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G |
Polb |
DNA polymerase beta |
multiple interactions |
EXP |
nervonic acid binds to and results in decreased activity of POLB protein; nervonic acid binds to and results in decreased activity of POLB protein mutant form |
CTD |
PMID:16996474 |
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NCBI chr16:69,379,438...69,402,710
Ensembl chr16:69,379,400...69,404,812
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G |
Acta2 |
actin alpha 2, smooth muscle |
increases expression multiple interactions |
ISO |
lysophosphatidic acid results in increased expression of ACTA2 mRNA N-(4-chlorophenyl)-1-((3-(furan-2-yl)phenyl)carbonyl)piperidine-3-carboxamide inhibits the reaction [lysophosphatidic acid results in increased expression of ACTA2 mRNA] |
CTD |
PMID:24706986 |
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NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554
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G |
Akt1 |
AKT serine/threonine kinase 1 |
multiple interactions increases phosphorylation |
ISO EXP |
2-(1H-indazol-4-yl)-6-(4-methanesulfonylpiperazin-1-ylmethyl)-4-morpholin-4-ylthieno(3,2-d)pyrimidine inhibits the reaction [lysophosphatidic acid results in increased phosphorylation of AKT1 protein]; Resveratrol inhibits the reaction [lysophosphatidic acid results in increased phosphorylation of AKT1 protein] 1-Butanol inhibits the reaction [lysophosphatidic acid results in increased phosphorylation of AKT1 protein]; exoenzyme C3, Clostridium botulinum inhibits the reaction [lysophosphatidic acid results in increased phosphorylation of AKT1 protein] |
CTD |
PMID:14769825 PMID:17550345 PMID:20103642 |
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NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
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G |
Alox5 |
arachidonate 5-lipoxygenase |
multiple interactions |
ISO |
ALOX5 protein promotes the reaction [lysophosphatidic acid results in increased abundance of Hydrogen Peroxide]; Masoprocol inhibits the reaction [ALOX5 protein promotes the reaction [lysophosphatidic acid results in increased abundance of Hydrogen Peroxide]]; zileuton inhibits the reaction [ALOX5 protein promotes the reaction [lysophosphatidic acid results in increased abundance of Hydrogen Peroxide]] |
CTD |
PMID:10698703 |
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NCBI chr 4:149,531,329...149,578,696
Ensembl chr 4:149,531,515...149,578,743
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G |
Alpl |
alkaline phosphatase, biomineralization associated |
multiple interactions |
ISO |
[Lithocholic Acid co-treated with lysophosphatidic acid] results in increased activity of ALPL protein |
CTD |
PMID:19646460 |
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NCBI chr 5:149,951,397...150,006,424
Ensembl chr 5:149,951,409...150,006,446
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G |
Bcar1 |
BCAR1 scaffold protein, Cas family member |
increases phosphorylation |
ISO |
lysophosphatidic acid results in increased phosphorylation of BCAR1 protein |
CTD |
PMID:11792571 |
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NCBI chr19:39,679,215...39,713,907
Ensembl chr19:39,679,204...39,713,907
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G |
Bcl2 |
BCL2, apoptosis regulator |
increases expression |
ISO |
lysophosphatidic acid analog results in increased expression of BCL2 protein; lysophosphatidic acid results in increased expression of BCL2 protein |
CTD |
PMID:23251428 |
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NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
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G |
C5 |
complement C5 |
increases expression |
ISO |
lysophosphatidic acid results in increased expression of HC protein |
CTD |
PMID:25822713 |
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NCBI chr 3:18,270,696...18,361,994
Ensembl chr 3:18,270,696...18,361,994
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G |
Casp3 |
caspase 3 |
multiple interactions |
ISO |
lysophosphatidic acid analog inhibits the reaction [cobaltous chloride results in increased activity of CASP3 protein]; lysophosphatidic acid inhibits the reaction [cobaltous chloride results in increased activity of CASP3 protein] |
CTD |
PMID:23251428 |
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NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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G |
Ccl12 |
C-C motif chemokine ligand 12 |
increases expression multiple interactions |
ISO |
lysophosphatidic acid results in increased expression of CCL12 protein 3-(4-(4-((1-(2-chlorophenyl)ethoxy)carbonyl amino)-3-methyl-5-isoxazolyl) benzylsulfanyl) propanoic acid inhibits the reaction [lysophosphatidic acid results in increased expression of CCL12 protein] |
CTD |
PMID:25822713 |
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NCBI chr10:67,070,230...67,071,780
Ensembl chr10:67,070,230...67,071,780
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G |
Ccl28 |
C-C motif chemokine ligand 28 |
multiple interactions increases expression |
ISO |
3-(4-(4-((1-(2-chlorophenyl)ethoxy)carbonyl amino)-3-methyl-5-isoxazolyl) benzylsulfanyl) propanoic acid inhibits the reaction [lysophosphatidic acid results in increased expression of CCL28 protein] |
CTD |
PMID:25822713 |
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NCBI chr 2:51,601,354...51,625,999
Ensembl chr 2:51,601,331...51,625,997
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G |
Ccn1 |
cellular communication network factor 1 |
multiple interactions increases expression |
ISO |
3-(4-(4-((1-(2-chlorophenyl)ethoxy)carbonyl amino)-3-methyl-5-isoxazolyl) benzylsulfanyl) propanoic acid inhibits the reaction [lysophosphatidic acid results in increased expression of CCN1 protein] |
CTD |
PMID:25822713 |
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NCBI chr 2:234,562,410...234,565,370
Ensembl chr 2:234,562,408...234,565,484
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G |
Ccn2 |
cellular communication network factor 2 |
increases expression multiple interactions |
EXP ISO |
lysophosphatidic acid results in increased expression of CCN2 protein N-(4-chlorophenyl)-1-((3-(furan-2-yl)phenyl)carbonyl)piperidine-3-carboxamide inhibits the reaction [lysophosphatidic acid results in increased expression of CCN2 mRNA] Simvastatin inhibits the reaction [lysophosphatidic acid results in increased expression of CCN2 protein]; Y 27632 inhibits the reaction [lysophosphatidic acid results in increased expression of CCN2 protein] |
CTD |
PMID:15200425 PMID:24706986 |
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NCBI chr 1:20,802,199...20,805,315
Ensembl chr 1:20,802,199...20,805,734
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G |
Col1a2 |
collagen type I alpha 2 chain |
increases expression multiple interactions |
ISO |
lysophosphatidic acid results in increased expression of COL1A2 mRNA N-(4-chlorophenyl)-1-((3-(furan-2-yl)phenyl)carbonyl)piperidine-3-carboxamide inhibits the reaction [lysophosphatidic acid results in increased expression of COL1A2 mRNA] |
CTD |
PMID:24706986 |
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NCBI chr 4:32,563,938...32,598,868
Ensembl chr 4:32,563,381...32,598,867
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G |
Csf1 |
colony stimulating factor 1 |
increases expression |
ISO |
lysophosphatidic acid results in increased expression of CSF1 protein |
CTD |
PMID:25822713 |
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NCBI chr 2:195,377,215...195,396,608
Ensembl chr 2:195,377,215...195,411,704
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G |
Cxcl12 |
C-X-C motif chemokine ligand 12 |
increases expression multiple interactions |
ISO |
lysophosphatidic acid results in increased expression of CXCL12 protein 3-(4-(4-((1-(2-chlorophenyl)ethoxy)carbonyl amino)-3-methyl-5-isoxazolyl) benzylsulfanyl) propanoic acid inhibits the reaction [lysophosphatidic acid results in increased expression of CXCL12 protein] |
CTD |
PMID:25822713 |
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NCBI chr 4:150,388,326...150,401,173
Ensembl chr 4:150,388,325...150,401,168
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G |
Cxcl16 |
C-X-C motif chemokine ligand 16 |
increases expression multiple interactions |
ISO |
lysophosphatidic acid results in increased expression of CXCL16 protein 3-(4-(4-((1-(2-chlorophenyl)ethoxy)carbonyl amino)-3-methyl-5-isoxazolyl) benzylsulfanyl) propanoic acid inhibits the reaction [lysophosphatidic acid results in increased expression of CXCL16 protein] |
CTD |
PMID:25822713 |
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NCBI chr10:55,166,721...55,171,316
Ensembl chr10:55,166,723...55,171,592
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G |
Cxcr1 |
C-X-C motif chemokine receptor 1 |
multiple interactions decreases expression |
ISO |
lysophosphatidic acid inhibits the reaction [CXCR1 protein binds to LPAR1 protein]; lysophosphatidic acid results in decreased expression of [CXCR1 protein binds to LPAR1 protein] lysophosphatidic acid results in decreased expression of CXCR1 mRNA |
CTD |
PMID:16224106 |
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NCBI chr 9:75,766,894...75,771,079
Ensembl chr 9:75,766,770...75,771,084
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G |
Dgka |
diacylglycerol kinase, alpha |
multiple interactions |
ISO |
DGKA protein promotes the reaction [lysophosphatidic acid results in increased activity of PIP5K1A protein] |
CTD |
PMID:10913605 |
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NCBI chr 7:1,148,734...1,175,324
Ensembl chr 7:1,148,735...1,175,110
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G |
Egfr |
epidermal growth factor receptor |
multiple interactions increases phosphorylation |
ISO |
GNA13 mutant form inhibits the reaction [lysophosphatidic acid results in increased phosphorylation of EGFR protein]; Pertussis Toxin inhibits the reaction [lysophosphatidic acid results in increased phosphorylation of EGFR protein]; resveratrol inhibits the reaction [lysophosphatidic acid results in increased phosphorylation of EGFR protein] |
CTD |
PMID:23127547 |
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NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382
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G |
Eif4ebp1 |
eukaryotic translation initiation factor 4E binding protein 1 |
multiple interactions increases phosphorylation |
EXP |
1-Butanol inhibits the reaction [lysophosphatidic acid results in increased phosphorylation of EIF4EBP1 protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [lysophosphatidic acid results in increased phosphorylation of EIF4EBP1 protein]; 2-butanol inhibits the reaction [lysophosphatidic acid results in increased phosphorylation of EIF4EBP1 protein]; exoenzyme C3, Clostridium botulinum inhibits the reaction [lysophosphatidic acid results in increased phosphorylation of EIF4EBP1 protein] |
CTD |
PMID:14769825 |
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NCBI chr16:64,792,595...64,805,984
Ensembl chr16:64,790,226...64,805,984
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G |
Enpp2 |
ectonucleotide pyrophosphatase/phosphodiesterase 2 |
multiple interactions decreases expression |
ISO EXP |
1,2-bis(2-aminophenoxy)ethane N,N,N',N'-tetraacetic acid acetoxymethyl ester inhibits the reaction [[ENPP2 protein co-treated with Capsaicin] results in increased abundance of lysophosphatidic acid]; 3-(2-methoxybenzylamino)-2-phenylpiperidine inhibits the reaction [[ENPP2 protein co-treated with Capsaicin] results in increased abundance of lysophosphatidic acid]; [[Capsaicin results in increased chemical synthesis of Lysophosphatidylcholines] which results in increased secretion of Lysophosphatidylcholines] promotes the reaction [ENPP2 results in increased chemical synthesis of lysophosphatidic acid]; [[ONO-8430506 results in decreased activity of ENPP2 protein] which results in decreased abundance of lysophosphatidic acid] which results in decreased expression of NFE2L2; [[ONO-8430506 results in decreased activity of ENPP2 protein] which results in decreased chemical synthesis of and results in decreased abundance of lysophosphatidic acid] which results in increased expression of ENPP2 mRNA; [ENPP2 protein co-treated with Capsaicin] results in increased abundance of lysophosphatidic acid; [ENPP2 protein co-treated with Lysophosphatidylcholines] results in increased chemical synthesis of lysophosphatidic acid; [ONO-8430506 results in decreased activity of ENPP2 protein] which results in decreased abundance of lysophosphatidic acid; [ONO-8430506 results in decreased activity of ENPP2 protein] which results in decreased chemical synthesis of and results in decreased abundance of lysophosphatidic acid; arachidonyltrifluoromethane inhibits the reaction [[ENPP2 protein co-treated with Capsaicin] results in increased abundance of lysophosphatidic acid]; bisindolylmaleimide I inhibits the reaction [[ENPP2 protein co-treated with Capsaicin] results in increased abundance of lysophosphatidic acid]; Dizocilpine Maleate inhibits the reaction [[ENPP2 protein co-treated with Capsaicin] results in increased abundance of lysophosphatidic acid]; IL1B protein inhibits the reaction [lysophosphatidic acid results in decreased expression of ENPP2 protein]; TNF protein inhibits the reaction [lysophosphatidic acid results in decreased expression of ENPP2 protein]; U 0126 inhibits the reaction [[ENPP2 protein co-treated with Capsaicin] results in increased abundance of lysophosphatidic acid]; xestospongin C inhibits the reaction [[ENPP2 protein co-treated with Capsaicin] results in increased abundance of lysophosphatidic acid] lysophosphatidic acid inhibits the reaction [ENPP2 mutant form results in decreased expression of MBP mRNA] |
CTD |
PMID:18594965 PMID:19014389 PMID:24599971 PMID:24747415 PMID:25398768 PMID:25896349 More...
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NCBI chr 7:86,202,345...86,325,050
Ensembl chr 7:86,202,350...86,324,827
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G |
Epo |
erythropoietin |
multiple interactions |
ISO |
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [[lysophosphatidic acid co-treated with KITLG protein co-treated with EPO protein] results in increased expression of TFRC protein]; [lysophosphatidic acid co-treated with KITLG protein co-treated with EPO protein] results in increased expression of GATA1 mRNA; [lysophosphatidic acid co-treated with KITLG protein co-treated with EPO protein] results in increased expression of TFRC mRNA; [lysophosphatidic acid co-treated with KITLG protein co-treated with EPO protein] results in increased expression of TFRC protein; lysophosphatidic acid promotes the reaction [[KITLG protein co-treated with EPO protein] results in increased expression of GATA1 mRNA]; lysophosphatidic acid promotes the reaction [[KITLG protein co-treated with EPO protein] results in increased expression of GYPA mRNA]; lysophosphatidic acid promotes the reaction [[KITLG protein co-treated with EPO protein] results in increased expression of TFRC mRNA]; lysophosphatidic acid promotes the reaction [[KITLG protein co-treated with EPO protein] results in increased expression of TFRC protein]; Quercetin inhibits the reaction [[lysophosphatidic acid co-treated with KITLG protein co-treated with EPO protein] results in increased expression of GATA1 mRNA]; Quercetin inhibits the reaction [[lysophosphatidic acid co-treated with KITLG protein co-treated with EPO protein] results in increased expression of TFRC mRNA]; Quercetin inhibits the reaction [[lysophosphatidic acid co-treated with KITLG protein co-treated with EPO protein] results in increased expression of TFRC protein]; WP1066 inhibits the reaction [[lysophosphatidic acid co-treated with KITLG protein co-treated with EPO protein] results in increased expression of TFRC protein] |
CTD |
PMID:21915944 |
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NCBI chr12:19,204,258...19,207,948
Ensembl chr12:19,204,508...19,207,946
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G |
Gata1 |
GATA binding protein 1 |
multiple interactions |
ISO |
[lysophosphatidic acid co-treated with KITLG protein co-treated with EPO protein] results in increased expression of GATA1 mRNA; lysophosphatidic acid promotes the reaction [[KITLG protein co-treated with EPO protein] results in increased expression of GATA1 mRNA]; Quercetin inhibits the reaction [[lysophosphatidic acid co-treated with KITLG protein co-treated with EPO protein] results in increased expression of GATA1 mRNA] |
CTD |
PMID:21915944 |
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NCBI chr X:14,529,706...14,537,530
Ensembl chr X:14,529,702...14,537,530
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G |
Gna13 |
G protein subunit alpha 13 |
multiple interactions |
ISO |
GNA13 mutant form inhibits the reaction [lysophosphatidic acid results in increased phosphorylation of EGFR protein] |
CTD |
PMID:23127547 |
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NCBI chr10:94,337,939...94,370,774
Ensembl chr10:94,337,725...94,370,774
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G |
Gypa |
glycophorin A |
multiple interactions |
ISO |
lysophosphatidic acid promotes the reaction [[KITLG protein co-treated with EPO protein] results in increased expression of GYPA mRNA] |
CTD |
PMID:21915944 |
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NCBI chr19:27,450,304...27,465,940
Ensembl chr19:27,450,308...27,465,822
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G |
Hif1a |
hypoxia inducible factor 1 subunit alpha |
multiple interactions increases expression |
ISO |
L-4F peptide inhibits the reaction [lysophosphatidic acid results in increased expression of HIF1A protein]; resveratrol inhibits the reaction [lysophosphatidic acid results in increased expression of HIF1A protein] [lysophosphatidic acid results in increased expression of HIF1A protein] which results in increased expression of VEGFA mRNA; [lysophosphatidic acid results in increased expression of HIF1A protein] which results in increased expression of VEGFA protein; lysophosphatidic acid results in increased expression of HIF1A protein |
CTD |
PMID:17919812 PMID:22537771 |
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NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
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G |
Hspb1 |
heat shock protein family B (small) member 1 |
multiple interactions increases phosphorylation |
EXP |
MK2i peptide inhibits the reaction [lysophosphatidic acid results in increased phosphorylation of HSPB1 protein]; SB 203580 inhibits the reaction [lysophosphatidic acid results in increased phosphorylation of HSPB1 protein] |
CTD |
PMID:20864298 |
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NCBI chr12:20,794,014...20,795,675
Ensembl chr12:20,794,028...20,795,743
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G |
Il1b |
interleukin 1 beta |
multiple interactions |
ISO |
IL1B protein inhibits the reaction [lysophosphatidic acid results in decreased expression of ENPP2 protein] |
CTD |
PMID:25896349 |
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NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
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G |
Il6 |
interleukin 6 |
increases secretion |
ISO |
lysophosphatidic acid results in increased secretion of IL6 protein |
CTD |
PMID:21821728 |
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NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
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G |
Il6st |
interleukin 6 cytokine family signal transducer |
multiple interactions increases expression |
ISO |
3-(4-(4-((1-(2-chlorophenyl)ethoxy)carbonyl amino)-3-methyl-5-isoxazolyl) benzylsulfanyl) propanoic acid inhibits the reaction [lysophosphatidic acid results in increased expression of IL6ST protein] |
CTD |
PMID:25822713 |
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NCBI chr 2:44,065,979...44,106,255
Ensembl chr 2:44,066,130...44,109,936
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G |
Kitlg |
KIT ligand |
multiple interactions |
ISO |
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [[lysophosphatidic acid co-treated with KITLG protein co-treated with EPO protein] results in increased expression of TFRC protein]; [lysophosphatidic acid co-treated with KITLG protein co-treated with EPO protein] results in increased expression of GATA1 mRNA; [lysophosphatidic acid co-treated with KITLG protein co-treated with EPO protein] results in increased expression of TFRC mRNA; [lysophosphatidic acid co-treated with KITLG protein co-treated with EPO protein] results in increased expression of TFRC protein; lysophosphatidic acid promotes the reaction [[KITLG protein co-treated with EPO protein] results in increased expression of GATA1 mRNA]; lysophosphatidic acid promotes the reaction [[KITLG protein co-treated with EPO protein] results in increased expression of GYPA mRNA]; lysophosphatidic acid promotes the reaction [[KITLG protein co-treated with EPO protein] results in increased expression of TFRC mRNA]; lysophosphatidic acid promotes the reaction [[KITLG protein co-treated with EPO protein] results in increased expression of TFRC protein]; Quercetin inhibits the reaction [[lysophosphatidic acid co-treated with KITLG protein co-treated with EPO protein] results in increased expression of GATA1 mRNA]; Quercetin inhibits the reaction [[lysophosphatidic acid co-treated with KITLG protein co-treated with EPO protein] results in increased expression of TFRC mRNA]; Quercetin inhibits the reaction [[lysophosphatidic acid co-treated with KITLG protein co-treated with EPO protein] results in increased expression of TFRC protein]; WP1066 inhibits the reaction [[lysophosphatidic acid co-treated with KITLG protein co-treated with EPO protein] results in increased expression of TFRC protein] |
CTD |
PMID:21915944 |
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NCBI chr 7:34,896,075...34,977,215
Ensembl chr 7:34,896,053...34,977,214
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G |
Kng1 |
kininogen 1 |
multiple interactions |
EXP |
KNG1 protein inhibits the reaction [[Wortmannin co-treated with lysophosphatidic acid] results in increased phosphorylation of PTK2 protein] |
CTD |
PMID:10537051 |
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NCBI chr11:77,812,757...77,835,555
Ensembl chr11:77,812,752...77,835,555
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G |
Lama3 |
laminin subunit alpha 3 |
increases expression |
ISO |
lysophosphatidic acid results in increased expression of LAMA3 mRNA |
CTD |
PMID:15541073 |
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NCBI chr18:3,523,168...3,751,722
Ensembl chr18:3,523,133...3,751,353
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G |
Lamb3 |
laminin subunit beta 3 |
increases expression |
ISO |
lysophosphatidic acid results in increased expression of LAMB3 mRNA |
CTD |
PMID:15541073 |
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NCBI chr13:104,833,810...104,875,405
Ensembl chr13:104,833,873...104,875,405
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G |
Lamc2 |
laminin subunit gamma 2 |
increases expression |
ISO |
lysophosphatidic acid results in increased expression of LAMC2 mRNA |
CTD |
PMID:15541073 |
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NCBI chr13:65,284,664...65,344,164
Ensembl chr13:65,284,664...65,344,200
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G |
Lpar1 |
lysophosphatidic acid receptor 1 |
increases response to substance multiple interactions |
ISO |
LPAR1 protein results in increased susceptibility to lysophosphatidic acid LPAR1 protein affects the reaction [lysophosphatidic acid results in increased stability of and affects the localization of NFE2L2 protein]; lysophosphatidic acid inhibits the reaction [CXCR1 protein binds to LPAR1 protein]; lysophosphatidic acid results in decreased expression of [CXCR1 protein binds to LPAR1 protein] |
CTD |
PMID:16224106 PMID:16809448 PMID:25398768 |
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NCBI chr 5:73,229,047...73,347,874
Ensembl chr 5:73,229,625...73,369,895
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G |
Lpar3 |
lysophosphatidic acid receptor 3 |
multiple interactions |
ISO |
Endocannabinoids inhibits the reaction [lysophosphatidic acid binds to and results in increased activity of LPAR3 protein]; lysophosphatidic acid binds to and results in increased activity of LPAR3 protein |
CTD |
PMID:30102254 |
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NCBI chr 2:235,125,234...235,193,916
Ensembl chr 2:235,149,065...235,193,357
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G |
Lpar5 |
lysophosphatidic acid receptor 5 |
multiple interactions |
ISO |
Endocannabinoids inhibits the reaction [lysophosphatidic acid binds to and results in increased activity of LPAR5 protein]; lysophosphatidic acid binds to and results in increased activity of LPAR5 protein |
CTD |
PMID:30102254 |
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NCBI chr 4:157,870,493...157,883,979
Ensembl chr 4:157,881,796...157,882,950
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G |
Lpar6 |
lysophosphatidic acid receptor 6 |
multiple interactions |
ISO |
lysophosphatidic acid binds to and results in increased activity of LPAR6 protein |
CTD |
PMID:18297070 |
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NCBI chr15:48,416,548...48,418,357
Ensembl chr15:48,416,544...48,422,331
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G |
Mapk1 |
mitogen activated protein kinase 1 |
multiple interactions increases phosphorylation |
ISO EXP |
Hydrogen Peroxide promotes the reaction [lysophosphatidic acid results in increased phosphorylation of MAPK1 protein]; resveratrol inhibits the reaction [lysophosphatidic acid results in increased phosphorylation of MAPK1 protein] 1-Butanol inhibits the reaction [PLD1 protein affects the reaction [lysophosphatidic acid results in increased phosphorylation of MAPK1 protein]]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [lysophosphatidic acid results in increased phosphorylation of MAPK1 protein]; Pertussis Toxin inhibits the reaction [lysophosphatidic acid results in increased phosphorylation of MAPK1 protein]; PLD1 protein affects the reaction [lysophosphatidic acid results in increased phosphorylation of MAPK1 protein]; U 0126 inhibits the reaction [lysophosphatidic acid results in increased phosphorylation of MAPK1 protein] |
CTD |
PMID:11243883 PMID:12657697 PMID:15081308 PMID:17919812 PMID:21179406 |
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NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
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G |
Mapk3 |
mitogen activated protein kinase 3 |
multiple interactions increases phosphorylation |
ISO EXP |
Hydrogen Peroxide promotes the reaction [lysophosphatidic acid results in increased phosphorylation of MAPK3 protein]; resveratrol inhibits the reaction [lysophosphatidic acid results in increased phosphorylation of MAPK3 protein] 1-Butanol inhibits the reaction [PLD1 protein affects the reaction [lysophosphatidic acid results in increased phosphorylation of MAPK3 protein]]; 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [lysophosphatidic acid results in increased phosphorylation of MAPK3 protein]; Pertussis Toxin inhibits the reaction [lysophosphatidic acid results in increased phosphorylation of MAPK3 protein]; PLD1 protein affects the reaction [lysophosphatidic acid results in increased phosphorylation of MAPK3 protein]; U 0126 inhibits the reaction [lysophosphatidic acid results in increased phosphorylation of MAPK3 protein] |
CTD |
PMID:11243883 PMID:12657697 PMID:15081308 PMID:17919812 PMID:21179406 |
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NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
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G |
Mbp |
myelin basic protein |
multiple interactions |
EXP |
lysophosphatidic acid inhibits the reaction [ENPP2 mutant form results in decreased expression of MBP mRNA] |
CTD |
PMID:18594965 |
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NCBI chr18:75,855,878...75,966,404
Ensembl chr18:75,855,878...75,966,404
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G |
Mmp9 |
matrix metallopeptidase 9 |
multiple interactions increases expression |
ISO |
gefitinib inhibits the reaction [lysophosphatidic acid results in increased expression of MMP9 mRNA]; gefitinib promotes the reaction [resveratrol inhibits the reaction [lysophosphatidic acid results in increased expression of MMP9 mRNA]]; resveratrol inhibits the reaction [lysophosphatidic acid results in increased expression of MMP9 mRNA]; resveratrol promotes the reaction [gefitinib inhibits the reaction [lysophosphatidic acid results in increased expression of MMP9 mRNA]] |
CTD |
PMID:23127547 |
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NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
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G |
Mtor |
mechanistic target of rapamycin kinase |
increases phosphorylation |
EXP |
lysophosphatidic acid results in increased phosphorylation of MTOR protein |
CTD |
PMID:14769825 |
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NCBI chr 5:158,884,856...158,994,311
Ensembl chr 5:158,884,804...158,994,311
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G |
Myl9 |
myosin light chain 9 |
increases phosphorylation multiple interactions |
ISO |
lysophosphatidic acid results in increased phosphorylation of MYL9 protein Farnesol analog inhibits the reaction [lysophosphatidic acid results in increased phosphorylation of MYL9 protein]; geranylgeraniol analog inhibits the reaction [lysophosphatidic acid results in increased phosphorylation of MYL9 protein] |
CTD |
PMID:24587105 |
|
NCBI chr 3:145,281,943...145,288,333
Ensembl chr 3:145,281,937...145,288,333
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G |
Mylk |
myosin light chain kinase |
affects response to substance |
ISO |
MYLK protein affects the susceptibility to lysophosphatidic acid |
CTD |
PMID:10640419 |
|
NCBI chr11:65,783,008...66,030,239
Ensembl chr11:65,783,008...66,030,261
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G |
Nfe2l2 |
NFE2 like bZIP transcription factor 2 |
multiple interactions |
ISO |
LPAR1 protein affects the reaction [lysophosphatidic acid results in increased stability of and affects the localization of NFE2L2 protein]; lysophosphatidic acid results in increased stability of and affects the localization of NFE2L2 protein [[ONO-8430506 results in decreased activity of ENPP2 protein] which results in decreased abundance of lysophosphatidic acid] which results in decreased expression of NFE2L2 |
CTD |
PMID:25398768 |
|
NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
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G |
Nppa |
natriuretic peptide A |
multiple interactions increases expression |
EXP |
Pertussis Toxin inhibits the reaction [lysophosphatidic acid results in increased expression of NPPA protein]; Y 27632 inhibits the reaction [lysophosphatidic acid results in increased expression of NPPA protein] |
CTD |
PMID:15081308 PMID:25449040 |
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NCBI chr 5:158,429,042...158,430,351
Ensembl chr 5:158,429,042...158,430,351
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G |
Pip5k1a |
phosphatidylinositol-4-phosphate 5-kinase, type 1, alpha |
multiple interactions increases activity |
ISO |
1-Butanol inhibits the reaction [lysophosphatidic acid results in increased activity of PIP5K1A protein]; DGKA protein promotes the reaction [lysophosphatidic acid results in increased activity of PIP5K1A protein] |
CTD |
PMID:10913605 |
|
NCBI chr 2:182,628,299...182,671,584
Ensembl chr 2:182,628,300...182,671,598
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G |
Plau |
plasminogen activator, urokinase |
multiple interactions increases expression |
ISO |
gefitinib inhibits the reaction [lysophosphatidic acid results in increased expression of PLAU mRNA]; gefitinib promotes the reaction [resveratrol inhibits the reaction [lysophosphatidic acid results in increased expression of PLAU mRNA]]; resveratrol inhibits the reaction [lysophosphatidic acid results in increased expression of PLAU mRNA]; resveratrol promotes the reaction [gefitinib inhibits the reaction [lysophosphatidic acid results in increased expression of PLAU mRNA]] |
CTD |
PMID:23127547 |
|
NCBI chr15:3,456,230...3,462,732
Ensembl chr15:3,456,232...3,462,775
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G |
Pld1 |
phospholipase D1 |
multiple interactions increases activity |
EXP |
1-Butanol inhibits the reaction [PLD1 protein affects the reaction [lysophosphatidic acid results in increased phosphorylation of MAPK1 protein]]; 1-Butanol inhibits the reaction [PLD1 protein affects the reaction [lysophosphatidic acid results in increased phosphorylation of MAPK3 protein]]; bisindolylmaleimide I inhibits the reaction [lysophosphatidic acid results in increased activity of PLD1 protein]; Pertussis Toxin inhibits the reaction [lysophosphatidic acid results in increased activity of PLD1 protein]; PLD1 protein affects the reaction [lysophosphatidic acid results in increased phosphorylation of MAPK1 protein]; PLD1 protein affects the reaction [lysophosphatidic acid results in increased phosphorylation of MAPK3 protein]; toxB protein, Clostridium difficile inhibits the reaction [lysophosphatidic acid results in increased phosphorylation of PLD1 protein] |
CTD |
PMID:11243883 PMID:14769825 |
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NCBI chr 2:110,849,205...111,047,304
Ensembl chr 2:110,893,608...111,047,692
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G |
Ppp1r12a |
protein phosphatase 1, regulatory subunit 12A |
increases phosphorylation multiple interactions |
EXP |
lysophosphatidic acid results in increased phosphorylation of PPP1R12A protein Y 27632 inhibits the reaction [lysophosphatidic acid results in increased phosphorylation of PPP1R12A protein] |
CTD |
PMID:25449040 |
|
NCBI chr 7:43,482,808...43,593,689
Ensembl chr 7:43,482,803...43,593,425
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G |
Ptk2 |
protein tyrosine kinase 2 |
increases phosphorylation multiple interactions |
ISO EXP |
lysophosphatidic acid results in increased phosphorylation of PTK2 protein [wortmannin co-treated with lysophosphatidic acid] results in increased phosphorylation of PTK2 protein; KNG1 protein inhibits the reaction [[wortmannin co-treated with lysophosphatidic acid] results in increased phosphorylation of PTK2 protein] [wortmannin co-treated with lysophosphatidic acid] results in increased phosphorylation of PTK2 protein; Atropine inhibits the reaction [oxotremorine M inhibits the reaction [[wortmannin co-treated with lysophosphatidic acid] results in increased phosphorylation of PTK2 protein]]; oxotremorine M inhibits the reaction [[wortmannin co-treated with lysophosphatidic acid] results in increased phosphorylation of PTK2 protein] |
CTD |
PMID:10537051 PMID:11792571 |
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NCBI chr 7:105,126,725...105,331,848
Ensembl chr 7:105,126,728...105,331,783
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G |
Ptk2b |
protein tyrosine kinase 2 beta |
increases phosphorylation |
ISO |
lysophosphatidic acid results in increased phosphorylation of PTK2B protein |
CTD |
PMID:11792571 |
|
NCBI chr15:40,360,722...40,481,235
Ensembl chr15:40,360,723...40,481,282
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G |
Rhoa |
ras homolog family member A |
increases activity multiple interactions |
EXP ISO |
lysophosphatidic acid results in increased activity of RHOA protein Farnesol analog inhibits the reaction [lysophosphatidic acid results in increased activity of RHOA protein]; geranylgeraniol analog inhibits the reaction [lysophosphatidic acid results in increased activity of RHOA protein] |
CTD |
PMID:15081308 PMID:24587105 |
|
NCBI chr 8:108,991,926...109,025,746
Ensembl chr 8:108,991,954...109,025,746
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G |
Rhoc |
ras homolog family member C |
multiple interactions increases activity |
ISO |
Farnesol analog inhibits the reaction [lysophosphatidic acid results in increased activity of RHOC protein]; geranylgeraniol analog inhibits the reaction [lysophosphatidic acid results in increased activity of RHOC protein] |
CTD |
PMID:24587105 |
|
NCBI chr 2:192,287,065...192,293,292
Ensembl chr 2:192,287,130...192,295,306
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G |
Rps6kb1 |
ribosomal protein S6 kinase B1 |
increases phosphorylation multiple interactions |
ISO EXP |
lysophosphatidic acid results in increased phosphorylation of RPS6KB1 protein resveratrol inhibits the reaction [lysophosphatidic acid results in increased phosphorylation of RPS6KB1 protein] 1-Butanol inhibits the reaction [lysophosphatidic acid results in increased phosphorylation of RPS6KB1 protein]; 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [lysophosphatidic acid results in increased phosphorylation of RPS6KB1 protein]; exoenzyme C3, Clostridium botulinum inhibits the reaction [lysophosphatidic acid results in increased phosphorylation of RPS6KB1 protein] |
CTD |
PMID:14769825 PMID:17919812 |
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NCBI chr10:71,323,777...71,367,908
Ensembl chr10:71,323,777...71,367,908
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G |
Tfrc |
transferrin receptor |
multiple interactions |
ISO |
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [[lysophosphatidic acid co-treated with KITLG protein co-treated with EPO protein] results in increased expression of TFRC protein]; [lysophosphatidic acid co-treated with KITLG protein co-treated with EPO protein] results in increased expression of TFRC mRNA; [lysophosphatidic acid co-treated with KITLG protein co-treated with EPO protein] results in increased expression of TFRC protein; lysophosphatidic acid promotes the reaction [[KITLG protein co-treated with EPO protein] results in increased expression of TFRC mRNA]; lysophosphatidic acid promotes the reaction [[KITLG protein co-treated with EPO protein] results in increased expression of TFRC protein]; Quercetin inhibits the reaction [[lysophosphatidic acid co-treated with KITLG protein co-treated with EPO protein] results in increased expression of TFRC mRNA]; Quercetin inhibits the reaction [[lysophosphatidic acid co-treated with KITLG protein co-treated with EPO protein] results in increased expression of TFRC protein]; WP1066 inhibits the reaction [[lysophosphatidic acid co-treated with KITLG protein co-treated with EPO protein] results in increased expression of TFRC protein] |
CTD |
PMID:21915944 |
|
NCBI chr11:68,163,413...68,185,257
Ensembl chr11:68,163,413...68,185,257
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G |
Timp1 |
TIMP metallopeptidase inhibitor 1 |
multiple interactions increases expression |
ISO |
3-(4-(4-((1-(2-chlorophenyl)ethoxy)carbonyl amino)-3-methyl-5-isoxazolyl) benzylsulfanyl) propanoic acid inhibits the reaction [lysophosphatidic acid results in increased expression of TIMP1 protein] |
CTD |
PMID:25822713 |
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NCBI chr X:1,212,969...1,217,714
Ensembl chr X:1,212,972...1,217,664
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G |
Tnf |
tumor necrosis factor |
multiple interactions |
ISO |
TNF protein inhibits the reaction [lysophosphatidic acid results in decreased expression of ENPP2 protein] |
CTD |
PMID:25896349 |
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NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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G |
Vegfa |
vascular endothelial growth factor A |
increases expression multiple interactions |
ISO |
[lysophosphatidic acid results in increased expression of HIF1A protein] which results in increased expression of VEGFA mRNA; [lysophosphatidic acid results in increased expression of HIF1A protein] which results in increased expression of VEGFA protein resveratrol inhibits the reaction [lysophosphatidic acid results in increased expression of VEGFA protein] |
CTD |
PMID:17919812 |
|
NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
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G |
Lipc |
lipase C, hepatic type |
multiple interactions decreases abundance |
ISO |
[LIPC gene mutant form co-treated with LIPG gene mutant form] results in decreased abundance of 1-stearoyl-2-oleoyl-sn-glycerol LIPC gene mutant form results in decreased abundance of 1-stearoyl-2-oleoyl-sn-glycerol |
CTD |
PMID:24777581 |
|
NCBI chr 8:71,509,633...71,635,663
Ensembl chr 8:71,509,635...71,635,464
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G |
Lipg |
lipase G, endothelial type |
decreases abundance multiple interactions |
ISO |
LIPG gene mutant form results in decreased abundance of 1-stearoyl-2-oleoyl-sn-glycerol [LIPC gene mutant form co-treated with LIPG gene mutant form] results in decreased abundance of 1-stearoyl-2-oleoyl-sn-glycerol |
CTD |
PMID:24777581 |
|
NCBI chr18:68,514,923...68,536,105
Ensembl chr18:68,514,923...68,536,260
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G |
Lipc |
lipase C, hepatic type |
decreases abundance |
ISO |
LIPC gene mutant form results in decreased abundance of 1-palmitoyl-2-oleoyl-sn-glycerol |
CTD |
PMID:24777581 |
|
NCBI chr 8:71,509,633...71,635,663
Ensembl chr 8:71,509,635...71,635,464
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G |
Lipg |
lipase G, endothelial type |
decreases abundance |
ISO |
LIPG gene mutant form results in decreased abundance of 1-palmitoyl-2-oleoyl-sn-glycerol |
CTD |
PMID:24777581 |
|
NCBI chr18:68,514,923...68,536,105
Ensembl chr18:68,514,923...68,536,260
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G |
Fabp1 |
fatty acid binding protein 1 |
affects abundance |
ISO |
FABP1 protein affects the abundance of 2-oleoylglycerol |
CTD |
PMID:29414765 |
|
NCBI chr 4:103,191,015...103,194,791
Ensembl chr 4:103,191,006...103,194,788
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G |
Mgll |
monoglyceride lipase |
increases degradation multiple interactions |
EXP |
MGLL protein results in increased degradation of 2-oleoylglycerol Nitroglycerin promotes the reaction [MGLL protein results in increased degradation of 2-oleoylglycerol] |
CTD |
PMID:19515121 |
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NCBI chr 4:121,192,186...121,294,187
Ensembl chr 4:121,192,195...121,294,179
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G |
Ephx3 |
epoxide hydrolase 3 |
multiple interactions |
ISO |
[EPHX3 gene mutant form results in decreased hydrolysis of Epoxy Compounds] results in decreased abundance of [9,10,13-trihydroxy-11-octadecenoic acid binds to Ceramides]; [EPHX3 gene mutant form results in decreased hydrolysis of Epoxy Compounds] which results in decreased chemical synthesis of 9,10,13-trihydroxy-11-octadecenoic acid |
CTD |
PMID:33334892 |
|
NCBI chr 7:11,206,812...11,212,122
Ensembl chr 7:11,206,812...11,212,122
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G |
Pafah1b1 |
platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 |
increases expression multiple interactions |
EXP |
Castor Oil results in increased expression of PAFAH1B1 protein isosorbide-5-mononitrate inhibits the reaction [Castor Oil results in increased expression of PAFAH1B1 protein] |
CTD |
PMID:1354728 PMID:2743081 PMID:8738301 |
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NCBI chr10:59,533,042...59,591,808
Ensembl chr10:59,534,117...59,591,808
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G |
Lipc |
lipase C, hepatic type |
multiple interactions |
ISO |
[LIPC gene mutant form co-treated with LIPG gene mutant form] results in increased abundance of cholesteryl oleate |
CTD |
PMID:24777581 |
|
NCBI chr 8:71,509,633...71,635,663
Ensembl chr 8:71,509,635...71,635,464
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G |
Lipg |
lipase G, endothelial type |
multiple interactions increases abundance |
ISO |
[LIPC gene mutant form co-treated with LIPG gene mutant form] results in increased abundance of cholesteryl oleate LIPG gene mutant form results in increased abundance of cholesteryl oleate |
CTD |
PMID:24777581 |
|
NCBI chr18:68,514,923...68,536,105
Ensembl chr18:68,514,923...68,536,260
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G |
Abcg8 |
ATP binding cassette subfamily G member 8 |
affects expression |
EXP |
Corn Oil affects the expression of ABCG8 mRNA |
CTD |
PMID:16360708 |
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NCBI chr 6:9,945,629...9,964,912
Ensembl chr 6:9,945,629...9,964,912
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G |
Acaca |
acetyl-CoA carboxylase alpha |
