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CHEBI ONTOLOGY - ANNOTATIONS

The Chemical Entities of Biological Interest (ChEBI) ontology is downloaded weekly from EMBL-EBI at http://www.ebi.ac.uk/chebi/. The data is made available under the Creative Commons License (CC BY 3.0, http://creativecommons.org/licenses/by/3.0/). For more information see: Degtyarenko et al. (2008) ChEBI: a database and ontology for chemical entities of biological interest. Nucleic Acids Res. 36, D344–D350.

Term:tetraterpene
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Accession:CHEBI:35193 term browser browse the term
Definition:A C40 terpene.
Synonyms:related_synonym: tetraterpenes;   tetraterpeno;   tetraterpenos



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8'-apo-beta,psi-caroten-8'-al term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acadm acyl-CoA dehydrogenase medium chain increases expression ISO apocarotenal results in increased expression of ACADM mRNA CTD PMID:17034753 NCBI chr 2:242,858,865...242,883,036
Ensembl chr 2:242,858,865...242,883,147
JBrowse link
G Adh5 alcohol dehydrogenase 5 (class III), chi polypeptide increases expression ISO apocarotenal results in increased expression of ADH5 mRNA CTD PMID:17034753 NCBI chr 2:226,975,184...226,987,591 JBrowse link
G Aldh1b1 aldehyde dehydrogenase 1 family, member B1 decreases expression ISO apocarotenal results in decreased expression of ALDH1B1 mRNA CTD PMID:17034753 NCBI chr 5:60,063,370...60,068,378
Ensembl chr 5:60,063,225...60,068,378
JBrowse link
G Aldh3b1 aldehyde dehydrogenase 3 family, member B1 decreases expression ISO apocarotenal results in decreased expression of ALDH3B1 mRNA CTD PMID:17034753 NCBI chr 1:201,145,309...201,162,675
Ensembl chr 1:201,145,309...201,163,921
JBrowse link
G Aldh4a1 aldehyde dehydrogenase 4 family, member A1 decreases expression ISO apocarotenal results in decreased expression of ALDH4A1 mRNA CTD PMID:17034753 NCBI chr 5:151,880,002...151,905,491 JBrowse link
G Ank2 ankyrin 2 increases expression ISO apocarotenal results in increased expression of ANK2 mRNA CTD PMID:17034753 NCBI chr 2:215,378,028...215,954,015
Ensembl chr 2:215,379,680...215,862,923
JBrowse link
G Ank3 ankyrin 3 increases expression ISO apocarotenal results in increased expression of ANK3 mRNA CTD PMID:17034753 NCBI chr20:18,602,267...19,225,831
Ensembl chr20:18,602,786...19,086,300
JBrowse link
G Asah1 N-acylsphingosine amidohydrolase 1 increases expression ISO apocarotenal results in increased expression of ASAH1 mRNA CTD PMID:17034753 NCBI chr16:50,966,404...50,997,827
Ensembl chr16:50,966,229...51,008,233
JBrowse link
G Asb1 ankyrin repeat and SOCS box-containing 1 increases expression ISO apocarotenal results in increased expression of ASB1 mRNA CTD PMID:17034753 NCBI chr 9:92,120,332...92,140,790
Ensembl chr 9:92,120,306...92,136,376
JBrowse link
G Asb9 ankyrin repeat and SOCS box-containing 9 increases expression ISO apocarotenal results in increased expression of ASB9 mRNA CTD PMID:17034753 NCBI chr  X:29,956,576...30,001,436
Ensembl chr  X:29,956,576...30,001,105
JBrowse link
G Bax BCL2 associated X, apoptosis regulator decreases expression ISO apocarotenal results in decreased expression of BAX mRNA CTD PMID:17034753 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bco2 beta-carotene oxygenase 2 multiple interactions ISO [BCO2 protein results in increased metabolism of beta Carotene] which results in increased chemical synthesis of apocarotenal; [BCO2 protein results in increased metabolism of Cryptoxanthins] which results in increased chemical synthesis of apocarotenal; [BCO2 protein results in increased metabolism of Lutein] which results in increased chemical synthesis of apocarotenal metabolite; [BCO2 protein results in increased metabolism of Zeaxanthins] which results in increased chemical synthesis of apocarotenal metabolite CTD PMID:21106934 NCBI chr 8:50,882,174...50,907,676
Ensembl chr 8:50,882,181...50,915,467
JBrowse link
G Casp8ap2 caspase 8 associated protein 2 increases expression ISO apocarotenal results in increased expression of CASP8AP2 mRNA CTD PMID:17034753 NCBI chr 5:47,014,501...47,052,276
Ensembl chr 5:47,014,667...47,052,275
JBrowse link
G Cdh1 cadherin 1 increases expression ISO apocarotenal results in increased expression of CDH1 mRNA CTD PMID:17034753 NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775
JBrowse link
G Cldn10 claudin 10 increases expression ISO apocarotenal results in increased expression of CLDN10 mRNA CTD PMID:17034753 NCBI chr15:95,862,785...95,954,526
Ensembl chr15:95,862,760...95,954,526
JBrowse link
G Cldn18 claudin 18 increases expression ISO apocarotenal results in increased expression of CLDN18 mRNA CTD PMID:17034753 NCBI chr 8:100,246,499...100,265,797
Ensembl chr 8:100,247,633...100,273,351
JBrowse link
G Col1a1 collagen type I alpha 1 chain decreases expression ISO apocarotenal results in decreased expression of COL1A1 mRNA CTD PMID:17034753 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
JBrowse link
G Col4a1 collagen type IV alpha 1 chain decreases expression ISO apocarotenal results in decreased expression of COL4A1 mRNA CTD PMID:17034753 NCBI chr16:78,183,533...78,294,412
Ensembl chr16:78,183,533...78,294,412
JBrowse link
G Col4a2 collagen type IV alpha 2 chain decreases expression ISO apocarotenal results in decreased expression of COL4A2 mRNA CTD PMID:17034753 NCBI chr16:78,047,591...78,183,360
Ensembl chr16:78,047,602...78,183,839
JBrowse link
G Crabp2 cellular retinoic acid binding protein 2 decreases expression ISO apocarotenal results in decreased expression of CRABP2 mRNA CTD PMID:17034753 NCBI chr 2:173,417,004...173,421,352
Ensembl chr 2:173,416,857...173,421,379
JBrowse link
G Ctsb cathepsin B decreases expression ISO apocarotenal results in decreased expression of CTSB mRNA CTD PMID:17034753 NCBI chr15:37,389,636...37,410,508
Ensembl chr15:37,389,629...37,410,500
JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 increases expression ISO apocarotenal results in increased expression of CXCL12 mRNA CTD PMID:17034753 NCBI chr 4:150,388,326...150,401,173
Ensembl chr 4:150,388,325...150,401,168
JBrowse link
G Cxcl6 C-X-C motif chemokine ligand 6 increases expression ISO apocarotenal results in increased expression of CXCL6 mRNA CTD PMID:17034753 NCBI chr14:17,310,089...17,312,303
Ensembl chr14:17,310,426...17,313,093
JBrowse link
G Cxcl9 C-X-C motif chemokine ligand 9 increases expression ISO apocarotenal results in increased expression of CXCL9 mRNA CTD PMID:17034753 NCBI chr14:15,722,868...15,727,779
Ensembl chr14:15,722,908...15,728,435
JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 increases expression ISO apocarotenal results in increased expression of CXCR4 mRNA CTD PMID:17034753 NCBI chr13:40,077,976...40,081,883
Ensembl chr13:40,077,976...40,081,883
JBrowse link
G Dlx2 distal-less homeobox 2 increases expression ISO apocarotenal results in increased expression of DLX2 mRNA CTD PMID:17034753 NCBI chr 3:56,371,347...56,373,230
Ensembl chr 3:56,370,483...56,373,597
JBrowse link
G Dlx4 distal-less homeobox 4 increases expression ISO apocarotenal results in increased expression of DLX4 mRNA CTD PMID:17034753 NCBI chr10:80,085,037...80,090,434
Ensembl chr10:80,085,465...80,090,456
JBrowse link
G Ercc2 ERCC excision repair 2, TFIIH core complex helicase subunit decreases expression ISO apocarotenal results in decreased expression of ERCC2 mRNA CTD PMID:17034753 NCBI chr 1:79,033,342...79,047,102
Ensembl chr 1:79,033,326...79,047,102
JBrowse link
G Ets1 ETS proto-oncogene 1, transcription factor decreases expression ISO apocarotenal results in decreased expression of ETS1 mRNA CTD PMID:17034753 NCBI chr 8:31,045,909...31,168,010
Ensembl chr 8:31,045,945...31,168,010
JBrowse link
G Fas Fas cell surface death receptor increases expression ISO apocarotenal results in increased expression of FAS mRNA CTD PMID:17034753 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
JBrowse link
G Fasn fatty acid synthase decreases expression ISO apocarotenal results in decreased expression of FASN mRNA CTD PMID:17034753 NCBI chr10:106,072,093...106,090,259
Ensembl chr10:106,072,091...106,090,261
JBrowse link
G Gata6 GATA binding protein 6 increases expression ISO apocarotenal results in increased expression of GATA6 mRNA CTD PMID:17034753 NCBI chr18:2,188,121...2,219,532
Ensembl chr18:2,188,121...2,219,532
JBrowse link
G Gbp1 guanylate binding protein 1 increases expression ISO apocarotenal results in increased expression of GBP1 mRNA CTD PMID:17034753 NCBI chr 2:231,398,136...231,432,773
Ensembl chr 2:231,517,398...231,529,600
JBrowse link
G Gstk1 glutathione S-transferase kappa 1 decreases expression ISO apocarotenal results in decreased expression of GSTK1 mRNA CTD PMID:17034753 NCBI chr 4:71,118,979...71,123,298
Ensembl chr 4:71,118,896...71,123,292
JBrowse link
G Gstm2 glutathione S-transferase mu 2 decreases expression ISO apocarotenal results in decreased expression of GSTM2 mRNA CTD PMID:17034753 NCBI chr 2:195,624,015...195,628,774 JBrowse link
G Gstm3 glutathione S-transferase mu 3 increases expression ISO apocarotenal results in increased expression of GSTM5 mRNA CTD PMID:17034753 NCBI chr 2:195,590,450...195,612,578
Ensembl chr 2:195,607,289...195,612,475
JBrowse link
G Gstm4 glutathione S-transferase mu 4 decreases expression ISO apocarotenal results in decreased expression of GSTM4 mRNA CTD PMID:17034753 NCBI chr 2:195,667,940...195,685,315
Ensembl chr 2:195,680,004...195,685,323
JBrowse link
G Gstz1 glutathione S-transferase zeta 1 decreases expression ISO apocarotenal results in decreased expression of GSTZ1 mRNA CTD PMID:17034753 NCBI chr 6:106,794,594...106,805,284
Ensembl chr 6:106,794,074...106,805,284
JBrowse link
G Hoxa7 homeobox A7 increases expression ISO apocarotenal results in increased expression of HOXA7 mRNA CTD PMID:17034753 NCBI chr 4:81,315,730...81,317,629
Ensembl chr 4:81,314,625...81,317,659
JBrowse link
G Hoxb6 homeo box B6 increases expression ISO apocarotenal results in increased expression of HOXB6 mRNA CTD PMID:17034753 NCBI chr10:81,258,726...81,267,458
Ensembl chr10:81,265,056...81,267,449
JBrowse link
G Hoxc10 homeo box C10 increases expression ISO apocarotenal results in increased expression of HOXC10 mRNA CTD PMID:17034753 NCBI chr 7:134,103,741...134,108,966
Ensembl chr 7:134,103,643...134,108,966
JBrowse link
G Irf8 interferon regulatory factor 8 increases expression ISO apocarotenal results in increased expression of IRF8 mRNA CTD PMID:17034753 NCBI chr19:48,790,483...48,812,363
Ensembl chr19:48,790,588...48,811,829
JBrowse link
G Irx4 iroquois homeobox 4 decreases expression ISO apocarotenal results in decreased expression of IRX4 mRNA CTD PMID:17034753 NCBI chr 1:30,030,561...30,039,549
Ensembl chr 1:30,030,561...30,039,549
JBrowse link
G Itgb4 integrin subunit beta 4 decreases expression ISO apocarotenal results in decreased expression of ITGB4 mRNA CTD PMID:17034753 NCBI chr10:101,206,657...101,243,012
Ensembl chr10:101,206,665...101,243,012
JBrowse link
G Ivl involucrin increases expression ISO apocarotenal results in increased expression of IVL mRNA CTD PMID:17034753 NCBI chr 2:178,146,694...178,160,807
Ensembl chr 2:178,147,061...178,149,100
JBrowse link
G Krt17 keratin 17 decreases expression ISO apocarotenal results in decreased expression of KRT17 mRNA CTD PMID:17034753 NCBI chr10:85,178,673...85,183,392
Ensembl chr10:85,178,675...85,183,392
JBrowse link
G Krt2 keratin 2 increases expression ISO apocarotenal results in increased expression of KRT2 mRNA CTD PMID:17034753 NCBI chr 7:132,941,275...132,947,963
Ensembl chr 7:132,940,862...132,947,963
JBrowse link
G Krt7 keratin 7 affects expression ISO apocarotenal affects the expression of KRT7 mRNA CTD PMID:17034753 NCBI chr 7:132,528,863...132,545,052
Ensembl chr 7:132,528,895...132,545,052
JBrowse link
G Lhx3 LIM homeobox 3 increases expression ISO apocarotenal results in increased expression of LHX3 mRNA CTD PMID:17034753 NCBI chr 3:9,026,432...9,035,122
Ensembl chr 3:9,027,425...9,034,480
JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member affects expression ISO apocarotenal affects the expression of MCL1 mRNA CTD PMID:17034753 NCBI chr 2:183,219,137...183,235,676
Ensembl chr 2:183,219,220...183,222,303
JBrowse link
G Meis2 Meis homeobox 2 increases expression ISO apocarotenal results in increased expression of MEIS2 mRNA CTD PMID:17034753 NCBI chr 3:102,742,905...102,944,833
Ensembl chr 3:102,742,900...102,949,696
JBrowse link
G Meox1 mesenchyme homeobox 1 increases expression ISO apocarotenal results in increased expression of MEOX1 mRNA CTD PMID:17034753 NCBI chr10:86,818,450...86,837,563
Ensembl chr10:86,818,478...86,837,660
JBrowse link
G Mnx1 motor neuron and pancreas homeobox 1 increases expression ISO apocarotenal results in increased expression of MNX1 mRNA CTD PMID:17034753 NCBI chr 4:5,866,506...5,871,465
Ensembl chr 4:5,866,506...5,871,465
JBrowse link
G Msh5 mutS homolog 5 increases expression ISO apocarotenal results in increased expression of MSH5 mRNA CTD PMID:17034753 NCBI chr20:3,773,867...3,793,337
Ensembl chr20:3,776,942...3,793,336
JBrowse link
G Muc5ac mucin 5AC, oligomeric mucus/gel-forming increases expression ISO apocarotenal results in increased expression of MUC5AC mRNA CTD PMID:17034753 NCBI chr 1:196,864,375...196,896,475 JBrowse link
G Nos1 nitric oxide synthase 1 increases expression ISO apocarotenal results in increased expression of NOS1 mRNA CTD PMID:17034753 NCBI chr12:38,615,111...38,795,492
Ensembl chr12:38,626,714...38,710,945
JBrowse link
G Olr1 oxidized low density lipoprotein receptor 1 increases expression ISO apocarotenal results in increased expression of OLR1 mRNA CTD PMID:17034753 NCBI chr 4:162,926,436...162,949,057
Ensembl chr 4:162,926,439...162,948,523
JBrowse link
G Pcdhgc3 protocadherin gamma subfamily C, 3 increases expression ISO apocarotenal results in increased expression of PCDHGC3 mRNA CTD PMID:17034753 NCBI chr18:29,633,016...29,667,865 JBrowse link
G Plscr1 phospholipid scramblase 1 increases expression ISO apocarotenal results in increased expression of PLSCR1 mRNA CTD PMID:17034753 NCBI chr 8:92,784,279...92,804,698
Ensembl chr 8:92,784,356...92,804,692
JBrowse link
G Plscr3 phospholipid scramblase 3 increases expression ISO apocarotenal results in increased expression of PLSCR3 mRNA CTD PMID:17034753 NCBI chr10:54,566,556...54,573,240
Ensembl chr10:54,566,873...54,578,709
JBrowse link
G Plscr4 phospholipid scramblase 4 increases expression ISO apocarotenal results in increased expression of PLSCR4 mRNA CTD PMID:17034753 NCBI chr 8:92,987,290...93,026,056
Ensembl chr 8:92,987,381...93,026,049
JBrowse link
G Rad51ap1 RAD51 associated protein 1 increases expression ISO apocarotenal results in increased expression of RAD51AP1 mRNA CTD PMID:17034753 NCBI chr 4:159,759,454...159,772,524
Ensembl chr 4:159,759,459...159,772,524
JBrowse link
G Rad51d RAD51 paralog D increases expression ISO apocarotenal results in increased expression of RAD51D mRNA CTD PMID:17034753 NCBI chr10:67,805,720...67,824,452 JBrowse link
G Rara retinoic acid receptor, alpha decreases expression ISO apocarotenal results in decreased expression of RARA mRNA CTD PMID:17034753 NCBI chr10:83,883,490...83,928,932
Ensembl chr10:83,893,384...83,928,142
JBrowse link
G Rarb retinoic acid receptor, beta increases expression ISO apocarotenal results in increased expression of RARB mRNA CTD PMID:17034753 NCBI chr15:8,700,533...9,051,288
Ensembl chr15:8,406,492...9,051,288
JBrowse link
G Rarres1 retinoic acid receptor responder 1 increases expression ISO apocarotenal results in increased expression of RARRES1 mRNA CTD PMID:17034753 NCBI chr 2:151,749,715...151,783,975
Ensembl chr 2:151,749,715...151,783,978
JBrowse link
G Six6 SIX homeobox 6 increases expression ISO apocarotenal results in increased expression of SIX6 mRNA CTD PMID:17034753 NCBI chr 6:91,634,568...91,639,548
Ensembl chr 6:91,634,568...91,639,548
JBrowse link
G Sod1 superoxide dismutase 1 decreases expression ISO apocarotenal results in decreased expression of SOD1 mRNA CTD PMID:17034753 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
JBrowse link
G Sptlc2 serine palmitoyltransferase, long chain base subunit 2 affects expression ISO apocarotenal affects the expression of SPTLC2 mRNA CTD PMID:17034753 NCBI chr 6:106,948,681...107,031,584
Ensembl chr 6:106,950,949...107,031,542
JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 increases expression ISO apocarotenal results in increased expression of SREBF1 mRNA CTD PMID:17034753 NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650
JBrowse link
G Tgm4 transglutaminase 4 increases expression ISO apocarotenal results in increased expression of TGM4 mRNA CTD PMID:17034753 NCBI chr 8:122,689,429...122,726,463
Ensembl chr 8:122,689,429...122,726,463
JBrowse link
G Tnfrsf9 TNF receptor superfamily member 9 increases expression ISO apocarotenal results in increased expression of TNFRSF9 mRNA CTD PMID:17034753 NCBI chr 5:161,381,662...161,408,003
Ensembl chr 5:161,381,662...161,408,000
JBrowse link
G Tnfsf10 TNF superfamily member 10 increases expression ISO apocarotenal results in increased expression of TNFSF10 mRNA CTD PMID:17034753 NCBI chr 2:110,199,835...110,227,239
Ensembl chr 2:110,207,916...110,225,135
JBrowse link
G Txndc9 thioredoxin domain containing 9 increases expression ISO apocarotenal results in increased expression of TXNDC9 mRNA CTD PMID:17034753 NCBI chr 9:40,211,818...40,221,953
Ensembl chr 9:40,211,412...40,384,279
JBrowse link
G Xrcc3 X-ray repair cross complementing 3 increases expression ISO apocarotenal results in increased expression of XRCC3 mRNA CTD PMID:17034753 NCBI chr 6:130,863,405...130,873,765
Ensembl chr 6:130,863,959...130,872,444
JBrowse link
9'-cis-neoxanthin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aifm1 apoptosis inducing factor, mitochondria associated 1 affects localization ISO neoxanthin affects the localization of AIFM1 protein CTD PMID:17186379 NCBI chr  X:127,650,223...127,689,356
Ensembl chr  X:127,650,226...127,689,256
JBrowse link
G Casp3 caspase 3 multiple interactions ISO neoxanthin results in increased cleavage of and results in increased activity of CASP3 protein CTD PMID:17186379 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp8 caspase 8 increases activity ISO neoxanthin results in increased activity of CASP8 protein CTD PMID:17186379 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Casp9 caspase 9 multiple interactions ISO neoxanthin results in increased cleavage of and results in increased activity of CASP9 protein CTD PMID:17186379 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
all-trans-neoxanthin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aifm1 apoptosis inducing factor, mitochondria associated 1 affects localization ISO neoxanthin affects the localization of AIFM1 protein CTD PMID:17186379 NCBI chr  X:127,650,223...127,689,356
Ensembl chr  X:127,650,226...127,689,256
JBrowse link
G Casp3 caspase 3 multiple interactions ISO neoxanthin results in increased cleavage of and results in increased activity of CASP3 protein CTD PMID:17186379 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp8 caspase 8 increases activity ISO neoxanthin results in increased activity of CASP8 protein CTD PMID:17186379 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Casp9 caspase 9 multiple interactions ISO neoxanthin results in increased cleavage of and results in increased activity of CASP9 protein CTD PMID:17186379 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
all-trans-phytoene term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Esr1 estrogen receptor 1 multiple interactions ISO [(all-E) phytoene co-treated with phytofluene] inhibits the reaction [Estradiol results in increased activity of ESR1 protein] CTD PMID:17051425 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
JBrowse link
G Esr2 estrogen receptor 2 multiple interactions ISO [(all-E) phytoene co-treated with phytofluene] inhibits the reaction [Estradiol results in increased activity of ESR2 protein] CTD PMID:17051425 NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919
JBrowse link
all-trans-phytofluene term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Esr1 estrogen receptor 1 multiple interactions ISO [(all-E) phytoene co-treated with phytofluene] inhibits the reaction [Estradiol results in increased activity of ESR1 protein] CTD PMID:17051425 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
JBrowse link
G Esr2 estrogen receptor 2 multiple interactions ISO [(all-E) phytoene co-treated with phytofluene] inhibits the reaction [Estradiol results in increased activity of ESR2 protein] CTD PMID:17051425 NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919
JBrowse link
alpha-carotene term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Mgmt O-6-methylguanine-DNA methyltransferase affects response to substance ISO MGMT gene SNP affects the susceptibility to alpha-carotene CTD PMID:16014702 NCBI chr 1:191,710,980...191,937,760
Ensembl chr 1:191,710,930...191,937,756
JBrowse link
astaxanthin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Aifm1 apoptosis inducing factor, mitochondria associated 1 multiple interactions ISO astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of AIFM1 mRNA] CTD PMID:16964424 NCBI chr  X:127,650,223...127,689,356
Ensembl chr  X:127,650,226...127,689,256
JBrowse link
G App amyloid beta precursor protein multiple interactions ISO astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of APP mRNA] CTD PMID:16964424 NCBI chr11:24,019,774...24,236,584
Ensembl chr11:24,019,778...24,236,561
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions ISO astaxanthine inhibits the reaction [Hydrogen Peroxide results in increased expression of BAX mRNA] CTD PMID:33212048 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G C1qa complement C1q A chain decreases expression ISO astaxanthine results in decreased expression of C1QA mRNA CTD PMID:19555370 NCBI chr 5:149,133,635...149,136,482
Ensembl chr 5:149,133,636...149,136,534
JBrowse link
G Casp3 caspase 3 multiple interactions ISO astaxanthine inhibits the reaction [Hydrogen Peroxide results in increased expression of CASP3 mRNA] CTD PMID:33212048 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Cat catalase multiple interactions ISO astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of CAT mRNA] CTD PMID:16964424 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Cntd1 cyclin N-terminal domain containing 1 multiple interactions ISO astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of CNTD1 mRNA] CTD PMID:16964424 NCBI chr10:86,221,430...86,231,812 JBrowse link
G Cox15 cytochrome c oxidase assembly homolog COX15 multiple interactions ISO astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of COX15 mRNA] CTD PMID:16964424 NCBI chr 1:242,605,588...242,622,279
Ensembl chr 1:242,605,588...242,622,261
JBrowse link
G Cox5a cytochrome c oxidase subunit 5A multiple interactions ISO astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of COX5A mRNA] CTD PMID:16964424 NCBI chr 8:57,922,374...57,933,781
Ensembl chr 8:57,922,290...57,933,781
JBrowse link
G Cox5b cytochrome c oxidase subunit 5B multiple interactions ISO astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of COX5B mRNA] CTD PMID:16964424 NCBI chr 9:38,921,980...38,923,806
Ensembl chr 9:38,921,967...38,925,052
JBrowse link
G Cox6b1 cytochrome c oxidase subunit 6B1 multiple interactions ISO astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of COX6B1 mRNA] CTD PMID:16964424 NCBI chr 1:85,875,080...85,884,081
Ensembl chr 1:85,875,109...85,884,001
JBrowse link
G Cox6c cytochrome c oxidase subunit 6C multiple interactions ISO astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of COX6C mRNA] CTD PMID:16964424 NCBI chr 7:67,129,265...67,142,001
Ensembl chr 7:67,111,024...67,141,963
JBrowse link
