(+)-pilocarpine multiple interactions EXP 6480464 Pilocarpine promotes the reaction [EIF2AK3 protein modified form results in increased phosphorylation of EIF2S1 protein] CTD PMID:16492139 (+)-pilocarpine increases activity EXP 6480464 Pilocarpine results in increased activity of EIF2AK3 protein CTD PMID:16492139 (S)-nicotine multiple interactions ISO RGD:70884 6480464 Mecamylamine inhibits the reaction [Nicotine results in increased phosphorylation of EIF2AK3 protein], ursodoxicoltaurine inhibits the reaction [Nicotine results in increased phosphorylation of EIF2AK3 protein] CTD PMID:26803847 (S)-nicotine increases phosphorylation ISO RGD:70884 6480464 Nicotine results in increased phosphorylation of EIF2AK3 protein CTD PMID:26803847 1,2,4-trimethylbenzene decreases expression ISO RGD:70884 6480464 pseudocumene results in decreased expression of EIF2AK3 protein CTD PMID:17337753 1,2-dichloroethane increases expression EXP 6480464 ethylene dichloride results in increased expression of EIF2AK3 mRNA CTD PMID:28973639 1,2-dimethylhydrazine decreases phosphorylation ISO RGD:70884 6480464 1, 2-Dimethylhydrazine results in decreased phosphorylation of EIF2AK3 protein CTD PMID:29879413 1,2-dimethylhydrazine decreases expression EXP 6480464 1, 2-Dimethylhydrazine results in decreased expression of EIF2AK3 mRNA CTD PMID:22206623 1,2-dimethylhydrazine multiple interactions ISO RGD:70884 6480464 trans-3-4'-hydroxyphenyl-2-propenoic acid inhibits the reaction [1, 2-Dimethylhydrazine results in decreased phosphorylation of EIF2AK3 protein] CTD PMID:29879413 1,4-dithiothreitol multiple interactions ISO RGD:70884 6480464 Dithiothreitol results in increased phosphorylation of and results in increased activity of EIF2AK3 protein CTD PMID:12486162 1,4-dithiothreitol increases phosphorylation ISO RGD:1354090 6480464 Dithiothreitol results in increased phosphorylation of EIF2AK3 protein CTD PMID:25321315 17beta-estradiol increases expression ISO RGD:1354090 6480464 Estradiol results in increased expression of EIF2AK3 mRNA CTD PMID:20106945 17beta-estradiol decreases expression ISO RGD:1354090 6480464 Estradiol results in decreased expression of EIF2AK3 mRNA CTD PMID:19167446 17beta-hydroxy-5alpha-androstan-3-one increases expression ISO RGD:1354090 6480464 Dihydrotestosterone results in increased expression of EIF2AK3 mRNA CTD PMID:29581250 2,2',4,4'-Tetrabromodiphenyl ether increases expression ISO RGD:1354090 6480464 2 more ... CTD PMID:19095052 2,2',4,4'-Tetrabromodiphenyl ether affects expression EXP 6480464 2 more ... CTD PMID:30294300 2,2',4,4'-Tetrabromodiphenyl ether multiple interactions EXP 6480464 epoxomicin inhibits the reaction [troxerutin inhibits the reaction [2 more ... CTD PMID:25639565 2,2',4,4'-Tetrabromodiphenyl ether increases phosphorylation EXP 6480464 2 more ... CTD PMID:25639565 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of EIF2AK3 mRNA CTD PMID:19770486 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:70884 6480464 Tetrachlorodibenzodioxin results in increased expression of EIF2AK3 mRNA CTD PMID:32109520 2,3,7,8-tetrachlorodibenzodioxine multiple interactions EXP 6480464 [TIPARP gene mutant form results in increased susceptibility to Tetrachlorodibenzodioxin] which results in decreased expression of EIF2AK3 mRNA CTD PMID:25975270 2,3,7,8-tetrachlorodibenzodioxine increases phosphorylation ISO RGD:70884 6480464 Tetrachlorodibenzodioxin results in increased phosphorylation of EIF2AK3 protein CTD PMID:24932542 2,3-dimethoxynaphthalene-1,4-dione increases phosphorylation ISO RGD:1354090 6480464 2 more ... CTD PMID:21703327 2-amino-2-deoxy-D-glucopyranose multiple interactions ISO RGD:70884 6480464 EIF2AK3 gene mutant form inhibits the reaction [Glucosamine results in increased phosphorylation of EIF2S1 protein] CTD PMID:16324875 2-amino-2-deoxy-D-glucopyranose multiple interactions EXP 6480464 EIF2AK3 protein affects the reaction [Glucosamine results in increased expression of ATF4 mRNA] more ... CTD PMID:30602124 2-amino-2-deoxy-D-glucopyranose increases phosphorylation ISO RGD:1354090 6480464 Glucosamine results in increased phosphorylation of EIF2AK3 protein CTD PMID:19383982 2-hydroxypropanoic acid increases expression ISO RGD:1354090 6480464 Lactic Acid results in increased expression of EIF2AK3 mRNA CTD PMID:30851411 2-methyl-6-(phenylethynyl)pyridine multiple interactions ISO RGD:70884 6480464 6-methyl-2-phenylethynylpyridine inhibits the reaction [Cocaine results in increased expression of EIF2AK3 protein] CTD PMID:17303341 2-tert-butylhydroquinone multiple interactions ISO RGD:1354090 6480464 2-tert-butylhydroquinone inhibits the reaction [pterostilbene results in increased phosphorylation of EIF2AK3 protein] CTD PMID:25341683 3H-1,2-dithiole-3-thione multiple interactions EXP 6480464 1 more ... CTD PMID:22959925 3H-1,2-dithiole-3-thione decreases expression ISO RGD:70884 6480464 1, 2-dithiol-3-thione results in decreased expression of EIF2AK3 mRNA CTD PMID:19162173 4,4'-diisothiocyano-trans-stilbene-2,2'-disulfonic acid multiple interactions EXP 6480464 4 more ... CTD PMID:27638049 4-hydroxynon-2-enal increases phosphorylation EXP 6480464 4-hydroxy-2-nonenal results in increased phosphorylation of EIF2AK3 protein CTD PMID:19041636 4-hydroxyphenyl retinamide multiple interactions ISO RGD:1354090 6480464 EIF2AK3 mutant form inhibits the reaction [Fenretinide results in increased phosphorylation of EIF2S1 protein] CTD PMID:20022965 4-hydroxyphenyl retinamide decreases response to substance ISO RGD:1354090 6480464 EIF2AK3 results in decreased susceptibility to Fenretinide CTD PMID:20022965 4-phenylbutyric acid decreases expression ISO RGD:70884 6480464 4-phenylbutyric acid results in decreased expression of EIF2AK3 protein modified form CTD PMID:27484784 4-phenylbutyric acid decreases expression ISO RGD:1354090 6480464 4-phenylbutyric acid results in decreased expression of EIF2AK3 protein CTD PMID:30796460 4-phenylbutyric acid multiple interactions ISO RGD:1354090 6480464 4-phenylbutyric acid inhibits the reaction [Cadmium Chloride results in increased expression of EIF2AK3 protein] more ... CTD PMID:27470132 more ... 4-phenylbutyric acid multiple interactions ISO RGD:70884 6480464 4-phenylbutyric acid inhibits the reaction [6-chloro-2 more ... CTD PMID:27484784 more ... 