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Gene: Dspp (dentin sialophosphoprotein) Mus musculus
Symbol: Dspp
Name: dentin sialophosphoprotein
RGD ID: 10493
Description: Predicted to have collagen binding activity. Involved in several processes, including animal organ morphogenesis; epithelial cell differentiation; and negative regulation of cell population proliferation. Localizes to extracellular matrix; extracellular space; and nucleus. Is expressed in alimentary system; central nervous system; lung; male reproductive gland or organ; and metanephros. Used to study dentinogenesis imperfecta and periodontal disease. Human ortholog(s) of this gene implicated in dentinogenesis imperfecta. Orthologous to human DSPP (dentin sialophosphoprotein).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: D; dentin matrix protein 3; Dmp; DMP-3; Dmp2; Dmp3; Dpp; Dsp; MGC124498
Homo sapiens (human) : DSPP (dentin sialophosphoprotein)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Dspp (dentin sialophosphoprotein)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dspp (dentin sialophosphoprotein)
Pan paniscus (bonobo/pygmy chimpanzee) : DSPP (dentin sialophosphoprotein)
Canis lupus familiaris (dog) : DSPP (dentin sialophosphoprotein)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dspp (dentin sialophosphoprotein)
Sus scrofa (pig) : DSPP (dentin sialophosphoprotein)
Chlorocebus sabaeus (African green monkey) : DSPP (dentin sialophosphoprotein)
Heterocephalus glaber (naked mole-rat) : Dspp (dentin sialophosphoprotein)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm38.p6 Ensembl5104,170,712 - 104,180,127 (+)EnsemblGRCm38mm10GRCm38
GRCm385104,170,703 - 104,180,127 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv375104,599,731 - 104,609,146 (+)NCBIGRCm37mm9NCBIm37
MGSCv365104,411,005 - 104,420,429 (+)NCBImm8
Celera5101,476,457 - 101,494,758 (+)NCBICelera
Cytogenetic Map5E5NCBI
cM Map550.59NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
More on Dspp
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 10493
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-09-09
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.