutathione CTD PMID:12915482 Honokiol multiple interactions ISO RGD:61797 6480464 honokiol inhibits the reaction [amyloid beta-protein (1-42) results in decreased expression of PRKN protein], SIRT3 protein affects the reaction [honokiol inhibits the reaction [amyloid beta-protein (1-42) results in decreased expression of PRKN protein]] CTD PMID:34752757 hydrogen peroxide increases expression ISO RGD:61797 6480464 Hydrogen Peroxide results in increased expression of PRKN mRNA, Hydrogen Peroxide results in increased expression of PRKN protein CTD PMID:25787151 hydrogen peroxide affects localization EXP 6480464 Hydrogen Peroxide affects the localization of PRKN protein CTD PMID:22872702 hydrogen peroxide multiple interactions EXP 6480464 PRKN gene mutant form inhibits the reaction [Hydrogen Peroxide affects the localization of PARK7 protein] CTD PMID:22872702 indole-3-methanol affects expression ISO RGD:61797 6480464 indole-3-carbinol affects the expression of PRKN mRNA CTD PMID:21396975 indometacin multiple interactions EXP 6480464 Indomethacin promotes the reaction [PRKN gene mutant form results in increased susceptibility to Rotenone] CTD PMID:16573651 inositol multiple interactions ISO RGD:61797 6480464 Inositol inhibits the reaction [Glucose results in decreased expression of PRKN protein] CTD PMID:35243728 iodixanol multiple interactions ISO RGD:61797 6480464 [Drinking Water deficiency co-treated with Furosemide co-treated with iodixanol] results in increased expression of PRKN protein CTD PMID:29860548 ketoconazole increases response to substance ISO RGD:61797 6480464 PRKN protein results in increased susceptibility to Ketoconazole CTD PMID:25787151 ketoconazole increases expression ISO RGD:61797 6480464 Ketoconazole results in increased expression of PRKN mRNA, Ketoconazole results in increased expression of PRKN protein CTD PMID:25787151 ketoconazole multiple interactions ISO RGD:61797 6480464 1 more ... CTD PMID:25787151 Lasiocarpine decreases expression ISO RGD:730938 6480464 lasiocarpine results in decreased expression of PARK2 mRNA, lasiocarpine results in decreased expression of PRKN mRNA CTD PMID:32234424 , PMID:35690182 lead diacetate multiple interactions EXP 6480464 lead acetate results in increased phosphorylation of and affects the localization of PRKN protein CTD PMID:29660402 lead diacetate affects localization ISO RGD:730938 6480464 lead acetate affects the localization of PRKN protein CTD PMID:29660402 linsidomine increases expression ISO RGD:730938 6480464 linsidomine results in increased expression of PRKN protein CTD PMID:12880480 linsidomine multiple interactions ISO RGD:730938 6480464 Selegiline inhibits the reaction [linsidomine results in increased expression of PRKN protein] CTD PMID:12880480 linuron multiple interactions ISO RGD:61797 6480464 [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of PRKN mRNA CTD PMID:25607892 lipopolysaccharide increases expression ISO RGD:61797 6480464 Lipopolysaccharides results in increased expression of PRKN protein CTD PMID:30084861 luteolin multiple interactions EXP 6480464 [Rotenone co-treated with Luteolin] results in increased expression of PRKN mRNA, Luteolin inhibits the reaction [Rotenone results in decreased expression of PRKN mRNA] CTD PMID:30207190 maneb multiple interactions EXP 6480464 3-bromo-7-nitroindazole inhibits the reaction [[Paraquat co-treated with Maneb] results in increased nitrosation of PRKN protein] more ... CTD PMID:22563483 , PMID:23985028 manganese atom decreases expression ISO RGD:61797 6480464 Manganese results in decreased expression of PRKN mRNA CTD PMID:19781568 manganese atom decreases expression ISO RGD:730938 6480464 Manganese results in decreased expression of PRKN mRNA CTD PMID:28826884 manganese atom increases expression ISO RGD:61797 6480464 Manganese results in increased expression of PRKN protein CTD PMID:20798247 manganese atom affects response to