increases expression |
EXP |
Corn Oil results in increased expression of ACACA mRNA |
CTD |
PMID:1973097 |
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NCBI chr10:69,014,261...69,276,453
Ensembl chr10:69,014,170...69,276,457
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G |
Acly |
ATP citrate lyase |
affects expression |
EXP |
Corn Oil affects the expression of ACLY mRNA |
CTD |
PMID:16360708 |
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NCBI chr10:85,412,045...85,464,253
Ensembl chr10:85,412,049...85,463,320
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G |
Acot2 |
acyl-CoA thioesterase 2 |
affects expression |
EXP |
Corn Oil affects the expression of ACOT2 mRNA |
CTD |
PMID:16360708 |
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NCBI chr 6:103,611,738...103,619,404
Ensembl chr 6:103,611,544...103,619,245
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G |
Adipoq |
adiponectin, C1Q and collagen domain containing |
multiple interactions |
EXP |
Corn Oil promotes the reaction [Glucose results in increased expression of ADIPOQ protein] |
CTD |
PMID:29165388 |
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NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564
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G |
Akr1b7 |
aldo-keto reductase family 1, member B7 |
affects expression |
EXP |
Corn Oil affects the expression of AKR1B7 mRNA |
CTD |
PMID:16360708 |
|
NCBI chr 4:63,053,560...63,100,934
Ensembl chr 4:63,076,800...63,089,502
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G |
Aldh1a1 |
aldehyde dehydrogenase 1 family, member A1 |
affects expression |
EXP |
Corn Oil affects the expression of ALDH1A1 mRNA |
CTD |
PMID:16360708 |
|
NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961
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G |
Angptl4 |
angiopoietin-like 4 |
affects expression |
EXP |
Corn Oil affects the expression of ANGPTL4 mRNA |
CTD |
PMID:16360708 |
|
NCBI chr 7:14,550,288...14,557,797
Ensembl chr 7:14,550,311...14,556,519
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G |
Areg |
amphiregulin |
multiple interactions |
ISO |
[Estradiol co-treated with Progesterone co-treated with Corn Oil] results in increased expression of AREG mRNA |
CTD |
PMID:32186404 |
|
NCBI chr14:16,972,185...16,981,443
Ensembl chr14:16,972,187...16,981,535
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G |
Bad |
BCL2-associated agonist of cell death |
increases expression |
EXP |
Corn Oil results in increased expression of BAD mRNA |
CTD |
PMID:22760963 |
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NCBI chr 1:204,133,502...204,142,829
Ensembl chr 1:204,131,501...204,142,823
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G |
Bdkrb1 |
bradykinin receptor B1 |
multiple interactions |
EXP |
Corn Oil inhibits the reaction [Glucose results in increased expression of BDKRB1 protein] |
CTD |
PMID:29165388 |
|
NCBI chr 6:124,510,827...124,514,475
Ensembl chr 6:124,510,870...124,513,747
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G |
Bhlhe40 |
basic helix-loop-helix family, member e40 |
affects expression |
EXP |
Corn Oil affects the expression of BHLHE40 mRNA |
CTD |
PMID:16360708 |
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NCBI chr 4:141,618,453...141,624,154
Ensembl chr 4:141,618,476...141,624,774
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G |
Bhmt |
betaine-homocysteine S-methyltransferase |
affects expression |
EXP |
Corn Oil affects the expression of BHMT mRNA |
CTD |
PMID:16360708 |
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NCBI chr 2:24,859,871...24,879,449
Ensembl chr 2:24,859,873...24,879,742
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G |
Birc3 |
baculoviral IAP repeat-containing 3 |
increases expression |
ISO |
Corn Oil results in increased expression of BIRC3 mRNA |
CTD |
PMID:33263755 |
|
NCBI chr 8:5,000,844...5,028,470
Ensembl chr 8:5,000,845...5,015,802
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G |
Bmp1 |
bone morphogenetic protein 1 |
affects expression |
EXP |
Corn Oil affects the expression of BMP1 mRNA |
CTD |
PMID:16360708 |
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NCBI chr15:45,551,603...45,595,862
Ensembl chr15:45,551,603...45,595,776
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G |
Bmp2 |
bone morphogenetic protein 2 |
multiple interactions |
ISO |
[Estradiol co-treated with Progesterone co-treated with Corn Oil] results in increased expression of BMP2 mRNA |
CTD |
PMID:32186404 |
|
NCBI chr 3:120,812,660...120,822,579
Ensembl chr 3:120,812,882...120,821,397
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G |
Cadm1 |
cell adhesion molecule 1 |
affects expression |
EXP |
Corn Oil affects the expression of CADM1 mRNA |
CTD |
PMID:16360708 |
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NCBI chr 8:47,847,836...48,178,703
Ensembl chr 8:47,847,325...48,182,833
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G |
Calca |
calcitonin-related polypeptide alpha |
multiple interactions |
ISO |
[Estradiol co-treated with Progesterone co-treated with Corn Oil] results in increased expression of CALCA mRNA |
CTD |
PMID:32186404 |
|
NCBI chr 1:168,878,212...168,883,176
Ensembl chr 1:168,878,214...168,883,105
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G |
Car6 |
carbonic anhydrase 6 |
increases expression |
ISO |
Corn Oil results in increased expression of CAR6 mRNA |
CTD |
PMID:33263755 |
|
NCBI chr 5:160,658,104...160,676,644
Ensembl chr 5:160,658,105...160,676,644
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G |
Card9 |
caspase recruitment domain family, member 9 |
increases expression |
ISO |
Corn Oil results in increased expression of CARD9 mRNA |
CTD |
PMID:33263755 |
|
NCBI chr 3:9,171,814...9,180,310
Ensembl chr 3:9,171,815...9,180,237
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G |
Cat |
catalase |
multiple interactions decreases expression |
ISO |
[bisphenol A co-treated with Resveratrol co-treated with Corn Oil] results in decreased expression of CAT protein Corn Oil results in decreased expression of CAT protein |
CTD |
PMID:36432690 |
|
NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
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G |
Cav3 |
caveolin 3 |
decreases expression |
ISO |
Corn Oil results in decreased expression of CAV3 mRNA |
CTD |
PMID:33263755 |
|
NCBI chr 4:145,582,168...145,598,142
Ensembl chr 4:145,582,060...145,598,137
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G |
Ccl3 |
C-C motif chemokine ligand 3 |
increases expression decreases expression |
ISO EXP |
Corn Oil results in increased expression of CCL3 mRNA Corn Oil results in decreased expression of CCL3 mRNA |
CTD |
PMID:22760963 PMID:23409006 |
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NCBI chr10:68,451,388...68,452,938
Ensembl chr10:68,451,388...68,452,938
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G |
Ccnd1 |
cyclin D1 |
affects expression |
EXP |
Corn Oil affects the expression of CCND1 mRNA |
CTD |
PMID:16360708 |
|
NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
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G |
Cd36 |
CD36 molecule |
decreases expression |
EXP |
Corn Oil results in decreased expression of CD36 mRNA |
CTD |
PMID:22760963 |
|
NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903
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G |
Cdhr1 |
cadherin-related family member 1 |
increases expression |
EXP |
Corn Oil results in increased expression of CDHR1 mRNA |
CTD |
PMID:22760963 |
|
NCBI chr16:12,843,436...12,863,321
Ensembl chr16:12,843,437...12,863,396
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G |
Cdkn1a |
cyclin-dependent kinase inhibitor 1A |
affects expression increases expression |
EXP |
Corn Oil affects the expression of CDKN1A mRNA Corn Oil results in increased expression of CDKN1A mRNA |
CTD |
PMID:16360708 PMID:22760963 |
|
NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
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G |
Cenpt |
centromere protein T |
increases expression |
EXP |
Corn Oil results in increased expression of CENPT mRNA |
CTD |
PMID:22760963 |
|
NCBI chr19:33,734,684...33,741,159
Ensembl chr19:33,734,685...33,741,142
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G |
Cfb |
complement factor B |
increases expression |
EXP |
Corn Oil results in increased expression of CFB mRNA |
CTD |
PMID:22760963 |
|
NCBI chr20:3,970,643...3,976,510
Ensembl chr20:3,951,474...3,976,505
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G |
Cldn1 |
claudin 1 |
decreases expression |
ISO |
Corn Oil results in decreased expression of CLDN1 mRNA |
CTD |
PMID:33263755 |
|
NCBI chr11:74,421,569...74,436,728
Ensembl chr11:74,421,569...74,436,724
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G |
Cldn9 |
claudin 9 |
increases expression |
ISO |
Corn Oil results in increased expression of CLDN9 mRNA |
CTD |
PMID:33263755 |
|
NCBI chr10:12,714,137...12,715,568
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|
G |
Cox7a1 |
cytochrome c oxidase subunit 7A1 |
decreases expression |
ISO |
Corn Oil results in decreased expression of COX7A1 mRNA |
CTD |
PMID:23409006 |
|
NCBI chr 1:85,422,162...85,447,530
Ensembl chr 1:85,441,871...85,445,151
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G |
Cpt1a |
carnitine palmitoyltransferase 1A |
increases expression multiple interactions affects expression |
EXP ISO |
Corn Oil results in increased expression of CPT1A mRNA [bisphenol A co-treated with Resveratrol co-treated with Corn Oil] results in increased expression of CPT1A mRNA Corn Oil affects the expression of CPT1A mRNA |
CTD |
PMID:16360708 PMID:22760963 PMID:36432690 |
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NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055
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G |
Cpt2 |
carnitine palmitoyltransferase 2 |
multiple interactions |
ISO |
[bisphenol A co-treated with Resveratrol co-treated with Corn Oil] results in increased expression of CPT2 mRNA |
CTD |
PMID:36432690 |
|
NCBI chr 5:122,664,677...122,682,126
Ensembl chr 5:122,664,677...122,682,095
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G |
Crot |
carnitine O-octanoyltransferase |
affects expression multiple interactions |
EXP ISO |
Corn Oil affects the expression of CROT mRNA [bisphenol A co-treated with Resveratrol co-treated with Corn Oil] results in increased expression of CROT mRNA |
CTD |
PMID:16360708 PMID:36432690 |
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NCBI chr 4:25,068,270...25,133,111
Ensembl chr 4:25,080,587...25,133,109
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G |
Ctsg |
cathepsin G |
increases expression |
EXP |
Corn Oil results in increased expression of CTSG mRNA |
CTD |
PMID:22760963 |
|
NCBI chr15:29,930,988...29,937,353
Ensembl chr15:29,931,003...29,937,353
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G |
Cyp17a1 |
cytochrome P450, family 17, subfamily a, polypeptide 1 |
affects expression |
EXP |
Corn Oil affects the expression of CYP17A1 mRNA |
CTD |
PMID:16360708 |
|
NCBI chr 1:245,535,462...245,543,148
Ensembl chr 1:245,535,462...245,541,573
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G |
Cyp7a1 |
cytochrome P450 family 7 subfamily A member 1 |
affects expression |
EXP |
Corn Oil affects the expression of CYP7A1 mRNA |
CTD |
PMID:16360708 |
|
NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688
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G |
Cyp8b1 |
cytochrome P450 family 8 subfamily B member 1 |
affects expression |
EXP |
Corn Oil affects the expression of CYP8B1 mRNA |
CTD |
PMID:16360708 |
|
NCBI chr 8:121,578,123...121,580,093
Ensembl chr 8:121,557,062...121,580,166
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G |
Ephx2 |
epoxide hydrolase 2 |
affects expression |
EXP |
Corn Oil affects the expression of EPHX2 mRNA |
CTD |
PMID:16360708 |
|
NCBI chr15:40,289,901...40,327,632
Ensembl chr15:40,289,902...40,327,615
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G |
Ets1 |
ETS proto-oncogene 1, transcription factor |
decreases expression |
EXP |
Corn Oil results in decreased expression of ETS1 mRNA |
CTD |
PMID:22760963 |
|
NCBI chr 8:31,045,909...31,168,010
Ensembl chr 8:31,045,945...31,168,010
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G |
Fabp1 |
fatty acid binding protein 1 |
multiple interactions |
EXP |
[Ethanol co-treated with Corn Oil] results in decreased expression of FABP1 mRNA |
CTD |
PMID:15016835 |
|
NCBI chr 4:103,191,015...103,194,791
Ensembl chr 4:103,191,006...103,194,788
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G |
Fabp2 |
fatty acid binding protein 2 |
affects expression |
EXP |
Corn Oil affects the expression of FABP2 mRNA |
CTD |
PMID:16360708 |
|
NCBI chr 2:211,040,032...211,044,089
Ensembl chr 2:211,040,032...211,044,089
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G |
Fabp7 |
fatty acid binding protein 7 |
affects expression |
EXP |
Corn Oil affects the expression of FABP7 mRNA |
CTD |
PMID:16360708 |
|
NCBI chr20:37,123,193...37,126,725
Ensembl chr20:37,123,193...37,126,880
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G |
Fasn |
fatty acid synthase |
affects expression |
EXP |
Corn Oil affects the expression of FASN mRNA |
CTD |
PMID:16360708 |
|
NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261
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G |
Fcgrt |
Fc gamma receptor and transporter |
decreases expression |
EXP |
Corn Oil results in decreased expression of FCGRT mRNA |
CTD |
PMID:22760963 |
|
NCBI chr 1:95,574,436...95,584,171
Ensembl chr 1:95,567,175...95,584,084
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G |
Fgb |
fibrinogen beta chain |
affects expression |
EXP |
Corn Oil affects the expression of FGB mRNA |
CTD |
PMID:16360708 |
|
NCBI chr 2:168,394,901...168,402,863
Ensembl chr 2:168,394,916...168,405,979
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G |
Fgf21 |
fibroblast growth factor 21 |
affects expression |
EXP |
Corn Oil affects the expression of FGF21 mRNA |
CTD |
PMID:16360708 |
|
NCBI chr 1:96,083,360...96,084,911
Ensembl chr 1:96,083,441...96,090,454
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G |
Fst |
follistatin |
multiple interactions |
ISO |
[Estradiol co-treated with Progesterone co-treated with Corn Oil] results in increased expression of FST mRNA |
CTD |
PMID:32186404 |
|
NCBI chr 2:46,123,260...46,130,584
Ensembl chr 2:46,123,439...46,130,571
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G |
G0s2 |
G0/G1switch 2 |
affects expression |
EXP |
Corn Oil affects the expression of G0S2 mRNA |
CTD |
PMID:16360708 |
|
NCBI chr13:104,806,351...104,807,263
Ensembl chr13:104,806,156...104,807,451
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G |
Gadd45a |
growth arrest and DNA-damage-inducible, alpha |
affects expression |
EXP |
Corn Oil affects the expression of GADD45A mRNA |
CTD |
PMID:16360708 |
|
NCBI chr 4:96,154,789...96,157,091
Ensembl chr 4:96,154,789...96,157,115
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G |
Gal |
galanin and GMAP prepropeptide |
increases expression |
EXP |
Corn Oil results in increased expression of GAL mRNA |
CTD |
PMID:22760963 |
|
NCBI chr 1:200,650,439...200,655,302
Ensembl chr 1:200,650,439...200,654,959
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G |
Gck |
glucokinase |
affects expression |
EXP |
Corn Oil affects the expression of GCK mRNA |
CTD |
PMID:16360708 |
|
NCBI chr14:80,785,060...80,829,842
Ensembl chr14:80,785,060...80,826,995
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G |
Gjd2 |
gap junction protein, delta 2 |
increases expression |
ISO |
Corn Oil results in increased expression of GJD2 mRNA |
CTD |
PMID:33263755 |
|
NCBI chr 3:100,771,450...100,776,134
Ensembl chr 3:100,772,062...100,775,061
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G |
Got1 |
glutamic-oxaloacetic transaminase 1 |
affects expression |
EXP |
Corn Oil affects the expression of GOT1 mRNA |
CTD |
PMID:16360708 |
|
NCBI chr 1:242,357,293...242,381,535
Ensembl chr 1:242,357,306...242,380,633
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G |
Got2 |
glutamic-oxaloacetic transaminase 2 |
decreases expression |
EXP |
Corn Oil results in decreased expression of GOT2 mRNA |
CTD |
PMID:34987138 |
|
NCBI chr19:9,174,304...9,199,995
Ensembl chr19:9,174,311...9,199,994
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G |
Gpd2 |
glycerol-3-phosphate dehydrogenase 2 |
affects expression |
EXP |
Corn Oil affects the expression of GPD2 mRNA |
CTD |
PMID:16360708 |
|
NCBI chr 3:41,800,552...41,937,729
Ensembl chr 3:41,801,930...41,936,901
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G |
Gpt |
glutamic--pyruvic transaminase |
multiple interactions |
EXP |
[Corn Oil co-treated with (5'-(4-amino-7,7-dimethyl-2-trifluoromethyl-7H-pyrimido(4,5-b)(1,4)oxazin-6-yl)-2',3'-dihydrospiro(cyclohexane-1,1'-inden)-4-yl)acetic acid] results in increased activity of GPT protein; Dactinomycin inhibits the reaction [[Corn Oil co-treated with (5'-(4-amino-7,7-dimethyl-2-trifluoromethyl-7H-pyrimido(4,5-b)(1,4)oxazin-6-yl)-2',3'-dihydrospiro(cyclohexane-1,1'-inden)-4-yl)acetic acid] results in increased activity of GPT protein]; Orlistat inhibits the reaction [[Corn Oil co-treated with (5'-(4-amino-7,7-dimethyl-2-trifluoromethyl-7H-pyrimido(4,5-b)(1,4)oxazin-6-yl)-2',3'-dihydrospiro(cyclohexane-1,1'-inden)-4-yl)acetic acid] results in increased activity of GPT protein] |
CTD |
PMID:29479035 |
|
NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
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G |
H2ac25 |
H2A clustered histone 25 |
affects expression |
EXP |
Corn Oil affects the expression of H2A mRNA |
CTD |
PMID:16360708 |
|
NCBI chr10:43,733,702...43,735,254
Ensembl chr10:43,733,668...43,744,874
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G |
Hal |
histidine ammonia lyase |
affects expression |
EXP |
Corn Oil affects the expression of HAL mRNA |
CTD |
PMID:16360708 |
|
NCBI chr 7:28,007,449...28,037,701
Ensembl chr 7:28,006,972...28,037,701
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G |
Hamp |
hepcidin antimicrobial peptide |
affects expression |
EXP |
Corn Oil affects the expression of HAMP mRNA |
CTD |
PMID:16360708 |
|
NCBI chr 1:86,170,926...86,172,865
Ensembl chr 1:86,170,901...86,172,891
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G |
Hmgcr |
3-hydroxy-3-methylglutaryl-CoA reductase |
affects expression |
EXP |
Corn Oil affects the expression of HMGCR mRNA |
CTD |
PMID:16360708 |
|
NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703
|
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G |
Hoxa11 |
homeobox A11 |
multiple interactions |
ISO |
[Estradiol co-treated with Progesterone co-treated with Corn Oil] results in increased expression of HOXA11 mRNA |
CTD |
PMID:32186404 |
|
NCBI chr 4:81,342,527...81,346,189
Ensembl chr 4:81,342,528...81,346,232
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G |
Hp |
haptoglobin |
increases expression |
EXP |
Corn Oil results in increased expression of HP mRNA |
CTD |
PMID:22760963 |
|
NCBI chr19:37,539,626...37,544,178
Ensembl chr19:37,539,627...37,544,523
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G |
Hsp90aa1 |
heat shock protein 90 alpha family class A member 1 |
increases expression |
ISO |
Corn Oil results in increased expression of HSP90AA1 mRNA |
CTD |
PMID:33263755 |
|
NCBI chr 6:129,702,376...129,707,907
Ensembl chr 6:129,702,383...129,707,268
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G |
Idi1 |
isopentenyl-diphosphate delta isomerase 1 |
affects expression |
EXP |
Corn Oil affects the expression of IDI1 mRNA |
CTD |
PMID:16360708 |
|
NCBI chr17:61,629,592...61,637,357
Ensembl chr17:61,629,594...61,637,357
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G |
Igf2bp2 |
insulin-like growth factor 2 mRNA binding protein 2 |
affects expression increases expression |
EXP |
Corn Oil affects the expression of IGF2BP2 mRNA Corn Oil results in increased expression of IGF2BP2 mRNA |
CTD |
PMID:22760963 |
|
NCBI chr11:78,874,402...78,974,392
Ensembl chr11:78,874,414...78,974,377
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G |
Igfbp1 |
insulin-like growth factor binding protein 1 |
affects expression |
EXP |
Corn Oil affects the expression of IGFBP1 mRNA |
CTD |
PMID:16360708 |
|
NCBI chr14:82,047,415...82,052,482
Ensembl chr14:82,047,415...82,052,482
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G |
Ihh |
Indian hedgehog signaling molecule |
multiple interactions |
ISO |
[Estradiol co-treated with Progesterone co-treated with Corn Oil] results in increased expression of IHH mRNA |
CTD |
PMID:32186404 |
|
NCBI chr 9:76,504,315...76,510,532
Ensembl chr 9:76,504,315...76,510,532
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G |
Il12b |
interleukin 12B |
increases secretion |
EXP |
Corn Oil results in increased secretion of IL12B protein |
CTD |
PMID:33263755 |
|
NCBI chr10:28,888,832...28,903,802
Ensembl chr10:28,893,008...28,902,903
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G |
Il18 |
interleukin 18 |
increases expression |
ISO |
Corn Oil results in increased expression of IL18 mRNA |
CTD |
PMID:33263755 |
|
NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887
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G |
Il1a |
interleukin 1 alpha |
increases secretion |
EXP |
Corn Oil results in increased secretion of IL1A protein |
CTD |
PMID:33263755 |
|
NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
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G |
Il1b |
interleukin 1 beta |
increases secretion |
EXP |
Corn Oil results in increased secretion of IL1B protein |
CTD |
PMID:33263755 |
|
NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
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G |
Il1rn |
interleukin 1 receptor antagonist |
increases expression |
EXP |
Corn Oil results in increased expression of IL1RN mRNA |
CTD |
PMID:22760963 |
|
NCBI chr 3:7,111,567...7,127,451
Ensembl chr 3:7,111,550...7,127,445
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G |
Il4 |
interleukin 4 |
increases expression increases secretion decreases expression |
ISO EXP |
Corn Oil results in increased expression of IL4 mRNA Corn Oil results in increased secretion of IL4 protein Corn Oil results in decreased expression of IL4 mRNA |
CTD |
PMID:23409006 PMID:33263755 |
|
NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
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G |
Il6r |
interleukin 6 receptor |
increases expression |
EXP |
Corn Oil results in increased expression of IL6R mRNA |
CTD |
PMID:22760963 |
|
NCBI chr 2:175,289,157...175,347,719
Ensembl chr 2:175,298,686...175,347,536
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G |
Il9 |
interleukin 9 |
increases secretion |
EXP |
Corn Oil results in increased secretion of IL9 protein |
CTD |
PMID:33263755 |
|
NCBI chr17:8,111,772...8,114,895
Ensembl chr17:8,111,772...8,114,895
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G |
Inhbe |
inhibin subunit beta E |
affects expression |
EXP |
Corn Oil affects the expression of INHBE mRNA |
CTD |
PMID:16360708 |
|
NCBI chr 7:63,176,221...63,179,209
Ensembl chr 7:63,176,219...63,179,172
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G |
Ins1 |
insulin 1 |
multiple interactions |
EXP |
Corn Oil inhibits the reaction [Glucose results in increased expression of INS1 protein] |
CTD |
PMID:29165388 |
|
NCBI chr 1:251,244,973...251,245,540
Ensembl chr 1:251,244,973...251,245,536
|
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G |
Irak1 |
interleukin-1 receptor-associated kinase 1 |
increases expression |
ISO |
Corn Oil results in increased expression of IRAK1 mRNA |
CTD |
PMID:33263755 |
|
NCBI chr X:151,768,621...151,778,521
Ensembl chr X:151,768,777...151,778,521
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G |
Irf5 |
interferon regulatory factor 5 |
increases expression |
ISO |
Corn Oil results in increased expression of IRF5 mRNA |
CTD |
PMID:33263755 |
|
NCBI chr 4:58,127,577...58,140,665
Ensembl chr 4:58,127,640...58,139,267
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G |
Irf7 |
interferon regulatory factor 7 |
increases expression |
ISO |
Corn Oil results in increased expression of IRF7 mRNA |
CTD |
PMID:33263755 |
|
NCBI chr 1:196,367,380...196,370,943
Ensembl chr 1:196,367,361...196,370,832
|
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G |
Jun |
Jun proto-oncogene, AP-1 transcription factor subunit |
increases expression |
ISO |
Corn Oil results in increased expression of JUN mRNA |
CTD |
PMID:33263755 |
|
NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
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G |
Klf2 |
KLF transcription factor 2 |
affects expression |
EXP |
Corn Oil affects the expression of KLF2 mRNA |
CTD |
PMID:16360708 |
|
NCBI chr16:17,521,107...17,523,739
Ensembl chr16:17,514,552...17,523,944
|
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G |
Lcat |
lecithin cholesterol acyltransferase |
multiple interactions |
ISO |
[bisphenol A co-treated with Resveratrol co-treated with Corn Oil] results in increased expression of LCAT mRNA |
CTD |
PMID:36432690 |
|
NCBI chr19:33,834,748...33,838,214
Ensembl chr19:33,834,403...33,838,231
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G |
Lcn2 |
lipocalin 2 |
increases expression |
EXP |
Corn Oil results in increased expression of LCN2 mRNA |
CTD |
PMID:22760963 |
|
NCBI chr 3:15,680,688...15,684,033
Ensembl chr 3:15,680,687...15,684,095
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G |
Lep |
leptin |
multiple interactions |
EXP |
Corn Oil inhibits the reaction [Glucose results in increased expression of LEP protein] |
CTD |
PMID:29165388 |
|
NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
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G |
Lgals1 |
galectin 1 |
increases expression |
EXP |
Corn Oil results in increased expression of LGALS1 mRNA |
CTD |
PMID:22760963 |
|
NCBI chr 7:110,485,239...110,488,345
Ensembl chr 7:110,481,392...110,488,345
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G |
Lox |
lysyl oxidase |
multiple interactions |
ISO |
Corn Oil results in increased activity of and results in increased cleavage of LOX protein |
CTD |
PMID:26240151 |
|
NCBI chr18:45,964,544...45,977,431
Ensembl chr18:45,967,343...46,041,477
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G |
Ly75 |
lymphocyte antigen 75 |
increases expression |
EXP |
Corn Oil results in increased expression of LY75 mRNA |
CTD |
PMID:22760963 |
|
NCBI chr 3:44,764,702...44,852,219
Ensembl chr 3:44,765,122...44,852,374
|
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G |
Map2k1 |
mitogen activated protein kinase kinase 1 |
increases expression |
ISO |
Corn Oil results in increased expression of MAP2K1 mRNA |
CTD |
PMID:33263755 |
|
NCBI chr 8:64,683,449...64,754,900
Ensembl chr 8:64,683,449...64,755,147
|
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G |
Map2k3 |
mitogen activated protein kinase kinase 3 |
increases expression |
ISO |
Corn Oil results in increased expression of MAP2K3 mRNA |
CTD |
PMID:33263755 |
|
NCBI chr10:45,608,145...45,629,492
Ensembl chr10:45,607,163...45,629,492
|
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G |
Map2k6 |
mitogen-activated protein kinase kinase 6 |
affects expression |
EXP |
Corn Oil affects the expression of MAP2K6 mRNA |
CTD |
PMID:16360708 |
|
NCBI chr10:95,373,304...95,490,406
Ensembl chr10:95,373,204...95,488,293
|
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G |
Map3k7 |
mitogen activated protein kinase kinase kinase 7 |
increases expression |
ISO |
Corn Oil results in increased expression of MAP3K7 mRNA |
CTD |
PMID:33263755 |
|
NCBI chr 5:46,356,973...46,415,597
Ensembl chr 5:46,357,931...46,415,597
|
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G |
Mapk1 |
mitogen activated protein kinase 1 |
increases expression |
ISO |
Corn Oil results in increased expression of MAPK1 mRNA |
CTD |
PMID:33263755 |
|
NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
|
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G |
Mapk14 |
mitogen activated protein kinase 14 |
increases expression |
ISO |
Corn Oil results in increased expression of MAPK14 mRNA |
CTD |
PMID:33263755 |
|
NCBI chr20:6,749,646...6,810,590
Ensembl chr20:6,749,670...6,810,589
|
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G |
Mapk3 |
mitogen activated protein kinase 3 |
increases expression |
ISO |
Corn Oil results in increased expression of MAPK3 mRNA |
CTD |
PMID:33263755 |
|
NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
|
|
G |
Mdm2 |
MDM2 proto-oncogene |
decreases expression |
EXP |
Corn Oil results in decreased expression of MDM2 mRNA |
CTD |
PMID:22760963 |
|
NCBI chr 7:53,290,660...53,315,205
Ensembl chr 7:53,290,664...53,314,915
|
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G |
Mgmt |
O-6-methylguanine-DNA methyltransferase |
increases expression |
EXP |
Corn Oil results in increased expression of MGMT mRNA |
CTD |
PMID:22760963 |
|
NCBI chr 1:191,710,980...191,937,760
Ensembl chr 1:191,710,930...191,937,756
|
|
G |
Mgst2 |
microsomal glutathione S-transferase 2 |
increases expression |
EXP |
Corn Oil results in increased expression of MGST2 mRNA |
CTD |
PMID:22760963 |
|
NCBI chr 2:135,679,524...135,715,828
Ensembl chr 2:135,693,557...135,715,828
|
|
G |
Mlycd |
malonyl-CoA decarboxylase |
decreases expression |
EXP |
Corn Oil results in decreased expression of MLYCD mRNA |
CTD |
PMID:22760963 |
|
NCBI chr19:47,447,931...47,463,794
Ensembl chr19:47,447,970...47,463,793
|
|
G |
Msmo1 |
methylsterol monooxygenase 1 |
affects expression |
EXP |
Corn Oil affects the expression of MSMO1 mRNA |
CTD |
PMID:16360708 |
|
NCBI chr16:24,980,680...24,997,927
Ensembl chr16:24,980,697...24,998,016
|
|
G |
Mtr |
5-methyltetrahydrofolate-homocysteine methyltransferase |
multiple interactions |
ISO |
[bisphenol A co-treated with Resveratrol co-treated with Corn Oil] results in increased expression of MTR mRNA |
CTD |
PMID:36432690 |
|
NCBI chr17:58,219,998...58,308,560
Ensembl chr17:58,220,071...58,304,822
|
|
G |
Mx2 |
MX dynamin like GTPase 2 |
affects expression |
EXP |
Corn Oil affects the expression of MX2 mRNA |
CTD |
PMID:16360708 |
|
NCBI chr11:36,905,698...36,936,308
Ensembl chr11:36,906,111...36,930,342
|
|
G |
Myd88 |
MYD88, innate immune signal transduction adaptor |
increases expression |
ISO |
Corn Oil results in increased expression of MYD88 mRNA |
CTD |
PMID:33263755 |
|
NCBI chr 8:119,074,439...119,078,508
Ensembl chr 8:119,074,437...119,079,415
|
|
G |
Nfe2l2 |
NFE2 like bZIP transcription factor 2 |
decreases activity |
ISO |
Corn Oil results in decreased activity of NFE2L2 protein |
CTD |
PMID:30203046 |
|
NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
|
|
G |
Nfkbia |
NFKB inhibitor alpha |
increases expression |
ISO |
Corn Oil results in increased expression of NFKBIA mRNA |
CTD |
PMID:33263755 |
|
NCBI chr 6:72,858,713...72,861,941
Ensembl chr 6:72,858,712...72,861,941
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G |
Nlrc4 |
NLR family, CARD domain containing 4 |
increases expression |
ISO |
Corn Oil results in increased expression of NLRC4 mRNA |
CTD |
PMID:33263755 |
|
NCBI chr 6:20,991,785...21,018,254
Ensembl chr 6:20,995,266...21,018,248
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G |
Nr1h4 |
nuclear receptor subfamily 1, group H, member 4 |
affects expression |
EXP |
Corn Oil affects the expression of NR1H4 mRNA |
CTD |
PMID:16360708 |
|
NCBI chr 7:23,846,122...23,942,085
Ensembl chr 7:23,846,122...23,942,047
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G |
Nr4a2 |
nuclear receptor subfamily 4, group A, member 2 |
increases expression |
EXP |
Corn Oil results in increased expression of NR4A2 mRNA |
CTD |
PMID:22760963 |
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NCBI chr 3:41,689,847...41,707,036
Ensembl chr 3:41,689,851...41,697,877
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G |
Nsmce3 |
NSE3 homolog, SMC5-SMC6 complex component |
affects expression |
EXP |
Corn Oil affects the expression of NSMCE3 mRNA |
CTD |
PMID:16360708 |
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NCBI chr 1:118,401,302...118,402,629
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G |
Oat |
ornithine aminotransferase |
affects expression |
EXP |
Corn Oil affects the expression of OAT mRNA |
CTD |
PMID:16360708 |
|
NCBI chr 1:187,347,862...187,367,644
Ensembl chr 1:187,347,865...187,367,682
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G |
Osgin1 |
oxidative stress induced growth inhibitor 1 |
affects expression |
EXP |
Corn Oil affects the expression of OSGIN1 mRNA |
CTD |
PMID:16360708 |
|
NCBI chr19:47,471,750...47,500,517
Ensembl chr19:47,492,171...47,500,516
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G |
P2rx5 |
purinergic receptor P2X 5 |
affects expression |
EXP |
Corn Oil affects the expression of P2RX5 mRNA |
CTD |
PMID:16360708 |
|
NCBI chr10:57,777,737...57,789,426
Ensembl chr10:57,777,819...57,789,423
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G |
Pax8 |
paired box 8 |
affects expression |
EXP |
Corn Oil affects the expression of PAX8 mRNA |
CTD |
PMID:16360708 |
|
NCBI chr 3:7,185,721...7,242,363
Ensembl chr 3:7,185,723...7,242,363
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G |
Pdgfa |
platelet derived growth factor subunit A |
affects expression |
EXP |
Corn Oil affects the expression of PDGFA mRNA |
CTD |
PMID:16360708 |
|
NCBI chr12:15,645,549...15,667,056
Ensembl chr12:15,645,541...15,666,497
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G |
Pdgfrb |
platelet derived growth factor receptor beta |
increases expression |
EXP |
Corn Oil results in increased expression of PDGFRB mRNA |
CTD |
PMID:22760963 |
|
NCBI chr18:54,499,962...54,538,840
Ensembl chr18:54,499,964...54,538,843
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G |
Pdlim1 |
PDZ and LIM domain 1 |
affects expression |
EXP |
Corn Oil affects the expression of PDLIM1 mRNA |
CTD |
PMID:16360708 |
|
NCBI chr 1:239,042,372...239,091,074
Ensembl chr 1:239,042,385...239,091,076
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G |
Pdlim2 |
PDZ and LIM domain 2 |
affects expression |
EXP |
Corn Oil affects the expression of PDLIM2 mRNA |
CTD |
PMID:16360708 |
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NCBI chr15:45,235,421...45,250,187
Ensembl chr15:45,237,477...45,249,242
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G |
Pgf |
placental growth factor |
increases expression |
EXP |
Corn Oil results in increased expression of PGF mRNA |
CTD |
PMID:22760963 |
|
NCBI chr 6:104,816,102...104,826,685
Ensembl chr 6:104,816,104...104,826,685
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G |
Pgrmc2 |
progesterone receptor membrane component 2 |
affects expression |
EXP |
Corn Oil affects the expression of PGRMC2 mRNA |
CTD |
PMID:16360708 |
|
NCBI chr 2:124,068,257...124,084,155
Ensembl chr 2:124,068,260...124,084,155
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G |
Pik3ca |
phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha |
increases expression |
ISO |
Corn Oil results in increased expression of PIK3CA mRNA |
CTD |
PMID:33263755 |
|
NCBI chr 2:115,175,275...115,249,034
Ensembl chr 2:115,174,984...115,249,032
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G |
Plin2 |
perilipin 2 |
affects expression |
EXP |
Corn Oil affects the expression of PLIN2 mRNA |
CTD |
PMID:16360708 |
|
NCBI chr 5:101,156,648...101,211,738
Ensembl chr 5:101,154,411...101,242,319
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G |
Prlr |
prolactin receptor |
affects expression |
EXP |
Corn Oil affects the expression of PRLR mRNA |
CTD |
PMID:16360708 |
|
NCBI chr 2:59,134,147...59,324,719
Ensembl chr 2:59,134,588...59,324,718
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G |
Ptgs2 |
prostaglandin-endoperoxide synthase 2 |
multiple interactions |
ISO |
[Estradiol co-treated with Progesterone co-treated with Corn Oil] results in increased expression of PTGS2 mRNA |
CTD |
PMID:32186404 |
|
NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
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G |
Ptprf |
protein tyrosine phosphatase, receptor type, F |
affects expression |
EXP |
Corn Oil affects the expression of PTPRF mRNA |
CTD |
PMID:16360708 |
|
NCBI chr 5:131,741,959...131,824,000
Ensembl chr 5:131,742,754...131,810,023
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G |
Pycard |
PYD and CARD domain containing |
increases expression |
ISO |
Corn Oil results in increased expression of PYCARD mRNA |
CTD |
PMID:33263755 |
|
NCBI chr 1:182,601,657...182,603,013
Ensembl chr 1:182,601,174...182,602,955
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G |
Rac1 |
Rac family small GTPase 1 |
increases expression |
ISO |
Corn Oil results in increased expression of RAC1 mRNA |
CTD |
PMID:33263755 |
|
NCBI chr12:11,037,028...11,057,251
Ensembl chr12:11,036,698...11,057,251
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G |
Ripk1 |
receptor interacting serine/threonine kinase 1 |
increases expression |
ISO |
Corn Oil results in increased expression of RIPK1 mRNA |
CTD |
PMID:33263755 |
|
NCBI chr17:30,839,639...30,871,824
Ensembl chr17:30,839,650...30,871,824
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G |
Ripk2 |
receptor-interacting serine-threonine kinase 2 |
increases expression |
ISO |
Corn Oil results in increased expression of RIPK2 mRNA |
CTD |
PMID:33263755 |
|
NCBI chr 5:29,630,806...29,662,804
Ensembl chr 5:29,631,570...29,662,657
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G |
RT1-A |
RT1 class I, locus A |
increases expression |
EXP |
Corn Oil results in increased expression of RT1-A mRNA |
CTD |
PMID:22760963 |
|
|
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G |
RT1-Bb |
RT1 class II, locus Bb |
increases expression |
EXP |
Corn Oil results in increased expression of RT1-BB mRNA |
CTD |
PMID:22760963 |
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NCBI chr20:4,596,558...4,602,201
Ensembl chr20:4,596,559...4,607,597
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G |
RT1-CE11 |
RT1 class I, locus CE11 |
decreases expression |
EXP |
Corn Oil results in decreased expression of RT1-CE11 mRNA |
CTD |
PMID:22760963 |
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NCBI chr20:3,355,393...3,358,520
Ensembl chr20:3,350,937...3,380,362
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G |
RT1-CE14 |
RT1 class I, locus CE14 |
increases expression |
EXP |
Corn Oil results in increased expression of RT1-CE14 mRNA |
CTD |
PMID:22760963 |
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NCBI chr20:3,296,654...3,300,795
Ensembl chr20:3,297,196...3,305,134
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G |
RT1-CE15 |
RT1 class I, locus CE15 |
decreases expression |
EXP |
Corn Oil results in decreased expression of RT1-CE15 mRNA |
CTD |
PMID:22760963 |
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NCBI chr20:3,275,575...3,279,074
Ensembl chr20:3,264,172...3,279,563 Ensembl chr20:3,264,172...3,279,563
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G |
RT1-CE16 |
RT1 class I, locus CE16 |
increases expression |
EXP |
Corn Oil results in increased expression of RT1-CE16 mRNA |
CTD |
PMID:22760963 |
|
NCBI chr20:3,257,109...3,260,747
Ensembl chr20:3,257,123...3,279,563
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G |
RT1-CE2 |
RT1 class I, locus CE2 |
increases expression |
EXP |
Corn Oil results in increased expression of RT1-CE2 mRNA |
CTD |
PMID:22760963 |
|
NCBI chr20:3,538,452...3,541,841
Ensembl chr20:3,537,809...3,541,790
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G |
RT1-CE3 |
RT1 class I, locus CE3 |
increases expression |
EXP |
Corn Oil results in increased expression of RT1-CE3 mRNA |
CTD |
PMID:22760963 |
|
NCBI chr20:3,516,647...3,520,938
Ensembl chr20:2,623,953...2,692,081
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G |
RT1-CE4 |
RT1 class I, locus CE4 |
increases expression |
EXP |
Corn Oil results in increased expression of RT1-CE4 mRNA |
CTD |
PMID:22760963 |
|
NCBI chr20:3,431,509...3,504,535
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G |
RT1-CE5 |
RT1 class I, locus CE5 |
increases expression |
EXP |
Corn Oil results in increased expression of RT1-CE5 mRNA |
CTD |
PMID:22760963 |
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NCBI chr20:3,403,418...3,479,476
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G |
RT1-N1 |
RT1 class Ib, locus N1 |
decreases expression |
EXP |
Corn Oil results in decreased expression of RT1-N1 mRNA |
CTD |
PMID:22760963 |
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G |
S100a8 |
S100 calcium binding protein A8 |
increases expression |
EXP |
Corn Oil results in increased expression of S100A8 mRNA |
CTD |
PMID:22760963 |
|
NCBI chr 2:176,166,517...176,167,645
Ensembl chr 2:176,167,124...176,167,643
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G |
S100a9 |
S100 calcium binding protein A9 |
increases expression |
EXP |
Corn Oil results in increased expression of S100A9 mRNA |
CTD |
PMID:22760963 |
|
NCBI chr 2:176,190,361...176,193,182
Ensembl chr 2:176,190,361...176,193,230
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G |
Scd |
stearoyl-CoA desaturase |
affects expression |
EXP |
Corn Oil affects the expression of SCD1 mRNA |
CTD |
PMID:16360708 |
|
NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562
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G |
Scn1b |
sodium voltage-gated channel beta subunit 1 |
affects expression |
EXP |
Corn Oil affects the expression of SCN1B mRNA |
CTD |
PMID:16360708 |
|
NCBI chr 1:86,353,917...86,363,820
Ensembl chr 1:86,353,917...86,363,739
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G |
Sds |
serine dehydratase |
affects expression |
EXP |
Corn Oil affects the expression of SDS mRNA |
CTD |
PMID:16360708 |
|
NCBI chr12:36,083,226...36,090,540
Ensembl chr12:36,083,229...36,088,203
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G |
Sfrp2 |
secreted frizzled-related protein 2 |
decreases expression |
EXP |
Corn Oil results in decreased expression of SFRP2 mRNA |
CTD |
PMID:22760963 |
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NCBI chr 2:169,089,517...169,097,064
Ensembl chr 2:169,089,517...169,097,063
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G |
Slc25a20 |
solute carrier family 25 member 20 |
multiple interactions |
ISO |
[bisphenol A co-treated with Resveratrol co-treated with Corn Oil] results in increased expression of SLC25A20 mRNA |
CTD |
PMID:36432690 |
|
NCBI chr 8:109,365,056...109,386,512
Ensembl chr 8:109,365,002...109,386,512
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G |
Slc25a25 |
solute carrier family 25 member 25 |
affects expression |
EXP |
Corn Oil affects the expression of SLC25A25 mRNA |
CTD |
PMID:16360708 |
|
NCBI chr 3:15,708,702...15,742,195
Ensembl chr 3:15,708,703...15,742,216
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G |
Sod1 |
superoxide dismutase 1 |
decreases activity multiple interactions |
ISO |
Corn Oil results in decreased activity of SOD1 protein [Corn Oil co-treated with Iron, Dietary] results in decreased activity of SOD1 protein; [Corn Oil co-treated with Iron] results in decreased activity of SOD1 protein; Iron promotes the reaction [Corn Oil results in decreased activity of SOD1 protein]; Iron, Dietary promotes the reaction [Corn Oil results in decreased activity of SOD1 protein] |
CTD |
PMID:17194920 |
|
NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
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G |
Sparc |
secreted protein acidic and cysteine rich |
increases expression |
EXP |
Corn Oil results in increased expression of SPARC mRNA |
CTD |
PMID:22760963 |
|
NCBI chr10:39,516,394...39,538,252
Ensembl chr10:39,516,406...39,538,396
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G |
Sqle |
squalene epoxidase |
affects expression |
EXP |
Corn Oil affects the expression of SQLE mRNA |
CTD |
PMID:16360708 |
|
NCBI chr 7:90,867,973...90,883,623
Ensembl chr 7:90,868,011...90,883,618
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G |
Srebf1 |
sterol regulatory element binding transcription factor 1 |
affects expression |
EXP |
Corn Oil affects the expression of SREBF1 mRNA |
CTD |
PMID:16360708 |
|
NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650
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G |
Sstr3 |
somatostatin receptor 3 |
decreases expression |
EXP |
Corn Oil results in decreased expression of SSTR3 mRNA |
CTD |
PMID:22760963 |
|
NCBI chr 7:110,092,563...110,109,043
Ensembl chr 7:110,092,575...110,099,769
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G |
Sugt1 |
SGT1 homolog, MIS12 kinetochore complex assembly cochaperone |
increases expression |
ISO |
Corn Oil results in increased expression of SUGT1 mRNA |
CTD |
PMID:33263755 |
|
NCBI chr15:54,991,419...55,032,244