5-fluorouracil increases phosphorylation ISO RGD:1354090 6480464 Fluorouracil results in increased phosphorylation of EIF2AK3 protein CTD PMID:29879413 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide increases phosphorylation ISO RGD:70884 6480464 6-chloro-2 more ... CTD PMID:29653943 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide multiple interactions ISO RGD:70884 6480464 4-phenylbutyric acid inhibits the reaction [6-chloro-2 more ... CTD PMID:29653943 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide increases acetylation ISO RGD:70884 6480464 6-chloro-2 more ... CTD PMID:29653943 acrolein increases phosphorylation EXP 6480464 Acrolein results in increased phosphorylation of EIF2AK3 protein CTD PMID:19041636 acrylamide decreases expression ISO RGD:70884 6480464 Acrylamide results in decreased expression of EIF2AK3 mRNA CTD PMID:28959563 aflatoxin B1 increases methylation ISO RGD:1354090 6480464 Aflatoxin B1 results in increased methylation of EIF2AK3 intron CTD PMID:30157460 aldehydo-D-glucosamine multiple interactions ISO RGD:70884 6480464 EIF2AK3 gene mutant form inhibits the reaction [Glucosamine results in increased phosphorylation of EIF2S1 protein] CTD PMID:16324875 aldehydo-D-glucosamine multiple interactions EXP 6480464 EIF2AK3 protein affects the reaction [Glucosamine results in increased expression of ATF4 mRNA] more ... CTD PMID:30602124 aldehydo-D-glucosamine increases phosphorylation ISO RGD:1354090 6480464 Glucosamine results in increased phosphorylation of EIF2AK3 protein CTD PMID:19383982 aldehydo-D-glucose increases phosphorylation ISO RGD:1354090 6480464 Glucose deficiency results in increased phosphorylation of EIF2AK3 protein CTD PMID:31022492 aldehydo-D-glucose multiple interactions ISO RGD:1354090 6480464 4-Quinolones analog inhibits the reaction [Glucose deficiency results in increased phosphorylation of EIF2AK3 protein] CTD PMID:31022492 all-trans-retinoic acid increases expression EXP 6480464 Tretinoin results in increased expression of EIF2AK3 mRNA, Tretinoin results in increased expression of EIF2AK3 protein CTD PMID:22498432 amiodarone increases expression ISO RGD:1354090 6480464 Amiodarone results in increased expression of EIF2AK3 mRNA CTD PMID:19774075 ammonium chloride affects expression ISO RGD:70884 6480464 Ammonium Chloride affects the expression of EIF2AK3 mRNA CTD PMID:16483693 apocynin multiple interactions ISO RGD:70884 6480464 acetovanillone inhibits the reaction [Oxygen deficiency results in increased expression of EIF2AK3 mRNA], acetovanillone inhibits the reaction [Oxygen deficiency results in increased expression of EIF2AK3 protein] CTD PMID:23270704 arsane affects methylation ISO RGD:1354090 6480464 Arsenic affects the methylation of EIF2AK3 gene CTD PMID:25304211 arsenic atom affects methylation ISO RGD:1354090 6480464 Arsenic affects the methylation of EIF2AK3 gene CTD PMID:25304211 arsenous acid increases phosphorylation ISO RGD:70884 6480464 Arsenic Trioxide results in increased phosphorylation of EIF2AK3 protein CTD PMID:29111283 arsenous acid multiple interactions EXP 6480464 2-4-chlorophenoxy-N-4-2-4-chlorophenoxyacetamidocyclohexylacetamide inhibits the reaction [Arsenic Trioxide results in increased expression of EIF2AK3 protein modified form] more ... CTD PMID:27638049 arsenous acid increases expression EXP 6480464 Arsenic Trioxide results in increased expression of EIF2AK3 protein modified form CTD PMID:27638049 arsenous acid increases phosphorylation EXP 6480464 Arsenic Trioxide results in increased phosphorylation of EIF2AK3 protein CTD PMID:29111283 arsenous acid increases expression ISO RGD:1354090 6480464 Arsenic Trioxide results in increased expression of EIF2AK3 mRNA, Arsenic Trioxide results in increased expression of EIF2AK3 protein modified form CTD PMID:17963750 , PMID:22922937 arsenous acid multiple interactions ISO RGD:1354090 6480464 sulforafan promotes the reaction [Arsenic Trioxide results in increased expression of EIF2AK3 protein modified form] CTD PMID:22922937 atorvastatin calcium multiple interactions ISO RGD:1354090 6480464 EIF2AK3 mutant form inhibits the reaction [Atorvastatin results in increased phosphorylation of EIF2S1 protein] CTD PMID:20876807 atorvastatin calcium increases response to substance ISO RGD:1354090 6480464 EIF2AK3 results in increased susceptibility to Atorvastatin CTD PMID:20876807 Aurin increases phosphorylation ISO RGD:1354090 6480464 aurin results in increased phosphorylation of EIF2AK3 protein CTD PMID:25477506 Azaspiracid increases expression ISO RGD:1354090 6480464 azaspiracid results in increased expression of EIF2AK3 mRNA CTD PMID:28939011 BAPTA multiple interactions ISO RGD:1354090 6480464 [fisetin co-treated with 1 more ... CTD PMID:28181380 BAPTA increases expression ISO RGD:1354090 6480464 1 more ... CTD PMID:28181380 benomyl multiple interactions ISO RGD:1354090 6480464 Acetylcysteine inhibits the reaction [Benomyl results in increased expression of EIF2AK3 protein], MitoTEMPO inhibits the reaction [Benomyl results in increased expression of EIF2AK3 protein] CTD PMID:27784618 benomyl increases expression ISO RGD:1354090 6480464 Benomyl results in increased expression of EIF2AK3 protein CTD PMID:27784618 benzo[a]pyrene increases methylation EXP 6480464 Benzoapyrene results in increased methylation of EIF2AK3 exon, Benzoapyrene results in increased methylation of EIF2AK3 intron CTD PMID:27901495 benzo[a]pyrene diol epoxide I affects expression ISO RGD:1354090 6480464 7 more ... CTD PMID:20382639 beta-D-glucosamine multiple interactions ISO RGD:70884 6480464 EIF2AK3 gene mutant form inhibits the reaction [Glucosamine results in increased phosphorylation of EIF2S1 protein] CTD PMID:16324875 beta-D-glucosamine multiple interactions EXP 6480464 EIF2AK3 protein affects the reaction [Glucosamine results in increased expression of ATF4 mRNA] more ... CTD PMID:30602124 beta-D-glucosamine increases phosphorylation ISO RGD:1354090 6480464 Glucosamine results in increased phosphorylation of EIF2AK3 protein CTD PMID:19383982 bilirubin IXalpha multiple interactions ISO RGD:1354090 6480464 Bilirubin results in increased phosphorylation of and results in increased activity of EIF2AK3 protein, EIF2AK3 mRNA promotes the reaction [Bilirubin results in increased expression of CXCL8 mRNA] CTD PMID:20196124 , PMID:27578021 bis(2-chloroethyl) sulfide increases expression EXP 6480464 Mustard Gas results in increased expression of EIF2AK3 mRNA CTD PMID:15674844 bisphenol A affects expression ISO RGD:1354090 6480464 bisphenol A affects the expression of EIF2AK3 mRNA CTD PMID:22574217 bisphenol A increases expression ISO RGD:70884 6480464 bisphenol A results in increased expression of EIF2AK3 mRNA CTD PMID:18180321 more ... bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of EIF2AK3 mRNA CTD PMID:26063408 boric acid multiple interactions EXP 6480464 EIF2AK3 protein affects the reaction [boric acid affects the localization of NFE2L2 protein] more ... CTD PMID:30196486 bortezomib increases phosphorylation ISO RGD:1354090 6480464 Bortezomib results in increased phosphorylation of EIF2AK3 protein CTD PMID:15509775 , PMID:16928686 bortezomib increases phosphorylation EXP 6480464 Bortezomib results in increased phosphorylation of EIF2AK3 protein CTD PMID:15509775 bortezomib multiple interactions EXP 6480464 Bortezomib inhibits the reaction [1, 2-dithiol-3-thione inhibits the reaction [Tunicamycin results in increased expression of EIF2AK3 mRNA]] CTD PMID:22959925 bortezomib multiple interactions ISO RGD:1354090 6480464 EIF2AK3 mutant form inhibits the reaction [Bortezomib results in increased phosphorylation of EIF2S1 protein] CTD PMID:20022965 bortezomib decreases response to substance ISO RGD:1354090 6480464 EIF2AK3 results in decreased