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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:hydroxy monounsaturated fatty acid
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Accession:CHEBI:131869 term browser browse the term
Definition:Any monounsaturated fatty acid carrying one or more hydroxy substituents.
Synonyms:related_synonym: hydroxy MUFA;   hydroxy monounsaturated fatty acids


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castor oil term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pafah1b1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 increases expression
multiple interactions
EXP Castor Oil results in increased expression of PAFAH1B1 protein
isosorbide-5-mononitrate inhibits the reaction [Castor Oil results in increased expression of PAFAH1B1 protein]
CTD PMID:1354728 PMID:2743081 PMID:8738301 NCBI chr10:61,456,144...61,577,412
Ensembl chr10:61,456,145...61,577,412
JBrowse link
ricinoleic acid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cnr1 cannabinoid receptor 1 affects binding ISO ricinoleic acid analog binds to CNR1 protein CTD PMID:16406364 NCBI chr 5:49,307,584...49,333,064
Ensembl chr 5:49,311,030...49,333,056
JBrowse link
G Cnr2 cannabinoid receptor 2 multiple interactions ISO ricinoleic acid analog binds to and affects the activity of CNR2 protein CTD PMID:16406364 NCBI chr 5:154,242,010...154,268,126
Ensembl chr 5:154,260,062...154,268,126
JBrowse link
G Il4 interleukin 4 multiple interactions ISO ricinoleic acid inhibits the reaction [IL4 protein results in increased expression of VCAM1 protein] CTD PMID:7544037 NCBI chr10:38,963,979...38,969,531
Ensembl chr10:38,963,979...38,969,531
JBrowse link
G Ptgds prostaglandin D2 synthase affects binding ISO ricinoleic acid binds to PTGDS protein CTD PMID:26456343 NCBI chr 3:2,686,125...2,689,059
Ensembl chr 3:2,686,123...2,689,084
JBrowse link
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 multiple interactions ISO ricinoleic acid analog binds to and affects the activity of TRPV1 protein CTD PMID:16406364 NCBI chr10:59,799,123...59,824,208
Ensembl chr10:59,799,123...59,824,679
JBrowse link
G Vcam1 vascular cell adhesion molecule 1 multiple interactions ISO ricinoleic acid inhibits the reaction [IL4 protein results in increased expression of VCAM1 protein] CTD PMID:7544037 NCBI chr 2:219,071,193...219,090,931
Ensembl chr 2:219,071,193...219,097,619
JBrowse link
royal jelly term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcl2 BCL2, apoptosis regulator multiple interactions ISO royal jelly inhibits the reaction [Nicotine results in decreased expression of BCL2 mRNA] CTD PMID:30896085 NCBI chr13:26,605,426...26,769,374
Ensembl chr13:26,605,426...26,769,374
JBrowse link
G Casp3 caspase 3 multiple interactions ISO royal jelly inhibits the reaction [Nicotine results in increased expression of CASP3 mRNA] CTD PMID:30896085 NCBI chr16:48,845,011...48,863,249
Ensembl chr16:48,845,012...48,863,204
JBrowse link
G Cat catalase multiple interactions EXP
ISO
royal jelly inhibits the reaction [Cisplatin results in decreased activity of CAT protein]
royal jelly inhibits the reaction [Nicotine results in decreased activity of CAT protein]
CTD PMID:20369241 PMID:30896085 NCBI chr 3:93,379,872...93,412,058
Ensembl chr 3:93,379,874...93,412,058
JBrowse link
G Esr1 estrogen receptor 1 multiple interactions
increases activity
affects binding
ISO Estradiol inhibits the reaction [royal jelly binds to ESR1 protein]; royal jelly binds to and results in increased activity of ESR1 protein; royal jelly inhibits the reaction [Estradiol binds to ESR1 protein]
royal jelly results in increased activity of ESR1 protein
CTD PMID:15946813 PMID:17287592 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Esr2 estrogen receptor 2 multiple interactions
affects binding
ISO Estradiol inhibits the reaction [royal jelly binds to ESR2 protein]; royal jelly binds to and results in increased activity of ESR2 protein; royal jelly inhibits the reaction [Estradiol binds to ESR2 protein] CTD PMID:15946813 PMID:17287592 NCBI chr 6:99,163,953...99,214,711
Ensembl chr 6:99,164,357...99,214,251
JBrowse link
G Pcna proliferating cell nuclear antigen multiple interactions ISO royal jelly inhibits the reaction [Nicotine results in decreased expression of PCNA protein] CTD PMID:30896085 NCBI chr 3:124,880,698...124,884,570
Ensembl chr 3:124,880,698...124,884,570
JBrowse link
G Tff1 trefoil factor 1 increases expression ISO royal jelly results in increased expression of TFF1 mRNA CTD PMID:15946813 NCBI chr20:9,892,124...9,895,984
Ensembl chr20:9,892,124...9,895,984
JBrowse link
