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Gene: Dapk1 (death associated protein kinase 1) Mus musculus
Symbol: Dapk1
Name: death associated protein kinase 1
Description: Exhibits ATP binding activity; calmodulin binding activity; and protein kinase activity. Involved in several processes, including cellular response to interferon-gamma; extrinsic apoptotic signaling pathway via death domain receptors; and regulation of signal transduction. Localizes to cytoplasm. Is expressed in several structures, including cardiovascular system; central nervous system; genitourinary system; gut; and sensory organ. Human ortholog(s) of this gene implicated in urinary bladder cancer. Orthologous to human DAPK1 (death associated protein kinase 1); PARTICIPATES IN type II interferon signaling pathway; urinary bladder cancer pathway; INTERACTS WITH 1,2-dimethylhydrazine; 2,2',4,4',5,5'-hexachlorobiphenyl; 2,2',5,5'-tetrachlorobiphenyl.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 2310039H24Rik; 2810425C21Rik; AI642003; D13Ucl; D13Ucla1; DAP kinase 1; DAP-; DAP-Kinase; death-associated protein kinase 1
Homo sapiens (human) : DAPK1 (death associated protein kinase 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Dapk1 (death associated protein kinase 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dapk1 (death associated protein kinase 1)
Pan paniscus (bonobo/pygmy chimpanzee) : DAPK1 (death associated protein kinase 1)
Canis lupus familiaris (dog) : DAPK1 (death associated protein kinase 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dapk1 (death associated protein kinase 1)
Sus scrofa (pig) : DAPK1 (death associated protein kinase 1)
Chlorocebus sabaeus (African green monkey) : DAPK1 (death associated protein kinase 1)
Heterocephalus glaber (naked mole-rat) : Dapk1 (death associated protein kinase 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl1360,601,947 - 60,763,191 (+)EnsemblGRCm38mm10GRCm38
GRCm381360,601,723 - 60,763,191 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371360,703,308 - 60,864,547 (+)NCBIGRCm37mm9NCBIm37
MGSCv361360,612,049 - 60,772,424 (+)NCBImm8
Celera1361,661,141 - 61,823,107 (+)NCBICelera
Cytogenetic Map13B2NCBI
cM Map1332.53NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Dapk1
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1323187
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-09-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.