Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 61928
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Hif1a
Name: hypoxia inducible factor 1 subunit alpha
Acc ID: CHEBI:38725
Term: mevinphos
Definition: An organophosphate insecticide that has formula C7H13O6P.
Chemical ID: MESH:D008799
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Hif1amultiple interactionsEXP 6480464CTDHIF1A protein affects the reaction [Mevinphos results in increased expression of HMOX1 protein] HIF1A protein affects the reaction [Mevinphos results in increased expression of NOS1 protein] HIF1A protein affects the reaction [Mevinphos results in increased expression of PRKG1 protein] Mevinphos promotes the reaction [HIF1A protein binds to ARNT protein] Mevinphos promotes the reaction [HIF1A protein binds to SUMO1 protein] Mevinphos results in increased expression of and affects the localization of HIF1A protein Mevinphos results in increased expression of and results in increased activity of HIF1A protein SUMO1 protein affects the reaction [Mevinphos results in increased expression of and results in increased activity of HIF1A protein] UBE2I protein affects the reaction [Mevinphos results in increased expression of and results in increased activity of HIF1A protein]

PMID:19333137 PMID:21390240
Go Back to source page   Continue to Ontology report