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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 621314
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Hspd1
Name: heat shock protein family D (Hsp60) member 1
Acc ID: CHEBI:38725
Term: mevinphos
Definition: An organophosphate insecticide that has formula C7H13O6P.
Chemical ID: MESH:D008799
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Hspd1increases expressionEXP 6480464CTDMevinphos results in increased expression of HSPD1 mRNA Mevinphos results in increased expression of HSPD1 protein

PMID:17150954
Hspd1multiple interactionsEXP 6480464CTDHSPD1 protein affects the reaction [Mevinphos affects the expression of BAX protein] HSPD1 protein affects the reaction [Mevinphos affects the expression of BCL2 protein] HSPD1 protein affects the reaction [Mevinphos results in increased activity of CASP3 protein] HSPD1 protein affects the reaction [Mevinphos results in increased expression of NOS1 protein] HSPD1 protein affects the reaction [Mevinphos results in increased expression of NOS2 protein] HSPD1 protein affects the reaction [Mevinphos results in increased expression of PRKG1 protein] Mevinphos affects the reaction [HSPD1 protein binds to BCL2 protein] Mevinphos promotes the reaction [HSPD1 protein binds to BAX protein]

PMID:17150954
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