Adam33 (a disintegrin and metallopeptidase domain 33) - Rat Genome Database

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Gene: Adam33 (a disintegrin and metallopeptidase domain 33) Mus musculus
Analyze
Symbol: Adam33
Name: a disintegrin and metallopeptidase domain 33
RGD ID: 1313213
MGI Page MGI
Description: Predicted to enable metal ion binding activity and metallopeptidase activity. Predicted to be located in membrane. Is expressed in several structures, including brain; genitourinary system; gut; hemolymphoid system gland; and integumental system. Human ortholog(s) of this gene implicated in asthma; chronic obstructive pulmonary disease; and rhinitis. Orthologous to human ADAM33 (ADAM metallopeptidase domain 33).
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: a disintegrin and metalloprotease domain 33; ADAM 33; Adaml; disintegrin and metalloproteinase domain-containing protein 33
RGD Orthologs
Human
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: GRCm39 - Mouse Genome Assembly GRCm39
Position:
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392130,892,739 - 130,905,734 (-)NCBIGRCm39mm39
GRCm39 Ensembl2130,892,511 - 130,905,734 (-)Ensembl
GRCm382131,050,819 - 131,063,814 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2131,050,591 - 131,063,814 (-)EnsemblGRCm38mm10GRCm38
MGSCv372130,876,553 - 130,889,550 (-)NCBIGRCm37mm9NCBIm37
MGSCv362130,742,550 - 130,755,255 (-)NCBImm8
Celera2132,275,541 - 132,288,553 (-)NCBICelera
Cytogenetic Map2F1NCBI
cM Map263.26NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Mammalian Phenotype
References

References - curated
# Reference Title Reference Citation
1. The genetic association database. Becker KG, etal., Nat Genet. 2004 May;36(5):431-2.
2. Polymorphisms in ADAM33 are associated with allergic rhinitis due to Japanese cedar pollen. Cheng L, etal., Clin Exp Allergy. 2004 Aug;34(8):1192-201.
3. Increased expression of ADAM33 and ADAM8 with disease progression in asthma. Foley SC, etal., J Allergy Clin Immunol. 2007 Apr;119(4):863-71. Epub 2007 Mar 6.
4. The effects of Th2 cytokines on the expression of ADAM33 in allergen-induced chronic airway inflammation. Jie Z, etal., Respir Physiol Neurobiol. 2009 Sep 30;168(3):289-94. Epub 2009 Jul 25.
5. MGDs mouse GO annotations MGD data from the GO Consortium
6. Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. Okazaki Y, etal., Nature. 2002 Dec 5;420(6915):563-73.
7. ADAM33 gene polymorphisms in chronic obstructive pulmonary disease. Pabst S, etal., Eur J Med Res. 2009 Dec 7;14 Suppl 4:182-6.
8. Zhonghua jie he he hu xi za zhi = Zhonghua jiehe he huxi zazhi = Chinese journal of tuberculosis and respiratory diseases Qiu YM, etal., Zhonghua Jie He He Hu Xi Za Zhi. 2007 Jul;30(7):518-21.
9. Mouse MP Annotation Import Pipeline RGD automated import pipeline
10. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
11. Adam33 polymorphisms are associated with COPD and lung function in long-term tobacco smokers. Sadeghnejad A, etal., Respir Res. 2009 Mar 12;10:21.
12. Genetic susceptibility to respiratory syncytial virus bronchiolitis in preterm children is associated with airway remodeling genes and innate immune genes. Siezen CL, etal., Pediatr Infect Dis J. 2009 Apr;28(4):333-5.
13. Association of ADAM33 gene polymorphisms with adult allergic asthma and rhinitis in a Chinese Han population. Su D, etal., BMC Med Genet. 2008 Sep 9;9:82.
14. A Six-SNP haplotype of ADAM33 is associated with asthma in a population of Cartagena, Colombia. Vergara CI, etal., Int Arch Allergy Immunol. 2010;152(1):32-40. Epub 2009 Nov 24.
15. Lack of association between ADAM33 gene and asthma in a Chinese population. Wang P, etal., Int J Immunogenet. 2006 Aug;33(4):303-6.
16. Association of ADAM33 gene polymorphisms with COPD in a northeastern Chinese population. Wang X, etal., BMC Med Genet. 2009 Dec 10;10:132.
Additional References at PubMed
PMID:8889548   PMID:10086356   PMID:10349636   PMID:11042159   PMID:11076861   PMID:11217851   PMID:11814695   PMID:11897009   PMID:12110844   PMID:12477932   PMID:12972401   PMID:15063736  
PMID:15657107   PMID:16079176   PMID:16141072   PMID:16141073   PMID:16943435   PMID:19665773   PMID:20562862   PMID:21677750  


