Gypa (glycophorin A) - Rat Genome Database
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Gene: Gypa (glycophorin A) Mus musculus
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Symbol: Gypa
Name: glycophorin A
RGD ID: 1619274
MGI Page MGI
Description: Exhibits identical protein binding activity. Involved in regulation of response to osmotic stress. Localizes to external side of plasma membrane and integral component of plasma membrane. Is expressed in yolk sac. Human ortholog(s) of this gene implicated in malaria. Orthologous to several human genes including GYPA (glycophorin A (MNS blood group)); PARTICIPATES IN malaria pathway; INTERACTS WITH 17alpha-ethynylestradiol; 2,3,7,8-tetrachlorodibenzodioxine; arsane.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: AI853584; CD235; CD235a; G; glycophorin-A; GPA
RGD Orthologs
Human
Bonobo
Dog
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39881,220,674 - 81,237,414 (+)NCBIGRCm39mm39
GRCm38880,494,045 - 80,510,785 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl880,493,781 - 80,510,542 (+)EnsemblGRCm38mm10GRCm38
MGSCv37883,017,944 - 83,034,684 (+)NCBIGRCm37mm9NCBIm37
MGSCv36883,389,289 - 83,406,230 (+)NCBImm8
Celera884,765,672 - 84,782,460 (+)NCBICelera
Cytogenetic Map8C2NCBI
cM Map838.27NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
malaria  (ISO)
Skin Neoplasms  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

Additional References at PubMed
PMID:2043106   PMID:2753361   PMID:7613034   PMID:7896738   PMID:8662744   PMID:8889548   PMID:9398835   PMID:9490702   PMID:9747880   PMID:10349636   PMID:10848813   PMID:11042159  
PMID:11044609   PMID:11076861   PMID:11217851   PMID:12466851   PMID:12477932   PMID:12940824   PMID:14563645   PMID:14749362   PMID:15170228   PMID:15947087   PMID:16141072   PMID:16141073  
PMID:17431131   PMID:17675555   PMID:19084340   PMID:19210546   PMID:21455273   PMID:21873635   PMID:22566683   PMID:26446156   PMID:26527618   PMID:27114509   PMID:28701737  


Genomics

Comparative Map Data
Gypa
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39881,220,674 - 81,237,414 (+)NCBIGRCm39mm39
GRCm38880,494,045 - 80,510,785 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl880,493,781 - 80,510,542 (+)EnsemblGRCm38mm10GRCm38
MGSCv37883,017,944 - 83,034,684 (+)NCBIGRCm37mm9NCBIm37
MGSCv36883,389,289 - 83,406,230 (+)NCBImm8
Celera884,765,672 - 84,782,460 (+)NCBICelera
Cytogenetic Map8C2NCBI
cM Map838.27NCBI
GYPA
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl4144,109,303 - 144,140,751 (-)EnsemblGRCh38hg38GRCh38
GRCh384144,109,303 - 144,140,854 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh374145,030,456 - 145,061,904 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 364145,249,906 - 145,281,294 (-)NCBINCBI36hg18NCBI36
Build 344145,388,061 - 145,419,449NCBI
Celera4142,359,859 - 142,391,286 (-)NCBI
Cytogenetic Map4q31.21NCBI
HuRef4140,759,973 - 140,791,405 (-)NCBIHuRef
CHM1_14145,007,517 - 145,038,987 (-)NCBICHM1_1
GYPA
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.14147,987,563 - 148,148,082 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl4147,987,750 - 148,019,005 (-)Ensemblpanpan1.1panPan2
PanPan1.1 Ensembl4148,117,479 - 148,148,315 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v04136,455,397 - 136,486,858 (-)NCBIMhudiblu_PPA_v0panPan3
GYPA
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl1543,018,708 - 43,049,665 (-)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.11543,018,705 - 43,049,726 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
GYPA
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1884,037,574 - 84,067,096 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2889,194,118 - 89,222,888 (+)NCBISscrofa10.2Sscrofa10.2susScr3
GYPA
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1790,702,645 - 90,739,106 (-)NCBI
Gypa
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046248533,132,961 - 3,158,461 (-)NCBI

Position Markers
AI853584  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm38880,509,505 - 80,509,588UniSTSGRCm38
MGSCv37883,033,404 - 83,033,487UniSTSGRCm37
Celera884,781,180 - 84,781,263UniSTS
Cytogenetic Map8C2UniSTS
cM Map836.0UniSTS
Whitehead/MRC_RH8858.62UniSTS
Gypa  
Mouse AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map8C2UniSTS
cM Map836.0UniSTS


