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Gene: Cebpa (CCAAT/enhancer binding protein (C/EBP), alpha) Mus musculus
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Symbol: Cebpa
Name: CCAAT/enhancer binding protein (C/EBP), alpha
RGD ID: 10325
Description: Exhibits several functions, including DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and identical protein binding activity. Involved in several processes, including animal organ development; positive regulation of cell differentiation; and regulation of transcription by RNA polymerase II. Localizes to nucleus and transcription regulator complex. Is expressed in several structures, including adipose tissue; brain; early conceptus; genitourinary system; and integumental system. Used to study acute myeloid leukemia. Human ortholog(s) of this gene implicated in acute myeloid leukemia. Orthologous to human CEBPA (CCAAT enhancer binding protein alpha).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: C/ebp; C/EBP alpha; C/ebpalpha; CBF-A; CCAAT/enhancer-binding protein alpha; Ceb; Cebp
Orthologs:
Homo sapiens (human) : CEBPA (CCAAT enhancer binding protein alpha)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Cebpa (CCAAT/enhancer binding protein alpha)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cebpa (CCAAT enhancer binding protein alpha)
Pan paniscus (bonobo/pygmy chimpanzee) : CEBPA (CCAAT enhancer binding protein alpha)
Canis lupus familiaris (dog) : CEBPA (CCAAT enhancer binding protein alpha)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cebpa (CCAAT enhancer binding protein alpha)
Sus scrofa (pig) : CEBPA (CCAAT enhancer binding protein alpha)
Chlorocebus sabaeus (African green monkey) : CEBPA (CCAAT enhancer binding protein alpha)
Heterocephalus glaber (naked mole-rat) : Cebpa (CCAAT enhancer binding protein alpha)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39734,818,718 - 34,821,353 (+)NCBI
GRCm38735,119,293 - 35,121,928 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl735,119,293 - 35,121,928 (+)EnsemblGRCm38mm10GRCm38
MGSCv37735,904,312 - 35,906,947 (+)NCBIGRCm37mm9NCBIm37
MGSCv36734,828,063 - 34,830,688 (+)NCBImm8
Celera730,255,122 - 30,257,756 (+)NCBICelera
Cytogenetic Map7B2NCBI
cM Map721.02NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters

Additional Information

External Database Links
 
More on Cebpa
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 10325
Created: 2000-05-25
Species: Mus musculus
Last Modified: 2020-10-13
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.