Hoxa11 (homeobox A11) - Rat Genome Database

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Gene: Hoxa11 (homeobox A11) Rattus norvegicus
Analyze
Symbol: Hoxa11
Name: homeobox A11
RGD ID: 1564605
Description: Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in prostate gland development; response to estrogen; and response to testosterone. Predicted to be located in nucleoplasm. Predicted to be part of protein-DNA complex and transcription regulator complex. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in radioulnar synostosis. Orthologous to human HOXA11 (homeobox A11); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: homeo box A10; homeobox protein A10; homeobox protein Hox-A11; homeobox protein Hox-A11-like; Hoxa10; LOC100909443; LOC368057; LOC500127; MGC188427; RGD1564605; RGD1566402; similar to homeobox protein
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2481,342,527 - 81,346,189 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl481,342,528 - 81,346,232 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx486,564,339 - 86,567,995 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0482,339,730 - 82,343,386 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0480,766,832 - 80,770,490 (-)NCBIRnor_WKY
Rnor_6.0482,296,888 - 82,301,419 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl482,298,152 - 82,300,503 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl482,211,366 - 82,215,022 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04146,963,720 - 146,967,382 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4480,542,417 - 80,546,079NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera476,233,120 - 76,236,782 (-)NCBICelera
Cytogenetic Map4q24NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Posterior Hox gene expression and differential androgen regulation in the developing and adult rat prostate lobes. Huang L, etal., Endocrinology. 2007 Mar;148(3):1235-45. Epub 2006 Nov 30.
3. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
4. GOA pipeline RGD automated data pipeline
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. Abnormalities of vertebral formation and Hox expression in congenital kyphoscoliotic rats. Seki T, etal., Mol Cell Biochem. 2008 May;312(1-2):193-9. doi: 10.1007/s11010-008-9734-4. Epub 2008 Mar 9.
8. Amegakaryocytic thrombocytopenia and radio-ulnar synostosis are associated with HOXA11 mutation. Thompson AA and Nguyen LT, Nat Genet. 2000 Dec;26(4):397-8.
9. Developmental exposure to Bisphenol a impairs the uterine response to ovarian steroids in the adult. Varayoud J, etal., Endocrinology. 2008 Nov;149(11):5848-60. doi: 10.1210/en.2008-0651. Epub 2008 Jul 24.
Additional References at PubMed
PMID:7596412   PMID:7702549   PMID:7789268   PMID:9343407   PMID:11493536   PMID:11900456   PMID:12050119   PMID:12477932   PMID:12869760   PMID:14668414   PMID:15057822   PMID:15632090  
PMID:17785448   PMID:18249394   PMID:18701816   PMID:20978074   PMID:22916278   PMID:23760953  


Genomics

Comparative Map Data
Hoxa11
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2481,342,527 - 81,346,189 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl481,342,528 - 81,346,232 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx486,564,339 - 86,567,995 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0482,339,730 - 82,343,386 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0480,766,832 - 80,770,490 (-)NCBIRnor_WKY