susceptibility to Bortezomib CTD PMID:20022965 brefeldin A increases expression ISO RGD:1354090 6480464 Brefeldin A results in increased expression of EIF2AK3 protein CTD PMID:24865413 bufalin decreases phosphorylation ISO RGD:1354090 6480464 bufalin results in decreased phosphorylation of EIF2AK3 protein CTD PMID:23949904 cadmium atom increases phosphorylation ISO RGD:1354090 6480464 Cadmium results in increased phosphorylation of EIF2AK3 protein CTD PMID:20600546 cadmium atom decreases phosphorylation ISO RGD:70884 6480464 Cadmium results in decreased phosphorylation of EIF2AK3 protein CTD PMID:27658547 cadmium dichloride increases expression EXP 6480464 Cadmium Chloride results in increased expression of EIF2AK3 protein modified form CTD PMID:21325019 cadmium dichloride multiple interactions ISO RGD:1354090 6480464 4-phenylbutyric acid inhibits the reaction [Cadmium Chloride results in increased expression of EIF2AK3 protein] CTD PMID:30796460 cadmium dichloride increases expression ISO RGD:1354090 6480464 Cadmium Chloride results in increased expression of EIF2AK3 protein CTD PMID:30796460 calcium atom multiple interactions ISO RGD:1354090 6480464 Calcium promotes the reaction [Diclofenac results in increased phosphorylation of EIF2AK3 protein] CTD PMID:26609140 calcium(0) multiple interactions ISO RGD:1354090 6480464 Calcium promotes the reaction [Diclofenac results in increased phosphorylation of EIF2AK3 protein] CTD PMID:26609140 camptothecin increases phosphorylation ISO RGD:1354090 6480464 Camptothecin results in increased phosphorylation of EIF2AK3 protein CTD PMID:30266318 camptothecin multiple interactions ISO RGD:1354090 6480464 Glutathione inhibits the reaction [Camptothecin results in increased phosphorylation of EIF2AK3 protein], MYC protein affects the reaction [Camptothecin results in increased phosphorylation of EIF2AK3 protein] CTD PMID:30266318 cannabidiol decreases expression EXP 6480464 Cannabidiol results in decreased expression of EIF2AK3 mRNA CTD PMID:33019509 cannabigerol decreases expression EXP 6480464 cannabigerol results in decreased expression of EIF2AK3 mRNA CTD PMID:33019509 cantharidin increases expression ISO RGD:1354090 6480464 Cantharidin results in increased expression of EIF2AK3 protein CTD PMID:27113412 carbamazepine increases activity ISO RGD:1354090 6480464 Carbamazepine results in increased activity of EIF2AK3 protein CTD PMID:24752500 carbamazepine affects expression ISO RGD:1354090 6480464 Carbamazepine affects the expression of EIF2AK3 mRNA CTD PMID:24752500 chloroacetic acid multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [chloroacetic acid results in increased phosphorylation of EIF2AK3 protein] CTD PMID:25451595 chloroacetic acid increases phosphorylation EXP 6480464 chloroacetic acid results in increased phosphorylation of EIF2AK3 protein CTD PMID:25451595 choline multiple interactions EXP 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of EIF2AK3 gene CTD PMID:20938992 chromium(6+) increases phosphorylation ISO RGD:1354090 6480464 chromium hexavalent ion results in increased phosphorylation of EIF2AK3 protein CTD PMID:30416085 chrysophanol multiple interactions ISO RGD:1354090 6480464 Acetylcysteine inhibits the reaction [chrysophanic acid results in increased phosphorylation of EIF2AK3 protein] CTD PMID:30300626 chrysophanol increases phosphorylation ISO RGD:1354090 6480464 chrysophanic acid results in increased phosphorylation of EIF2AK3 protein CTD PMID:30300626 ciglitazone multiple interactions ISO RGD:1354090 6480464 ciglitazone promotes the reaction [Niflumic Acid results in increased phosphorylation of EIF2AK3 protein], Niflumic Acid promotes the reaction [ciglitazone results in increased phosphorylation of EIF2AK3 protein] CTD PMID:21067863 ciglitazone increases phosphorylation ISO RGD:1354090 6480464 ciglitazone results in increased phosphorylation of EIF2AK3 protein CTD PMID:21067863 cisplatin multiple interactions ISO RGD:1354090 6480464 [Cisplatin results in decreased susceptibility to Cisplatin] which results in increased expression of EIF2AK3 mRNA CTD PMID:30871063 clofibric acid affects expression ISO RGD:70884 6480464 Clofibric Acid affects the expression of EIF2AK3 mRNA CTD PMID:17602206 cocaine increases expression ISO RGD:70884 6480464 Cocaine results in increased expression of EIF2AK3 protein CTD PMID:17303341 cocaine multiple interactions ISO RGD:70884 6480464 6-methyl-2-phenylethynylpyridine inhibits the reaction [Cocaine results in increased expression of EIF2AK3 protein] more ... CTD PMID:17303341 copper atom multiple interactions ISO RGD:1354090 6480464 [Chelating Agents binds to Copper] which affects the expression of EIF2AK3 mRNA CTD PMID:30911355 copper(0) multiple interactions ISO RGD:1354090 6480464 [Chelating Agents binds to Copper] which affects the expression of EIF2AK3 mRNA CTD PMID:30911355 copper(II) sulfate decreases expression ISO RGD:1354090 6480464 Copper Sulfate results in decreased expression of EIF2AK3 mRNA CTD PMID:19549813 coumestrol decreases expression ISO RGD:1354090 6480464 Coumestrol results in decreased expression of EIF2AK3 mRNA CTD PMID:19167446 cycloheximide multiple interactions ISO RGD:70884 6480464 Cycloheximide inhibits the reaction [dimethylarsinous acid results in increased phosphorylation of EIF2AK3 protein] CTD PMID:22425709 cyclophosphamide increases phosphorylation ISO RGD:70884 6480464 Cyclophosphamide results in increased phosphorylation of EIF2AK3 protein CTD PMID:32197949 cyclophosphamide multiple interactions ISO RGD:70884 6480464 sacubitril-valsartan inhibits the reaction [Cyclophosphamide results in increased phosphorylation of EIF2AK3 protein], Valsartan inhibits the reaction [Cyclophosphamide results in increased phosphorylation of EIF2AK3 protein] CTD PMID:32197949 cyclosporin A increases expression ISO RGD:1354090 6480464 Cyclosporine results in increased expression of EIF2AK3 mRNA CTD PMID:20106945 more ... cyproconazole multiple interactions ISO RGD:70884 6480464 [cyproconazole co-treated with epoxiconazole co-treated with prochloraz] results in increased expression of EIF2AK3 mRNA CTD PMID:29038839 D-glucose multiple interactions ISO RGD:1354090 6480464 4-Quinolones analog inhibits the reaction [Glucose deficiency results in increased phosphorylation of EIF2AK3 protein] CTD PMID:31022492 D-glucose increases phosphorylation ISO RGD:1354090 6480464 Glucose deficiency results in increased phosphorylation of EIF2AK3 protein CTD PMID:31022492 D-penicillamine multiple interactions ISO RGD:1354090 6480464 Penicillamine results in increased phosphorylation of and results in increased activity of EIF2AK3 protein CTD PMID:22843330 dantrolene decreases phosphorylation ISO RGD:70884 6480464 Dantrolene results in decreased phosphorylation of EIF2AK3 protein CTD PMID:15921666 Deguelin increases phosphorylation ISO RGD:1354090 6480464 deguelin results in increased phosphorylation of EIF2AK3 protein CTD PMID:25322282 demethoxycurcumin multiple interactions ISO RGD:1354090 6480464 demethoxycurcumin