QTLs in Region (GRCm38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
4140967Bmd39_mbone mineral density 39 (mouse)Not determined832016544117238700Mouse
1558875Eae31_mexperimental allergic encephalomyelitis susceptibility 31 (mouse)Not determined834642776114837007Mouse
1301013Capsq4_mcapsaicin sensitivity related QTL 4 (mouse)Not determined83616300092728652Mouse
27226754Femd6_mfemur midshaft diameter 6, 10 week (mouse)837400000109600000Mouse
12904744Carcdq1_mcardiac collagen deposition QTL 1 (mouse)83970925694689598Mouse
1301717Adip4_madiposity 4 (mouse)Not determined84763703081637146Mouse
10766453Char11_mP. chabaudi malaria resistance QTL 11 (mouse)84763703081637146Mouse
1301441Skull11_mskull morphology 11 (mouse)Not determined84773713481737254Mouse
1357715Alaa3_malopecia areata 3 (mouse)Not determined84879293982793021Mouse
14746987Manh64_mmandible shape 64 (mouse)85005330684053306Mouse
14747005Mancz7_mmandible centroid size 7 (mouse)85005330684053306Mouse
14700686Civq3_mcerebral infarct volume QTL 3 (mouse)85188219185882191Mouse
1301506Aevm1_mautoimmune extremity vasculitis in MRL mice 1 (mouse)Not determined85428781788287993Mouse
1301952Im3_mimmunoregulatory 3 (mouse)Not determined85470661488706763Mouse
10412287Carg3_mCandida albicans resistance gene 3 (mouse)Not determined85554502889545028Mouse
11353828Gf7_mgonadal fat pad weight 7 (mouse)85820147992201479Mouse
10043975Obq31_mobesity QTL 31 (mouse)Not determined85840977692409776Mouse
1301688Orch6_mautoimmune orchitis resistance 6 (mouse)Not determined86078685094786976Mouse
4141285Tgq18_mtriglyceride QTL 18 (mouse)Not determined6346010797460107Mouse
4141797Skmw16_mskeletal muscle weight 16 (mouse)Not determined86393954797939696Mouse
1357787Vtbt5_mvertebral trabecular bone trait 5 (mouse)Not determined86535776899357920Mouse
10043992Hbnr11_mHeligmosomoides bakeri nematode resistance 11 (mouse)Not determined86560020799600347Mouse
10766466Char12_mP. chabaudi malaria resistance QTL 12 (mouse)86826982782600347Mouse
1301767Fcsa2_mfemoral cross-sectional area 2 (mouse)Not determined870305375104305495Mouse
4142283Imraq2_mimmune response to AAV2 QTL 2 (mouse)Not determined870305375104305495Mouse
1558780Idd22_minsulin dependent diabetes susceptibility 22 (mouse)Not determined871102903105103009Mouse
4141395Char2a_mP. chabaudi malaria resistance QTL 2a (mouse)Not determined7113678390202598Mouse
4142023W3q5_mweight 3 weeks QTL 5 (mouse)Not determined71287817123895615Mouse
1357708Orq1_movulation rate QTL 1 (mouse)Not determined871287817123895615Mouse
1301872Cd4ts3_mCD4 T cell subset 3 (mouse)Not determined871396181105396393Mouse
1300920Pitm3_mprion incubation time 3 (mouse)Not determined873202495107202598Mouse
27095912Pglq14_mpelvic girdle length QTL 14, 16 week (mouse)873400000126100000Mouse
1558890Lith18_mlithogenic gene 18 (mouse)Not determined875675517109675623Mouse
1357470Obq16_mobesity QTL 16 (mouse)Not determined875685348109685497Mouse
1301808Nhdlq1_mnon-HDL QTL 1 (mouse)Not determined875685348109685497Mouse
1301874Hdlq16_mHDL QTL 16 (mouse)Not determined875685348109685497Mouse
10412234Nhdlq14_mnon-HDL QTL 14 (mouse)Not determined875685348109685497Mouse
1301099Cbm2_mcerebellum weight 2 (mouse)Not determined878518613112518703Mouse
1301581Char2_mP. chabaudi malaria resistance QTL 2 (mouse)Not determined879082178113082403Mouse
12904012Cfq10_mconditioned fear QTL 10 (mouse)88006677589014359Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:276
Count of miRNA genes:238
Interacting mature miRNAs:252
Transcripts:ENSMUST00000063359
Prediction methods:Miranda
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSMUST00000063359   ⟹   ENSMUSP00000070836
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38.p6 Ensembl880,493,781 - 80,510,542 (+)Ensembl
RefSeq Acc Id: NM_010369   ⟹   NP_034499
RefSeq Status: VALIDATED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39881,220,674 - 81,237,414 (+)NCBI
GRCm38880,494,045 - 80,510,785 (+)NCBI
MGSCv37883,017,944 - 83,034,684 (+)RGD
Celera884,765,672 - 84,782,460 (+)RGD
cM Map8 ENTREZGENE
Sequence:
Reference Sequences
RefSeq Acc Id: NP_034499   ⟸   NM_010369
- UniProtKB: P14220 (UniProtKB/Swiss-Prot),   Q3TRN7 (UniProtKB/TrEMBL),   Q3TZH8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSMUSP00000070836   ⟸   ENSMUST00000063359

Promoters
RGD ID:8667559
Promoter ID:EPDNEW_M11811
Type:multiple initiation site
Name:Gypa_1
Description:Mus musculus glycophorin A , mRNA.
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm38880,494,045 - 80,494,105EPDNEW
RGD ID:6843282
Promoter ID:MM_KWN:54957
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:Spleen
Transcripts:NM_010369
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv36883,017,861 - 83,018,361 (+)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:95880 AgrOrtholog
Ensembl Genes ENSMUSG00000051839 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSMUSP00000070836 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSMUST00000063359 ENTREZGENE, UniProtKB/Swiss-Prot
InterPro Glycophorin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Glycophorin_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:14934 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:95880 ENTREZGENE
NCBI Gene 14934 ENTREZGENE
PANTHER PTHR13813 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Gypa PhenoGen
PIRSF Glycophorin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE GLYCOPHORIN_A UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniGene Mm.13123 ENTREZGENE
UniProt GLPA_MOUSE UniProtKB/Swiss-Prot, ENTREZGENE
  Q3TRN7 ENTREZGENE, UniProtKB/TrEMBL
  Q3TZH8 ENTREZGENE, UniProtKB/TrEMBL
  Q3UKI2_MOUSE UniProtKB/TrEMBL