Rnor_6.0482,296,888 - 82,301,419 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl482,298,152 - 82,300,503 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.0 Ensembl482,211,366 - 82,215,022 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04146,963,720 - 146,967,382 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4480,542,417 - 80,546,079NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera476,233,120 - 76,236,782 (-)NCBICelera
Cytogenetic Map4q24NCBI
HOXA11
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38727,181,157 - 27,185,232 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl727,181,157 - 27,185,232 (-)EnsemblGRCh38hg38GRCh38
GRCh37727,220,776 - 27,224,851 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36727,187,301 - 27,191,360 (-)NCBINCBI36Build 36hg18NCBI36
Build 34726,994,368 - 26,998,070NCBI
Celera727,209,715 - 27,213,774 (-)NCBICelera
Cytogenetic Map7p15.2NCBI
HuRef727,101,338 - 27,105,401 (-)NCBIHuRef
CHM1_1727,220,497 - 27,224,560 (-)NCBICHM1_1
T2T-CHM13v2.0727,317,166 - 27,321,240 (-)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2727,271,961 - 27,276,020 (-)NCBI
Hoxa11
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39652,219,085 - 52,222,790 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl652,219,086 - 52,222,790 (-)EnsemblGRCm39 Ensembl
GRCm38652,242,105 - 52,245,810 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl652,242,106 - 52,245,810 (-)EnsemblGRCm38mm10GRCm38
MGSCv37652,192,105 - 52,195,766 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36652,171,689 - 52,175,350 (-)NCBIMGSCv36mm8
Celera652,763,744 - 52,767,403 (-)NCBICelera
Cytogenetic Map6B3NCBI
cM Map625.4NCBI
Hoxa11
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495541028,877,055 - 28,879,465 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495541028,875,780 - 28,879,643 (-)NCBIChiLan1.0ChiLan1.0
HOXA11
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1727,426,602 - 27,429,092 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl727,424,759 - 27,429,103 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0727,826,003 - 27,829,757 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
HOXA11
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11440,355,907 - 40,360,120 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1440,357,478 - 40,359,919 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1439,786,761 - 39,790,944 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01440,294,564 - 40,298,764 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1440,295,087 - 40,299,055 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11440,408,521 - 40,412,708 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01440,093,599 - 40,097,769 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01440,452,219 - 40,456,401 (-)NCBIUU_Cfam_GSD_1.0
Hoxa11
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511884,597,557 - 84,601,354 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049364783,809,288 - 3,813,014 (-)EnsemblSpeTri2.0
SpeTri2.0NW_0049364783,809,288 - 3,813,014 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HOXA11
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1845,388,375 - 45,391,953 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11845,388,523 - 45,392,190 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21850,021,709 - 50,025,376 (+)NCBISscrofa10.2Sscrofa10.2susScr3
HOXA11
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12131,180,232 - 31,187,709 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2131,183,682 - 31,186,010 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604273,546,525 - 73,553,107 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Hoxa11
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247393,418,723 - 3,423,950 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247393,420,501 - 3,424,151 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Hoxa11