analog inhibits the reaction [Thapsigargin results in increased phosphorylation of EIF2AK3 protein] CTD PMID:26264395 diarsenic trioxide increases phosphorylation EXP 6480464 Arsenic Trioxide results in increased phosphorylation of EIF2AK3 protein CTD PMID:29111283 diarsenic trioxide increases expression EXP 6480464 Arsenic Trioxide results in increased expression of EIF2AK3 protein modified form CTD PMID:27638049 diarsenic trioxide multiple interactions ISO RGD:1354090 6480464 sulforafan promotes the reaction [Arsenic Trioxide results in increased expression of EIF2AK3 protein modified form] CTD PMID:22922937 diarsenic trioxide increases expression ISO RGD:1354090 6480464 Arsenic Trioxide results in increased expression of EIF2AK3 mRNA, Arsenic Trioxide results in increased expression of EIF2AK3 protein modified form CTD PMID:17963750 , PMID:22922937 diarsenic trioxide multiple interactions EXP 6480464 2-4-chlorophenoxy-N-4-2-4-chlorophenoxyacetamidocyclohexylacetamide inhibits the reaction [Arsenic Trioxide results in increased expression of EIF2AK3 protein modified form] more ... CTD PMID:27638049 diarsenic trioxide increases phosphorylation ISO RGD:70884 6480464 Arsenic Trioxide results in increased phosphorylation of EIF2AK3 protein CTD PMID:29111283 dibutyl phthalate increases expression EXP 6480464 Dibutyl Phthalate results in increased expression of EIF2AK3 mRNA CTD PMID:21266533 dibutyl phthalate multiple interactions EXP 6480464 7-methyl-5-1-3-trifluoromethylphenylacetyl-2 more ... CTD PMID:30910607 dibutyl phthalate increases phosphorylation ISO RGD:70884 6480464 Dibutyl Phthalate results in increased phosphorylation of EIF2AK3 protein CTD PMID:30910607 dibutyl phthalate increases phosphorylation EXP 6480464 Dibutyl Phthalate results in increased phosphorylation of EIF2AK3 protein CTD PMID:30910607 diclofenac increases phosphorylation ISO RGD:1354090 6480464 Diclofenac results in increased phosphorylation of EIF2AK3 protein CTD PMID:26609140 diclofenac increases expression EXP 6480464 Diclofenac results in increased expression of EIF2AK3 mRNA CTD PMID:26934552 diclofenac increases activity ISO RGD:1354090 6480464 Diclofenac results in increased activity of EIF2AK3 protein CTD PMID:24752500 diclofenac affects expression ISO RGD:1354090 6480464 Diclofenac affects the expression of EIF2AK3 mRNA CTD PMID:24752500 diclofenac multiple interactions ISO RGD:1354090 6480464 1 more ... CTD PMID:26609140 dimethylarsinous acid multiple interactions ISO RGD:70884 6480464 Cycloheximide inhibits the reaction [dimethylarsinous acid results in increased phosphorylation of EIF2AK3 protein] CTD PMID:22425709 dimethylarsinous acid increases phosphorylation ISO RGD:70884 6480464 dimethylarsinous acid results in increased phosphorylation of EIF2AK3 protein CTD PMID:22425709 dioxygen increases phosphorylation EXP 6480464 Oxygen deficiency results in increased phosphorylation of EIF2AK3 protein CTD PMID:19041636 dioxygen increases expression ISO RGD:70884 6480464 Oxygen deficiency results in increased expression of EIF2AK3 mRNA, Oxygen deficiency results in increased expression of EIF2AK3 protein CTD PMID:22226148 , PMID:23270704 dioxygen multiple interactions ISO RGD:70884 6480464 4-chlorobenzyltetrahydroberberine inhibits the reaction [Oxygen deficiency results in increased expression of EIF2AK3 mRNA] more ... CTD PMID:19041636 more ... dorsomorphin multiple interactions ISO RGD:1354090 6480464 [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-5-benzo1, 3dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-ylbenzamide] results in increased expression of EIF2AK3 mRNA CTD PMID:27188386 doxorubicin multiple interactions EXP 6480464 Doxorubicin results in increased phosphorylation of and results in increased activity of EIF2AK3 protein CTD PMID:20656019 efavirenz increases expression ISO RGD:1354090 6480464 efavirenz results in increased expression of EIF2AK3 protein modified form CTD PMID:28940366 endosulfan decreases expression ISO RGD:70884 6480464 Endosulfan results in decreased expression of EIF2AK3 mRNA CTD PMID:29391264 epoxiconazole increases expression ISO RGD:70884 6480464 epoxiconazole results in increased expression of EIF2AK3 mRNA CTD PMID:29038839 epoxiconazole multiple interactions ISO RGD:70884 6480464 [cyproconazole co-treated with epoxiconazole co-treated with prochloraz] results in increased expression of EIF2AK3 mRNA CTD PMID:29038839 epoxomicin multiple interactions EXP 6480464 epoxomicin inhibits the reaction [troxerutin inhibits the reaction [2 more ... CTD PMID:25639565 ethanol increases phosphorylation ISO RGD:70884 6480464 Ethanol results in increased phosphorylation of EIF2AK3 protein CTD PMID:26747958 ethanol increases expression ISO RGD:1354090 6480464 Ethanol results in increased expression of EIF2AK3 protein modified form CTD PMID:24224909 ethanol multiple interactions ISO RGD:1354090 6480464 resveratrol inhibits the reaction [Ethanol results in increased expression of EIF2AK3 protein modified form] CTD PMID:24224909 ethanol increases phosphorylation EXP 6480464 Ethanol results in increased phosphorylation of EIF2AK3 protein CTD PMID:28119953 ethanol multiple interactions ISO RGD:70884 6480464 [[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] co-treated with Ethanol] results in increased phosphorylation of EIF2AK3 protein more ... CTD PMID:26747958 fisetin multiple interactions ISO RGD:1354090 6480464 [fisetin co-treated with 1 more ... CTD PMID:28181380 flavokawain B increases phosphorylation ISO RGD:1354090 6480464 flavokawain B results in increased phosphorylation of EIF2AK3 protein CTD PMID:30025493 fluoranthene multiple interactions EXP 6480464 [1-methylanthracene co-treated with fluoranthene] results in increased expression of EIF2AK3 mRNA CTD PMID:28329830 folic acid multiple interactions EXP 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of EIF2AK3 gene CTD PMID:20938992 formaldehyde decreases expression ISO RGD:1354090 6480464 Formaldehyde results in decreased expression of EIF2AK3 mRNA CTD PMID:20655997 formaldehyde increases phosphorylation ISO RGD:1354090 6480464 Formaldehyde results in increased phosphorylation of EIF2AK3 protein CTD PMID:24140967 fructose increases phosphorylation EXP 6480464 Fructose results in increased phosphorylation of EIF2AK3 protein CTD PMID:22698815 fructose multiple interactions EXP 6480464 Phenylbutyrates inhibits the reaction [Fructose results in increased phosphorylation of EIF2AK3 protein] CTD PMID:22698815 gadolinium trichloride increases expression ISO RGD:70884 6480464 gadolinium chloride results in increased expression of EIF2AK3 protein CTD PMID:21198628 geraniol multiple interactions ISO RGD:1354090 6480464 geraniol inhibits the reaction [Rotenone results in increased expression of EIF2AK3 protein] CTD PMID:30141137 glucose increases phosphorylation ISO RGD:1354090 6480464 Glucose deficiency results in increased phosphorylation of EIF2AK3 protein CTD PMID:31022492 glucose multiple interactions ISO RGD:1354090 6480464 4-Quinolones analog