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Gene: Foxm1 (forkhead box M1) Mus musculus
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Symbol: Foxm1
Name: forkhead box M1
RGD ID: 62099
Description: Exhibits transcription regulatory region sequence-specific DNA binding activity. Involved in several processes, including DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator; positive regulation of nucleobase-containing compound metabolic process; and vasculogenesis. Localizes to nucleus. Is expressed in several structures, including alimentary system; brain; genitourinary system; respiratory system; and sensory organ. Used to study hepatocellular carcinoma; lung cancer; and type 2 diabetes mellitus. Orthologous to human FOXM1 (forkhead box M1); INTERACTS WITH 1,1-dichloroethene; 1,2-dimethylhydrazine; 1-naphthyl isothiocyanate.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AA408308; AW554517; BB238854; D1Mgi5; expressed sequence BB238854; Fkh16; forkhead box protein M1; forkhead homolog 16; Foxm1b; HFH-11B; MPHOSPH2; Mpm; Mpm2; Trid; trident; W; WIN; winged-helix transcription factor Trident
Orthologs:
Homo sapiens (human) : FOXM1 (forkhead box M1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Foxm1 (forkhead box M1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Foxm1 (forkhead box M1)
Pan paniscus (bonobo/pygmy chimpanzee) : FOXM1 (forkhead box M1)
Canis lupus familiaris (dog) : FOXM1 (forkhead box M1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Foxm1 (forkhead box M1)
Sus scrofa (pig) : FOXM1 (forkhead box M1)
Chlorocebus sabaeus (African green monkey) : FOXM1 (forkhead box M1)
Heterocephalus glaber (naked mole-rat) : Foxm1 (forkhead box M1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38.p6 Ensembl6128,362,967 - 128,376,146 (+)EnsemblGRCm38mm10GRCm38
GRCm386128,362,994 - 128,375,886 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv376128,313,012 - 128,325,904 (+)NCBIGRCm37mm9NCBIm37
MGSCv366128,328,595 - 128,341,501 (+)NCBImm8
Celera6130,039,894 - 130,052,715 (+)NCBICelera
Cytogenetic Map6F3NCBI
cM Map662.98NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
Nomenclature History
 
More on Foxm1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 62099
Created: 2001-04-11
Species: Mus musculus
Last Modified: 2020-09-09
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.