Genomics

Comparative Map Data
Adam33
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm392130,892,739 - 130,905,734 (-)NCBIGRCm39mm39
GRCm39 Ensembl2130,892,511 - 130,905,734 (-)Ensembl
GRCm382131,050,819 - 131,063,814 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2131,050,591 - 131,063,814 (-)EnsemblGRCm38mm10GRCm38
MGSCv372130,876,553 - 130,889,550 (-)NCBIGRCm37mm9NCBIm37
MGSCv362130,742,550 - 130,755,255 (-)NCBImm8
Celera2132,275,541 - 132,288,553 (-)NCBICelera
Cytogenetic Map2F1NCBI
cM Map263.26NCBI
ADAM33
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38203,667,975 - 3,682,010 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl203,667,965 - 3,682,246 (-)EnsemblGRCh38hg38GRCh38
GRCh37203,648,622 - 3,662,657 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36203,596,620 - 3,610,738 (-)NCBINCBI36hg18NCBI36
Build 34203,596,620 - 3,610,738NCBI
Celera203,710,486 - 3,724,619 (-)NCBI
Cytogenetic Map20p13NCBI
HuRef203,596,952 - 3,611,071 (-)NCBIHuRef
CHM1_1203,648,928 - 3,663,053 (-)NCBICHM1_1
T2T-CHM13v2.0203,698,909 - 3,712,954 (-)NCBI
Adam33
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.23118,262,395 - 118,283,461 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl3118,271,029 - 118,283,461 (-)Ensembl
Rnor_6.03123,595,018 - 123,607,549 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl3123,595,560 - 123,607,352 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.03130,094,363 - 130,106,835 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.43118,727,883 - 118,752,218 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.13118,633,395 - 118,670,271 (-)NCBI
Celera3117,080,790 - 117,093,950 (-)NCBICelera
Cytogenetic Map3q36NCBI
Adam33
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541514,524,354 - 14,533,700 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541514,523,517 - 14,535,701 (-)NCBIChiLan1.0ChiLan1.0
ADAM33
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1203,507,630 - 3,521,720 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl203,508,620 - 3,521,628 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0203,750,158 - 3,764,262 (-)NCBIMhudiblu_PPA_v0panPan3
ADAM33
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12417,668,377 - 17,682,217 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2417,668,500 - 17,681,209 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2417,489,886 - 17,512,110 (+)NCBI
ROS_Cfam_1.02418,080,386 - 18,101,065 (+)NCBI
ROS_Cfam_1.0 Ensembl2418,086,847 - 18,100,334 (+)Ensembl
UMICH_Zoey_3.12417,673,802 - 17,695,814 (+)NCBI
UNSW_CanFamBas_1.02417,793,269 - 17,807,567 (+)NCBI
UU_Cfam_GSD_1.02418,113,989 - 18,134,652 (+)NCBI
Adam33
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024408640166,573,648 - 166,587,722 (+)NCBI
SpeTri2.0NW_00493648515,005,329 - 15,018,063 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
ADAM33
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1732,023,091 - 32,037,880 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11732,023,102 - 32,038,464 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21736,350,589 - 36,365,562 (+)NCBISscrofa10.2Sscrofa10.2susScr3
ADAM33
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1234,352,514 - 34,366,694 (-)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl234,353,505 - 34,366,559 (-)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366607110,083,660 - 10,097,934 (+)NCBIVero_WHO_p1.0
Adam33
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247414,766,306 - 4,775,501 (-)EnsemblHetGla_female_1.0hetGla2
HetGla 1.0NW_0046247414,764,508 - 4,778,174 (-)NCBIHetGla_female_1.0hetGla2

Position Markers
BB284546  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm382131,051,043 - 131,051,131UniSTSGRCm38
MGSCv372130,876,779 - 130,876,867UniSTSGRCm37
Celera2132,275,767 - 132,275,855UniSTS
Cytogenetic Map2F1UniSTS
cM Map273.9UniSTS
Whitehead/MRC_RH21639.75UniSTS
UniSTS:234536  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm382131,051,030 - 131,051,233UniSTSGRCm38
MGSCv372130,876,766 - 130,876,969UniSTSGRCm37
Celera2132,275,754 - 132,275,957UniSTS
Cytogenetic Map2F1UniSTS
cM Map273.9UniSTS
PMC88886P1  
Mouse AssemblyChrPosition (strand)SourceJBrowse
GRCm382131,050,905 - 131,051,348UniSTSGRCm38
MGSCv372130,876,641 - 130,877,084UniSTSGRCm37
Celera2132,275,629 - 132,276,072UniSTS
Cytogenetic Map2F1UniSTS
cM Map273.9UniSTS