inhibits the reaction [Glucose deficiency results in increased phosphorylation of EIF2AK3 protein] CTD PMID:31022492 glutathione multiple interactions ISO RGD:1354090 6480464 Glutathione inhibits the reaction [Camptothecin results in increased phosphorylation of EIF2AK3 protein], Glutathione inhibits the reaction [NR4A1 protein affects the phosphorylation of EIF2AK3 protein] CTD PMID:24515801 , PMID:30266318 gold atom increases phosphorylation ISO RGD:1354090 6480464 Gold analog results in increased phosphorylation of EIF2AK3 protein CTD PMID:26551149 gold(0) increases phosphorylation ISO RGD:1354090 6480464 Gold analog results in increased phosphorylation of EIF2AK3 protein CTD PMID:26551149 hemin multiple interactions ISO RGD:70884 6480464 Hemin inhibits the reaction [[[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] co-treated with Ethanol] results in increased phosphorylation of EIF2AK3 protein], Hemin inhibits the reaction [[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] results in increased phosphorylation of EIF2AK3 protein] CTD PMID:26747958 hexadecanoic acid multiple interactions ISO RGD:1354090 6480464 3-N-1spermine-7 more ... CTD PMID:30547786 , PMID:32369900 homocysteine decreases phosphorylation ISO RGD:1354090 6480464 Homocysteine results in decreased phosphorylation of EIF2AK3 protein CTD PMID:22964297 hydrogen peroxide affects expression ISO RGD:1354090 6480464 Hydrogen Peroxide affects the expression of EIF2AK3 mRNA CTD PMID:20044591 isoprenaline increases expression EXP 6480464 Isoproterenol results in increased expression of EIF2AK3 mRNA CTD PMID:21335049 ketoconazole multiple interactions EXP 6480464 Ketoconazole inhibits the reaction [Tunicamycin results in increased phosphorylation of EIF2AK3 protein] CTD PMID:16330322 L-1,4-dithiothreitol multiple interactions ISO RGD:70884 6480464 Dithiothreitol results in increased phosphorylation of and results in increased activity of EIF2AK3 protein CTD PMID:12486162 L-1,4-dithiothreitol increases phosphorylation ISO RGD:1354090 6480464 Dithiothreitol results in increased phosphorylation of EIF2AK3 protein CTD PMID:25321315 L-methionine multiple interactions EXP 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased methylation of EIF2AK3 gene CTD PMID:20938992 lead diacetate increases phosphorylation ISO RGD:70884 6480464 lead acetate results in increased phosphorylation of EIF2AK3 protein CTD PMID:25088297 lead diacetate multiple interactions ISO RGD:70884 6480464 Proanthocyanidins inhibits the reaction [lead acetate results in increased phosphorylation of EIF2AK3 protein] CTD PMID:25088297 linsidomine increases phosphorylation ISO RGD:1354090 6480464 linsidomine results in increased phosphorylation of EIF2AK3 protein CTD PMID:21703327 lipopolysaccharide increases phosphorylation ISO RGD:1354090 6480464 Lipopolysaccharides results in increased phosphorylation of EIF2AK3 protein CTD PMID:19675143 , PMID:28245985 lipopolysaccharide multiple interactions EXP 6480464 salvianolic acid A inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of EIF2AK3 protein] CTD PMID:31654708 lipopolysaccharide increases phosphorylation EXP 6480464 Lipopolysaccharides results in increased phosphorylation of EIF2AK3 protein CTD PMID:31654708 lipopolysaccharide multiple interactions ISO RGD:1354090 6480464 4-phenylbutyric acid inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of EIF2AK3 protein] CTD PMID:28245985 lycopene multiple interactions ISO RGD:70884 6480464 Lycopene inhibits the reaction [Oxaliplatin results in increased expression of EIF2AK3 mRNA] CTD PMID:32544411 manganese atom multiple interactions ISO RGD:70884 6480464 [manganese chloride results in increased abundance of Manganese] which results in increased phosphorylation of EIF2AK3 protein CTD PMID:32574669 manganese(0) multiple interactions ISO RGD:70884 6480464 [manganese chloride results in increased abundance of Manganese] which results in increased phosphorylation of EIF2AK3 protein CTD PMID:32574669 manganese(II) chloride increases phosphorylation ISO RGD:70884 6480464 manganese chloride results in increased phosphorylation of EIF2AK3 protein CTD PMID:23948121 manganese(II) chloride increases expression ISO RGD:70884 6480464 manganese chloride results in increased expression of EIF2AK3 protein CTD PMID:25732873 manganese(II) chloride multiple interactions ISO RGD:70884 6480464 [manganese chloride results in increased abundance of Manganese] which results in increased phosphorylation of EIF2AK3 protein more ... CTD PMID:23934647 more ... Mecamylamine multiple interactions ISO RGD:70884 6480464 Mecamylamine inhibits the reaction [Nicotine results in increased phosphorylation of EIF2AK3 protein] CTD PMID:26803847 meglumine amidotrizoate increases phosphorylation ISO RGD:70884 6480464 Diatrizoate Meglumine results in increased phosphorylation of EIF2AK3 protein CTD PMID:20071420 melatonin multiple interactions ISO RGD:70884 6480464 Melatonin inhibits the reaction [Methamphetamine results in increased expression of EIF2AK3 protein modified form] CTD PMID:28070110 methamphetamine multiple interactions ISO RGD:1354090 6480464 CDK5 protein affects the reaction [Methamphetamine results in increased phosphorylation of EIF2AK3 protein] more ... CTD PMID:27323860 , PMID:29705343 methamphetamine increases phosphorylation ISO RGD:70884 6480464 Methamphetamine results in increased phosphorylation of EIF2AK3 protein CTD PMID:29705343 methamphetamine multiple interactions ISO RGD:70884 6480464 CDK5 protein affects the reaction [Methamphetamine results in increased phosphorylation of EIF2AK3 protein], Melatonin inhibits the reaction [Methamphetamine results in increased expression of EIF2AK3 protein modified form] CTD PMID:28070110 , PMID:29705343 methamphetamine increases expression ISO RGD:70884 6480464 Methamphetamine results in increased expression of EIF2AK3 protein modified form CTD PMID:28070110 methamphetamine increases expression EXP 6480464 Methamphetamine results in increased expression of EIF2AK3 protein CTD PMID:27323860 methamphetamine increases phosphorylation ISO RGD:1354090 6480464 Methamphetamine results in increased phosphorylation of EIF2AK3 protein CTD PMID:27323860 , PMID:29705343 methapyrilene decreases expression ISO RGD:70884 6480464 Methapyrilene results in decreased expression of EIF2AK3 mRNA CTD PMID:30467583 methylmercury chloride increases expression ISO RGD:1354090 6480464 methylmercuric chloride results in increased expression of EIF2AK3 mRNA CTD PMID:28001369 methylmercury chloride multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [methylmercuric chloride results in increased phosphorylation of EIF2AK3 protein], AKT1 protein mutant form inhibits the reaction [methylmercuric chloride results in increased phosphorylation of EIF2AK3 protein] CTD PMID:31330229 methylmercury chloride increases phosphorylation EXP 6480464 methylmercuric chloride results in increased phosphorylation of EIF2AK3 protein CTD PMID:31330229 methylseleninic acid multiple interactions ISO RGD:1354090 