substance ISO RGD:730938 6480464 PRKN gene mutant form affects the susceptibility to Manganese CTD PMID:22841634 manganese atom decreases transport ISO RGD:730938 6480464 PRKN protein results in decreased transport of Manganese CTD PMID:20089134 manganese(0) decreases expression ISO RGD:61797 6480464 Manganese results in decreased expression of PRKN mRNA CTD PMID:19781568 manganese(0) decreases expression ISO RGD:730938 6480464 Manganese results in decreased expression of PRKN mRNA CTD PMID:28826884 manganese(0) increases expression ISO RGD:61797 6480464 Manganese results in increased expression of PRKN protein CTD PMID:20798247 manganese(0) affects response to substance ISO RGD:730938 6480464 PRKN gene mutant form affects the susceptibility to Manganese CTD PMID:22841634 manganese(0) decreases transport ISO RGD:730938 6480464 PRKN protein results in decreased transport of Manganese CTD PMID:20089134 manganese(II) chloride increases expression ISO RGD:61797 6480464 manganese chloride results in increased expression of PRKN protein CTD PMID:20798247 manganese(II) chloride decreases expression ISO RGD:730938 6480464 manganese chloride results in decreased expression of PRKN mRNA CTD PMID:27913844 manganese(II) chloride increases methylation ISO RGD:730938 6480464 manganese chloride results in increased methylation of PRKN gene CTD PMID:27913844 manganese(II) chloride decreases expression ISO RGD:61797 6480464 manganese chloride results in decreased expression of PRKN mRNA CTD PMID:20635692 melatonin multiple interactions ISO RGD:61797 6480464 Melatonin inhibits the reaction [Carbon Tetrachloride results in decreased expression of PRKN protein] CTD PMID:26882442 methamphetamine decreases expression ISO RGD:61797 6480464 Methamphetamine results in decreased expression of PRKN protein CTD PMID:28661099 , PMID:31059759 methamphetamine multiple interactions ISO RGD:730938 6480464 CEBPB protein affects the reaction [Methamphetamine results in decreased expression of PRKN protein] more ... CTD PMID:31059759 methamphetamine decreases expression ISO RGD:730938 6480464 Methamphetamine results in decreased expression of PRKN protein CTD PMID:31059759 methamphetamine multiple interactions ISO RGD:61797 6480464 CEBPB protein affects the reaction [Methamphetamine results in decreased expression of PRKN protein] CTD PMID:31059759 methapyrilene increases methylation ISO RGD:730938 6480464 Methapyrilene results in increased methylation of PRKN intron CTD PMID:30157460 methylmercury chloride increases expression EXP 6480464 methylmercuric chloride results in increased expression of PRKN mRNA CTD PMID:20061341 miconazole increases expression ISO RGD:61797 6480464 Miconazole results in increased expression of PRKN mRNA CTD PMID:22262564 minocycline multiple interactions EXP 6480464 Minocycline inhibits the reaction [PRKN gene mutant form results in increased susceptibility to Rotenone] CTD PMID:16573651 N-acetyl-L-cysteine multiple interactions ISO RGD:730938 6480464 Acetylcysteine inhibits the reaction [quinone results in increased expression of PRKN protein] CTD PMID:29567065 N-acetyl-L-cysteine multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [[Aluminum Chloride results in increased abundance of Aluminum] which results in increased expression of PRKN mRNA] more ... CTD PMID:22872702 more ... N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal multiple interactions ISO RGD:730938 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [[Sorafenib co-treated with PRKN protein] results in decreased expression of MCL1 protein] more ... CTD PMID:20089134 more ... N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal affects expression ISO RGD:730938 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde affects the expression of PRKN protein alternative form CTD PMID:28688199 N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal decreases expression ISO RGD:730938 