G Ctss cathepsin S decreases expression ISO astaxanthine results in decreased expression of CTSS mRNA CTD PMID:19555370 NCBI chr 2:183,089,192...183,114,483
Ensembl chr 2:183,086,437...183,114,483
JBrowse link
G Cybb cytochrome b-245 beta chain multiple interactions
decreases expression
EXP astaxanthine inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of CYBB mRNA]; astaxanthine inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of CYBB protein]; tin protoporphyrin IX inhibits the reaction [astaxanthine inhibits the reaction [1-Methyl-4-phenylpyridinium results in increased expression of CYBB mRNA]]
astaxanthine results in decreased expression of CYBB mRNA
CTD PMID:23272707 NCBI chr  X:13,360,583...13,392,517
Ensembl chr  X:13,359,430...13,392,586
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 multiple interactions
increases expression
EXP astaxanthine results in increased expression of and results in increased activity of CYP1A1 protein
astaxanthine results in increased expression of CYP1A1 mRNA
CTD PMID:21414371 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Foxo3 forkhead box O3 multiple interactions ISO astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of FOXO3 mRNA] CTD PMID:16964424 NCBI chr20:45,669,708...45,764,606
Ensembl chr20:45,672,995...45,764,561
JBrowse link
G G6pd glucose-6-phosphate dehydrogenase increases activity
multiple interactions
EXP astaxanthine results in increased activity of G6PD protein
[Cadmium co-treated with astaxanthine] results in decreased activity of G6PD protein
CTD PMID:28665548 PMID:29975440 NCBI chr  X:152,201,081...152,220,863
Ensembl chr  X:152,201,098...152,220,801
JBrowse link
G Gfap glial fibrillary acidic protein decreases expression ISO astaxanthine results in decreased expression of GFAP mRNA CTD PMID:19555370 NCBI chr10:87,852,891...87,861,631
Ensembl chr10:87,852,890...87,861,589
JBrowse link
G Gja1 gap junction protein, alpha 1 increases expression
multiple interactions
ISO astaxanthine results in increased expression of GJA1 protein
2-chloro-5-nitrobenzanilide inhibits the reaction [astaxanthine results in increased expression of GJA1 protein]; astaxanthine promotes the reaction [4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid results in increased expression of GJA1 protein]
CTD PMID:16091010 NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582
JBrowse link
G Gna13 G protein subunit alpha 13 multiple interactions ISO astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of GNA13 mRNA] CTD PMID:16964424 NCBI chr10:94,337,939...94,370,774
Ensembl chr10:94,337,725...94,370,774
JBrowse link
G Gpx3 glutathione peroxidase 3 multiple interactions ISO astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of GPX3 mRNA] CTD PMID:16964424 NCBI chr10:39,028,624...39,036,695
Ensembl chr10:39,028,570...39,037,035
JBrowse link
G Grin1 glutamate ionotropic receptor NMDA type subunit 1 multiple interactions EXP [mithramycin A co-treated with astaxanthine] inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of GRIN1 protein]; astaxanthine inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of GRIN1 mRNA]; astaxanthine inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of GRIN1 protein]; astaxanthine promotes the reaction [mithramycin A inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of GRIN1 mRNA]]; astaxanthine promotes the reaction [mithramycin A inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of GRIN1 protein]]; mithramycin A promotes the reaction [astaxanthine inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of GRIN1 mRNA]]; mithramycin A promotes the reaction [astaxanthine inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of GRIN1 protein]] CTD PMID:23538867 NCBI chr 3:8,103,680...8,130,603
Ensembl chr 3:8,103,680...8,130,603
JBrowse link
G Grn granulin precursor multiple interactions ISO astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of GRN mRNA] CTD PMID:16964424 NCBI chr10:87,387,672...87,393,777
Ensembl chr10:87,387,638...87,393,775
JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions EXP astaxanthine inhibits the reaction [Cadmium results in decreased activity of GSR protein] CTD PMID:29975440 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
JBrowse link
G Gstm2 glutathione S-transferase mu 2 multiple interactions
increases expression
ISO [astaxanthine co-treated with Docosahexaenoic Acids] results in increased expression of GSTM2 mRNA; [astaxanthine co-treated with Eicosapentaenoic Acid] results in increased expression of GSTM2 mRNA
astaxanthine results in increased expression of GSTM2 mRNA
CTD PMID:24157545 NCBI chr 2:195,624,015...195,628,774 JBrowse link
G Hmgb1 high mobility group box 1 multiple interactions ISO astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of HMGB1 mRNA] CTD PMID:16964424 NCBI chr12:5,973,062...5,978,565 JBrowse link
G Hmox1 heme oxygenase 1 increases expression
decreases expression
multiple interactions
EXP
ISO
astaxanthine results in increased expression of HMOX1 protein
astaxanthine results in decreased expression of HMOX1 mRNA
[astaxanthine co-treated with Cyclophosphamide] results in increased expression of HMOX1 protein; astaxanthine promotes the reaction [1-Methyl-4-phenylpyridinium results in increased expression of HMOX1 mRNA]; astaxanthine promotes the reaction [1-Methyl-4-phenylpyridinium results in increased expression of HMOX1 protein]; tin protoporphyrin IX inhibits the reaction [astaxanthine promotes the reaction [1-Methyl-4-phenylpyridinium results in increased expression of HMOX1 mRNA]]; tin protoporphyrin IX inhibits the reaction [astaxanthine promotes the reaction [1-Methyl-4-phenylpyridinium results in increased expression of HMOX1 protein]]
astaxanthine results in increased expression of HMOX1 mRNA
[astaxanthine co-treated with Docosahexaenoic Acids] results in increased expression of HMOX1 mRNA; [astaxanthine co-treated with Eicosapentaenoic Acid] results in increased expression of HMOX1 mRNA; astaxanthine inhibits the reaction [Hydrogen Peroxide results in increased expression of HMOX1 mRNA]
CTD PMID:20038455 PMID:23272707 PMID:24157545 PMID:33212048 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hoxa9 homeobox A9 multiple interactions ISO astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of HOXA9 mRNA] CTD PMID:16964424 NCBI chr 4:81,323,235...81,329,344 JBrowse link
G Idh1 isocitrate dehydrogenase (NADP(+)) 1 multiple interactions ISO astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of IDH1 mRNA] CTD PMID:16964424 NCBI chr 9:66,534,146...66,563,703
Ensembl chr 9:66,534,146...66,563,708
JBrowse link
G Ifng interferon gamma increases expression ISO astaxanthine results in increased expression of IFNG protein CTD PMID:33132140 NCBI chr 7:53,903,339...53,907,375
Ensembl chr 7:53,903,337...53,907,375
JBrowse link
G Il11 interleukin 11 increases expression ISO astaxanthine results in increased expression of IL11 protein CTD PMID:33132140 NCBI chr 1:69,069,829...69,076,129
Ensembl chr 1:69,068,137...69,076,129
JBrowse link
G Il1b interleukin 1 beta decreases expression ISO astaxanthine results in decreased expression of IL1B mRNA; astaxanthine results in decreased expression of IL1B protein CTD PMID:21621527 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il6 interleukin 6 decreases expression ISO astaxanthine results in decreased expression of IL6 mRNA CTD PMID:21621527 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Lepr leptin receptor multiple interactions ISO astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of AIFM1 mRNA]; astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of APP mRNA]; astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of CAT mRNA]; astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of CNTD1 mRNA]; astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of COX15 mRNA]; astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of COX5A mRNA]; astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of COX5B mRNA]; astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of COX6B1 mRNA]; astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of COX6C mRNA]; astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of FOXO3 mRNA]; astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of GNA13 mRNA]; astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of GPX3 mRNA]; astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of GRN mRNA]; astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of HMGB1 mRNA]; astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of HOXA9 mRNA]; astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of IDH1 mRNA]; astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of ND6 mRNA]; astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of NDUFA1 mRNA]; astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of NDUFA5 mRNA]; astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of NDUFC2 mRNA]; astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of NDUFV2 mRNA]; astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of NME2 mRNA]; astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of PPP1CB mRNA]; astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of PRDX1 mRNA]; astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of RPS2 mRNA]; astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of SOD1 mRNA]; astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of SPP1 mRNA]; astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of TGM2 mRNA]; astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of TKT mRNA]; astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of UBB mRNA]; astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of UQCRB mRNA]; astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of UQCRC2 mRNA] CTD PMID:16964424 NCBI chr 5:116,294,409...116,477,904
Ensembl chr 5:116,289,823...116,475,908
JBrowse link
G Mt-nd6 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 6 multiple interactions ISO astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of ND6 mRNA] CTD PMID:16964424 NCBI chr MT:13,543...14,061
Ensembl chr MT:13,543...14,061
JBrowse link
G Ndufa1 NADH:ubiquinone oxidoreductase subunit A1 multiple interactions ISO astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of NDUFA1 mRNA] CTD PMID:16964424 NCBI chr  X:116,424,223...116,427,875
Ensembl chr  X:116,424,223...116,428,633
JBrowse link
G Ndufa5 NADH:ubiquinone oxidoreductase subunit A5 multiple interactions ISO astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of NDUFA5 mRNA] CTD PMID:16964424 NCBI chr 4:52,997,327...53,005,685
Ensembl chr 4:52,995,546...53,005,598
JBrowse link
G Ndufc2 NADH:ubiquinone oxidoreductase subunit C2 multiple interactions ISO astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of NDUFC2 mRNA] CTD PMID:16964424 NCBI chr 1:151,711,965...151,718,188
Ensembl chr 1:151,711,901...151,718,189
JBrowse link
G Ndufv2 NADH:ubiquinone oxidoreductase core subunit V2 multiple interactions ISO astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of NDUFV2 mRNA] CTD PMID:16964424 NCBI chr 9:105,690,454...105,710,669
Ensembl chr 9:105,690,455...105,710,713
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 increases expression
multiple interactions
EXP
ISO
astaxanthine results in increased expression of NFE2L2 protein
[astaxanthine co-treated with Cyclophosphamide] results in increased expression of NFE2L2 protein; astaxanthine promotes the reaction [1-Methyl-4-phenylpyridinium results in increased expression of NFE2L2 protein]; tin protoporphyrin IX inhibits the reaction [astaxanthine promotes the reaction [1-Methyl-4-phenylpyridinium results in increased expression of NFE2L2 protein]]
astaxanthine results in increased expression of NFE2L2 mRNA
[astaxanthine co-treated with Docosahexaenoic Acids] results in increased expression of NFE2L2 mRNA; [astaxanthine co-treated with Eicosapentaenoic Acid] results in increased expression of NFE2L2 mRNA; astaxanthine promotes the reaction [Hydrogen Peroxide results in increased expression of NFE2L2 mRNA]
CTD PMID:20038455 PMID:23272707 PMID:24157545 PMID:33212048 NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nme2 NME/NM23 nucleoside diphosphate kinase 2 multiple interactions ISO astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of NME2 mRNA] CTD PMID:16964424 NCBI chr10:78,898,097...78,903,600
Ensembl chr10:78,897,770...78,903,538
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 multiple interactions
increases expression
EXP
ISO
[astaxanthine co-treated with Cyclophosphamide] results in increased expression of NQO1 protein
[astaxanthine co-treated with Docosahexaenoic Acids] results in increased expression of NQO1 mRNA; [astaxanthine co-treated with Eicosapentaenoic Acid] results in increased expression of NQO1 mRNA; astaxanthine inhibits the reaction [Hydrogen Peroxide results in increased expression of NQO1 mRNA]
astaxanthine results in increased expression of NQO1 mRNA
astaxanthine results in increased expression of NQO1 protein
CTD PMID:20038455 PMID:24157545 PMID:33212048 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G Pah phenylalanine hydroxylase decreases expression ISO astaxanthine results in decreased expression of PAH mRNA CTD PMID:19555370 NCBI chr 7:21,933,179...21,998,134
Ensembl chr 7:21,933,179...21,998,130
JBrowse link
G Pgd phosphogluconate dehydrogenase increases activity EXP astaxanthine results in increased activity of PGD protein CTD PMID:28665548 PMID:29975440 NCBI chr 5:159,582,746...159,598,945 JBrowse link
G Por cytochrome p450 oxidoreductase decreases activity
increases expression
EXP astaxanthine results in decreased activity of POR protein
astaxanthine results in increased expression of POR protein
CTD PMID:21414371 NCBI chr12:20,951,058...20,999,198
Ensembl chr12:20,951,058...20,999,245
JBrowse link
G Ppp1cb protein phosphatase 1 catalytic subunit beta multiple interactions ISO astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of PPP1CB mRNA] CTD PMID:16964424 NCBI chr 6:23,958,813...23,992,841
Ensembl chr 6:23,960,998...23,992,824
JBrowse link
G Prdx1 peroxiredoxin 1 multiple interactions ISO astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of PRDX1 mRNA] CTD PMID:16964424 NCBI chr 5:130,147,276...130,162,850
Ensembl chr 5:130,147,204...130,162,856
JBrowse link
G Pten phosphatase and tensin homolog multiple interactions ISO astaxanthine inhibits the reaction [Hydrogen Peroxide results in increased expression of PTEN mRNA] CTD PMID:33212048 NCBI chr 1:230,631,303...230,696,754
Ensembl chr 1:230,630,338...230,696,838
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 decreases expression ISO astaxanthine results in decreased expression of PTGS2 mRNA CTD PMID:21621527 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Rps2 ribosomal protein S2 multiple interactions ISO astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of RPS2 mRNA] CTD PMID:16964424 NCBI chr10:13,747,316...13,749,165
Ensembl chr10:13,747,301...13,749,163
JBrowse link
G Skap2 src kinase associated phosphoprotein 2 decreases expression ISO astaxanthine results in decreased expression of SKAP2 mRNA CTD PMID:19555370 NCBI chr 4:80,948,832...81,100,900
Ensembl chr 4:80,950,580...81,100,891
JBrowse link
G Sod1 superoxide dismutase 1 multiple interactions ISO astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of SOD1 mRNA] CTD PMID:16964424 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
JBrowse link
G Sp1 Sp1 transcription factor multiple interactions EXP [mithramycin A co-treated with astaxanthine] inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of and affects the localization of SP1 protein]; astaxanthine inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of SP1 mRNA]; astaxanthine inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of SP1 protein]; astaxanthine promotes the reaction [mithramycin A inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of SP1 mRNA]]; astaxanthine promotes the reaction [mithramycin A inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of SP1 protein]]; mithramycin A promotes the reaction [astaxanthine inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of SP1 mRNA]]; mithramycin A promotes the reaction [astaxanthine inhibits the reaction [1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine results in increased expression of SP1 protein]] CTD PMID:23538867 NCBI chr 7:133,541,302...133,571,961
Ensembl chr 7:133,541,491...133,571,961
JBrowse link
G Spp1 secreted phosphoprotein 1 multiple interactions ISO astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of SPP1 mRNA] CTD PMID:16964424 NCBI chr14:5,308,885...5,315,120
Ensembl chr14:5,308,885...5,315,162
JBrowse link
G Tgm2 transglutaminase 2 multiple interactions ISO astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of TGM2 mRNA] CTD PMID:16964424 NCBI chr 3:146,772,684...146,801,924
Ensembl chr 3:146,772,687...146,801,981
JBrowse link
G Tkt transketolase multiple interactions ISO astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of TKT mRNA] CTD PMID:16964424 NCBI chr16:5,723,764...5,748,702
Ensembl chr16:5,723,762...5,748,698
JBrowse link
G Tnf tumor necrosis factor decreases expression
increases expression
ISO astaxanthine results in decreased expression of TNF protein
astaxanthine results in increased expression of TNF protein
CTD PMID:21621527 PMID:33132140 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tp53 tumor protein p53 multiple interactions EXP astaxanthine inhibits the reaction [Cyclophosphamide results in increased expression of TP53 protein] CTD PMID:20038455 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Ubb ubiquitin B multiple interactions ISO astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of UBB mRNA] CTD PMID:16964424 NCBI chr10:47,247,629...47,249,335
Ensembl chr10:47,245,637...47,249,333
JBrowse link
G Uqcrb ubiquinol-cytochrome c reductase binding protein multiple interactions ISO astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of UQCRB mRNA] CTD PMID:16964424 NCBI chr 7:63,814,784...63,820,150
Ensembl chr 7:63,814,797...63,820,150
JBrowse link
G Uqcrc2 ubiquinol cytochrome c reductase core protein 2 multiple interactions ISO astaxanthine inhibits the reaction [LEPR gene mutant form results in increased expression of UQCRC2 mRNA] CTD PMID:16964424 NCBI chr 1:175,167,933...175,198,499
Ensembl chr 1:175,167,894...175,199,453
JBrowse link
beta-carotene term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acad9 acyl-CoA dehydrogenase family, member 9 multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of ACAD9 mRNA CTD PMID:24657404 NCBI chr 2:118,943,170...118,966,150
Ensembl chr 2:118,943,174...118,966,547
JBrowse link
G Adh5 alcohol dehydrogenase 5 (class III), chi polypeptide increases expression ISO beta Carotene results in increased expression of ADH5 mRNA CTD PMID:17034753 NCBI chr 2:226,975,184...226,987,591 JBrowse link
G Adipoq adiponectin, C1Q and collagen domain containing decreases expression ISO beta Carotene results in decreased expression of ADIPOQ mRNA CTD PMID:21569430 NCBI chr11:77,721,912...77,735,644
Ensembl chr11:77,721,912...77,735,564
JBrowse link
G Aebp1 AE binding protein 1 multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of AEBP1 mRNA CTD PMID:24657404 NCBI chr14:80,738,800...80,748,878
Ensembl chr14:80,738,892...80,748,877
JBrowse link
G Akt1 AKT serine/threonine kinase 1 decreases phosphorylation ISO beta Carotene results in decreased phosphorylation of AKT1 protein CTD PMID:26733226 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Alad aminolevulinate dehydratase multiple interactions ISO beta Carotene inhibits the reaction [arsenic trioxide results in decreased expression of ALAD protein] CTD PMID:25542264 NCBI chr 5:75,961,993...75,972,334
Ensembl chr 5:75,961,993...75,972,474
JBrowse link
G Aldh3b1 aldehyde dehydrogenase 3 family, member B1 decreases expression ISO beta Carotene results in decreased expression of ALDH3B1 mRNA CTD PMID:17034753 NCBI chr 1:201,145,309...201,162,675
Ensembl chr 1:201,145,309...201,163,921
JBrowse link
G Aldh4a1 aldehyde dehydrogenase 4 family, member A1 decreases expression ISO beta Carotene results in decreased expression of ALDH4A1 mRNA CTD PMID:17034753 NCBI chr 5:151,880,002...151,905,491 JBrowse link
G Ank2 ankyrin 2 increases expression ISO beta Carotene results in increased expression of ANK2 mRNA CTD PMID:17034753 NCBI chr 2:215,378,028...215,954,015
Ensembl chr 2:215,379,680...215,862,923
JBrowse link
G Ank3 ankyrin 3 increases expression ISO beta Carotene results in increased expression of ANK3 mRNA CTD PMID:17034753 NCBI chr20:18,602,267...19,225,831
Ensembl chr20:18,602,786...19,086,300
JBrowse link
G Appbp2 amyloid beta precursor protein binding protein 2 multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of APPBP2 mRNA CTD PMID:24657404 NCBI chr10:70,057,774...70,099,877
Ensembl chr10:70,057,774...70,099,835
JBrowse link
G Arhgap26 Rho GTPase activating protein 26 multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of ARHGAP26 mRNA CTD PMID:24657404 NCBI chr18:30,835,806...31,237,945
Ensembl chr18:30,838,671...31,235,194
JBrowse link
G Asah1 N-acylsphingosine amidohydrolase 1 increases expression ISO beta Carotene results in increased expression of ASAH1 mRNA CTD PMID:17034753 NCBI chr16:50,966,404...50,997,827
Ensembl chr16:50,966,229...51,008,233
JBrowse link
G Asb1 ankyrin repeat and SOCS box-containing 1 increases expression ISO beta Carotene results in increased expression of ASB1 mRNA CTD PMID:17034753 NCBI chr 9:92,120,332...92,140,790
Ensembl chr 9:92,120,306...92,136,376
JBrowse link
G Asb9 ankyrin repeat and SOCS box-containing 9 increases expression ISO beta Carotene results in increased expression of ASB9 mRNA CTD PMID:17034753 NCBI chr  X:29,956,576...30,001,436
Ensembl chr  X:29,956,576...30,001,105
JBrowse link
G Atp8b1 ATPase phospholipid transporting 8B1 multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of ATP8B1 mRNA CTD PMID:24657404 NCBI chr18:58,016,382...58,157,213
Ensembl chr18:58,018,268...58,157,396
JBrowse link
G Bag3 BAG cochaperone 3 decreases expression ISO beta Carotene results in decreased expression of BAG3 mRNA CTD PMID:17034753 NCBI chr 1:183,103,038...183,126,862
Ensembl chr 1:183,102,871...183,126,858
JBrowse link
G Bag4 BAG cochaperone 4 decreases expression ISO beta Carotene results in decreased expression of BAG4 mRNA CTD PMID:17034753 NCBI chr16:66,288,678...66,305,893
Ensembl chr16:66,288,678...66,308,663
JBrowse link
G Bag5 BAG cochaperone 5 decreases expression ISO beta Carotene results in decreased expression of BAG5 mRNA CTD PMID:17034753 NCBI chr 6:130,768,467...130,772,122
Ensembl chr 6:130,768,141...130,772,970
JBrowse link
G Bax BCL2 associated X, apoptosis regulator decreases expression
increases expression
ISO beta Carotene results in decreased expression of BAX mRNA
beta Carotene results in increased expression of BAX mRNA; beta Carotene results in increased expression of BAX protein
CTD PMID:15949688 PMID:17034753 PMID:26733226 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression ISO beta Carotene results in decreased expression of BCL2 protein CTD PMID:26733226 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Bco1 beta-carotene oxygenase 1 multiple interactions
affects response to substance
increases oxidation
increases expression
ISO
EXP
beta Carotene results in increased expression of and results in increased activity of BCO1 protein
[BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of ACAD9 mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of AEBP1 mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of APPBP2 mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of ARHGAP26 mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of ATP8B1 mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of CDCA8 mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of CENPE mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of CLCN3 mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of COQ7 mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of CTNNAL1 mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of DHFR mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of DTWD2 mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of EDN1 mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of EIF2S1 mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of FOXM1 mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of FZD6 mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of IRX4 mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of ITM2A mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of KIF11 mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of LANCL1 mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of LMNB2 mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of METTL21A mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of METTL9 mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of MRPL57 mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of MTCH2 mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of NCKAP1 mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of NOM1 mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of PARD6A mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of PCDH1 mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of PLAT mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of RPP14 mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of RRM1 mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of TFCP2 mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of THOC7 mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of TMEM209 mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of TTC21B mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of TWF1 mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of TYMP mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of YTHDC2 mRNA; [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of ZDHHC3 mRNA
BCO1 protein results in increased oxidation of beta Carotene
beta Carotene results in increased expression of BCO1 mRNA
Ascorbic Acid inhibits the reaction [Oxidants inhibits the reaction [BCO1 protein results in increased oxidation of beta Carotene]]; Oxidants inhibits the reaction [BCO1 protein results in increased oxidation of beta Carotene]; Vitamin E inhibits the reaction [Oxidants inhibits the reaction [BCO1 protein results in increased oxidation of beta Carotene]]
CTD PMID:9526112 PMID:16186334 PMID:24657404 NCBI chr19:45,149,250...45,186,102
Ensembl chr19:45,149,265...45,186,101
JBrowse link
G Bco2 beta-carotene oxygenase 2 multiple interactions
increases metabolic processing
ISO [BCO2 protein results in increased metabolism of beta Carotene] which results in increased chemical synthesis of apocarotenal CTD PMID:21106934 NCBI chr 8:50,882,174...50,907,676
Ensembl chr 8:50,882,181...50,915,467
JBrowse link
G Casp3 caspase 3 multiple interactions
increases activity
ISO alpha-Tocopherol promotes the reaction [beta Carotene metabolite results in decreased activity of CASP3 protein]
beta Carotene metabolite results in increased activity of CASP3 protein; beta Carotene results in increased activity of CASP3 protein
CTD PMID:17618090 PMID:26733226 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Cat catalase multiple interactions EXP
ISO
[Ascorbic Acid co-treated with beta Carotene co-treated with alpha-Tocopherol co-treated with Sodium Selenite] inhibits the reaction [Galactosamine results in increased activity of CAT protein]; beta Carotene inhibits the reaction [cholestane-3,5,6-triol results in decreased activity of CAT protein]; beta Carotene inhibits the reaction [Indomethacin results in decreased expression of CAT protein]
beta Carotene inhibits the reaction [arsenic trioxide results in decreased activity of CAT protein]
CTD PMID:9306888 PMID:12500499 PMID:25542264 PMID:31022331 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Cav1 caveolin 1 decreases expression ISO beta Carotene results in decreased expression of CAV1 protein CTD PMID:26733226 NCBI chr 4:45,640,624...45,673,708
Ensembl chr 4:45,634,918...45,673,705
JBrowse link
G Ccnd1 cyclin D1 decreases expression ISO beta Carotene results in decreased expression of CCND1 protein CTD PMID:26733226 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Cdca8 cell division cycle associated 8 multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of CDCA8 mRNA CTD PMID:24657404 NCBI chr 5:137,176,414...137,198,686
Ensembl chr 5:137,176,417...137,198,629
JBrowse link
G Cdh1 cadherin 1 increases expression ISO beta Carotene results in increased expression of CDH1 mRNA; beta Carotene results in increased expression of CDH1 protein CTD PMID:17034753 PMID:26733226 NCBI chr19:34,492,371...34,561,775
Ensembl chr19:34,492,371...34,561,775
JBrowse link
G Cebpa CCAAT/enhancer binding protein alpha decreases expression ISO beta Carotene results in decreased expression of CEBPA mRNA CTD PMID:21569430 NCBI chr 1:87,759,631...87,762,303
Ensembl chr 1:87,759,433...87,762,412
JBrowse link
G Cenpe centromere protein E multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of CENPE mRNA CTD PMID:24657404 NCBI chr 2:223,637,035...223,695,692
Ensembl chr 2:223,636,998...223,695,669
JBrowse link
G Cflar CASP8 and FADD-like apoptosis regulator increases expression ISO beta Carotene results in increased expression of CFLAR mRNA CTD PMID:17034753 NCBI chr 9:60,185,338...60,236,173
Ensembl chr 9:60,185,452...60,237,034
JBrowse link
G Clcn3 chloride voltage-gated channel 3 multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of CLCN3 mRNA CTD PMID:24657404 NCBI chr16:29,127,419...29,200,133
Ensembl chr16:29,127,419...29,200,119
JBrowse link
G Cldn10 claudin 10 increases expression ISO beta Carotene results in increased expression of CLDN10 mRNA CTD PMID:17034753 NCBI chr15:95,862,785...95,954,526
Ensembl chr15:95,862,760...95,954,526
JBrowse link
G Cldn18 claudin 18 increases expression ISO beta Carotene results in increased expression of CLDN18 mRNA CTD PMID:17034753 NCBI chr 8:100,246,499...100,265,797
Ensembl chr 8:100,247,633...100,273,351
JBrowse link
G Col1a1 collagen type I alpha 1 chain decreases expression ISO beta Carotene results in decreased expression of COL1A1 mRNA CTD PMID:17034753 NCBI chr10:79,883,622...79,900,625
Ensembl chr10:79,883,622...79,900,624
JBrowse link
G Col4a1 collagen type IV alpha 1 chain decreases expression ISO beta Carotene results in decreased expression of COL4A1 mRNA CTD PMID:17034753 NCBI chr16:78,183,533...78,294,412
Ensembl chr16:78,183,533...78,294,412
JBrowse link
G Col4a2 collagen type IV alpha 2 chain decreases expression ISO beta Carotene results in decreased expression of COL4A2 mRNA CTD PMID:17034753 NCBI chr16:78,047,591...78,183,360
Ensembl chr16:78,047,602...78,183,839
JBrowse link
G Coq7 coenzyme Q7, hydroxylase multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of COQ7 mRNA CTD PMID:24657404 NCBI chr 1:172,836,359...172,851,173
Ensembl chr 1:172,835,188...172,851,158
JBrowse link
G Cpt1b carnitine palmitoyltransferase 1B decreases expression ISO beta Carotene results in decreased expression of CPT1B mRNA CTD PMID:21569430 NCBI chr 7:120,491,354...120,500,833
Ensembl chr 7:120,491,354...120,500,404
JBrowse link
G Cradd CASP2 and RIPK1 domain containing adaptor with death domain increases expression ISO beta Carotene results in increased expression of CRADD mRNA CTD PMID:17034753 NCBI chr 7:29,940,240...29,952,907
Ensembl chr 7:29,798,586...29,952,907
JBrowse link
G Ctnnal1 catenin alpha-like 1 multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of CTNNAL1 mRNA CTD PMID:24657404 NCBI chr 5:71,514,340...71,569,431
Ensembl chr 5:71,514,340...71,569,431
JBrowse link
G Ctsb cathepsin B decreases expression ISO beta Carotene results in decreased expression of CTSB mRNA CTD PMID:17034753 NCBI chr15:37,389,636...37,410,508
Ensembl chr15:37,389,629...37,410,500
JBrowse link
G Cxcl12 C-X-C motif chemokine ligand 12 increases expression ISO beta Carotene results in increased expression of CXCL12 mRNA CTD PMID:17034753 NCBI chr 4:150,388,326...150,401,173
Ensembl chr 4:150,388,325...150,401,168
JBrowse link
G Cxcl6 C-X-C motif chemokine ligand 6 increases expression ISO beta Carotene results in increased expression of CXCL6 mRNA CTD PMID:17034753 NCBI chr14:17,310,089...17,312,303
Ensembl chr14:17,310,426...17,313,093
JBrowse link
G Cxcl9 C-X-C motif chemokine ligand 9 increases expression ISO beta Carotene results in increased expression of CXCL9 mRNA CTD PMID:17034753 NCBI chr14:15,722,868...15,727,779
Ensembl chr14:15,722,908...15,728,435
JBrowse link
G Cxcr4 C-X-C motif chemokine receptor 4 increases expression ISO beta Carotene results in increased expression of CXCR4 mRNA CTD PMID:17034753 NCBI chr13:40,077,976...40,081,883
Ensembl chr13:40,077,976...40,081,883
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions ISO beta Carotene promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 protein]; Quercetin inhibits the reaction [beta Carotene promotes the reaction [Benzo(a)pyrene results in increased expression of CYP1A2 protein]] CTD PMID:16970932 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
G Cyp26a1 cytochrome P450, family 26, subfamily a, polypeptide 1 increases expression ISO beta Carotene results in increased expression of CYP26A1 mRNA CTD PMID:16186334 PMID:22542753 NCBI chr 1:235,471,368...235,475,204
Ensembl chr 1:235,471,298...235,475,204
JBrowse link
G Cyp3a18 cytochrome P450, family 3, subfamily a, polypeptide 18 increases expression ISO beta Carotene results in increased expression of CYP3A43 mRNA CTD PMID:17034753 NCBI chr12:8,880,528...8,930,382
Ensembl chr12:8,880,528...8,930,381
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 multiple interactions ISO beta Carotene promotes the reaction [[RXRA protein binds to NR1I2 protein] which results in increased expression of CYP3A4 mRNA] CTD PMID:16632523 NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Dhfr dihydrofolate reductase multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of DHFR mRNA CTD PMID:24657404 NCBI chr 2:23,585,876...23,611,199
Ensembl chr 2:23,586,031...23,613,713
JBrowse link
G Dlx2 distal-less homeobox 2 increases expression ISO beta Carotene results in increased expression of DLX2 mRNA CTD PMID:17034753 NCBI chr 3:56,371,347...56,373,230
Ensembl chr 3:56,370,483...56,373,597
JBrowse link
G Dlx4 distal-less homeobox 4 increases expression ISO beta Carotene results in increased expression of DLX4 mRNA CTD PMID:17034753 NCBI chr10:80,085,037...80,090,434
Ensembl chr10:80,085,465...80,090,456
JBrowse link
G Dtwd2 DTW domain containing 2 multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of DTWD2 mRNA CTD PMID:24657404 NCBI chr18:42,811,783...42,902,040
Ensembl chr18:42,816,681...42,901,832
JBrowse link
G Edn1 endothelin 1 multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of EDN1 mRNA CTD PMID:24657404 NCBI chr17:22,454,924...22,460,812
Ensembl chr17:22,454,420...22,460,885
JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2 subunit alpha multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of EIF2S1 mRNA CTD PMID:24657404 NCBI chr 6:97,672,829...97,697,499
Ensembl chr 6:97,672,766...97,706,225
JBrowse link
G Ercc2 ERCC excision repair 2, TFIIH core complex helicase subunit decreases expression ISO beta Carotene results in decreased expression of ERCC2 mRNA CTD PMID:17034753 NCBI chr 1:79,033,342...79,047,102
Ensembl chr 1:79,033,326...79,047,102
JBrowse link
G Esr1 estrogen receptor 1 multiple interactions ISO beta Carotene inhibits the reaction [Estradiol results in increased activity of ESR1 protein]; beta Carotene inhibits the reaction [Genistein results in increased activity of ESR1 protein]; beta Carotene inhibits the reaction [Paclitaxel results in increased expression of ESR1 mRNA] CTD PMID:17051425 PMID:19340624 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
JBrowse link
G Esr2 estrogen receptor 2 multiple interactions ISO beta Carotene inhibits the reaction [Estradiol results in increased activity of ESR2 protein]; beta Carotene inhibits the reaction [Genistein results in increased activity of ESR2 protein] CTD PMID:17051425 NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919
JBrowse link
G Fabp4 fatty acid binding protein 4 decreases expression ISO beta Carotene results in decreased expression of FABP4 mRNA CTD PMID:21569430 NCBI chr 2:91,580,858...91,585,578
Ensembl chr 2:91,580,885...91,585,578
JBrowse link
G Faim2 Fas apoptotic inhibitory molecule 2 increases expression ISO beta Carotene results in increased expression of FAIM2 mRNA CTD PMID:17034753 NCBI chr 7:130,632,368...130,659,353
Ensembl chr 7:130,633,348...130,659,168
JBrowse link
G Fas Fas cell surface death receptor increases expression ISO beta Carotene results in increased expression of FAS mRNA CTD PMID:17034753 NCBI chr 1:231,798,963...231,832,591
Ensembl chr 1:231,798,960...231,832,591
JBrowse link
G Fosl1 FOS like 1, AP-1 transcription factor subunit increases expression ISO beta Carotene results in increased expression of FOSL1 protein CTD PMID:20025956 NCBI chr 1:202,754,549...202,763,057
Ensembl chr 1:202,754,529...202,764,930
JBrowse link
G Foxa1 forkhead box A1 increases expression ISO beta Carotene results in increased expression of FOXA1 mRNA CTD PMID:17034753 NCBI chr 6:75,099,907...75,136,534
Ensembl chr 6:75,103,503...75,136,188
JBrowse link
G Foxm1 forkhead box M1 multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of FOXM1 mRNA CTD PMID:24657404 NCBI chr 4:161,639,561...161,652,012
Ensembl chr 4:161,638,816...161,650,684
JBrowse link
G Fzd6 frizzled class receptor 6 multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of FZD6 mRNA CTD PMID:24657404 NCBI chr 7:70,055,012...70,086,781
Ensembl chr 7:70,055,068...70,086,776
JBrowse link
G Gata6 GATA binding protein 6 increases expression ISO beta Carotene results in increased expression of GATA6 mRNA CTD PMID:17034753 NCBI chr18:2,188,121...2,219,532
Ensembl chr18:2,188,121...2,219,532
JBrowse link
G Gbp1 guanylate binding protein 1 increases expression ISO beta Carotene results in increased expression of GBP1 mRNA CTD PMID:17034753 NCBI chr 2:231,398,136...231,432,773
Ensembl chr 2:231,517,398...231,529,600
JBrowse link
G Gja1 gap junction protein, alpha 1 multiple interactions
increases expression
ISO
EXP
beta Carotene promotes the reaction [4-(2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1-propenyl)benzoic acid results in increased expression of GJA1 protein]; Ro 41-5253 inhibits the reaction [beta Carotene results in increased expression of GJA1 protein]
beta Carotene inhibits the reaction [Hydrogen Peroxide results in decreased expression of GJA1 mRNA]; beta Carotene inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of GJA1 protein]
CTD PMID:16091010 PMID:27154496 NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582
JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions ISO beta Carotene inhibits the reaction [arsenic trioxide results in decreased activity of GSR protein] CTD PMID:25542264 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
JBrowse link
G Gstk1 glutathione S-transferase kappa 1 decreases expression ISO beta Carotene results in decreased expression of GSTK1 mRNA CTD PMID:17034753 NCBI chr 4:71,118,979...71,123,298
Ensembl chr 4:71,118,896...71,123,292
JBrowse link
G Gstm2 glutathione S-transferase mu 2 increases expression ISO beta Carotene results in increased expression of GSTM2 mRNA CTD PMID:17034753 NCBI chr 2:195,624,015...195,628,774 JBrowse link
G Gstm3 glutathione S-transferase mu 3 increases expression ISO beta Carotene results in increased expression of GSTM5 mRNA CTD PMID:17034753 NCBI chr 2:195,590,450...195,612,578
Ensembl chr 2:195,607,289...195,612,475
JBrowse link
G Gstm4 glutathione S-transferase mu 4 decreases expression ISO beta Carotene results in decreased expression of GSTM4 mRNA CTD PMID:17034753 NCBI chr 2:195,667,940...195,685,315
Ensembl chr 2:195,680,004...195,685,323
JBrowse link
G Gstz1 glutathione S-transferase zeta 1 decreases expression ISO beta Carotene results in decreased expression of GSTZ1 mRNA CTD PMID:17034753 NCBI chr 6:106,794,594...106,805,284
Ensembl chr 6:106,794,074...106,805,284
JBrowse link
G Hoxa7 homeobox A7 increases expression ISO beta Carotene results in increased expression of HOXA7 mRNA CTD PMID:17034753 NCBI chr 4:81,315,730...81,317,629
Ensembl chr 4:81,314,625...81,317,659
JBrowse link
G Hoxb6 homeo box B6 increases expression ISO beta Carotene results in increased expression of HOXB6 mRNA CTD PMID:17034753 NCBI chr10:81,258,726...81,267,458
Ensembl chr10:81,265,056...81,267,449
JBrowse link
G Hoxc10 homeo box C10 increases expression ISO beta Carotene results in increased expression of HOXC10 mRNA CTD PMID:17034753 NCBI chr 7:134,103,741...134,108,966
Ensembl chr 7:134,103,643...134,108,966
JBrowse link
G Hprt1 hypoxanthine phosphoribosyltransferase 1 multiple interactions EXP beta Carotene inhibits the reaction [2-amino-1-methyl-6-phenylimidazo(4,5-b)pyridine results in increased mutagenesis of HPRT1 gene] CTD PMID:12467141 NCBI chr  X:132,736,175...132,768,149
Ensembl chr  X:132,736,096...132,768,154
JBrowse link
G Igfbp5 insulin-like growth factor binding protein 5 multiple interactions EXP [alpha-Tocopherol co-treated with beta Carotene co-treated with Ascorbic Acid co-treated with Zinc co-treated with Sodium Selenite] results in decreased expression of IGFBP5 mRNA CTD PMID:23859036 NCBI chr 9:74,452,371...74,464,953
Ensembl chr 9:74,448,382...74,465,156
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO beta Carotene promotes the reaction [Benzo(a)pyrene results in increased secretion of IL1B protein]; pyrazolanthrone inhibits the reaction [beta Carotene promotes the reaction [Benzo(a)pyrene results in increased secretion of IL1B protein]]; Quercetin inhibits the reaction [beta Carotene promotes the reaction [Benzo(a)pyrene results in increased secretion of IL1B protein]] CTD PMID:21447443 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Irf8 interferon regulatory factor 8 increases expression ISO beta Carotene results in increased expression of IRF8 mRNA CTD PMID:17034753 NCBI chr19:48,790,483...48,812,363
Ensembl chr19:48,790,588...48,811,829
JBrowse link
G Irx4 iroquois homeobox 4 decreases expression
multiple interactions
ISO beta Carotene results in decreased expression of IRX4 mRNA
[BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of IRX4 mRNA
CTD PMID:17034753 PMID:24657404 NCBI chr 1:30,030,561...30,039,549
Ensembl chr 1:30,030,561...30,039,549
JBrowse link
G Itgb1 integrin subunit beta 1 decreases expression ISO beta Carotene results in decreased expression of ITGB1 mRNA CTD PMID:17034753 NCBI chr19:56,705,123...56,753,199
Ensembl chr19:56,705,171...56,753,195
JBrowse link
G Itgb4 integrin subunit beta 4 decreases expression ISO beta Carotene results in decreased expression of ITGB4 mRNA CTD PMID:17034753 NCBI chr10:101,206,657...101,243,012
Ensembl chr10:101,206,665...101,243,012
JBrowse link
G Itm2a integral membrane protein 2A multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of ITM2A mRNA CTD PMID:24657404 NCBI chr  X:72,486,383...72,492,344
Ensembl chr  X:72,486,381...72,492,363
JBrowse link
G Ivl involucrin increases expression ISO beta Carotene results in increased expression of IVL mRNA CTD PMID:17034753 NCBI chr 2:178,146,694...178,160,807
Ensembl chr 2:178,147,061...178,149,100
JBrowse link
G Jun Jun proto-oncogene, AP-1 transcription factor subunit increases expression ISO beta Carotene results in increased expression of JUN protein CTD PMID:20025956 NCBI chr 5:109,894,175...109,897,268
Ensembl chr 5:109,893,145...109,897,656
JBrowse link
G Kif11 kinesin family member 11 multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of KIF11 mRNA CTD PMID:24657404 NCBI chr 1:235,124,371...235,176,760
Ensembl chr 1:235,124,316...235,176,766
JBrowse link
G Krt18 keratin 18 increases expression ISO beta Carotene results in increased expression of KRT18 mRNA CTD PMID:17034753 NCBI chr 7:133,157,486...133,161,162
Ensembl chr 7:133,157,475...133,161,166
JBrowse link
G Krt19 keratin 19 increases expression ISO beta Carotene results in increased expression of KRT19 mRNA CTD PMID:17034753 NCBI chr10:85,075,835...85,080,552 JBrowse link
G Krt2 keratin 2 increases expression ISO beta Carotene results in increased expression of KRT2 mRNA CTD PMID:17034753 NCBI chr 7:132,941,275...132,947,963
Ensembl chr 7:132,940,862...132,947,963
JBrowse link
G Krt7 keratin 7 affects expression ISO beta Carotene affects the expression of KRT7 mRNA CTD PMID:17034753 NCBI chr 7:132,528,863...132,545,052
Ensembl chr 7:132,528,895...132,545,052
JBrowse link
G Krt8 keratin 8 decreases expression ISO beta Carotene results in decreased expression of KRT8 mRNA CTD PMID:17034753 NCBI chr 7:133,124,203...133,131,656
Ensembl chr 7:133,124,203...133,131,728
JBrowse link
G Lancl1 LanC like 1 multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of LANCL1 mRNA CTD PMID:24657404 NCBI chr 9:68,515,052...68,548,646
Ensembl chr 9:68,518,574...68,548,628
JBrowse link
G Lhx3 LIM homeobox 3 increases expression ISO beta Carotene results in increased expression of LHX3 mRNA CTD PMID:17034753 NCBI chr 3:9,026,432...9,035,122
Ensembl chr 3:9,027,425...9,034,480
JBrowse link
G Lmnb2 lamin B2 multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of LMNB2 mRNA CTD PMID:24657404 NCBI chr 7:8,792,628...8,808,665
Ensembl chr 7:8,789,314...8,808,665
JBrowse link
G Lpl lipoprotein lipase decreases expression ISO beta Carotene results in decreased expression of LPL mRNA CTD PMID:21569430 NCBI chr16:20,830,055...20,853,855
Ensembl chr16:20,829,465...20,855,249
JBrowse link
G Mapk1 mitogen activated protein kinase 1 increases phosphorylation
multiple interactions
ISO
EXP
beta Carotene results in increased phosphorylation of MAPK1 protein
beta Carotene inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK1 protein]
CTD PMID:16206275 PMID:27154496 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 increases phosphorylation
multiple interactions
ISO
EXP
beta Carotene results in increased phosphorylation of MAPK3 protein
beta Carotene inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK3 protein]
CTD PMID:16206275 PMID:27154496 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mbl2 mannose binding lectin 2 multiple interactions ISO MBL2 gene polymorphism affects the susceptibility to [Vitamin A co-treated with beta Carotene] CTD PMID:16960176 NCBI chr 1:228,016,439...228,024,736 JBrowse link
G Mcl1 MCL1 apoptosis regulator, BCL2 family member affects expression ISO beta Carotene affects the expression of MCL1 mRNA CTD PMID:17034753 NCBI chr 2:183,219,137...183,235,676
Ensembl chr 2:183,219,220...183,222,303
JBrowse link
G Meis2 Meis homeobox 2 increases expression ISO beta Carotene results in increased expression of MEIS2 mRNA CTD PMID:17034753 NCBI chr 3:102,742,905...102,944,833
Ensembl chr 3:102,742,900...102,949,696
JBrowse link
G Meox1 mesenchyme homeobox 1 increases expression ISO beta Carotene results in increased expression of MEOX1 mRNA CTD PMID:17034753 NCBI chr10:86,818,450...86,837,563
Ensembl chr10:86,818,478...86,837,660
JBrowse link
G Mettl21a methyltransferase like 21A multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of METTL21A mRNA CTD PMID:24657404 NCBI chr 9:65,934,253...65,999,964
Ensembl chr 9:65,978,051...65,987,550
JBrowse link
G Mettl9 methyltransferase like 9 multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of METTL9 mRNA CTD PMID:24657404 NCBI chr 1:175,575,805...175,623,065
Ensembl chr 1:175,577,890...175,623,061
JBrowse link
G Mgmt O-6-methylguanine-DNA methyltransferase affects response to substance ISO MGMT gene SNP affects the susceptibility to beta Carotene CTD PMID:16014702 NCBI chr 1:191,710,980...191,937,760