QTLs in Region (GRCm39)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
1302174Dssc2_mdextran sodium sulfate induced colitis QTL2 (mouse)Not determined224224632148700377Mouse
4141854T2dm2sa_mtype 2 diabetes mellitus 2 in SMXA RI mice (mouse)Not determined229307947148374934Mouse
1301344Lith1_mlithogenic gene 1 (mouse)Not determined245347635145312647Mouse
13824983Vclq1_mcurvilinear velocity QTL 1 (mouse)261830344136841920Mouse
5491197Mobq5_mmultigenic obesity QTL 5 (mouse)Not determined265269746162518926Mouse
4141155Plast2b_mplasma plant sterol 2b (mouse)Not determined284013198148522175Mouse
10412082Hylaq1_mHyperlocomotor activity related QTL 1 (mouse)Not determined284013198148667470Mouse
5491196Mobq6_mmultigenic obesity QTL 6 (mouse)Not determined285724269180896594Mouse
27226761Feml18_mfemur length 18, 16 week (mouse)294230345154241920Mouse
11049569Lmr28d_mleishmaniasis resistance 28d (mouse)297123370131123532Mouse
11049568Lmr28c_mleishmaniasis resistance 28c (mouse)297123370131123532Mouse
12904935Edlmmq2_mextensor digitorum longus muscle mass QTL 2 (mouse)297210364131210364Mouse
12904954Gmmq2_mgastrocnemius muscle mass QTL 2 (mouse)297210364131210364Mouse
4141802Ignpq1_mIgA nephropathy QTL 1 (mouse)Not determined2100824060134824269Mouse
1302203Gvhd3_mgraft-versus host disease 3 (mouse)Not determined2100942930134943090Mouse
1301330Tbbmd2_mtotal body bone mineral density 2 (mouse)Not determined2100942930134943090Mouse
1302071Fembrs1_mfemur breaking strength 1 (mouse)Not determined2100942930134943090Mouse
27226788Feml13_mfemur length 13, 10 week (mouse)2102630345159941920Mouse
11038702Ltpr2_mLeishmania tropica response 2 (mouse)2103095716167212356Mouse
1301825Pbrgcsf1_mperipheral blood stem cell response to granulocyte colony stimulating factor 1 (mouse)Not determined2106233580140233729Mouse
10043875Bw25_mbody weight QTL 25 (mouse)Not determined2107255676141255676Mouse
1301087Bbaa15_mB.burgdorferi-associated arthritis 15 (mouse)Not determined2110489658144489807Mouse
10045885Cplaq15_mcircadian period of locomotor activity 15 (mouse)Not determined2110916118154354667Mouse
1558990Skmw9_mskeletal muscle weight 9 (mouse)Not determined2111173704145173821Mouse
1300793Pcfm2_mperiosteal circumference and femur length 2 (mouse)Not determined2111173704145173821Mouse
1301905Lgth2_mbody length 2 (mouse)Not determined2111173704145173821Mouse
1301755Hrq1_mheart rate quantitative locus 1 (mouse)Not determined2111173704145173821Mouse
1301201Chab1_mcholesterol absorption 1 (mouse)Not determined2111551028145551163Mouse
1302033Nsv1_mNeuroadapted Sindbis viral RNA level 1 (mouse)Not determined2111623386145623526Mouse
11039520Ltpr2h_mLeishmania tropica response 2h (mouse)2112212746146213005Mouse
11038699Ltpr2b_mLeishmania tropica response 2b (mouse)2112212746146213005Mouse
11038700Ltpr2a_mLeishmania tropica response 2a (mouse)2112212746146213005Mouse
1301029T2dm3_mtype 2 diabetes mellitus 3 (mouse)Not determined2114288075132714157Mouse
11039521Ltpr2g_mLeishmania tropica response 2g (mouse)2115212857149212994Mouse
11038696Ltpr2f_mLeishmania tropica response 2f (mouse)2115212857149212994Mouse
1301295Prdt1_mprion disease incubation time 1 (mouse)Not determined2116077623150077741Mouse
1558881Ses7_msalmonella enteritidis susceptibility 7 (mouse)Not determined2116306330150306474Mouse
1301618Bglu1_mblood glucose level 1 (mouse)Not determined2117942930174324863Mouse
12910795Pwbwq5_mpost-weaning body weight QTL 5 (mouse)2118589253160611165Mouse
12910799Pwgrq2_mpre-weaning growth rate QTL 2 (mouse)2118589253160611165Mouse
12910812Pwgrq1_mpre-weaning growth rate QTL 1 (mouse)2118589253160611165Mouse
12910814Pwbwq1_mpre-weaning body weight QTL 1 (mouse)2118589253160611165Mouse
1300712El2_mepilepsy 2 (mouse)Not determined2122207146142532135Mouse
1301294Hrtfm5_mheart failure modifier 5 (mouse)Not determined2122883015156883131Mouse
1301066Otx2m2_morthodenticle homolog 2 (Drosophila) modifier 2 (mouse)Not determined2123231973148700377Mouse
1301822Pgia2_mproteoglycan induced arthritis 2 (mouse)Not determined2123937311157937424Mouse
27226749Femd10_mfemur midshaft diameter 10, 16 week (mouse)2124441920168241920Mouse
13506763Tbvq1_mtrabecular bone volume QTL 1 (mouse)2126041920135441920Mouse
1302143Bwq5_mbody weight (mouse)Not determined2127664019161664118Mouse
1301031Bdln3_mbody length 3 (mouse)Not determined2127664019161664118Mouse
1558989Gnf4_mgrowth and fatness 4 (mouse)Not determined2128173704132714157Mouse
12880427V25Dq3_mvitamin D inactive form serum level QTL 3 (mouse)2129341920163341920Mouse