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of PRKN protein CTD PMID:28688199 N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal decreases expression ISO RGD:61797 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased expression of PRKN mRNA CTD PMID:18586549 N-methyl-4-phenylpyridinium increases expression ISO RGD:730938 6480464 1-Methyl-4-phenylpyridinium results in increased expression of PRKN mRNA CTD PMID:16987221 N-methyl-4-phenylpyridinium decreases expression ISO RGD:730938 6480464 1-Methyl-4-phenylpyridinium results in decreased expression of PRKN protein CTD PMID:28688199 N-methyl-4-phenylpyridinium multiple interactions ISO RGD:730938 6480464 Tretinoin affects the reaction [1-Methyl-4-phenylpyridinium affects the expression of PRKN protein alternative form] CTD PMID:28688199 N-methyl-4-phenylpyridinium affects expression ISO RGD:730938 6480464 1-Methyl-4-phenylpyridinium affects the expression of PRKN protein alternative form CTD PMID:28688199 N-methyl-4-phenylpyridinium affects localization EXP 6480464 1-Methyl-4-phenylpyridinium affects the localization of PRKN protein CTD PMID:22872702 N-methyl-4-phenylpyridinium increases expression EXP 6480464 1-Methyl-4-phenylpyridinium results in increased expression of PRKN mRNA CTD PMID:26558463 N-Nitrosopyrrolidine decreases expression ISO RGD:730938 6480464 N-Nitrosopyrrolidine results in decreased expression of PARK2 mRNA, N-Nitrosopyrrolidine results in decreased expression of PRKN mRNA CTD PMID:32234424 , PMID:35690182 nicotine decreases expression ISO RGD:730938 6480464 Nicotine results in decreased expression of PRKN mRNA CTD PMID:16949557 O-acetyl-L-carnitine multiple interactions EXP 6480464 Acetylcarnitine inhibits the reaction [Cadmium results in increased expression of PRKN] CTD PMID:25464205 O-methyleugenol decreases expression ISO RGD:730938 6480464 methyleugenol results in decreased expression of PARK2 mRNA, methyleugenol results in decreased expression of PRKN mRNA CTD PMID:32234424 , PMID:35690182 oligomycin A multiple interactions ISO RGD:730938 6480464 [oligomycin A co-treated with Antimycin A] affects the localization of PRKN protein, PINK1 protein affects the reaction [[oligomycin A co-treated with Antimycin A] affects the localization of PRKN protein] CTD PMID:28366621 oxidopamine decreases reaction ISO RGD:730938 6480464 PRKN protein inhibits the reaction Oxidopamine CTD PMID:15198987 oxidopamine multiple interactions ISO RGD:730938 6480464 PINK1 protein affects the reaction [salvin inhibits the reaction [Oxidopamine results in decreased expression of PRKN protein]] more ... CTD PMID:28688199 , PMID:30707903 oxidopamine decreases expression ISO RGD:730938 6480464 Oxidopamine results in decreased expression of PRKN protein CTD PMID:28688199 , PMID:30707903 oxidopamine affects expression ISO RGD:730938 6480464 Oxidopamine affects the expression of PRKN protein alternative form CTD PMID:28688199 oxidopamine multiple interactions EXP 6480464 PRKN protein inhibits the reaction [Oxidopamine results in decreased expression of TH protein] CTD PMID:16914382 oxidopamine multiple interactions ISO RGD:61797 6480464 isoquercitrin inhibits the reaction [Oxidopamine results in increased expression of PRKN mRNA] more ... CTD PMID:25129099 oxidopamine increases expression ISO RGD:61797 6480464 Oxidopamine results in increased expression of PRKN mRNA CTD PMID:25129099 paracetamol multiple interactions ISO RGD:61797 6480464 [bisphenol A co-treated with enzacamene co-treated with octylmethoxycinnamate co-treated with butylparaben co-treated with Androgen Antagonists co-treated with Acetaminophen] results in decreased expression of PRKN mRNA CTD PMID:25607892 paracetamol multiple interactions EXP 6480464 [Acetaminophen co-treated with PRKN gene mutant form] results in decreased phosphorylation of GYS1 protein more ... CTD PMID:25752611 , PMID:33271250 paracetamol decreases response to