Ensembl chr 1:191,710,930...191,937,756
JBrowse link
G Mki67 marker of proliferation Ki-67 multiple interactions EXP [alpha-Tocopherol co-treated with beta Carotene co-treated with Ascorbic Acid co-treated with Zinc co-treated with Sodium Selenite] results in decreased expression of MKI67 mRNA CTD PMID:23859036 NCBI chr 1:190,496,319...190,522,983
Ensembl chr 1:190,496,319...190,522,762
JBrowse link
G Mnx1 motor neuron and pancreas homeobox 1 increases expression ISO beta Carotene results in increased expression of MNX1 mRNA CTD PMID:17034753 NCBI chr 4:5,866,506...5,871,465
Ensembl chr 4:5,866,506...5,871,465
JBrowse link
G Mpo myeloperoxidase multiple interactions EXP [Ascorbic Acid co-treated with beta Carotene co-treated with alpha-Tocopherol co-treated with Sodium Selenite] inhibits the reaction [Galactosamine results in increased activity of MPO protein] CTD PMID:31022331 NCBI chr10:72,594,458...72,608,862
Ensembl chr10:72,594,661...72,604,819
JBrowse link
G Mrpl57 mitochondrial ribosomal protein L57 multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of MRPL57 mRNA CTD PMID:24657404 NCBI chr15:31,970,904...31,971,766
Ensembl chr15:31,970,860...31,973,993
JBrowse link
G Msh5 mutS homolog 5 increases expression ISO beta Carotene results in increased expression of MSH5 mRNA CTD PMID:17034753 NCBI chr20:3,773,867...3,793,337
Ensembl chr20:3,776,942...3,793,336
JBrowse link
G Mtch2 mitochondrial carrier 2 multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of MTCH2 mRNA CTD PMID:24657404 NCBI chr 3:76,830,549...76,850,189
Ensembl chr 3:76,830,413...76,850,189
JBrowse link
G Muc5ac mucin 5AC, oligomeric mucus/gel-forming increases expression ISO beta Carotene results in increased expression of MUC5AC mRNA CTD PMID:17034753 NCBI chr 1:196,864,375...196,896,475 JBrowse link
G Nckap1 NCK-associated protein 1 multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of NCKAP1 mRNA CTD PMID:24657404 NCBI chr 3:65,417,450...65,491,769
Ensembl chr 3:65,417,453...65,492,217
JBrowse link
G Nom1 nucleolar protein with MIF4G domain 1 multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of NOM1 mRNA CTD PMID:24657404 NCBI chr 4:5,891,220...5,910,741
Ensembl chr 4:5,892,909...5,909,709
JBrowse link
G Nos1 nitric oxide synthase 1 increases expression ISO beta Carotene results in increased expression of NOS1 mRNA CTD PMID:17034753 NCBI chr12:38,615,111...38,795,492
Ensembl chr12:38,626,714...38,710,945
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions EXP [Ascorbic Acid co-treated with Vitamin E co-treated with beta Carotene co-treated with Copper] inhibits the reaction [Streptozocin results in increased expression of NOS2 mRNA] CTD PMID:18779489 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Nr1i2 nuclear receptor subfamily 1, group I, member 2 multiple interactions
increases activity
ISO beta Carotene promotes the reaction [[RXRA protein binds to NR1I2 protein] which results in increased expression of CYP3A4 mRNA]
beta Carotene results in increased activity of NR1I2 protein
CTD PMID:15949683 PMID:16632523 NCBI chr11:62,460,213...62,496,665
Ensembl chr11:62,460,213...62,496,658
JBrowse link
G Olr1 oxidized low density lipoprotein receptor 1 increases expression ISO beta Carotene results in increased expression of OLR1 mRNA CTD PMID:17034753 NCBI chr 4:162,926,436...162,949,057
Ensembl chr 4:162,926,439...162,948,523
JBrowse link
G Pard6a par-6 family cell polarity regulator alpha multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of PARD6A mRNA CTD PMID:24657404 NCBI chr19:33,589,583...33,591,900
Ensembl chr19:33,589,542...33,591,900
JBrowse link
G Pcdh1 protocadherin 1 multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of PCDH1 mRNA CTD PMID:24657404 NCBI chr18:30,011,692...30,039,679
Ensembl chr18:30,013,185...30,039,318
JBrowse link
G Pcdhgc3 protocadherin gamma subfamily C, 3 increases expression ISO beta Carotene results in increased expression of PCDHGC3 mRNA CTD PMID:17034753 NCBI chr18:29,633,016...29,667,865 JBrowse link
G Pdgfrb platelet derived growth factor receptor beta multiple interactions EXP [alpha-Tocopherol co-treated with beta Carotene co-treated with Ascorbic Acid co-treated with Zinc co-treated with Sodium Selenite] results in decreased expression of PDGFRB mRNA; [alpha-Tocopherol co-treated with beta Carotene co-treated with Ascorbic Acid co-treated with Zinc co-treated with Sodium Selenite] results in decreased expression of PDGFRB protein CTD PMID:23859036 NCBI chr18:54,500,002...54,538,843
Ensembl chr18:54,499,964...54,538,843
JBrowse link
G Pik3r5 phosphoinositide-3-kinase, regulatory subunit 5 increases expression ISO beta Carotene results in increased expression of PIK3R5 protein CTD PMID:20025956 NCBI chr10:53,132,585...53,200,663
Ensembl chr10:53,132,603...53,199,374
JBrowse link
G Plat plasminogen activator, tissue type multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of PLAT mRNA CTD PMID:24657404 NCBI chr16:69,240,582...69,265,177
Ensembl chr16:69,240,585...69,268,223
JBrowse link
G Plscr1 phospholipid scramblase 1 increases expression ISO beta Carotene results in increased expression of PLSCR1 mRNA CTD PMID:17034753 NCBI chr 8:92,784,279...92,804,698
Ensembl chr 8:92,784,356...92,804,692
JBrowse link
G Plscr3 phospholipid scramblase 3 increases expression ISO beta Carotene results in increased expression of PLSCR3 mRNA CTD PMID:17034753 NCBI chr10:54,566,556...54,573,240
Ensembl chr10:54,566,873...54,578,709
JBrowse link
G Plscr4 phospholipid scramblase 4 increases expression ISO beta Carotene results in increased expression of PLSCR4 mRNA CTD PMID:17034753 NCBI chr 8:92,987,290...93,026,056
Ensembl chr 8:92,987,381...93,026,049
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha decreases expression ISO beta Carotene results in decreased expression of PPARA mRNA CTD PMID:21569430 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma decreases expression ISO beta Carotene results in decreased expression of PPARG mRNA CTD PMID:21569430 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Rad51ap1 RAD51 associated protein 1 decreases expression ISO beta Carotene results in decreased expression of RAD51AP1 mRNA CTD PMID:17034753 NCBI chr 4:159,759,454...159,772,524
Ensembl chr 4:159,759,459...159,772,524
JBrowse link
G Rad51d RAD51 paralog D increases expression ISO beta Carotene results in increased expression of RAD51D mRNA CTD PMID:17034753 NCBI chr10:67,805,720...67,824,452 JBrowse link
G Rara retinoic acid receptor, alpha decreases expression ISO beta Carotene results in decreased expression of RARA mRNA CTD PMID:17034753 NCBI chr10:83,883,490...83,928,932
Ensembl chr10:83,893,384...83,928,142
JBrowse link
G Rarb retinoic acid receptor, beta increases expression ISO beta Carotene results in increased expression of RARB mRNA CTD PMID:17034753 NCBI chr15:8,700,533...9,051,288
Ensembl chr15:8,406,492...9,051,288
JBrowse link
G Rarres1 retinoic acid receptor responder 1 increases expression ISO beta Carotene results in increased expression of RARRES1 mRNA CTD PMID:17034753 NCBI chr 2:151,749,715...151,783,975
Ensembl chr 2:151,749,715...151,783,978
JBrowse link
G Rbp4 retinol binding protein 4 multiple interactions ISO beta Carotene results in decreased expression of and results in decreased secretion of RBP4 protein CTD PMID:22542753 NCBI chr 1:235,893,917...235,901,315
Ensembl chr 1:235,893,917...235,901,399
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit decreases phosphorylation ISO beta Carotene results in decreased phosphorylation of RELA protein CTD PMID:26733226 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Rpp14 ribonuclease P/MRP subunit p14 multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of RPP14 mRNA CTD PMID:24657404 NCBI chr15:16,837,796...16,847,970
Ensembl chr15:16,837,743...16,847,765
JBrowse link
G Rrm1 ribonucleotide reductase catalytic subunit M1 multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of RRM1 mRNA CTD PMID:24657404 NCBI chr 1:156,823,960...156,848,262
Ensembl chr 1:156,823,960...156,848,261
JBrowse link
G Rxra retinoid X receptor alpha multiple interactions ISO beta Carotene promotes the reaction [[RXRA protein binds to NR1I2 protein] which results in increased expression of CYP3A4 mRNA] CTD PMID:16632523 NCBI chr 3:10,989,832...11,076,366
Ensembl chr 3:10,989,832...11,073,712
JBrowse link
G Scarb1 scavenger receptor class B, member 1 increases transport ISO SCARB1 protein results in increased transport of beta Carotene CTD PMID:16177187 NCBI chr12:31,296,143...31,362,649
Ensembl chr12:31,296,156...31,362,647
JBrowse link
G Six6 SIX homeobox 6 increases expression ISO beta Carotene results in increased expression of SIX6 mRNA CTD PMID:17034753 NCBI chr 6:91,634,568...91,639,548
Ensembl chr 6:91,634,568...91,639,548
JBrowse link
G Slc2a4 solute carrier family 2 member 4 decreases expression ISO beta Carotene results in decreased expression of SLC2A4 mRNA CTD PMID:21569430 NCBI chr10:54,666,015...54,671,581
Ensembl chr10:54,666,015...54,671,565
JBrowse link
G Sod1 superoxide dismutase 1 decreases expression ISO beta Carotene results in decreased expression of SOD1 mRNA CTD PMID:17034753 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions EXP [alpha-Tocopherol co-treated with beta Carotene co-treated with Ascorbic Acid co-treated with Zinc co-treated with Sodium Selenite] results in decreased expression of SOD2 mRNA; [Ascorbic Acid co-treated with Vitamin E co-treated with beta Carotene co-treated with Copper] inhibits the reaction [Streptozocin results in decreased expression of SOD2 mRNA]; [Ascorbic Acid co-treated with Vitamin E co-treated with beta Carotene co-treated with Copper] inhibits the reaction [Streptozocin results in decreased expression of SOD2 protein] CTD PMID:18779489 PMID:23859036 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
JBrowse link
G Sptlc2 serine palmitoyltransferase, long chain base subunit 2 affects expression ISO beta Carotene affects the expression of SPTLC2 mRNA CTD PMID:17034753 NCBI chr 6:106,948,681...107,031,584
Ensembl chr 6:106,950,949...107,031,542
JBrowse link
G Srebf1 sterol regulatory element binding transcription factor 1 increases expression ISO beta Carotene results in increased expression of SREBF1 mRNA CTD PMID:17034753 NCBI chr10:45,007,637...45,029,650
Ensembl chr10:45,007,637...45,029,650
JBrowse link
G Tfcp2 transcription factor CP2 multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of TFCP2 mRNA CTD PMID:24657404 NCBI chr 7:131,616,777...131,658,995
Ensembl chr 7:131,616,785...131,658,939
JBrowse link
G Tgm2 transglutaminase 2 increases expression ISO beta Carotene results in increased expression of TGM2 mRNA CTD PMID:17034753 NCBI chr 3:146,772,684...146,801,924
Ensembl chr 3:146,772,687...146,801,981
JBrowse link
G Tgm4 transglutaminase 4 increases expression ISO beta Carotene results in increased expression of TGM4 mRNA CTD PMID:17034753 NCBI chr 8:122,689,429...122,726,463
Ensembl chr 8:122,689,429...122,726,463
JBrowse link
G Thoc7 THO complex 7 multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of THOC7 mRNA CTD PMID:24657404 NCBI chr15:11,262,362...11,277,200
Ensembl chr15:11,262,613...11,277,193
JBrowse link
G Tmem209 transmembrane protein 209 multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of TMEM209 mRNA CTD PMID:24657404 NCBI chr 4:59,101,656...59,128,687
Ensembl chr 4:59,101,550...59,128,630
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO beta Carotene affects the reaction [Tetradecanoylphorbol Acetate results in increased secretion of TNF protein]; beta Carotene promotes the reaction [Benzo(a)pyrene results in increased secretion of TNF protein]; pyrazolanthrone inhibits the reaction [beta Carotene promotes the reaction [Benzo(a)pyrene results in increased secretion of TNF protein]]; Quercetin affects the reaction [beta Carotene affects the reaction [Tetradecanoylphorbol Acetate results in increased secretion of TNF protein]]; Quercetin inhibits the reaction [beta Carotene promotes the reaction [Benzo(a)pyrene results in increased secretion of TNF protein]]
beta Carotene promotes the reaction [Lipopolysaccharides results in increased secretion of TNF protein]
CTD PMID:19135038 PMID:21447443 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tnfrsf9 TNF receptor superfamily member 9 increases expression ISO beta Carotene results in increased expression of TNFRSF9 mRNA CTD PMID:17034753 NCBI chr 5:161,381,662...161,408,003
Ensembl chr 5:161,381,662...161,408,000
JBrowse link
G Tnfsf10 TNF superfamily member 10 increases expression ISO beta Carotene results in increased expression of TNFSF10 mRNA CTD PMID:17034753 NCBI chr 2:110,199,835...110,227,239
Ensembl chr 2:110,207,916...110,225,135
JBrowse link
G Ttc21b tetratricopeptide repeat domain 21B multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of TTC21B mRNA CTD PMID:24657404 NCBI chr 3:50,861,367...50,935,782
Ensembl chr 3:50,861,367...50,935,903
JBrowse link
G Twf1 twinfilin actin-binding protein 1 multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of TWF1 mRNA CTD PMID:24657404 NCBI chr 7:125,715,938...125,727,834
Ensembl chr 7:125,716,015...125,727,894
JBrowse link
G Txndc9 thioredoxin domain containing 9 increases expression ISO beta Carotene results in increased expression of TXNDC9 mRNA CTD PMID:17034753 NCBI chr 9:40,211,818...40,221,953
Ensembl chr 9:40,211,412...40,384,279
JBrowse link
G Tymp thymidine phosphorylase multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of TYMP mRNA CTD PMID:24657404 NCBI chr 7:120,438,768...120,444,088
Ensembl chr 7:120,438,770...120,443,874
Ensembl chr 7:120,438,770...120,443,874
JBrowse link
G Xrcc3 X-ray repair cross complementing 3 increases expression ISO beta Carotene results in increased expression of XRCC3 mRNA CTD PMID:17034753 NCBI chr 6:130,863,405...130,873,765
Ensembl chr 6:130,863,959...130,872,444
JBrowse link
G Ythdc2 YTH domain containing 2 multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of YTHDC2 mRNA CTD PMID:24657404 NCBI chr18:37,266,559...37,331,681
Ensembl chr18:37,265,836...37,331,023
JBrowse link
G Zdhhc3 zinc finger DHHC-type palmitoyltransferase 3 multiple interactions ISO [BCO1 protein affects the susceptibility to beta Carotene] which affects the expression of ZDHHC3 mRNA CTD PMID:24657404 NCBI chr 8:122,725,206...122,773,519
Ensembl chr 8:122,715,111...122,773,529
JBrowse link
bixin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Nfe2l2 NFE2 like bZIP transcription factor 2 decreases ubiquitination ISO bixin results in decreased ubiquitination of NFE2L2 protein CTD PMID:30698894 NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
canthaxanthin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 increases expression ISO
EXP
Canthaxanthin results in increased expression of CYP1A1 mRNA CTD PMID:9271336 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 increases expression EXP
ISO
Canthaxanthin results in increased expression of CYP1A2 mRNA CTD PMID:9271336 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
capsanthin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gja1 gap junction protein, alpha 1 multiple interactions EXP capsanthin inhibits the reaction [Hydrogen Peroxide results in decreased expression of GJA1 mRNA]; capsanthin inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of GJA1 protein] CTD PMID:27154496 NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions EXP capsanthin inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK1 protein] CTD PMID:27154496 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions EXP capsanthin inhibits the reaction [Hydrogen Peroxide results in increased phosphorylation of MAPK3 protein] CTD PMID:27154496 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
carotenoid term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bco2 beta-carotene oxygenase 2 decreases metabolic processing
multiple interactions
ISO BCO2 gene mutant form results in decreased metabolism of Carotenoids
[[BCO2 gene mutant form results in decreased metabolism of Carotenoids] which results in increased abundance of Carotenoids] which results in increased expression of SOD2 protein; [BCO2 gene mutant form results in decreased metabolism of Carotenoids] which results in increased abundance of Carotenoids; BCO2 protein results in increased oxidation of and results in increased cleavage of Carotenoids
CTD PMID:21106934 NCBI chr 8:50,882,174...50,907,676
Ensembl chr 8:50,882,181...50,915,467
JBrowse link
G Cat catalase increases activity ISO Carotenoids results in increased activity of CAT protein CTD PMID:29205955 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 affects response to substance ISO CYP1A2 protein polymorphism affects the susceptibility to Carotenoids CTD PMID:15095308 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
G Nat1 N-acetyltransferase 1 affects response to substance ISO NAT1 protein polymorphism affects the susceptibility to Carotenoids CTD PMID:15095308 NCBI chr16:22,218,217...22,238,516 JBrowse link
G Nat2 N-acetyltransferase 2 affects response to substance ISO NAT2 protein polymorphism affects the susceptibility to Carotenoids CTD PMID:15095308 NCBI chr16:22,207,362...22,238,513
Ensembl chr16:22,208,194...22,238,520
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma decreases expression ISO Carotenoids results in decreased expression of PPARG mRNA CTD PMID:11237167 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Rarg retinoic acid receptor, gamma increases expression ISO Carotenoids results in increased expression of RARG mRNA CTD PMID:11237167 NCBI chr 7:133,367,833...133,390,301
Ensembl chr 7:133,367,833...133,390,177
JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions
increases expression
ISO [[BCO2 gene mutant form results in decreased metabolism of Carotenoids] which results in increased abundance of Carotenoids] which results in increased expression of SOD2 protein
Carotenoids results in increased expression of SOD2 protein
CTD PMID:21106934 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
JBrowse link
crocin-1 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acp5 acid phosphatase 5, tartrate resistant multiple interactions ISO crocin promotes the reaction [pyrazolanthrone inhibits the reaction [TNFSF11 protein results in increased activity of ACP5 protein]] CTD PMID:30580027 NCBI chr 8:20,663,984...20,670,604
Ensembl chr 8:20,663,985...20,667,929
JBrowse link
G Akt2 AKT serine/threonine kinase 2 multiple interactions ISO crocin inhibits the reaction [[TNFSF11 protein co-treated with pyrazolanthrone] results in increased expression of AKT2 mRNA] CTD PMID:30580027 NCBI chr 1:82,877,228...82,933,828
Ensembl chr 1:82,883,547...82,933,817
JBrowse link
G Bambi BMP and activin membrane-bound inhibitor multiple interactions EXP crocin inhibits the reaction [Cisplatin results in decreased expression of BAMBI mRNA] CTD PMID:32259551 NCBI chr17:54,121,251...54,125,816
Ensembl chr17:54,121,255...54,126,060
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions
increases expression
EXP
ISO
crocin inhibits the reaction [Arsenic Trioxide results in increased expression of BAX mRNA]; crocin inhibits the reaction [Arsenic Trioxide results in increased expression of BAX protein]; crocin inhibits the reaction [Diazinon results in increased expression of BAX mRNA]; crocin inhibits the reaction [Diazinon results in increased expression of BAX protein]
crocin results in increased expression of BAX mRNA
CTD PMID:23523949 PMID:27353299 PMID:32886819 PMID:32920515 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions
decreases expression
ISO
EXP
[crocin co-treated with Paraquat] results in decreased expression of BCL2 mRNA
crocin inhibits the reaction [Arsenic Trioxide results in decreased expression of BCL2 mRNA]; crocin inhibits the reaction [Arsenic Trioxide results in decreased expression of BCL2 protein]
crocin results in decreased expression of BCL2 mRNA
CTD PMID:31911963 PMID:32886819 PMID:32920515 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Bdnf brain-derived neurotrophic factor increases expression EXP crocin results in increased expression of BDNF mRNA; crocin results in increased expression of BDNF protein CTD PMID:24401376 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615
JBrowse link
G Birc5 baculoviral IAP repeat-containing 5 decreases expression ISO crocin results in decreased expression of BIRC5 mRNA CTD PMID:32886819 NCBI chr10:103,072,530...103,081,382
Ensembl chr10:103,073,408...103,081,380
JBrowse link
G Casp3 caspase 3 multiple interactions
increases expression
increases cleavage
EXP
ISO
crocin affects the reaction [Ethanol results in increased expression of CASP3 mRNA]; crocin inhibits the reaction [Arsenic Trioxide results in increased expression of CASP3 mRNA]; crocin inhibits the reaction [Arsenic Trioxide results in increased expression of CASP3 protein]; crocin inhibits the reaction [Carbon Tetrachloride results in increased activity of CASP3 protein]; crocin inhibits the reaction [Diazinon results in increased activity of CASP3 protein]; crocin inhibits the reaction [Diazinon results in increased cleavage of CASP3 protein]; crocin inhibits the reaction [Diazinon results in increased expression of CASP3 protein modified form]; crocin inhibits the reaction [Doxorubicin results in increased activity of CASP3 protein]; crocin inhibits the reaction [Ethanol results in increased activity of CASP3 protein]
crocin results in increased expression of CASP3 mRNA
crocin inhibits the reaction [Paraquat results in increased expression of CASP3 mRNA]
MYCN protein inhibits the reaction [crocin results in increased cleavage of CASP3 protein]
CTD PMID:23523949 PMID:25637687 PMID:25899501 PMID:26807765 PMID:27353299 More... NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp8 caspase 8 increases activity ISO crocin results in increased activity of CASP8 protein CTD PMID:32886819 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Casp9 caspase 9 multiple interactions
increases activity
EXP
ISO
crocin inhibits the reaction [Diazinon results in increased cleavage of CASP9 protein]
crocin results in increased activity of CASP9 protein
CTD PMID:27353299 PMID:32886819 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Cat catalase multiple interactions
decreases activity
increases activity
EXP
ISO
crocin inhibits the reaction [Arsenic Trioxide results in decreased activity of CAT protein]; crocin inhibits the reaction [Carbon Tetrachloride results in decreased activity of CAT protein]; crocin inhibits the reaction [Streptozocin results in decreased activity of CAT protein]
crocin results in decreased activity of CAT protein
crocin inhibits the reaction [Patulin results in increased activity of CAT protein]
crocin results in increased activity of CAT protein
CTD PMID:25899501 PMID:26584762 PMID:29409856 PMID:32886819 PMID:32920515 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Ccnd1 cyclin D1 decreases expression ISO crocin results in decreased expression of CCND1 mRNA CTD PMID:32886819 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Ckm creatine kinase, M-type multiple interactions EXP crocin inhibits the reaction [Diazinon results in increased activity of CKM protein] CTD PMID:23523949 NCBI chr 1:79,061,390...79,071,721
Ensembl chr 1:79,061,456...79,071,720
JBrowse link
