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Gene: Pak6 (p21 (RAC1) activated kinase 6) Mus musculus
Symbol: Pak6
Name: p21 (RAC1) activated kinase 6
RGD ID: 1314704
Description: Predicted to have protein serine/threonine kinase activity. Involved in learning or memory; locomotory behavior; and neuron projection morphogenesis. Predicted to localize to cell junction; cytoplasm; and nuclear lumen. Is expressed in central nervous system; retina; submandibular gland primordium; and tooth. Human ortholog(s) of this gene implicated in clear cell renal cell carcinoma. Orthologous to several human genes including BUB1B-PAK6 (BUB1B-PAK6 readthrough); PARTICIPATES IN epidermal growth factor/neuregulin signaling pathway; renal cell carcinoma pathway; T cell receptor signaling pathway; INTERACTS WITH 2,3,7,8-tetrachlorodibenzodioxine; 3,4-methylenedioxymethamphetamine; 3-methylcholanthrene.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: 4732456M09; p21 protein (Cdc42/Rac)-activated kinase 6; p21-activated kinase 6; PAK-6; serine/threonine-protein kinase PAK 6
Homo sapiens (human) : PAK6 (p21 (RAC1) activated kinase 6)  HGNC  Alliance
Rattus norvegicus (Norway rat) : Pak6 (p21 (RAC1) activated kinase 6)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Pak6 (p21 (RAC1) activated kinase 6)
Pan paniscus (bonobo/pygmy chimpanzee) : PAK6 (p21 (RAC1) activated kinase 6)
Canis lupus familiaris (dog) : PAK6 (p21 (RAC1) activated kinase 6)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : LOC101957470 (serine/threonine-protein kinase PAK 6)
Sus scrofa (pig) : PAK6 (p21 (RAC1) activated kinase 6)
Chlorocebus sabaeus (African green monkey) : PAK6 (p21 (RAC1) activated kinase 6)
Heterocephalus glaber (naked mole-rat) : Pak6 (p21 (RAC1) activated kinase 6)
more info ...
Latest Assembly: GRCm38 - Mouse Genome Assembly GRCm38
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
GRCm392118,493,531 - 118,528,501 (+)NCBI
GRCm382118,663,045 - 118,698,020 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl2118,663,303 - 118,698,020 (+)EnsemblGRCm38mm10GRCm38
MGSCv372118,489,313 - 118,523,756 (+)NCBIGRCm37mm9NCBIm37
MGSCv362118,354,744 - 118,388,677 (+)NCBImm8
Celera2119,818,133 - 119,852,648 (+)NCBICelera
Cytogenetic Map2E5NCBI
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
QTLs in Region (GRCm38)
miRNA Target Status



Nucleotide Sequences
Protein Sequences

Additional Information

External Database Links
Nomenclature History
More on Pak6
Alliance Gene
Ensembl Gene
JBrowse: mm9 mm10
MGI Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1314704
Created: 2005-01-12
Species: Mus musculus
Last Modified: 2020-10-13
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.