6480464 HSPA5 protein inhibits the reaction [methylselenic acid results in increased phosphorylation of EIF2AK3 protein], methylselenic acid results in increased phosphorylation of and results in increased activity of EIF2AK3 protein CTD PMID:16204082 , PMID:16205645 mevastatin increases phosphorylation EXP 6480464 mevastatin results in increased phosphorylation of EIF2AK3 protein CTD PMID:16330322 minocycline increases phosphorylation ISO RGD:70884 6480464 Minocycline results in increased phosphorylation of EIF2AK3 protein CTD PMID:22245251 N,N-dimethylformamide multiple interactions ISO RGD:70884 6480464 [Dimethylformamide co-treated with Carbon Tetrachloride] results in increased expression of EIF2AK3 protein modified form CTD PMID:20097184 N-acetyl-L-cysteine multiple interactions ISO RGD:1354090 6480464 Acetylcysteine inhibits the reaction [Benomyl results in increased expression of EIF2AK3 protein] more ... CTD PMID:19722195 more ... N-acetyl-L-cysteine multiple interactions ISO RGD:70884 6480464 Acetylcysteine inhibits the reaction [tetrachlorobenzoquinone results in increased expression of EIF2AK3 protein modified form] CTD PMID:27484784 N-acetyl-L-cysteine decreases expression ISO RGD:70884 6480464 Acetylcysteine results in decreased expression of EIF2AK3 protein modified form CTD PMID:27484784 N-acetyl-L-cysteine multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [chloroacetic acid results in increased phosphorylation of EIF2AK3 protein], Acetylcysteine inhibits the reaction [methylmercuric chloride results in increased phosphorylation of EIF2AK3 protein] CTD PMID:25451595 , PMID:31330229 N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal multiple interactions EXP 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [1, 2-dithiol-3-thione inhibits the reaction [Tunicamycin results in increased expression of EIF2AK3 mRNA]] CTD PMID:22959925 N-methyl-4-phenylpyridinium multiple interactions ISO RGD:70884 6480464 1-Methyl-4-phenylpyridinium results in increased phosphorylation of and results in increased activity of EIF2AK3 protein CTD PMID:12486162 naltrexone multiple interactions ISO RGD:1354090 6480464 Naltrexone inhibits the reaction [Methamphetamine results in increased phosphorylation of EIF2AK3 protein] CTD PMID:27323860 niclosamide multiple interactions ISO RGD:1354090 6480464 ATF3 protein affects the reaction [Niclosamide results in increased expression of EIF2AK3 mRNA], Niclosamide results in increased expression of and results in increased phosphorylation of EIF2AK3 protein CTD PMID:26917416 niclosamide increases expression ISO RGD:1354090 6480464 Niclosamide results in increased expression of EIF2AK3 mRNA CTD PMID:26917416 nicotine multiple interactions ISO RGD:70884 6480464 Mecamylamine inhibits the reaction [Nicotine results in increased phosphorylation of EIF2AK3 protein], ursodoxicoltaurine inhibits the reaction [Nicotine results in increased phosphorylation of EIF2AK3 protein] CTD PMID:26803847 nicotine increases phosphorylation ISO RGD:70884 6480464 Nicotine results in increased phosphorylation of EIF2AK3 protein CTD PMID:26803847 nifedipine multiple interactions ISO RGD:70884 6480464 Nifedipine inhibits the reaction [Oxygen deficiency results in increased expression of EIF2AK3 mRNA], Nifedipine inhibits the reaction [Oxygen deficiency results in increased expression of EIF2AK3 protein] CTD PMID:22226148 Niflumic acid multiple interactions ISO RGD:1354090 6480464 ciglitazone promotes the reaction [Niflumic Acid results in increased phosphorylation of EIF2AK3 protein], Niflumic Acid promotes the reaction [ciglitazone results in increased phosphorylation of EIF2AK3 protein] CTD PMID:21067863 Niflumic acid increases phosphorylation ISO RGD:1354090 6480464 Niflumic Acid results in increased phosphorylation of EIF2AK3 protein CTD PMID:21067863 Norbinaltorphimine multiple interactions ISO RGD:1354090 6480464 norbinaltorphimine inhibits the reaction [Methamphetamine results in increased phosphorylation of EIF2AK3 protein] CTD PMID:27323860 ochratoxin A decreases expression ISO RGD:1354090 6480464 ochratoxin A results in decreased expression of EIF2AK3 mRNA CTD PMID:30763683 oleic acid multiple interactions ISO RGD:1354090 6480464 3-N-1spermine-7 more ... CTD PMID:30547786 , PMID:32369900 orlistat increases response to substance EXP 6480464 EIF2AK3 gene mutant form results in increased susceptibility to orlistat CTD PMID:17283163 orlistat multiple interactions EXP 6480464 orlistat promotes the reaction [EIF2AK3 protein results in increased phosphorylation of EIF2A protein] CTD PMID:17283163 ouabain multiple interactions ISO RGD:1354090 6480464 Ouabain results in increased expression of and results in increased phosphorylation of EIF2AK3 protein CTD PMID:31436044 oxaliplatin multiple interactions ISO RGD:70884 6480464 [Oxaliplatin co-treated with Topotecan] results in decreased expression of EIF2AK3 mRNA, Lycopene inhibits the reaction [Oxaliplatin results in increased expression of EIF2AK3 mRNA] CTD PMID:25729387 , PMID:32544411 oxaliplatin increases expression ISO RGD:70884 6480464 Oxaliplatin results in increased expression of EIF2AK3 mRNA CTD PMID:32544411 oxidopamine affects response to substance EXP 6480464 EIF2AK3 protein affects the susceptibility to Oxidopamine CTD PMID:12486162 oxidopamine multiple interactions ISO RGD:70884 6480464 Oxidopamine results in increased phosphorylation of and results in increased activity of EIF2AK3 protein CTD PMID:12486162 paclitaxel affects response to substance ISO RGD:1354090 6480464 EIF2AK3 protein affects the susceptibility to Paclitaxel CTD PMID:16217747 paracetamol affects expression EXP 6480464 Acetaminophen affects the expression of EIF2AK3 mRNA CTD PMID:17562736 paraquat increases phosphorylation ISO RGD:70884 6480464 Paraquat results in increased phosphorylation of EIF2AK3 protein CTD PMID:22245251 paraquat increases phosphorylation ISO RGD:1354090 6480464 Paraquat results in increased phosphorylation of EIF2AK3 protein CTD PMID:28986289 paraquat increases expression ISO RGD:1354090 6480464 Paraquat results in increased expression of EIF2AK3 protein modified form CTD PMID:28986289 paraquat increases expression EXP 6480464 Paraquat results in increased expression of EIF2AK3 protein modified form CTD PMID:27442881 pirinixic acid multiple interactions EXP 6480464 [pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of EIF2AK3 mRNA CTD PMID:19710929 pirinixic acid decreases expression EXP 6480464 pirinixic acid results in decreased expression of EIF2AK3 mRNA CTD PMID:17426115 platycodin D increases phosphorylation ISO RGD:1354090 6480464 platycodin D results in increased phosphorylation of EIF2AK3 protein CTD PMID:22784044 proanthocyanidin multiple interactions ISO RGD:70884 6480464 Proanthocyanidins inhibits the reaction [lead acetate results in increased phosphorylation of EIF2AK3 protein] CTD PMID:25088297 prochloraz multiple interactions ISO RGD:70884 6480464 [cyproconazole co-treated with epoxiconazole co-treated with prochloraz] results