Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: Tfrc (transferrin receptor) Mus musculus
Analyze
Symbol: Tfrc
Name: transferrin receptor
Description: Predicted to have several functions, including Hsp70 protein binding activity; chaperone binding activity; and protein homodimerization activity. Involved in several processes, including cellular response to leukemia inhibitory factor; positive regulation of bone resorption; and positive regulation of lymphocyte proliferation. Localizes to several cellular components, including the HFE-transferrin receptor complex; endosome; and extracellular exosome. Human ortholog(s) of this gene implicated in breast carcinoma; multiple myeloma; ovarian cancer; and primary immunodeficiency disease. Is expressed in several structures, including alimentary system; extraembryonic component; liver; lung; and meninges. Orthologous to human TFRC (transferrin receptor).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 2610028K12Rik; AI195355; AI426448; AU015758; CD71; E430033M20Rik; mammary tumor virus receptor 1; Mtvr-1; Mtvr1; p90; TFR; TFR1; TR; transferrin receptor protein 1; Trfr
Orthologs:
Homo sapiens (human) : TFRC (transferrin receptor)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Tfrc (transferrin receptor)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Tfrc (transferrin receptor)
Pan paniscus (bonobo/pygmy chimpanzee) : TFRC (transferrin receptor)
Canis lupus familiaris (dog) : TFRC (transferrin receptor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Tfrc (transferrin receptor)
Sus scrofa (pig) : TFRC (transferrin receptor)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm38 Ensembl1632,608,920 - 32,632,794 (+)Ensembl
GRCm381632,608,896 - 32,632,794 (+)NCBIGRCm38GRCm38mm10GRCm38
MGSCv371632,608,982 - 32,632,880 (+)NCBIGRCm37mm9NCBIm37
MGSCv361632,528,768 - 32,552,537 (+)NCBImm8
Celera1633,088,313 - 33,112,331 (+)NCBICelera
Cytogenetic Map16 B3NCBI
cM Map1623.06NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Tfrc
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 70503
Created: 2002-05-02
Species: Mus musculus
Last Modified: 2020-01-07
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.