substance EXP 6480464 PRKN gene mutant form results in decreased susceptibility to Acetaminophen CTD PMID:25752611 paracetamol affects localization EXP 6480464 Acetaminophen affects the localization of PRKN protein CTD PMID:25752611 paracetamol increases expression EXP 6480464 Acetaminophen results in increased expression of PRKN protein CTD PMID:33271250 paraquat decreases expression EXP 6480464 Paraquat results in decreased expression of PRKN mRNA CTD PMID:22563483 paraquat decreases expression ISO RGD:730938 6480464 Paraquat results in decreased expression of PRKN mRNA CTD PMID:34097952 paraquat increases phosphorylation ISO RGD:730938 6480464 Paraquat results in increased phosphorylation of PRKN protein CTD PMID:33383311 paraquat multiple interactions ISO RGD:730938 6480464 Antigens more ... CTD PMID:30144575 more ... paraquat multiple interactions EXP 6480464 3-bromo-7-nitroindazole inhibits the reaction [[Paraquat co-treated with Maneb] results in increased nitrosation of PRKN protein] more ... CTD PMID:22563483 , PMID:23985028 picoxystrobin decreases expression ISO RGD:730938 6480464 picoxystrobin results in decreased expression of PRKN mRNA CTD PMID:33512557 poly(vinylpyrrolidone) multiple interactions EXP 6480464 [Silver Compounds co-treated with Povidone] results in increased expression of PRKN protein CTD PMID:35697184 prochloraz multiple interactions ISO RGD:61797 6480464 [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of PRKN mRNA CTD PMID:25607892 procymidone multiple interactions ISO RGD:61797 6480464 [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of PRKN mRNA CTD PMID:25607892 pyrimidifen decreases expression ISO RGD:730938 6480464 pyrimidifen results in decreased expression of PRKN mRNA CTD PMID:33512557 quercetin 3-O-beta-D-glucofuranoside multiple interactions ISO RGD:61797 6480464 isoquercitrin inhibits the reaction [Oxidopamine results in increased expression of PRKN mRNA] CTD PMID:25129099 quercetin 3-O-beta-D-glucopyranoside multiple interactions ISO RGD:61797 6480464 isoquercitrin inhibits the reaction [Oxidopamine results in increased expression of PRKN mRNA] CTD PMID:25129099 reactive oxygen species decreases abundance ISO RGD:730938 6480464 PRKN protein results in decreased abundance of Reactive Oxygen Species CTD PMID:15198987 , PMID:31926197 reactive oxygen species multiple interactions ISO RGD:730938 6480464 PRKN protein inhibits the reaction [Dopamine results in increased abundance of Reactive Oxygen Species] CTD PMID:15198987 resveratrol multiple interactions ISO RGD:730938 6480464 PRKN gene mutant form affects the reaction [resveratrol results in increased expression of COX1 mRNA] more ... CTD PMID:24582596 resveratrol increases expression ISO RGD:61797 6480464 Resveratrol results in increased expression of PRKN protein CTD PMID:32619457 resveratrol multiple interactions ISO RGD:61797 6480464 [Resveratrol co-treated with Benzo(a)pyrene] results in increased expression of PRKN protein CTD PMID:32619457 rimonabant decreases response to substance EXP 6480464 PRKN results in decreased susceptibility to Rimonabant CTD PMID:15882845 rimonabant multiple interactions ISO RGD:61797 6480464 Rimonabant affects the reaction [PRKN mutant form affects the activity of TH protein] CTD PMID:15882845 rotenone multiple interactions ISO RGD:730938 6480464 DNM1L protein affects the reaction [Rotenone affects the localization of PRKN protein] more ... CTD PMID:19741132 , PMID:32001317 rotenone multiple interactions ISO RGD:61797 6480464 [Particulate Matter co-treated with Rotenone] results in decreased expression of PRKN protein more ... CTD PMID:33823232 , PMID:35104487 rotenone decreases expression EXP 6480464 Rotenone results in decreased expression of PRKN mRNA CTD PMID:30207190 rotenone affects expression ISO RGD:61797 6480464 Rotenone affects the expression of PRKN mRNA CTD PMID:31814881 rotenone affects localization ISO RGD:730938 