4 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:1182
Count of miRNA genes:291
Interacting mature miRNAs:371
Transcripts:ENSRNOT00000010256, ENSRNOT00000071568
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
2303168Bp330Blood pressure QTL 3304.250.017arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)45214602146446691Rat
631261Tcas3Tongue tumor susceptibility QTL 36.88tongue integrity trait (VT:0010553)number of squamous cell tumors of the tongue with diameter greater than 3 mm (CMO:0001950)41081417091360527Rat
2316958Gluco58Glucose level QTL 5810blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)411320076180699135Rat
12798520Anxrr55Anxiety related response QTL 554.450.01locomotor behavior trait (VT:0001392)number of rearing movements with lid-pushing in an experimental apparatus (CMO:0002715)432583980114627242Rat
8552782Vie1Viral induced encephalitis QTL 126.4brain integrity trait (VT:0010579)encephalitis incidence/prevalence measurement (CMO:0002361)43443048482490359Rat
8552801Bw143Body weight QTL 1437.3body mass (VT:0001259)change in body weight to body weight ratio (CMO:0002216)43443048482490359Rat
8552809Vie5Viral induced encephalitis QTL 525.3brain integrity trait (VT:0010579)encephalitis incidence/prevalence measurement (CMO:0002361)43443048482490359Rat
8655961Kidm43Kidney mass QTL 4318kidney mass (VT:0002707)both kidneys wet weight (CMO:0000085)436303261103194984Rat
1358352Srcrt3Stress Responsive Cort QTL 32.29blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)438465774146803430Rat
1300139Hrtrt6Heart rate QTL 62.85heart pumping trait (VT:2000009)heart rate (CMO:0000002)439524264116179656Rat
61445Strs3Sensitivity to stroke QTL 33cerebrum integrity trait (VT:0010549)post-insult time to onset of cerebrovascular lesion (CMO:0002343)44043338885433388Rat
8694439Bw168Body weight QTL 1689.570.001retroperitoneal fat pad mass (VT:0010430)retroperitoneal fat pad weight to body weight ratio (CMO:0000635)44043341485433414Rat
6893678Bw108Body weight QTL 1082.60.006body mass (VT:0001259)body weight (CMO:0000012)44345797688457976Rat
1576305Emca6Estrogen-induced mammary cancer QTL 65.8mammary gland integrity trait (VT:0010552)mammary tumor number (CMO:0000343)444463720155883716Rat
1354612Foco1Food consumption QTL 18.87eating behavior trait (VT:0001431)food intake rate (CMO:0000427)444463908148090542Rat
1354660Salc1Saline consumption QTL 111.26drinking behavior trait (VT:0001422)saline drink intake rate (CMO:0001627)444463908148090542Rat
2312567Glom19Glomerulus QTL 191.90.006kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)445456990146803430Rat
1298082Stresp4Stress response QTL 4blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)450119848146803430Rat
70200Alc18Alcohol consumption QTL 189.2drinking behavior trait (VT:0001422)ethanol intake volume to total fluid intake volume ratio (CMO:0001591)456647873149491524Rat
1641833Alc21Alcohol consumption QTL 218.60.0001drinking behavior trait (VT:0001422)ethanol drink intake rate (CMO:0001407)456698790126192555Rat
631546Bp86Blood pressure QTL 863.2arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)45711443291360801Rat
634311Sach7Saccharin preference QTL 7taste sensitivity trait (VT:0001986)saccharin intake volume to total fluid intake volume ratio (CMO:0001601)457114432102114432Rat
1358363Sradr3Stress Responsive Adrenal Weight QTL 36.19adrenal gland mass (VT:0010420)both adrenal glands wet weight (CMO:0000164)457486946102486946Rat
1558651Swd3Spike wave discharge measurement QTL 34.620.000024brain electrophysiology trait (VT:0010557)brain spike-and-wave discharge frequency (CMO:0001742)45843213392991462Rat