G Col2a1 collagen type II alpha 1 chain multiple interactions EXP [geniposide co-treated with phellodendrine co-treated with magnoflorine co-treated with Chlorogenic Acid co-treated with crocin co-treated with Flavonoids co-treated with Berberine Alkaloids] inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in decreased abundance of Amino Acids]; [geniposide co-treated with phellodendrine co-treated with magnoflorine co-treated with Chlorogenic Acid co-treated with crocin co-treated with Flavonoids co-treated with Berberine Alkaloids] inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in decreased abundance of Pantothenic Acid]; [geniposide co-treated with phellodendrine co-treated with magnoflorine co-treated with Chlorogenic Acid co-treated with crocin co-treated with Flavonoids co-treated with Berberine Alkaloids] inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in decreased abundance of phenylpyruvic acid]; [geniposide co-treated with phellodendrine co-treated with magnoflorine co-treated with Chlorogenic Acid co-treated with crocin co-treated with Flavonoids co-treated with Berberine Alkaloids] inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in increased abundance of Allantoin]; [geniposide co-treated with phellodendrine co-treated with magnoflorine co-treated with Chlorogenic Acid co-treated with crocin co-treated with Flavonoids co-treated with Berberine Alkaloids] inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in increased abundance of Amino Acids]; [geniposide co-treated with phellodendrine co-treated with magnoflorine co-treated with Chlorogenic Acid co-treated with crocin co-treated with Flavonoids co-treated with Berberine Alkaloids] inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in increased abundance of Carnitine]; [geniposide co-treated with phellodendrine co-treated with magnoflorine co-treated with Chlorogenic Acid co-treated with crocin co-treated with Flavonoids co-treated with Berberine Alkaloids] inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in increased abundance of Citric Acid]; [geniposide co-treated with phellodendrine co-treated with magnoflorine co-treated with Chlorogenic Acid co-treated with crocin co-treated with Flavonoids co-treated with Berberine Alkaloids] inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in increased abundance of Creatine]; [geniposide co-treated with phellodendrine co-treated with magnoflorine co-treated with Chlorogenic Acid co-treated with crocin co-treated with Flavonoids co-treated with Berberine Alkaloids] inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in increased abundance of Creatinine]; [geniposide co-treated with phellodendrine co-treated with magnoflorine co-treated with Chlorogenic Acid co-treated with crocin co-treated with Flavonoids co-treated with Berberine Alkaloids] inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in increased abundance of phenylacetylglycine]; [geniposide co-treated with phellodendrine co-treated with magnoflorine co-treated with Chlorogenic Acid co-treated with crocin co-treated with Flavonoids co-treated with Berberine Alkaloids] inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in increased abundance of Succinic Acid]; [geniposide co-treated with phellodendrine co-treated with magnoflorine co-treated with Chlorogenic Acid co-treated with crocin co-treated with Flavonoids co-treated with Berberine Alkaloids] inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in increased abundance of Uric Acid]; [geniposide co-treated with phellodendrine co-treated with magnoflorine co-treated with Chlorogenic Acid co-treated with crocin co-treated with Flavonoids co-treated with Berberine Alkaloids] inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in increased abundance of Uridine]; [geniposide co-treated with phellodendrine co-treated with magnoflorine co-treated with Chlorogenic Acid co-treated with crocin co-treated with Flavonoids co-treated with Berberine Alkaloids] inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in increased secretion of IL1B protein] CTD PMID:24709313 NCBI chr 7:129,098,489...129,127,620
Ensembl chr 7:129,098,786...129,127,546
JBrowse link
G Creb1 cAMP responsive element binding protein 1 multiple interactions EXP crocin results in increased expression of and results in increased phosphorylation of CREB1 protein CTD PMID:24401376 NCBI chr 9:65,903,511...65,972,562
Ensembl chr 9:65,903,547...65,970,816
JBrowse link
G Cycs cytochrome c, somatic multiple interactions EXP crocin inhibits the reaction [Diazinon affects the localization of CYCS protein] CTD PMID:23523949 NCBI chr 4:79,651,894...79,653,994
Ensembl chr 4:79,651,378...79,654,054
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions
decreases activity
EXP crocin inhibits the reaction [Carbon Tetrachloride results in increased activity of CYP2E1 protein]
crocin results in decreased activity of CYP2E1 protein
CTD PMID:25899501 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
JBrowse link
G Glo1 glyoxalase 1 multiple interactions ISO crocin inhibits the reaction [[TNFSF11 protein co-treated with Pyruvaldehyde] results in decreased activity of GLO1 protein] CTD PMID:30580027 NCBI chr20:8,663,617...8,681,661
Ensembl chr20:8,662,801...8,681,649
JBrowse link
G Gpt glutamic--pyruvic transaminase multiple interactions EXP crocin inhibits the reaction [Cisplatin results in increased activity of GPT protein] CTD PMID:32259551 NCBI chr 7:108,416,646...108,419,495
Ensembl chr 7:108,416,642...108,419,494
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions EXP crocin inhibits the reaction [Arsenic Trioxide results in decreased expression of HMOX1 protein] CTD PMID:32920515 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hspa1l heat shock protein family A (Hsp70) member 1 like multiple interactions EXP crocin inhibits the reaction [Ethanol results in increased expression of HSPA1L mRNA] CTD PMID:25637687 NCBI chr20:3,848,843...3,855,571
Ensembl chr20:3,848,843...3,855,571
JBrowse link
G Il10 interleukin 10 multiple interactions EXP crocin inhibits the reaction [Doxorubicin results in decreased expression of IL10 protein] CTD PMID:26807765 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313
JBrowse link
G Il1b interleukin 1 beta multiple interactions EXP [geniposide co-treated with phellodendrine co-treated with magnoflorine co-treated with Chlorogenic Acid co-treated with crocin co-treated with Flavonoids co-treated with Berberine Alkaloids] inhibits the reaction [[COL2A1 protein co-treated with Freund's Adjuvant] results in increased secretion of IL1B protein]; crocin inhibits the reaction [Doxorubicin results in increased expression of IL1B protein] CTD PMID:24709313 PMID:26807765 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il6 interleukin 6 multiple interactions
decreases expression
EXP
ISO
crocin inhibits the reaction [Arsenic Trioxide results in increased expression of IL6 mRNA]; crocin inhibits the reaction [Arsenic Trioxide results in increased expression of IL6 protein]; crocin inhibits the reaction [Carbon Tetrachloride results in increased expression of IL6 protein]; crocin inhibits the reaction [Ethanol results in decreased expression of IL6 protein]; crocin inhibits the reaction [Streptozocin results in increased expression of IL6 protein]
crocin results in decreased expression of IL6 mRNA
CTD PMID:25637687 PMID:25899501 PMID:29409856 PMID:32886819 PMID:32920515 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Jak2 Janus kinase 2 multiple interactions ISO crocin affects the expression of and affects the phosphorylation of JAK2 protein CTD PMID:32886819 NCBI chr 1:226,995,334...227,054,381
Ensembl chr 1:226,995,334...227,054,189
JBrowse link
G Keap1 Kelch-like ECH-associated protein 1 multiple interactions EXP crocin inhibits the reaction [Arsenic Trioxide results in decreased expression of KEAP1 protein] CTD PMID:32920515 NCBI chr 8:19,768,375...19,777,862
Ensembl chr 8:19,768,375...19,777,862
JBrowse link
G Ldlr low density lipoprotein receptor multiple interactions EXP crocin inhibits the reaction [Diazinon results in decreased expression of LDLR mRNA] CTD PMID:24132704 NCBI chr 8:20,270,020...20,292,981
Ensembl chr 8:20,270,041...20,294,580
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions
decreases phosphorylation
EXP
ISO
crocin inhibits the reaction [bisphenol A results in increased phosphorylation of MAPK1 protein]; crocin inhibits the reaction [Diazinon results in decreased phosphorylation of MAPK1 protein]
crocin results in decreased phosphorylation of MAPK1 protein
CTD PMID:24132704 PMID:28689058 PMID:32886819 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions
decreases phosphorylation
EXP
ISO
crocin inhibits the reaction [bisphenol A results in increased phosphorylation of MAPK3 protein]; crocin inhibits the reaction [Diazinon results in decreased phosphorylation of MAPK3 protein]
crocin results in decreased phosphorylation of MAPK3 protein
crocin inhibits the reaction [[TNFSF11 protein co-treated with pyrazolanthrone] results in increased expression of MAPK3 mRNA]
CTD PMID:24132704 PMID:28689058 PMID:30580027 PMID:32886819 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mir122 microRNA 122 multiple interactions EXP crocin inhibits the reaction [bisphenol A results in increased expression of MIR122 mRNA] CTD PMID:28689058 NCBI chr18:58,758,703...58,758,787 JBrowse link
G Mir29b1 microRNA 29b-1 increases expression
multiple interactions
EXP crocin results in increased expression of MIR29B1 mRNA
Cisplatin inhibits the reaction [crocin results in increased expression of MIR29B1 mRNA]; crocin inhibits the reaction [Cisplatin results in decreased expression of MIR29B1 mRNA]
CTD PMID:32259551 NCBI chr 4:59,650,987...59,651,067
Ensembl chr 4:59,650,986...59,651,067
JBrowse link
G Mpo myeloperoxidase multiple interactions EXP crocin inhibits the reaction [Ethanol results in increased activity of MPO protein] CTD PMID:25637687 NCBI chr10:72,594,458...72,608,862
Ensembl chr10:72,594,661...72,604,819
JBrowse link
G Myc MYC proto-oncogene, bHLH transcription factor decreases expression ISO crocin results in decreased expression of MYC mRNA CTD PMID:32886819 NCBI chr 7:93,593,705...93,598,633
Ensembl chr 7:93,593,705...93,598,630
JBrowse link
G Mycn MYCN proto-oncogene, bHLH transcription factor decreases response to substance
multiple interactions
decreases expression
ISO MYCN results in decreased susceptibility to crocin
crocin results in decreased expression of and results in decreased stability of MYCN mRNA; MYCN protein inhibits the reaction [crocin results in increased cleavage of CASP3 protein]; MYCN protein inhibits the reaction [crocin results in increased cleavage of PARP1 protein]
crocin results in decreased expression of MYCN protein
CTD PMID:30672053 NCBI chr 6:35,717,764...35,723,590
Ensembl chr 6:35,717,764...35,723,590
JBrowse link
G Myd88 MYD88, innate immune signal transduction adaptor multiple interactions EXP crocin inhibits the reaction [Cisplatin results in increased expression of MYD88 mRNA]; crocin inhibits the reaction [Cisplatin results in increased expression of MYD88 protein] CTD PMID:32259551 NCBI chr 8:119,074,439...119,078,508
Ensembl chr 8:119,074,437...119,079,415
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions EXP crocin inhibits the reaction [Arsenic Trioxide results in decreased expression of NFE2L2 protein]; crocin inhibits the reaction [Cisplatin results in decreased expression of NFE2L2 protein] CTD PMID:32259551 PMID:32920515 NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 multiple interactions EXP crocin inhibits the reaction [Arsenic Trioxide results in decreased expression of NQO1 protein] CTD PMID:32920515 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G Ostm1 osteoclastogenesis associated transmembrane protein 1 multiple interactions ISO [crocin co-treated with pyrazolanthrone co-treated with TNFSF11 protein] results in decreased expression of OSTM1 mRNA; crocin inhibits the reaction [[TNFSF11 protein co-treated with pyrazolanthrone] results in increased expression of OSTM1 mRNA] CTD PMID:30580027 NCBI chr20:46,071,657...46,187,049
Ensembl chr20:46,153,075...46,187,023
JBrowse link
G Parp1 poly (ADP-ribose) polymerase 1 multiple interactions
increases cleavage
ISO MYCN protein inhibits the reaction [crocin results in increased cleavage of PARP1 protein] CTD PMID:30672053 NCBI chr13:92,307,593...92,339,406
Ensembl chr13:92,307,586...92,339,404
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 decreases expression ISO crocin results in decreased expression of PTGS2 mRNA CTD PMID:32886819 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions EXP crocin inhibits the reaction [Arsenic Trioxide results in increased expression of RELA protein]; crocin inhibits the reaction [Streptozocin results in increased expression of RELA protein] CTD PMID:29409856 PMID:32920515 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Smad2 SMAD family member 2 decreases expression
multiple interactions
EXP crocin results in decreased expression of SMAD2 protein
Cisplatin inhibits the reaction [crocin results in decreased expression of SMAD2 protein]; crocin inhibits the reaction [Cisplatin results in increased expression of SMAD2 protein]
CTD PMID:32259551 NCBI chr18:69,849,884...69,918,926
Ensembl chr18:69,850,377...69,912,323
JBrowse link
G Stat3 signal transducer and activator of transcription 3 multiple interactions ISO crocin affects the expression of and affects the phosphorylation of STAT3 protein CTD PMID:32886819 NCBI chr10:85,811,206...85,863,057
Ensembl chr10:85,811,218...85,863,057
JBrowse link
G Tgfb1 transforming growth factor, beta 1 multiple interactions EXP crocin inhibits the reaction [Cisplatin results in increased expression of TGFB1 protein]; crocin inhibits the reaction [Streptozocin results in increased expression of TGFB1 protein] CTD PMID:29409856 PMID:32259551 NCBI chr 1:81,196,532...81,212,848
Ensembl chr 1:81,196,532...81,212,847
JBrowse link
G Tgfbr1 transforming growth factor, beta receptor 1 multiple interactions EXP crocin inhibits the reaction [Cisplatin results in increased expression of TGFBR1 protein] CTD PMID:32259551 NCBI chr 5:61,653,773...61,710,777
Ensembl chr 5:61,653,233...61,710,777
JBrowse link
G Tlr4 toll-like receptor 4 multiple interactions EXP crocin inhibits the reaction [Cisplatin results in increased expression of TLR4 mRNA]; crocin inhibits the reaction [Cisplatin results in increased expression of TLR4 protein]; crocin inhibits the reaction [Streptozocin results in increased expression of TLR4 protein] CTD PMID:29409856 PMID:32259551 NCBI chr 5:80,145,867...80,159,501
Ensembl chr 5:80,145,826...80,159,628
JBrowse link
G Tnf tumor necrosis factor multiple interactions
decreases expression
EXP
ISO
crocin inhibits the reaction [Arsenic Trioxide results in increased expression of TNF mRNA]; crocin inhibits the reaction [Arsenic Trioxide results in increased expression of TNF protein]; crocin inhibits the reaction [Carbon Tetrachloride results in increased expression of TNF protein]; crocin inhibits the reaction [Doxorubicin results in increased expression of TNF protein]; crocin inhibits the reaction [Ethanol results in decreased expression of TNF protein]
crocin results in decreased expression of TNF mRNA
CTD PMID:25637687 PMID:25899501 PMID:26807765 PMID:32886819 PMID:32920515 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tnfsf11 TNF superfamily member 11 multiple interactions ISO [crocin co-treated with pyrazolanthrone co-treated with TNFSF11 protein] results in decreased expression of OSTM1 mRNA; crocin inhibits the reaction [[TNFSF11 protein co-treated with pyrazolanthrone] results in increased expression of AKT2 mRNA]; crocin inhibits the reaction [[TNFSF11 protein co-treated with pyrazolanthrone] results in increased expression of MAPK3 mRNA]; crocin inhibits the reaction [[TNFSF11 protein co-treated with pyrazolanthrone] results in increased expression of OSTM1 mRNA]; crocin inhibits the reaction [[TNFSF11 protein co-treated with pyrazolanthrone] results in increased expression of TRAF6 mRNA]; crocin inhibits the reaction [[TNFSF11 protein co-treated with Pyruvaldehyde] results in decreased activity of GLO1 protein]; crocin promotes the reaction [pyrazolanthrone inhibits the reaction [TNFSF11 protein results in increased activity of ACP5 protein]] CTD PMID:30580027 NCBI chr15:53,674,990...53,705,171
Ensembl chr15:53,673,877...53,705,445
JBrowse link
G Tnnt2 troponin T2, cardiac type multiple interactions EXP crocin inhibits the reaction [Doxorubicin results in increased expression of TNNT2 protein] CTD PMID:26807765 NCBI chr13:47,267,325...47,285,390
Ensembl chr13:47,267,204...47,285,388
JBrowse link
G Tp53 tumor protein p53 multiple interactions ISO crocin inhibits the reaction [Paraquat results in increased expression of TRP53 mRNA] CTD PMID:31911963 NCBI chr10:54,300,070...54,311,525
Ensembl chr10:54,300,048...54,311,524
JBrowse link
G Traf6 TNF receptor associated factor 6 multiple interactions ISO crocin inhibits the reaction [[TNFSF11 protein co-treated with pyrazolanthrone] results in increased expression of TRAF6 mRNA] CTD PMID:30580027 NCBI chr 3:87,963,517...87,988,316
Ensembl chr 3:87,963,514...87,983,507
JBrowse link
G Vgf VGF nerve growth factor inducible increases expression EXP crocin results in increased expression of VGF protein CTD PMID:24401376 NCBI chr12:19,637,313...19,645,123
Ensembl chr12:19,637,320...19,640,341
JBrowse link
fucoxanthin term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Acox1 acyl-CoA oxidase 1 increases expression ISO fucoxanthin results in increased expression of ACOX1 mRNA CTD PMID:20519145 NCBI chr10:101,406,197...101,431,242
Ensembl chr10:101,406,197...101,431,232
JBrowse link
G Acta1 actin, alpha 1, skeletal muscle multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of ACTA1 mRNA] CTD PMID:33448797 NCBI chr19:51,883,713...51,886,725
Ensembl chr19:51,883,715...51,886,742
JBrowse link
G Adcy7 adenylate cyclase 7 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased methylation of ADCY7 gene]; fucoxanthin inhibits the reaction [Glucose results in increased expression of ADCY7 mRNA] CTD PMID:33448797 NCBI chr19:18,740,875...18,798,924
Ensembl chr19:18,740,875...18,776,311
JBrowse link
G Ak8 adenylate kinase 8 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in increased expression of AK8 mRNA] CTD PMID:33448797 NCBI chr 3:12,028,895...12,144,468
Ensembl chr 3:12,028,954...12,144,465
JBrowse link
G Akt1 AKT serine/threonine kinase 1 multiple interactions ISO fucoxanthin inhibits the reaction [Carrageenan results in increased phosphorylation of AKT1 protein] CTD PMID:26418808 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Alcam activated leukocyte cell adhesion molecule multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in increased expression of ALCAM mRNA] CTD PMID:33448797 NCBI chr11:48,336,123...48,536,296
Ensembl chr11:48,336,169...48,537,954
JBrowse link
G Ankrd61 ankyrin repeat domain 61 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of ANKRD61 mRNA] CTD PMID:33448797 NCBI chr12:10,718,908...10,723,267
Ensembl chr12:10,718,908...10,723,265
JBrowse link
G Arhgdib Rho GDP dissociation inhibitor beta multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of ARHGDIB mRNA] CTD PMID:33448797 NCBI chr 4:169,822,951...169,841,884
Ensembl chr 4:169,822,952...169,841,658
JBrowse link
G Armcx6 armadillo repeat containing, X-linked 6 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in increased expression of ARMCX6 mRNA] CTD PMID:33448797 NCBI chr  X:97,929,032...97,932,032
Ensembl chr  X:97,929,041...97,931,977
JBrowse link
G Atg10 autophagy related 10 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in increased expression of ATG10 mRNA] CTD PMID:33448797 NCBI chr 2:22,109,304...22,398,313
Ensembl chr 2:22,108,426...22,398,233
JBrowse link
G Atp2a1 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of ATP2A1 mRNA] CTD PMID:33448797 NCBI chr 1:181,026,606...181,044,859 JBrowse link
G Bambi BMP and activin membrane-bound inhibitor multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in increased expression of BAMBI mRNA] CTD PMID:33448797 NCBI chr17:54,121,251...54,125,816
Ensembl chr17:54,121,255...54,126,060
JBrowse link
G Bche butyrylcholinesterase multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in increased expression of BCHE mRNA] CTD PMID:33448797 NCBI chr 2:158,308,674...158,401,148
Ensembl chr 2:158,307,584...158,401,148
JBrowse link
G Bcl2l1 Bcl2-like 1 multiple interactions
decreases expression
ISO Acetylcysteine inhibits the reaction [fucoxanthin results in decreased expression of BCL2L1 protein] CTD PMID:20594983 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
JBrowse link
G Casp3 caspase 3 increases cleavage
multiple interactions
ISO fucoxanthin results in increased cleavage of CASP3 protein
Acetylcysteine inhibits the reaction [fucoxanthin results in increased cleavage of CASP3 protein]
CTD PMID:20594983 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp7 caspase 7 multiple interactions
increases cleavage
ISO Acetylcysteine inhibits the reaction [fucoxanthin results in increased cleavage of CASP7 protein] CTD PMID:20594983 NCBI chr 1:255,437,195...255,476,737
Ensembl chr 1:255,437,172...255,476,729
JBrowse link
G Casz1 castor zinc finger 1 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in increased expression of CASZ1 mRNA] CTD PMID:33448797 NCBI chr 5:159,243,965...159,393,935
Ensembl chr 5:159,243,995...159,393,400
JBrowse link
G Cat catalase multiple interactions ISO fucoxanthin inhibits the reaction [Carrageenan results in decreased activity of CAT protein] CTD PMID:26418808 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Ccdc116 coiled-coil domain containing 116 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of CCDC116 mRNA] CTD PMID:33448797 NCBI chr11:83,842,707...83,850,607
Ensembl chr11:83,845,557...83,850,607
JBrowse link
G Ccr10 C-C motif chemokine receptor 10 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in increased expression of CCR10 mRNA] CTD PMID:33448797 NCBI chr10:86,108,551...86,110,988
Ensembl chr10:86,108,551...86,110,988
JBrowse link
G Cd1d1 CD1d1 molecule multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in increased expression of CD1D1 mRNA] CTD PMID:33448797 NCBI chr 2:172,423,582...172,427,089
Ensembl chr 2:172,423,582...172,427,089
JBrowse link
G Celsr1 cadherin, EGF LAG seven-pass G-type receptor 1 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in increased expression of CELSR1 mRNA] CTD PMID:33448797 NCBI chr 7:116,987,616...117,125,035
Ensembl chr 7:116,987,605...117,125,164
JBrowse link
G Cemip cell migration inducing hyaluronidase 1 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in increased expression of CEMIP mRNA] CTD PMID:33448797 NCBI chr 1:137,906,921...138,062,430
Ensembl chr 1:137,908,920...138,062,415
JBrowse link
G Cfp complement factor properdin multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of CFP mRNA] CTD PMID:33448797 NCBI chr  X:1,162,014...1,167,576
Ensembl chr  X:1,161,979...1,167,573
JBrowse link
G Cnn1 calponin 1 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of CNN1 mRNA] CTD PMID:33448797 NCBI chr 8:20,632,434...20,641,097
Ensembl chr 8:20,632,338...20,641,098
JBrowse link
G Col7a1 collagen type VII alpha 1 chain multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of COL7A1 mRNA] CTD PMID:33448797 NCBI chr 8:109,604,877...109,637,252
Ensembl chr 8:109,604,861...109,637,252
JBrowse link
G Cpq carboxypeptidase Q multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of CPQ mRNA] CTD PMID:33448797 NCBI chr 7:64,264,025...64,830,867
Ensembl chr 7:64,264,081...64,724,546
JBrowse link
G Crlf1 cytokine receptor-like factor 1 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in increased expression of CRLF1 mRNA] CTD PMID:33448797 NCBI chr16:18,924,722...18,936,049
Ensembl chr16:18,924,722...18,935,997
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in increased expression of CYP2E1 mRNA] CTD PMID:33448797 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
JBrowse link
G Disp2 dispatched RND transporter family member 2 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in increased expression of DISP2 mRNA] CTD PMID:33448797 NCBI chr 3:105,762,303...105,777,826
Ensembl chr 3:105,762,305...105,777,800
JBrowse link
G Dmtn dematin actin binding protein multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of DMTN mRNA] CTD PMID:33448797 NCBI chr15:45,677,974...45,705,601