6480464 Rotenone affects the localization of PRKN protein CTD PMID:32001317 rotenone decreases expression ISO RGD:61797 6480464 Rotenone results in decreased expression of PRKN mRNA, Rotenone results in decreased expression of PRKN protein CTD PMID:32392329 , PMID:35104487 rotenone affects localization EXP 6480464 Rotenone affects the localization of PRKN protein CTD PMID:22872702 rotenone multiple interactions EXP 6480464 [Particulate Matter co-treated with Rotenone] results in decreased expression of PRKN protein more ... CTD PMID:16573651 more ... rotenone decreases response to substance EXP 6480464 PRKN protein results in decreased susceptibility to Rotenone CTD PMID:16517603 rotenone increases response to substance EXP 6480464 PRKN gene mutant form results in increased susceptibility to Rotenone CTD PMID:16517603 , PMID:16573651 rotenone decreases expression ISO RGD:730938 6480464 Rotenone results in decreased expression of PRKN mRNA, Rotenone results in decreased expression of PRKN protein CTD PMID:31926197 more ... rotenone affects response to substance ISO RGD:730938 6480464 PRKN protein affects the susceptibility to Rotenone CTD PMID:20940149 rotenone decreases response to substance ISO RGD:730938 6480464 PRKN protein results in decreased susceptibility to Rotenone CTD PMID:17687034 , PMID:19741132 rotenone increases response to substance ISO RGD:730938 6480464 PRKN gene mutant form results in increased susceptibility to Rotenone CTD PMID:17687034 rutin multiple interactions ISO RGD:61797 6480464 Rutin inhibits the reaction [Oxidopamine results in increased expression of PRKN mRNA] CTD PMID:25129099 S-nitrosoglutathione multiple interactions ISO RGD:730938 6480464 [S-Nitrosoglutathione results in increased nitrosation of PRKN protein] inhibits the reaction [PRKN protein binds to TP53 promoter] more ... CTD PMID:23985028 silibinin multiple interactions ISO RGD:730938 6480464 Silybin inhibits the reaction [Acetaldehyde results in decreased expression of PRKN mRNA] more ... CTD PMID:35595033 silicon dioxide decreases expression ISO RGD:61797 6480464 Silicon Dioxide analog results in decreased expression of PRKN protein CTD PMID:27613482 sirolimus multiple interactions ISO RGD:61797 6480464 Sirolimus inhibits the reaction [[Particulate Matter co-treated with Rotenone] results in decreased expression of PRKN protein] CTD PMID:33823232 sirolimus multiple interactions EXP 6480464 Sirolimus inhibits the reaction [[Particulate Matter co-treated with Rotenone] results in decreased expression of PRKN protein], Sirolimus inhibits the reaction [Carbon Tetrachloride results in increased expression of PRKN protein] CTD PMID:33823232 , PMID:35405287 sirtinol multiple interactions EXP 6480464 sirtinol inhibits the reaction [genipin inhibits the reaction [[Blood Glucose deficiency co-treated with Oxygen deficiency] results in decreased expression of PRKN protein]] CTD PMID:28477916 sodium arsenite affects methylation ISO RGD:730938 6480464 sodium arsenite affects the methylation of PRKN gene CTD PMID:28589171 sodium arsenite decreases expression ISO RGD:61797 6480464 sodium arsenite results in decreased expression of PRKN protein CTD PMID:30551535 sorafenib increases ubiquitination ISO RGD:730938 6480464 sorafenib results in increased ubiquitination of PRKN protein CTD PMID:28673964 sorafenib increases ubiquitination EXP 6480464 sorafenib results in increased ubiquitination of PRKN protein CTD PMID:28673964 sorafenib affects response to substance EXP 6480464 PRKN protein affects the susceptibility to sorafenib CTD PMID:28673964 sorafenib multiple interactions ISO RGD:730938 6480464 [sorafenib co-treated with PRKN protein] results in decreased expression of CASP3 protein more ... CTD PMID:28673964 sorafenib affects localization ISO RGD:730938 6480464 sorafenib affects the localization of PRKN protein CTD PMID:28673964 sunitinib increases expression ISO RGD:730938 