G Tp53 tumor protein p53 multiple interactions ISO royal jelly inhibits the reaction [Nicotine results in increased expression of TRP53 mRNA] CTD PMID:30896085 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Vegfa vascular endothelial growth factor A increases expression ISO
EXP
royal jelly results in increased expression of VEGFA mRNA CTD PMID:15946813 PMID:17287592 NCBI chr 9:17,340,341...17,355,681
Ensembl chr 9:17,340,341...17,355,681
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  CHEBI ontology 19773
    chemical entity 19773
      atom 19771
        nonmetal atom 19654
          carbon atom 19573
            organic molecular entity 19573
              lipid 17488
                fatty acid 16006
                  hydroxy fatty acid 191
                    hydroxy monounsaturated fatty acid 16
                      (12E)-9-hydroxy-10-oxo-12-octadecenoic acid 0
                      (2E)-11-hydroxy-2-dodecenoic acid 0
                      (2E)-11-hydroxyundec-2-enoic acid + 0
                      (2E)-12-hydroxydodec-2-enoic acid + 0
                      (2E)-13-hydroxytridec-2-enoic acid + 0
                      (2E)-14-hydroxytetradec-2-enoic acid + 0
                      (2E)-15-hydroxypentadec-2-enoic acid + 0
                      (2E)-16-hydroxyhexadec-2-enoic acid + 0
                      (2E)-17-hydroxyheptadec-2-enoic acid + 0
                      (2E)-18-hydroxyoctadec-2-enoic acid + 0
                      (2E)-19-hydroxynonadec-2-enoic acid + 0
                      (2E)-20-hydroxyicos-2-enoic acid + 0
                      (2E)-21-hydroxyhenicos-2-enoic acid + 0
                      (2E)-7-hydroxyhept-2-enoic acid + 0
                      (2E)-9-hydroxynon-2-enoic acid + 0
                      (2E,10R)-10-hydroxyundec-2-enoic acid + 0
                      (2E,11R)-11-hydroxydodec-2-enoic acid + 0
                      (2E,12R)-12-hydroxytridec-2-enoic acid + 0
                      (2E,13R)-13-hydroxytetradec-2-enoic acid + 0
                      (2E,14R)-14-hydroxypentadec-2-enoic acid + 0
                      (2E,15R)-15-hydroxyhexadec-2-enoic acid + 0
                      (2E,16R)-16-hydroxyheptadec-2-enoic acid + 0
                      (2E,17R)-17-hydroxyoctadec-2-enoic acid + 0
                      (2E,18R)-18-hydroxynonadec-2-enoic acid + 0
                      (2E,19R)-19-hydroxyicos-2-enoic acid + 0
                      (2E,20R)-20-hydroxyhenicos-2-enoic acid + 0
                      (2E,6R)-6-hydroxyhept-2-enoic acid + 0
                      (2E,7R)-7-hydroxyoct-2-enoic acid + 0
                      (2E,8R)-8-hydroxynon-2-enoic acid + 0
                      (2E,9R)-9-hydroxydec-2-enoic acid + 0
                      (4R,6Z)-4-hydroxydodec-6-enoic acid 0
                      (6E,8R,10Z)-8-hydroxy-3-oxohexadeca-6,10-dienoic acid 0
                      (7Z)-14-hydroxy-10,13-dioxoheptadec-7-enoic acid + 0
                      (9E)-12-hydroxyoctadec-9-enoic acid 0
                      (9Z)-12-hydroxyoctadec-9-enoic acid + 7
                      (9Z)-17-hydroxyoctadec-9-enoic acid + 0
                      (9Z,12R)-12,18-dihydroxyoctadecenoic acid 0
                      (E)-10-hydroxydec-2-enoic acid + 9
                      18-hydroxyoleic acid + 0
                      2-hydroxydodec-2-enoic acid 0
                      2-hydroxyerucic acid 0
                      2-hydroxygondoic acid 0
                      2-hydroxynervonic acid 0
                      2-hydroxyoleic acid 0
                      2-hydroxypalmitoleic acid 0
                      6-hydroxyhex-3-enoic acid + 0
                      9-hydroxyundec-10-enoic acid 0
                      TriHOME + 0
                      ambrettolic acid 0
                      ricinelaidic acid 0
                      tianshic acid 0
Path 2
Term Annotations click to browse term
  CHEBI ontology 19773
    subatomic particle 19771
      composite particle 19771
        hadron 19771
          baryon 19771
            nucleon 19771
              atomic nucleus 19771
                atom 19771
                  main group element atom 19665
                    p-block element atom 19665
                      carbon group element atom 19583
                        carbon atom 19573
                          organic molecular entity 19573
                            organic group 18603
                              organic divalent group 18594
                                organodiyl group 18594
                                  carbonyl group 18507
                                    carbonyl compound 18507
                                      carboxylic acid 18159
                                        monocarboxylic acid 17527
                                          fatty acid 16006