Ensembl chr15:45,677,977...45,705,601
JBrowse link
G Drd3 dopamine receptor D3 increases activity ISO fucoxanthin results in increased activity of DRD3 protein CTD PMID:31323226 NCBI chr11:56,879,689...56,931,901
Ensembl chr11:56,879,689...56,940,596
JBrowse link
G Drd4 dopamine receptor D4 increases activity ISO fucoxanthin results in increased activity of DRD4 protein CTD PMID:31323226 NCBI chr 1:196,396,366...196,400,824
Ensembl chr 1:196,396,366...196,399,553
JBrowse link
G Dusp13 dual specificity phosphatase 13 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of DUSP13 mRNA] CTD PMID:33448797 NCBI chr15:2,559,720...2,575,105
Ensembl chr15:2,533,547...2,575,539
JBrowse link
G Elapor1 endosome-lysosome associated apoptosis and autophagy regulator 1 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in increased expression of ELAPOR1 mRNA] CTD PMID:33448797 NCBI chr 2:196,089,199...196,169,055
Ensembl chr 2:196,091,646...196,168,716
JBrowse link
G Esrp1 epithelial splicing regulatory protein 1 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in increased expression of ESRP1 mRNA] CTD PMID:33448797 NCBI chr 5:24,427,611...24,482,157
Ensembl chr 5:24,428,717...24,482,062
JBrowse link
G Fam78b family with sequence similarity 78, member B multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of FAM78B mRNA] CTD PMID:33448797 NCBI chr13:79,162,405...79,250,958 JBrowse link
G Fam83c family with sequence similarity 83, member C multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in increased expression of FAM83C mRNA] CTD PMID:33448797 NCBI chr 3:144,333,736...144,339,758
Ensembl chr 3:144,332,982...144,339,802
JBrowse link
G Fam98c family with sequence similarity 98, member C multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of FAM98C mRNA] CTD PMID:33448797 NCBI chr 1:84,452,806...84,456,414
Ensembl chr 1:84,452,814...84,456,385
JBrowse link
G Fbp2 fructose-bisphosphatase 2 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of FBP2 mRNA] CTD PMID:33448797 NCBI chr17:2,236,088...2,253,702
Ensembl chr17:2,236,336...2,253,698
JBrowse link
G Fcho1 FCH and mu domain containing endocytic adaptor 1 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of FCHO1 mRNA] CTD PMID:33448797 NCBI chr16:18,413,452...18,430,795
Ensembl chr16:18,413,363...18,435,104
JBrowse link
G Fgf1 fibroblast growth factor 1 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of FGF1 mRNA] CTD PMID:33448797 NCBI chr18:30,686,555...30,772,667
Ensembl chr18:30,686,581...30,772,357
JBrowse link
G Fgl2 fibrinogen-like 2 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in increased expression of FGL2 mRNA] CTD PMID:33448797 NCBI chr 4:13,710,566...13,716,207
Ensembl chr 4:13,710,575...13,716,207
JBrowse link
G Flg filaggrin decreases expression ISO fucoxanthin results in decreased expression of FLG mRNA CTD PMID:27590588 NCBI chr 2:178,888,688...178,912,731 JBrowse link
G Gask1b golgi associated kinase 1B multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of GASK1B mRNA] CTD PMID:33448797 NCBI chr 2:165,047,689...165,112,479
Ensembl chr 2:165,047,684...165,112,477
JBrowse link
G Gja1 gap junction protein, alpha 1 increases expression ISO fucoxanthin results in increased expression of GJA1 mRNA; fucoxanthin results in increased expression of GJA1 protein CTD PMID:19737546 NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582
JBrowse link
G Gjb1 gap junction protein, beta 1 increases expression ISO fucoxanthin results in increased expression of GJB1 mRNA; fucoxanthin results in increased expression of GJB1 protein CTD PMID:19737546 NCBI chr  X:66,501,848...66,509,783
Ensembl chr  X:66,501,820...66,509,925
JBrowse link
G Gng2 G protein subunit gamma 2 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in increased expression of GNG2 mRNA] CTD PMID:33448797 NCBI chr15:4,316,038...4,416,918
Ensembl chr15:4,316,059...4,417,183
JBrowse link
G Gpm6b glycoprotein m6b multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of GPM6B mRNA] CTD PMID:33448797 NCBI chr  X:28,057,788...28,204,409
Ensembl chr  X:28,059,450...28,204,211
JBrowse link
G Grin1 glutamate ionotropic receptor NMDA type subunit 1 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of GRIN1 mRNA] CTD PMID:33448797 NCBI chr 3:8,103,680...8,130,603
Ensembl chr 3:8,103,680...8,130,603
JBrowse link
G Gypc glycophorin C (Gerbich blood group) multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in increased expression of GYPC mRNA] CTD PMID:33448797 NCBI chr18:24,160,738...24,193,408
Ensembl chr18:24,160,739...24,193,204
JBrowse link
G Hhat hedgehog acyltransferase multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of HHAT mRNA] CTD PMID:33448797 NCBI chr13:104,024,507...104,283,581
Ensembl chr13:104,010,916...104,282,893
JBrowse link
G Hmgcr 3-hydroxy-3-methylglutaryl-CoA reductase decreases activity ISO fucoxanthin results in decreased activity of HMGCR protein CTD PMID:20519145 NCBI chr 2:27,997,523...28,018,983
Ensembl chr 2:27,997,525...28,019,703
JBrowse link
G Hmox1 heme oxygenase 1 increases expression EXP
ISO
fucoxanthin results in increased expression of HMOX1 protein CTD PMID:23358145 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hunk hormonally upregulated Neu-associated kinase multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of HUNK mRNA] CTD PMID:33448797 NCBI chr11:29,641,051...29,758,392
Ensembl chr11:29,640,775...29,757,526
JBrowse link
G Ica1l islet cell autoantigen 1-like multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of ICA1L mRNA] CTD PMID:33448797 NCBI chr 9:61,410,959...61,469,884
Ensembl chr 9:61,412,091...61,470,134
JBrowse link
G Icam5 intercellular adhesion molecule 5 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of ICAM5 mRNA] CTD PMID:33448797 NCBI chr 8:19,567,390...19,575,588
Ensembl chr 8:19,568,600...19,575,588
JBrowse link
G Ifi44 interferon-induced protein 44 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in increased expression of IFI44 mRNA] CTD PMID:33448797 NCBI chr 2:240,626,058...240,643,879
Ensembl chr 2:240,626,066...240,643,844
JBrowse link
G Il1b interleukin 1 beta multiple interactions ISO fucoxanthin analog inhibits the reaction [Lipopolysaccharides results in increased expression of IL1B mRNA] CTD PMID:22735499 NCBI chr 3:116,577,005...116,583,386
Ensembl chr 3:116,577,010...116,583,415
JBrowse link
G Il23r interleukin 23 receptor multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of IL23R mRNA] CTD PMID:33448797 NCBI chr 4:96,580,568...96,672,540
Ensembl chr 4:96,580,714...96,674,021
JBrowse link
G Il24 interleukin 24 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of IL24 mRNA] CTD PMID:33448797 NCBI chr13:42,353,089...42,358,487
Ensembl chr13:42,353,090...42,358,487
JBrowse link
G Il6 interleukin 6 multiple interactions ISO fucoxanthin analog inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 mRNA]; fucoxanthin analog inhibits the reaction [Lipopolysaccharides results in increased expression of IL6 protein] CTD PMID:22735499 NCBI chr 4:5,214,602...5,219,178
Ensembl chr 4:5,213,394...5,219,178
JBrowse link
G Irag1 inositol 1,4,5-triphosphate receptor associated 1 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of IRAG1 mRNA] CTD PMID:33448797 NCBI chr 1:164,981,716...165,094,232
Ensembl chr 1:164,981,716...165,094,176
JBrowse link
G Irf7 interferon regulatory factor 7 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in increased expression of IRF7 mRNA] CTD PMID:33448797 NCBI chr 1:196,367,380...196,370,943
Ensembl chr 1:196,367,361...196,370,832
JBrowse link
G Kcnip2 potassium voltage-gated channel interacting protein 2 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of KCNIP2 mRNA]; fucoxanthin inhibits the reaction [Glucose results in increased methylation of KCNIP2 gene] CTD PMID:33448797 NCBI chr 1:244,641,147...244,664,939
Ensembl chr 1:244,641,150...244,664,874
JBrowse link
G Lpcat1 lysophosphatidylcholine acyltransferase 1 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of LPCAT1 mRNA] CTD PMID:33448797 NCBI chr 1:29,766,070...29,816,401
Ensembl chr 1:29,766,071...29,816,401
JBrowse link
G Lrrc61 leucine rich repeat containing 61 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in increased expression of LRRC61 mRNA] CTD PMID:33448797 NCBI chr 4:77,503,857...77,523,909
Ensembl chr 4:77,503,857...77,524,020
JBrowse link
G Ltc4s leukotriene C4 synthase multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in increased expression of LTC4S mRNA] CTD PMID:33448797 NCBI chr10:34,560,476...34,562,790
Ensembl chr10:34,560,360...34,562,651
JBrowse link
G Ly96 lymphocyte antigen 96 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in increased expression of LY96 mRNA] CTD PMID:33448797 NCBI chr 5:2,582,233...2,612,357
Ensembl chr 5:2,582,254...2,612,386
JBrowse link
G Mak male germ cell-associated kinase multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of MAK mRNA] CTD PMID:33448797 NCBI chr17:23,683,674...23,731,125
Ensembl chr17:23,693,878...23,730,001
JBrowse link
G Mamdc2 MAM domain containing 2 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of MAMDC2 mRNA] CTD PMID:33448797 NCBI chr 1:220,863,959...221,016,493
Ensembl chr 1:220,863,976...221,016,354
JBrowse link
G Maoa monoamine oxidase A decreases activity ISO fucoxanthin results in decreased activity of MAOA protein CTD PMID:31323226 NCBI chr  X:6,032,172...6,098,308
Ensembl chr  X:6,030,795...6,099,593
JBrowse link
G Maob monoamine oxidase B decreases activity ISO fucoxanthin results in decreased activity of MAOB protein CTD PMID:31323226 NCBI chr  X:5,907,327...6,010,996
Ensembl chr  X:5,907,266...6,011,003
JBrowse link
G Map3k13 mitogen-activated protein kinase kinase kinase 13 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of MAP3K13 mRNA] CTD PMID:33448797 NCBI chr11:79,094,087...79,235,181
Ensembl chr11:79,097,247...79,235,181
JBrowse link
G Mapk1 mitogen activated protein kinase 1 multiple interactions ISO fucoxanthin inhibits the reaction [Carrageenan results in increased phosphorylation of MAPK1 protein] CTD PMID:26418808 NCBI chr11:83,957,813...84,023,629
Ensembl chr11:83,957,813...84,023,616
JBrowse link
G Mapk3 mitogen activated protein kinase 3 multiple interactions ISO fucoxanthin inhibits the reaction [Carrageenan results in increased phosphorylation of MAPK3 protein] CTD PMID:26418808 NCBI chr 1:181,366,646...181,372,863
Ensembl chr 1:181,366,637...181,372,863
JBrowse link
G Mfsd3 major facilitator superfamily domain containing 3 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in increased expression of MFSD3 mRNA] CTD PMID:33448797 NCBI chr 7:108,419,644...108,423,469
Ensembl chr 7:108,421,350...108,423,461
JBrowse link
G Myo7b myosin VIIb multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of MYO7B mRNA] CTD PMID:33448797 NCBI chr18:23,588,307...23,669,841
Ensembl chr18:23,588,307...23,669,809
JBrowse link
G Nkd2 NKD inhibitor of WNT signaling pathway 2 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of NKD2 mRNA] CTD PMID:33448797 NCBI chr 1:29,442,898...29,470,839
Ensembl chr 1:29,441,328...29,470,821
JBrowse link
G Nos2 nitric oxide synthase 2 multiple interactions ISO fucoxanthin analog inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 mRNA]; fucoxanthin analog inhibits the reaction [Lipopolysaccharides results in increased expression of NOS2 protein]; fucoxanthin inhibits the reaction [Carrageenan results in increased expression of NOS2 protein] CTD PMID:22735499 PMID:26418808 NCBI chr10:63,815,308...63,851,208
Ensembl chr10:63,815,308...63,851,210
JBrowse link
G Nrbp2 nuclear receptor binding protein 2 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of NRBP2 mRNA] CTD PMID:33448797 NCBI chr 7:107,798,642...107,805,230
Ensembl chr 7:107,799,497...107,805,230
JBrowse link
G Ntm neurotrimin multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in increased expression of NTM mRNA] CTD PMID:33448797 NCBI chr 8:27,376,582...28,366,604
Ensembl chr 8:27,377,773...28,366,595
JBrowse link
G Nxpe4 neurexophilin and PC-esterase domain family member 4 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of NXPE4 mRNA] CTD PMID:33448797 NCBI chr 8:48,502,697...48,744,101
Ensembl chr 8:48,722,440...48,744,100
JBrowse link
G Oas3 2'-5'-oligoadenylate synthetase 3 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in increased expression of OAS3 mRNA] CTD PMID:33448797 NCBI chr12:35,779,028...35,802,781
Ensembl chr12:35,779,022...35,802,781
JBrowse link
G Pacsin1 protein kinase C and casein kinase substrate in neurons 1 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in increased expression of PACSIN1 mRNA] CTD PMID:33448797 NCBI chr20:5,718,134...5,768,064
Ensembl chr20:5,719,857...5,765,313
JBrowse link
G Pcdh17 protocadherin 17 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in increased expression of PCDH17 mRNA] CTD PMID:33448797 NCBI chr15:60,222,088...60,316,172
Ensembl chr15:60,222,004...60,313,999
JBrowse link
G Pcdhgb6 protocadherin gamma subfamily B, 6 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in increased expression of PCDHGB6 mRNA] CTD PMID:33448797
G Pip5k1b phosphatidylinositol-4-phosphate 5-kinase type 1 beta multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased methylation of PIP5K1B gene]; fucoxanthin inhibits the reaction [Glucose results in increased expression of PIP5K1B mRNA] CTD PMID:33448797 NCBI chr 1:221,907,220...222,183,672
Ensembl chr 1:221,914,159...222,183,672
JBrowse link
G Pitpnm3 PITPNM family member 3 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of PITPNM3 mRNA] CTD PMID:33448797 NCBI chr10:56,674,697...56,766,552
Ensembl chr10:56,676,261...56,766,584
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha increases expression ISO fucoxanthin results in increased expression of PPARA mRNA CTD PMID:20519145 NCBI chr 7:116,832,405...116,900,878
Ensembl chr 7:116,832,756...116,895,346
JBrowse link
G Pparg peroxisome proliferator-activated receptor gamma decreases expression ISO fucoxanthin results in decreased expression of PPARG mRNA CTD PMID:20519145 NCBI chr 4:148,423,102...148,548,471
Ensembl chr 4:148,423,194...148,548,468
JBrowse link
G Psen2 presenilin 2 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of PSEN2 mRNA] CTD PMID:33448797 NCBI chr13:91,967,506...91,993,240
Ensembl chr13:91,967,983...91,993,174
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO fucoxanthin analog affects the reaction [Lipopolysaccharides results in increased expression of PTGS2 mRNA]; fucoxanthin analog affects the reaction [Lipopolysaccharides results in increased expression of PTGS2 protein]; fucoxanthin inhibits the reaction [Carrageenan results in increased expression of PTGS2 protein] CTD PMID:22735499 PMID:26418808 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Rab40b Rab40b, member RAS oncogene family multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of RAB40B mRNA] CTD PMID:33448797 NCBI chr10:106,631,514...106,659,090
Ensembl chr10:106,631,514...106,659,090
JBrowse link
G Retn resistin decreases expression ISO fucoxanthin results in decreased expression of RETN protein CTD PMID:20519145 NCBI chr12:1,710,881...1,712,621
Ensembl chr12:1,710,881...1,712,620
JBrowse link
G Rimbp3 RIMS binding protein 3 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in increased expression of RIMBP3 mRNA] CTD PMID:33448797 NCBI chr11:83,783,816...83,789,391
Ensembl chr11:83,784,244...83,789,082
JBrowse link
G Rtp4 receptor (chemosensory) transporter protein 4 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in increased expression of RTP4 mRNA] CTD PMID:33448797 NCBI chr11:77,237,341...77,249,194
Ensembl chr11:77,238,216...77,335,437
JBrowse link
G Shc4 SHC adaptor protein 4 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in increased expression of SHC4 mRNA] CTD PMID:33448797 NCBI chr 3:112,880,598...112,974,216
Ensembl chr 3:112,880,600...112,974,366
JBrowse link
G Slc16a5 solute carrier family 16 member 5 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of SLC16A5 mRNA] CTD PMID:33448797 NCBI chr10:100,707,434...100,721,338
Ensembl chr10:100,707,434...100,721,338
JBrowse link
G Slc18a2 solute carrier family 18 member A2 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of SLC18A2 mRNA] CTD PMID:33448797 NCBI chr 1:258,413,748...258,449,143
Ensembl chr 1:258,413,959...258,448,325
JBrowse link
G Slc6a18 solute carrier family 6 member 18 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in increased expression of SLC6A18 mRNA] CTD PMID:33448797 NCBI chr 1:29,607,288...29,621,925
Ensembl chr 1:29,608,077...29,621,925
JBrowse link
G Strip2 striatin interacting protein 2 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in increased expression of STRIP2 mRNA] CTD PMID:33448797 NCBI chr 4:58,536,034...58,578,279
Ensembl chr 4:58,536,055...58,578,291
JBrowse link
G Syn1 synapsin I multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of SYN1 mRNA] CTD PMID:33448797 NCBI chr  X:1,172,208...1,227,400
Ensembl chr  X:1,172,208...1,227,396
JBrowse link
G Synpo2l synaptopodin 2-like multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of SYNPO2L mRNA] CTD PMID:33448797 NCBI chr15:3,631,974...3,641,429
Ensembl chr15:3,631,834...3,641,429
JBrowse link
G Tgfb1i1 transforming growth factor beta 1 induced transcript 1 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of TGFB1I1 mRNA] CTD PMID:33448797 NCBI chr 1:182,828,553...182,835,465
Ensembl chr 1:182,828,544...182,837,080
JBrowse link
G Thsd7a thrombospondin type 1 domain containing 7A multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in increased expression of THSD7A mRNA] CTD PMID:33448797 NCBI chr 4:40,461,124...40,899,345
Ensembl chr 4:40,460,814...40,899,583
JBrowse link
G Tmeff1 transmembrane protein with EGF-like and two follistatin-like domains 1 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of TMEFF1 mRNA]; fucoxanthin inhibits the reaction [Glucose results in increased methylation of TMEFF1 gene] CTD PMID:33448797 NCBI chr 5:62,910,740...62,996,494
Ensembl chr 5:62,910,740...62,996,493
JBrowse link
G Tmem229b transmembrane protein 229B multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of TMEM229B mRNA] CTD PMID:33448797 NCBI chr 6:97,771,645...97,819,582
Ensembl chr 6:97,775,332...97,819,489
JBrowse link
G Tnf tumor necrosis factor multiple interactions ISO fucoxanthin analog inhibits the reaction [Lipopolysaccharides results in increased expression of TNF mRNA]; fucoxanthin analog inhibits the reaction [Lipopolysaccharides results in increased expression of TNF protein] CTD PMID:22735499 NCBI chr20:3,622,011...3,624,629
Ensembl chr20:3,622,011...3,624,629
JBrowse link
G Tnfsf13 TNF superfamily member 13 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of TNFSF13 mRNA] CTD PMID:33448797 NCBI chr10:54,400,054...54,403,723
Ensembl chr10:54,400,065...54,403,042
JBrowse link
G Ttc21a tetratricopeptide repeat domain 21A multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of TTC21A mRNA] CTD PMID:33448797 NCBI chr 8:119,667,044...119,702,028
Ensembl chr 8:119,666,933...119,702,456
JBrowse link
G Wnt7b Wnt family member 7B multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of WNT7B mRNA] CTD PMID:33448797 NCBI chr 7:116,634,817...116,679,089
Ensembl chr 7:116,634,814...116,679,581
JBrowse link
G Zfp521 zinc finger protein 521 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of ZFP521 mRNA] CTD PMID:33448797 NCBI chr18:4,775,952...5,068,592
Ensembl chr18:4,787,295...5,068,458
JBrowse link
G Zfp566 zinc finger protein 566 multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in increased expression of ZFP566 mRNA] CTD PMID:33448797 NCBI chr 1:85,318,449...85,342,186
Ensembl chr 1:85,318,452...85,333,161
JBrowse link
G Zxdc ZXD family zinc finger C multiple interactions ISO fucoxanthin inhibits the reaction [Glucose results in decreased expression of ZXDA mRNA] CTD PMID:33448797 NCBI chr 4:122,882,389...122,914,486
Ensembl chr 4:122,882,336...122,916,496
JBrowse link
lutein term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Als2 alsin Rho guanine nucleotide exchange factor ALS2 multiple interactions
decreases expression
ISO [Cisplatin co-treated with Lutein] results in decreased expression of ALS2 mRNA; [Cisplatin co-treated with Lutein] results in increased expression of ALS2 mRNA
Lutein results in decreased expression of ALS2 mRNA
CTD PMID:24865317 NCBI chr 9:60,613,182...60,686,394
Ensembl chr 9:60,613,167...60,670,737
JBrowse link
G Apc APC regulator of WNT signaling pathway multiple interactions ISO [Cisplatin co-treated with Lutein] results in increased expression of APC mRNA CTD PMID:24865317 NCBI chr18:25,828,558...25,925,511
Ensembl chr18:25,864,222...25,922,696
JBrowse link
G Aqr aquarius intron-binding spliceosomal factor decreases expression
multiple interactions
ISO Lutein results in decreased expression of AQR mRNA
[Cisplatin co-treated with Lutein] results in decreased expression of AQR mRNA
CTD PMID:24865317 NCBI chr 3:100,874,987...100,945,026
Ensembl chr 3:100,874,987...100,945,044
JBrowse link
G Atr ATR serine/threonine kinase multiple interactions
decreases expression
ISO [Cisplatin co-treated with Lutein] results in decreased expression of ATR mRNA
Lutein results in decreased expression of ATR mRNA
CTD PMID:24865317 NCBI chr 8:96,426,704...96,524,152
Ensembl chr 8:96,426,724...96,524,136
JBrowse link
G Bax BCL2 associated X, apoptosis regulator increases expression ISO Lutein results in increased expression of BAX protein CTD PMID:17455471 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bcl2 BCL2, apoptosis regulator decreases expression ISO Lutein results in decreased expression of BCL2 protein CTD PMID:17455471 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Bcl2l1 Bcl2-like 1 increases expression ISO Lutein results in increased expression of BCL2L1 protein CTD PMID:10750663 NCBI chr 3:141,253,508...141,304,582
Ensembl chr 3:141,253,523...141,303,479
JBrowse link
G Bco2 beta-carotene oxygenase 2 increases metabolic processing
affects metabolic processing
multiple interactions
ISO BCO2 protein results in increased metabolism of Lutein
BCO2 protein affects the metabolism of Lutein
[BCO2 protein affects the metabolism of Lutein] which results in increased abundance of 3'-dehydrolutein; [BCO2 protein results in increased metabolism of Lutein] which results in increased chemical synthesis of apocarotenal metabolite
CTD PMID:21106934 NCBI chr 8:50,882,174...50,907,676
Ensembl chr 8:50,882,181...50,915,467
JBrowse link
G Cat catalase multiple interactions ISO Lutein inhibits the reaction [deoxynivalenol results in increased expression of CAT protein] CTD PMID:20347963 NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Ccnd1 cyclin D1 decreases expression ISO Lutein results in decreased expression of CCND1 protein CTD PMID:17718427 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Ccs copper chaperone for superoxide dismutase increases expression ISO Lutein results in increased expression of CCS mRNA CTD PMID:24865317 NCBI chr 1:202,113,792...202,134,931
Ensembl chr 1:202,113,804...202,134,915
JBrowse link
G Cfd complement factor D decreases expression
decreases secretion
ISO Lutein results in decreased expression of CFD mRNA
Lutein results in decreased secretion of CFD protein
CTD PMID:26504594 NCBI chr 7:9,813,148...9,814,871
Ensembl chr 7:9,813,150...9,815,053
JBrowse link
G Ctsb cathepsin B increases expression
multiple interactions
ISO Lutein results in increased expression of CTSB mRNA
Cisplatin inhibits the reaction [Lutein results in increased expression of CTSB mRNA]
CTD PMID:24865317 NCBI chr15:37,389,636...37,410,508
Ensembl chr15:37,389,629...37,410,500
JBrowse link
G Cyba cytochrome b-245 alpha chain multiple interactions
decreases expression
ISO [Cisplatin co-treated with Lutein] results in decreased expression of CYBA mRNA
Lutein results in decreased expression of CYBA mRNA
