mt-Nd5 (NADH dehydrogenase 5, mitochondrial) - Rat Genome Database

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Gene: mt-Nd5 (NADH dehydrogenase 5, mitochondrial) Mus musculus
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Symbol: mt-Nd5
Name: NADH dehydrogenase 5, mitochondrial
RGD ID: 736401
MGI Page MGI
Description: Contributes to NADH dehydrogenase (ubiquinone) activity. Predicted to be involved in electron transport coupled proton transport; mitochondrial electron transport, NADH to ubiquinone; and mitochondrial respiratory chain complex I assembly. Located in mitochondrion. Is expressed in central nervous system; heart; liver; metanephros; and retina. Human ortholog(s) of this gene implicated in Leber hereditary optic neuropathy; Leigh disease; and MELAS syndrome. Orthologous to human MT-ND5 (mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 5); PARTICIPATES IN oxidative phosphorylation pathway; Parkinson's disease pathway; INTERACTS WITH benzo[b]fluoranthene; bisphenol A; citraconic acid.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: NADH dehydrogenase subunit 5
RGD Orthologs
Human
Rat
Dog
Pig
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39MT11,742 - 13,565 (+)NCBIGRCm39mm39
GRCm39 EnsemblMT11,742 - 13,565 (+)Ensembl
GRCm38MT11,742 - 13,565 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblMT11,742 - 13,565 (+)EnsemblGRCm38mm10GRCm38
MGSCv37MT11,742 - 13,565 (+)NCBIGRCm37mm9NCBIm37


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Additional References at PubMed
PMID:18614015   PMID:18614564   PMID:18729827   PMID:19037013   PMID:21873635   PMID:26465331   PMID:30550785   PMID:31337008  


Genomics

Comparative Map Data
mt-Nd5
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39MT11,742 - 13,565 (+)NCBIGRCm39mm39
GRCm39 EnsemblMT11,742 - 13,565 (+)Ensembl
GRCm38MT11,742 - 13,565 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 EnsemblMT11,742 - 13,565 (+)EnsemblGRCm38mm10GRCm38
MGSCv37MT11,742 - 13,565 (+)NCBIGRCm37mm9NCBIm37
MT-ND5
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 EnsemblMT12,337 - 14,148 (+)EnsemblGRCh38hg38GRCh38
GRCh38MT12,337 - 14,148 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37MT12,337 - 14,148 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36MT12,338 - 14,149 (+)NCBINCBI36hg18NCBI36
Mt-nd5
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2MT11,736 - 13,565 (+)NCBImRatBN7.2
mRatBN7.2 EnsemblMT11,736 - 13,565 (+)Ensembl
Rnor_6.0MT11,736 - 13,565 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 EnsemblMT11,736 - 13,565 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0MT11,736 - 13,565 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4MT11,736 - 13,565 (+)NCBIRGSC3.4rn4RGSC3.4
Cytogenetic MapMT NCBI
MT-ND5
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1MT11,778 - 13,598 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 EnsemblMT11,778 - 13,598 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_TashaMT11,778 - 13,598 (+)NCBI
MT-ND5
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 EnsemblMT12,935 - 14,755 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1MT12,935 - 14,755 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2MT12,935 - 14,755 (+)NCBISscrofa10.2Sscrofa10.2susScr3