738009Sach4Saccharine consumption QTL 44.90.000016consumption behavior trait (VT:0002069)saccharin intake volume to total fluid intake volume ratio (CMO:0001601)459948935154902892Rat
738016Alc16Alcohol consumption QTL 163.60.00015consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)459948935154902892Rat
738031Alc14Alcohol consumption QTL 147.60.00003consumption behavior trait (VT:0002069)ethanol drink intake rate to body weight ratio (CMO:0001616)459948935154902892Rat
1578657Bss12Bone structure and strength QTL 128.9femur morphology trait (VT:0000559)femoral neck cross-sectional area (CMO:0001697)460220938105220938Rat
1578658Bss13Bone structure and strength QTL 138femur strength trait (VT:0010010)femoral neck polar moment of inertia (CMO:0001670)460220938105220938Rat
2300179Bmd50Bone mineral density QTL 505.90.0001femur mineral mass (VT:0010011)volumetric bone mineral density (CMO:0001553)460928534105928534Rat
1549843Bw53Body weight QTL 530.0001body mass (VT:0001259)body weight gain (CMO:0000420)461697658103194791Rat
1549839Bw52Body weight QTL 520.0001body mass (VT:0001259)body weight gain (CMO:0000420)461697658115089733Rat
61418Pia5Pristane induced arthritis QTL 54.5joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)462277855128289560Rat
6478743Anxrr40Anxiety related response QTL 400.83076defecation behavior trait (VT:0010462)defecation rate (CMO:0000998)462753847107753847Rat
6478772Anxrr49Anxiety related response QTL 490.15488defecation behavior trait (VT:0010462)defecation rate (CMO:0000998)462753847107753847Rat
6478684Anxrr30Anxiety related response QTL 300.00087defecation behavior trait (VT:0010462)defecation rate (CMO:0000998)462753847107753847Rat
631651Bp124Blood pressure QTL 1243arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)462879517107879517Rat
7394826Bw126Body weight QTL 1260.002body mass (VT:0001259)body weight gain (CMO:0000420)46293326987483707Rat
8552807Vie4Viral induced encephalitis QTL 47.3brain integrity trait (VT:0010579)encephalitis incidence/prevalence measurement (CMO:0002361)46293350882490359Rat
70192BpQTLcluster5Blood pressure QTL cluster 54.183arterial blood pressure trait (VT:2000000)diastolic blood pressure (CMO:0000005)462933508114921294Rat
70192BpQTLcluster5Blood pressure QTL cluster 54.183arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)462933508114921294Rat
70192BpQTLcluster5Blood pressure QTL cluster 54.183arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)462933508114921294Rat
70192BpQTLcluster5Blood pressure QTL cluster 54.183arterial blood pressure trait (VT:2000000)percent change in mean arterial blood pressure (CMO:0002035)462933508114921294Rat
70192BpQTLcluster5Blood pressure QTL cluster 54.183arterial blood pressure trait (VT:2000000)percent change in systolic blood pressure (CMO:0000747)462933508114921294Rat
70192BpQTLcluster5Blood pressure QTL cluster 54.183arterial blood pressure trait (VT:2000000)absolute change in pulse pressure (CMO:0001882)462933508114921294Rat
70192BpQTLcluster5Blood pressure QTL cluster 54.183arterial blood pressure trait (VT:2000000)absolute change in mean arterial blood pressure (CMO:0000533)462933508114921294Rat
631674Iddm14Insulin dependent diabetes mellitus QTL 14blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)464528739157573521Rat
2312569Pur19Proteinuria QTL 193.40.001urine total protein amount (VT:0000032)urine total protein excretion rate (CMO:0000756)46588210796130297Rat
61330Eau1Experimental allergic uveoretinitis QTL 10.0003uvea integrity trait (VT:0010551)experimental autoimmune uveitis score (CMO:0001504)470362013132642728Rat