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:2506
Count of miRNA genes:777
Interacting mature miRNAs:1023
Transcripts:ENSMUST00000052104, ENSMUST00000110232, ENSMUST00000124481, ENSMUST00000127343, ENSMUST00000128828, ENSMUST00000132071, ENSMUST00000132436, ENSMUST00000134742, ENSMUST00000135149, ENSMUST00000147333, ENSMUST00000149625, ENSMUST00000183552, ENSMUST00000184921
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001163529 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_033615 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_136922 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006498576 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011239248 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011239249 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011239250 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011239251 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011239252 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011239255 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_001780409 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_001780411 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_004937534 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_004937535 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_866209 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB059632 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB059633 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF386072 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF472524 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK048367 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK053825 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK086734 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK138517 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL833771 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AW048228 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY054984 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY382193 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY382194 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY953137 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC138139 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH466519 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENSMUST00000052104   ⟹   ENSMUSP00000052486
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2130,893,029 - 130,905,734 (-)Ensembl
GRCm38.p6 Ensembl2131,051,109 - 131,063,814 (-)Ensembl
RefSeq Acc Id: ENSMUST00000110232   ⟹   ENSMUSP00000105861
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2130,892,737 - 130,905,734 (-)Ensembl
GRCm38.p6 Ensembl2131,050,817 - 131,063,814 (-)Ensembl
RefSeq Acc Id: ENSMUST00000124481
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2130,903,969 - 130,905,463 (-)Ensembl
GRCm38.p6 Ensembl2131,062,049 - 131,063,543 (-)Ensembl
RefSeq Acc Id: ENSMUST00000127343
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2130,895,141 - 130,895,979 (-)Ensembl
GRCm38.p6 Ensembl2131,053,221 - 131,054,059 (-)Ensembl
RefSeq Acc Id: ENSMUST00000128828
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2130,892,511 - 130,895,956 (-)Ensembl
GRCm38.p6 Ensembl2131,050,591 - 131,054,036 (-)Ensembl
RefSeq Acc Id: ENSMUST00000132071
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2130,895,442 - 130,896,449 (-)Ensembl
GRCm38.p6 Ensembl2131,053,522 - 131,054,529 (-)Ensembl
RefSeq Acc Id: ENSMUST00000132436
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2130,892,745 - 130,905,489 (-)Ensembl
GRCm38.p6 Ensembl2131,050,825 - 131,063,569 (-)Ensembl
RefSeq Acc Id: ENSMUST00000134742
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2130,893,030 - 130,898,401 (-)Ensembl
GRCm38.p6 Ensembl2131,051,110 - 131,056,481 (-)Ensembl
RefSeq Acc Id: ENSMUST00000135149   ⟹   ENSMUSP00000122608
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2130,892,783 - 130,898,287 (-)Ensembl
GRCm38.p6 Ensembl2131,050,863 - 131,056,367 (-)Ensembl
RefSeq Acc Id: ENSMUST00000147333   ⟹   ENSMUSP00000117097
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2130,899,450 - 130,905,433 (-)Ensembl
GRCm38.p6 Ensembl2131,057,530 - 131,063,513 (-)Ensembl
RefSeq Acc Id: ENSMUST00000149625
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2130,895,010 - 130,896,436 (-)Ensembl
GRCm38.p6 Ensembl2131,053,090 - 131,054,516 (-)Ensembl
RefSeq Acc Id: ENSMUST00000183552   ⟹   ENSMUSP00000139344
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2130,892,795 - 130,905,465 (-)Ensembl
GRCm38.p6 Ensembl2131,050,875 - 131,063,545 (-)Ensembl