CTD PMID:24865317 NCBI chr19:50,487,598...50,495,669
Ensembl chr19:50,487,597...50,495,721
JBrowse link
G Ercc2 ERCC excision repair 2, TFIIH core complex helicase subunit decreases expression
multiple interactions
ISO Lutein results in decreased expression of ERCC2 mRNA
[Cisplatin co-treated with Lutein] results in decreased expression of ERCC2 mRNA
CTD PMID:24865317 NCBI chr 1:79,033,342...79,047,102
Ensembl chr 1:79,033,326...79,047,102
JBrowse link
G Ercc6 ERCC excision repair 6, chromatin remodeling factor decreases expression ISO Lutein results in decreased expression of ERCC6 mRNA CTD PMID:24865317 NCBI chr16:7,764,983...7,835,587
Ensembl chr16:7,765,013...7,835,587
JBrowse link
G Fmo2 flavin containing dimethylaniline monoxygenase 2 decreases expression ISO Lutein results in decreased expression of FMO2 mRNA CTD PMID:24865317 NCBI chr13:75,221,149...75,244,377
Ensembl chr13:75,224,402...75,244,308
JBrowse link
G Gab1 GRB2-associated binding protein 1 decreases expression
multiple interactions
ISO Lutein results in decreased expression of GAB1 mRNA
[Cisplatin co-treated with Lutein] results in decreased expression of GAB1 mRNA
CTD PMID:24865317 NCBI chr19:27,131,262...27,239,236
Ensembl chr19:27,131,262...27,239,236
JBrowse link
G Gpx1 glutathione peroxidase 1 multiple interactions
increases expression
ISO Cisplatin inhibits the reaction [Lutein results in increased expression of GPX1 mRNA]; Lutein inhibits the reaction [Lipopolysaccharides results in decreased expression of GPX1 mRNA] CTD PMID:22040935 PMID:24865317 NCBI chr 8:109,026,905...109,028,031
Ensembl chr 8:109,026,905...109,028,024
JBrowse link
G Gpx2 glutathione peroxidase 2 multiple interactions ISO [Lutein co-treated with Cisplatin] results in increased expression of GPX2 mRNA CTD PMID:24865317 NCBI chr 6:95,493,589...95,496,877
Ensembl chr 6:95,493,589...95,496,877
JBrowse link
G Gpx3 glutathione peroxidase 3 multiple interactions ISO [Cisplatin co-treated with Lutein] results in decreased expression of GPX3 mRNA CTD PMID:24865317 NCBI chr10:39,028,624...39,036,695
Ensembl chr10:39,028,570...39,037,035
JBrowse link
G Gsr glutathione-disulfide reductase increases expression
multiple interactions
ISO Lutein results in increased expression of GSR mRNA
[Cisplatin co-treated with Lutein] results in decreased expression of GSR mRNA
CTD PMID:24865317 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
JBrowse link
G Gstk1 glutathione S-transferase kappa 1 multiple interactions ISO [Cisplatin co-treated with Lutein] results in decreased expression of GSTK1 mRNA CTD PMID:24865317 NCBI chr 4:71,118,979...71,123,298
Ensembl chr 4:71,118,896...71,123,292
JBrowse link
G Hmox1 heme oxygenase 1 multiple interactions
increases expression
ISO arsenic trioxide promotes the reaction [Lutein results in increased expression of HMOX1 mRNA]; arsenic trioxide promotes the reaction [Lutein results in increased expression of HMOX1 protein]; Lutein promotes the reaction [arsenic trioxide results in increased expression of HMOX1 mRNA]; Lutein promotes the reaction [arsenic trioxide results in increased expression of HMOX1 protein]
Lutein results in increased expression of HMOX1 mRNA; Lutein results in increased expression of HMOX1 protein
CTD PMID:25815309 PMID:26187899 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Idh1 isocitrate dehydrogenase (NADP(+)) 1 multiple interactions
decreases expression
ISO [Cisplatin co-treated with Lutein] results in decreased expression of IDH1 mRNA
Lutein results in decreased expression of IDH1 mRNA
CTD PMID:24865317 NCBI chr 9:66,534,146...66,563,703
Ensembl chr 9:66,534,146...66,563,708
JBrowse link
G Ift172 intraflagellar transport 172 multiple interactions
decreases expression
ISO [Cisplatin co-treated with Lutein] results in decreased expression of IFT172 mRNA
Lutein results in decreased expression of IFT172 mRNA
CTD PMID:24865317 NCBI chr 6:25,081,933...25,121,271 JBrowse link
G Kif9 kinesin family member 9 multiple interactions
increases expression
ISO Lutein promotes the reaction [Cisplatin results in decreased expression of KIF9 mRNA]
Lutein results in increased expression of KIF9 mRNA
CTD PMID:24865317 NCBI chr 8:110,459,467...110,504,492
Ensembl chr 8:110,459,383...110,505,252
JBrowse link
G Mb myoglobin increases expression ISO Lutein results in increased expression of MB mRNA CTD PMID:24865317 NCBI chr 7:108,759,903...108,767,134
Ensembl chr 7:108,759,904...108,767,383
JBrowse link
G Mgst1 microsomal glutathione S-transferase 1 multiple interactions
increases expression
ISO arsenic trioxide promotes the reaction [Lutein results in increased expression of MGST1 mRNA]; Lutein promotes the reaction [arsenic trioxide results in increased expression of MGST1 mRNA] CTD PMID:25815309 PMID:26187899 NCBI chr 4:171,029,666...171,044,893
Ensembl chr 4:171,029,630...171,044,892
JBrowse link
G Nfe2l2 NFE2 like bZIP transcription factor 2 multiple interactions
increases expression
ISO arsenic trioxide promotes the reaction [Lutein results in increased expression of NFE2L2 mRNA]; arsenic trioxide promotes the reaction [Lutein results in increased expression of NFE2L2 protein]; Lutein promotes the reaction [arsenic trioxide results in increased expression of NFE2L2 mRNA]; Lutein promotes the reaction [arsenic trioxide results in increased expression of NFE2L2 protein]; Lutein results in increased expression of and affects the localization of NFE2L2 protein
Lutein results in increased expression of NFE2L2 mRNA; Lutein results in increased expression of NFE2L2 protein
CTD PMID:25815309 PMID:26187899 NCBI chr 3:60,594,239...60,621,785
Ensembl chr 3:60,594,242...60,621,737
JBrowse link
G Ngb neuroglobin increases expression ISO Lutein results in increased expression of NGB mRNA CTD PMID:24865317 NCBI chr 6:106,744,378...106,749,830
Ensembl chr 6:106,744,378...106,749,830
JBrowse link
G Nox4 NADPH oxidase 4 multiple interactions
decreases expression
ISO [Cisplatin co-treated with Lutein] results in decreased expression of NOX4 mRNA
Lutein results in decreased expression of NOX4 mRNA
CTD PMID:24865317 NCBI chr 1:140,900,886...141,078,844
Ensembl chr 1:140,901,097...141,077,406
JBrowse link
G Noxo1 NADPH oxidase organizer 1 multiple interactions ISO [Cisplatin co-treated with Lutein] results in decreased expression of NOXO1 mRNA CTD PMID:24865317 NCBI chr10:13,721,473...13,726,061
Ensembl chr10:13,721,473...13,726,061
JBrowse link
G Nqo1 NAD(P)H quinone dehydrogenase 1 multiple interactions
increases expression
ISO [Cisplatin co-treated with Lutein] results in increased expression of NQO1 mRNA; arsenic trioxide promotes the reaction [Lutein results in increased expression of NQO1 mRNA]; arsenic trioxide promotes the reaction [Lutein results in increased expression of NQO1 protein]; Lutein promotes the reaction [arsenic trioxide results in increased expression of NQO1 mRNA]; Lutein promotes the reaction [arsenic trioxide results in increased expression of NQO1 protein]
Lutein results in increased expression of NQO1 mRNA; Lutein results in increased expression of NQO1 protein
CTD PMID:24865317 PMID:25815309 PMID:26187899 NCBI chr19:35,295,633...35,310,528
Ensembl chr19:35,295,573...35,310,557
JBrowse link
G Nudt15 nudix hydrolase 15 decreases expression
multiple interactions
ISO Lutein results in decreased expression of NUDT15 mRNA
[Cisplatin co-treated with Lutein] results in decreased expression of NUDT15 mRNA
CTD PMID:24865317 NCBI chr15:48,707,776...48,747,363
Ensembl chr15:48,709,700...48,747,363
JBrowse link
G Nxn nucleoredoxin increases expression
multiple interactions
ISO Lutein results in increased expression of NXN mRNA
Lutein inhibits the reaction [Cisplatin results in increased expression of NXN mRNA]
CTD PMID:24865317 NCBI chr10:61,109,323...61,247,576
Ensembl chr10:61,110,020...61,248,251
JBrowse link
G Park7 Parkinsonism associated deglycase multiple interactions ISO [Cisplatin co-treated with Lutein] results in decreased expression of PARK7 mRNA CTD PMID:24865317 NCBI chr 5:161,353,718...161,376,993
Ensembl chr 5:161,353,719...161,376,970
JBrowse link
G Ppp1r15b protein phosphatase 1, regulatory subunit 15B multiple interactions
decreases expression
ISO [Cisplatin co-treated with Lutein] results in decreased expression of PPP1R15B mRNA
Lutein results in decreased expression of PPP1R15B mRNA
CTD PMID:24865317 NCBI chr13:44,577,840...44,585,737
Ensembl chr13:44,577,932...44,585,737
JBrowse link
G Prdx4 peroxiredoxin 4 increases expression ISO Lutein results in increased expression of PRDX4 mRNA CTD PMID:24865317 NCBI chr  X:40,026,762...40,044,066
Ensembl chr  X:40,026,651...40,044,066
JBrowse link
G Prdx5 peroxiredoxin 5 decreases expression ISO Lutein results in decreased expression of PRDX5 mRNA CTD PMID:24865317 NCBI chr 1:204,099,826...204,103,589
Ensembl chr 1:204,099,826...204,114,268
JBrowse link
G Prdx6 peroxiredoxin 6 multiple interactions
decreases expression
ISO [Cisplatin co-treated with Lutein] results in decreased expression of PRDX6 mRNA
Lutein results in decreased expression of PRDX6 mRNA
CTD PMID:24865317 NCBI chr13:73,528,746...73,539,295
Ensembl chr13:73,528,210...73,539,355
JBrowse link
G Ptgs1 prostaglandin-endoperoxide synthase 1 multiple interactions ISO [Cisplatin co-treated with Lutein] results in decreased expression of PTGS1 mRNA CTD PMID:24865317 NCBI chr 3:19,584,015...19,605,589
Ensembl chr 3:19,584,015...19,605,586
JBrowse link
G Ptgs2 prostaglandin-endoperoxide synthase 2 multiple interactions ISO Lutein inhibits the reaction [deoxynivalenol results in increased expression of PTGS2 protein] CTD PMID:20347963 NCBI chr13:62,164,080...62,169,770
Ensembl chr13:62,163,932...62,172,188
JBrowse link
G Rela RELA proto-oncogene, NF-kB subunit multiple interactions ISO Lutein inhibits the reaction [deoxynivalenol affects the localization of RELA protein]; Lutein inhibits the reaction [deoxynivalenol results in increased expression of RELA protein] CTD PMID:20347963 NCBI chr 1:202,925,001...202,935,484
Ensembl chr 1:202,924,945...202,935,484
JBrowse link
G Scd stearoyl-CoA desaturase multiple interactions
decreases expression
ISO [Cisplatin co-treated with Lutein] results in decreased expression of SCD1 mRNA
Lutein results in decreased expression of SCD1 mRNA
CTD PMID:24865317 NCBI chr 1:243,269,745...243,282,878
Ensembl chr 1:243,269,747...243,282,562
JBrowse link
G Sod1 superoxide dismutase 1 multiple interactions
increases expression
ISO Lutein inhibits the reaction [Lipopolysaccharides results in decreased expression of SOD1 mRNA]
Lutein results in increased expression of SOD1 mRNA
CTD PMID:22040935 PMID:24865317 NCBI chr11:29,456,673...29,462,249
Ensembl chr11:29,456,558...29,462,249
JBrowse link
G Sod2 superoxide dismutase 2 multiple interactions
decreases expression
ISO [Cisplatin co-treated with Lutein] results in decreased expression of SOD2 mRNA; Lutein inhibits the reaction [Lipopolysaccharides results in decreased expression of SOD2 mRNA]
Lutein results in decreased expression of SOD2 mRNA
CTD PMID:22040935 PMID:24865317 NCBI chr 1:47,638,318...47,645,163
Ensembl chr 1:47,636,528...47,645,189
JBrowse link
G Sod3 superoxide dismutase 3 multiple interactions
decreases expression
ISO [Cisplatin co-treated with Lutein] results in decreased expression of SOD3 mRNA
Lutein results in decreased expression of SOD3 mRNA
CTD PMID:24865317 NCBI chr14:58,610,104...58,615,845
Ensembl chr14:58,609,958...58,615,990
JBrowse link
G Srxn1 sulfiredoxin 1 multiple interactions
decreases expression
ISO [Cisplatin co-treated with Lutein] results in decreased expression of SRXN1 mRNA
Lutein results in decreased expression of SRXN1 mRNA
CTD PMID:24865317 NCBI chr 3:140,604,490...140,610,050
Ensembl chr 3:140,599,608...140,628,448
JBrowse link
G Txnrd1 thioredoxin reductase 1 decreases expression
multiple interactions
ISO Lutein results in decreased expression of TXNRD1 mRNA
[Cisplatin co-treated with Lutein] results in decreased expression of TXNRD1 mRNA
CTD PMID:24865317 NCBI chr 7:20,830,042...20,914,990
Ensembl chr 7:20,830,045...20,907,863
JBrowse link
G Ucp3 uncoupling protein 3 increases expression ISO Lutein results in increased expression of UCP3 mRNA CTD PMID:24865317 NCBI chr 1:154,815,777...154,828,764
Ensembl chr 1:154,815,777...154,828,762
JBrowse link
G Vim vimentin increases expression ISO Lutein results in increased expression of VIM mRNA CTD PMID:24865317 NCBI chr17:76,668,701...76,677,186
Ensembl chr17:76,668,647...76,677,187
JBrowse link
G Xirp1 xin actin-binding repeat containing 1 increases expression ISO Lutein results in increased expression of XIRP1 mRNA CTD PMID:24865317 NCBI chr 8:119,744,778...119,757,547
Ensembl chr 8:119,747,419...119,757,349
JBrowse link
lycopene term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ache acetylcholinesterase multiple interactions EXP Lycopene inhibits the reaction [manganese chloride results in increased activity of ACHE protein]; Lycopene inhibits the reaction [Sodium Glutamate results in increased activity of ACHE protein] CTD PMID:22192907 PMID:26900785 NCBI chr12:19,407,359...19,413,713
Ensembl chr12:19,407,360...19,413,651
JBrowse link
G Add1 adducin 1 decreases expression ISO lycopene results in decreased expression of ADD1 mRNA CTD PMID:16886892 NCBI chr14:76,108,643...76,167,267
Ensembl chr14:76,108,654...76,167,182
JBrowse link
G Ager advanced glycosylation end product-specific receptor multiple interactions ISO lycopene inhibits the reaction [HMGB1 protein results in increased expression of AGER protein]; lycopene inhibits the reaction [Lipopolysaccharides results in increased expression of AGER protein] CTD PMID:22429818 NCBI chr20:4,148,150...4,151,361
Ensembl chr20:4,147,890...4,151,078
JBrowse link
G Ahr aryl hydrocarbon receptor decreases expression ISO lycopene results in decreased expression of AHR mRNA CTD PMID:16886892 NCBI chr 6:52,234,089...52,271,568
Ensembl chr 6:52,234,089...52,271,568
JBrowse link
G Aif1 allograft inflammatory factor 1 multiple interactions ISO lycopene inhibits the reaction [Galactose results in increased expression of AIF1 protein] CTD PMID:28974442 NCBI chr20:3,646,784...3,652,670
Ensembl chr20:3,646,777...3,652,668
JBrowse link
G Akt1 AKT serine/threonine kinase 1 decreases phosphorylation ISO lycopene results in decreased phosphorylation of AKT1 protein CTD PMID:17337101 NCBI chr 6:131,713,716...131,735,319
Ensembl chr 6:131,713,720...131,733,921
JBrowse link
G Alad aminolevulinate dehydratase multiple interactions ISO
EXP
lycopene inhibits the reaction [Zearalenone results in decreased activity of ALAD protein]
lycopene inhibits the reaction [Mercuric Chloride results in decreased activity of ALAD protein]
CTD PMID:17516994 PMID:25682699 NCBI chr 5:75,961,993...75,972,334
Ensembl chr 5:75,961,993...75,972,474
JBrowse link
G Andpro androgen regulated protein decreases expression EXP lycopene results in decreased expression of ANDPRO mRNA CTD PMID:15084515 NCBI chr 3:136,718,601...136,725,131
Ensembl chr 3:136,718,602...136,724,966
JBrowse link
G Ar androgen receptor decreases expression ISO lycopene results in decreased expression of AR mRNA CTD PMID:16886892 NCBI chr  X:63,104,771...63,273,934
Ensembl chr  X:63,104,771...63,273,925
JBrowse link
G Atf6 activating transcription factor 6 multiple interactions EXP Lycopene inhibits the reaction [Oxaliplatin results in increased expression of ATF6 mRNA] CTD PMID:32544411 NCBI chr13:82,927,579...83,106,381
Ensembl chr13:82,930,034...83,107,177
JBrowse link
G Atg10 autophagy related 10 multiple interactions ISO Lycopene inhibits the reaction [Atrazine results in decreased expression of ATG10 mRNA] CTD PMID:30360616 NCBI chr 2:22,109,304...22,398,313
Ensembl chr 2:22,108,426...22,398,233
JBrowse link
G Atg13 autophagy related 13 multiple interactions ISO Lycopene inhibits the reaction [Atrazine results in increased expression of ATG13 mRNA] CTD PMID:30360616 NCBI chr 3:77,647,069...77,681,028
Ensembl chr 3:77,645,790...77,681,043
JBrowse link
G Atg14 autophagy related 14 multiple interactions ISO Lycopene inhibits the reaction [Atrazine results in increased expression of ATG14 mRNA] CTD PMID:30360616 NCBI chr15:20,795,750...20,827,113
Ensembl chr15:20,795,750...20,827,113
JBrowse link
G Atg16l1 autophagy related 16-like 1 multiple interactions ISO Lycopene inhibits the reaction [Atrazine results in decreased expression of ATG16L1 mRNA] CTD PMID:30360616 NCBI chr 9:88,420,737...88,457,530
Ensembl chr 9:88,422,038...88,457,529
JBrowse link
G Atg16l2 autophagy related 16-like 2 multiple interactions ISO Lycopene inhibits the reaction [Atrazine results in increased expression of ATG16L2 mRNA] CTD PMID:30360616 NCBI chr 1:155,687,386...155,703,419
Ensembl chr 1:155,684,564...155,703,420
JBrowse link
G Atg2b autophagy related 2B multiple interactions ISO Lycopene inhibits the reaction [Atrazine results in increased expression of ATG2B mRNA] CTD PMID:30360616 NCBI chr 6:124,522,283...124,592,412
Ensembl chr 6:124,525,523...124,592,015
JBrowse link
G Atg3 autophagy related 3 multiple interactions ISO Lycopene inhibits the reaction [Atrazine results in decreased expression of ATG3 mRNA] CTD PMID:30360616 NCBI chr11:55,624,928...55,653,212
Ensembl chr11:55,624,917...55,653,224
JBrowse link
G Atg4a autophagy related 4A, cysteine peptidase multiple interactions ISO Lycopene inhibits the reaction [Atrazine results in decreased expression of ATG4A mRNA] CTD PMID:30360616 NCBI chr  X:104,665,345...104,765,271 JBrowse link
G Atg4b autophagy related 4B, cysteine peptidase multiple interactions ISO Lycopene inhibits the reaction [Atrazine results in increased expression of ATG4B mRNA] CTD PMID:30360616 NCBI chr 9:94,282,417...94,314,109
Ensembl chr 9:94,282,509...94,314,103
JBrowse link
G Atg4c autophagy related 4C, cysteine peptidase multiple interactions ISO Lycopene inhibits the reaction [Atrazine results in decreased expression of ATG4C mRNA] CTD PMID:30360616 NCBI chr 5:113,867,218...113,935,534
Ensembl chr 5:113,867,092...113,934,830
JBrowse link
G Atg5 autophagy related 5 multiple interactions ISO Lycopene inhibits the reaction [Atrazine results in decreased expression of ATG5 mRNA] CTD PMID:30360616 NCBI chr20:47,798,222...47,889,216
Ensembl chr20:47,798,290...47,889,209
JBrowse link
G Atg7 autophagy related 7 multiple interactions ISO Lycopene inhibits the reaction [Atrazine results in increased expression of ATG7 mRNA] CTD PMID:30360616 NCBI chr 4:147,718,663...147,925,656
Ensembl chr 4:147,718,752...147,925,593
JBrowse link
G Atg9a autophagy related 9A multiple interactions ISO Lycopene inhibits the reaction [Atrazine results in increased expression of ATG9A mRNA] CTD PMID:30360616 NCBI chr 9:76,677,403...76,688,035
Ensembl chr 9:76,677,404...76,687,986
JBrowse link
G Atg9b autophagy related 9B multiple interactions ISO Lycopene inhibits the reaction [Atrazine results in increased expression of ATG9B mRNA] CTD PMID:30360616 NCBI chr 4:10,784,934...10,793,832
Ensembl chr 4:10,786,114...10,793,651
JBrowse link
G Atp1a1 ATPase Na+/K+ transporting subunit alpha 1 multiple interactions ISO Lycopene inhibits the reaction [Atrazine affects the expression of ATP1A1 mRNA]; Lycopene inhibits the reaction [Atrazine results in decreased expression of ATP1A1 mRNA]; Lycopene inhibits the reaction [Atrazine results in increased expression of ATP1A1 mRNA] CTD PMID:26476475 PMID:27112537 NCBI chr 2:189,020,722...189,048,826
Ensembl chr 2:189,020,722...189,048,837
JBrowse link
G Atp1a2 ATPase Na+/K+ transporting subunit alpha 2 multiple interactions ISO Lycopene inhibits the reaction [Atrazine results in decreased expression of ATP1A2 mRNA] CTD PMID:27112537 NCBI chr13:84,729,597...84,754,544
Ensembl chr13:84,729,601...84,754,544
JBrowse link
G Atp1a3 ATPase Na+/K+ transporting subunit alpha 3 multiple interactions ISO lycopene inhibits the reaction [Atrazine results in decreased expression of ATP1A3 mRNA] CTD PMID:26476475 NCBI chr 1:80,572,790...80,601,936
Ensembl chr 1:80,572,796...80,601,918
JBrowse link
G Atp1a4 ATPase Na+/K+ transporting subunit alpha 4 multiple interactions ISO Lycopene inhibits the reaction [Atrazine affects the expression of ATP1A4 mRNA] CTD PMID:26476475 PMID:27112537 NCBI chr13:84,683,766...84,719,790
Ensembl chr13:84,683,768...84,719,687
JBrowse link
G Atp1b1 ATPase Na+/K+ transporting subunit beta 1 multiple interactions ISO Lycopene inhibits the reaction [Atrazine results in decreased expression of ATP1B1 mRNA] CTD PMID:27112537 NCBI chr13:76,786,580...76,807,096
Ensembl chr13:76,786,578...76,807,459
JBrowse link
G Atp1b2 ATPase Na+/K+ transporting subunit beta 2 multiple interactions ISO Lycopene inhibits the reaction [Atrazine affects the expression of ATP1B2 mRNA] CTD PMID:26476475 PMID:27112537 NCBI chr10:54,318,698...54,324,933
Ensembl chr10:54,318,701...54,324,933
JBrowse link
G Atp1b3 ATPase Na+/K+ transporting subunit beta 3 multiple interactions ISO lycopene inhibits the reaction [Atrazine affects the expression of ATP1B3 mRNA] CTD PMID:26476475 NCBI chr 8:96,910,265...96,941,592
Ensembl chr 8:96,910,309...96,941,598
JBrowse link
G Atp1b4 ATPase Na+/K+ transporting family member beta 4 multiple interactions ISO lycopene inhibits the reaction [Atrazine results in increased expression of ATP1B4 mRNA] CTD PMID:26476475 NCBI chr  X:117,087,284...117,108,023
Ensembl chr  X:117,057,423...117,108,020
JBrowse link
G Atp2a1 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 1 multiple interactions ISO Lycopene inhibits the reaction [Atrazine affects the expression of ATP2A1 mRNA] CTD PMID:27112537 NCBI chr 1:181,026,606...181,044,859 JBrowse link
G Atp2a2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 multiple interactions ISO Lycopene inhibits the reaction [Atrazine affects the expression of ATP2A2 mRNA] CTD PMID:27112537 NCBI chr12:34,072,710...34,122,142
Ensembl chr12:34,072,683...34,122,101
JBrowse link
G Atp2a3 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3 multiple interactions ISO Lycopene inhibits the reaction [Atrazine results in decreased expression of ATP2A3 mRNA] CTD PMID:26476475 PMID:27112537 NCBI chr10:57,581,742...57,612,758
Ensembl chr10:57,582,128...57,612,748
JBrowse link
G Atp2b1 ATPase plasma membrane Ca2+ transporting 1 multiple interactions ISO Lycopene inhibits the reaction [Atrazine affects the expression of ATP2B1 mRNA]; Lycopene inhibits the reaction [Atrazine results in decreased expression of ATP2B1 mRNA] CTD PMID:26476475 PMID:27112537 NCBI chr 7:33,735,595...33,845,226
Ensembl chr 7:33,735,871...33,843,295
JBrowse link
G Atp2b2 ATPase plasma membrane Ca2+ transporting 2 multiple interactions ISO Lycopene inhibits the reaction [Atrazine results in decreased expression of ATP2B2 mRNA] CTD PMID:26476475 PMID:27112537 NCBI chr 4:146,896,332...147,140,665
Ensembl chr 4:146,896,332...147,140,665
JBrowse link
G Atp2b3 ATPase plasma membrane Ca2+ transporting 3 multiple interactions ISO Lycopene inhibits the reaction [Atrazine results in decreased expression of ATP2B3 mRNA] CTD PMID:26476475 PMID:27112537 NCBI chr  X:151,216,483...151,289,069
Ensembl chr  X:151,216,507...151,286,775
JBrowse link
G Atp2b4 ATPase plasma membrane Ca2+ transporting 4 multiple interactions ISO Lycopene inhibits the reaction [Atrazine affects the expression of ATP2B4 mRNA] CTD PMID:26476475 PMID:27112537 NCBI chr13:45,156,137...45,255,292
Ensembl chr13:45,156,146...45,255,246
JBrowse link
G Atp2c1 ATPase secretory pathway Ca2+ transporting 1 multiple interactions ISO Lycopene inhibits the reaction [Atrazine results in decreased expression of ATP2C1 mRNA] CTD PMID:26476475 PMID:27112537 NCBI chr 8:106,034,777...106,155,854
Ensembl chr 8:106,034,636...106,156,006
JBrowse link
G Atp2c2 ATPase secretory pathway Ca2+ transporting 2 multiple interactions ISO Lycopene inhibits the reaction [Atrazine affects the expression of ATP2C2 mRNA]; Lycopene inhibits the reaction [Atrazine results in decreased expression of ATP2C2 mRNA] CTD PMID:26476475 PMID:27112537 NCBI chr19:47,754,120...47,811,369