Position Markers
RH136205  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38480,003,768 - 80,003,953UniSTSGRCm38
GRCm38MT13,924 - 14,109UniSTSGRCm38
MGSCv37479,649,672 - 79,649,857UniSTSGRCm37
MGSCv37MT13,924 - 14,109UniSTSGRCm37
Celera478,553,237 - 78,553,422UniSTS
RH136233  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38124,611,744 - 24,611,936UniSTSGRCm38
GRCm38MT10,641 - 10,833UniSTSGRCm38
MGSCv37124,618,583 - 24,618,775UniSTSGRCm37
MGSCv37MT10,641 - 10,833UniSTSGRCm37
RH136257  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381385,126,989 - 85,127,171UniSTSGRCm38
GRCm38MT12,790 - 12,972UniSTSGRCm38
MGSCv371385,266,594 - 85,266,776UniSTSGRCm37
MGSCv37MT12,790 - 12,972UniSTSGRCm37
Celera1387,358,885 - 87,359,067UniSTS
Cytogenetic Map13C3UniSTS
RH136274  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm381385,127,323 - 85,127,513UniSTSGRCm38
GRCm38MT12,448 - 12,638UniSTSGRCm38
MGSCv371385,266,928 - 85,267,118UniSTSGRCm37
MGSCv37MT12,448 - 12,638UniSTSGRCm37
Celera1387,359,219 - 87,359,409UniSTS
Cytogenetic Map13C3UniSTS
RH136285  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38480,003,771 - 80,003,953UniSTSGRCm38
GRCm38MT13,927 - 14,109UniSTSGRCm38
MGSCv37479,649,675 - 79,649,857UniSTSGRCm37
MGSCv37MT13,927 - 14,109UniSTSGRCm37
Celera478,553,240 - 78,553,422UniSTS
RH136370  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38480,003,767 - 80,003,952UniSTSGRCm38
GRCm38MT13,923 - 14,108UniSTSGRCm38
MGSCv37479,649,671 - 79,649,856UniSTSGRCm37
MGSCv37MT13,923 - 14,108UniSTSGRCm37
Celera478,553,236 - 78,553,421UniSTS
RH136382  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38MT13,915 - 14,109UniSTSGRCm38
MGSCv37MT13,915 - 14,109UniSTSGRCm37
RH136397  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38124,611,805 - 24,612,001UniSTSGRCm38
GRCm38MT10,576 - 10,772UniSTSGRCm38
MGSCv37124,618,644 - 24,618,840UniSTSGRCm37
MGSCv37MT10,576 - 10,772UniSTSGRCm37
RH136521  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38124,611,571 - 24,611,766UniSTSGRCm38
GRCm38MT10,811 - 11,006UniSTSGRCm38
MGSCv37124,618,410 - 24,618,605UniSTSGRCm37
MGSCv37MT10,811 - 11,006UniSTSGRCm37
RH136536  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38480,003,757 - 80,003,953UniSTSGRCm38
GRCm38MT13,913 - 14,109UniSTSGRCm38
MGSCv37479,649,661 - 79,649,857UniSTSGRCm37
MGSCv37MT13,913 - 14,109UniSTSGRCm37
Celera478,553,226 - 78,553,422UniSTS
mt-Nd6  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38MT13,614 - 13,794UniSTSGRCm38
MGSCv37MT13,614 - 13,794UniSTSGRCm37
cM MapMT83.0UniSTS
RH125467  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38124,611,740 - 24,611,985UniSTSGRCm38
GRCm38MT10,592 - 10,837UniSTSGRCm38
MGSCv37124,618,579 - 24,618,824UniSTSGRCm37
MGSCv37MT10,592 - 10,837UniSTSGRCm37
UniSTS:234089  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38MT10,139 - 10,359UniSTSGRCm38
GRCm38124,612,218 - 24,612,438UniSTSGRCm38
MGSCv37124,619,057 - 24,619,277UniSTSGRCm37
MGSCv37MT10,139 - 10,359UniSTSGRCm37
Cytogenetic Map1A3-A5UniSTS
UniSTS:234092  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38MT10,131 - 10,357UniSTSGRCm38
GRCm38124,612,220 - 24,612,446UniSTSGRCm38
MGSCv37124,619,059 - 24,619,285UniSTSGRCm37
MGSCv37MT10,131 - 10,357UniSTSGRCm37
Cytogenetic Map1A3-A5UniSTS
PMC85197P1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38480,003,229 - 80,003,459UniSTSGRCm38
GRCm38MT13,387 - 13,615UniSTSGRCm38
MGSCv37479,649,133 - 79,649,363UniSTSGRCm37
MGSCv37MT13,387 - 13,615UniSTSGRCm37
Celera478,552,698 - 78,552,928UniSTS