634344Hcar7Hepatocarcinoma resistance QTL 77.8liver integrity trait (VT:0010547)liver tumorous lesion area to total liver area ratio (CMO:0001075)470808386115808386Rat
634344Hcar7Hepatocarcinoma resistance QTL 77.8liver integrity trait (VT:0010547)liver tumorous lesion number (CMO:0001068)470808386115808386Rat
631646Stl4Serum triglyceride level QTL 46.50.0001blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)473169846132642728Rat
724522Bp146Blood pressure QTL 1462.20.0021arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)473630210118630210Rat
2302051Pia28Pristane induced arthritis QTL 285.30.001blood autoantibody amount (VT:0003725)serum immunoglobulin G-type rheumatoid factor level relative to an arbitrary reference serum (CMO:0002112)473630210118630210Rat
70167Bw22Body weight QTL 223.1body mass (VT:0001259)body weight (CMO:0000012)476647384117676292Rat
1357342Bw40Body weight QTL 400.001body mass (VT:0001259)body weight (CMO:0000012)476647384117676292Rat
631662Hcar2Hepatocarcinoma resistance QTL 23.10.0003liver integrity trait (VT:0010547)volume of individual liver tumorous lesion (CMO:0001078)478878504123878504Rat
631556Bp135Blood pressure QTL 1350.017arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)478881294117676292Rat
2317586Eae25Experimental allergic encephalomyelitis QTL 259.300000190734863nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis severity score (CMO:0001419)47888281783007655Rat
2317586Eae25Experimental allergic encephalomyelitis QTL 259.300000190734863nervous system integrity trait (VT:0010566)percentage of study population developing experimental autoimmune encephalomyelitis during a period of time (CMO:0001047)47888281783007655Rat
2317586Eae25Experimental allergic encephalomyelitis QTL 259.300000190734863nervous system integrity trait (VT:0010566)post-insult time to onset of experimental autoimmune encephalomyelitis (CMO:0001422)47888281783007655Rat
2317586Eae25Experimental allergic encephalomyelitis QTL 259.300000190734863nervous system integrity trait (VT:0010566)experimental autoimmune encephalomyelitis duration (CMO:0001424)47888281783007655Rat
61364Iddm2Insulin dependent diabetes mellitus QTL 2blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)478885890102684881Rat
738015Pia9Pristane induced arthritis QTL 94.50.048joint integrity trait (VT:0010548)joint inflammation composite score (CMO:0000919)480694870125694870Rat
2306899Bp338Blood pressure QTL 3380.071arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)481006124120102625Rat
1641919Alc22Alcohol consumption QTL 220.0005drinking behavior trait (VT:0001422)ethanol drink intake rate (CMO:0001407)481192555126192555Rat

Markers in Region
U20371  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2481,343,516 - 81,343,709 (+)MAPPERmRatBN7.2
Rnor_6.0482,297,879 - 82,298,071NCBIRnor6.0
Rnor_6.0482,212,355 - 82,212,547NCBIRnor6.0
Rnor_5.04146,879,186 - 146,879,378UniSTSRnor5.0
Rnor_5.04146,964,710 - 146,964,902UniSTSRnor5.0
RGSC_v3.4480,543,407 - 80,543,599UniSTSRGSC3.4
Celera476,234,110 - 76,234,302UniSTS
Cytogenetic Map4q24UniSTS
D7S2774  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2481,332,478 - 81,332,819 (+)MAPPERmRatBN7.2
Rnor_6.0482,286,842 - 82,287,182NCBIRnor6.0
Rnor_6.0482,201,047 - 82,201,387NCBIRnor6.0
Rnor_5.04146,867,878 - 146,868,218UniSTSRnor5.0
Rnor_5.04146,953,673 - 146,954,013UniSTSRnor5.0
RGSC_v3.4480,532,370 - 80,532,710UniSTSRGSC3.4
Celera476,223,112 - 76,223,452UniSTS
Cytogenetic Map4q24UniSTS
AA893141  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2481,332,690 - 81,332,897 (+)MAPPERmRatBN7.2