Ensembl chr15:54,990,672...55,069,150
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G |
Syk |
spleen associated tyrosine kinase |
increases expression |
ISO |
Corn Oil results in increased expression of SYK mRNA |
CTD |
PMID:23409006 |
|
NCBI chr17:12,604,615...12,678,437
Ensembl chr17:12,604,619...12,661,410
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G |
Tac1 |
tachykinin, precursor 1 |
decreases expression |
EXP |
Corn Oil results in decreased expression of TAC1 mRNA |
CTD |
PMID:22760963 |
|
NCBI chr 4:35,679,183...35,687,180
Ensembl chr 4:35,679,704...35,687,178
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G |
Tat |
tyrosine aminotransferase |
affects expression |
EXP |
Corn Oil affects the expression of TAT mRNA |
CTD |
PMID:16360708 |
|
NCBI chr19:37,947,153...37,957,717
Ensembl chr19:37,947,112...37,958,031
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G |
Tbc1d14 |
TBC1 domain family, member 14 |
affects expression |
EXP |
Corn Oil affects the expression of TBC1D14 mRNA |
CTD |
PMID:16360708 |
|
NCBI chr14:74,172,652...74,272,182
Ensembl chr14:74,172,664...74,272,183
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G |
Tgfa |
transforming growth factor alpha |
decreases expression |
EXP |
Corn Oil results in decreased expression of TGFA mRNA |
CTD |
PMID:22760963 |
|
NCBI chr 4:118,618,043...118,700,897
Ensembl chr 4:118,618,269...118,700,894
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G |
Ticam1 |
TIR domain containing adaptor molecule 1 |
increases expression |
ISO |
Corn Oil results in increased expression of TICAM1 mRNA |
CTD |
PMID:33263755 |
|
NCBI chr 9:1,102,559...1,111,023
Ensembl chr 9:1,102,366...1,123,147
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G |
Tjp2 |
tight junction protein 2 |
increases expression |
ISO |
Corn Oil results in increased expression of TJP2 mRNA |
CTD |
PMID:33263755 |
|
NCBI chr 1:221,709,745...221,838,291
Ensembl chr 1:221,709,745...221,838,295
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G |
Tjp3 |
tight junction protein 3 |
increases expression |
ISO |
Corn Oil results in increased expression of TJP3 mRNA |
CTD |
PMID:33263755 |
|
NCBI chr 7:8,427,650...8,446,279
Ensembl chr 7:8,432,811...8,446,279
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G |
Tnfrsf1a |
TNF receptor superfamily member 1A |
increases expression |
ISO |
Corn Oil results in increased expression of TNFRSF1A mRNA |
CTD |
PMID:33263755 |
|
NCBI chr 4:158,150,815...158,163,592
Ensembl chr 4:158,150,820...158,163,591
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G |
Tollip |
toll interacting protein |
increases expression |
ISO |
Corn Oil results in increased expression of TOLLIP mRNA |
CTD |
PMID:33263755 |
|
NCBI chr 1:196,961,585...196,984,252
Ensembl chr 1:196,950,771...196,983,625
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G |
Tpcn2 |
two pore segment channel 2 |
affects expression |
EXP |
Corn Oil affects the expression of TPCN2 mRNA |
CTD |
PMID:16360708 |
|
NCBI chr 1:200,416,538...200,446,252
Ensembl chr 1:200,416,540...200,446,236
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G |
Tpt1 |
tumor protein, translationally-controlled 1 |
increases expression |
EXP |
Corn Oil results in increased expression of TPT1 mRNA |
CTD |
PMID:22760963 |
|
NCBI chr15:51,156,728...51,159,629
Ensembl chr15:51,146,154...51,159,625
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G |
Vegfb |
vascular endothelial growth factor B |
decreases expression |
EXP |
Corn Oil results in decreased expression of VEGFB mRNA |
CTD |
PMID:22760963 |
|
NCBI chr 1:204,172,297...204,178,046
Ensembl chr 1:204,172,225...204,177,944
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G |
Vnn1 |
vanin 1 |
affects expression |
EXP |
Corn Oil affects the expression of VNN1 mRNA |
CTD |
PMID:16360708 |
|
NCBI chr 1:21,537,084...21,547,395
Ensembl chr 1:21,537,094...21,547,395
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G |
Xiap |
X-linked inhibitor of apoptosis |
decreases expression |
ISO |
Corn Oil results in decreased expression of XIAP mRNA |
CTD |
PMID:33263755 |
|
NCBI chr X:120,890,537...120,938,413
Ensembl chr X:120,897,907...120,934,700
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G |
Xpnpep2 |
X-prolyl aminopeptidase 2 |
affects expression |
EXP |
Corn Oil affects the expression of XPNPEP2 mRNA |
CTD |
PMID:16360708 |
|
NCBI chr X:127,287,765...127,317,036
Ensembl chr X:127,287,979...127,317,223
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G |
Zdhhc23 |
zinc finger DHHC-type palmitoyltransferase 23 |
affects expression |
EXP |
Corn Oil affects the expression of ZDHHC23 mRNA |
CTD |
PMID:16360708 |
|
NCBI chr11:56,718,702...56,735,063
Ensembl chr11:56,718,826...56,734,194
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G |
Pgr |
progesterone receptor |
multiple interactions |
ISO |
erucyl amide binds to and results in decreased activity of PGR protein |
CTD |
PMID:27633901 |
|
NCBI chr 8:6,072,673...6,131,552
Ensembl chr 8:6,072,673...6,131,344
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G |
Nos2 |
nitric oxide synthase 2 |
increases expression multiple interactions |
EXP |
erucic acid results in increased expression of NOS2 protein erucic acid promotes the reaction [Doxorubicin results in increased expression of NOS2 protein] |
CTD |
PMID:30142312 |
|
NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
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G |
Nos3 |
nitric oxide synthase 3 |
multiple interactions increases expression |
EXP |
erucic acid promotes the reaction [Doxorubicin results in increased expression of NOS3 protein] erucic acid results in increased expression of NOS3 protein |
CTD |
PMID:30142312 |
|
NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166
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G |
Pon1 |
paraoxonase 1 |
multiple interactions |
ISO |
erucic acid inhibits the reaction [[Ascorbic Acid co-treated with Copper Sulfate] results in decreased activity of PON1 protein] |
CTD |
PMID:12871208 |
|
NCBI chr 4:33,294,737...33,325,759
Ensembl chr 4:33,294,722...33,321,360
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G |
Ahr |
aryl hydrocarbon receptor |
multiple interactions |
ISO |
methyl oleate binds to and results in increased activity of AHR protein |
CTD |
PMID:27633901 |
|
NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
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G |
Esr1 |
estrogen receptor 1 |
multiple interactions |
ISO |
methyl oleate binds to and results in increased activity of ESR1 protein |
CTD |
PMID:27633901 |
|
NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
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G |
Pparg |
peroxisome proliferator-activated receptor gamma |
multiple interactions |
ISO |
methyl oleate binds to and results in increased activity of PPARG protein |
CTD |
PMID:27633901 |
|
NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
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G |
Ache |
acetylcholinesterase |
multiple interactions decreases activity |
ISO EXP |
[Mevinphos co-treated with Dichlorvos] results in decreased activity of ACHE protein; asoxime chloride inhibits the reaction [Mevinphos results in decreased activity of ACHE protein]; HLo 7 inhibits the reaction [Mevinphos results in decreased activity of ACHE protein]; Obidoxime Chloride inhibits the reaction [Mevinphos results in decreased activity of ACHE protein]; pralidoxime inhibits the reaction [Mevinphos results in decreased activity of ACHE protein] |
CTD |
PMID:4859365 PMID:8783813 PMID:21251949 |
|
NCBI chr12:19,406,133...19,413,713
Ensembl chr12:19,407,360...19,413,651
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G |
Agtr1a |
angiotensin II receptor, type 1a |
increases expression multiple interactions |
EXP |
Mevinphos results in increased expression of AGTR1A mRNA; Mevinphos results in increased expression of AGTR1A protein [Mevinphos results in increased activity of AGTR1A protein] promotes the reaction [NOX1 protein results in increased abundance of Superoxides] |
CTD |
PMID:23824088 |
|
NCBI chr17:34,173,446...34,226,892
Ensembl chr17:34,174,429...34,226,946
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G |
Agtr2 |
angiotensin II receptor, type 2 |
multiple interactions increases expression |
EXP |
[Mevinphos results in increased activity of AGTR2 protein] which results in increased abundance of Peroxynitrous Acid Mevinphos results in increased expression of AGTR2 mRNA; Mevinphos results in increased expression of AGTR2 protein |
CTD |
PMID:23824088 |
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NCBI chr X:112,119,876...112,124,060
Ensembl chr X:112,120,228...112,124,057
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G |
Akt1 |
AKT serine/threonine kinase 1 |
increases phosphorylation multiple interactions |
EXP |
Mevinphos results in increased phosphorylation of AKT1 protein 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Mevinphos results in increased activity of and results in increased phosphorylation of AKT1 protein]; AKT1 protein modified form affects the reaction [Mevinphos results in increased activity of RELA protein]; Mevinphos results in increased activity of and results in increased phosphorylation of AKT1 protein; PI103 inhibits the reaction [Mevinphos results in increased activity of and results in increased phosphorylation of AKT1 protein]; Wortmannin inhibits the reaction [Mevinphos results in increased activity of and results in increased phosphorylation of AKT1 protein] |
CTD |
PMID:24462917 PMID:25449601 |
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NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
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G |
Arnt |
aryl hydrocarbon receptor nuclear translocator |
multiple interactions |
EXP |
ARNT protein affects the reaction [Mevinphos results in increased expression of NOS1 protein]; ARNT protein affects the reaction [Mevinphos results in increased expression of PRKG1 protein]; Mevinphos promotes the reaction [HIF1A protein binds to ARNT protein] |
CTD |
PMID:21390240 |
|
NCBI chr 2:182,997,731...183,056,584
Ensembl chr 2:182,997,736...183,056,580
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G |
Atf2 |
activating transcription factor 2 |
increases phosphorylation |
EXP |
Mevinphos results in increased phosphorylation of ATF2 protein |
CTD |
PMID:23157661 |
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NCBI chr 3:58,718,323...58,795,280
Ensembl chr 3:58,718,332...58,795,236
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G |
Bax |
BCL2 associated X, apoptosis regulator |
multiple interactions affects expression |
EXP |
HSPD1 protein affects the reaction [Mevinphos affects the expression of BAX protein]; Mevinphos promotes the reaction [HSPD1 protein binds to BAX protein] |
CTD |
PMID:17150954 |
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NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
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G |
Bcl2 |
BCL2, apoptosis regulator |
affects expression multiple interactions |
EXP |
Mevinphos affects the expression of BCL2 protein HSPD1 protein affects the reaction [Mevinphos affects the expression of BCL2 protein]; Mevinphos affects the reaction [HSPD1 protein binds to BCL2 protein] |
CTD |
PMID:17150954 |
|
NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
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G |
Casp3 |
caspase 3 |
increases activity multiple interactions |
EXP |
Mevinphos results in increased activity of CASP3 protein HSPD1 protein affects the reaction [Mevinphos results in increased activity of CASP3 protein] |
CTD |
PMID:17150954 |
|
NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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G |
Cep55 |
centrosomal protein 55 |
increases expression |
EXP |
Mevinphos results in increased expression of CEP55 mRNA; Mevinphos results in increased expression of CEP55 protein |
CTD |
PMID:25449601 |
|
NCBI chr 1:235,832,823...235,848,401
Ensembl chr 1:235,832,878...235,848,394
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G |
Chrm2 |
cholinergic receptor, muscarinic 2 |
increases activity |
EXP |
Mevinphos results in increased activity of CHRM2 protein |
CTD |
PMID:17395621 |
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NCBI chr 4:65,015,408...65,149,104
Ensembl chr 4:65,014,144...65,149,103
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G |
Chrm4 |
cholinergic receptor, muscarinic 4 |
increases activity |
EXP |
Mevinphos results in increased activity of CHRM4 protein |
CTD |
PMID:17395621 |
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NCBI chr 3:77,893,425...77,901,166
Ensembl chr 3:77,893,425...77,901,159
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G |
Hif1a |
hypoxia inducible factor 1 subunit alpha |
multiple interactions |
EXP |
HIF1A protein affects the reaction [Mevinphos results in increased expression of HMOX1 protein]; HIF1A protein affects the reaction [Mevinphos results in increased expression of NOS1 protein]; HIF1A protein affects the reaction [Mevinphos results in increased expression of PRKG1 protein]; Mevinphos promotes the reaction [HIF1A protein binds to ARNT protein]; Mevinphos promotes the reaction [HIF1A protein binds to SUMO1 protein]; Mevinphos results in increased expression of and affects the localization of HIF1A protein; Mevinphos results in increased expression of and results in increased activity of HIF1A protein; SUMO1 protein affects the reaction [Mevinphos results in increased expression of and results in increased activity of HIF1A protein]; UBE2I protein affects the reaction [Mevinphos results in increased expression of and results in increased activity of HIF1A protein] |
CTD |
PMID:19333137 PMID:21390240 |
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NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
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G |
Hmox1 |
heme oxygenase 1 |
increases expression multiple interactions |
EXP |
Mevinphos results in increased expression of HMOX1 protein HIF1A protein affects the reaction [Mevinphos results in increased expression of HMOX1 protein] |
CTD |
PMID:19333137 |
|
NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
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G |
Hspa9 |
heat shock protein family A (Hsp70) member 9 |
increases expression |
EXP |
Mevinphos results in increased expression of HSPA9 protein |
CTD |
PMID:17150954 |
|
NCBI chr18:26,536,131...26,554,294
Ensembl chr18:26,535,798...26,554,292
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G |
Hspd1 |
heat shock protein family D (Hsp60) member 1 |
multiple interactions increases expression |
EXP |
HSPD1 protein affects the reaction [Mevinphos affects the expression of BAX protein]; HSPD1 protein affects the reaction [Mevinphos affects the expression of BCL2 protein]; HSPD1 protein affects the reaction [Mevinphos results in increased activity of CASP3 protein]; HSPD1 protein affects the reaction [Mevinphos results in increased expression of NOS1 protein]; HSPD1 protein affects the reaction [Mevinphos results in increased expression of NOS2 protein]; HSPD1 protein affects the reaction [Mevinphos results in increased expression of PRKG1 protein]; Mevinphos affects the reaction [HSPD1 protein binds to BCL2 protein]; Mevinphos promotes the reaction [HSPD1 protein binds to BAX protein] Mevinphos results in increased expression of HSPD1 mRNA; Mevinphos results in increased expression of HSPD1 protein |
CTD |
PMID:17150954 |
|
NCBI chr 9:56,579,195...56,590,011
Ensembl chr 9:56,579,201...56,589,662
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G |
Il2 |
interleukin 2 |
decreases response to substance |
ISO |
Mevinphos results in decreased susceptibility to IL2 protein |
CTD |
PMID:8349949 |
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NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566
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G |
Jun |
Jun proto-oncogene, AP-1 transcription factor subunit |
increases phosphorylation |
EXP |
Mevinphos results in increased phosphorylation of JUN protein |
CTD |
PMID:23157661 |
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NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
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G |
Map2k4 |
mitogen activated protein kinase kinase 4 |
increases phosphorylation |
EXP |
Mevinphos results in increased phosphorylation of MAP2K4 protein |
CTD |
PMID:23157661 |
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NCBI chr10:50,343,227...50,447,956
Ensembl chr10:50,344,915...50,447,993
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G |
Map2k6 |
mitogen-activated protein kinase kinase 6 |
increases phosphorylation |
EXP |
Mevinphos results in increased phosphorylation of MAP2K6 protein |
CTD |
PMID:23157661 |
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NCBI chr10:95,373,304...95,490,406
Ensembl chr10:95,373,204...95,488,293
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G |
Nfkb1 |
nuclear factor kappa B subunit 1 |
multiple interactions |
EXP |
methoctramine inhibits the reaction [Mevinphos affects the localization of and affects the activity of NFKB1 protein]; Mevinphos affects the localization of and affects the activity of NFKB1 protein; Tropicamide inhibits the reaction [Mevinphos affects the localization of and affects the activity of NFKB1 protein] |
CTD |
PMID:17395621 |
|
NCBI chr 2:224,016,214...224,132,135
Ensembl chr 2:224,016,214...224,110,404
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G |
Nos1 |
nitric oxide synthase 1 |
multiple interactions increases activity increases expression |
EXP |
ARNT protein affects the reaction [Mevinphos results in increased expression of NOS1 protein]; HIF1A protein affects the reaction [Mevinphos results in increased expression of NOS1 protein]; HSPD1 protein affects the reaction [Mevinphos results in increased expression of NOS1 protein]; KT 5720 inhibits the reaction [Mevinphos results in increased expression of NOS1 protein]; methoctramine inhibits the reaction [Mevinphos results in increased expression of NOS1 protein]; N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Mevinphos results in increased expression of NOS1 protein]; Tropicamide inhibits the reaction [Mevinphos results in increased expression of NOS1 protein] Mevinphos results in increased activity of NOS1 protein Mevinphos results in increased expression of NOS1 mRNA; Mevinphos results in increased expression of NOS1 protein |
CTD |
PMID:15111025 PMID:15617736 PMID:17150954 PMID:17395621 PMID:17438462 PMID:21390240 PMID:24462917 PMID:28601397 More...
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NCBI chr12:38,615,111...38,795,492
Ensembl chr12:38,626,714...38,710,945
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G |
Nos2 |
nitric oxide synthase 2 |
multiple interactions increases activity increases expression |
EXP |
2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [Mevinphos results in increased expression of NOS2 protein]; HSPD1 protein affects the reaction [Mevinphos results in increased expression of NOS2 protein]; methoctramine inhibits the reaction [Mevinphos results in increased expression of NOS2 protein]; PTEN protein inhibits the reaction [Mevinphos results in increased expression of NOS2 mRNA]; PTEN protein inhibits the reaction [Mevinphos results in increased expression of NOS2 protein]; triciribine inhibits the reaction [Mevinphos results in increased expression of NOS2 protein]; Tropicamide inhibits the reaction [Mevinphos results in increased expression of NOS2 protein]; Wortmannin inhibits the reaction [Mevinphos results in increased expression of NOS2 protein] Mevinphos results in increased activity of NOS2 protein Mevinphos results in increased expression of NOS2; Mevinphos results in increased expression of NOS2 mRNA; Mevinphos results in increased expression of NOS2 protein |
CTD |
PMID:15111025 PMID:15617736 PMID:17150954 PMID:17395621 PMID:21390240 PMID:24462917 PMID:25449601 PMID:28601397 More...
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NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
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G |
Nox1 |
NADPH oxidase 1 |
multiple interactions |
EXP |
[Mevinphos results in increased activity of AGTR1A protein] promotes the reaction [NOX1 protein results in increased abundance of Superoxides] |
CTD |
PMID:23824088 |
|
NCBI chr X:97,279,058...97,332,291
Ensembl chr X:97,279,056...97,302,236
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G |
Pik3r1 |
phosphoinositide-3-kinase regulatory subunit 1 |
increases phosphorylation multiple interactions |
EXP |
Mevinphos results in increased phosphorylation of PIK3R1 protein PIK3R1 protein affects the reaction [Mevinphos results in increased activity of RELA protein] |
CTD |
PMID:24462917 |
|
NCBI chr 2:32,878,942...32,963,668
Ensembl chr 2:32,882,032...32,963,631
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G |
Prkg1 |
protein kinase cGMP-dependent 1 |
multiple interactions increases expression |
EXP |
1H-(1,2,4)oxadiazolo(4,3-a)quinoxalin-1-one inhibits the reaction [Mevinphos results in increased expression of PRKG1 protein]; 7-nitroindazole inhibits the reaction [Mevinphos results in increased expression of PRKG1 protein]; ARNT protein affects the reaction [Mevinphos results in increased expression of PRKG1 protein]; HIF1A protein affects the reaction [Mevinphos results in increased expression of PRKG1 protein]; HSPD1 protein affects the reaction [Mevinphos results in increased expression of PRKG1 protein] Mevinphos results in increased expression of PRKG1 mRNA; Mevinphos results in increased expression of PRKG1 protein |
CTD |
PMID:15617736 PMID:17150954 PMID:21390240 PMID:28601397 |
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NCBI chr 1:228,409,605...229,638,794
Ensembl chr 1:228,408,947...229,639,080
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G |
Pten |
phosphatase and tensin homolog |
multiple interactions |
EXP |
Mevinphos results in increased activity of and results in decreased oxidation of PTEN protein; PTEN protein inhibits the reaction [Mevinphos results in increased expression of NOS2 mRNA]; PTEN protein inhibits the reaction [Mevinphos results in increased expression of NOS2 protein] |
CTD |
PMID:28601397 |
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NCBI chr 1:230,630,443...230,697,070
Ensembl chr 1:230,630,338...230,696,838
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G |
Rela |
RELA proto-oncogene, NF-kB subunit |
multiple interactions increases activity |
EXP |
AKT1 protein modified form affects the reaction [Mevinphos results in increased activity of RELA protein]; methoctramine inhibits the reaction [Mevinphos affects the localization of and affects the activity of RELA protein]; Mevinphos affects the localization of and affects the activity of RELA protein; PIK3R1 protein affects the reaction [Mevinphos results in increased activity of RELA protein]; triciribine inhibits the reaction [Mevinphos results in increased activity of RELA protein]; Tropicamide inhibits the reaction [Mevinphos affects the localization of and affects the activity of RELA protein]; Wortmannin inhibits the reaction [Mevinphos results in increased activity of RELA protein] |
CTD |
PMID:17395621 PMID:24462917 |
|
NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
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G |
Sumo1 |
small ubiquitin-like modifier 1 |
multiple interactions |
EXP |
Mevinphos promotes the reaction [HIF1A protein binds to SUMO1 protein]; SUMO1 protein affects the reaction [Mevinphos results in increased expression of and results in increased activity of HIF1A protein] |
CTD |
PMID:21390240 |
|
NCBI chr 9:61,078,790...61,108,697
Ensembl chr 9:61,077,435...61,108,761
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G |
Tp53 |
tumor protein p53 |
affects activity |
ISO |
Mevinphos metabolite affects the activity of TP53 protein |
CTD |
PMID:35435491 |
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NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
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G |
Ube2i |
ubiquitin-conjugating enzyme E2I |
multiple interactions |
EXP |
Mevinphos results in increased expression of and results in increased activity of UBE2I protein; UBE2I protein affects the reaction [Mevinphos results in increased expression of and results in increased activity of HIF1A protein] |
CTD |
PMID:21390240 |
|
NCBI chr10:14,277,749...14,294,681
Ensembl chr10:69,701,618...69,702,443 Ensembl chr10:69,701,618...69,702,443
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G |
Uchl1 |
ubiquitin C-terminal hydrolase L1 |
multiple interactions increases expression |
EXP |
Cycloheximide inhibits the reaction [Mevinphos results in increased expression of UCHL1 protein]; Dactinomycin inhibits the reaction [Mevinphos results in increased expression of UCHL1 protein] |
CTD |
PMID:15545831 |
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NCBI chr14:41,485,031...41,495,590
Ensembl chr14:41,485,031...41,495,590
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G |
Nphs1 |
NPHS1 adhesion molecule, nephrin |
multiple interactions |
EXP |
Mycophenolate mofetil inhibits reaction [streptozotocin decreases expression of Nphs1 mRNA and protein in kidney] |
RGD |
PMID:17624267 |
RGD:38596322 |
NCBI chr 1:85,720,812...85,749,079
Ensembl chr 1:85,720,812...85,749,078
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G |
Abcf1 |
ATP binding cassette subfamily F member 1 |
increases expression |
ISO |
Mycophenolic Acid results in increased expression of ABCF1 mRNA |
CTD |
PMID:19818335 |
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NCBI chr20:2,802,519...2,815,433
Ensembl chr20:2,802,488...2,815,433
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G |
Adm |
adrenomedullin |
multiple interactions |
EXP |
Mycophenolic Acid inhibits the reaction [Mercuric Chloride results in increased expression of ADM protein] |
CTD |
PMID:15063164 |
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NCBI chr 1:164,745,484...164,747,655
Ensembl chr 1:164,745,466...164,747,654
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G |
Agt |
angiotensinogen |
decreases expression |
EXP |
Mycophenolic Acid results in decreased expression of AGT protein alternative form |
CTD |
PMID:15213268 |
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NCBI chr19:52,529,139...52,549,618
Ensembl chr19:52,529,185...52,540,977
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G |
Aif1 |
allograft inflammatory factor 1 |
decreases expression multiple interactions |
EXP |
Mycophenolic Acid results in decreased expression of AIF1 mRNA [Quercetin co-treated with Mycophenolic Acid] results in decreased expression of AIF1 mRNA |
CTD |
PMID:10688038 |
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NCBI chr20:3,646,784...3,652,670
Ensembl chr20:3,646,777...3,652,668
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G |
Aimp1 |
aminoacyl tRNA synthetase complex-interacting multifunctional protein 1 |
increases expression |
ISO |
Mycophenolic Acid results in increased expression of AIMP1 mRNA |
CTD |
PMID:19818335 |
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NCBI chr 2:221,151,907...221,175,458
Ensembl chr 2:221,151,904...221,175,728
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G |
Akt1 |
AKT serine/threonine kinase 1 |
increases expression |
ISO |
Mycophenolic Acid results in increased expression of AKT1 protein |
CTD |
PMID:21396949 |
|
NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
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G |
Alb |
albumin |
affects binding |
ISO |
Mycophenolic Acid binds to ALB protein |
CTD |
PMID:26892221 |
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NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
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G |
Ar |
androgen receptor |
multiple interactions |
ISO |
Mycophenolic Acid binds to and results in decreased activity of AR protein |
CTD |
PMID:25752796 |
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NCBI chr X:63,104,771...63,273,934
Ensembl chr X:63,104,771...63,273,925
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G |
Atf1 |
activating transcription factor 1 |
multiple interactions |
ISO |
Mycophenolic Acid inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of ATF1 protein] |
CTD |
PMID:20302854 |
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NCBI chr 7:131,361,962...131,404,677
Ensembl chr 7:131,362,450...131,404,670
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G |
Bak1 |
BCL2-antagonist/killer 1 |
increases expression |
ISO |
Mycophenolic Acid results in increased expression of BAK1 protein |
CTD |
PMID:16505121 |
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NCBI chr20:5,100,480...5,109,669
Ensembl chr20:5,100,480...5,109,264
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G |
Bax |
BCL2 associated X, apoptosis regulator |
multiple interactions |
ISO |
[Mycophenolic Acid co-treated with Hypoxanthine] results in increased expression of BAX protein |
CTD |
PMID:21396949 |
|
NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
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G |
Bcl2 |
BCL2, apoptosis regulator |
multiple interactions decreases expression |
ISO |
[Mycophenolic Acid co-treated with Hypoxanthine] results in decreased expression of BCL2 protein; Mycophenolic Acid inhibits the reaction [BCL2 protein results in decreased susceptibility to Dexamethasone]; schizandrin A inhibits the reaction [Mycophenolic Acid results in decreased expression of BCL2 protein] |
CTD |
PMID:16505121 PMID:21396949 PMID:35321622 |
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NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
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G |
Casp1 |
caspase 1 |
increases expression |
ISO |
Mycophenolic Acid results in increased expression of CASP1 mRNA |
CTD |
PMID:19818335 |
|
NCBI chr 8:2,587,812...2,597,403
Ensembl chr 8:2,587,831...2,597,383
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G |
Casp3 |
caspase 3 |
increases activity increases cleavage multiple interactions |
ISO |
Mycophenolic Acid results in increased activity of CASP3 protein Mycophenolic Acid results in increased cleavage of CASP3 protein [Mycophenolic Acid co-treated with Hypoxanthine] results in increased activity of CASP3 protein; schizandrin A inhibits the reaction [Mycophenolic Acid results in increased cleavage of CASP3 protein] |
CTD |
PMID:16059982 PMID:16505121 PMID:21396949 PMID:35321622 |
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NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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G |
Ccl19 |
C-C motif chemokine ligand 19 |
increases expression |
ISO |
Mycophenolic Acid results in increased expression of CCL19 mRNA |
CTD |
PMID:19818335 |
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NCBI chr 5:56,963,364...56,965,308
Ensembl chr 5:56,963,364...56,965,308
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G |
Ccl2 |
C-C motif chemokine ligand 2 |
multiple interactions |
EXP |
Mycophenolic Acid inhibits the reaction [Streptozocin results in increased expression of CCL2 mRNA]; Mycophenolic Acid inhibits the reaction [Streptozocin results in increased expression of CCL2 protein] |
CTD |
PMID:17624267 |
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NCBI chr10:67,005,424...67,007,222
Ensembl chr10:67,005,424...67,007,226
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G |
Ccl20 |
C-C motif chemokine ligand 20 |
decreases expression increases expression |
ISO |
Mycophenolic Acid results in decreased expression of CCL20 mRNA Mycophenolic Acid results in increased expression of CCL20 mRNA |
CTD |
PMID:19818335 |
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NCBI chr 9:84,389,031...84,391,629
Ensembl chr 9:84,388,904...84,391,629
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G |
Ccl22 |
C-C motif chemokine ligand 22 |
increases expression |
ISO |
Mycophenolic Acid results in increased expression of CCL22 mRNA |
CTD |
PMID:19818335 |
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NCBI chr19:10,257,602...10,264,373
Ensembl chr19:10,257,601...10,264,400
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G |
Ccl25 |
C-C motif chemokine ligand 25 |
increases expression |
ISO |
Mycophenolic Acid results in increased expression of CCL25 mRNA |
CTD |
PMID:19818335 |
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NCBI chr12:2,707,398...2,716,571
Ensembl chr12:2,707,398...2,716,554
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G |
Ccl4 |
C-C motif chemokine ligand 4 |
decreases expression |
ISO |
Mycophenolic Acid results in decreased expression of CCL4 mRNA |
CTD |
PMID:19818335 |
|
NCBI chr10:68,466,394...68,468,229
Ensembl chr10:68,452,052...68,468,231
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G |
Ccl5 |
C-C motif chemokine ligand 5 |
multiple interactions decreases expression |
EXP |
[Quercetin co-treated with Mycophenolic Acid] results in decreased expression of CCL5 mRNA Mycophenolic Acid results in decreased expression of CCL5 mRNA |
CTD |
PMID:10688038 |
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NCBI chr10:68,322,826...68,327,380
Ensembl chr10:68,322,829...68,327,377
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G |
Ccl7 |
C-C motif chemokine ligand 7 |
decreases expression |
ISO |
Mycophenolic Acid results in decreased expression of CCL7 mRNA |
CTD |
PMID:19818335 |
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NCBI chr10:67,016,446...67,018,296
Ensembl chr10:67,016,446...67,018,303
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G |
Ccl9 |
C-C motif chemokine ligand 9 |
decreases expression increases expression |
ISO |
Mycophenolic Acid results in decreased expression of CCL6 mRNA Mycophenolic Acid results in increased expression of CCL6 mRNA |
CTD |
PMID:19818335 |
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NCBI chr10:68,366,486...68,371,408
Ensembl chr10:68,366,487...68,371,369
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G |
Ccr10 |
C-C motif chemokine receptor 10 |
increases expression |
ISO |
Mycophenolic Acid results in increased expression of CCR10 mRNA |
CTD |
PMID:19818335 |
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NCBI chr10:86,108,551...86,110,988
Ensembl chr10:86,108,551...86,110,988
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G |
Ccr2 |
C-C motif chemokine receptor 2 |
increases expression |
ISO |
Mycophenolic Acid results in increased expression of CCR2 mRNA |
CTD |
PMID:19818335 |
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NCBI chr 8:123,734,465...123,742,483
Ensembl chr 8:123,734,430...123,742,100
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G |
Ccr3 |
C-C motif chemokine receptor 3 |
increases expression |
ISO |
Mycophenolic Acid results in increased expression of CCR3 mRNA |
CTD |
PMID:19818335 |
|
NCBI chr 8:123,586,100...123,634,178
Ensembl chr 8:123,616,236...123,634,990
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G |
Ccr6 |
C-C motif chemokine receptor 6 |
increases expression |
ISO |
Mycophenolic Acid results in increased expression of CCR6 mRNA |
CTD |
PMID:19818335 |
|
NCBI chr 1:52,474,477...52,508,301
Ensembl chr 1:52,474,168...52,498,603
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G |
Ccr9 |
C-C motif chemokine receptor 9 |
increases expression |
ISO |
Mycophenolic Acid results in increased expression of CCR9 mRNA |
CTD |
PMID:19818335 |
|
NCBI chr 8:123,396,157...123,410,199
Ensembl chr 8:123,395,813...123,413,969
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G |
Cd40lg |
CD40 ligand |
increases expression |
ISO |
Mycophenolic Acid results in increased expression of CD40LG mRNA |
CTD |
PMID:19818335 |
|
NCBI chr X:135,127,052...135,138,768
Ensembl chr X:135,126,969...135,138,306
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G |
Cdkn1b |
cyclin-dependent kinase inhibitor 1B |
multiple interactions |
ISO |
Mycophenolic Acid inhibits the reaction [IL2 protein results in decreased expression of CDKN1B protein] |
CTD |
PMID:12193749 |
|
NCBI chr 4:167,760,067...167,765,177
Ensembl chr 4:167,760,181...167,764,982
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G |
Creb1 |
cAMP responsive element binding protein 1 |
multiple interactions |
ISO |
Mycophenolic Acid inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of CREB1 protein] |
CTD |
PMID:20302854 |
|
NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816
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|
G |
Cx3cl1 |
C-X3-C motif chemokine ligand 1 |
increases expression |
ISO |
Mycophenolic Acid results in increased expression of CX3CL1 mRNA |
CTD |
PMID:19818335 |
|
NCBI chr19:10,227,337...10,237,826
Ensembl chr19:10,227,340...10,236,833
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G |
Cxcl12 |
C-X-C motif chemokine ligand 12 |
increases expression |
ISO |
Mycophenolic Acid results in increased expression of CXCL12 mRNA |
CTD |
PMID:19818335 |
|
NCBI chr 4:150,388,326...150,401,173
Ensembl chr 4:150,388,325...150,401,168
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G |
Cxcl2 |
C-X-C motif chemokine ligand 2 |
increases expression |
ISO |
Mycophenolic Acid results in increased expression of CXCL2 protein |
CTD |
PMID:19818335 |
|
NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075
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|
G |
Cxcl3 |
C-X-C motif chemokine ligand 3 |
decreases expression increases expression |
ISO |
Mycophenolic Acid results in decreased expression of CXCL1 mRNA Mycophenolic Acid results in increased expression of CXCL1 mRNA |
CTD |
PMID:19818335 |
|
NCBI chr14:17,287,727...17,289,451
Ensembl chr14:17,270,146...17,289,511
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|
G |
Cxcl6 |
C-X-C motif chemokine ligand 6 |
increases expression decreases expression |
ISO |
Mycophenolic Acid results in increased expression of CXCL5 mRNA Mycophenolic Acid results in decreased expression of CXCL5 mRNA |
CTD |
PMID:19818335 |
|
NCBI chr14:17,310,790...17,312,250
Ensembl chr14:17,310,426...17,313,093
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G |
Cxcr2 |
C-X-C motif chemokine receptor 2 |
increases expression |
ISO |
Mycophenolic Acid results in increased expression of CXCR2 mRNA |
CTD |
PMID:19818335 |
|
NCBI chr 9:75,729,493...75,735,868
Ensembl chr 9:75,729,115...75,739,425
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|
G |
Cxcr3 |
C-X-C motif chemokine receptor 3 |
increases expression |
ISO |
Mycophenolic Acid results in increased expression of CXCR3 mRNA |
CTD |
PMID:19818335 |
|
NCBI chr X:66,844,318...66,846,969
Ensembl chr X:66,844,318...66,846,969
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|
G |
Cxcr5 |
C-X-C motif chemokine receptor 5 |
increases expression |
ISO |
Mycophenolic Acid results in increased expression of CXCR5 mRNA |
CTD |
PMID:19818335 |
|
NCBI chr 8:44,842,098...44,858,425
Ensembl chr 8:44,843,413...44,857,893
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|
G |
Cycs |
cytochrome c, somatic |
increases secretion |
ISO |
Mycophenolic Acid results in increased secretion of CYCS protein |
CTD |
PMID:16505121 |
|
NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054 Ensembl chr18:79,651,378...79,654,054
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G |
Cyp1a1 |
cytochrome P450, family 1, subfamily a, polypeptide 1 |
increases expression multiple interactions |
ISO |
Mycophenolic Acid results in increased expression of CYP1A1 mRNA Mycophenolic Acid affects the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA]; Mycophenolic Acid promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A1 mRNA]; Mycophenolic Acid promotes the reaction [Esomeprazole results in increased expression of CYP1A1 mRNA]; Mycophenolic Acid promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A1 mRNA] |
CTD |
PMID:25929522 |
|
NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
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|
G |
Cyp1a2 |
cytochrome P450, family 1, subfamily a, polypeptide 2 |
multiple interactions |
ISO |
Mycophenolic Acid promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of CYP1A2 mRNA] |
CTD |
PMID:25929522 |
|
NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
|
|
G |
Cyp2c79 |
cytochrome P450, family 2, subfamily c, polypeptide 79 |
increases methylation |
ISO |
CYP2C8 protein results in increased methylation of Mycophenolic Acid |
CTD |
PMID:15570183 |
|
|
|
G |
Cyp3a2 |
cytochrome P450, family 3, subfamily a, polypeptide 2 |
multiple interactions increases methylation |
ISO |
[Mycophenolic Acid results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA CYP3A4 protein results in increased methylation of Mycophenolic Acid |
CTD |
PMID:15570183 PMID:25455453 |
|
NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008
|
|
G |
Cyp3a9 |
cytochrome P450, family 3, subfamily a, polypeptide 9 |
increases methylation |
ISO |
CYP3A5 protein results in increased methylation of Mycophenolic Acid |
CTD |
PMID:15570183 |
|
NCBI chr12:16,806,222...16,846,428
Ensembl chr12:16,806,207...16,846,422
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G |
Des |
desmin |
multiple interactions |
EXP |
Mycophenolic Acid inhibits the reaction [Streptozocin results in increased expression of DES protein] |
CTD |
PMID:17624267 |
|
NCBI chr 9:76,850,979...76,858,695
Ensembl chr 9:76,850,982...76,858,699
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|
G |
Esr1 |
estrogen receptor 1 |
multiple interactions |
ISO |
Mycophenolic Acid binds to and results in decreased activity of ESR1 protein |
CTD |
PMID:25752796 |
|
NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
|
|
G |
Esr2 |
estrogen receptor 2 |
multiple interactions |
ISO |
Mycophenolic Acid binds to and results in decreased activity of ESR2 protein |
CTD |
PMID:25752796 |
|
NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919
|
|
G |
Fos |
Fos proto-oncogene, AP-1 transcription factor subunit |
increases expression |
ISO |
Mycophenolic Acid results in increased expression of FOS mRNA |
CTD |
PMID:12730611 |
|
NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
|
|
G |
Gsk3b |
glycogen synthase kinase 3 beta |
multiple interactions |
ISO |
Mycophenolic Acid inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of GSK3B protein] |
CTD |
PMID:20302854 |
|
NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
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|
G |
Hspa5 |
heat shock protein family A (Hsp70) member 5 |
decreases expression |
ISO |
Mycophenolic Acid results in decreased expression of HSPA5 mRNA |
CTD |
PMID:24356939 |
|
NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
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|
G |
Ifng |
interferon gamma |
decreases expression multiple interactions |
EXP ISO |
Mycophenolic Acid results in decreased expression of IFNG mRNA [Mycophenolic Acid co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IFNG mRNA |
CTD |
PMID:11562063 PMID:29594315 |
|
NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
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|
G |
Il10 |
interleukin 10 |
decreases expression |
EXP |
Mycophenolic Acid results in decreased expression of IL10 mRNA |
CTD |
PMID:11562063 |
|
NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
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G |
Il10ra |
interleukin 10 receptor subunit alpha |
increases expression |
ISO |
Mycophenolic Acid results in increased expression of IL10RA mRNA |
CTD |
PMID:19818335 |
|
NCBI chr 8:45,563,009...45,578,041
Ensembl chr 8:45,563,137...45,578,061
|
|
G |
Il10rb |
interleukin 10 receptor subunit beta |
increases expression |
ISO |
Mycophenolic Acid results in increased expression of IL10RB mRNA |
CTD |
PMID:19818335 |
|
NCBI chr11:30,646,494...30,668,081
Ensembl chr11:30,652,096...30,668,074
|
|
G |
Il11 |
interleukin 11 |
increases expression |
ISO |
Mycophenolic Acid results in increased expression of IL11 mRNA |
CTD |
PMID:19818335 |
|
NCBI chr 1:69,069,829...69,076,129
Ensembl chr 1:69,068,137...69,076,129
|
|
G |
Il12rb2 |
interleukin 12 receptor subunit beta 2 |
decreases expression |
EXP |
Mycophenolic Acid results in decreased expression of IL12RB2 mRNA |
CTD |
PMID:11562063 |
|
NCBI chr 4:96,426,396...96,515,251
Ensembl chr 4:96,426,842...96,515,289
|
|
G |
Il13 |
interleukin 13 |
increases expression |
ISO |
Mycophenolic Acid results in increased expression of IL13 mRNA |
CTD |
PMID:19818335 |
|
NCBI chr10:37,790,130...37,792,687
Ensembl chr10:37,790,130...37,792,737
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|
G |
Il15 |
interleukin 15 |
increases expression |
ISO |
Mycophenolic Acid results in increased expression of IL15 mRNA |
CTD |
PMID:19818335 |
|
NCBI chr19:25,640,025...25,706,818