6480464 Sunitinib results in increased expression of PRKN mRNA CTD PMID:31533062 T-2 toxin increases expression ISO RGD:61797 6480464 T-2 Toxin results in increased expression of PRKN mRNA, T-2 Toxin results in increased expression of PRKN protein CTD PMID:29870751 taurine multiple interactions ISO RGD:61797 6480464 Taurine inhibits the reaction [Arsenic Trioxide results in decreased expression of PRKN protein] CTD PMID:30551535 tebufenpyrad decreases expression ISO RGD:730938 6480464 4-chloro-N-((4-(1, 1-dimethylethyl)phenyl)methyl)-3-ethyl-1-methyl-1H-pyrazole-5-carboxamide results in decreased expression of PRKN mRNA CTD PMID:33512557 tenofovir disoproxil fumarate multiple interactions ISO RGD:730938 6480464 [Emtricitabine co-treated with Tenofovir] results in decreased expression of PRKN protein CTD PMID:31545371 tetrachloromethane multiple interactions ISO RGD:61797 6480464 Melatonin inhibits the reaction [Carbon Tetrachloride results in decreased expression of PRKN protein] CTD PMID:26882442 tetrachloromethane multiple interactions EXP 6480464 Sirolimus inhibits the reaction [Carbon Tetrachloride results in increased expression of PRKN protein] CTD PMID:35405287 tetrachloromethane increases expression EXP 6480464 Carbon Tetrachloride results in increased expression of PRKN protein CTD PMID:35405287 tetrachloromethane decreases expression ISO RGD:61797 6480464 Carbon Tetrachloride results in decreased expression of PRKN protein CTD PMID:26882442 thioacetamide decreases expression ISO RGD:61797 6480464 Thioacetamide results in decreased expression of PRKN mRNA CTD PMID:23411599 Tiron multiple interactions ISO RGD:61797 6480464 1 more ... CTD PMID:25787151 Tiron multiple interactions EXP 6480464 1 more ... CTD PMID:22872702 titanium dioxide increases expression ISO RGD:730938 6480464 titanium dioxide results in increased expression of PRKN mRNA CTD PMID:30273564 trans-piceid affects response to substance ISO RGD:730938 6480464 PRKN protein affects the susceptibility to polydatin CTD PMID:31926197 trans-piceid multiple interactions ISO RGD:730938 6480464 [PRKN protein affects the susceptibility to polydatin] which results in increased expression of PARK7 protein CTD PMID:31926197 trifloxystrobin increases expression ISO RGD:730938 6480464 trifloxystrobin results in increased expression of PRKN protein CTD PMID:27853101 trifloxystrobin multiple interactions ISO RGD:730938 6480464 MitoTEMPO inhibits the reaction [trifloxystrobin results in increased expression of PRKN protein] CTD PMID:27853101 trifluoperazine affects localization ISO RGD:730938 6480464 Trifluoperazine affects the localization of PRKN protein CTD PMID:28366621 trifluoperazine multiple interactions ISO RGD:730938 6480464 PRKN protein affects the reaction [Trifluoperazine affects the localization of PRKN protein] CTD PMID:28366621 trimellitic anhydride decreases expression EXP 6480464 trimellitic anhydride results in decreased expression of PRKN mRNA CTD PMID:19042947 tubocurarine decreases expression ISO RGD:730938 6480464 Tubocurarine results in decreased expression of PRKN mRNA CTD PMID:16949557 valproic acid decreases methylation ISO RGD:730938 6480464 Valproic Acid results in decreased methylation of PRKN gene CTD PMID:29154799 venlafaxine hydrochloride multiple interactions ISO RGD:61797 6480464 Chloroquine inhibits the reaction [Venlafaxine Hydrochloride inhibits the reaction [Rotenone results in decreased expression of PRKN protein]], Venlafaxine Hydrochloride inhibits the reaction [Rotenone results in decreased expression of PRKN protein] CTD PMID:35104487 vinclozolin multiple interactions ISO RGD:61797 6480464 [Dibutyl Phthalate co-treated with Diethylhexyl Phthalate co-treated with vinclozolin co-treated with prochloraz co-treated with procymidone co-treated with Linuron co-treated with epoxiconazole co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of PRKN mRNA CTD PMID:25607892