                                            unsaturated fatty acid 947
                                              monounsaturated fatty acid 447
                                                hydroxy monounsaturated fatty acid 16
                                                  (12E)-9-hydroxy-10-oxo-12-octadecenoic acid 0
                                                  (2E)-11-hydroxy-2-dodecenoic acid 0
                                                  (2E)-11-hydroxyundec-2-enoic acid + 0
                                                  (2E)-12-hydroxydodec-2-enoic acid + 0
                                                  (2E)-13-hydroxytridec-2-enoic acid + 0
                                                  (2E)-14-hydroxytetradec-2-enoic acid + 0
                                                  (2E)-15-hydroxypentadec-2-enoic acid + 0
                                                  (2E)-16-hydroxyhexadec-2-enoic acid + 0
                                                  (2E)-17-hydroxyheptadec-2-enoic acid + 0
                                                  (2E)-18-hydroxyoctadec-2-enoic acid + 0
                                                  (2E)-19-hydroxynonadec-2-enoic acid + 0
                                                  (2E)-20-hydroxyicos-2-enoic acid + 0
                                                  (2E)-21-hydroxyhenicos-2-enoic acid + 0
                                                  (2E)-7-hydroxyhept-2-enoic acid + 0
                                                  (2E)-9-hydroxynon-2-enoic acid + 0
                                                  (2E,10R)-10-hydroxyundec-2-enoic acid + 0
                                                  (2E,11R)-11-hydroxydodec-2-enoic acid + 0
                                                  (2E,12R)-12-hydroxytridec-2-enoic acid + 0
                                                  (2E,13R)-13-hydroxytetradec-2-enoic acid + 0
                                                  (2E,14R)-14-hydroxypentadec-2-enoic acid + 0
                                                  (2E,15R)-15-hydroxyhexadec-2-enoic acid + 0
                                                  (2E,16R)-16-hydroxyheptadec-2-enoic acid + 0
                                                  (2E,17R)-17-hydroxyoctadec-2-enoic acid + 0
                                                  (2E,18R)-18-hydroxynonadec-2-enoic acid + 0
                                                  (2E,19R)-19-hydroxyicos-2-enoic acid + 0
                                                  (2E,20R)-20-hydroxyhenicos-2-enoic acid + 0
                                                  (2E,6R)-6-hydroxyhept-2-enoic acid + 0
                                                  (2E,7R)-7-hydroxyoct-2-enoic acid + 0
                                                  (2E,8R)-8-hydroxynon-2-enoic acid + 0
                                                  (2E,9R)-9-hydroxydec-2-enoic acid + 0
                                                  (4R,6Z)-4-hydroxydodec-6-enoic acid 0
                                                  (6E,8R,10Z)-8-hydroxy-3-oxohexadeca-6,10-dienoic acid 0
                                                  (7Z)-14-hydroxy-10,13-dioxoheptadec-7-enoic acid + 0
                                                  (9E)-12-hydroxyoctadec-9-enoic acid 0
                                                  (9Z)-12-hydroxyoctadec-9-enoic acid + 7
                                                  (9Z)-17-hydroxyoctadec-9-enoic acid + 0
                                                  (9Z,12R)-12,18-dihydroxyoctadecenoic acid 0
                                                  (E)-10-hydroxydec-2-enoic acid + 9
                                                  18-hydroxyoleic acid + 0
                                                  2-hydroxydodec-2-enoic acid 0
                                                  2-hydroxyerucic acid 0
                                                  2-hydroxygondoic acid 0
                                                  2-hydroxynervonic acid 0
                                                  2-hydroxyoleic acid 0
                                                  2-hydroxypalmitoleic acid 0
                                                  6-hydroxyhex-3-enoic acid + 0
                                                  9-hydroxyundec-10-enoic acid 0
                                                  TriHOME + 0
                                                  ambrettolic acid 0
                                                  ricinelaidic acid 0
                                                  tianshic acid 0
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