Ensembl chr19:25,640,251...25,706,820
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|
G |
Il16 |
interleukin 16 |
increases expression |
ISO |
Mycophenolic Acid results in increased expression of IL16 mRNA |
CTD |
PMID:19818335 |
|
NCBI chr 1:137,617,702...137,718,022
Ensembl chr 1:137,617,944...137,718,130
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|
G |
Il18 |
interleukin 18 |
decreases expression |
ISO |
Mycophenolic Acid results in decreased expression of IL18 mRNA |
CTD |
PMID:19818335 |
|
NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887
|
|
G |
Il1r1 |
interleukin 1 receptor type 1 |
increases expression |
ISO |
Mycophenolic Acid results in increased expression of IL1R1 mRNA |
CTD |
PMID:19818335 |
|
NCBI chr 9:42,504,917...42,580,958
Ensembl chr 9:42,504,735...42,579,937
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|
G |
Il1r2 |
interleukin 1 receptor type 2 |
increases expression |
ISO |
Mycophenolic Acid results in increased expression of IL1R2 mRNA |
CTD |
PMID:19818335 |
|
NCBI chr 9:42,384,280...42,424,726
Ensembl chr 9:42,384,433...42,424,725
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|
G |
Il2 |
interleukin 2 |
multiple interactions decreases expression |
ISO EXP |
[Mycophenolic Acid co-treated with Ionomycin co-treated with Tetradecanoylphorbol Acetate] results in increased expression of IL2 mRNA; Mycophenolic Acid inhibits the reaction [IL2 protein results in decreased expression of CDKN1B protein] Mycophenolic Acid results in decreased expression of IL2 mRNA |
CTD |
PMID:11562063 PMID:12193749 PMID:29594315 |
|
NCBI chr 2:120,004,862...120,009,566
Ensembl chr 2:120,004,862...120,009,566
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G |
Il2rb |
interleukin 2 receptor subunit beta |
increases expression |
ISO |
Mycophenolic Acid results in increased expression of IL2RB mRNA |
CTD |
PMID:19818335 |
|
NCBI chr 7:110,033,341...110,048,054
Ensembl chr 7:110,033,341...110,048,054
|
|
G |
Il2rg |
interleukin 2 receptor subunit gamma |
increases expression |
ISO |
Mycophenolic Acid results in increased expression of IL2RG mRNA |
CTD |
PMID:19818335 |
|
NCBI chr X:66,395,330...66,399,026
Ensembl chr X:66,392,542...66,399,823
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|
G |
Il3 |
interleukin 3 |
increases expression |
ISO |
Mycophenolic Acid results in increased expression of IL3 mRNA |
CTD |
PMID:19818335 |
|
NCBI chr10:38,405,716...38,408,066
Ensembl chr10:38,405,716...38,408,066
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|
G |
Il4 |
interleukin 4 |
decreases expression |
EXP |
Mycophenolic Acid results in decreased expression of IL4 mRNA |
CTD |
PMID:11562063 |
|
NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
|
|
G |
Il5ra |
interleukin 5 receptor subunit alpha |
increases expression |
ISO |
Mycophenolic Acid results in increased expression of IL5RA mRNA |
CTD |
PMID:19818335 |
|
NCBI chr 4:139,630,652...139,664,593
Ensembl chr 4:139,632,066...139,668,544
|
|
G |
Il6 |
interleukin 6 |
increases expression |
ISO |
Mycophenolic Acid results in increased expression of IL6 protein |
CTD |
PMID:11981085 |
|
NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
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|
G |
Il6r |
interleukin 6 receptor |
increases expression |
ISO |
Mycophenolic Acid results in increased expression of IL6RA mRNA |
CTD |
PMID:19818335 |
|
NCBI chr 2:175,289,157...175,347,719
Ensembl chr 2:175,298,686...175,347,536
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|
G |
Il6st |
interleukin 6 cytokine family signal transducer |
increases expression |
ISO |
Mycophenolic Acid results in increased expression of IL6ST mRNA |
CTD |
PMID:19818335 |
|
NCBI chr 2:44,065,979...44,106,255
Ensembl chr 2:44,066,130...44,109,936
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|
G |
Impdh2 |
inosine monophosphate dehydrogenase 2 |
increases expression |
EXP |
Mycophenolic Acid results in increased expression of IMPDH2 mRNA |
CTD |
PMID:11145582 |
|
NCBI chr 8:109,256,705...109,261,365
Ensembl chr 8:109,256,728...109,261,359
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|
G |
Itgam |
integrin subunit alpha M |
increases expression |
ISO |
Mycophenolic Acid results in increased expression of ITGAM mRNA |
CTD |
PMID:19818335 |
|
NCBI chr 1:182,659,047...182,709,501
Ensembl chr 1:182,659,000...182,709,503
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|
G |
Klrk1 |
killer cell lectin like receptor K1 |
decreases expression |
ISO |
Mycophenolic Acid results in decreased expression of KLRK1 |
CTD |
PMID:20736080 |
|
NCBI chr 4:163,079,887...163,092,434
Ensembl chr 4:163,081,927...163,092,459
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|
G |
Krcc1 |
lysine-rich coiled-coil 1 |
decreases expression |
ISO |
Mycophenolic Acid results in decreased expression of KRCC1 mRNA |
CTD |
PMID:24356939 |
|
NCBI chr 4:103,261,642...103,274,672
Ensembl chr 4:103,261,536...103,277,156
|
|
G |
Lrrc37a |
leucine rich repeat containing 37A |
decreases expression |
ISO |
Mycophenolic Acid results in decreased expression of LRRC37A3 mRNA |
CTD |
PMID:24356939 |
|
NCBI chr10:88,395,837...88,433,519
Ensembl chr10:88,396,663...88,433,323
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|
G |
Lta |
lymphotoxin alpha |
increases expression |
ISO |
Mycophenolic Acid results in increased expression of LTA mRNA |
CTD |
PMID:19818335 |
|
NCBI chr20:3,618,853...3,621,324
Ensembl chr20:3,618,853...3,620,859
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|
G |
Ltb |
lymphotoxin beta |
increases expression |
ISO |
Mycophenolic Acid results in increased expression of LTB mRNA |
CTD |
PMID:19818335 |
|
NCBI chr20:3,627,536...3,629,381
Ensembl chr20:3,627,537...3,629,381
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|
G |
Lyn |
LYN proto-oncogene, Src family tyrosine kinase |
multiple interactions |
ISO |
[Mycophenolic Acid co-treated with Imatinib Mesylate] results in decreased phosphorylation of LYN protein |
CTD |
PMID:15604220 |
|
NCBI chr 5:16,639,512...16,755,501
Ensembl chr 5:16,639,466...16,756,868
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|
G |
Mapk1 |
mitogen activated protein kinase 1 |
multiple interactions increases phosphorylation decreases expression |
ISO |
Mycophenolic Acid inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK1 protein]; schizandrin A inhibits the reaction [Mycophenolic Acid results in increased phosphorylation of MAPK1 protein] Mycophenolic Acid results in decreased expression of MAPK1 protein modified form |
CTD |
PMID:20302854 PMID:35321622 |
|
NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
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|
G |
Mapk3 |
mitogen activated protein kinase 3 |
multiple interactions increases phosphorylation decreases expression |
ISO |
Mycophenolic Acid inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK3 protein]; schizandrin A inhibits the reaction [Mycophenolic Acid results in increased phosphorylation of MAPK3 protein] Mycophenolic Acid results in decreased expression of MAPK3 protein modified form |
CTD |
PMID:20302854 PMID:35321622 |
|
NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
|
|
G |
Mapk8 |
mitogen-activated protein kinase 8 |
multiple interactions increases phosphorylation decreases expression |
ISO EXP |
Mycophenolic Acid inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK8 protein]; schizandrin A inhibits the reaction [Mycophenolic Acid results in increased phosphorylation of MAPK8 protein] Mycophenolic Acid results in decreased expression of MAPK8 protein modified form |
CTD |
PMID:20302854 PMID:35321622 |
|
NCBI chr16:8,638,897...8,721,960
Ensembl chr16:8,638,924...8,721,981
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|
G |
Mapk9 |
mitogen-activated protein kinase 9 |
multiple interactions decreases expression |
ISO EXP |
Mycophenolic Acid inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK9 protein] Mycophenolic Acid results in decreased expression of MAPK9 protein modified form |
CTD |
PMID:20302854 |
|
NCBI chr10:34,169,661...34,211,138
Ensembl chr10:34,169,675...34,210,178
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|
G |
Mapt |
microtubule-associated protein tau |
decreases expression |
ISO |
Mycophenolic Acid results in decreased expression of MAPT protein |
CTD |
PMID:16930453 |
|
NCBI chr10:89,138,644...89,236,137
Ensembl chr10:89,138,627...89,236,129
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|
G |
Mif |
macrophage migration inhibitory factor |
increases expression |
ISO |
Mycophenolic Acid results in increased expression of MIF mRNA |
CTD |
PMID:19818335 |
|
NCBI chr20:12,790,919...12,791,784
Ensembl chr20:12,790,902...12,799,504
|
|
G |
Nanos1 |
nanos C2HC-type zinc finger 1 |
increases expression |
ISO |
Mycophenolic Acid results in increased expression of NANOS1 mRNA |
CTD |
PMID:24356939 |
|
NCBI chr 1:259,897,663...259,901,561
Ensembl chr 1:259,897,939...259,898,730
|
|
G |
Ncr1 |
natural cytotoxicity triggering receptor 1 |
decreases expression |
ISO |
Mycophenolic Acid results in decreased expression of NCR1 |
CTD |
PMID:20736080 |
|
NCBI chr 1:69,614,744...69,622,594
Ensembl chr 1:69,616,601...69,660,558
|
|
G |
Ncr2 |
natural cytotoxicity triggering receptor 2 |
decreases expression |
ISO |
Mycophenolic Acid results in decreased expression of NCR2 |
CTD |
PMID:20736080 |
|
NCBI chr 9:12,777,195...12,828,437
|
|
G |
Ncr3 |
natural cytotoxicity triggering receptor 3 |
decreases expression |
ISO |
Mycophenolic Acid results in decreased expression of NCR3 |
CTD |
PMID:20736080 |
|
NCBI chr20:3,637,242...3,643,748
Ensembl chr20:3,638,240...3,643,799
|
|
G |
Nr1i2 |
nuclear receptor subfamily 1, group I, member 2 |
increases activity multiple interactions |
ISO |
Mycophenolic Acid results in increased activity of NR1I2 protein [Mycophenolic Acid results in increased activity of NR1I2 protein] which results in increased expression of CYP3A4 mRNA |
CTD |
PMID:25455453 |
|
NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
|
|
G |
Ocln |
occludin |
multiple interactions decreases expression |
ISO |
schizandrin A inhibits the reaction [Mycophenolic Acid results in decreased expression of OCLN protein] |
CTD |
PMID:35321622 |
|
NCBI chr 2:31,657,217...31,707,466
Ensembl chr 2:31,657,220...31,764,150
|
|
G |
Pdcd4 |
programmed cell death 4 |
increases expression |
ISO |
Mycophenolic Acid results in increased expression of PDCD4 mRNA |
CTD |
PMID:24356939 |
|
NCBI chr 1:252,921,342...252,944,278
Ensembl chr 1:252,921,392...252,944,275
|
|
G |
Pgr |
progesterone receptor |
multiple interactions |
ISO |
Mycophenolic Acid binds to and results in decreased activity of PGR protein |
CTD |
PMID:25752796 |
|
NCBI chr 8:6,072,673...6,131,552
Ensembl chr 8:6,072,673...6,131,344
|
|
G |
Prkca |
protein kinase C, alpha |
increases expression |
ISO |
Mycophenolic Acid results in increased expression of PRKCA protein |
CTD |
PMID:21396949 |
|
NCBI chr10:92,889,390...93,288,013
Ensembl chr10:92,894,012...93,288,012
|
|
G |
Rac1 |
Rac family small GTPase 1 |
multiple interactions |
EXP |
Mycophenolic Acid inhibits the reaction [RAC1 protein results in increased abundance of Reactive Oxygen Species] |
CTD |
PMID:17950325 |
|
NCBI chr12:11,037,028...11,057,251
Ensembl chr12:11,036,698...11,057,251
|
|
G |
Rela |
RELA proto-oncogene, NF-kB subunit |
decreases expression multiple interactions |
EXP ISO |
Mycophenolic Acid results in decreased expression of RELA protein modified form Mycophenolic Acid inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of RELA protein] |
CTD |
PMID:20302854 |
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NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
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G |
Rgs2 |
regulator of G-protein signaling 2 |
increases expression |
ISO |
Mycophenolic Acid results in increased expression of RGS2 mRNA |
CTD |
PMID:24356939 |
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NCBI chr13:55,799,749...55,802,354
Ensembl chr13:55,798,829...55,802,385
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G |
Rps6 |
ribosomal protein S6 |
multiple interactions |
ISO |
[Mycophenolic Acid co-treated with Imatinib Mesylate] results in decreased phosphorylation of RPS6 protein |
CTD |
PMID:15604220 |
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NCBI chr 5:101,371,716...101,374,576
Ensembl chr 5:101,371,136...101,374,602 Ensembl chr 5:101,371,136...101,374,602
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G |
Slc22a2 |
solute carrier family 22 member 2 |
multiple interactions |
ISO |
Mycophenolic Acid inhibits the reaction [SLC22A2 protein results in increased uptake of 4-(4-dimethylaminostyryl)-1-methylpyridinium] |
CTD |
PMID:21599003 |
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NCBI chr 1:48,121,061...48,163,268
Ensembl chr 1:48,121,061...48,163,268
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G |
Slc7a11 |
solute carrier family 7 member 11 |
decreases expression |
ISO |
Mycophenolic Acid results in decreased expression of SLC7A11 mRNA |
CTD |
PMID:24356939 |
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NCBI chr 2:134,382,002...134,517,622
Ensembl chr 2:133,963,107...134,517,536
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G |
Spmip11 |
sperm microtubule inner protein 11 |
multiple interactions |
EXP |
Mycophenolic Acid inhibits the reaction [Streptozocin results in decreased expression of NPHS1 mRNA]; Mycophenolic Acid inhibits the reaction [Streptozocin results in decreased expression of NPHS1 protein] |
CTD |
PMID:17624267 |
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NCBI chr 7:129,720,950...129,742,485
Ensembl chr 7:129,720,950...129,742,485
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G |
Spp1 |
secreted phosphoprotein 1 |
increases expression |
ISO |
Mycophenolic Acid results in increased expression of SPP1 mRNA |
CTD |
PMID:19818335 |
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NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162
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G |
Stat5a |
signal transducer and activator of transcription 5A |
multiple interactions |
ISO |
[Mycophenolic Acid co-treated with Imatinib Mesylate] results in decreased phosphorylation of STAT5A protein |
CTD |
PMID:15604220 |
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NCBI chr10:85,785,537...85,809,869
Ensembl chr10:85,785,537...85,809,866
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G |
Tgfb1 |
transforming growth factor, beta 1 |
decreases expression |
EXP |
Mycophenolic Acid results in decreased expression of TGFB1 mRNA |
CTD |
PMID:11562063 |
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NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
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G |
Thra |
thyroid hormone receptor alpha |
multiple interactions |
ISO |
Mycophenolic Acid binds to and results in decreased activity of THRA protein |
CTD |
PMID:25752796 |
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NCBI chr10:83,701,885...83,729,408
Ensembl chr10:83,700,755...83,729,936
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G |
Tjp1 |
tight junction protein 1 |
decreases expression multiple interactions |
ISO |
Mycophenolic Acid results in decreased expression of TJP1 protein schizandrin A inhibits the reaction [Mycophenolic Acid results in decreased expression of TJP1 protein] |
CTD |
PMID:35321622 |
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NCBI chr 1:118,849,838...119,094,492
Ensembl chr 1:118,849,838...119,094,432
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G |
Tnf |
tumor necrosis factor |
decreases expression multiple interactions increases expression |
EXP ISO |
Mycophenolic Acid results in decreased expression of TNF mRNA Mycophenolic Acid inhibits the reaction [Mercuric Chloride results in increased expression of TNF mRNA]; Mycophenolic Acid inhibits the reaction [Mercuric Chloride results in increased secretion of TNF protein] Mycophenolic Acid results in increased expression of TNF mRNA; Mycophenolic Acid results in increased expression of TNF protein |
CTD |
PMID:11562063 PMID:11912253 PMID:19818335 |
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NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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G |
Tnfrsf1a |
TNF receptor superfamily member 1A |
increases expression |
ISO |
Mycophenolic Acid results in increased expression of TNFRSF1A mRNA |
CTD |
PMID:19818335 |
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NCBI chr 4:158,150,815...158,163,592
Ensembl chr 4:158,150,820...158,163,591
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G |
Tnfrsf1b |
TNF receptor superfamily member 1B |
increases expression |
ISO |
Mycophenolic Acid results in increased expression of TNFRSF1B mRNA |
CTD |
PMID:19818335 |
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NCBI chr 5:157,070,642...157,104,216
Ensembl chr 5:157,070,642...157,104,206
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G |
Tp53 |
tumor protein p53 |
affects activity |
ISO |
Mycophenolic Acid affects the activity of TP53 protein |
CTD |
PMID:35435491 |
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NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
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G |
Tspoap1 |
TSPO associated protein 1 |
decreases expression |
ISO |
Mycophenolic Acid results in decreased expression of TSPOAP1 mRNA |
CTD |
PMID:24356939 |
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NCBI chr10:72,554,220...72,586,402
Ensembl chr10:72,560,980...72,586,412
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G |
Ugt1a9 |
UDP glucuronosyltransferase family 1 member A9 |
increases glucuronidation multiple interactions affects metabolic processing |
ISO |
UGT1A9 protein results in increased glucuronidation of Mycophenolic Acid 4-cresol inhibits the reaction [[UGT1A9 protein results in increased glucuronidation of Mycophenolic Acid] which results in increased abundance of mycophenolic acid glucuronide]; [4-cresol inhibits the reaction [[UGT1A9 protein results in increased glucuronidation of Mycophenolic Acid] which results in increased abundance of mycophenolic acid glucuronide]] which results in increased abundance of Mycophenolic Acid; [UGT1A9 protein results in increased glucuronidation of Mycophenolic Acid] which results in increased abundance of mycophenolic acid glucuronide UGT1A9 gene SNP affects the metabolism of Mycophenolic Acid |
CTD |
PMID:18498916 PMID:18816295 PMID:31742356 |
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NCBI chr 9:88,696,981...88,808,465
Ensembl chr 9:88,713,184...88,808,465
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G |
Cnr1 |
cannabinoid receptor 1 |
multiple interactions |
EXP |
N-oleoyldopamine binds to and results in increased activity of CNR1 protein |
CTD |
PMID:12569099 |
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NCBI chr 5:48,408,543...48,436,099
Ensembl chr 5:48,408,574...48,435,099
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G |
Col1a1 |
collagen type I alpha 1 chain |
multiple interactions |
ISO |
N-oleoyldopamine inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA] |
CTD |
PMID:27936102 |
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NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
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G |
Tgfb1 |
transforming growth factor, beta 1 |
multiple interactions |
ISO |
N-oleoyldopamine inhibits the reaction [TGFB1 protein results in increased expression of COL1A1 mRNA] |
CTD |
PMID:27936102 |
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NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
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G |
Trpv1 |
transient receptor potential cation channel, subfamily V, member 1 |
multiple interactions increases activity |
ISO EXP |
3-(4-t-butylphenyl)-N-(2,3-dihydrobenzo(b)(1,4)dioxin-6-yl)acrylamide inhibits the reaction [N-oleoyldopamine promotes the reaction [TRPV1 protein results in increased uptake of Calcium]]; [N-oleoyldopamine results in increased activity of TRPV1 protein] which results in increased uptake of Calcium; iodoresiniferatoxin inhibits the reaction [[N-oleoyldopamine results in increased activity of TRPV1 protein] which results in increased uptake of Calcium]; iodoresiniferatoxin inhibits the reaction [N-oleoyldopamine results in increased activity of TRPV1 protein] |
CTD |
PMID:12569099 PMID:15615864 |
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NCBI chr10:57,851,428...57,876,513
Ensembl chr10:57,851,428...57,876,513
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G |
Abca1 |
ATP binding cassette subfamily A member 1 |
multiple interactions increases expression increases phosphorylation increases degradation |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of ABCA1 mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of ABCA1 mRNA; Oleic Acid inhibits the reaction [APOA1 protein affects the reaction [ABCA1 protein results in increased transport of Cholesterol]]; Oleic Acid inhibits the reaction [APOA1 protein affects the reaction [ABCA1 protein results in increased transport of Phospholipids]] Oleic Acid results in increased expression of ABCA1 mRNA Oleic Acid results in increased phosphorylation of ABCA1 protein Oleic Acid results in increased degradation of ABCA1 protein Oleic Acid inhibits the reaction [27-hydroxycholesterol results in increased expression of ABCA1 mRNA] |
CTD |
PMID:16118212 PMID:18356535 PMID:30547786 |
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NCBI chr 5:67,678,267...67,801,162
Ensembl chr 5:67,681,297...67,801,170
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G |
Abcb11 |
ATP binding cassette subfamily B member 11 |
increases expression |
EXP |
Oleic Acid results in increased expression of ABCB11 mRNA |
CTD |
PMID:32738331 |
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NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730
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G |
Abcd3 |
ATP binding cassette subfamily D member 3 |
multiple interactions |
ISO |
PPARA protein promotes the reaction [Oleic Acid results in increased expression of ABCD3 mRNA] |
CTD |
PMID:18489776 |
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NCBI chr 2:209,852,087...209,905,763
Ensembl chr 2:209,852,087...209,906,020
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G |
Abcg1 |
ATP binding cassette subfamily G member 1 |
decreases expression |
ISO |
Oleic Acid results in decreased expression of ABCG1 mRNA; Oleic Acid results in decreased expression of ABCG1 protein |
CTD |
PMID:16730733 |
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NCBI chr20:9,126,687...9,182,948
Ensembl chr20:9,126,687...9,182,948
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G |
Abcg2 |
ATP binding cassette subfamily G member 2 |
increases expression |
ISO |
Oleic Acid results in increased expression of ABCG2 mRNA |
CTD |
PMID:22819932 |
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NCBI chr 4:87,676,241...87,802,757
Ensembl chr 4:87,745,319...87,802,409
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G |
Acaa1a |
acetyl-CoA acyltransferase 1A |
multiple interactions |
ISO |
[Farnesol analog co-treated with Oleic Acid] results in increased expression of ACAA1 mRNA; [GW 7647 co-treated with Oleic Acid] results in increased expression of ACAA1 mRNA |
CTD |
PMID:30611723 |
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NCBI chr 8:119,079,401...119,088,626
Ensembl chr 8:119,079,775...119,088,624
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G |
Acaa2 |
acetyl-CoA acyltransferase 2 |
multiple interactions increases expression |
ISO |
[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of ACAA2 mRNA; [Farnesol analog co-treated with Oleic Acid] results in increased expression of ACAA2 mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of ACAA2 mRNA; [GW 7647 co-treated with Oleic Acid] results in increased expression of ACAA2 mRNA Oleic Acid results in increased expression of ACAA2 mRNA |
CTD |
PMID:30611723 |
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NCBI chr18:68,345,136...68,373,246
Ensembl chr18:68,345,012...68,373,249
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G |
Acaca |
acetyl-CoA carboxylase alpha |
multiple interactions increases expression |
ISO |
[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in decreased expression of ACACA mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of ACACA mRNA; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of ACACA mRNA; cyhalothrin promotes the reaction [Oleic Acid results in increased expression of ACACA protein]; Escin inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in increased expression of ACACA mRNA] |
CTD |
PMID:30611723 PMID:36529352 PMID:36905866 |
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NCBI chr10:69,014,261...69,276,453
Ensembl chr10:69,014,170...69,276,457
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G |
Acacb |
acetyl-CoA carboxylase beta |
multiple interactions |
ISO |
[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in decreased expression of ACACB mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of ACACB mRNA |
CTD |
PMID:30611723 |
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NCBI chr12:42,365,800...42,477,651
Ensembl chr12:42,366,548...42,457,655
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G |
Acad9 |
acyl-CoA dehydrogenase family, member 9 |
multiple interactions increases expression |
ISO |
[Vehicle Emissions results in increased abundance of Particulate Matter] inhibits the reaction [Oleic Acid results in increased expression of ACAD9 mRNA] |
CTD |
PMID:31340670 |
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NCBI chr 2:118,943,170...118,966,150
Ensembl chr 2:118,943,174...118,966,547
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G |
Acadl |
acyl-CoA dehydrogenase, long chain |
multiple interactions |
ISO |
[GW 4064 co-treated with Oleic Acid] results in decreased expression of ACADL mRNA; [GW 7647 co-treated with Oleic Acid] results in decreased expression of ACADL mRNA |
CTD |
PMID:30611723 |
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NCBI chr 9:68,333,981...68,372,149
Ensembl chr 9:68,333,980...68,372,220
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G |
Acadm |
acyl-CoA dehydrogenase medium chain |
multiple interactions |
EXP ISO |
[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of ACADM mRNA; Bezafibrate inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of ACADM mRNA]; quercetin 3-O-glucuronide inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of ACADM mRNA] [Farnesol analog co-treated with Oleic Acid] results in increased expression of ACADM mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of ACADM mRNA |
CTD |
PMID:26190035 PMID:30611723 |
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NCBI chr 2:242,858,865...242,883,036
Ensembl chr 2:242,858,865...242,883,147
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G |
Acads |
acyl-CoA dehydrogenase short chain |
multiple interactions increases expression |
ISO |
[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of ACADS mRNA; [Farnesol analog co-treated with Oleic Acid] results in increased expression of ACADS mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of ACADS mRNA; [GW 7647 co-treated with Oleic Acid] results in increased expression of ACADS mRNA Oleic Acid results in increased expression of ACADS mRNA |
CTD |
PMID:30611723 |
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NCBI chr12:41,493,650...41,502,897
Ensembl chr12:41,493,626...41,502,898
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G |
Acadvl |
acyl-CoA dehydrogenase, very long chain |
multiple interactions |
ISO |
[GW 4064 co-treated with Oleic Acid] results in decreased expression of ACADVL mRNA; [GW 7647 co-treated with Oleic Acid] results in increased expression of ACADVL mRNA |
CTD |
PMID:30611723 |
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NCBI chr10:54,732,875...54,738,102
Ensembl chr10:54,732,469...54,738,075
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G |
Acat1 |
acetyl-CoA acetyltransferase 1 |
multiple interactions |
ISO |
[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of ACAT1 mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of ACAT1 mRNA |
CTD |
PMID:30611723 |
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NCBI chr 8:53,979,813...54,008,861
Ensembl chr 8:53,979,813...54,008,855
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G |
Acat2 |
acetyl-CoA acetyltransferase 2 |
multiple interactions |
ISO |
[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of ACAT2 mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of ACAT2 mRNA |
CTD |
PMID:30611723 |
|
NCBI chr 1:47,695,833...47,713,879
Ensembl chr 1:47,695,788...47,752,821
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G |
Acly |
ATP citrate lyase |
multiple interactions decreases expression |
ISO |
[[Vehicle Emissions results in increased abundance of Particulate Matter] which co-treated with Oleic Acid] results in decreased expression of ACLY mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of ACLY mRNA Oleic Acid results in decreased expression of ACLY mRNA |
CTD |
PMID:30611723 PMID:31340670 |
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NCBI chr10:85,412,045...85,464,253
Ensembl chr10:85,412,049...85,463,320
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G |
Acot1 |
acyl-CoA thioesterase 1 |
multiple interactions |
ISO |
[Farnesol analog co-treated with Oleic Acid] results in increased expression of ACOT1 mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of ACOT1 mRNA |
CTD |
PMID:30611723 |
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NCBI chr 6:103,636,173...103,644,167
Ensembl chr 6:103,636,041...103,644,163
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G |
Acot12 |
acyl-CoA thioesterase 12 |
multiple interactions increases expression |
ISO |
[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of ACOT12 mRNA; [Farnesol analog co-treated with Oleic Acid] results in increased expression of ACOT12 mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of ACOT12 mRNA; [GW 7647 co-treated with Oleic Acid] results in increased expression of ACOT12 mRNA Oleic Acid results in increased expression of ACOT12 mRNA |
CTD |
PMID:30611723 |
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NCBI chr 2:22,986,867...23,027,538
Ensembl chr 2:22,986,626...23,027,536
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G |
Acot4 |
acyl-CoA thioesterase 4 |
multiple interactions |
ISO |
[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of ACOT4 mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of ACOT4 mRNA; [GW 7647 co-treated with Oleic Acid] results in increased expression of ACOT4 mRNA |
CTD |
PMID:30611723 |
|
NCBI chr 6:103,668,699...103,674,037
Ensembl chr 6:103,668,753...103,673,917
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G |
Acot6 |
acyl-CoA thioesterase 6 |
multiple interactions |
ISO |
[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of ACOT6 mRNA; [Farnesol analog co-treated with Oleic Acid] results in decreased expression of ACOT6 mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of ACOT6 mRNA |
CTD |
PMID:30611723 |
|
NCBI chr 6:103,732,372...103,741,446
Ensembl chr 6:103,732,372...103,741,446
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G |
Acot7 |
acyl-CoA thioesterase 7 |
multiple interactions |
ISO |
[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of ACOT7 mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of ACOT7 mRNA |
CTD |
PMID:30611723 |
|
NCBI chr 5:162,686,562...162,779,309
Ensembl chr 5:162,684,645...162,779,309
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G |
Acot8 |
acyl-CoA thioesterase 8 |
multiple interactions |
ISO |
[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in decreased expression of ACOT8 mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of ACOT8 mRNA |
CTD |
PMID:30611723 |
|
NCBI chr 3:153,531,192...153,542,851
Ensembl chr 3:153,531,193...153,542,851
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G |
Acox1 |
acyl-CoA oxidase 1 |
multiple interactions |
ISO |
[Farnesol analog co-treated with Oleic Acid] results in increased expression of ACOX1 mRNA; [Fenofibrate co-treated with Oleic Acid] results in increased expression of ACOX1 mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of ACOX1 mRNA; [GW 7647 co-treated with Oleic Acid] results in increased expression of ACOX1 mRNA; [muraglitazar co-treated with Oleic Acid] results in increased expression of ACOX1 mRNA; [Palmitic Acid co-treated with Oleic Acid] results in decreased expression of ACOX1 mRNA; [Rosiglitazone co-treated with Oleic Acid] results in increased expression of ACOX1 mRNA; [tesaglitazar co-treated with Oleic Acid] results in increased expression of ACOX1 mRNA; Escin inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of ACOX1 mRNA] |
CTD |
PMID:24534255 PMID:30611723 PMID:36905866 |
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NCBI chr10:101,406,197...101,431,252
Ensembl chr10:101,406,197...101,431,232
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G |
Acox2 |
acyl-CoA oxidase 2 |
multiple interactions decreases expression |
ISO |
[GW 4064 co-treated with Oleic Acid] results in decreased expression of ACOX2 mRNA; [GW 7647 co-treated with Oleic Acid] results in decreased expression of ACOX2 mRNA Oleic Acid results in decreased expression of ACOX2 mRNA |
CTD |
PMID:30611723 |
|
NCBI chr15:16,660,584...16,692,160
Ensembl chr15:16,660,272...16,692,160
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G |
Acsl1 |
acyl-CoA synthetase long-chain family member 1 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of ACSL1 mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of ACSL1 mRNA |
CTD |
PMID:30547786 |
|
NCBI chr16:45,755,246...45,821,541
Ensembl chr16:45,755,254...45,821,541
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G |
Acsl3 |
acyl-CoA synthetase long-chain family member 3 |
multiple interactions |
ISO |
[GW 4064 co-treated with Oleic Acid] results in decreased expression of ACSL3 mRNA |
CTD |
PMID:30611723 |
|
NCBI chr 9:80,115,164...80,164,636
Ensembl chr 9:80,115,112...80,164,627
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G |
Acsl4 |
acyl-CoA synthetase long-chain family member 4 |
multiple interactions |
ISO |
[Farnesol analog co-treated with Oleic Acid] results in increased expression of ACSL4 mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of ACSL4 mRNA; [GW 7647 co-treated with Oleic Acid] results in increased expression of ACSL4 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of ACSL4 mRNA |
CTD |
PMID:30547786 PMID:30611723 |
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NCBI chr X:105,942,794...106,006,573
Ensembl chr X:105,942,799...106,006,427
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G |
Acsl5 |
acyl-CoA synthetase long-chain family member 5 |
multiple interactions |
ISO |
[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of ACSL5 mRNA; [Farnesol analog co-treated with Oleic Acid] results in increased expression of ACSL5 mRNA; [GW 7647 co-treated with Oleic Acid] results in increased expression of ACSL5 mRNA |
CTD |
PMID:30611723 |
|
NCBI chr 1:254,289,513...254,336,608
Ensembl chr 1:254,292,521...254,336,607
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G |
Acta2 |
actin alpha 2, smooth muscle |
multiple interactions increases expression |
ISO |
[Oleic Acid co-treated with Palmitic Acid] results in increased expression of ACTA2 mRNA Oleic Acid results in increased expression of ACTA2 mRNA |
CTD |
PMID:26187275 PMID:32918399 |
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NCBI chr 1:231,746,527...231,759,307
Ensembl chr 1:231,746,548...231,759,554
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G |
Adipoq |
adiponectin, C1Q and collagen domain containing |
decreases expression multiple interactions |
EXP |
Oleic Acid results in decreased expression of ADIPOQ mRNA sophocarpine inhibits the reaction [Oleic Acid results in decreased expression of ADIPOQ mRNA] |
CTD |
PMID:23395669 |
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NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564
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G |
Adipor2 |
adiponectin receptor 2 |
decreases expression |
EXP |
oleic acid cotreated with ethanol decreases expression of adipor2 mRNA in rat primary hepatocytes |
RGD |
PMID:21194380 |
RGD:24922202 |
NCBI chr 4:152,524,604...152,588,848
Ensembl chr 4:152,524,623...152,559,355
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G |
Agpat1 |
1-acylglycerol-3-phosphate O-acyltransferase 1 |
multiple interactions |
ISO |
[Farnesol analog co-treated with Oleic Acid] results in decreased expression of AGPAT1 mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of AGPAT1 mRNA |
CTD |
PMID:30611723 |
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NCBI chr20:4,135,955...4,144,880
Ensembl chr20:4,135,957...4,145,278
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G |
Agpat2 |
1-acylglycerol-3-phosphate O-acyltransferase 2 |
increases expression multiple interactions |
ISO |
Oleic Acid results in increased expression of AGPAT2 mRNA [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of AGPAT2 mRNA; [GW 7647 co-treated with Oleic Acid] results in increased expression of AGPAT2 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of AGPAT2 mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of AGPAT2 mRNA |
CTD |
PMID:30547786 PMID:30611723 |
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NCBI chr 3:9,416,837...9,428,567
Ensembl chr 3:9,416,843...9,428,371
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G |
Agpat5 |
1-acylglycerol-3-phosphate O-acyltransferase 5 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of AGPAT5 mRNA |
CTD |
PMID:30547786 |
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NCBI chr16:70,939,480...70,985,745
Ensembl chr16:70,943,135...70,985,560
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G |
Ahr |
aryl hydrocarbon receptor |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of AHR mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of AHR mRNA |
CTD |
PMID:30547786 |
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NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
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G |
Akt1 |
AKT serine/threonine kinase 1 |
multiple interactions decreases phosphorylation |
EXP ISO |
Oleic Acid inhibits the reaction [IRS2 results in increased phosphorylation of and results in increased activity of AKT1 protein] [Oleic Acid co-treated with Palmitic Acid] results in decreased phosphorylation of AKT1 protein 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Oleic Acid results in decreased phosphorylation of AKT1 protein]]; 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [NAD inhibits the reaction [Oleic Acid results in decreased phosphorylation of AKT1 protein]]; [N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride co-treated with NAD] inhibits the reaction [Oleic Acid results in decreased phosphorylation of AKT1 protein]; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Oleic Acid results in decreased phosphorylation of AKT1 protein]; NAD inhibits the reaction [Oleic Acid results in decreased phosphorylation of AKT1 protein]; PARP1 protein affects the reaction [Oleic Acid results in decreased phosphorylation of AKT1 protein] |
CTD |
PMID:14604813 PMID:25536389 PMID:26847930 |
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NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
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G |
Alb |
albumin |
multiple interactions affects binding decreases secretion |
ISO |
[ALB protein binds to Oleic Acid] promotes the reaction [ALB protein results in increased reduction of Dithionitrobenzoic Acid]; [ALB protein binds to Oleic Acid] promotes the reaction [Pyruvaldehyde results in increased oxidation of ALB protein]; [ALB protein modified form binds to Oleic Acid] which results in decreased reduction of Dithionitrobenzoic Acid; [Oleic Acid co-treated with muraglitazar] results in increased expression of ALB mRNA; [Oleic Acid co-treated with Palmitic Acid] results in increased expression of ALB protein; [Oleic Acid co-treated with Rosiglitazone] results in increased expression of ALB mRNA; [Oleic Acid co-treated with tesaglitazar] results in increased expression of ALB mRNA; Coptidis rhizoma extract inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of ALB protein]; Quercetin inhibits the reaction [Oleic Acid results in decreased secretion of ALB protein]; Silymarin inhibits the reaction [Oleic Acid results in decreased secretion of ALB protein]; Vitamin E inhibits the reaction [Oleic Acid results in decreased secretion of ALB protein] |
CTD |
PMID:23348005 PMID:24534255 PMID:25451573 PMID:38103844 |
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NCBI chr14:17,607,397...17,622,814
Ensembl chr14:17,607,381...17,622,836
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G |
Aldh1a1 |
aldehyde dehydrogenase 1 family, member A1 |
decreases expression |
ISO |
Oleic Acid results in decreased expression of ALDH1A1 mRNA |
CTD |
PMID:26739624 |
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NCBI chr 1:218,000,470...218,152,962
Ensembl chr 1:218,042,127...218,152,961
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G |
Angptl4 |
angiopoietin-like 4 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of ANGPTL4 mRNA; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of ANGPTL4 mRNA |
CTD |
PMID:30547786 |
|
NCBI chr 7:14,550,288...14,557,797
Ensembl chr 7:14,550,311...14,556,519
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G |
Anxa2 |
annexin A2 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of ANXA2 mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of ANXA2 mRNA |
CTD |
PMID:30547786 |
|
NCBI chr 8:70,105,268...70,141,663
Ensembl chr 8:70,105,253...70,141,658
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G |
Apoa1 |
apolipoprotein A1 |
multiple interactions |
ISO |
Oleic Acid inhibits the reaction [APOA1 protein affects the reaction [ABCA1 protein results in increased transport of Cholesterol]]; Oleic Acid inhibits the reaction [APOA1 protein affects the reaction [ABCA1 protein results in increased transport of Phospholipids]] |
CTD |
PMID:16118212 |
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NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035
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G |
Apoa4 |
apolipoprotein A4 |
increases expression |
ISO |
Oleic Acid results in increased expression of APOA4 mRNA |
CTD |
PMID:26739624 |
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NCBI chr 8:46,539,083...46,541,464
Ensembl chr 8:46,539,082...46,541,469
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G |
Apoa5 |
apolipoprotein A5 |
increases expression multiple interactions |
ISO |
Oleic Acid results in increased expression of APOA5 mRNA [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of APOA5 mRNA; [Farnesol analog co-treated with Oleic Acid] results in increased expression of APOA5 mRNA; [GW 4064 co-treated with Oleic Acid] results in increased expression of APOA5 mRNA; [GW 7647 co-treated with Oleic Acid] results in increased expression of APOA5 mRNA |
CTD |
PMID:30611723 |
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NCBI chr 8:46,561,180...46,563,818
Ensembl chr 8:46,561,229...46,563,816
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G |
Apob |
apolipoprotein B |
multiple interactions decreases expression increases expression |
ISO EXP |
[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in decreased expression of APOB mRNA; [Eicosapentaenoic Acid co-treated with Docosahexaenoic Acids co-treated with Oleic Acid co-treated with Folic Acid co-treated with Vitamin B 6 co-treated with Vitamin E] results in decreased expression of APOB protein; [GW 4064 co-treated with Oleic Acid] results in decreased expression of APOB mRNA; [GW 7647 co-treated with Oleic Acid] results in decreased expression of APOB mRNA; Bezafibrate inhibits the reaction [Oleic Acid results in increased expression of APOB protein]; Oleic Acid inhibits the reaction [Glucosamine results in decreased secretion of APOB protein]; Oleic Acid results in increased expression of and results in increased secretion of APOB protein Oleic Acid results in decreased expression of APOB mRNA [Oleic Acid co-treated with Palmitic Acid] results in increased expression of APOB mRNA; Ethanol inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of APOB mRNA]; Oleic Acid inhibits the reaction [Glucosamine results in increased degradation of APOB protein] |
CTD |
PMID:12048068 PMID:15618547 PMID:17237316 PMID:19383982 PMID:26854922 PMID:30611723 PMID:32918399 More...