RefSeq Acc Id: ENSMUST00000184921   ⟹   ENSMUSP00000139366
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm39 Ensembl2130,894,962 - 130,896,446 (-)Ensembl
GRCm38.p6 Ensembl2131,053,042 - 131,054,526 (-)Ensembl
RefSeq Acc Id: NM_001163529   ⟹   NP_001157001
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392130,892,742 - 130,905,734 (-)NCBI
GRCm382131,050,822 - 131,063,814 (-)NCBI
MGSCv372130,876,553 - 130,889,550 (-)RGD
Celera2132,275,541 - 132,288,553 (-)RGD
cM Map2 ENTREZGENE
Sequence:
RefSeq Acc Id: NM_033615   ⟹   NP_291093
RefSeq Status: REVIEWED
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392130,892,742 - 130,905,734 (-)NCBI
GRCm382131,050,822 - 131,063,814 (-)NCBI
MGSCv372130,876,553 - 130,889,550 (-)RGD
Celera2132,275,541 - 132,288,553 (-)RGD
cM Map2 ENTREZGENE
Sequence:
RefSeq Acc Id: NR_136922
RefSeq Status: REVIEWED
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392130,892,742 - 130,905,734 (-)NCBI
GRCm382131,050,822 - 131,063,814 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006498576   ⟹   XP_006498639
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392130,892,739 - 130,905,486 (-)NCBI
GRCm382131,050,819 - 131,063,566 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011239248   ⟹   XP_011237550
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392130,892,739 - 130,905,457 (-)NCBI
GRCm382131,050,819 - 131,063,513 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011239249   ⟹   XP_011237551
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392130,892,739 - 130,900,658 (-)NCBI
GRCm382131,050,819 - 131,058,738 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011239250   ⟹   XP_011237552
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392130,892,739 - 130,905,448 (-)NCBI
GRCm382131,050,819 - 131,063,533 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011239251   ⟹   XP_011237553
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392130,892,739 - 130,900,658 (-)NCBI
GRCm382131,050,819 - 131,058,738 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011239252   ⟹   XP_011237554
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392130,895,129 - 130,905,489 (-)NCBI
GRCm382131,053,209 - 131,063,570 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011239255   ⟹   XP_011237557
RefSeq Status:
Type: CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392130,895,850 - 130,905,493 (-)NCBI
GRCm382131,053,930 - 131,063,573 (-)NCBI
Sequence:
RefSeq Acc Id: XR_001780409
RefSeq Status:
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392130,892,739 - 130,905,489 (-)NCBI
GRCm382131,050,819 - 131,063,569 (-)NCBI
Sequence:
RefSeq Acc Id: XR_001780411
RefSeq Status:
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392130,892,742 - 130,905,493 (-)NCBI
GRCm382131,050,819 - 131,063,573 (-)NCBI
Sequence:
RefSeq Acc Id: XR_004937534
RefSeq Status:
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392130,892,739 - 130,905,488 (-)NCBI
Sequence:
RefSeq Acc Id: XR_004937535
RefSeq Status:
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392130,892,742 - 130,905,493 (-)NCBI
Sequence:
RefSeq Acc Id: XR_866209
RefSeq Status:
Type: NON-CODING
Position:
Mouse AssemblyChrPosition (strand)Source
GRCm392130,892,742 - 130,905,490 (-)NCBI
GRCm382131,050,819 - 131,063,571 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_291093   ⟸   NM_033615
- Peptide Label: isoform 1 preproprotein
- UniProtKB: Q923W9 (UniProtKB/Swiss-Prot),   A2AP51 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001157001   ⟸   NM_001163529
- Peptide Label: isoform 2 precursor
- UniProtKB: A2AP51 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006498639   ⟸   XM_006498576
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_011237550   ⟸   XM_011239248
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_011237553   ⟸   XM_011239251
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_011237551   ⟸   XM_011239249
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_011237552   ⟸   XM_011239250
- Peptide Label: isoform X2
- Sequence:
RefSeq Acc Id: XP_011237554   ⟸   XM_011239252
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_011237557   ⟸   XM_011239255
- Peptide Label: isoform X4
- Sequence:
RefSeq Acc Id: ENSMUSP00000052486   ⟸   ENSMUST00000052104
RefSeq Acc Id: ENSMUSP00000139366   ⟸   ENSMUST00000184921
RefSeq Acc Id: ENSMUSP00000139344   ⟸   ENSMUST00000183552
RefSeq Acc Id: ENSMUSP00000105861   ⟸   ENSMUST00000110232
RefSeq Acc Id: ENSMUSP00000117097   ⟸   ENSMUST00000147333
RefSeq Acc Id: ENSMUSP00000122608   ⟸   ENSMUST00000135149
Protein Domains
Disintegrin   EGF-like   Peptidase M12B