Rnor_6.0482,287,054 - 82,287,260NCBIRnor6.0
Rnor_6.0482,201,259 - 82,201,465NCBIRnor6.0
Rnor_5.04146,953,885 - 146,954,091UniSTSRnor5.0
Rnor_5.04146,868,090 - 146,868,296UniSTSRnor5.0
RGSC_v3.4480,532,582 - 80,532,788UniSTSRGSC3.4
Celera476,223,324 - 76,223,530UniSTS
RH 3.4 Map4513.31UniSTS
Cytogenetic Map4q24UniSTS
UniSTS:498386  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2481,343,486 - 81,343,571 (+)MAPPERmRatBN7.2
Rnor_6.0482,297,849 - 82,297,933NCBIRnor6.0
Rnor_6.0482,212,325 - 82,212,409NCBIRnor6.0
Rnor_5.04146,879,156 - 146,879,240UniSTSRnor5.0
Rnor_5.04146,964,680 - 146,964,764UniSTSRnor5.0
RGSC_v3.4480,543,377 - 80,543,461UniSTSRGSC3.4
Celera476,234,080 - 76,234,164UniSTS
Cytogenetic Map4q24UniSTS
UniSTS:474751  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2481,342,863 - 81,343,174 (+)MAPPERmRatBN7.2
Rnor_6.0482,297,226 - 82,297,536NCBIRnor6.0
Rnor_6.0482,211,702 - 82,212,012NCBIRnor6.0
Rnor_5.04146,878,533 - 146,878,843UniSTSRnor5.0
Rnor_5.04146,964,057 - 146,964,367UniSTSRnor5.0
RGSC_v3.4480,542,754 - 80,543,064UniSTSRGSC3.4
Celera476,233,457 - 76,233,767UniSTS
Cytogenetic Map4q24UniSTS
REN100703  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2481,345,248 - 81,345,474 (+)MAPPERmRatBN7.2
Rnor_6.0482,299,611 - 82,299,836NCBIRnor6.0
Rnor_6.0482,214,087 - 82,214,312NCBIRnor6.0
Rnor_5.04146,880,918 - 146,881,143UniSTSRnor5.0
Rnor_5.04146,966,442 - 146,966,667UniSTSRnor5.0
RGSC_v3.4480,545,139 - 80,545,364UniSTSRGSC3.4
Celera476,235,842 - 76,236,067UniSTS
Cytogenetic Map4q24UniSTS
REN100704  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2481,345,451 - 81,345,682 (+)MAPPERmRatBN7.2
Rnor_6.0482,299,814 - 82,300,044NCBIRnor6.0
Rnor_6.0482,214,290 - 82,214,520NCBIRnor6.0
Rnor_5.04146,881,121 - 146,881,351UniSTSRnor5.0
Rnor_5.04146,966,645 - 146,966,875UniSTSRnor5.0
RGSC_v3.4480,545,342 - 80,545,572UniSTSRGSC3.4
Celera476,236,045 - 76,236,275UniSTS
Cytogenetic Map4q24UniSTS
REN100706  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2481,345,887 - 81,346,147 (+)MAPPERmRatBN7.2
Rnor_6.0482,300,250 - 82,300,509NCBIRnor6.0
Rnor_6.0482,214,726 - 82,214,985NCBIRnor6.0
Rnor_5.04146,881,557 - 146,881,816UniSTSRnor5.0
Rnor_5.04146,967,081 - 146,967,340UniSTSRnor5.0
RGSC_v3.4480,545,778 - 80,546,037UniSTSRGSC3.4
Celera476,236,481 - 76,236,740UniSTS
Cytogenetic Map4q24UniSTS
ECD05496  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2481,345,709 - 81,346,446 (+)MAPPERmRatBN7.2
Rnor_6.0482,300,072 - 82,300,808NCBIRnor6.0
Rnor_6.0482,214,548 - 82,215,284NCBIRnor6.0
Rnor_5.04146,881,379 - 146,882,115UniSTSRnor5.0
Rnor_5.04146,966,903 - 146,967,639UniSTSRnor5.0
RGSC_v3.4480,545,600 - 80,546,336UniSTSRGSC3.4
Celera476,236,303 - 76,237,039UniSTS
Cytogenetic Map4q24UniSTS
Hoxa11  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2481,345,990 - 81,346,064 (+)MAPPERmRatBN7.2
Rnor_6.0482,214,829 - 82,214,902NCBIRnor6.0
Rnor_6.0482,300,353 - 82,300,426NCBIRnor6.0
Rnor_5.04146,967,184 - 146,967,257UniSTSRnor5.0
Rnor_5.04146,881,660 - 146,881,733UniSTSRnor5.0
Celera476,236,584 - 76,236,657UniSTS
Cytogenetic Map4q24UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system endocrine system exocrine system hepatobiliary system integumental system musculoskeletal system renal system reproductive system respiratory system appendage
High
Medium 20 12
Low 2 6 8 15 14 6
Below cutoff 2 2 2 1 2 3 1 1

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000010256   ⟹   ENSRNOP00000010256
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl481,342,528 - 81,346,232 (-)Ensembl
Rnor_6.0 Ensembl482,211,366 - 82,215,022 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000071568   ⟹   ENSRNOP00000066085