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NCBI chr 6:30,844,386...30,883,983
Ensembl chr 6:30,844,368...30,892,497
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G |
Apoc3 |
apolipoprotein C3 |
multiple interactions |
ISO |
[Oleic Acid co-treated with muraglitazar] results in increased expression of APOC3 mRNA; [Oleic Acid co-treated with rosiglitazone] results in increased expression of APOC3 mRNA; [Oleic Acid co-treated with tesaglitazar] results in increased expression of APOC3 mRNA |
CTD |
PMID:24534255 |
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NCBI chr 8:46,531,478...46,533,658
Ensembl chr 8:46,531,478...46,533,583
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G |
Apoc4 |
apolipoprotein C4 |
multiple interactions |
ISO |
[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in decreased expression of APOC4 mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of APOC4 mRNA; [GW 7647 co-treated with Oleic Acid] results in decreased expression of APOC4 mRNA |
CTD |
PMID:30611723 |
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NCBI chr 1:79,335,745...79,339,942
Ensembl chr 1:79,335,745...79,339,981
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G |
Apoe |
apolipoprotein E |
multiple interactions |
ISO |
[GW 4064 co-treated with Oleic Acid] results in decreased expression of APOE mRNA; [GW 7647 co-treated with Oleic Acid] results in decreased expression of APOE mRNA |
CTD |
PMID:30611723 |
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NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932
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G |
Arg1 |
arginase 1 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of ARG1 mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of ARG1 mRNA |
CTD |
PMID:30547786 |
|
NCBI chr 1:20,475,878...20,488,422
Ensembl chr 1:20,475,968...20,488,422
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G |
Atf6 |
activating transcription factor 6 |
multiple interactions |
ISO |
3-N-1(spermine)-7, 24-dihydroxy-5-cholestane 24-sulfate inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in increased expression of ATF6 mRNA]; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of ATF6 mRNA Oleic Acid inhibits the reaction [[Palmitates co-treated with bisphenol A] results in increased expression of ATF6 mRNA] |
CTD |
PMID:32369900 PMID:32976987 |
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NCBI chr13:82,927,579...83,106,381
Ensembl chr13:82,930,034...83,107,177
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G |
Atg5 |
autophagy related 5 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of ATG5 protein; Escin inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of ATG5 protein] |
CTD |
PMID:36905866 |
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NCBI chr20:47,798,217...47,889,216
Ensembl chr20:47,798,290...47,889,209
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G |
Atg7 |
autophagy related 7 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of ATG7 protein; Escin inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of ATG7 protein] |
CTD |
PMID:36905866 |
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NCBI chr 4:147,718,663...147,925,656
Ensembl chr 4:147,718,752...147,925,593
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G |
B4galt5 |
beta-1,4-galactosyltransferase 5 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of B4GALT5 mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of B4GALT5 mRNA |
CTD |
PMID:30547786 |
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NCBI chr 3:156,018,056...156,033,983
Ensembl chr 3:156,018,053...156,070,074
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G |
Bace1 |
beta-secretase 1 |
multiple interactions |
ISO |
[Oleic Acid co-treated with Palmitic Acid] results in increased expression of BACE1 mRNA; [Oleic Acid co-treated with Palmitic Acid] results in increased expression of BACE1 protein; BACE1 protein affects the reaction [SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of DDIT3 protein]]; BACE1 protein affects the reaction [SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of HSPA5 protein]]; BACE1 protein affects the reaction [SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of IL1B protein]]; BACE1 protein affects the reaction [SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of IL6 protein]]; BACE1 protein affects the reaction [SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of TNF protein]]; MIR497 affects the reaction [SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of BACE1 protein]]; SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of BACE1 protein] |
CTD |
PMID:37009739 |
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NCBI chr 8:46,142,060...46,166,268
Ensembl chr 8:46,142,116...46,165,876
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G |
Bax |
BCL2 associated X, apoptosis regulator |
multiple interactions |
ISO |
3-N-1(spermine)-7, 24-dihydroxy-5-cholestane 24-sulfate inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in increased expression of BAX mRNA]; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of BAX mRNA |
CTD |
PMID:32369900 |
|
NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
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G |
Bcl2 |
BCL2, apoptosis regulator |
multiple interactions |
ISO |
3-N-1(spermine)-7, 24-dihydroxy-5-cholestane 24-sulfate inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of BCL2 mRNA]; [Palmitic Acid co-treated with Oleic Acid] results in decreased expression of BCL2 mRNA |
CTD |
PMID:32369900 |
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NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
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G |
Casp3 |
caspase 3 |
multiple interactions increases cleavage |
ISO |
3-N-1(spermine)-7, 24-dihydroxy-5-cholestane 24-sulfate inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in increased expression of CASP3 mRNA]; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of CASP3 mRNA Oleic Acid results in increased cleavage of CASP3 protein Oleic Acid inhibits the reaction [[Palmitates co-treated with bisphenol A] results in increased cleavage of CASP3 protein] |
CTD |
PMID:32369900 PMID:32976987 PMID:36273635 |
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NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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G |
Casp9 |
caspase 9 |
multiple interactions increases cleavage |
EXP ISO |
IRS2 inhibits the reaction [Oleic Acid results in increased cleavage of CASP9 protein] 3-N-1(spermine)-7, 24-dihydroxy-5-cholestane 24-sulfate inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in increased expression of CASP9 mRNA]; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of CASP9 mRNA |
CTD |
PMID:14604813 PMID:32369900 |
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NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
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G |
Cat |
catalase |
multiple interactions increases activity decreases activity |
ISO EXP |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of CAT mRNA; Quercetin inhibits the reaction [Oleic Acid results in decreased activity of CAT protein]; Silymarin inhibits the reaction [Oleic Acid results in decreased activity of CAT protein]; Vitamin E inhibits the reaction [Oleic Acid results in decreased activity of CAT protein] Oleic Acid results in increased activity of CAT protein [Oleic Acid co-treated with Palmitic Acid co-treated with Ethanol] results in increased activity of CAT protein; [Oleic Acid co-treated with Palmitic Acid] results in increased activity of CAT protein; Dexamethasone inhibits the reaction [Oleic Acid results in increased activity of CAT protein]; gossypin inhibits the reaction [Oleic Acid results in increased activity of CAT protein] |
CTD |
PMID:23348005 PMID:26854922 PMID:30547786 PMID:37696682 |
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NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
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G |
Cav2 |
caveolin 2 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid] affects the expression of CAV2 mRNA |
CTD |
PMID:30547786 |
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NCBI chr 4:45,616,766...45,624,144
Ensembl chr 4:45,616,712...45,624,244
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G |
Cd36 |
CD36 molecule |
multiple interactions increases expression |
ISO EXP |
GW 4064 inhibits the reaction [Oleic Acid results in increased expression of CD36 protein] Oleic Acid results in increased expression of CD36 mRNA [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of CD36 mRNA; [GW 4064 co-treated with Oleic Acid] results in increased expression of CD36 mRNA; [GW 7647 co-treated with Oleic Acid] results in increased expression of CD36 mRNA; [Oleic Acid co-treated with Palmitic Acid] results in increased expression of CD36 mRNA; Coptidis rhizoma extract inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of CD36 mRNA]; isosilybin inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of CD36 mRNA] [Oleic Acid co-treated with Linoleic Acid] results in increased expression of CD36 mRNA |
CTD |
PMID:23371517 PMID:28552552 PMID:30611723 PMID:36347319 PMID:38092172 PMID:38103844 More...
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NCBI chr 4:17,317,343...17,410,084
Ensembl chr 4:17,354,466...17,513,903
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G |
Cdkn1a |
cyclin-dependent kinase inhibitor 1A |
multiple interactions |
ISO |
3-N-1(spermine)-7, 24-dihydroxy-5-cholestane 24-sulfate inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in increased expression of CDKN1A mRNA]; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of CDKN1A mRNA |
CTD |
PMID:32369900 |
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NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
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G |
Cidec |
cell death-inducing DFFA-like effector c |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of CIDEC protein; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of CIDEC mRNA |
CTD |
PMID:30547786 |
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NCBI chr 4:146,569,288...146,582,173
Ensembl chr 4:146,569,289...146,582,173
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G |
Col1a1 |
collagen type I alpha 1 chain |
multiple interactions increases expression |
ISO |
[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of COL1A1 mRNA; Sorafenib inhibits the reaction [Oleic Acid results in increased expression of COL1A1 mRNA] |
CTD |
PMID:26187275 PMID:32918399 |
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NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
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G |
Cox10 |
cytochrome c oxidase assembly factor heme A:farnesyltransferase COX10 |
multiple interactions |
ISO |
[GW 4064 co-treated with Oleic Acid] results in decreased expression of COX10 mRNA |
CTD |
PMID:30611723 |
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NCBI chr10:48,630,993...48,742,805
Ensembl chr10:48,630,676...48,746,667
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G |
Cpt1a |
carnitine palmitoyltransferase 1A |
increases expression decreases expression multiple interactions |
EXP ISO |
Oleic Acid results in increased expression of CPT1A mRNA Oleic Acid results in decreased expression of CPT1A mRNA [Starch co-treated with Oleic Acid] results in increased expression of CPT1A mRNA; [Sucrose co-treated with Oleic Acid] results in increased expression of CPT1A mRNA [Oleic Acid co-treated with Palmitic Acid] results in decreased expression of CPT1A mRNA; [Oleic Acid co-treated with Palmitic Acid] results in increased expression of CPT1A mRNA; [Oleic Acid co-treated with Palmitic Acid] results in increased expression of CPT1A protein; Bezafibrate inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of CPT1A mRNA]; Ethanol inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of CPT1A protein]; quercetin 3-O-glucuronide inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of CPT1A mRNA]; tetrabromobisphenol A promotes the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of CPT1A mRNA]; Triiodothyronine promotes the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of CPT1A mRNA] [Farnesol analog co-treated with Oleic Acid] results in increased expression of CPT1A mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of CPT1A mRNA; [GW 7647 co-treated with Oleic Acid] results in increased expression of CPT1A mRNA; [Oleic Acid co-treated with Palmitic Acid] results in increased expression of CPT1A mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in decreased expression of CPT1A protein; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of CPT1A mRNA; [Palmitic Acid co-treated with Oleic Acid] results in decreased expression of CPT1A protein; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of CPT1A mRNA; Bezafibrate promotes the reaction [Oleic Acid results in increased expression of CPT1A mRNA]; Fenofibrate promotes the reaction [Oleic Acid results in increased expression of CPT1A mRNA]; isosilybin promotes the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of CPT1A mRNA]; muraglitazar promotes the reaction [Oleic Acid results in increased expression of CPT1A mRNA]; Rosiglitazone promotes the reaction [Oleic Acid results in increased expression of CPT1A mRNA]; Sorafenib inhibits the reaction [Oleic Acid results in decreased expression of CPT1A mRNA]; tesaglitazar promotes the reaction [Oleic Acid results in increased expression of CPT1A mRNA] |
CTD |
PMID:11171094 PMID:24534255 PMID:25048947 PMID:26190035 PMID:26854922 PMID:26895660 PMID:30547786 PMID:30611723 PMID:32918399 PMID:36347319 More...
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NCBI chr 1:200,564,634...200,627,059
Ensembl chr 1:200,565,613...200,627,055
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G |
Cpt2 |
carnitine palmitoyltransferase 2 |
multiple interactions |
ISO |
[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in decreased expression of CPT2 mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of CPT2 mRNA; [GW 7647 co-treated with Oleic Acid] results in increased expression of CPT2 mRNA; [muraglitazar co-treated with Oleic Acid] results in increased expression of CPT2 mRNA; [Oleic Acid co-treated with Bezafibrate] results in increased expression of CPT2 mRNA; [Oleic Acid co-treated with Fenofibrate] results in increased expression of CPT2 mRNA; [Oleic Acid co-treated with tesaglitazar] results in increased expression of CPT2 mRNA; [Palmitic Acid co-treated with Oleic Acid] results in decreased expression of CPT2 mRNA; [Rosiglitazone co-treated with Oleic Acid] results in increased expression of CPT2 mRNA; Escin inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of CPT2 mRNA] |
CTD |
PMID:24534255 PMID:30611723 PMID:36905866 |
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NCBI chr 5:122,664,677...122,682,126
Ensembl chr 5:122,664,677...122,682,095
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G |
Crebbp |
CREB binding protein |
decreases expression |
EXP |
Oleic Acid results in decreased expression of CREBBP mRNA |
CTD |
PMID:24349266 |
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NCBI chr10:11,335,551...11,461,888
Ensembl chr10:11,335,953...11,461,888
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G |
Crp |
C-reactive protein |
multiple interactions |
ISO |
[Eicosapentaenoic Acid co-treated with Docosahexaenoic Acids co-treated with Oleic Acid co-treated with Folic Acid co-treated with Vitamin B 6 co-treated with Vitamin E] results in decreased expression of CRP protein |
CTD |
PMID:17237316 |
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NCBI chr13:85,135,384...85,175,178
Ensembl chr13:85,124,977...85,175,178
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G |
Cxcl10 |
C-X-C motif chemokine ligand 10 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid] affects the expression of CXCL10 mRNA |
CTD |
PMID:30547786 |
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NCBI chr14:15,704,772...15,706,969
Ensembl chr14:15,704,758...15,706,975
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G |
Cxcl2 |
C-X-C motif chemokine ligand 2 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of CXCL2 mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of CXCL2 mRNA |
CTD |
PMID:30547786 |
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NCBI chr14:17,181,030...17,183,075
Ensembl chr14:17,181,062...17,183,075
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G |
Cycs |
cytochrome c, somatic |
multiple interactions |
ISO |
[Oleic Acid co-treated with anastrozole] affects the localization of CYCS protein; [Oleic Acid co-treated with letrozole] affects the localization of CYCS protein; [Oleic Acid co-treated with Linoleic Acid] results in increased expression of CYCS protein |
CTD |
PMID:24161488 PMID:27016407 |
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NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054 Ensembl chr18:79,651,378...79,654,054
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G |
Cyp1a1 |
cytochrome P450, family 1, subfamily a, polypeptide 1 |
increases expression multiple interactions |
ISO |
Oleic Acid results in increased expression of CYP1A1 mRNA; Oleic Acid results in increased expression of CYP1A1 protein [Estradiol co-treated with Benzo(a)pyrene] promotes the reaction [Oleic Acid results in increased expression of CYP1A1 mRNA]; [Estradiol co-treated with Benzo(a)pyrene] promotes the reaction [Oleic Acid results in increased expression of CYP1A1 protein] |
CTD |
PMID:31730885 |
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NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
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G |
Cyp1a2 |
cytochrome P450, family 1, subfamily a, polypeptide 2 |
decreases expression multiple interactions |
ISO |
Oleic Acid results in decreased expression of CYP1A2 mRNA Farnesol analog inhibits the reaction [Oleic Acid results in decreased expression of CYP1A2 mRNA] |
CTD |
PMID:30611723 |
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NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
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G |
Cyp24a1 |
cytochrome P450, family 24, subfamily a, polypeptide 1 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of CYP24A1 mRNA; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of CYP24A1 mRNA |
CTD |
PMID:30547786 |
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NCBI chr 3:159,275,947...159,290,383
Ensembl chr 3:159,275,947...159,290,383
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G |
Cyp26a1 |
cytochrome P450, family 26, subfamily a, polypeptide 1 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of CYP26A1 mRNA; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of CYP26A1 mRNA |
CTD |
PMID:30547786 |
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NCBI chr 1:235,471,368...235,475,204
Ensembl chr 1:235,471,298...235,475,204
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G |
Cyp26b1 |
cytochrome P450, family 26, subfamily b, polypeptide 1 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid] results in increased expression of CYP26B1 mRNA |
CTD |
PMID:30547786 |
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NCBI chr 4:117,041,808...117,058,628
Ensembl chr 4:117,041,808...117,058,628
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G |
Cyp2b3 |
cytochrome P450, family 2, subfamily b, polypeptide 3 |
multiple interactions decreases expression |
ISO |
[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of CYP2B6 mRNA; [Farnesol analog co-treated with Oleic Acid] results in increased expression of CYP2B6 mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of CYP2B6 mRNA; [GW 7647 co-treated with Oleic Acid] results in decreased expression of CYP2B6 mRNA; [Oleic Acid co-treated with Rosiglitazone] results in increased expression of CYP2B6 mRNA; [Oleic Acid co-treated with Troglitazone] results in increased expression of CYP2B6 mRNA; Farnesol analog inhibits the reaction [Oleic Acid results in decreased expression of CYP2B6 mRNA] |
CTD |
PMID:24534255 PMID:30611723 |
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NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143
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G |
Cyp2e1 |
cytochrome P450, family 2, subfamily e, polypeptide 1 |
multiple interactions increases expression |
EXP ISO |
[Oleic Acid co-treated with Palmitic Acid] inhibits the reaction [Ethanol results in increased expression of CYP2E1 mRNA]; [Oleic Acid co-treated with Palmitic Acid] results in increased expression of CYP2E1 mRNA; Ethanol inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of CYP2E1 mRNA] Oleic Acid results in increased expression of CYP2E1 mRNA [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of CYP2E1 mRNA; [Farnesol analog co-treated with Oleic Acid] results in increased expression of CYP2E1 mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of CYP2E1 mRNA; Farnesol analog inhibits the reaction [Oleic Acid results in increased expression of CYP2E1 mRNA] |
CTD |
PMID:26854922 PMID:30611723 |
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NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
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G |
Cyp3a2 |
cytochrome P450, family 3, subfamily a, polypeptide 2 |
multiple interactions decreases expression |
ISO |
Farnesol analog inhibits the reaction [Oleic Acid results in decreased expression of CYP3A4 mRNA] Oleic Acid results in decreased expression of CYP3A4 mRNA; Oleic Acid results in decreased expression of CYP3A4 protein |
CTD |
PMID:26739624 PMID:30611723 |
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NCBI chr12:9,207,978...9,230,064
Ensembl chr12:9,015,383...9,285,008
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G |
Cyp4a1 |
cytochrome P450, family 4, subfamily a, polypeptide 1 |
multiple interactions |
EXP |
[Oleic Acid co-treated with Palmitic Acid co-treated with Ethanol] results in decreased expression of CYP4A1 mRNA |
CTD |
PMID:26854922 |
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NCBI chr 5:129,123,323...129,137,464
Ensembl chr 5:129,123,336...129,137,464
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G |
Cyp4f6 |
cytochrome P450, family 4, subfamily f, polypeptide 6 |
multiple interactions |
ISO |
PPARA protein promotes the reaction [Oleic Acid results in increased expression of CYP4F16 mRNA] |
CTD |
PMID:18489776 |
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NCBI chr 7:12,030,276...12,058,020
Ensembl chr 7:12,030,301...12,057,782
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G |
Cyp7a1 |
cytochrome P450 family 7 subfamily A member 1 |
decreases expression multiple interactions |
EXP ISO |
Oleic Acid results in decreased expression of CYP7A1 mRNA [Oleic Acid co-treated with Palmitic Acid] results in increased expression of CYP7A1 mRNA; Coptidis rhizoma extract inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of CYP7A1 mRNA] |
CTD |
PMID:32738331 PMID:38103844 |
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NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688
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G |
Ddit3 |
DNA-damage inducible transcript 3 |
multiple interactions |
ISO |
3-N-1(spermine)-7, 24-dihydroxy-5-cholestane 24-sulfate inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in increased expression of DDIT3 mRNA]; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of DDIT3 mRNA [Oleic Acid co-treated with Palmitic Acid] results in increased expression of DDIT3 protein; BACE1 protein affects the reaction [SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of DDIT3 protein]]; MIR497 affects the reaction [SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of DDIT3 protein]]; Oleic Acid inhibits the reaction [[Palmitates co-treated with bisphenol A] results in increased expression of DDIT3 mRNA]; Oleic Acid inhibits the reaction [[Palmitates co-treated with bisphenol A] results in increased expression of DDIT3 protein]; SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of DDIT3 protein] |
CTD |
PMID:32369900 PMID:32976987 PMID:37009739 |
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NCBI chr 7:63,115,645...63,121,203
Ensembl chr 7:63,116,380...63,121,201
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G |
Decr1 |
2,4-dienoyl-CoA reductase 1 |
multiple interactions |
ISO |
[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of DECR1 mRNA; [Farnesol analog co-treated with Oleic Acid] results in decreased expression of DECR1 mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of DECR1 mRNA |
CTD |
PMID:30611723 |
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NCBI chr 5:29,411,172...29,439,054
Ensembl chr 5:29,411,172...29,439,018
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G |
Derl1 |
derlin 1 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid] affects the expression of DERL1 mRNA |
CTD |
PMID:30547786 |
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NCBI chr 7:89,404,413...89,427,095
Ensembl chr 7:89,404,417...89,427,145
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G |
Dgat1 |
diacylglycerol O-acyltransferase 1 |
multiple interactions |
ISO |
[GW 4064 co-treated with Oleic Acid] results in decreased expression of DGAT1 mRNA |
CTD |
PMID:30611723 |
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NCBI chr 7:108,223,860...108,235,413
Ensembl chr 7:108,218,524...108,234,299
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G |
Dgat2 |
diacylglycerol O-acyltransferase 2 |
multiple interactions |
ISO |
[Farnesol analog co-treated with Oleic Acid] results in increased expression of DGAT2 mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of DGAT2 mRNA; [Oleic Acid co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of DGAT2 mRNA; [Oleic Acid co-treated with Palmitic Acid] results in decreased expression of DGAT2 mRNA |
CTD |
PMID:30611723 PMID:38092172 |
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NCBI chr 1:153,454,078...153,484,432
Ensembl chr 1:153,454,080...153,484,428
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G |
Dhdds |
dehydrodolichyl diphosphate synthase subunit |
multiple interactions |
ISO |
[GW 4064 co-treated with Oleic Acid] results in decreased expression of DHDDS mRNA; [GW 7647 co-treated with Oleic Acid] results in increased expression of DHDDS mRNA |
CTD |
PMID:30611723 |
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NCBI chr 5:146,198,359...146,224,479
Ensembl chr 5:146,197,457...146,224,454
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G |
Dnm1l |
dynamin 1-like |
affects phosphorylation |
ISO |
Oleic Acid affects the phosphorylation of DNM1L protein |
CTD |
PMID:36273635 |
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NCBI chr11:84,581,216...84,632,382
Ensembl chr11:84,581,216...84,631,482
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G |
Dst |
dystonin |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in decreased expression of DST mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of DST mRNA |
CTD |
PMID:30547786 |
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NCBI chr 9:36,135,657...36,529,617
Ensembl chr 9:36,135,284...36,529,615
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G |
Dync1h1 |
dynein cytoplasmic 1 heavy chain 1 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of DYNC1H1 mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of DYNC1H1 mRNA |
CTD |
PMID:30547786 |
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NCBI chr 6:129,615,208...129,680,888
Ensembl chr 6:129,609,397...129,680,883
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G |
Dync1i1 |
dynein cytoplasmic 1 intermediate chain 1 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of DYNC1I1 mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of DYNC1I1 mRNA |
CTD |
PMID:30547786 |
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NCBI chr 4:33,852,597...34,166,159
Ensembl chr 4:33,852,927...34,166,149
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G |
E2f1 |
E2F transcription factor 1 |
decreases expression |
ISO |
Oleic Acid results in decreased expression of E2F1 protein |
CTD |
PMID:16027227 |
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NCBI chr 3:143,064,535...143,075,362
Ensembl chr 3:143,049,478...143,075,361
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G |
Ech1 |
enoyl-CoA hydratase 1 |
multiple interactions |
ISO |
[GW 4064 co-treated with Oleic Acid] results in decreased expression of ECH1 mRNA; [Oleic Acid co-treated with muraglitazar] results in increased expression of ECH1 mRNA; [Oleic Acid co-treated with Rosiglitazone] results in increased expression of ECH1 mRNA; [Oleic Acid co-treated with tesaglitazar] results in increased expression of ECH1 mRNA; [Oleic Acid co-treated with Troglitazone] results in increased expression of ECH1 mRNA |
CTD |
PMID:24534255 PMID:30611723 |
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NCBI chr 1:84,114,494...84,120,788
Ensembl chr 1:84,112,751...84,120,795
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G |
Echs1 |
enoyl-CoA hydratase, short chain 1 |
multiple interactions |
ISO |
[GW 4064 co-treated with Oleic Acid] results in decreased expression of ECHS1 mRNA |
CTD |
PMID:30611723 |
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NCBI chr 1:194,895,036...194,903,863
Ensembl chr 1:194,895,036...194,903,884
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G |
Edn1 |
endothelin 1 |
decreases expression |
ISO |
Oleic Acid results in decreased expression of EDN1 mRNA; Oleic Acid results in decreased expression of EDN1 protein |
CTD |
PMID:16895544 |
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NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885
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G |
Egfr |
epidermal growth factor receptor |
multiple interactions increases phosphorylation |
ISO |
[Oleic Acid co-treated with Palmitic Acid] results in increased expression of EGFR protein; [Palmitic Acid co-treated with Oleic Acid] affects the expression of EGFR mRNA; Coptidis rhizoma extract inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of EGFR protein] Oleic Acid results in increased phosphorylation of EGFR protein |
CTD |
PMID:27447558 PMID:30547786 PMID:38103844 |
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NCBI chr14:91,176,979...91,349,722
Ensembl chr14:91,177,067...91,344,382
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G |
Ehhadh |
enoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase |
multiple interactions |
ISO |
[GW 4064 co-treated with Oleic Acid] results in decreased expression of EHHADH mRNA |
CTD |
PMID:30611723 |
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NCBI chr11:79,241,927...79,275,173
Ensembl chr11:79,241,938...79,275,188
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G |
Eif2ak3 |
eukaryotic translation initiation factor 2 alpha kinase 3 |
multiple interactions |
ISO |
3-N-1(spermine)-7, 24-dihydroxy-5-cholestane 24-sulfate inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in increased expression of EIF2AK3 mRNA]; [Palmitic Acid co-treated with Oleic Acid] affects the expression of EIF2AK3 mRNA; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of EIF2AK3 mRNA |
CTD |
PMID:30547786 PMID:32369900 |
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NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911
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G |
Elovl5 |
ELOVL fatty acid elongase 5 |
multiple interactions |
ISO |
[GW 4064 co-treated with Oleic Acid] results in decreased expression of ELOVL5 mRNA |
CTD |
PMID:30611723 |
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NCBI chr 8:78,790,846...78,857,307
Ensembl chr 8:78,790,846...78,857,284
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G |
Elovl6 |
ELOVL fatty acid elongase 6 |
multiple interactions |
ISO |
[Farnesol analog co-treated with Oleic Acid] results in increased expression of ELOVL6 mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of ELOVL6 mRNA; [Oleic Acid co-treated with Bezafibrate] results in increased expression of ELOVL6 mRNA; [Oleic Acid co-treated with Fenofibrate] affects the expression of ELOVL6 mRNA; [Oleic Acid co-treated with Rosiglitazone] results in increased expression of ELOVL6 mRNA; [Oleic Acid co-treated with tesaglitazar] results in increased expression of ELOVL6 mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of ELOVL6 mRNA |
CTD |
PMID:24534255 PMID:30547786 PMID:30611723 |
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NCBI chr 2:218,063,682...218,174,767
Ensembl chr 2:218,063,804...218,171,186
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G |
Eno3 |
enolase 3 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of ENO3 mRNA |
CTD |
PMID:30547786 |
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NCBI chr10:55,370,531...55,375,921
Ensembl chr10:55,366,975...55,375,921
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G |
Erlin1 |
ER lipid raft associated 1 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of ERLIN1 mRNA |
CTD |
PMID:30547786 |
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NCBI chr 1:242,921,147...242,956,472
Ensembl chr 1:242,921,152...242,956,394
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G |
Ern1 |
endoplasmic reticulum to nucleus signaling 1 |
multiple interactions |
ISO |
3-N-1(spermine)-7, 24-dihydroxy-5-cholestane 24-sulfate inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in increased expression of ERN1 mRNA]; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of ERN1 mRNA |
CTD |
PMID:32369900 |
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NCBI chr10:91,326,889...91,421,201
Ensembl chr10:91,330,654...91,421,029
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G |
Fabp1 |
fatty acid binding protein 1 |
affects binding multiple interactions decreases expression |
EXP ISO |
Oleic Acid binds to FABP1 protein Oleic acid binds to Fabp1 protein [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of FABP1 mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of FABP1 mRNA; [GW 7647 co-treated with Oleic Acid] results in increased expression of FABP1 mRNA; [Oleic Acid co-treated with Palmitic Acid] results in decreased expression of FABP1 mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of FABP1 mRNA; Dibutyl Phthalate inhibits the reaction [Oleic Acid results in decreased expression of FABP1 mRNA]; Diethylhexyl Phthalate inhibits the reaction [Oleic Acid results in decreased expression of FABP1 mRNA]; Oleic Acid inhibits the reaction [11-(dansylamino)undecanoic acid binds to FABP1 protein] Bezafibrate inhibits the reaction [Oleic Acid binds to FABP1 protein] |
CTD RGD |
PMID:2328261 PMID:30547786 PMID:30611723 PMID:31110286 PMID:38092172 PMID:1939124 More...