in increased expression of EIF2AK3 mRNA CTD PMID:29038839 propiconazole increases expression EXP 6480464 propiconazole results in increased expression of EIF2AK3 mRNA CTD PMID:21278054 pterostilbene increases phosphorylation ISO RGD:1354090 6480464 pterostilbene results in increased phosphorylation of EIF2AK3 protein CTD PMID:25341683 pterostilbene multiple interactions ISO RGD:1354090 6480464 2-tert-butylhydroquinone inhibits the reaction [pterostilbene results in increased phosphorylation of EIF2AK3 protein] more ... CTD PMID:25341683 pyrazinecarboxamide multiple interactions ISO RGD:1354090 6480464 4-phenylbutyric acid inhibits the reaction [Pyrazinamide results in increased phosphorylation of EIF2AK3 protein] CTD PMID:28063906 pyrazinecarboxamide increases phosphorylation ISO RGD:1354090 6480464 Pyrazinamide results in increased phosphorylation of EIF2AK3 protein CTD PMID:28063906 pyrazinecarboxamide increases phosphorylation ISO RGD:70884 6480464 Pyrazinamide results in increased phosphorylation of EIF2AK3 protein CTD PMID:28063906 pyrazinecarboxamide multiple interactions ISO RGD:70884 6480464 4-phenylbutyric acid inhibits the reaction [Pyrazinamide results in increased phosphorylation of EIF2AK3 protein] CTD PMID:28063906 quercetin increases phosphorylation ISO RGD:1354090 6480464 Quercetin results in increased phosphorylation of EIF2AK3 protein CTD PMID:24368982 , PMID:24612139 rac-lactic acid increases expression ISO RGD:1354090 6480464 Lactic Acid results in increased expression of EIF2AK3 mRNA CTD PMID:30851411 resveratrol increases phosphorylation ISO RGD:1354090 6480464 resveratrol results in increased phosphorylation of EIF2AK3 protein CTD PMID:24264887 resveratrol multiple interactions ISO RGD:1354090 6480464 resveratrol inhibits the reaction [Ethanol results in increased expression of EIF2AK3 protein modified form] CTD PMID:24224909 resveratrol multiple interactions ISO RGD:70884 6480464 [resveratrol co-treated with Dietary Fats] results in decreased phosphorylation of EIF2AK3 protein CTD PMID:26055348 resveratrol multiple interactions EXP 6480464 Resveratrol inhibits the reaction [titanium dioxide results in increased expression of EIF2AK3 mRNA] CTD PMID:31298478 rifampicin increases phosphorylation ISO RGD:70884 6480464 Rifampin results in increased phosphorylation of EIF2AK3 protein CTD PMID:24638036 rifampicin multiple interactions ISO RGD:1354090 6480464 4-phenylbutyric acid inhibits the reaction [Rifampin results in increased expression of EIF2AK3 mRNA], 4-phenylbutyric acid inhibits the reaction [Rifampin results in increased expression of EIF2AK3 protein] CTD PMID:27470132 rifampicin increases expression ISO RGD:1354090 6480464 Rifampin results in increased expression of EIF2AK3 mRNA, Rifampin results in increased expression of EIF2AK3 protein CTD PMID:27470132 rotenone increases phosphorylation ISO RGD:1354090 6480464 Rotenone results in increased phosphorylation of EIF2AK3 protein CTD PMID:19233273 , PMID:28359145 rotenone increases expression ISO RGD:1354090 6480464 Rotenone results in increased expression of EIF2AK3 protein CTD PMID:30141137 rotenone multiple interactions ISO RGD:1354090 6480464 geraniol inhibits the reaction [Rotenone results in increased expression of EIF2AK3 protein], PTPN1 protein affects the reaction [Rotenone results in increased phosphorylation of EIF2AK3 protein] CTD PMID:28359145 , PMID:30141137 rotenone multiple interactions ISO RGD:70884 6480464 Rotenone results in increased phosphorylation of and results in increased activity of EIF2AK3 protein CTD PMID:12486162 S-butyl-DL-homocysteine (S,R)-sulfoximine multiple interactions ISO RGD:1354090 6480464 Buthionine Sulfoximine promotes the reaction [pterostilbene results in increased phosphorylation of EIF2AK3 protein] CTD PMID:25341683 Salvianolic acid A multiple interactions EXP 6480464 salvianolic acid A inhibits the reaction [Lipopolysaccharides results in increased phosphorylation of EIF2AK3 protein] CTD PMID:31654708 SB 431542 multiple interactions ISO RGD:1354090 6480464 [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-5-benzo1, 3dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-ylbenzamide] results in increased expression of EIF2AK3 mRNA CTD PMID:27188386 SCH 23390 multiple interactions ISO RGD:70884 6480464 SCH 23390 inhibits the reaction [Cocaine results in increased expression of EIF2AK3 protein] CTD PMID:17303341 sertraline multiple interactions ISO RGD:1354090 6480464 MAP4K4 mutant form inhibits the reaction [Sertraline results in increased phosphorylation of EIF2AK3 protein], Sertraline results in increased expression of and results in increased phosphorylation of EIF2AK3 protein CTD PMID:24865413 sertraline increases expression ISO RGD:1354090 6480464 Sertraline results in increased expression of EIF2AK3 mRNA CTD PMID:24865413 silicon dioxide increases expression EXP 6480464 Silicon Dioxide results in increased expression of EIF2AK3 mRNA CTD PMID:23221170 sodium arsenite increases phosphorylation ISO RGD:1354090 6480464 sodium arsenite results in increased phosphorylation of EIF2AK3 protein CTD PMID:28973481 sodium arsenite increases phosphorylation EXP 6480464 sodium arsenite results in increased phosphorylation of EIF2AK3 protein CTD PMID:21911445 sodium dichromate decreases expression EXP 6480464 sodium bichromate results in decreased expression of EIF2AK3 mRNA CTD PMID:22155349 sodium fluoride increases expression ISO RGD:70884 6480464 Sodium Fluoride results in increased expression of EIF2AK3 mRNA CTD PMID:25132241 sorafenib multiple interactions ISO RGD:1354090 6480464 [sorafenib co-treated with vorinostat] promotes the reaction [FAS protein binds to EIF2AK3 protein] more ... CTD PMID:18787411 sorafenib increases phosphorylation ISO RGD:1354090 6480464 sorafenib results in increased phosphorylation of EIF2AK3 protein CTD PMID:17548474 sulforaphane multiple interactions ISO RGD:1354090 6480464 sulforafan promotes the reaction [arsenic trioxide results in increased expression of EIF2AK3 protein modified form] CTD PMID:22922937 sulforaphane increases expression ISO RGD:1354090 6480464 sulforafan results in increased expression of EIF2AK3 protein modified form CTD PMID:22922937 sunitinib decreases expression ISO RGD:1354090 6480464 Sunitinib results in decreased expression of EIF2AK3 mRNA CTD PMID:31533062 T-2 toxin decreases expression ISO RGD:1354090 6480464 T-2 Toxin results in decreased expression of EIF2AK3 mRNA CTD PMID:31863870 tauroursodeoxycholic acid multiple interactions ISO RGD:70884 6480464 ursodoxicoltaurine inhibits the reaction [Nicotine results in increased phosphorylation of EIF2AK3 protein] CTD PMID:26803847 tetrachloromethane multiple interactions ISO RGD:70884 6480464 [Dimethylformamide co-treated with Carbon Tetrachloride] results in increased expression of EIF2AK3 protein modified form CTD PMID:20097184 tetrachloromethane increases expression EXP 6480464 Carbon Tetrachloride results in increased expression of EIF2AK3 mRNA CTD PMID:31919559 tetrachloromethane increases