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Gene: Mlh1 (mutL homolog 1) Mus musculus
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Symbol: Mlh1
Name: mutL homolog 1
Description: ENCODES a protein that exhibits chromatin binding; guanine/thymine mispair binding; enzyme binding (ortholog); INVOLVED IN cellular response to DNA damage stimulus; DNA repair; double-strand break repair via nonhomologous end joining; PARTICIPATES IN altered mismatch repair pathway; colorectal cancer pathway; endometrial cancer pathway; ASSOCIATED WITH abnormal apoptosis; abnormal chiasmata formation; abnormal chromosomal synapsis; ASSOCIATED WITH cervix uteri carcinoma in situ (ortholog); colon cancer (ortholog); colon carcinoma (ortholog); FOUND IN chiasma; chromosome; condensed chromosome; INTERACTS WITH 1,2-dimethylhydrazine; 2,3,7,8-tetrachlorodibenzodioxine; 2,3,7,8-Tetrachlorodibenzofuran
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 1110035C23Rik; AI317206; AI325952; AI561766; colon cancer, nonpolyposis type 2; DNA mismatch repair protein Mlh1; mutL protein homolog 1
Orthologs:
Homo sapiens (human) : MLH1 (mutL homolog 1)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Mlh1 (mutL homolog 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Mlh1 (mutL homolog 1)
Pan paniscus (bonobo/pygmy chimpanzee) : MLH1 (mutL homolog 1)
Canis lupus familiaris (dog) : MLH1 (mutL homolog 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Mlh1 (mutL homolog 1)
Sus scrofa (pig) : MLH1 (mutL homolog 1)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm389111,228,228 - 111,271,786 (-)NCBIGRCm38GRCm38mm10GRCm38
MGSCv379111,130,732 - 111,174,112 (-)NCBIGRCm37mm9NCBIm37
MGSCv369111,073,071 - 111,116,378 (-)NCBImm8
Celera9110,951,307 - 110,994,774 (-)NCBICelera
Cytogenetic Map9 F3NCBI
cM Map960.92NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)