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RGD:1626448 |
NCBI chr 4:103,191,015...103,194,791
Ensembl chr 4:103,191,006...103,194,788
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G |
Fabp2 |
fatty acid binding protein 2 |
affects binding |
EXP |
FABP2 protein modified form binds to Oleic Acid |
CTD |
PMID:16137630 |
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NCBI chr 2:211,040,032...211,044,089
Ensembl chr 2:211,040,032...211,044,089
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G |
Fabp4 |
fatty acid binding protein 4 |
multiple interactions affects localization increases expression |
ISO |
[Glucose deficiency co-treated with Clofibrate co-treated with Oleic Acid] results in increased expression of FABP4 mRNA; [Glucose deficiency co-treated with Oleic Acid] results in increased expression of FABP4 mRNA Oleic Acid analog affects the localization of FABP4 protein Oleic Acid results in increased expression of FABP4 mRNA |
CTD |
PMID:8536680 PMID:26739624 PMID:27939595 |
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NCBI chr 2:91,580,879...91,585,567
Ensembl chr 2:91,580,885...91,585,578
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G |
Fas |
Fas cell surface death receptor |
multiple interactions increases expression |
EXP ISO |
[Oleic Acid co-treated with Palmitic Acid] results in increased expression of FAS mRNA; quercetin 3-O-glucuronide inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of FAS mRNA] [Oleic Acid co-treated with Palmitic Acid] results in increased expression of FAS protein; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of FAS mRNA; isosilybin inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of FAS protein] Oleic Acid results in increased expression of FAS mRNA |
CTD |
PMID:26190035 PMID:32918399 PMID:36347319 PMID:36905866 |
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NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
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G |
Fasn |
fatty acid synthase |
multiple interactions |
ISO EXP |
[cyhalothrin co-treated with Oleic Acid] results in increased expression of FASN protein; [Farnesol analog co-treated with Oleic Acid] results in increased expression of FASN mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of FASN mRNA; [GW 7647 co-treated with Oleic Acid] results in increased expression of FASN mRNA; [Oleic Acid co-treated with Bezafibrate] results in increased expression of FASN mRNA; [Oleic Acid co-treated with Dibutyl Phthalate] results in increased expression of FASN protein; [Oleic Acid co-treated with Fenofibrate] affects the expression of FASN mRNA; [Oleic Acid co-treated with Palmitic Acid] results in increased expression of FASN mRNA; Coptidis rhizoma extract inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of FASN mRNA]; GW 6471 inhibits the reaction [[Oleic Acid co-treated with Dibutyl Phthalate] results in increased expression of FASN protein]; Metformin inhibits the reaction [[cyhalothrin co-treated with Oleic Acid] results in increased expression of FASN protein] [Sucrose co-treated with Oleic Acid] results in increased expression of FASN mRNA [Oleic Acid co-treated with Palmitic Acid] inhibits the reaction [Ethanol results in increased expression of FASN mRNA]; [Oleic Acid co-treated with Palmitic Acid] results in decreased expression of FASN mRNA |
CTD |
PMID:24534255 PMID:26854922 PMID:26895660 PMID:30611723 PMID:33508418 PMID:36529352 PMID:38103844 More...
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NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261
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G |
Fdft1 |
farnesyl diphosphate farnesyl transferase 1 |
multiple interactions |
ISO |
[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of FDFT1 mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of FDFT1 mRNA |
CTD |
PMID:30611723 |
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NCBI chr15:37,412,143...37,440,198
Ensembl chr15:37,412,146...37,440,287
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G |
Fdps |
farnesyl diphosphate synthase |
multiple interactions |
ISO |
[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in decreased expression of FDPS mRNA |
CTD |
PMID:30611723 |
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NCBI chr 2:174,497,402...174,507,031
Ensembl chr 2:174,486,665...174,507,776
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G |
Ffar1 |
free fatty acid receptor 1 |
decreases expression |
EXP |
Oleic Acid results in decreased expression of FFAR1 mRNA |
CTD |
PMID:24349266 |
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NCBI chr 1:86,111,368...86,112,272
Ensembl chr 1:86,111,368...86,112,272
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G |
Fgf21 |
fibroblast growth factor 21 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of FGF21 mRNA; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of FGF21 mRNA |
CTD |
PMID:30547786 |
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NCBI chr 1:96,083,360...96,084,911
Ensembl chr 1:96,083,441...96,090,454
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G |
Fis1 |
fission, mitochondrial 1 |
multiple interactions |
ISO |
3-N-1(spermine)-7, 24-dihydroxy-5-cholestane 24-sulfate inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in increased expression of FIS1 mRNA]; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of FIS1 mRNA |
CTD |
PMID:32369900 |
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NCBI chr12:19,708,560...19,723,392
Ensembl chr12:19,708,558...19,723,377
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G |
Flot1 |
flotillin 1 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of FLOT1 mRNA |
CTD |
PMID:30547786 |
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NCBI chr20:2,917,864...2,927,993
Ensembl chr20:2,917,137...2,927,978
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G |
Fnta |
farnesyltransferase, CAAX box, subunit alpha |
multiple interactions |
ISO |
[Farnesol analog co-treated with Oleic Acid] results in increased expression of FNTA mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of FNTA mRNA |
CTD |
PMID:30611723 |
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NCBI chr16:66,065,131...66,083,460
Ensembl chr16:66,065,132...66,083,460
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G |
Fntb |
farnesyltransferase, CAAX box, subunit beta |
multiple interactions |
ISO |
[GW 4064 co-treated with Oleic Acid] results in decreased expression of FNTB mRNA |
CTD |
PMID:30611723 |
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NCBI chr 6:95,536,540...95,619,587
Ensembl chr 6:95,470,683...95,619,586
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G |
Foxa1 |
forkhead box A1 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of FOXA1 mRNA; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of FOXA1 mRNA |
CTD |
PMID:30547786 |
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NCBI chr 6:75,099,907...75,136,534
Ensembl chr 6:75,103,503...75,136,188
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G |
Foxo1 |
forkhead box O1 |
multiple interactions |
ISO |
[Oleic Acid co-treated with Palmitic Acid] results in decreased phosphorylation of FOXO1 protein; FOXO1 protein affects the reaction [[Oleic Acid co-treated with Palmitic Acid] inhibits the reaction [INS1 protein inhibits the reaction [[Cyclic AMP co-treated with Dexamethasone] results in increased expression of G6PC1 protein]]]; FOXO1 protein affects the reaction [[Oleic Acid co-treated with Palmitic Acid] inhibits the reaction [INS1 protein inhibits the reaction [[Cyclic AMP co-treated with Dexamethasone] results in increased expression of PEPCK protein]]]; FOXO1 protein affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of NFE2L2 mRNA]; FOXO1 protein affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of NRF1 mRNA]; FOXO1 protein affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARGC1A mRNA]; FOXO1 protein affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of TFAM mRNA] |
CTD |
PMID:26847930 |
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NCBI chr 2:136,312,168...136,390,603
Ensembl chr 2:136,312,168...136,387,790
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G |
Fth1 |
ferritin heavy chain 1 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of FTH1 protein; ginkgolide B inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of FTH1 protein] |
CTD |
PMID:32976958 |
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NCBI chr 1:206,627,142...206,629,430
Ensembl chr 1:206,627,103...206,725,424
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G |
G6pc1 |
glucose-6-phosphatase catalytic subunit 1 |
multiple interactions |
ISO |
[Oleic Acid co-treated with Palmitic Acid] inhibits the reaction [INS1 protein inhibits the reaction [[Cyclic AMP co-treated with Dexamethasone] results in increased expression of G6PC1 protein]]; FOXO1 protein affects the reaction [[Oleic Acid co-treated with Palmitic Acid] inhibits the reaction [INS1 protein inhibits the reaction [[Cyclic AMP co-treated with Dexamethasone] results in increased expression of G6PC1 protein]]] |
CTD |
PMID:26847930 |
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NCBI chr10:86,307,400...86,318,766
Ensembl chr10:86,257,668...86,333,804
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G |
Gcg |
glucagon |
multiple interactions increases secretion |
ISO |
GNAT3 protein promotes the reaction [Oleic Acid results in increased secretion of GCG protein] |
CTD |
PMID:23341498 |
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NCBI chr 3:47,113,914...47,122,958
Ensembl chr 3:47,113,914...47,122,929
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G |
Gclc |
glutamate-cysteine ligase, catalytic subunit |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of GCLC protein; Escin inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of GCLC protein] |
CTD |
PMID:36905866 |
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NCBI chr 8:78,629,899...78,668,547
Ensembl chr 8:78,630,127...78,668,544
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G |
Gclm |
glutamate cysteine ligase, modifier subunit |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of GCLM protein; Escin inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of GCLM protein] |
CTD |
PMID:36905866 |
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NCBI chr 2:210,347,482...210,367,537
Ensembl chr 2:210,347,482...210,367,535
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G |
Ggps1 |
geranylgeranyl diphosphate synthase 1 |
multiple interactions |
ISO |
[GW 4064 co-treated with Oleic Acid] results in decreased expression of GGPS1 mRNA |
CTD |
PMID:30611723 |
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NCBI chr17:51,263,262...51,282,471
Ensembl chr17:51,263,263...51,276,220
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G |
Ggt1 |
gamma-glutamyltransferase 1 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid] affects the expression of GGT1 mRNA |
CTD |
PMID:30547786 |
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NCBI chr20:13,074,695...13,104,095
Ensembl chr20:13,074,700...13,108,442
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G |
Glp1r |
glucagon-like peptide 1 receptor |
multiple interactions affects localization |
EXP |
[Glucose co-treated with Oleic Acid] results in decreased expression of GLP1R protein; Acetylcysteine inhibits the reaction [Oleic Acid results in increased degradation of and results in decreased expression of GLP1R protein]; Chloroquine inhibits the reaction [Oleic Acid results in increased degradation of and results in decreased expression of GLP1R protein]; exenatide inhibits the reaction [[Glucose co-treated with Oleic Acid] results in decreased expression of GLP1R protein]; Oleic Acid results in increased degradation of and results in decreased expression of GLP1R protein; wortmannin inhibits the reaction [Oleic Acid results in increased degradation of and results in decreased expression of GLP1R protein] Oleic Acid affects the localization of GLP1R protein |
CTD |
PMID:22925809 |
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NCBI chr20:8,972,004...9,010,241
Ensembl chr20:8,972,004...9,010,241
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G |
Glud1 |
glutamate dehydrogenase 1 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of GLUD1 mRNA |
CTD |
PMID:30547786 |
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NCBI chr16:9,640,312...9,673,961
Ensembl chr16:9,640,312...9,673,957
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G |
Gnat3 |
G protein subunit alpha transducin 3 |
multiple interactions |
ISO |
GNAT3 protein promotes the reaction [Oleic Acid results in increased secretion of GCG protein] |
CTD |
PMID:23341498 |
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NCBI chr 4:17,162,500...17,212,283
Ensembl chr 4:17,162,490...17,212,283
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G |
Gpam |
glycerol-3-phosphate acyltransferase, mitochondrial |
multiple interactions |
ISO |
[Oleic Acid co-treated with Dibutyl Phthalate] results in increased expression of GPAM protein; acadesine inhibits the reaction [[Oleic Acid co-treated with Dibutyl Phthalate] results in increased expression of GPAM protein]; GW 6471 inhibits the reaction [[Oleic Acid co-treated with Dibutyl Phthalate] results in increased expression of GPAM protein] |
CTD |
PMID:33508418 |
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NCBI chr 1:254,106,323...254,170,755
Ensembl chr 1:254,106,331...254,142,639
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G |
Gpat3 |
glycerol-3-phosphate acyltransferase 3 |
increases expression multiple interactions |
ISO |
Oleic Acid results in increased expression of GPAT3 mRNA [GW 4064 co-treated with Oleic Acid] results in decreased expression of GPAT3 mRNA; [GW 7647 co-treated with Oleic Acid] results in increased expression of GPAT3 mRNA |
CTD |
PMID:30611723 |
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NCBI chr14:8,715,367...8,768,051
Ensembl chr14:8,714,373...8,766,490
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G |
Gpat4 |
glycerol-3-phosphate acyltransferase 4 |
multiple interactions |
ISO |
[Farnesol analog co-treated with Oleic Acid] results in increased expression of GPAT4 mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of GPAT4 mRNA |
CTD |
PMID:30611723 |
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NCBI chr16:68,819,031...68,852,903
Ensembl chr16:68,819,079...68,852,901
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G |
Gpt |
glutamic--pyruvic transaminase |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid] results in increased activity of GPT protein; ginkgolide B inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in increased activity of GPT protein] |
CTD |
PMID:32976958 |
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NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
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G |
Gpx4 |
glutathione peroxidase 4 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of GPX4 protein; ginkgolide B inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of GPX4 protein]; NFE2L2 protein affects the reaction [[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of GPX4 protein] |
CTD |
PMID:32976958 |
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NCBI chr 7:9,650,186...9,652,982
Ensembl chr 7:9,650,185...9,652,982
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G |
Gsk3b |
glycogen synthase kinase 3 beta |
multiple interactions decreases phosphorylation |
ISO |
6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Oleic Acid results in decreased phosphorylation of GSK3B protein]]; 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [NAD inhibits the reaction [Oleic Acid results in decreased phosphorylation of GSK3B protein]]; [N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride co-treated with NAD] inhibits the reaction [Oleic Acid results in decreased phosphorylation of GSK3B protein]; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Oleic Acid results in decreased phosphorylation of GSK3B protein]; NAD inhibits the reaction [Oleic Acid results in decreased phosphorylation of GSK3B protein]; PARP1 protein affects the reaction [Oleic Acid results in decreased phosphorylation of GSK3B protein] |
CTD |
PMID:25536389 |
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NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
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G |
Gsta1 |
glutathione S-transferase alpha 1 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid] affects the expression of GSTA1 mRNA |
CTD |
PMID:30547786 |
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NCBI chr 9:23,703,476...23,720,121
Ensembl chr 9:23,703,477...23,720,121
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G |
Hadh |
hydroxyacyl-CoA dehydrogenase |
multiple interactions |
ISO |
[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of HADH mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of HADH mRNA |
CTD |
PMID:30611723 |
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NCBI chr 2:219,787,935...219,830,335
Ensembl chr 2:219,787,927...219,830,353
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G |
Hadha |
hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit alpha |
increases expression multiple interactions |
ISO |
Oleic Acid results in increased expression of HADHA mRNA [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of HADHA mRNA; [Farnesol analog co-treated with Oleic Acid] results in increased expression of HADHA mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of HADHA mRNA; [GW 7647 co-treated with Oleic Acid] results in increased expression of HADHA mRNA; GW 7647 promotes the reaction [Oleic Acid results in increased expression of HADHA mRNA] |
CTD |
PMID:30611723 |
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NCBI chr 6:26,187,969...26,227,605
Ensembl chr 6:26,187,956...26,227,869
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G |
Hadhb |
hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta |
multiple interactions increases expression |
ISO |
[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of HADHB mRNA; [Farnesol analog co-treated with Oleic Acid] results in increased expression of HADHB mRNA; [GW 7647 co-treated with Oleic Acid] results in increased expression of HADHB mRNA; GW 7647 promotes the reaction [Oleic Acid results in increased expression of HADHB mRNA]; Oleic Acid promotes the reaction [GW 7647 results in increased expression of HADHB mRNA] |
CTD |
PMID:30611723 |
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NCBI chr 6:26,153,572...26,187,668
Ensembl chr 6:26,153,578...26,184,869
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G |
Havcr1 |
hepatitis A virus cellular receptor 1 |
increases secretion |
ISO |
Oleic Acid results in increased secretion of HAVCR1 protein |
CTD |
PMID:31686351 |
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NCBI chr10:31,118,667...31,151,730
Ensembl chr10:31,119,088...31,151,698
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G |
Hif1a |
hypoxia inducible factor 1 subunit alpha |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of HIF1A protein; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of HIF1A protein |
CTD |
PMID:30547786 |
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NCBI chr 6:92,624,059...92,669,262
Ensembl chr 6:92,624,390...92,669,261
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G |
Hilpda |
hypoxia inducible lipid droplet-associated |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of HILPDA protein; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of HILPDA protein |
CTD |
PMID:30547786 |
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NCBI chr 4:57,871,088...57,874,048
Ensembl chr 4:57,871,110...57,874,557
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G |
Hmgcr |
3-hydroxy-3-methylglutaryl-CoA reductase |
multiple interactions |
ISO |
[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of HMGCR mRNA; [Farnesol analog co-treated with Oleic Acid] results in increased expression of HMGCR mRNA; [GW 7647 co-treated with Oleic Acid] results in increased expression of HMGCR mRNA [[Palmitic Acid co-treated with Oleic Acid] co-treated with IFNA2 protein alternative form] results in decreased expression of HMGCR protein |
CTD |
PMID:30611723 PMID:31299271 |
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NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703
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G |
Hmgcs1 |
3-hydroxy-3-methylglutaryl-CoA synthase 1 |
multiple interactions |
ISO |
[perfluorodecanoic acid co-treated with Oleic Acid] results in increased expression of HMGCS1 mRNA |
CTD |
PMID:36423729 |
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NCBI chr 2:51,649,368...51,667,100
Ensembl chr 2:51,649,497...51,667,100
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G |
Hmox1 |
heme oxygenase 1 |
multiple interactions |
ISO |
[gastrodin co-treated with Oleic Acid] results in increased expression of HMOX1 protein; [Palmitic Acid co-treated with Oleic Acid] results in decreased expression of HMOX1 protein; dorsomorphin inhibits the reaction [[gastrodin co-treated with Oleic Acid] results in increased expression of HMOX1 protein]; Escin inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of HMOX1 protein]; ginkgolide B inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of HMOX1 protein]; NFE2L2 protein affects the reaction [[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of HMOX1 protein] |
CTD |
PMID:26634892 PMID:32976958 PMID:36905866 |
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NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
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G |
Hnf4a |
hepatocyte nuclear factor 4, alpha |
multiple interactions increases expression |
EXP ISO |
sophocarpine inhibits the reaction [Oleic Acid results in increased expression of HNF4A protein] [Palmitic Acid co-treated with Oleic Acid] affects the expression of HNF4A mRNA |
CTD |
PMID:23395669 PMID:30547786 |
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NCBI chr 3:152,186,787...152,248,320
Ensembl chr 3:152,186,787...152,248,320
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G |
Hsdl2 |
hydroxysteroid dehydrogenase like 2 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of HSDL2 mRNA; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of HSDL2 mRNA |
CTD |
PMID:30547786 |
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NCBI chr 5:74,443,933...74,479,104
Ensembl chr 5:74,443,872...74,479,839
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G |
Hspa5 |
heat shock protein family A (Hsp70) member 5 |
increases expression multiple interactions |
EXP ISO |
Oleic Acid results in increased expression of HSPA5 mRNA [Oleic Acid co-treated with Palmitic Acid] results in increased expression of HSPA5 protein; BACE1 protein affects the reaction [SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of HSPA5 protein]]; MIR497 affects the reaction [SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of HSPA5 protein]]; Oleic Acid inhibits the reaction [[Palmitates co-treated with bisphenol A] results in increased expression of HSPA5 mRNA]; SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of HSPA5 protein] [Palmitic Acid co-treated with Oleic Acid] affects the expression of HSPA5 mRNA |
CTD |
PMID:24349266 PMID:30547786 PMID:32976987 PMID:37009739 |
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NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
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G |
Il18 |
interleukin 18 |
multiple interactions |
ISO |
[perfluorodecanoic acid co-treated with Oleic Acid] results in increased expression of IL18 mRNA; [perfluorodecanoic acid co-treated with Oleic Acid] results in increased secretion of IL18 protein |
CTD |
PMID:36423729 |
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NCBI chr 8:50,904,630...50,932,887
Ensembl chr 8:50,906,960...50,932,887
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G |
Il1a |
interleukin 1 alpha |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of IL1A mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of IL1A mRNA |
CTD |
PMID:30547786 |
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NCBI chr 3:116,526,601...116,537,055
Ensembl chr 3:116,526,604...116,536,822
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G |
Il1b |
interleukin 1 beta |
multiple interactions increases expression |
EXP ISO |
[Oleic Acid co-treated with Palmitic Acid] results in increased expression of IL1B protein; Dexamethasone inhibits the reaction [Oleic Acid results in increased expression of IL1B mRNA]; gossypin inhibits the reaction [Oleic Acid results in increased expression of IL1B mRNA]; quercetin 3-O-glucuronide inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of IL1B protein] [Oleic Acid co-treated with Palmitic Acid] results in increased expression of IL1B protein; BACE1 protein affects the reaction [SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of IL1B protein]]; MIR497 affects the reaction [SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of IL1B protein]]; SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of IL1B protein] [Oleic Acid co-treated with Palmitic Acid] results in increased expression of IL1B mRNA; [perfluorodecanoic acid co-treated with Oleic Acid] results in increased expression of IL1B mRNA; [perfluorodecanoic acid co-treated with Oleic Acid] results in increased secretion of IL1B protein; Coptidis rhizoma extract inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of IL1B mRNA] |
CTD |
PMID:26190035 PMID:36423729 PMID:37009739 PMID:37696682 PMID:38103844 |
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NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
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G |
Il6 |
interleukin 6 |
multiple interactions increases expression decreases expression |
EXP ISO |
3'-O-(4-benzoyl)benzoyladenosine 5'-triphosphate promotes the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased secretion of IL6 protein]; [Oleic Acid co-treated with Palmitic Acid] results in increased secretion of IL6 protein; Adenosine Triphosphate promotes the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased secretion of IL6 protein]; coomassie Brilliant Blue inhibits the reaction [3'-O-(4-benzoyl)benzoyladenosine 5'-triphosphate promotes the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased secretion of IL6 protein]]; coomassie Brilliant Blue inhibits the reaction [Adenosine Triphosphate promotes the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased secretion of IL6 protein]]; Dexamethasone inhibits the reaction [Oleic Acid results in increased expression of IL6 mRNA]; gossypin inhibits the reaction [Oleic Acid results in increased expression of IL6 mRNA]; Resveratrol inhibits the reaction [3'-O-(4-benzoyl)benzoyladenosine 5'-triphosphate promotes the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased secretion of IL6 protein]]; Resveratrol inhibits the reaction [Adenosine Triphosphate promotes the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased secretion of IL6 protein]]; SB 203580 inhibits the reaction [3'-O-(4-benzoyl)benzoyladenosine 5'-triphosphate promotes the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased secretion of IL6 protein]]; SB 203580 inhibits the reaction [Adenosine Triphosphate promotes the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased secretion of IL6 protein]] [Oleic Acid co-treated with Palmitic Acid] results in increased expression of IL6 protein; BACE1 protein affects the reaction [SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of IL6 protein]]; MIR497 affects the reaction [SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of IL6 protein]]; SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of IL6 protein] Oleic Acid results in decreased expression of IL6 mRNA Oleic Acid results in increased expression of IL6 mRNA; Oleic Acid results in increased expression of IL6 protein [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in decreased expression of IL6 mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of IL6 mRNA; [GW 7647 co-treated with Oleic Acid] results in decreased expression of IL6 mRNA; [Oleic Acid co-treated with Palmitic Acid] results in increased expression of IL6 mRNA; Coptidis rhizoma extract inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of IL6 mRNA]; dorsomorphin inhibits the reaction [gastrodin inhibits the reaction [Oleic Acid results in increased expression of IL6 mRNA]]; gastrodin inhibits the reaction [Oleic Acid results in increased expression of IL6 mRNA]; Sorafenib inhibits the reaction [Oleic Acid results in increased expression of IL6 protein] |
CTD |
PMID:25348860 PMID:26634892 PMID:30611723 PMID:32918399 PMID:37009739 PMID:37696682 PMID:38103844 More...
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NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
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G |
Ins1 |
insulin 1 |
multiple interactions increases secretion |
ISO EXP |
[Oleic Acid co-treated with Palmitic Acid] inhibits the reaction [INS1 protein inhibits the reaction [[Cyclic AMP co-treated with Dexamethasone] results in increased expression of G6PC1 protein]]; [Oleic Acid co-treated with Palmitic Acid] inhibits the reaction [INS1 protein inhibits the reaction [[Cyclic AMP co-treated with Dexamethasone] results in increased expression of PEPCK protein]]; FOXO1 protein affects the reaction [[Oleic Acid co-treated with Palmitic Acid] inhibits the reaction [INS1 protein inhibits the reaction [[Cyclic AMP co-treated with Dexamethasone] results in increased expression of G6PC1 protein]]]; FOXO1 protein affects the reaction [[Oleic Acid co-treated with Palmitic Acid] inhibits the reaction [INS1 protein inhibits the reaction [[Cyclic AMP co-treated with Dexamethasone] results in increased expression of PEPCK protein]]] Oleic Acid results in increased secretion of INS1 protein Oleic Acid promotes the reaction [Glucose results in increased secretion of INS1 protein] |
CTD |
PMID:24349266 PMID:26847930 |
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NCBI chr 1:251,244,973...251,245,540
Ensembl chr 1:251,244,973...251,245,536
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G |
Ins2 |
insulin 2 |
multiple interactions |
ISO |
[Oleic Acid co-treated with INS protein] results in increased expression of SERPINE1 mRNA; [Oleic Acid co-treated with INS protein] results in increased expression of SERPINE1 protein; Bezafibrate inhibits the reaction [[Oleic Acid co-treated with INS protein] results in increased expression of SERPINE1 mRNA]; Bezafibrate inhibits the reaction [[Oleic Acid co-treated with INS protein] results in increased expression of SERPINE1 protein]; troglitazone promotes the reaction [[Oleic Acid co-treated with INS protein] results in increased expression of SERPINE1 mRNA]; troglitazone promotes the reaction [[Oleic Acid co-treated with INS protein] results in increased expression of SERPINE1 protein] [[Dexamethasone co-treated with INS protein co-treated with 1-Methyl-3-isobutylxanthine] co-treated with alitretinoin] results in increased uptake of Oleic Acid |
CTD |
PMID:10777552 PMID:11292061 |
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NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775
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G |
Insr |
insulin receptor |
decreases phosphorylation multiple interactions |
ISO |
Oleic Acid results in decreased phosphorylation of INSR protein 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Oleic Acid results in decreased phosphorylation of INSR protein]]; 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [NAD inhibits the reaction [Oleic Acid results in decreased phosphorylation of INSR protein]]; [N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride co-treated with NAD] inhibits the reaction [Oleic Acid results in decreased phosphorylation of INSR protein]; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Oleic Acid results in decreased phosphorylation of INSR protein]; NAD inhibits the reaction [Oleic Acid results in decreased phosphorylation of INSR protein]; PARP1 protein affects the reaction [Oleic Acid results in decreased phosphorylation of INSR protein] |
CTD |
PMID:25536389 |
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NCBI chr12:1,193,193...1,330,976
Ensembl chr12:1,197,100...1,330,883
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G |
Irs2 |
insulin receptor substrate 2 |
multiple interactions decreases expression |
EXP ISO |
IRS2 inhibits the reaction [Oleic Acid results in increased cleavage of CASP9 protein]; Oleic Acid inhibits the reaction [IRS2 results in increased phosphorylation of and results in increased activity of AKT1 protein] Oleic Acid results in decreased expression of IRS2 protein Metformin inhibits the reaction [Oleic Acid results in decreased expression of IRS2 protein]; qidan inhibits the reaction [Oleic Acid results in decreased expression of IRS2 protein] |
CTD |
PMID:14604813 PMID:36592823 |
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NCBI chr16:78,488,249...78,512,482
Ensembl chr16:78,485,045...78,512,482
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G |
Iyd |
iodotyrosine deiodinase |
multiple interactions |
ISO |
Oleic Acid inhibits the reaction [IYD protein results in increased metabolism of Monoiodotyrosine] |
CTD |
PMID:33352258 |
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NCBI chr 1:40,003,999...40,019,323
Ensembl chr 1:40,004,041...40,019,319
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G |
Jak1 |
Janus kinase 1 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of JAK1 protein; [Palmitic Acid co-treated with Oleic Acid] affects the expression of JAK1 mRNA; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of JAK1 protein |
CTD |
PMID:30547786 |
|
NCBI chr 5:115,780,248...115,888,841
Ensembl chr 5:115,780,248...115,888,926
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G |
Jak2 |
Janus kinase 2 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid] affects the expression of JAK2 mRNA |
CTD |
PMID:30547786 |
|
NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189
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G |
Keap1 |
Kelch-like ECH-associated protein 1 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid] results in increased expression of KEAP1 protein; Escin inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in increased expression of KEAP1 protein] |
CTD |
PMID:36905866 |
|
NCBI chr 8:19,768,375...19,777,862
Ensembl chr 8:19,768,375...19,777,862
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G |
Lamb1 |
laminin subunit beta 1 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of LAMB1 mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of LAMB1 mRNA |
CTD |
PMID:30547786 |
|
NCBI chr 6:47,835,492...47,902,585
Ensembl chr 6:47,835,525...47,902,585
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G |
Ldlr |
low density lipoprotein receptor |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of LDLR mRNA |
CTD |
PMID:30547786 |
|
NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580
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G |
Lep |
leptin |
decreases expression increases expression multiple interactions |
ISO EXP |
Oleic Acid results in decreased expression of LEP mRNA Oleic Acid results in increased expression of LEP mRNA sophocarpine inhibits the reaction [Oleic Acid results in increased expression of LEP mRNA] |
CTD |
PMID:9002984 PMID:23395669 |
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NCBI chr 4:57,661,127...57,675,262
Ensembl chr 4:57,661,131...57,675,262
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G |
Lipc |
lipase C, hepatic type |
multiple interactions decreases expression |
ISO |
[LIPC gene mutant form co-treated with LIPG gene mutant form] results in decreased abundance of Oleic Acid Oleic Acid results in decreased expression of LIPC mRNA [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of LIPC mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of LIPC mRNA; Sorafenib inhibits the reaction [Oleic Acid results in decreased expression of LIPC mRNA] |
CTD |
PMID:24777581 PMID:30611723 PMID:32918399 |
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NCBI chr 8:71,509,633...71,635,663
Ensembl chr 8:71,509,635...71,635,464
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G |
Lipg |
lipase G, endothelial type |
multiple interactions |
ISO |
[LIPC gene mutant form co-treated with LIPG gene mutant form] results in decreased abundance of Oleic Acid |
CTD |
PMID:24777581 |
|
NCBI chr18:68,514,923...68,536,105
Ensembl chr18:68,514,923...68,536,260
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G |
Lox |
lysyl oxidase |
increases activity |
ISO |
Oleic Acid results in increased activity of LOX protein |
CTD |
PMID:26240151 |
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NCBI chr18:45,964,544...45,977,431
Ensembl chr18:45,967,343...46,041,477
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G |
Lpin1 |
lipin 1 |
multiple interactions |
ISO |
[Farnesol analog co-treated with Oleic Acid] results in increased expression of LPIN1 mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of LPIN1 mRNA |
CTD |
PMID:30611723 |
|
NCBI chr 6:39,309,198...39,417,034
Ensembl chr 6:39,312,748...39,417,097
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G |
Lpin2 |
lipin 2 |
multiple interactions |
ISO |
[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in decreased expression of LPIN2 mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of LPIN2 mRNA |
CTD |
PMID:30611723 |
|
NCBI chr 9:111,083,378...111,158,193
Ensembl chr 9:111,083,745...111,158,193
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G |
Lpin3 |
lipin 3 |
decreases expression multiple interactions |
ISO |
Oleic Acid results in decreased expression of LPIN3 mRNA [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in decreased expression of LPIN3 mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of LPIN3 mRNA |
CTD |
PMID:30611723 |
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NCBI chr 3:149,533,719...149,558,494
Ensembl chr 3:149,534,051...149,558,327
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G |
Map1lc3b |
microtubule-associated protein 1 light chain 3 beta |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid] affects the expression of MAP1LC3B mRNA; [Palmitic Acid co-treated with Oleic Acid] results in increased lipidation of MAP1LC3B protein |
CTD |
PMID:30547786 PMID:36905866 |
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NCBI chr19:49,665,795...49,673,655
Ensembl chr19:49,665,791...49,677,690
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G |
Map3k8 |
mitogen-activated protein kinase kinase kinase 8 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of MAP3K8 mRNA |
CTD |
PMID:30547786 |
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NCBI chr17:53,382,908...53,403,216
Ensembl chr17:53,383,131...53,403,216
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G |
Map4k4 |
mitogen-activated protein kinase kinase kinase kinase 4 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of MAP4K4 mRNA |
CTD |
PMID:30547786 |
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NCBI chr 9:42,200,708...42,326,708
Ensembl chr 9:42,200,278...42,326,698
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G |
Mcat |
malonyl-CoA-acyl carrier protein transacylase |
multiple interactions |
ISO |
[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in decreased expression of MCAT mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of MCAT mRNA |
CTD |
PMID:30611723 |
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NCBI chr 7:114,693,612...114,705,677
Ensembl chr 7:114,693,612...114,704,542
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G |
Mecr |
mitochondrial trans-2-enoyl-CoA reductase |
multiple interactions |
ISO |
[GW 4064 co-treated with Oleic Acid] results in decreased expression of MECR mRNA |
CTD |
PMID:30611723 |
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NCBI chr 5:144,029,684...144,056,373
Ensembl chr 5:144,029,731...144,055,863
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G |
Mff |
mitochondrial fission factor |
multiple interactions |
ISO |
3-N-1(spermine)-7, 24-dihydroxy-5-cholestane 24-sulfate inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in increased expression of MFF mRNA]; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of MFF mRNA |
CTD |
PMID:32369900 |
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NCBI chr 9:84,007,798...84,036,039
Ensembl chr 9:84,007,798...84,036,039
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G |
Mfn1 |
mitofusin 1 |
multiple interactions |
ISO |
3-N-1(spermine)-7, 24-dihydroxy-5-cholestane 24-sulfate inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of MFN1 mRNA]; [Palmitic Acid co-treated with Oleic Acid] results in decreased expression of MFN1 mRNA |
CTD |
PMID:32369900 |
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NCBI chr 2:115,313,380...115,359,651
Ensembl chr 2:115,313,401...115,359,640
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G |
Mgll |
monoglyceride lipase |
multiple interactions |
EXP |
[Oleic Acid co-treated with Palmitic Acid] affects the reaction [Chlorpyrifos results in decreased activity of MGLL protein] |
CTD |
PMID:35151815 |
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NCBI chr 4:121,192,186...121,294,187
Ensembl chr 4:121,192,195...121,294,179
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G |
Mir497 |
microRNA 497 |
multiple interactions |
ISO |
[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of MIR497 mRNA; MIR497 affects the reaction [SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of BACE1 protein]]; MIR497 affects the reaction [SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of DDIT3 protein]]; MIR497 affects the reaction [SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of HSPA5 protein]]; MIR497 affects the reaction [SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of IL1B protein]]; MIR497 affects the reaction [SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of IL6 protein]]; MIR497 affects the reaction [SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of TNF protein]]; SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of MIR497 mRNA] |
CTD |
PMID:37009739 |
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NCBI chr10:54,951,514...54,951,582
Ensembl chr10:54,951,505...54,951,584
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G |
Mlkl |
mixed lineage kinase domain like pseudokinase |
multiple interactions increases phosphorylation |
ISO |
necrostatin-1 inhibits the reaction [Oleic Acid results in increased phosphorylation of MLKL protein]; PGAM5 protein promotes the reaction [Oleic Acid results in increased phosphorylation of MLKL protein] |
CTD |
PMID:36273635 |
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NCBI chr19:39,277,526...39,304,555
Ensembl chr19:39,276,785...39,304,502
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G |
Mlxipl |
MLX interacting protein-like |
multiple interactions |
ISO |
[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in decreased expression of MLXIPL mRNA; [Farnesol analog co-treated with Oleic Acid] results in decreased expression of MLXIPL mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of MLXIPL mRNA; [GW 7647 co-treated with Oleic Acid] results in decreased expression of MLXIPL mRNA |
CTD |
PMID:30611723 |
|
NCBI chr12:21,541,608...21,577,120
Ensembl chr12:21,543,576...21,577,112
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G |
Mmp2 |
matrix metallopeptidase 2 |
multiple interactions |
ISO |
[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of MMP2 mRNA |
CTD |
PMID:26187275 |
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NCBI chr19:14,154,657...14,182,870
Ensembl chr19:14,154,657...14,182,870
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G |
Mmp9 |
matrix metallopeptidase 9 |
multiple interactions |
ISO |
[Oleic Acid co-treated with Palmitic Acid] results in increased expression of MMP9 protein; Coptidis rhizoma extract inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of MMP9 protein] |
CTD |
PMID:38103844 |
|
NCBI chr 3:153,684,158...153,692,118
Ensembl chr 3:153,683,858...153,692,120
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G |
Mt1 |
metallothionein 1 |
multiple interactions |
EXP |
[Oleic Acid co-treated with Palmitic Acid] inhibits the reaction [Ethanol results in increased expression of MT1 mRNA]; [Oleic Acid co-treated with Palmitic Acid] results in increased expression of MT1 mRNA; Ethanol inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of MT1 mRNA] |
CTD |
PMID:26854922 |
|
NCBI chr19:10,826,032...10,827,048
Ensembl chr19:10,826,032...10,827,049 Ensembl chr17:10,826,032...10,827,049
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G |
Mt2A |
metallothionein 2A |
multiple interactions |
EXP |
[Oleic Acid co-treated with Palmitic Acid] results in increased expression of MT2A mRNA |
CTD |
PMID:26854922 |
|
NCBI chr19:10,832,009...10,832,783
Ensembl chr19:10,832,002...10,832,784
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G |
Mttp |
microsomal triglyceride transfer protein |
multiple interactions decreases expression |
ISO |
[GW 4064 co-treated with Oleic Acid] results in decreased expression of MTTP mRNA; [GW 7647 co-treated with Oleic Acid] results in decreased expression of MTTP mRNA; [Oleic Acid co-treated with Palmitic Acid] results in decreased expression of MTTP mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of MTTP mRNA; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of MTTP mRNA; isosilybin inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of MTTP mRNA]; Sorafenib inhibits the reaction [Oleic Acid results in decreased expression of MTTP mRNA] |
CTD |
PMID:30547786 PMID:30611723 PMID:32918399 PMID:36347319 PMID:38092172 |
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NCBI chr 2:226,613,090...226,654,239
Ensembl chr 2:226,613,090...226,654,239
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G |
Nfe2l2 |
NFE2 like bZIP transcription factor 2 |
multiple interactions increases expression |
ISO |
[gastrodin co-treated with Oleic Acid] results in increased phosphorylation of and affects the localization of NFE2L2 protein; [Palmitic Acid co-treated with Oleic Acid] results in decreased expression of and affects the localization of NFE2L2 protein; [Palmitic Acid co-treated with Oleic Acid] results in decreased expression of NFE2L2 protein; dorsomorphin inhibits the reaction [[gastrodin co-treated with Oleic Acid] results in increased phosphorylation of and affects the localization of NFE2L2 protein]; Escin inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of NFE2L2 protein]; ginkgolide B inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of and affects the localization of NFE2L2 protein]; NFE2L2 protein affects the reaction [[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of GPX4 protein]; NFE2L2 protein affects the reaction [[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of HMOX1 protein] [Oleic Acid co-treated with Palmitic Acid] results in decreased expression of NFE2L2 mRNA; FOXO1 protein affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of NFE2L2 mRNA] Oleic Acid results in increased expression of NFE2L2 mRNA; Oleic Acid results in increased expression of NFE2L2 protein |
CTD |
PMID:26634892 PMID:26847930 PMID:28555106 PMID:32976958 PMID:36905866 |
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NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
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G |
Nos3 |
nitric oxide synthase 3 |
decreases expression |
ISO |
Oleic Acid results in decreased expression of NOS3 mRNA |
CTD |
PMID:16895544 |
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NCBI chr 4:10,793,834...10,814,170
Ensembl chr 4:10,793,834...10,814,166
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G |
Nqo1 |
NAD(P)H quinone dehydrogenase 1 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of NQO1 protein; Escin inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of NQO1 protein] |
CTD |
PMID:36905866 |
|
NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
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G |
Nr0b2 |
nuclear receptor subfamily 0, group B, member 2 |
decreases expression increases expression multiple interactions |
ISO EXP |
Oleic Acid results in decreased expression of NR0B2 mRNA Oleic Acid results in increased expression of NR0B2 mRNA [Farnesol analog co-treated with Oleic Acid] results in decreased expression of NR0B2 mRNA; [GW 4064 co-treated with Oleic Acid] results in increased expression of NR0B2 mRNA; [GW 7647 co-treated with Oleic Acid] results in decreased expression of NR0B2 mRNA |
CTD |
PMID:30611723 PMID:32738331 |
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NCBI chr 5:145,779,294...145,782,609
Ensembl chr 5:145,779,294...145,782,609
