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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.
Term:hexadecenoic acid
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Accession:CHEBI:24548 term browser browse the term
Definition:A C16 straight-chain monounsaturated fatty acid having one C=C double bond.
Synonyms:related_synonym: 16:1;   C16:1;   FA 16:1;   Formula=C16H30O2;   Hexadecensaeure;   Hexadecensaeuren;   acide hexadecenoique;   acides hexadecenoiques;   acido hexadecenoico;   acidos hexadecenoicos;   hexadecenoic acid 16:1
 xref: PMID:17439666
 cyclic_relationship: is_conjugate_acid_of CHEBI:78095


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palmitoleic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Abca1 ATP binding cassette subfamily A member 1 increases degradation
increases phosphorylation
multiple interactions		 ISO palmitoleic acid results in increased degradation of ABCA1 protein
palmitoleic acid results in increased phosphorylation of ABCA1 protein
palmitoleic acid inhibits the reaction [APOA1 protein affects the reaction [ABCA1 protein results in increased transport of Cholesterol]]; palmitoleic acid inhibits the reaction [APOA1 protein affects the reaction [ABCA1 protein results in increased transport of Phospholipids]]		 CTD PMID:16118212 NCBI chr 5:72,473,676...72,596,563
Ensembl chr 5:67,681,297...67,801,170 		JBrowse link
G Apoa1 apolipoprotein A1 multiple interactions ISO palmitoleic acid inhibits the reaction [APOA1 protein affects the reaction [ABCA1 protein results in increased transport of Cholesterol]]; palmitoleic acid inhibits the reaction [APOA1 protein affects the reaction [ABCA1 protein results in increased transport of Phospholipids]] CTD PMID:16118212 NCBI chr 8:55,423,945...55,425,729
Ensembl chr 8:46,527,144...46,529,035 		JBrowse link
G App amyloid beta precursor protein multiple interactions ISO [APP protein mutant form co-treated with PSEN1 protein mutant form] results in decreased abundance of palmitoleic acid; PF-06840003 inhibits the reaction [[APP protein mutant form co-treated with PSEN1 protein mutant form] results in decreased abundance of palmitoleic acid] CTD PMID:39172838 NCBI chr11:37,506,207...37,724,351
Ensembl chr11:24,019,778...24,236,561 		JBrowse link
G Il6 interleukin 6 increases expression ISO palmitoleic acid results in increased expression of IL6 mRNA CTD PMID:30524225 NCBI chr 4:5,889,999...5,894,575
Ensembl chr 4:5,213,394...5,219,178 		JBrowse link
G Ins2 insulin 2 multiple interactions ISO [1-Methyl-3-isobutylxanthine co-treated with Dexamethasone co-treated with INS protein] results in increased abundance of palmitoleic acid analog CTD PMID:26820058 NCBI chr 1:207,272,738...207,421,998
Ensembl chr 1:197,843,281...197,864,775 		JBrowse link
G Pck1 phosphoenolpyruvate carboxykinase 1 multiple interactions ISO [Glucose deficiency co-treated with palmitoleic acid] results in increased expression of PCK1 mRNA CTD PMID:8536680 NCBI chr 3:182,348,572...182,354,521
Ensembl chr 3:161,930,256...161,936,191 		JBrowse link
G Pon1 paraoxonase 1 multiple interactions
decreases activity		 ISO palmitoleic acid inhibits the reaction [[Ascorbic Acid co-treated with Copper Sulfate] results in decreased activity of PON1 protein]; palmitoleic acid inhibits the reaction [PON1 protein results in increased hydrolysis of Paraoxon]
palmitoleic acid results in decreased activity of PON1 protein		 CTD PMID:12871208 PMID:15375178 NCBI chr 4:34,261,312...34,292,327
Ensembl chr 4:33,294,722...33,321,360 		JBrowse link
G Psen1 presenilin 1 multiple interactions ISO [APP protein mutant form co-treated with PSEN1 protein mutant form] results in decreased abundance of palmitoleic acid; PF-06840003 inhibits the reaction [[APP protein mutant form co-treated with PSEN1 protein mutant form] results in decreased abundance of palmitoleic acid] CTD PMID:39172838 NCBI chr 6:109,054,160...109,106,191
Ensembl chr 6:103,323,120...103,371,650 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19909
    chemical entity 19907
      atom 19907
        nonmetal atom 19831
          carbon atom 19781
            organic molecular entity 19781
              olefinic compound 16983
                olefinic fatty acid 816
                  hexadecenoic acid 8
                    (14Z)-hexadecenoic acid 0
                    (3E)-3-hexadecenoic acid 0
                    (4Z)-hexadecenoic acid + 0
                    (E)-hexadec-2-enoic acid + 0
                    (Z)-hexadec-11-enoic acid + 0
                    (Z)-hexadec-7-enoic acid + 0
                    N-hexadecenoylsphingosine-1-phosphocholine + 0
                    O-hexadecenoyl-L-carnitine + 0
                    O-hexadecenoylcarnitine + 0
                    hexadec-9-enoic acid + 8
                    monoacylglycerol 16:1 + 0
                    sapienic acid + 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19909
    subatomic particle 19907
      composite particle 19907
        hadron 19907
          baryon 19907
            nucleon 19907
              atomic nucleus 19907
                atom 19907
                  main group element atom 19846
                    p-block element atom 19846
                      carbon group element atom 19784
                        carbon atom 19781
                          organic molecular entity 19781
                            heteroorganic entity 19540
                              organochalcogen compound 19301
                                organooxygen compound 19216
                                  carbon oxoacid 18696
                                    carboxylic acid 18693
                                      monocarboxylic acid 18028
                                        fatty acid 16860
                                          unsaturated fatty acid 1693
                                            monounsaturated fatty acid 624
                                              hexadecenoic acid 8
                                                (14Z)-hexadecenoic acid 0
                                                (3E)-3-hexadecenoic acid 0
                                                (4Z)-hexadecenoic acid + 0
                                                (E)-hexadec-2-enoic acid + 0
                                                (Z)-hexadec-11-enoic acid + 0
                                                (Z)-hexadec-7-enoic acid + 0
                                                N-hexadecenoylsphingosine-1-phosphocholine + 0
                                                O-hexadecenoyl-L-carnitine + 0
                                                O-hexadecenoylcarnitine + 0
                                                hexadec-9-enoic acid + 8
                                                monoacylglycerol 16:1 + 0
                                                sapienic acid + 0
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