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q923W9-F1-model_v2 AlphaFold Q923W9 1-797 view protein structure

Promoters
RGD ID:6830702
Promoter ID:MM_KWN:31781
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_4Hour
Transcripts:OTTMUST00000036902,   UC008MKL.1
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv362130,881,481 - 130,881,981 (-)MPROMDB
RGD ID:6830701
Promoter ID:MM_KWN:31782
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:BoneMarrow_0Hour,   BoneMarrow_4Hour
Transcripts:ENSMUST00000077541,   NM_001163529,   NM_033615,   OTTMUST00000036899,   OTTMUST00000036900,   OTTMUST00000036901,   OTTMUST00000037280
Position:
Mouse AssemblyChrPosition (strand)Source
MGSCv362130,889,064 - 130,889,564 (-)MPROMDB

Additional Information

Database Acc Id Source(s)
AGR Gene MGI:1341813 AgrOrtholog
Ensembl Genes ENSMUSG00000027318 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSMUSP00000052486 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000105861 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUSP00000117097.2 UniProtKB/TrEMBL
  ENSMUSP00000122608 ENTREZGENE
  ENSMUSP00000122608.2 UniProtKB/TrEMBL
  ENSMUSP00000139344 UniProtKB/Swiss-Prot
  ENSMUSP00000139366.2 UniProtKB/TrEMBL
Ensembl Transcript ENSMUST00000052104 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000110232 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSMUST00000132436 ENTREZGENE
  ENSMUST00000135149 ENTREZGENE
  ENSMUST00000135149.8 UniProtKB/TrEMBL
  ENSMUST00000147333.2 UniProtKB/TrEMBL
  ENSMUST00000183552 UniProtKB/Swiss-Prot
  ENSMUST00000184921.8 UniProtKB/TrEMBL
Gene3D-CATH 3.40.390.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  4.10.70.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
InterPro ADAM_Cys-rich UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Disintegrin_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Disintegrin_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Disintegrin_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EGF-like_dom UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  MetalloPept_cat_dom_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Peptidase_M12B UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Peptidase_M12B_N UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Reprolysin_adamalysin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report mmu:110751 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
MGD MGI:1341813 ENTREZGENE
NCBI Gene 110751 ENTREZGENE
Pfam ADAM_CR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Disintegrin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Pep_M12B_propep UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Reprolysin UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PhenoGen Adam33 PhenoGen
PRINTS DISINTEGRIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE ADAM_MEPRO UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DISINTEGRIN_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DISINTEGRIN_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EGF_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  EGF_3 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  ZINC_PROTEASE UniProtKB/Swiss-Prot
SMART ACR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  DISIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF57552 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A2AP51 ENTREZGENE, UniProtKB/TrEMBL
  ADA33_MOUSE UniProtKB/Swiss-Prot
  F6Z4C4_MOUSE UniProtKB/TrEMBL
  F7CIM2_MOUSE UniProtKB/TrEMBL
  Q58GH7_MOUSE UniProtKB/TrEMBL
  Q6TYY9_MOUSE UniProtKB/TrEMBL
  Q6TYZ0_MOUSE UniProtKB/TrEMBL
  Q8R465_MOUSE UniProtKB/TrEMBL
  Q923W9 ENTREZGENE
  V9GXX4_MOUSE UniProtKB/TrEMBL
UniProt Secondary Q8R5G5 UniProtKB/Swiss-Prot