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G |
Nr1h3 |
nuclear receptor subfamily 1, group H, member 3 |
multiple interactions |
ISO EXP |
[Oleic Acid co-treated with Fenofibrate] affects the expression of NR1H3 mRNA; [Oleic Acid co-treated with muraglitazar] results in increased expression of NR1H3 mRNA; [Oleic Acid co-treated with Rosiglitazone] results in increased expression of NR1H3 mRNA; [Oleic Acid co-treated with tesaglitazar] affects the expression of NR1H3 mRNA; [Oleic Acid co-treated with Troglitazone] affects the expression of NR1H3 mRNA [Oleic Acid co-treated with Palmitic Acid] results in increased expression of NR1H3 mRNA |
CTD |
PMID:24534255 PMID:26190035 |
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NCBI chr 3:77,158,808...77,168,907
Ensembl chr 3:77,158,808...77,168,722
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G |
Nr1h4 |
nuclear receptor subfamily 1, group H, member 4 |
multiple interactions decreases expression |
ISO |
[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in decreased expression of NR1H4 mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of NR1H4 mRNA; [Oleic Acid co-treated with Bezafibrate] results in increased expression of NR1H4 mRNA; [Oleic Acid co-treated with Fenofibrate] results in decreased expression of NR1H4 mRNA; [Oleic Acid co-treated with muraglitazar] results in increased expression of NR1H4 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of NR1H4 mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of NR1H4 mRNA Oleic Acid results in decreased expression of NR1H4 mRNA |
CTD |
PMID:24534255 PMID:30547786 PMID:30611723 |
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NCBI chr 7:23,846,122...23,942,085
Ensembl chr 7:23,846,122...23,942,047
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G |
Nr1i3 |
nuclear receptor subfamily 1, group I, member 3 |
multiple interactions |
ISO |
[GW 4064 co-treated with Oleic Acid] results in decreased expression of NR1I3 mRNA; [GW 7647 co-treated with Oleic Acid] results in decreased expression of NR1I3 mRNA; [Oleic Acid co-treated with Fenofibrate] results in increased expression of NR1I3 mRNA; [Oleic Acid co-treated with muraglitazar] results in increased expression of NR1I3 mRNA; [Oleic Acid co-treated with Rosiglitazone] results in decreased expression of NR1I3 mRNA; [Oleic Acid co-treated with Troglitazone] affects the expression of NR1I3 mRNA |
CTD |
PMID:24534255 PMID:30611723 |
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NCBI chr13:83,632,940...83,638,193
Ensembl chr13:83,632,899...83,637,906
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G |
Nrf1 |
nuclear respiratory factor 1 |
multiple interactions |
ISO |
[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of NRF1 mRNA; FOXO1 protein affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of NRF1 mRNA] |
CTD |
PMID:26847930 |
|
NCBI chr 4:58,664,932...58,772,328
Ensembl chr 4:58,664,957...58,825,328
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G |
P2rx7 |
purinergic receptor P2X 7 |
multiple interactions |
EXP |
[Oleic Acid co-treated with Palmitic Acid] results in increased expression of P2RX7 mRNA; [Oleic Acid co-treated with Palmitic Acid] results in increased expression of P2RX7 protein; Resveratrol inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of P2RX7 mRNA]; Resveratrol inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of P2RX7 protein] |
CTD |
PMID:25348860 |
|
NCBI chr12:33,889,709...33,934,168
Ensembl chr12:33,879,745...33,934,619
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G |
Parp1 |
poly (ADP-ribose) polymerase 1 |
increases cleavage increases activity multiple interactions |
ISO |
Oleic Acid results in increased cleavage of PARP1 protein Oleic Acid results in increased activity of PARP1 protein [NAD co-treated with Oleic Acid] results in increased activity of PARP1 protein; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [[NAD co-treated with Oleic Acid] results in increased activity of PARP1 protein]; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Oleic Acid results in increased activity of PARP1 protein]; PARP1 protein affects the reaction [Oleic Acid results in decreased phosphorylation of AKT1 protein]; PARP1 protein affects the reaction [Oleic Acid results in decreased phosphorylation of GSK3B protein]; PARP1 protein affects the reaction [Oleic Acid results in decreased phosphorylation of INSR protein] |
CTD |
PMID:21132278 PMID:25536389 PMID:30165350 |
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NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
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G |
Pc |
pyruvate carboxylase |
decreases expression |
EXP |
Oleic Acid results in decreased expression of PC mRNA |
CTD |
PMID:24349266 |
|
NCBI chr 1:201,799,374...201,898,412
Ensembl chr 1:201,804,267...201,898,380
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G |
Pck1 |
phosphoenolpyruvate carboxykinase 1 |
multiple interactions increases expression |
ISO |
[Glucose deficiency co-treated with Clofibrate co-treated with Oleic Acid] results in increased expression of PCK1 mRNA; [Glucose deficiency co-treated with Oleic Acid] results in increased expression of PCK1 mRNA; [Oleic Acid co-treated with Palmitic Acid] inhibits the reaction [INS1 protein inhibits the reaction [[Cyclic AMP co-treated with Dexamethasone] results in increased expression of PEPCK protein]]; Dexamethasone inhibits the reaction [Oleic Acid results in increased expression of PCK1 mRNA]; FOXO1 protein affects the reaction [[Oleic Acid co-treated with Palmitic Acid] inhibits the reaction [INS1 protein inhibits the reaction [[Cyclic AMP co-treated with Dexamethasone] results in increased expression of PEPCK protein]]] [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of PCK1 mRNA; [Farnesol analog co-treated with Oleic Acid] results in increased expression of PCK1 mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of PCK1 mRNA; [GW 7647 co-treated with Oleic Acid] results in increased expression of PCK1 mRNA |
CTD |
PMID:8536680 PMID:9518257 PMID:26847930 PMID:30611723 |
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NCBI chr 3:161,930,256...161,936,205
Ensembl chr 3:161,930,256...161,936,191
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G |
Pdgfb |
platelet derived growth factor subunit B |
multiple interactions increases expression |
ISO |
Sorafenib inhibits the reaction [Oleic Acid results in increased expression of PDGFB mRNA] |
CTD |
PMID:32918399 |
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NCBI chr 7:111,539,444...111,557,984
Ensembl chr 7:111,540,345...111,557,984
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G |
Pdk4 |
pyruvate dehydrogenase kinase 4 |
increases expression multiple interactions |
ISO |
Oleic Acid results in increased expression of PDK4 mRNA [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of PDK4 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of PDK4 protein; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of PDK4 mRNA; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of PDK4 protein |
CTD |
PMID:26739624 PMID:30547786 |
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NCBI chr 4:33,591,796...33,601,798
Ensembl chr 4:33,589,799...33,601,850
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G |
Pdss1 |
decaprenyl diphosphate synthase subunit 1 |
multiple interactions |
ISO |
[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of PDSS1 mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of PDSS1 mRNA |
CTD |
PMID:30611723 |
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NCBI chr17:85,059,953...85,098,739
Ensembl chr17:85,060,106...85,098,730
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G |
Pebp1 |
phosphatidylethanolamine binding protein 1 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of PEBP1 mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of PEBP1 mRNA |
CTD |
PMID:30547786 |
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NCBI chr12:39,302,864...39,307,064
Ensembl chr12:39,302,840...39,307,862
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G |
Pecr |
peroxisomal trans-2-enoyl-CoA reductase |
decreases expression multiple interactions |
ISO |
Oleic Acid results in decreased expression of PECR mRNA [GW 4064 co-treated with Oleic Acid] results in decreased expression of PECR mRNA; [GW 7647 co-treated with Oleic Acid] results in decreased expression of PECR mRNA |
CTD |
PMID:30611723 |
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NCBI chr 9:73,897,877...73,926,511
Ensembl chr 9:73,897,880...73,926,511
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G |
Pgam5 |
PGAM family member 5, mitochondrial serine/threonine protein phosphatase |
multiple interactions |
ISO |
PGAM5 protein promotes the reaction [Oleic Acid results in increased expression of SQSTM1 protein]; PGAM5 protein promotes the reaction [Oleic Acid results in increased phosphorylation of MLKL protein]; PGAM5 protein promotes the reaction [Oleic Acid results in increased phosphorylation of RIPK1 protein]; PGAM5 protein promotes the reaction [Oleic Acid results in increased phosphorylation of RIPK3 protein] |
CTD |
PMID:36273635 |
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NCBI chr12:46,409,324...46,416,410
Ensembl chr12:46,409,369...46,416,420
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G |
Pik3c2a |
phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid] affects the expression of PIK3C2A mRNA |
CTD |
PMID:30547786 |
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NCBI chr 1:170,577,942...170,684,353
Ensembl chr 1:170,577,942...170,683,472
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G |
Pink1 |
PTEN induced kinase 1 |
multiple interactions decreases expression |
ISO |
3-N-1(spermine)-7, 24-dihydroxy-5-cholestane 24-sulfate inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of PINK1 mRNA]; [Palmitic Acid co-treated with Oleic Acid] results in decreased expression of PINK1 mRNA; Metformin inhibits the reaction [Oleic Acid results in decreased expression of PINK1 protein]; qidan inhibits the reaction [Oleic Acid results in decreased expression of PINK1 protein] |
CTD |
PMID:32369900 PMID:36592823 |
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NCBI chr 5:150,530,523...150,542,635
Ensembl chr 5:150,530,523...150,542,635
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G |
Pklr |
pyruvate kinase L/R |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of PKLR mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of PKLR mRNA |
CTD |
PMID:30547786 |
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NCBI chr 2:174,543,008...174,551,863
Ensembl chr 2:174,543,039...174,551,870
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G |
Pld1 |
phospholipase D1 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of PLD1 mRNA |
CTD |
PMID:30547786 |
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NCBI chr 2:110,849,205...111,047,304
Ensembl chr 2:110,893,608...111,047,692
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G |
Plek |
pleckstrin |
multiple interactions |
ISO |
Oleic Acid promotes the reaction [Guanosine 5'-O-(3-Thiotriphosphate) results in increased phosphorylation of PLEK protein] |
CTD |
PMID:8928743 |
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NCBI chr14:91,397,015...91,429,693
Ensembl chr14:91,397,019...91,454,131
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G |
Plin1 |
perilipin 1 |
increases expression |
ISO |
Oleic Acid results in increased expression of PLIN1 mRNA |
CTD |
PMID:26739624 |
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NCBI chr 1:133,664,294...133,676,854
Ensembl chr 1:133,664,892...133,676,828
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G |
Plin2 |
perilipin 2 |
multiple interactions increases expression |
EXP ISO |
[Oleic Acid co-treated with Palmitic Acid] results in increased expression of PLIN2 mRNA; Oleic Acid promotes the reaction [LG 100268 results in increased expression of PLIN2 protein]; Oleic Acid promotes the reaction [pirinixic acid results in increased expression of PLIN2 protein] Rimonabant inhibits the reaction [Oleic Acid results in increased expression of PLIN2 protein] Oleic Acid results in increased expression of PLIN2 mRNA; Oleic Acid results in increased expression of PLIN2 protein [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of PLIN2 mRNA; [Farnesol analog co-treated with Oleic Acid] results in increased expression of PLIN2 mRNA; [GW 7647 co-treated with Oleic Acid] results in increased expression of PLIN2 mRNA; [Oleic Acid co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of PLIN2 mRNA; [Oleic Acid co-treated with Dichlorodiphenyl Dichloroethylene] results in increased expression of PLIN2 protein; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of PLIN2 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of PLIN2 protein; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of PLIN2 mRNA; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of PLIN2 protein; Bezafibrate promotes the reaction [Oleic Acid results in increased expression of PLIN2 mRNA]; Dichlorodiphenyl Dichloroethylene promotes the reaction [Oleic Acid results in increased expression of PLIN2 protein]; Diethylhexyl Phthalate promotes the reaction [Oleic Acid results in increased expression of PLIN2 protein]; Fenofibrate promotes the reaction [Oleic Acid results in increased expression of PLIN2 mRNA]; muraglitazar promotes the reaction [Oleic Acid results in increased expression of PLIN2 mRNA]; Rosiglitazone promotes the reaction [Oleic Acid results in increased expression of PLIN2 mRNA]; tesaglitazar promotes the reaction [Oleic Acid results in increased expression of PLIN2 mRNA]; Troglitazone promotes the reaction [Oleic Acid results in increased expression of PLIN2 mRNA] |
CTD |
PMID:16489205 PMID:24534255 PMID:25048947 PMID:26739624 PMID:30547786 PMID:30611723 PMID:31570772 PMID:38092172 More...
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NCBI chr 5:101,156,648...101,211,738
Ensembl chr 5:101,154,411...101,242,319
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G |
Plin3 |
perilipin 3 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid] results in increased expression of PLIN3 mRNA |
CTD |
PMID:30547786 |
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NCBI chr 9:1,111,178...1,123,057
Ensembl chr 9:1,102,366...1,123,147
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G |
Plin4 |
perilipin 4 |
multiple interactions increases expression |
ISO |
Bezafibrate promotes the reaction [Oleic Acid results in increased expression of PLIN4 mRNA]; muraglitazar promotes the reaction [Oleic Acid results in increased expression of PLIN4 mRNA]; rosiglitazone promotes the reaction [Oleic Acid results in increased expression of PLIN4 mRNA]; tesaglitazar promotes the reaction [Oleic Acid results in increased expression of PLIN4 mRNA]; troglitazone promotes the reaction [Oleic Acid results in increased expression of PLIN4 mRNA] |
CTD |
PMID:24534255 |
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NCBI chr 9:929,168...938,062
Ensembl chr 9:929,176...938,056
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G |
Plin5 |
perilipin 5 |
multiple interactions |
EXP |
[Oleic Acid co-treated with Palmitic Acid] results in increased expression of PLIN5 mRNA; tetrabromobisphenol A promotes the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of PLIN5 mRNA] |
CTD |
PMID:25048947 |
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NCBI chr 9:939,745...946,188
Ensembl chr 9:939,747...946,120
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G |
Plpp6 |
phospholipid phosphatase 6 |
multiple interactions |
ISO |
[GW 4064 co-treated with Oleic Acid] results in decreased expression of PLPP6 mRNA; [GW 7647 co-treated with Oleic Acid] results in decreased expression of PLPP6 mRNA |
CTD |
PMID:30611723 |
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NCBI chr 1:226,679,100...226,681,952
Ensembl chr 1:226,679,100...226,681,949
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G |
Pnpla3 |
patatin-like phospholipase domain containing 3 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of PNPLA3 mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of PNPLA3 mRNA |
CTD |
PMID:30547786 |
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NCBI chr 7:115,293,538...115,314,077
Ensembl chr 7:115,293,538...115,314,077
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G |
Pon1 |
paraoxonase 1 |
multiple interactions decreases activity |
ISO |
[Calcium co-treated with Oleic Acid] results in increased stability of PON1 protein; Calcium promotes the reaction [Oleic Acid inhibits the reaction [4-hydroxymercuribenzoate results in decreased activity of PON1 protein]]; Oleic Acid inhibits the reaction [4-hydroxymercuribenzoate results in decreased activity of PON1 protein]; Oleic Acid inhibits the reaction [[Ascorbic Acid co-treated with Copper Sulfate] results in decreased activity of PON1 protein]; Oleic Acid inhibits the reaction [Copper promotes the reaction [Ascorbic Acid results in decreased activity of PON1 protein]]; Oleic Acid inhibits the reaction [Hydrogen Peroxide results in decreased activity of PON1 protein]; Oleic Acid inhibits the reaction [PON1 protein results in increased hydrolysis of Paraoxon] Oleic Acid results in decreased activity of PON1 protein |
CTD |
PMID:12871208 PMID:15104111 PMID:15375178 |
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NCBI chr 4:33,294,737...33,325,759
Ensembl chr 4:33,294,722...33,321,360
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G |
Ppara |
peroxisome proliferator activated receptor alpha |
multiple interactions affects binding increases expression affects abundance decreases expression increases activity |
ISO EXP |
Diethylhexyl Phthalate inhibits the reaction [PPARA protein affects the abundance of Oleic Acid]; Oleic Acid binds to and results in increased activity of PPARA protein; Oleic Acid inhibits the reaction [troglitazone results in decreased expression of PPARA mRNA]; PPARA protein promotes the reaction [Oleic Acid results in decreased expression of SLC13A1 mRNA]; PPARA protein promotes the reaction [Oleic Acid results in decreased expression of SLC16A9 mRNA]; PPARA protein promotes the reaction [Oleic Acid results in increased expression of ABCD3 mRNA]; PPARA protein promotes the reaction [Oleic Acid results in increased expression of CYP2C65 mRNA]; PPARA protein promotes the reaction [Oleic Acid results in increased expression of CYP4F16 mRNA]; PPARA protein promotes the reaction [Oleic Acid results in increased expression of SLC27A4 mRNA]; PPARA protein promotes the reaction [Oleic Acid results in increased expression of SLC6A3 mRNA] Oleic Acid binds to PPARA protein Oleic Acid results in increased expression of PPARA mRNA; Oleic Acid results in increased expression of PPARA protein [Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARA mRNA; [Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARA protein; [Oleic Acid co-treated with Palmitic Acid] results in increased expression of PPARA mRNA; [tetrabromobisphenol A co-treated with Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARA mRNA; [Triiodothyronine co-treated with Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARA mRNA; Bezafibrate inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARA mRNA]; Bezafibrate inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARA protein]; Oleic Acid binds to and results in increased activity of PPARA protein; quercetin 3-O-glucuronide inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARA mRNA]; quercetin 3-O-glucuronide inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARA protein] Oleic Acid results in decreased expression of PPAR mRNA; Oleic Acid results in decreased expression of PPARA mRNA; Oleic Acid results in decreased expression of PPARA protein [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in decreased expression of PPARA mRNA; [Farnesol analog co-treated with Oleic Acid] results in increased expression of PPARA mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of PPARA mRNA; [Oleic Acid co-treated with Dibutyl Phthalate] results in increased expression of PPARA protein; [Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARA mRNA; [Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARA protein; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of PPARA mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of PPARA mRNA; [Vehicle Emissions results in increased abundance of Particulate Matter] inhibits the reaction [Oleic Acid results in increased expression of PPARA mRNA]; Benzo(a)pyrene inhibits the reaction [Estradiol inhibits the reaction [Oleic Acid results in decreased expression of PPARA mRNA]]; Benzo(a)pyrene inhibits the reaction [Estradiol inhibits the reaction [Oleic Acid results in decreased expression of PPARA protein]]; Coptidis rhizoma extract inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARA mRNA]; Diethylhexyl Phthalate promotes the reaction [Oleic Acid results in increased activity of and results in increased localization of PPARA protein]; Diethylhexyl Phthalate promotes the reaction [Oleic Acid results in increased expression of PPARA protein]; Estradiol inhibits the reaction [Oleic Acid results in decreased expression of PPARA mRNA]; Estradiol inhibits the reaction [Oleic Acid results in decreased expression of PPARA protein]; GW 6471 inhibits the reaction [[Oleic Acid co-treated with Dibutyl Phthalate] results in increased expression of PPARA protein]; isosilybin inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARA mRNA]; isosilybin inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARA protein]; Oleic Acid binds to and results in increased activity of PPARA protein; Oleic Acid results in increased activity of and results in increased localization of PPARA protein; Plant Extracts inhibits the reaction [Oleic Acid results in decreased expression of PPARA mRNA]; Plant Extracts inhibits the reaction [Oleic Acid results in decreased expression of PPARA protein] Oleic Acid results in increased activity of PPARA protein |
CTD |
PMID:9688458 PMID:10403814 PMID:11056218 PMID:15491415 PMID:15949695 PMID:16731579 PMID:18154422 PMID:18489776 PMID:23603006 PMID:23619606 PMID:25048947 PMID:26190035 PMID:26854922 PMID:27996362 PMID:30547786 PMID:30611723 PMID:31340670 PMID:31730885 PMID:33508418 PMID:35752307 PMID:36347319 PMID:38103844 More...
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NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
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G |
Ppard |
peroxisome proliferator-activated receptor delta |
increases expression multiple interactions decreases expression |
ISO EXP |
Oleic Acid results in increased expression of PPARD mRNA Oleic Acid binds to and results in increased activity of PPARB protein [Oleic Acid co-treated with Palmitic Acid co-treated with Ethanol] results in increased expression of PPARD mRNA; [Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARB mRNA; [Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARD mRNA; Bezafibrate inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARB mRNA]; Oleic Acid binds to and results in increased activity of PPARB protein; tetrabromobisphenol A inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARD mRNA] Oleic Acid results in decreased expression of PPARD mRNA [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of PPARD mRNA; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of PPARD mRNA; Oleic Acid binds to and results in increased activity of PPARB protein |
CTD |
PMID:11172467 PMID:16731579 PMID:24349266 PMID:25048947 PMID:26190035 PMID:26854922 PMID:30547786 More...
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NCBI chr20:6,298,785...6,363,970
Ensembl chr20:6,298,785...6,363,968
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G |
Pparg |
peroxisome proliferator-activated receptor gamma |
increases expression affects binding multiple interactions |
ISO EXP |
Oleic Acid results in increased expression of PPARG mRNA Oleic Acid binds to PPARG protein [Oleic Acid co-treated with Palmitic Acid] inhibits the reaction [Ethanol results in increased expression of PPARG mRNA]; [Oleic Acid co-treated with Palmitic Acid] results in increased expression of PPARG mRNA; Ethanol inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of PPARG mRNA]; tetrabromobisphenol A inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of PPARG mRNA]; Triiodothyronine inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of PPARG mRNA] [cyhalothrin co-treated with Oleic Acid] results in increased expression of PPARG protein; [Farnesol analog co-treated with Oleic Acid] results in increased expression of PPARG mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of PPARG mRNA; [Oleic Acid co-treated with Fenofibrate] results in increased expression of PPARG mRNA; [Oleic Acid co-treated with Palmitic Acid] results in increased expression of PPARG mRNA; [Oleic Acid co-treated with Palmitic Acid] results in increased expression of PPARG protein; [Palmitic Acid co-treated with Oleic Acid] results in decreased expression of PPARG protein; Coptidis rhizoma extract inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of PPARG mRNA]; Coptidis rhizoma extract inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of PPARG protein]; Escin inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in decreased expression of PPARG protein]; Metformin inhibits the reaction [[cyhalothrin co-treated with Oleic Acid] results in increased expression of PPARG protein]; Oleic Acid binds to and results in increased activity of PPARG protein Oleic Acid results in increased expression of PPARG mRNA; Oleic Acid results in increased expression of PPARG protein |
CTD |
PMID:11172467 PMID:18154422 PMID:24534255 PMID:24998974 PMID:25048947 PMID:26190035 PMID:26854922 PMID:27131391 PMID:30611723 PMID:35752307 PMID:36529352 PMID:36905866 PMID:38103844 More...
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NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
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G |
Ppargc1a |
PPARG coactivator 1 alpha |
multiple interactions |
ISO |
[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARGC1A mRNA; FOXO1 protein affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of PPARGC1A mRNA] |
CTD |
PMID:26847930 |
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NCBI chr14:58,860,752...59,516,525
Ensembl chr14:58,861,144...59,512,656
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G |
Prkaa1 |
protein kinase AMP-activated catalytic subunit alpha 1 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of PRKAA1 mRNA |
CTD |
PMID:30547786 |
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NCBI chr 2:54,240,298...54,275,978
Ensembl chr 2:54,240,137...54,275,978
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G |
Prkaa2 |
protein kinase AMP-activated catalytic subunit alpha 2 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid] affects the expression of PRKAA2 mRNA |
CTD |
PMID:30547786 |
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NCBI chr 5:119,807,992...119,879,987
Ensembl chr 5:119,813,226...119,879,543
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G |
Prkn |
parkin RBR E3 ubiquitin protein ligase |
decreases expression multiple interactions |
ISO |
Oleic Acid results in decreased expression of PRKN protein Metformin inhibits the reaction [Oleic Acid results in decreased expression of PRKN protein]; qidan inhibits the reaction [Oleic Acid results in decreased expression of PRKN protein] |
CTD |
PMID:36592823 |
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NCBI chr 1:48,688,651...49,882,520
Ensembl chr 1:48,690,556...49,882,555
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G |
Ptgs2 |
prostaglandin-endoperoxide synthase 2 |
multiple interactions increases expression |
ISO |
dorsomorphin inhibits the reaction [gastrodin inhibits the reaction [Oleic Acid results in increased expression of PTGS2 mRNA]]; gastrodin inhibits the reaction [Oleic Acid results in increased expression of PTGS2 mRNA] |
CTD |
PMID:26634892 |
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NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
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G |
Rab18 |
RAB18, member RAS oncogene family |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of RAB18 mRNA |
CTD |
PMID:30547786 |
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NCBI chr17:54,944,099...54,976,093
Ensembl chr17:54,943,955...54,976,043
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G |
Rabggta |
Rab geranylgeranyltransferase subunit alpha |
multiple interactions |
ISO |
[Farnesol analog co-treated with Oleic Acid] results in decreased expression of RABGGTA mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of RABGGTA mRNA |
CTD |
PMID:30611723 |
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NCBI chr15:29,206,328...29,213,398
Ensembl chr15:29,206,157...29,213,348
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G |
Rabggtb |
Rab geranylgeranyltransferase subunit beta |
multiple interactions |
ISO |
[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of RABGGTB mRNA; [Farnesol analog co-treated with Oleic Acid] results in decreased expression of RABGGTB mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of RABGGTB mRNA |
CTD |
PMID:30611723 |
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NCBI chr 2:242,844,758...242,850,951
Ensembl chr 2:242,844,762...242,851,050
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G |
Rb1 |
RB transcriptional corepressor 1 |
decreases phosphorylation |
ISO |
Oleic Acid results in decreased phosphorylation of RB1 protein |
CTD |
PMID:16027227 |
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NCBI chr15:48,371,295...48,502,473
Ensembl chr15:48,371,296...48,502,302
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G |
Rheb |
Ras homolog, mTORC1 binding |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of RHEB mRNA |
CTD |
PMID:30547786 |
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NCBI chr 4:10,278,970...10,320,160
Ensembl chr 4:10,279,370...10,320,160
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G |
Rhob |
ras homolog family member B |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of RHOB mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of RHOB mRNA |
CTD |
PMID:30547786 |
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NCBI chr 6:31,363,752...31,365,926
Ensembl chr 6:31,363,548...31,366,108
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G |
Ripk1 |
receptor interacting serine/threonine kinase 1 |
multiple interactions increases phosphorylation |
ISO |
necrostatin-1 inhibits the reaction [Oleic Acid results in increased phosphorylation of RIPK1 protein]; PGAM5 protein promotes the reaction [Oleic Acid results in increased phosphorylation of RIPK1 protein] |
CTD |
PMID:36273635 |
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NCBI chr17:30,839,639...30,871,824
Ensembl chr17:30,839,650...30,871,824
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G |
Ripk3 |
receptor-interacting serine-threonine kinase 3 |
increases phosphorylation multiple interactions |
ISO |
Oleic Acid results in increased phosphorylation of RIPK3 protein necrostatin-1 inhibits the reaction [Oleic Acid results in increased phosphorylation of RIPK3 protein]; PGAM5 protein promotes the reaction [Oleic Acid results in increased phosphorylation of RIPK3 protein] |
CTD |
PMID:36273635 |
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NCBI chr15:29,283,153...29,292,107
Ensembl chr15:29,283,145...29,292,121
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G |
Rock2 |
Rho-associated coiled-coil containing protein kinase 2 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of ROCK2 protein; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of ROCK2 protein |
CTD |
PMID:30547786 |
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NCBI chr 6:39,679,116...39,774,033
Ensembl chr 6:39,679,082...39,774,031
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G |
Rxra |
retinoid X receptor alpha |
multiple interactions |
ISO |
Oleic Acid binds to and results in increased activity of RXRA protein |
CTD |
PMID:16731579 PMID:27131391 |
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NCBI chr 3:10,989,832...11,076,366
Ensembl chr 3:10,989,832...11,073,712
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G |
Scd |
stearoyl-CoA desaturase |
multiple interactions decreases expression |
ISO |
[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in decreased expression of SCD mRNA; [Farnesol analog co-treated with Oleic Acid] results in decreased expression of SCD mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of SCD mRNA; [GW 7647 co-treated with Oleic Acid] results in decreased expression of SCD mRNA; [Oleic Acid co-treated with Bezafibrate] results in increased expression of SCD1 mRNA; [Oleic Acid co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of SCD mRNA; [Oleic Acid co-treated with Fenofibrate] results in increased expression of SCD1 mRNA; [Oleic Acid co-treated with muraglitazar] results in increased expression of SCD1 mRNA; [Oleic Acid co-treated with Palmitic Acid] results in increased expression of SCD1 mRNA; [Oleic Acid co-treated with tesaglitazar] results in increased expression of SCD1 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of SCD mRNA; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of SCD mRNA; [perfluorodecanoic acid co-treated with Oleic Acid] results in increased expression of SCD mRNA; Coptidis rhizoma extract inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of SCD1 mRNA] Oleic Acid results in decreased expression of SCD mRNA [Starch co-treated with Oleic Acid] results in increased expression of SCD1 mRNA; [Sucrose co-treated with Oleic Acid] results in increased expression of SCD1 mRNA |
CTD |
PMID:24534255 PMID:26895660 PMID:30547786 PMID:30611723 PMID:36423729 PMID:38092172 PMID:38103844 More...
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NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562
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G |
Scp2 |
sterol carrier protein 2 |
multiple interactions |
ISO |
[GW 4064 co-treated with Oleic Acid] results in decreased expression of SCP2 mRNA |
CTD |
PMID:30611723 |
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NCBI chr 5:122,806,949...122,881,259
Ensembl chr 5:122,776,549...122,881,287
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G |
Serpine1 |
serpin family E member 1 |
multiple interactions |
ISO |
[Oleic Acid co-treated with INS protein] results in increased expression of SERPINE1 mRNA; [Oleic Acid co-treated with INS protein] results in increased expression of SERPINE1 protein; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of SERPINE1 mRNA; Bezafibrate inhibits the reaction [[Oleic Acid co-treated with INS protein] results in increased expression of SERPINE1 mRNA]; Bezafibrate inhibits the reaction [[Oleic Acid co-treated with INS protein] results in increased expression of SERPINE1 protein]; Troglitazone promotes the reaction [[Oleic Acid co-treated with INS protein] results in increased expression of SERPINE1 mRNA]; Troglitazone promotes the reaction [[Oleic Acid co-treated with INS protein] results in increased expression of SERPINE1 protein] |
CTD |
PMID:11292061 PMID:30547786 |
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NCBI chr12:19,601,272...19,611,657
Ensembl chr12:19,601,272...19,611,657
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G |
Sirt1 |
sirtuin 1 |
increases expression multiple interactions decreases activity |
EXP ISO |
Oleic Acid results in increased expression of SIRT1 protein 6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide inhibits the reaction [NAD promotes the reaction [Oleic Acid results in decreased activity of SIRT1 protein]]; N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride inhibits the reaction [Oleic Acid results in decreased activity of SIRT1 protein]; NAD promotes the reaction [Oleic Acid results in decreased activity of SIRT1 protein] [Ethanol co-treated with Oleic Acid co-treated with Palmitic Acid] results in decreased expression of SIRT1 protein |
CTD |
PMID:24349266 PMID:25536389 PMID:26854922 |
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NCBI chr20:25,307,225...25,329,273
Ensembl chr20:25,306,917...25,329,260
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G |
Sirt4 |
sirtuin 4 |
decreases expression |
EXP |
Oleic Acid results in decreased expression of SIRT4 mRNA |
CTD |
PMID:24349266 |
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NCBI chr12:41,125,533...41,139,440
Ensembl chr12:41,131,262...41,139,439
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G |
Slc13a1 |
solute carrier family 13 member 1 |
multiple interactions |
ISO |
PPARA protein promotes the reaction [Oleic Acid results in decreased expression of SLC13A1 mRNA] |
CTD |
PMID:18489776 |
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NCBI chr 4:52,569,179...52,647,126
Ensembl chr 4:52,569,375...52,647,099
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G |
Slc16a9 |
solute carrier family 16, member 9 |
multiple interactions |
ISO |
PPARA protein promotes the reaction [Oleic Acid results in decreased expression of SLC16A9 mRNA] |
CTD |
PMID:18489776 |
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NCBI chr20:18,335,862...18,377,125
Ensembl chr20:18,335,862...18,377,022
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G |
Slc25a11 |
solute carrier family 25 member 11 |
decreases expression |
EXP |
Oleic Acid results in decreased expression of SLC25A11 mRNA |
CTD |
PMID:24349266 |
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NCBI chr10:55,357,590...55,360,441
Ensembl chr10:55,357,597...55,360,410
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G |
Slc25a20 |
solute carrier family 25 member 20 |
increases expression multiple interactions |
EXP ISO |
Oleic Acid results in increased expression of SLC25A20 protein [Farnesol analog co-treated with Oleic Acid] results in increased expression of SLC25A20 mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of SLC25A20 mRNA; [GW 7647 co-treated with Oleic Acid] results in increased expression of SLC25A20 mRNA |
CTD |
PMID:24349266 PMID:30611723 |
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NCBI chr 8:109,365,056...109,386,512
Ensembl chr 8:109,365,002...109,386,512
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G |
Slc25a22 |
solute carrier family 25 member 22 |
decreases expression |
EXP |
Oleic Acid results in decreased expression of SLC25A22 mRNA |
CTD |
PMID:24349266 |
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NCBI chr 1:196,528,471...196,536,398
Ensembl chr 1:196,528,472...196,536,331
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G |
Slc27a1 |
solute carrier family 27 member 1 |
multiple interactions |
ISO |
[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in decreased expression of SLC27A1 mRNA; [Farnesol analog co-treated with Oleic Acid] results in increased expression of SLC27A1 mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of SLC27A1 mRNA; [GW 7647 co-treated with Oleic Acid] results in decreased expression of SLC27A1 mRNA |
CTD |
PMID:30611723 |
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NCBI chr16:18,278,984...18,300,173
Ensembl chr16:18,278,984...18,296,063
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G |
Slc27a2 |
solute carrier family 27 member 2 |
multiple interactions |
ISO |
[6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in increased expression of SLC27A2 mRNA; [GW 4064 co-treated with Oleic Acid] results in decreased expression of SLC27A2 mRNA; [GW 7647 co-treated with Oleic Acid] results in increased expression of SLC27A2 mRNA; [Oleic Acid co-treated with Palmitic Acid] results in decreased expression of SLC27A2 mRNA |
CTD |
PMID:30611723 PMID:38092172 |
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NCBI chr 3:113,804,728...113,842,208
Ensembl chr 3:113,804,728...113,842,208
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G |
Slc27a4 |
solute carrier family 27 member 4 |
multiple interactions |
ISO |
PPARA protein promotes the reaction [Oleic Acid results in increased expression of SLC27A4 mRNA] |
CTD |
PMID:18489776 |
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NCBI chr 3:13,075,022...13,087,943
Ensembl chr 3:13,075,022...13,087,943
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G |
Slc2a1 |
solute carrier family 2 member 1 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of SLC2A1 mRNA |
CTD |
PMID:30547786 |
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NCBI chr 5:132,717,196...132,745,416
Ensembl chr 5:132,717,196...132,745,416
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G |
Slc2a2 |
solute carrier family 2 member 2 |
increases expression multiple interactions |
ISO |
Oleic Acid results in increased expression of SLC2A2 mRNA [Palmitic Acid co-treated with Oleic Acid] results in decreased expression of SLC2A2 mRNA; Bezafibrate inhibits the reaction [Oleic Acid results in increased expression of SLC2A2 mRNA] |
CTD |
PMID:12048068 PMID:30547786 |
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NCBI chr 2:111,609,798...111,639,930
Ensembl chr 2:111,611,774...111,639,933
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G |
Slc6a3 |
solute carrier family 6 member 3 |
multiple interactions |
ISO |
PPARA protein promotes the reaction [Oleic Acid results in increased expression of SLC6A3 mRNA] |
CTD |
PMID:18489776 |
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NCBI chr 1:29,709,443...29,750,413
Ensembl chr 1:29,709,443...29,750,413
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G |
Smim20 |
small integral membrane protein 20 |
increases expression |
ISO |
Oleic Acid results in increased expression of SMIM20 mRNA |
CTD |
PMID:30524225 |
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NCBI chr14:57,711,304...57,722,681
Ensembl chr14:57,711,307...57,722,681
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G |
Snap23 |
synaptosome associated protein 23 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of SNAP23 mRNA; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of SNAP23 mRNA |
CTD |
PMID:30547786 |
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NCBI chr 3:107,514,088...107,546,177
Ensembl chr 3:107,514,131...107,544,320
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G |
Socs1 |
suppressor of cytokine signaling 1 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of SOCS1 mRNA |
CTD |
PMID:30547786 |
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NCBI chr10:4,882,651...4,884,342
Ensembl chr10:4,882,560...4,884,383
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G |
Socs2 |
suppressor of cytokine signaling 2 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of SOCS2 mRNA; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of SOCS2 mRNA |
CTD |
PMID:30547786 |
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NCBI chr 7:30,006,360...30,045,161
Ensembl chr 7:30,008,578...30,043,548
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G |
Socs3 |
suppressor of cytokine signaling 3 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of SOCS3 mRNA |
CTD |
PMID:30547786 |
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NCBI chr10:103,193,909...103,197,322
Ensembl chr10:103,193,537...103,197,787
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G |
Sod1 |
superoxide dismutase 1 |
multiple interactions decreases secretion decreases expression |
ISO |
Diethylhexyl Phthalate promotes the reaction [Oleic Acid results in decreased secretion of SOD1 protein]; gastrodin inhibits the reaction [Oleic Acid results in decreased expression of SOD1 mRNA] |
CTD |
PMID:26634892 PMID:27996362 |
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NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
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G |
Sod2 |
superoxide dismutase 2 |
increases expression multiple interactions |
EXP ISO |
Oleic Acid results in increased expression of SOD2 mRNA [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of SOD2 mRNA |
CTD |
PMID:24349266 PMID:30547786 |
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NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
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G |
Sqstm1 |
sequestosome 1 |
increases expression multiple interactions |
ISO |
Oleic Acid results in increased expression of SQSTM1 protein [Palmitic Acid co-treated with Oleic Acid] results in increased expression of SQSTM1 protein; Escin inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in increased expression of SQSTM1 protein]; Metformin inhibits the reaction [Oleic Acid results in increased expression of SQSTM1 protein]; necrostatin-1 inhibits the reaction [Oleic Acid results in increased expression of SQSTM1 protein]; PGAM5 protein promotes the reaction [Oleic Acid results in increased expression of SQSTM1 protein]; qidan inhibits the reaction [Oleic Acid results in increased expression of SQSTM1 protein] |
CTD |
PMID:36273635 PMID:36592823 PMID:36905866 |
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NCBI chr10:34,525,517...34,536,670
Ensembl chr10:34,525,519...34,536,673
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G |
Srebf1 |
sterol regulatory element binding transcription factor 1 |
increases expression multiple interactions decreases expression |
EXP ISO |
Oleic Acid results in increased expression of SREBF1 mRNA Oleic Acid results in increased expression of SREBF1 mRNA; Oleic Acid results in increased expression of SREBF1 protein [N-(oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide hydrochloride co-treated with Oleic Acid] results in increased expression of SREBF1 mRNA [Oleic Acid co-treated with Palmitic Acid co-treated with Ethanol] results in increased expression of SREBF1 protein; [Oleic Acid co-treated with Palmitic Acid] results in increased expression of SREBF1 mRNA; quercetin 3-O-glucuronide inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of SREBF1 mRNA]; sophocarpine inhibits the reaction [Oleic Acid results in increased expression of SREBF1 mRNA] [6-(4-chlorophenyl)imidazo(2,1-b)(1,3)thiazole-5-carbaldehyde O-(3,4-dichlorobenzyl)oxime co-treated with Oleic Acid] results in decreased expression of SREBF1 mRNA; [cyhalothrin co-treated with Oleic Acid] results in increased expression of SREBF1 protein; [GW 4064 co-treated with Oleic Acid] results in decreased expression of SREBF1 mRNA; [GW 7647 co-treated with Oleic Acid] results in decreased expression of SREBF1 mRNA; [Oleic Acid co-treated with Dibutyl Phthalate] results in increased expression of SREBF1 mRNA; [Oleic Acid co-treated with Dibutyl Phthalate] results in increased expression of SREBF1 protein; [Oleic Acid co-treated with Dichlorodiphenyl Dichloroethylene] results in decreased expression of SREBF1 mRNA; [Oleic Acid co-treated with Palmitic Acid] results in increased expression of SREBF1 mRNA; [Oleic Acid co-treated with Palmitic Acid] results in increased expression of SREBF1 protein; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of SREBF1 mRNA; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of SREBF1 protein; Benzo(a)pyrene inhibits the reaction [Estradiol inhibits the reaction [Oleic Acid results in increased expression of SREBF1 mRNA]]; Benzo(a)pyrene inhibits the reaction [Estradiol inhibits the reaction [Oleic Acid results in increased expression of SREBF1 protein]]; Coptidis rhizoma extract inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of SREBF1 mRNA]; Dibutyl Phthalate inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of SREBF1 mRNA]; Diethylhexyl Phthalate promotes the reaction [Oleic Acid results in increased expression of SREBF1 protein]; Escin inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in increased expression of SREBF1 mRNA]; Escin inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in increased expression of SREBF1 protein]; Estradiol inhibits the reaction [Oleic Acid results in increased expression of SREBF1 mRNA]; Estradiol inhibits the reaction [Oleic Acid results in increased expression of SREBF1 protein]; GW 6471 inhibits the reaction [[Oleic Acid co-treated with Dibutyl Phthalate] results in increased expression of SREBF1 protein]; isosilybin inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of SREBF1 protein]; Metformin inhibits the reaction [[cyhalothrin co-treated with Oleic Acid] results in increased expression of SREBF1 protein]; Plant Extracts inhibits the reaction [Oleic Acid results in decreased expression of SREBF1 mRNA]; Plant Extracts inhibits the reaction [Oleic Acid results in decreased expression of SREBF1 protein] Oleic Acid results in decreased expression of SREBF1 mRNA; Oleic Acid results in decreased expression of SREBF1 protein |
CTD |
PMID:15949695 PMID:23395669 PMID:23603006 PMID:26190035 PMID:26854922 PMID:27996362 PMID:30165350 PMID:30611723 PMID:31730885 PMID:33508418 PMID:36347319 PMID:36529352 PMID:36905866 PMID:38092172 PMID:38103844 More...