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl482,298,152 - 82,300,503 (-)Ensembl
RefSeq Acc Id: NM_001129878   ⟹   NP_001123350
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2481,342,527 - 81,346,189 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001123350 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAI66717 (Get FASTA)   NCBI Sequence Viewer  
  AAP31870 (Get FASTA)   NCBI Sequence Viewer  
  EDL88153 (Get FASTA)   NCBI Sequence Viewer  
  EDL88154 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: ENSRNOP00000010256   ⟸   ENSRNOT00000010256
RefSeq Acc Id: ENSRNOP00000066085   ⟸   ENSRNOT00000071568
RefSeq Acc Id: NP_001123350   ⟸   NM_001129878
- UniProtKB: G3V6Z0 (UniProtKB/TrEMBL)
- Sequence:
Protein Domains
Homeobox

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-G3V6Z0-F1-model_v2 AlphaFold G3V6Z0 1-313 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13693059
Promoter ID:EPDNEW_R3580
Type:initiation region
Name:Hoxa11_1
Description:homeobox A11
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0482,300,586 - 82,300,646EPDNEW
RGD ID:13693061
Promoter ID:EPDNEW_R3581
Type:single initiation site
Name:AABR07060585_1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0482,300,786 - 82,300,846EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1564605 AgrOrtholog
BioCyc Gene G2FUF-44811 BioCyc
Ensembl Genes ENSRNOG00000053884 Ensembl
  ENSRNOG00000059870 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000010256 ENTREZGENE
  ENSRNOP00000010256.3 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000010256 ENTREZGENE
  ENSRNOT00000010256.6 UniProtKB/TrEMBL
InterPro DUF3528 UniProtKB/TrEMBL
  Homeobox UniProtKB/TrEMBL
  Homeobox_CS UniProtKB/TrEMBL
  Homeobox_eu UniProtKB/TrEMBL
  Homeodomain-like UniProtKB/TrEMBL
KEGG Report rno:103692131 UniProtKB/TrEMBL
NCBI Gene 103692131 ENTREZGENE
Pfam DUF3528 UniProtKB/TrEMBL
  Homeobox UniProtKB/TrEMBL
PhenoGen Hoxa11 PhenoGen
PRINTS HOMEOBOX UniProtKB/TrEMBL
PROSITE HOMEOBOX_1 UniProtKB/TrEMBL
  HOMEOBOX_2 UniProtKB/TrEMBL
SMART HOX UniProtKB/TrEMBL
Superfamily-SCOP Homeodomain_like UniProtKB/TrEMBL
UniProt G3V6Z0 ENTREZGENE, UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-07-27 Hoxa11  homeobox A11  LOC100909443  homeobox protein Hox-A11-like  Data Merged 737654 PROVISIONAL
2013-05-24 Hoxa11  homeobox A11  RGD1566402  similar to homeobox protein  Data Merged 1643240 APPROVED
2012-07-17 Hoxa11  homeobox A11  Hoxa10  homeo box A10  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2012-07-05 LOC100909443  homeobox protein Hox-A11-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2012-07-05 LOC100911743  homeobox protein Hox-A11-like      Symbol and Name status set to provisional 70820 PROVISIONAL
2008-04-30 RGD1566402  similar to homeobox protein   RGD1566402_predicted  similar to homeobox protein (predicted)  'predicted' is removed 2292626 APPROVED
2008-03-06 Hoxa10  homeo box A10  RGD1564605_predicted  similar to Homeobox protein A10 (predicted)  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-03-07 RGD1564605_predicted  similar to Homeobox protein A10 (predicted)  LOC368057  similar to Homeobox protein A10  Symbol and Name status set to approved 1299863 APPROVED
2006-03-07 RGD1566402_predicted  similar to homeobox protein (predicted)  LOC500127  similar to homeobox protein  Symbol and Name status set to approved 1299863 APPROVED
2006-02-09 LOC368057  similar to Homeobox protein A10      Symbol and Name status set to provisional 70820 PROVISIONAL
2006-02-09 LOC500127  similar to homeobox protein      Symbol and Name status set to provisional 70820 PROVISIONAL