phosphorylation EXP 6480464 Carbon Tetrachloride results in increased phosphorylation of EIF2AK3 protein CTD PMID:25827057 tetrachloromethane multiple interactions EXP 6480464 1-trifluoromethoxyphenyl-3-1-propionylpiperidine-4-ylurea inhibits the reaction [Carbon Tetrachloride results in increased phosphorylation of EIF2AK3 protein] CTD PMID:25827057 thapsigargin multiple interactions ISO RGD:1354090 6480464 1-1-methanesulfonylpiperidin-4-yl-3-4-trifluoromethoxyphenylurea inhibits the reaction [Thapsigargin results in increased phosphorylation of EIF2AK3 protein] more ... CTD PMID:20022965 more ... thapsigargin increases acetylation ISO RGD:70884 6480464 Thapsigargin results in increased acetylation of EIF2AK3 protein CTD PMID:29653943 thapsigargin increases phosphorylation ISO RGD:70884 6480464 Thapsigargin results in increased phosphorylation of EIF2AK3 protein CTD PMID:29653943 thapsigargin increases phosphorylation ISO RGD:1354090 6480464 Thapsigargin results in increased phosphorylation of EIF2AK3 protein CTD PMID:23576437 , PMID:26264395 thapsigargin increases expression ISO RGD:1354090 6480464 Thapsigargin results in increased expression of EIF2AK3 mRNA more ... CTD PMID:17963750 more ... thapsigargin increases phosphorylation EXP 6480464 Thapsigargin results in increased phosphorylation of EIF2AK3 protein CTD PMID:23576437 , PMID:24150608 thapsigargin multiple interactions ISO RGD:70884 6480464 EIF2AK3 gene mutant form inhibits the reaction [Thapsigargin results in increased phosphorylation of EIF2S1 protein] CTD PMID:16324875 thapsigargin multiple interactions EXP 6480464 1-1-methanesulfonylpiperidin-4-yl-3-4-trifluoromethoxyphenylurea inhibits the reaction [Thapsigargin results in increased phosphorylation of EIF2AK3 protein] more ... CTD PMID:17283163 more ... thapsigargin increases response to substance EXP 6480464 EIF2AK3 gene mutant form results in increased susceptibility to Thapsigargin CTD PMID:17283163 thymoquinone increases expression ISO RGD:1354090 6480464 thymoquinone results in increased expression of EIF2AK3 protein CTD PMID:29981725 titanium dioxide decreases expression EXP 6480464 titanium dioxide results in decreased expression of EIF2AK3 mRNA CTD PMID:29264374 titanium dioxide increases expression EXP 6480464 titanium dioxide results in increased expression of EIF2AK3 mRNA CTD PMID:31298478 , PMID:31769605 titanium dioxide increases phosphorylation ISO RGD:1354090 6480464 titanium dioxide results in increased phosphorylation of EIF2AK3 protein CTD PMID:30273564 titanium dioxide increases expression ISO RGD:1354090 6480464 titanium dioxide results in increased expression of EIF2AK3 mRNA CTD PMID:30273564 titanium dioxide multiple interactions EXP 6480464 Resveratrol inhibits the reaction [titanium dioxide results in increased expression of EIF2AK3 mRNA] CTD PMID:31298478 titanium dioxide affects expression ISO RGD:1354090 6480464 titanium dioxide affects the expression of EIF2AK3 protein CTD PMID:30273564 topotecan multiple interactions ISO RGD:70884 6480464 [oxaliplatin co-treated with Topotecan] results in decreased expression of EIF2AK3 mRNA CTD PMID:25729387 trichostatin A increases expression ISO RGD:1354090 6480464 trichostatin A results in increased expression of EIF2AK3 mRNA CTD PMID:24935251 triclocarban increases expression ISO RGD:1354090 6480464 triclocarban results in increased expression of EIF2AK3 protein modified form CTD PMID:30592132 tunicamycin multiple interactions EXP 6480464 1 more ... CTD PMID:16330322 more ... tunicamycin multiple interactions ISO RGD:1354090 6480464 Tunicamycin results in increased expression of and results in increased phosphorylation of EIF2AK3 protein CTD PMID:26551149 tunicamycin increases expression ISO RGD:1354090 6480464 Tunicamycin results in increased expression of EIF2AK3 mRNA, Tunicamycin results in increased expression of EIF2AK3 protein modified form CTD PMID:22378314 more ... tunicamycin increases phosphorylation EXP 6480464 Tunicamycin results in increased phosphorylation of EIF2AK3 protein CTD PMID:16330322 more ... tunicamycin increases expression EXP 6480464 Tunicamycin results in increased expression of EIF2AK3 mRNA CTD PMID:22959925 tunicamycin increases response to substance EXP 6480464 EIF2AK3 gene mutant form results in increased susceptibility to Tunicamycin CTD PMID:24648495 urethane increases expression ISO RGD:1354090 6480464 Urethane results in increased expression of EIF2AK3 mRNA CTD PMID:28818685 ursolic acid multiple interactions ISO RGD:1354090 6480464 EIF2AK3 mutant form inhibits the reaction [ursolic acid results in increased expression of DDIT3 protein] more ... CTD PMID:24802810 ursolic acid increases phosphorylation ISO RGD:1354090 6480464 ursolic acid results in increased phosphorylation of EIF2AK3 protein CTD PMID:24802810 valdecoxib decreases expression ISO RGD:70884 6480464 valdecoxib results in decreased expression of EIF2AK3 mRNA CTD PMID:24136188 valproic acid affects expression EXP 6480464 Valproic Acid affects the expression of EIF2AK3 mRNA CTD PMID:17963808 valproic acid multiple interactions ISO RGD:1354090 6480464 [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-5-benzo1, 3dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-ylbenzamide] results in increased expression of EIF2AK3 mRNA CTD PMID:27188386 valproic acid increases expression ISO RGD:1354090 6480464 Valproic Acid results in increased expression of EIF2AK3 mRNA CTD PMID:26272509 , PMID:28001369 valproic acid increases expression EXP 6480464 Valproic Acid results in increased expression of EIF2AK3 mRNA CTD PMID:19136453 , PMID:21427059 valsartan multiple interactions ISO RGD:70884 6480464 Valsartan inhibits the reaction [Cyclophosphamide results in increased phosphorylation of EIF2AK3 protein] CTD PMID:32197949 vorinostat multiple interactions ISO RGD:1354090 6480464 [sorafenib co-treated with vorinostat] promotes the reaction [FAS protein binds to EIF2AK3 protein] more ... CTD PMID:18787411 vorinostat increases phosphorylation ISO RGD:1354090 6480464 vorinostat results in increased phosphorylation of EIF2AK3 protein CTD PMID:20962572 zinc atom multiple interactions ISO RGD:1354090 6480464 [PCI 5002 co-treated with Zinc] results in increased expression of EIF2AK3 mRNA CTD PMID:18593933 zinc oxide increases phosphorylation EXP 6480464 Zinc Oxide analog results in increased phosphorylation of EIF2AK3 protein CTD PMID:25680694 zinc protoporphyrin multiple interactions ISO RGD:70884 6480464 zinc protoporphyrin promotes the reaction [[[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] co-treated with Ethanol] results in increased phosphorylation of EIF2AK3 protein], zinc protoporphyrin promotes the reaction [[[Oxygen deficiency co-treated with Blood Glucose deficiency] co-treated with [Oxygen co-treated with Blood Glucose]] results in increased phosphorylation of EIF2AK3 protein] CTD PMID:26747958 zinc(0) multiple interactions ISO RGD:1354090 6480464 [PCI 5002 co-treated with Zinc] results in increased expression of EIF2AK3 mRNA CTD PMID:18593933