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NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650
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G |
Tbxa2r |
thromboxane A2 receptor |
multiple interactions |
EXP |
Phenolsulfonphthalein inhibits the reaction [Oleic Acid results in increased expression of TBXA2R mRNA] |
CTD |
PMID:11263294 |
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NCBI chr 7:8,383,347...8,390,753
Ensembl chr 7:8,383,378...8,388,176
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G |
Tecr |
trans-2,3-enoyl-CoA reductase |
multiple interactions |
ISO |
[GW 4064 co-treated with Oleic Acid] results in decreased expression of TECR mRNA |
CTD |
PMID:30611723 |
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NCBI chr19:24,526,700...24,568,168
Ensembl chr19:24,541,615...24,568,168
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G |
Tfam |
transcription factor A, mitochondrial |
multiple interactions |
ISO |
[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of TFAM mRNA; FOXO1 protein affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in decreased expression of TFAM mRNA] |
CTD |
PMID:26847930 |
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NCBI chr20:17,356,243...17,368,293
Ensembl chr20:17,356,197...17,368,292
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G |
Tfrc |
transferrin receptor |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid] results in increased expression of TFRC protein; ginkgolide B inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in increased expression of TFRC protein] |
CTD |
PMID:32976958 |
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NCBI chr11:68,163,413...68,185,257
Ensembl chr11:68,163,413...68,185,257
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G |
Tgfb1 |
transforming growth factor, beta 1 |
multiple interactions increases expression |
ISO |
Sorafenib inhibits the reaction [Oleic Acid results in increased expression of TGFB1 protein] |
CTD |
PMID:32918399 |
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NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
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G |
Tgfb2 |
transforming growth factor, beta 2 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of TGFB2 mRNA |
CTD |
PMID:30547786 |
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NCBI chr13:98,160,075...98,261,771
Ensembl chr13:98,160,087...98,261,405
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G |
Thrsp |
thyroid hormone responsive |
multiple interactions decreases expression |
ISO |
Bezafibrate promotes the reaction [Oleic Acid results in decreased expression of THRSP mRNA]; Fenofibrate promotes the reaction [Oleic Acid results in decreased expression of THRSP mRNA] |
CTD |
PMID:24534255 |
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NCBI chr 1:151,723,415...151,727,740
Ensembl chr 1:151,723,086...151,728,075
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G |
Timp1 |
TIMP metallopeptidase inhibitor 1 |
multiple interactions increases expression |
ISO |
[Oleic Acid co-treated with Palmitic Acid] results in increased expression of TIMP1 mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of TIMP1 mRNA; Sorafenib inhibits the reaction [Oleic Acid results in increased expression of TIMP1 mRNA] |
CTD |
PMID:26187275 PMID:30547786 PMID:32918399 |
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NCBI chr X:1,212,969...1,217,714
Ensembl chr X:1,212,972...1,217,664
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G |
Tnf |
tumor necrosis factor |
decreases response to substance increases expression multiple interactions |
ISO EXP |
Oleic Acid results in decreased susceptibility to TNF protein Oleic Acid results in increased expression of TNF mRNA; Oleic Acid results in increased expression of TNF protein [Oleic Acid co-treated with Palmitic Acid] results in increased expression of TNF protein; BACE1 protein affects the reaction [SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of TNF protein]]; MIR497 affects the reaction [SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of TNF protein]]; SNHG14 affects the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of TNF protein] [Oleic Acid co-treated with Palmitic Acid] results in increased expression of TNF protein; Dexamethasone inhibits the reaction [Oleic Acid results in increased expression of TNF mRNA]; Dexamethasone inhibits the reaction [Oleic Acid results in increased expression of TNF protein]; gossypin inhibits the reaction [Oleic Acid results in increased expression of TNF mRNA]; gossypin inhibits the reaction [Oleic Acid results in increased expression of TNF protein]; quercetin 3-O-glucuronide inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of TNF protein] [Oleic Acid co-treated with Palmitic Acid] results in increased expression of TNF mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of ABCA1 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of ACSL1 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of AGPAT2 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of AGPAT5 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of AHR mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of ARG1 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of B4GALT5 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of CAT mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of CXCL2 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of CXCL3 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of DYNC1H1 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of DYNC1I1 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of ENO3 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of ERLIN1 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of FOXA1 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of GLUD1 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of GLUD2 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of HSDL2 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of IL1A mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of LAMB1 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of NR1H4 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of PEBP1 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of PKLR mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of PLD1 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of PNPLA3 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of PPARD mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of PRKAA1 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of RAB18 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of RHEB mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of RHOB mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of SCD mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of SERPINE1 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of SLC2A1 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of SOCS1 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of SOD2 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of TGFB2 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of TNFAIP2 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of TUBB2A mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of UGCG mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of VAMP4 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of VCAN mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in decreased expression of CPT1A protein; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in decreased expression of DST mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of ACSL4 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of ANGPTL4 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of ANXA2 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of CIDEC protein; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of CPT1A mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of CXCL8 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of CYP24A1 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of CYP26A1 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of FGF21 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of FLOT1 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of HIF1A protein; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of HILPDA protein; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of JAK1 protein; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of LDLR mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of MAP3K8 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of MAP4K4 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of MTTP mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of PDK4 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of PDK4 protein; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of PLIN2 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of PLIN2 protein; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of PPARA mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of ROCK2 protein; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of SNAP23 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of SOCS2 mRNA; [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] results in increased expression of SOCS3 mRNA; Coptidis rhizoma extract inhibits the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of TNF mRNA]; dorsomorphin inhibits the reaction [gastrodin inhibits the reaction [Oleic Acid results in increased expression of TNF mRNA]]; gastrodin inhibits the reaction [Oleic Acid results in increased expression of TNF mRNA]; Quercetin inhibits the reaction [Oleic Acid results in increased expression of TNF mRNA]; Quercetin inhibits the reaction [Oleic Acid results in increased expression of TNF protein]; Silymarin inhibits the reaction [Oleic Acid results in increased expression of TNF mRNA]; Silymarin inhibits the reaction [Oleic Acid results in increased expression of TNF protein]; Sorafenib inhibits the reaction [Oleic Acid results in increased expression of TNF protein]; Vitamin E inhibits the reaction [Oleic Acid results in increased expression of TNF mRNA]; Vitamin E inhibits the reaction [Oleic Acid results in increased expression of TNF protein] |
CTD |
PMID:22683933 PMID:23348005 PMID:26190035 PMID:26634892 PMID:30547786 PMID:32918399 PMID:37009739 PMID:37696682 PMID:38103844 More...
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NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
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G |
Tnfaip2 |
TNF alpha induced protein 2 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of TNFAIP2 mRNA |
CTD |
PMID:30547786 |
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NCBI chr 6:130,476,832...130,489,914
Ensembl chr 6:130,476,889...130,489,914
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G |
Tp53 |
tumor protein p53 |
multiple interactions |
ISO |
3-N-1(spermine)-7, 24-dihydroxy-5-cholestane 24-sulfate inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in increased expression of TP53 mRNA]; [Palmitic Acid co-treated with Oleic Acid] results in increased expression of TP53 mRNA |
CTD |
PMID:32369900 |
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NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
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G |
Tubb2a |
tubulin, beta 2A class IIa |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of TUBB2A mRNA |
CTD |
PMID:30547786 |
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NCBI chr17:30,796,842...30,800,713
Ensembl chr17:30,747,503...30,800,714
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G |
Tufm |
Tu translation elongation factor, mitochondrial |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid] affects the expression of TUFM mRNA |
CTD |
PMID:30547786 |
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NCBI chr 1:181,073,788...181,077,395
Ensembl chr 1:181,073,788...181,077,395
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Ucp2 |
uncoupling protein 2 |
increases expression multiple interactions decreases expression |
EXP |
Oleic Acid results in increased expression of UCP2 mRNA [Oleic Acid co-treated with Palmitic Acid co-treated with Ethanol] results in decreased expression of UCP2 protein; [Oleic Acid co-treated with Palmitic Acid] results in decreased expression of UCP2 mRNA; [Oleic Acid co-treated with Palmitic Acid] results in increased expression of UCP2 mRNA; [Oleic Acid co-treated with Palmitic Acid] results in increased expression of UCP2 protein; tetrabromobisphenol A promotes the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of UCP2 mRNA]; tetrabromobisphenol A promotes the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of UCP2 protein]; Triiodothyronine promotes the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of UCP2 mRNA]; Triiodothyronine promotes the reaction [[Oleic Acid co-treated with Palmitic Acid] results in increased expression of UCP2 protein] Oleic Acid results in decreased expression of UCP2 mRNA |
CTD |
PMID:11341955 PMID:12588052 PMID:24349266 PMID:25048947 PMID:26854922 |
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NCBI chr 1:154,839,242...154,845,612
Ensembl chr 1:154,839,209...154,845,611
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Ucp3 |
uncoupling protein 3 |
increases expression multiple interactions |
EXP ISO |
Oleic Acid results in increased expression of UCP3 mRNA Oleic Acid inhibits the reaction [troglitazone results in decreased expression of UCP3 mRNA] |
CTD |
PMID:11056218 PMID:12630940 |
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NCBI chr 1:154,815,777...154,828,764
Ensembl chr 1:154,815,777...154,828,762
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G |
Ugcg |
UDP-glucose ceramide glucosyltransferase |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of UGCG mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of UGCG mRNA |
CTD |
PMID:30547786 |
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NCBI chr 5:74,032,978...74,065,701
Ensembl chr 5:74,032,978...74,065,393
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G |
Vamp4 |
vesicle-associated membrane protein 4 |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of VAMP4 mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of VAMP4 mRNA |
CTD |
PMID:30547786 |
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NCBI chr13:74,919,872...74,942,791
Ensembl chr13:74,919,880...74,933,686
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G |
Vcan |
versican |
multiple interactions |
ISO |
[Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of VCAN mRNA; [Palmitic Acid co-treated with Oleic Acid] affects the expression of VCAN mRNA |
CTD |
PMID:30547786 |
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NCBI chr 2:20,761,718...20,860,637
Ensembl chr 2:20,761,718...20,860,637
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G |
Vnn1 |
vanin 1 |
multiple interactions |
ISO |
Oleic Acid promotes the reaction [[Vehicle Emissions results in increased abundance of Particulate Matter] which results in increased expression of VNN1 mRNA] |
CTD |
PMID:31340670 |
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NCBI chr 1:21,537,084...21,547,395
Ensembl chr 1:21,537,094...21,547,395
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G |
Xbp1 |
X-box binding protein 1 |
multiple interactions |
ISO |
3-N-1(spermine)-7, 24-dihydroxy-5-cholestane 24-sulfate inhibits the reaction [[Palmitic Acid co-treated with Oleic Acid] results in increased splicing of XBP1 mRNA]; [Palmitic Acid co-treated with Oleic Acid] results in increased splicing of XBP1 mRNA Oleic Acid inhibits the reaction [[Palmitates co-treated with bisphenol A] results in increased splicing of XBP1 mRNA] |
CTD |
PMID:32369900 PMID:32976987 |
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NCBI chr14:80,390,629...80,395,713
Ensembl chr14:80,390,643...80,395,693
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G |
Yap1 |
Yes1 associated transcriptional regulator |
affects localization |
ISO |
Oleic Acid affects the localization of YAP1 protein |
CTD |
PMID:37117602 |
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NCBI chr 8:5,095,705...5,166,808
Ensembl chr 8:5,095,722...5,167,010
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G |
Abcb1a |
ATP binding cassette subfamily B member 1A |
increases export |
ISO |
ABCB1 protein results in increased export of N-oleoylethanolamine |
CTD |
PMID:30102254 |
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NCBI chr 4:25,357,467...25,529,941
Ensembl chr 4:25,158,362...25,442,709
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G |
Ppara |
peroxisome proliferator activated receptor alpha |
increases response to substance multiple interactions |
ISO |
PPARA results in increased susceptibility to N-oleoylethanolamine N-oleoylethanolamine binds to and results in increased activity of PPARA protein |
CTD |
PMID:17906680 |
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NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
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G |
Ptgs2 |
prostaglandin-endoperoxide synthase 2 |
decreases expression |
ISO |
N-oleoylethanolamine results in decreased expression of PTGS2 protein |
CTD |
PMID:17906680 |
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NCBI chr13:62,163,936...62,172,193
Ensembl chr13:62,163,932...62,172,188
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Abca1 |
ATP binding cassette subfamily A member 1 |
increases degradation multiple interactions increases phosphorylation |
ISO |
palmitoleic acid results in increased degradation of ABCA1 protein palmitoleic acid inhibits the reaction [APOA1 protein affects the reaction [ABCA1 protein results in increased transport of Cholesterol]]; palmitoleic acid inhibits the reaction [APOA1 protein affects the reaction [ABCA1 protein results in increased transport of Phospholipids]] palmitoleic acid results in increased phosphorylation of ABCA1 protein |
CTD |
PMID:16118212 |
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NCBI chr 5:67,678,267...67,801,162
Ensembl chr 5:67,681,297...67,801,170
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Apoa1 |
apolipoprotein A1 |
multiple interactions |
ISO |
palmitoleic acid inhibits the reaction [APOA1 protein affects the reaction [ABCA1 protein results in increased transport of Cholesterol]]; palmitoleic acid inhibits the reaction [APOA1 protein affects the reaction [ABCA1 protein results in increased transport of Phospholipids]] |
CTD |
PMID:16118212 |
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NCBI chr 8:46,527,251...46,529,035
Ensembl chr 8:46,527,144...46,529,035
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G |
Il6 |
interleukin 6 |
increases expression |
ISO |
palmitoleic acid results in increased expression of IL6 mRNA |
CTD |
PMID:30524225 |
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NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
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G |
Ins2 |
insulin 2 |
multiple interactions |
ISO |
[1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] results in increased abundance of palmitoleic acid analog |
CTD |
PMID:26820058 |
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NCBI chr 1:197,843,277...197,992,522
Ensembl chr 1:197,843,281...197,864,775
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G |
Pck1 |
phosphoenolpyruvate carboxykinase 1 |
multiple interactions |
ISO |
[Glucose deficiency co-treated with palmitoleic acid] results in increased expression of PCK1 mRNA |
CTD |
PMID:8536680 |
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NCBI chr 3:161,930,256...161,936,205
Ensembl chr 3:161,930,256...161,936,191
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Pon1 |
paraoxonase 1 |
multiple interactions decreases activity |
ISO |
palmitoleic acid inhibits the reaction [[Ascorbic Acid co-treated with Copper Sulfate] results in decreased activity of PON1 protein]; palmitoleic acid inhibits the reaction [PON1 protein results in increased hydrolysis of Paraoxon] palmitoleic acid results in decreased activity of PON1 protein |
CTD |
PMID:12871208 PMID:15375178 |
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NCBI chr 4:33,294,737...33,325,759
Ensembl chr 4:33,294,722...33,321,360
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G |
Cyp4a1 |
cytochrome P450, family 4, subfamily a, polypeptide 1 |
increases expression |
EXP |
4-pentenoic acid results in increased expression of CYP4A1 mRNA |
CTD |
PMID:12883083 |
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NCBI chr 5:129,123,323...129,137,464
Ensembl chr 5:129,123,336...129,137,464
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G |
Hprt1 |
hypoxanthine phosphoribosyltransferase 1 |
increases expression |
EXP |
4-pentenoic acid results in increased expression of HPRT1 mRNA |
CTD |
PMID:12883083 |
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NCBI chr X:132,736,175...132,768,149
Ensembl chr X:132,736,096...132,768,154
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G |
Jun |
Jun proto-oncogene, AP-1 transcription factor subunit |
increases expression |
EXP |
4-pentenoic acid results in increased expression of JUN mRNA |
CTD |
PMID:12883083 |
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NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
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G |
Rgn |
regucalcin |
decreases expression |
EXP |
4-pentenoic acid results in decreased expression of RGN mRNA |
CTD |
PMID:12883083 |
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NCBI chr X:1,619,030...1,634,456
Ensembl chr X:1,619,032...1,634,450
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G |
Cnr1 |
cannabinoid receptor 1 |
affects binding |
ISO |
ricinoleic acid analog binds to CNR1 protein |
CTD |
PMID:16406364 |
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NCBI chr 5:48,408,543...48,436,099
Ensembl chr 5:48,408,574...48,435,099
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G |
Cnr2 |
cannabinoid receptor 2 |
multiple interactions |
ISO |
ricinoleic acid analog binds to and affects the activity of CNR2 protein |
CTD |
PMID:16406364 |
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NCBI chr 5:148,125,222...148,151,548
Ensembl chr 5:148,125,604...148,151,548
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G |
Il4 |
interleukin 4 |
multiple interactions |
ISO |
ricinoleic acid inhibits the reaction [IL4 protein results in increased expression of VCAM1 protein] |
CTD |
PMID:7544037 |
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NCBI chr10:37,771,203...37,776,750
Ensembl chr10:37,771,203...37,776,750
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G |
Ptgds |
prostaglandin D2 synthase |
affects binding |
ISO |
ricinoleic acid binds to PTGDS protein |
CTD |
PMID:26456343 |
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NCBI chr 3:8,281,899...8,284,833
Ensembl chr 3:8,281,899...8,284,833
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G |
Trpv1 |
transient receptor potential cation channel, subfamily V, member 1 |
multiple interactions |
ISO |
ricinoleic acid analog binds to and affects the activity of TRPV1 protein |
CTD |
PMID:16406364 |
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NCBI chr10:57,851,428...57,876,513
Ensembl chr10:57,851,428...57,876,513
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G |
Vcam1 |
vascular cell adhesion molecule 1 |
multiple interactions |
ISO |
ricinoleic acid inhibits the reaction [IL4 protein results in increased expression of VCAM1 protein] |
CTD |
PMID:7544037 |
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NCBI chr 2:204,038,120...204,057,852
Ensembl chr 2:204,038,114...204,057,958
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G |
Nr1h4 |
nuclear receptor subfamily 1, group H, member 4 |
increases expression |
EXP |
rosuvastatin increases Nr1h4 mRNA expression in rat kidney and liver |
RGD |
PMID:30308196 |
RGD:15042865 |
NCBI chr 7:23,846,122...23,942,085
Ensembl chr 7:23,846,122...23,942,047
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G |
Bax |
BCL2 associated X, apoptosis regulator |
multiple interactions |
EXP |
royal jelly inhibits the reaction [Fluorides results in decreased expression of BAX protein] |
CTD |
PMID:34227456 |
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NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
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G |
Bcl2 |
BCL2, apoptosis regulator |
multiple interactions |
ISO EXP |
royal jelly inhibits the reaction [Nicotine results in decreased expression of BCL2 mRNA] royal jelly inhibits the reaction [Fluorides results in increased expression of BCL2 protein] |
CTD |
PMID:30896085 PMID:34227456 |
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NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
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G |
Bdnf |
brain-derived neurotrophic factor |
multiple interactions |
EXP |
royal jelly inhibits the reaction [Fluorides results in decreased expression of BDNF protein] |
CTD |
PMID:34227456 |
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NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615
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G |
Casp3 |
caspase 3 |
multiple interactions |
ISO EXP |
royal jelly inhibits the reaction [Nicotine results in increased expression of CASP3 mRNA] royal jelly inhibits the reaction [Fluorides results in decreased expression of CASP3 protein] |
CTD |
PMID:30896085 PMID:34227456 |
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NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
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G |
Casp6 |
caspase 6 |
multiple interactions |
EXP |
royal jelly inhibits the reaction [Fluorides results in decreased expression of CASP6 protein] |
CTD |
PMID:34227456 |
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NCBI chr 2:218,466,063...218,478,503
Ensembl chr 2:218,466,076...218,478,502
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G |
Casp9 |
caspase 9 |
multiple interactions |
EXP |
royal jelly inhibits the reaction [Fluorides results in decreased expression of CASP9 protein] |
CTD |
PMID:34227456 |
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NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
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G |
Cat |
catalase |
multiple interactions |
EXP ISO |
royal jelly inhibits the reaction [Cisplatin results in decreased activity of CAT protein]; royal jelly inhibits the reaction [Fluorides results in decreased activity of CAT protein] royal jelly inhibits the reaction [Nicotine results in decreased activity of CAT protein] |
CTD |
PMID:20369241 PMID:30896085 PMID:34227456 |
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NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
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G |
Ccnd1 |
cyclin D1 |
multiple interactions |
ISO |
royal jelly inhibits the reaction [phenylhydrazine affects the expression of CCND1 mRNA] |
CTD |
PMID:35099105 |
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NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
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G |
E2f1 |
E2F transcription factor 1 |
multiple interactions |
EXP |
royal jelly inhibits the reaction [Paclitaxel results in increased expression of E2F1 mRNA] |
CTD |
PMID:27496854 |
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NCBI chr 3:143,064,535...143,075,362
Ensembl chr 3:143,049,478...143,075,361
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G |
Esr1 |
estrogen receptor 1 |
multiple interactions increases activity affects binding |
ISO |
Estradiol inhibits the reaction [royal jelly binds to ESR1 protein]; royal jelly binds to and results in increased activity of ESR1 protein; royal jelly inhibits the reaction [Estradiol binds to ESR1 protein] royal jelly results in increased activity of ESR1 protein |
CTD |
PMID:15946813 PMID:17287592 |
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NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
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G |
Esr2 |
estrogen receptor 2 |
multiple interactions affects binding |
ISO |
Estradiol inhibits the reaction [royal jelly binds to ESR2 protein]; royal jelly binds to and results in increased activity of ESR2 protein; royal jelly inhibits the reaction [Estradiol binds to ESR2 protein] |
CTD |
PMID:15946813 PMID:17287592 |
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NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919
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G |
Gsk3b |
glycogen synthase kinase 3 beta |
multiple interactions |
EXP |
royal jelly inhibits the reaction [Fluorides results in increased expression of GSK3B protein] |
CTD |
PMID:34227456 |
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NCBI chr11:62,498,997...62,648,665
Ensembl chr11:62,504,316...62,648,646
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G |
Ins1 |
insulin 1 |
multiple interactions |
EXP |
royal jelly inhibits the reaction [Fructose results in increased expression of INS1 protein] |
CTD |
PMID:18981581 |
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NCBI chr 1:251,244,973...251,245,540
Ensembl chr 1:251,244,973...251,245,536
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G |
Myc |
MYC proto-oncogene, bHLH transcription factor |
multiple interactions decreases expression |
ISO EXP |
royal jelly inhibits the reaction [phenylhydrazine results in decreased expression of MYC mRNA] royal jelly inhibits the reaction [Paclitaxel results in decreased expression of MYC mRNA] royal jelly results in decreased expression of MYC mRNA |
CTD |
PMID:27496854 PMID:35099105 |
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NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
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G |
Nfe2l2 |
NFE2 like bZIP transcription factor 2 |
multiple interactions |
EXP |
royal jelly inhibits the reaction [Fluorides results in decreased expression of NFE2L2 protein] |
CTD |
PMID:34227456 |
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NCBI chr 3:60,594,239...60,621,712
Ensembl chr 3:60,594,242...60,621,737
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G |
Pcna |
proliferating cell nuclear antigen |
multiple interactions |
ISO |
royal jelly inhibits the reaction [Nicotine results in decreased expression of PCNA protein] |
CTD |
PMID:30896085 |
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NCBI chr 3:119,499,039...119,502,911
Ensembl chr 3:119,498,810...119,502,995
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G |
Rela |
RELA proto-oncogene, NF-kB subunit |
multiple interactions |
EXP |
royal jelly inhibits the reaction [Fluorides results in increased expression of RELA protein] |
CTD |
PMID:34227456 |
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NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
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G |
Tff1 |
trefoil factor 1 |
increases expression |
ISO |
royal jelly results in increased expression of TFF1 mRNA |
CTD |
PMID:15946813 |
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NCBI chr20:9,235,736...9,239,597
Ensembl chr20:9,235,736...9,239,597
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G |
Tp53 |
tumor protein p53 |
multiple interactions |
ISO |
royal jelly inhibits the reaction [Nicotine results in increased expression of TRP53 mRNA] |
CTD |
PMID:30896085 |
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NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
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G |
Vegfa |
vascular endothelial growth factor A |
increases expression |
ISO EXP |
royal jelly results in increased expression of VEGFA mRNA |
CTD |
PMID:15946813 PMID:17287592 |
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NCBI chr 9:14,955,300...14,970,641
Ensembl chr 9:14,955,300...14,970,641
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G |
Abcb11 |
ATP binding cassette subfamily B member 11 |
affects expression |
EXP |
Soybean Oil affects the expression of ABCB11 mRNA |
CTD |
PMID:15770074 |
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NCBI chr 3:54,016,854...54,112,797
Ensembl chr 3:54,017,127...54,112,730
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G |
Abcb1b |
ATP-binding cassette, sub-family B member 1B |
affects expression |
EXP |
Soybean Oil affects the expression of ABCB1B mRNA |
CTD |
PMID:15770074 |
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NCBI chr 4:25,242,761...25,325,194
Ensembl chr 4:25,242,798...25,325,199
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G |
Abcb4 |
ATP binding cassette subfamily B member 4 |
affects expression |
EXP |
Soybean Oil affects the expression of ABCB4 mRNA |
CTD |
PMID:15770074 |
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NCBI chr 4:25,150,998...25,209,489
Ensembl chr 4:25,151,953...25,209,202
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G |
Abcc1 |
ATP binding cassette subfamily C member 1 |
affects expression |
EXP |
Soybean Oil affects the expression of ABCC1 mRNA |
CTD |
PMID:15770074 |
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NCBI chr10:528,961...655,179
Ensembl chr10:531,812...655,114
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G |
Abcc2 |
ATP binding cassette subfamily C member 2 |
affects expression |
EXP |
Soybean Oil affects the expression of ABCC2 mRNA |
CTD |
PMID:15770074 |
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NCBI chr 1:242,664,657...242,723,239
Ensembl chr 1:242,664,657...242,723,238
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G |
Abcc5 |
ATP binding cassette subfamily C member 5 |
affects expression |
EXP |
Soybean Oil affects the expression of ABCC5 mRNA |
CTD |
PMID:15770074 |
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NCBI chr11:80,473,809...80,567,257
Ensembl chr11:80,473,872...80,567,253
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G |
Abcc6 |
ATP binding cassette subfamily C member 6 |
affects expression |
EXP |
Soybean Oil affects the expression of ABCC6 mRNA |
CTD |
PMID:15770074 |
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NCBI chr 1:96,447,224...96,501,464
Ensembl chr 1:96,447,251...96,501,464
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G |
Acat1 |
acetyl-CoA acetyltransferase 1 |
decreases activity |
EXP |
Soybean Oil results in decreased activity of ACAT1 protein |
CTD |
PMID:12559476 |
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NCBI chr 8:53,979,813...54,008,861
Ensembl chr 8:53,979,813...54,008,855
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G |
Bcl2 |
BCL2, apoptosis regulator |
increases expression |
EXP |
Soybean Oil results in increased expression of BCL2 protein |
CTD |
PMID:15309441 |
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NCBI chr13:22,689,783...22,853,920
Ensembl chr13:22,684,989...22,853,743 Ensembl chr13:22,684,989...22,853,743
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G |
Cat |
catalase |
increases activity |
EXP |
Soybean Oil results in increased activity of CAT protein |
CTD |
PMID:12781854 |
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NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
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G |
Ccnd1 |
cyclin D1 |
increases expression |
EXP |
Soybean Oil results in increased expression of CCND1 mRNA |
CTD |
PMID:21088903 |
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NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
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G |
Cyp4a1 |
cytochrome P450, family 4, subfamily a, polypeptide 1 |
affects expression |
EXP |
Soybean Oil affects the expression of CYP4A1 mRNA |
CTD |
PMID:16079505 |
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NCBI chr 5:129,123,323...129,137,464
Ensembl chr 5:129,123,336...129,137,464
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G |
Cyp7a1 |
cytochrome P450 family 7 subfamily A member 1 |
increases activity |
EXP |
Soybean Oil results in increased activity of CYP7A1 protein |
CTD |
PMID:12559476 |
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NCBI chr 5:19,376,979...19,386,676
Ensembl chr 5:19,376,974...19,386,688
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G |
Gstp1 |
glutathione S-transferase pi 1 |
multiple interactions |
EXP |
Soybean Oil promotes the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of GSTP1 mRNA]; Soybean Oil promotes the reaction [15-deoxy-delta(12,14)-prostaglandin J2 results in increased expression of GSTP1 protein] |
CTD |
PMID:11600134 |
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NCBI chr 1:201,337,762...201,340,230
Ensembl chr 1:201,321,672...201,340,226
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G |
Hmgcr |
3-hydroxy-3-methylglutaryl-CoA reductase |
increases activity |
EXP |
Soybean Oil results in increased activity of HMGCR protein |
CTD |
PMID:12559476 |
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NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703
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G |
Il12b |
interleukin 12B |
decreases expression |
ISO |
Soybean Oil results in decreased expression of IL12B mRNA |
CTD |
PMID:10065739 |
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NCBI chr10:28,888,832...28,903,802
Ensembl chr10:28,893,008...28,902,903
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G |
Slc22a1 |
solute carrier family 22 member 1 |
affects expression |
EXP |
Soybean Oil affects the expression of SLC22A1 mRNA |
CTD |
PMID:15770074 |
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NCBI chr 1:48,076,657...48,103,679
Ensembl chr 1:48,076,666...48,103,678
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G |
Slc22a7 |
solute carrier family 22 member 7 |
affects expression |
EXP |
Soybean Oil affects the expression of SLC22A7 mRNA |
CTD |
PMID:15770074 |
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NCBI chr 9:14,547,073...14,554,354
Ensembl chr 9:14,547,849...14,553,921
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G |
Abca1 |
ATP binding cassette subfamily A member 1 |
decreases expression |
ISO |
Triolein results in decreased expression of ABCA1 mRNA |
CTD |
PMID:18356535 |
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NCBI chr 5:67,678,267...67,801,162
Ensembl chr 5:67,681,297...67,801,170
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G |
Abcg5 |
ATP binding cassette subfamily G member 5 |
decreases expression |
ISO |
Triolein results in decreased expression of ABCG5 mRNA |
CTD |
PMID:18356535 |
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NCBI chr 6:9,965,118...9,990,563
Ensembl chr 6:9,965,118...9,990,563
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G |
Abcg8 |
ATP binding cassette subfamily G member 8 |
decreases expression |
ISO |
Triolein results in decreased expression of ABCG8 mRNA |
CTD |
PMID:18356535 |
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NCBI chr 6:9,945,629...9,964,912
Ensembl chr 6:9,945,629...9,964,912
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G |
Acaca |
acetyl-CoA carboxylase alpha |
multiple interactions |
ISO |
Triolein inhibits the reaction [SCD1 gene mutant form inhibits the reaction [Fructose results in increased expression of ACACA mRNA]]; Triolein promotes the reaction [Fructose results in increased expression of ACACA mRNA] |
CTD |
PMID:15066988 |
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NCBI chr10:69,014,261...69,276,453
Ensembl chr10:69,014,170...69,276,457
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G |
Apoa4 |
apolipoprotein A4 |
multiple interactions |
EXP |
[Taurocholic Acid co-treated with Triolein co-treated with Lecithins] results in increased expression of APOA4 protein |
CTD |
PMID:6631239 |
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NCBI chr 8:46,539,083...46,541,464
Ensembl chr 8:46,539,082...46,541,469
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G |
Apoe |
apolipoprotein E |
multiple interactions |
EXP |
[Taurocholic Acid co-treated with Triolein co-treated with Lecithins] results in decreased expression of APOE protein |
CTD |
PMID:6631239 |
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NCBI chr 1:79,353,924...79,357,852
Ensembl chr 1:79,353,916...79,357,932
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G |
App |
amyloid beta precursor protein |
multiple interactions |
EXP |
Triolein inhibits the reaction [[Dietary Fats co-treated with Cholesterol, Dietary] results in increased expression of APP protein alternative form]; Triolein inhibits the reaction [[Dietary Fats co-treated with Cholesterol, Dietary] results in increased expression of APP protein] |
CTD |
PMID:28734741 |
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NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561
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G |
Cat |
catalase |
multiple interactions |
EXP |
Triolein inhibits the reaction [[Dietary Fats co-treated with Cholesterol, Dietary] results in decreased expression of CAT mRNA] |
CTD |
PMID:28734741 |
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NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
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G |
Cyp27a1 |
cytochrome P450, family 27, subfamily a, polypeptide 1 |
decreases expression |
ISO |
Triolein results in decreased expression of CYP27A1 mRNA |
CTD |
PMID:18356535 |
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NCBI chr 9:76,264,655...76,294,551
Ensembl chr 9:76,264,860...76,294,551
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G |
Fasn |
fatty acid synthase |
multiple interactions |
ISO |
Triolein inhibits the reaction [SCD1 gene mutant form inhibits the reaction [Fructose results in increased expression of FASN mRNA]]; Triolein promotes the reaction [Fructose results in increased expression of FASN mRNA] |
CTD |
PMID:15066988 |
|
NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261
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G |
Gpx1 |
glutathione peroxidase 1 |
multiple interactions |
EXP |
Triolein inhibits the reaction [[Dietary Fats co-treated with Cholesterol, Dietary] results in decreased expression of GPX1 mRNA] |
CTD |
PMID:28734741 |
|
NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
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G |
Hmgcr |
3-hydroxy-3-methylglutaryl-CoA reductase |
increases expression |
ISO |
Triolein results in increased expression of HMGCR mRNA |
CTD |
PMID:18356535 |
|
NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703
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G |
Mttp |
microsomal triglyceride transfer protein |
increases expression |
ISO |
Triolein results in increased expression of MTTP mRNA |
CTD |
PMID:18356535 |
|
NCBI chr 2:226,613,090...226,654,239
Ensembl chr 2:226,613,090...226,654,239
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G |
Npc1l1 |
NPC1 like intracellular cholesterol transporter 1 |
decreases expression |
ISO |
Triolein results in decreased expression of NPC1L1 mRNA |
CTD |
PMID:18356535 |
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NCBI chr14:81,071,448...81,091,113
Ensembl chr14:81,071,451...81,091,113
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G |
Scd |
stearoyl-CoA desaturase |
multiple interactions |
ISO |
Triolein inhibits the reaction [SCD1 gene mutant form inhibits the reaction [Fructose results in increased abundance of Triglycerides]]; Triolein inhibits the reaction [SCD1 gene mutant form inhibits the reaction [Fructose results in increased expression of ACACA mRNA]]; Triolein inhibits the reaction [SCD1 gene mutant form inhibits the reaction [Fructose results in increased expression of FASN mRNA]]; Triolein inhibits the reaction [SCD1 gene mutant form inhibits the reaction [Fructose results in increased expression of SREBF1 mRNA]]; Triolein inhibits the reaction [SCD1 gene mutant form inhibits the reaction [Fructose results in increased expression of SREBF1 protein]] |
CTD |
PMID:15066988 |
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NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562
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G |
Sod1 |
superoxide dismutase 1 |
multiple interactions |
EXP |
Triolein inhibits the reaction [[Dietary Fats co-treated with Cholesterol, Dietary] results in decreased expression of SOD1 mRNA] |
CTD |
PMID:28734741 |
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NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
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G |
Sod2 |
superoxide dismutase 2 |
multiple interactions |
EXP |
Triolein inhibits the reaction [[Dietary Fats co-treated with Cholesterol, Dietary] results in decreased expression of SOD2 mRNA] |
CTD |
PMID:28734741 |
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NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
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G |
Srebf1 |
sterol regulatory element binding transcription factor 1 |
multiple interactions |
ISO |
Triolein inhibits the reaction [SCD1 gene mutant form inhibits the reaction [Fructose results in increased expression of SREBF1 mRNA]]; Triolein inhibits the reaction [SCD1 gene mutant form inhibits the reaction [Fructose results in increased expression of SREBF1 protein]] |
CTD |
PMID:15066988 |
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NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650
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