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:124
Count of miRNA genes:113
Interacting mature miRNAs:117
Transcripts:ENSMUST00000082418
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
GenBank Nucleotide AB049357 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ489607 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ512208 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK140457 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AP013030 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AP014540 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AP014541 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY172335 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY466499 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY533105 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY533106 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY533107 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY533108 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY999076 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EF108330 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EF108331 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EF108332 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EF108333 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EF108334 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EF108335 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EF108336 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EF108337 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EF108338 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EF108339 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EF108340 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EF108341 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EU312160 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EU312161 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EU315228 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EU315229 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EU450583 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FJ803909 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ586004 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ675026 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ675027 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ675028 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ675029 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ675030 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ675031 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HQ877407 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JF286601 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JQ003190 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KP090294 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KP260514 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KP260515 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KP260516 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KP260517 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KR020497 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KY018919 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000082418   ⟹   ENSMUSP00000081001
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 EnsemblMT11,742 - 13,565 (+)Ensembl
GRCm38.p6 EnsemblMT11,742 - 13,565 (+)Ensembl
Protein Sequences
Protein RefSeqs NP_904338 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAN85132 (Get FASTA)   NCBI Sequence Viewer  
  AAR21205 (Get FASTA)   NCBI Sequence Viewer  
  AAS01436 (Get FASTA)   NCBI Sequence Viewer  
  AAS01449 (Get FASTA)   NCBI Sequence Viewer  
  AAS01462 (Get FASTA)   NCBI Sequence Viewer  
  AAS01475 (Get FASTA)   NCBI Sequence Viewer  
  AAX83022 (Get FASTA)   NCBI Sequence Viewer  
  ABK79103 (Get FASTA)   NCBI Sequence Viewer  
  ABK79116 (Get FASTA)   NCBI Sequence Viewer  
  ABK79129 (Get FASTA)   NCBI Sequence Viewer  
  ABK79142 (Get FASTA)   NCBI Sequence Viewer  
  ABK79155 (Get FASTA)   NCBI Sequence Viewer  
  ABK79168 (Get FASTA)   NCBI Sequence Viewer  
  ABK79181 (Get FASTA)   NCBI Sequence Viewer  
  ABK79194 (Get FASTA)   NCBI Sequence Viewer  
  ABK79207 (Get FASTA)   NCBI Sequence Viewer  
  ABK79220 (Get FASTA)   NCBI Sequence Viewer  
  ABK79233 (Get FASTA)   NCBI Sequence Viewer  
  ABK79246 (Get FASTA)   NCBI Sequence Viewer  
  ABX79712 (Get FASTA)   NCBI Sequence Viewer  
  ABX79725 (Get FASTA)   NCBI Sequence Viewer  
  ABX79738 (Get FASTA)   NCBI Sequence Viewer  
  ABX79751 (Get FASTA)   NCBI Sequence Viewer  
  ACA01533 (Get FASTA)   NCBI Sequence Viewer  
  ACN91105 (Get FASTA)   NCBI Sequence Viewer  
  ADR03166 (Get FASTA)   NCBI Sequence Viewer  
  ADW83076 (Get FASTA)   NCBI Sequence Viewer  
  ADZ23173 (Get FASTA)   NCBI Sequence Viewer  
  AEN03379 (Get FASTA)   NCBI Sequence Viewer  
  AEN03392 (Get FASTA)   NCBI Sequence Viewer  
  AEN03405 (Get FASTA)   NCBI Sequence Viewer  
  AEN03418 (Get FASTA)   NCBI Sequence Viewer  
  AEN03431 (Get FASTA)   NCBI Sequence Viewer  
  AEN03444 (Get FASTA)   NCBI Sequence Viewer  
  AEV56607 (Get FASTA)   NCBI Sequence Viewer  
  AJE26566 (Get FASTA)   NCBI Sequence Viewer  
  AJK91496 (Get FASTA)   NCBI Sequence Viewer  
  AJK91509 (Get FASTA)   NCBI Sequence Viewer  
  AJK91522 (Get FASTA)   NCBI Sequence Viewer  
  AJK91535 (Get FASTA)   NCBI Sequence Viewer  
  AKS10722 (Get FASTA)   NCBI Sequence Viewer  
  ART65703 (Get FASTA)   NCBI Sequence Viewer  
  BAB13811 (Get FASTA)   NCBI Sequence Viewer  
  BAE24397 (Get FASTA)   NCBI Sequence Viewer  
  BAM93593 (Get FASTA)   NCBI Sequence Viewer  
  BAO42860 (Get FASTA)   NCBI Sequence Viewer  
  BAO42873 (Get FASTA)   NCBI Sequence Viewer  
  CAD33917 (Get FASTA)   NCBI Sequence Viewer  
  CAD54442 (Get FASTA)   NCBI Sequence Viewer  
  P03921 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: ENSMUSP00000081001   ⟸   ENSMUST00000082418
Protein Domains
NADH5_C   Proton_antipo_M   Proton_antipo_N


Additional Information

Database Acc Id Source(s)
AGR Gene MGI:102496 AgrOrtholog
Ensembl Genes ENSMUSG00000064367 Ensembl, UniProtKB/Swiss-Prot
Ensembl Protein ENSMUSP00000081001 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000082418 UniProtKB/Swiss-Prot
InterPro NADH_DH_su5_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  NADHpl_OxRdtase_5 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ND/Mrp_mem UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Proton_antipo_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:17721 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:102496 ENTREZGENE
NCBI Gene 17721 ENTREZGENE
Pfam NADH5_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Proton_antipo_M UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Proton_antipo_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen mt-Nd5 PhenoGen
TIGRFAMs NDH_I_L UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt NU5M_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q8C1H6_MOUSE UniProtKB/TrEMBL
  Q9MD82 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-05-19 mt-Nd5  NADH dehydrogenase 5, mitochondrial  ND5    Symbol and/or name change 5135510 APPROVED
2012-10-09 ND5  NADH dehydrogenase 5, mitochondrial      Symbol and/or name change 5135510 APPROVED
2011-07-27 ND5    mt-Nd5  NADH dehydrogenase 5, mitochondrial  Symbol and/or name change 5135510 APPROVED