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Gene: Dspp (dentin sialophosphoprotein) Mus musculus
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Symbol: Dspp
Name: dentin sialophosphoprotein
RGD ID: 10493
Description: Predicted to have collagen binding activity. Involved in several processes, including animal organ morphogenesis; epithelial cell differentiation; and negative regulation of cell population proliferation. Localizes to extracellular matrix; extracellular space; and nucleus. Is expressed in alimentary system; central nervous system; lung; male reproductive gland or organ; and metanephros. Used to study dentinogenesis imperfecta and periodontal disease. Human ortholog(s) of this gene implicated in dentinogenesis imperfecta. Orthologous to human DSPP (dentin sialophosphoprotein).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: D; dentin matrix protein 3; Dmp; DMP-3; Dmp2; Dmp3; Dpp; Dsp; MGC124498
Orthologs:
Homo sapiens (human) : DSPP (dentin sialophosphoprotein)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Dspp (dentin sialophosphoprotein)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dspp (dentin sialophosphoprotein)
Pan paniscus (bonobo/pygmy chimpanzee) : DSPP (dentin sialophosphoprotein)
Canis lupus familiaris (dog) : DSPP (dentin sialophosphoprotein)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dspp (dentin sialophosphoprotein)
Sus scrofa (pig) : DSPP (dentin sialophosphoprotein)
Chlorocebus sabaeus (African green monkey) : DSPP (dentin sialophosphoprotein)
Heterocephalus glaber (naked mole-rat) : Dspp (dentin sialophosphoprotein)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 Ensembl5104,170,712 - 104,180,127 (+)EnsemblGRCm38mm10GRCm38
GRCm385104,170,703 - 104,180,127 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv375104,599,731 - 104,609,146 (+)NCBIGRCm37mm9NCBIm37
MGSCv365104,411,005 - 104,420,429 (+)NCBImm8
Celera5101,476,457 - 101,494,758 (+)NCBICelera
Cytogenetic Map5E5NCBI
cM Map550.59NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Dspp
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 10493
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-09-09
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.