Ensembl chr19:47,754,120...47,811,368
JBrowse link
G Bach1 BTB domain and CNC homolog 1 increases expression ISO lycopene results in increased expression of BACH1 mRNA CTD PMID:16886892 NCBI chr11:26,939,429...26,974,876
Ensembl chr11:26,939,480...26,972,447
JBrowse link
G Bap1 Brca1 associated protein 1 increases expression ISO lycopene results in increased expression of BAP1 mRNA CTD PMID:16886892 NCBI chr16:6,446,709...6,455,535
Ensembl chr16:6,446,709...6,455,535
JBrowse link
G Bax BCL2 associated X, apoptosis regulator multiple interactions ISO
EXP
lycopene inhibits the reaction [Sodium Fluoride results in increased expression of BAX mRNA]
Lycopene inhibits the reaction [Benzo(a)pyrene results in increased expression of BAX mRNA]; Lycopene inhibits the reaction [Benzo(a)pyrene results in increased expression of BAX protein]; Lycopene inhibits the reaction [Sodium Fluoride results in increased expression of BAX mRNA]; Lycopene inhibits the reaction [Sodium Glutamate results in increased expression of BAX mRNA]
CTD PMID:26900785 PMID:27871895 PMID:31568845 NCBI chr 1:95,940,001...95,945,407
Ensembl chr 1:95,938,808...95,945,368
JBrowse link
G Bche butyrylcholinesterase multiple interactions EXP Lycopene inhibits the reaction [Sodium Glutamate results in increased activity of BCHE protein] CTD PMID:26900785 NCBI chr 2:158,308,674...158,401,148
Ensembl chr 2:158,307,584...158,401,148
JBrowse link
G Bcl2 BCL2, apoptosis regulator multiple interactions
increases expression
EXP
ISO
[S-allylcysteine co-treated with Lycopene] inhibits the reaction [[Methylnitronitrosoguanidine co-treated with Sodium Chloride] results in increased expression of BCL2 protein]; Lycopene inhibits the reaction [[Methylnitronitrosoguanidine co-treated with Sodium Chloride] results in increased expression of BCL2 protein]; Lycopene inhibits the reaction [Benzo(a)pyrene results in decreased expression of BCL2 mRNA]; Lycopene inhibits the reaction [Benzo(a)pyrene results in decreased expression of BCL2 protein]; Lycopene inhibits the reaction [Sodium Fluoride results in decreased expression of BCL2 mRNA]; Lycopene inhibits the reaction [Sodium Glutamate results in decreased expression of BCL2 mRNA]
Lycopene results in increased expression of BCL2 mRNA
lycopene inhibits the reaction [Sodium Fluoride results in decreased expression of BCL2 mRNA]
CTD PMID:16030430 PMID:26900785 PMID:27871895 PMID:31568845 NCBI chr13:22,689,783...22,853,920 JBrowse link
G Bco1 beta-carotene oxygenase 1 multiple interactions ISO BCO1 affects the reaction [lycopene results in decreased abundance of Testosterone] CTD PMID:21935922 NCBI chr19:45,149,250...45,186,102
Ensembl chr19:45,149,265...45,186,101
JBrowse link
G Bdnf brain-derived neurotrophic factor multiple interactions ISO
EXP
Lycopene inhibits the reaction [Galactose results in decreased expression of BDNF mRNA]; Lycopene inhibits the reaction [Galactose results in decreased expression of BDNF protein]
Lycopene inhibits the reaction [Oxaliplatin results in decreased expression of BDNF protein]
CTD PMID:28974442 PMID:32544411 NCBI chr 3:96,165,042...96,215,621
Ensembl chr 3:96,165,042...96,215,615
JBrowse link
G Becn1 beclin 1 multiple interactions ISO Lycopene inhibits the reaction [Atrazine results in increased expression of BECN1 mRNA] CTD PMID:30360616 NCBI chr10:86,231,387...86,246,742
Ensembl chr10:86,231,388...86,246,742
JBrowse link
G Braf B-Raf proto-oncogene, serine/threonine kinase decreases expression ISO lycopene results in decreased expression of BRAF protein CTD PMID:17337101 NCBI chr 4:68,375,484...68,510,652
Ensembl chr 4:68,384,649...68,510,463
JBrowse link
G C1qa complement C1q A chain decreases expression ISO lycopene results in decreased expression of C1QA mRNA CTD PMID:19555370 NCBI chr 5:149,133,635...149,136,482
Ensembl chr 5:149,133,636...149,136,534
JBrowse link
G C4b complement C4B (Chido blood group) decreases expression ISO lycopene results in decreased expression of C4B mRNA CTD PMID:19555370 NCBI chr20:4,197,371...4,211,684
Ensembl chr20:4,197,366...4,211,681
JBrowse link
G Calca calcitonin-related polypeptide alpha multiple interactions EXP Lycopene inhibits the reaction [Chlorodiphenyl (54% Chlorine) results in increased expression of CALCA protein] CTD PMID:33592256 NCBI chr 1:168,878,212...168,883,176
Ensembl chr 1:168,878,214...168,883,105
JBrowse link
G Casp3 caspase 3 multiple interactions EXP
ISO
[S-allylcysteine co-treated with Lycopene] inhibits the reaction [[Methylnitronitrosoguanidine co-treated with Sodium Chloride] results in decreased expression of CASP3 protein]; Lycopene inhibits the reaction [Atrazine results in increased expression of CASP3 mRNA]; Lycopene inhibits the reaction [Benzo(a)pyrene results in increased cleavage of CASP3 protein]; Lycopene inhibits the reaction [Oxaliplatin results in increased expression of CASP3 protein]; Lycopene inhibits the reaction [Sodium Fluoride results in increased activity of CASP3 protein]; Lycopene inhibits the reaction [Sodium Fluoride results in increased expression of CASP3 mRNA]
lycopene inhibits the reaction [Sodium Fluoride results in increased activity of CASP3 protein]; lycopene inhibits the reaction [Sodium Fluoride results in increased expression of CASP3 mRNA]
CTD PMID:16030430 PMID:27102619 PMID:27871895 PMID:31568845 PMID:32544411 NCBI chr16:45,662,910...45,681,171
Ensembl chr16:45,662,910...45,684,648
JBrowse link
G Casp8 caspase 8 multiple interactions
decreases expression
EXP
ISO
[S-allylcysteine co-treated with lycopene] inhibits the reaction [[Methylnitronitrosoguanidine co-treated with Sodium Chloride] results in decreased expression of CASP8 protein]; lycopene inhibits the reaction [[Methylnitronitrosoguanidine co-treated with Sodium Chloride] results in decreased expression of CASP8 protein]
lycopene results in decreased expression of CASP8 mRNA
CTD PMID:16030430 PMID:16886892 NCBI chr 9:60,263,863...60,312,542
Ensembl chr 9:60,264,075...60,312,542
JBrowse link
G Casp9 caspase 9 multiple interactions EXP
ISO
lycopene inhibits the reaction [Sodium Fluoride results in increased expression of CASP9 mRNA]
lycopene inhibits the reaction [Sodium Fluoride results in increased activity of CASP9 protein]; lycopene inhibits the reaction [Sodium Fluoride results in increased expression of CASP9 mRNA]
CTD PMID:27871895 NCBI chr 5:154,108,872...154,126,628
Ensembl chr 5:154,109,046...154,126,626
JBrowse link
G Cat catalase multiple interactions
decreases expression
increases activity
increases expression
EXP
ISO
Lycopene affects the reaction [Doxorubicin affects the activity of CAT protein]; Lycopene inhibits the reaction [Atrazine results in decreased activity of CAT protein]; Lycopene inhibits the reaction [Benzo(a)pyrene results in decreased activity of CAT protein]; Lycopene inhibits the reaction [Cadmium Chloride results in increased activity of CAT protein]; Lycopene inhibits the reaction [Mercuric Chloride results in increased activity of CAT protein]; Lycopene inhibits the reaction [Oxaliplatin results in decreased activity of CAT protein]; Lycopene inhibits the reaction [Sodium Glutamate results in increased activity of CAT protein]; Lycopene inhibits the reaction [Sodium Glutamate results in increased expression of CAT mRNA]
Lycopene results in decreased expression of CAT mRNA
Lycopene inhibits the reaction [Acetaminophen results in increased activity of CAT protein]; Lycopene inhibits the reaction [Atrazine results in decreased activity of CAT protein]
lycopene results in increased activity of CAT protein
lycopene results in increased expression of CAT
CTD PMID:16325981 PMID:17516994 PMID:17873360 PMID:19450652 PMID:20074268 More... NCBI chr 3:89,842,393...89,874,577
Ensembl chr 3:89,842,399...89,874,478
JBrowse link
G Ccnd1 cyclin D1 multiple interactions
decreases expression
ISO
EXP
lycopene inhibits the reaction [Genistein results in increased expression of CCND1 protein]; lycopene inhibits the reaction [IGF1 protein results in increased expression of CCND1 protein]
lycopene results in decreased expression of CCND1 protein
lycopene inhibits the reaction [[Dietary Fats co-treated with Diethylnitrosamine] results in increased expression of CCND1 protein]
CTD PMID:16565789 PMID:17051425 PMID:17337101 PMID:19551842 NCBI chr 1:200,089,002...200,098,524
Ensembl chr 1:200,089,002...200,098,602
JBrowse link
G Ccne1 cyclin E1 decreases expression
increases expression
ISO lycopene results in decreased expression of CCNE1 protein
lycopene results in increased expression of CCNE1 mRNA
CTD PMID:16886892 PMID:17337101 NCBI chr 1:90,781,947...90,791,188
Ensembl chr 1:90,781,949...90,791,101
JBrowse link
G Cdk1 cyclin-dependent kinase 1 decreases expression ISO lycopene results in decreased expression of CDK1 protein CTD PMID:17337101 NCBI chr20:19,266,226...19,281,417
Ensembl chr20:19,266,248...19,281,408
JBrowse link
G Cdk4 cyclin-dependent kinase 4 decreases expression ISO lycopene results in decreased expression of CDK4 protein CTD PMID:17337101 NCBI chr 7:62,885,647...62,889,562
Ensembl chr 7:62,883,105...62,942,403
JBrowse link
G Cdk5 cyclin-dependent kinase 5 decreases expression ISO lycopene results in decreased expression of CDK5 protein CTD PMID:17337101 NCBI chr 4:10,754,682...10,760,110
Ensembl chr 4:10,754,687...10,760,112
JBrowse link
G Cdk7 cyclin-dependent kinase 7 decreases expression ISO lycopene results in decreased expression of CDK7 protein CTD PMID:17337101 NCBI chr 2:31,840,545...31,865,447
Ensembl chr 2:31,840,558...31,865,383
JBrowse link
G Cdk9 cyclin-dependent kinase 9 decreases expression ISO lycopene results in decreased expression of CDK9 protein CTD PMID:17337101 NCBI chr 3:15,996,467...16,001,315
Ensembl chr 3:15,996,468...16,002,410
JBrowse link
G Cdkn1a cyclin-dependent kinase inhibitor 1A multiple interactions ISO lycopene inhibits the reaction [IGF1 protein results in increased expression of CDKN1A protein] CTD PMID:16565789 NCBI chr20:7,149,177...7,159,727
Ensembl chr20:7,149,217...7,159,585
JBrowse link
G Chga chromogranin A increases expression ISO lycopene results in increased expression of CHGA mRNA CTD PMID:16886892 NCBI chr 6:121,696,051...121,707,399
Ensembl chr 6:121,696,051...121,707,398
JBrowse link
G Chgb chromogranin B decreases expression ISO lycopene results in decreased expression of CHGB mRNA CTD PMID:16886892 NCBI chr 3:120,043,824...120,057,169
Ensembl chr 3:120,043,738...120,057,166
JBrowse link
G Ckb creatine kinase B multiple interactions EXP Lycopene inhibits the reaction [Sodium Glutamate results in increased activity of CKB protein] CTD PMID:26900785 NCBI chr 6:130,729,420...130,732,301
Ensembl chr 6:130,729,423...130,732,315
JBrowse link
G Crb1 crumbs cell polarity complex component 1 decreases expression ISO lycopene results in decreased expression of CRB1 mRNA CTD PMID:16886892 NCBI chr13:50,801,484...50,989,261
Ensembl chr13:50,800,959...50,989,261
JBrowse link
G Ctss cathepsin S decreases expression ISO lycopene results in decreased expression of CTSS mRNA CTD PMID:19555370 NCBI chr 2:183,089,192...183,114,483
Ensembl chr 2:183,086,437...183,114,483
JBrowse link
G Cxcl14 C-X-C motif chemokine ligand 14 decreases expression ISO lycopene results in decreased expression of CXCL14 mRNA CTD PMID:19555370 NCBI chr17:8,317,933...8,325,956
Ensembl chr17:8,317,933...8,324,839
JBrowse link
G Cyb5a cytochrome b5 type A multiple interactions ISO lycopene inhibits the reaction [Atrazine results in increased expression of CYB5A protein] CTD PMID:26775023 NCBI chr18:78,213,067...78,245,677
Ensembl chr18:78,202,342...78,258,535
Ensembl chr18:78,202,342...78,258,535
JBrowse link
G Cyp11a1 cytochrome P450, family 11, subfamily a, polypeptide 1 multiple interactions EXP lycopene inhibits the reaction [Chlorodiphenyl (54% Chlorine) results in decreased expression of CYP11A1 protein] CTD PMID:19071209 NCBI chr 8:58,422,807...58,434,342
Ensembl chr 8:58,404,669...58,434,338
JBrowse link
G Cyp1a1 cytochrome P450, family 1, subfamily a, polypeptide 1 decreases activity
multiple interactions
ISO lycopene results in decreased activity of CYP1A1 protein
lycopene inhibits the reaction [Atrazine results in increased expression of CYP1A1 mRNA]
CTD PMID:19329757 PMID:26775023 NCBI chr 8:58,096,021...58,102,130
Ensembl chr 8:58,096,077...58,102,125
JBrowse link
G Cyp1a2 cytochrome P450, family 1, subfamily a, polypeptide 2 multiple interactions ISO lycopene inhibits the reaction [Atrazine results in increased expression of CYP1A2 mRNA] CTD PMID:26775023 NCBI chr 8:58,075,367...58,082,255
Ensembl chr 8:58,075,367...58,082,312
JBrowse link
G Cyp1b1 cytochrome P450, family 1, subfamily b, polypeptide 1 decreases activity
multiple interactions
ISO lycopene results in decreased activity of CYP1B1 protein
lycopene affects the reaction [Atrazine results in increased expression of CYP1B1 mRNA]
CTD PMID:19329757 PMID:26775023 NCBI chr 6:15,342,312...15,350,886
Ensembl chr 6:15,342,344...15,350,917
JBrowse link
G Cyp21a1 cytochrome P450, family 21, subfamily a, polypeptide 1 decreases expression EXP lycopene results in decreased expression of CYP21A1 mRNA CTD PMID:15084515 NCBI chr20:4,020,217...4,026,923
Ensembl chr20:4,023,767...4,026,923
JBrowse link
G Cyp2b3 cytochrome P450, family 2, subfamily b, polypeptide 3 multiple interactions ISO lycopene affects the reaction [Atrazine results in increased expression of CYP2B9 mRNA] CTD PMID:26775023 NCBI chr 1:81,652,762...81,732,153
Ensembl chr 1:81,652,787...81,732,143
JBrowse link
G Cyp2e1 cytochrome P450, family 2, subfamily e, polypeptide 1 multiple interactions ISO lycopene inhibits the reaction [Atrazine results in increased expression of CYP2E1 mRNA] CTD PMID:26775023 NCBI chr 1:195,840,330...195,850,728
Ensembl chr 1:195,840,058...195,864,023
JBrowse link
G Cyp3a2 cytochrome P450, family 3, subfamily a, polypeptide 2 increases activity ISO Lycopene results in increased activity of CYP3A4 protein CTD PMID:16632523 NCBI chr12:9,207,986...9,230,038
Ensembl chr12:9,015,383...9,285,008
JBrowse link
G Cyp7b1 cytochrome P450 family 7 subfamily B member 1 multiple interactions ISO lycopene inhibits the reaction [Atrazine results in increased expression of CYP7B1 mRNA] CTD PMID:26775023 NCBI chr 2:100,502,791...100,669,713
Ensembl chr 2:100,502,791...100,669,698
JBrowse link
G Ddb2 damage specific DNA binding protein 2 increases expression ISO lycopene results in increased expression of DDB2 mRNA CTD PMID:16886892 NCBI chr 3:77,185,114...77,207,650
Ensembl chr 3:77,185,109...77,207,631
JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 multiple interactions EXP Lycopene inhibits the reaction [Oxaliplatin results in increased expression of EIF2AK3 mRNA] CTD PMID:32544411 NCBI chr 4:102,805,495...102,866,914
Ensembl chr 4:102,805,510...102,866,911
JBrowse link
G Eif4g1 eukaryotic translation initiation factor 4 gamma, 1 increases expression ISO lycopene results in increased expression of EIF4G1 mRNA CTD PMID:16886892 NCBI chr11:80,221,919...80,241,958
Ensembl chr11:80,221,919...80,241,941
JBrowse link
G Ern1 endoplasmic reticulum to nucleus signaling 1 multiple interactions EXP Lycopene inhibits the reaction [Oxaliplatin results in increased expression of ERN1 mRNA] CTD PMID:32544411 NCBI chr10:91,326,889...91,421,201
Ensembl chr10:91,330,654...91,421,029
JBrowse link
G Esr1 estrogen receptor 1 multiple interactions
increases expression
ISO lycopene inhibits the reaction [Estradiol results in increased activity of ESR1 protein]
lycopene results in increased expression of ESR1 mRNA
CTD PMID:16886892 PMID:17051425 NCBI chr 1:41,106,335...41,499,104
Ensembl chr 1:41,210,475...41,495,002
JBrowse link
G Esr2 estrogen receptor 2 multiple interactions ISO lycopene inhibits the reaction [Estradiol results in increased activity of ESR2 protein] CTD PMID:17051425 NCBI chr 6:94,858,438...94,909,630
Ensembl chr 6:94,809,547...94,908,919
JBrowse link
G Fancc FA complementation group C decreases expression ISO lycopene results in decreased expression of FANCC mRNA CTD PMID:16886892 NCBI chr17:1,680,660...1,822,610
Ensembl chr17:1,681,324...1,829,376
JBrowse link
G Fancf FA complementation group F decreases expression ISO lycopene results in decreased expression of FANCF mRNA CTD PMID:16886892 NCBI chr 1:101,449,120...101,452,361
Ensembl chr 1:101,450,389...101,451,923
JBrowse link
G Faslg Fas ligand decreases expression ISO lycopene results in decreased expression of FASLG mRNA CTD PMID:16886892 NCBI chr13:74,151,519...74,172,760
Ensembl chr13:74,154,954...74,162,215
JBrowse link
G Fos Fos proto-oncogene, AP-1 transcription factor subunit increases expression ISO lycopene results in increased expression of FOS mRNA CTD PMID:16886892 NCBI chr 6:105,121,170...105,124,036
Ensembl chr 6:105,121,170...105,124,036
JBrowse link
G Get1 guided entry of tail-anchored proteins factor 1 decreases expression ISO Lycopene results in decreased expression of GET1 mRNA CTD PMID:16886892 NCBI chr11:35,438,555...35,460,156
Ensembl chr11:35,445,815...35,459,973
JBrowse link
G Gfap glial fibrillary acidic protein decreases expression
multiple interactions
ISO
EXP
lycopene results in decreased expression of GFAP mRNA
Lycopene inhibits the reaction [Oxaliplatin results in increased expression of GFAP protein]
CTD PMID:19555370 PMID:32544411 NCBI chr10:87,852,891...87,861,631
Ensembl chr10:87,852,890...87,861,589
JBrowse link
G Gja1 gap junction protein, alpha 1 increases expression
multiple interactions
ISO
EXP
lycopene results in increased expression of GJA1 protein
Lycopene inhibits the reaction [Benzo(a)pyrene results in decreased expression of GJA1 protein]
CTD PMID:16091010 PMID:31568845 NCBI chr20:35,756,007...35,768,481
Ensembl chr20:35,755,991...35,768,582
JBrowse link
G Gja4 gap junction protein, alpha 4 decreases expression ISO lycopene results in decreased expression of GJA4 mRNA CTD PMID:16886892 NCBI chr 5:139,633,324...139,635,857
Ensembl chr 5:139,633,287...139,635,925
JBrowse link
G Gja5 gap junction protein, alpha 5 decreases expression
increases expression
ISO lycopene results in decreased expression of GJA5 mRNA
lycopene results in increased expression of GJA5 mRNA
CTD PMID:16886892 NCBI chr 2:184,602,407...184,621,952
Ensembl chr 2:184,564,475...184,621,952
JBrowse link
G Gpx4 glutathione peroxidase 4 decreases expression ISO lycopene results in decreased expression of GPX4 mRNA CTD PMID:16886892 NCBI chr 7:9,650,186...9,652,982
Ensembl chr 7:9,650,185...9,652,982
JBrowse link
G Gsr glutathione-disulfide reductase multiple interactions ISO lycopene inhibits the reaction [Zearalenone results in decreased activity of GSR protein] CTD PMID:25682699 NCBI chr16:58,482,209...58,525,256
Ensembl chr16:58,482,505...58,525,661
JBrowse link
G Hmgb1 high mobility group box 1 multiple interactions
decreases response to substance
ISO lycopene inhibits the reaction [HMGB1 protein results in increased expression of AGER protein]; lycopene inhibits the reaction [HMGB1 protein results in increased expression of and results in increased secretion of PLA2G2A protein]; lycopene inhibits the reaction [HMGB1 protein results in increased expression of and results in increased secretion of TNF protein]; lycopene inhibits the reaction [HMGB1 protein results in increased expression of ICAM1 mRNA]; lycopene inhibits the reaction [HMGB1 protein results in increased expression of ICAM1 protein]; lycopene inhibits the reaction [HMGB1 protein results in increased expression of SELE mRNA]; lycopene inhibits the reaction [HMGB1 protein results in increased expression of SELE protein]; lycopene inhibits the reaction [HMGB1 protein results in increased expression of TLR2 protein]; lycopene inhibits the reaction [HMGB1 protein results in increased expression of TLR4 protein]; lycopene inhibits the reaction [HMGB1 protein results in increased expression of VCAM1 mRNA]; lycopene inhibits the reaction [HMGB1 protein results in increased expression of VCAM1 protein]; lycopene inhibits the reaction [Lipopolysaccharides results in increased secretion of HMGB1 protein]
lycopene results in decreased susceptibility to HMGB1 protein
CTD PMID:22429818 NCBI chr12:5,973,062...5,978,565 JBrowse link
G Hmox1 heme oxygenase 1 increases expression
multiple interactions
EXP
ISO
lycopene results in increased expression of HMOX1 mRNA; lycopene results in increased expression of HMOX1 protein
Lycopene inhibits the reaction [Atrazine results in increased expression of HMOX1 mRNA]; Lycopene inhibits the reaction [Galactose results in decreased expression of HMOX1 mRNA]
[lycopene co-treated with Hydrogen Peroxide] results in increased expression of HMOX1 protein
lycopene promotes the reaction [Atrazine results in increased expression of HMOX1 mRNA]
CTD PMID:19551842 PMID:27102619 PMID:28974442 PMID:30360616 NCBI chr19:13,466,287...13,474,082
Ensembl chr19:13,467,244...13,474,079
JBrowse link
G Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 multiple interactions EXP lycopene inhibits the reaction [Chlorodiphenyl (54% Chlorine) results in decreased activity of HSD3B1 protein] CTD PMID:19071209 NCBI chr 2:186,169,864...186,175,984
Ensembl chr 2:186,169,863...186,175,999
JBrowse link
G Hspa4 heat shock protein family A (Hsp70) member 4 multiple interactions EXP lycopene inhibits the reaction [decamethrin results in increased expression of HSPA4 mRNA] CTD PMID:23076637 NCBI chr10:37,408,025...37,449,080
Ensembl chr10:37,408,025...37,449,001
JBrowse link
G Hspa5 heat shock protein family A (Hsp70) member 5 multiple interactions EXP Lycopene inhibits the reaction [Oxaliplatin results in increased expression of HSPA5 mRNA] CTD PMID:32544411 NCBI chr 3:18,055,507...18,059,969
Ensembl chr 3:18,055,405...18,059,891
JBrowse link
G Icam1 intercellular adhesion molecule 1 multiple interactions ISO [Ascorbic Acid co-treated with lycopene co-treated with alpha-Tocopherol] inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA]; lycopene inhibits the reaction [HMGB1 protein results in increased expression of ICAM1 mRNA]; lycopene inhibits the reaction [HMGB1 protein results in increased expression of ICAM1 protein]; lycopene inhibits the reaction [TNF protein results in increased expression of ICAM1 mRNA] CTD PMID:22429818 PMID:25551565 NCBI chr 8:19,553,063...19,565,438
Ensembl chr 8:19,553,645...19,565,438
JBrowse link
G Igf1 insulin-like growth factor 1 multiple interactions
decreases expression
increases expression
ISO
EXP
lycopene inhibits the reaction [IGF1 protein results in increased expression of CCND1 protein]; lycopene inhibits the reaction [IGF1 protein results in increased expression of CDKN1A protein]; lycopene inhibits the reaction [IGF1 protein results in increased phosphorylation of RB1 protein]
lycopene results in decreased expression of IGF1 mRNA
lycopene results in increased expression of IGF1 mRNA
CTD PMID:15084515 PMID:16565789 PMID:16886892 NCBI chr 7:22,282,895...22,361,972
Ensembl chr 7:22,282,930...22,359,296
JBrowse link
G Igf1r insulin-like growth factor 1 receptor decreases expression ISO lycopene results in decreased expression of IGF1R protein CTD PMID:17337101 NCBI chr 1:121,549,839...121,838,545
Ensembl chr 1:121,550,743...121,831,777
JBrowse link
G Igfbp2 insulin-like growth factor binding protein 2 increases expression ISO lycopene results in increased expression of IGFBP2 protein CTD PMID:17337101 NCBI chr 9:74,415,574...74,442,945
Ensembl chr 9:74,415,546...74,442,937
JBrowse link
G Il10 interleukin 10 multiple interactions ISO [Ascorbic Acid co-treated with lycopene co-treated with alpha-Tocopherol] promotes the reaction [TNF protein results in increased expression of and results in increased secretion of IL10 protein]; lycopene promotes the reaction [TNF protein results in increased expression of and results in increased secretion of IL10 protein]
lycopene inhibits the reaction [Zearalenone results in increased expression of IL10]
CTD PMID:25551565 PMID:25682699 NCBI chr13:42,472,625...42,477,308
Ensembl chr13:42,472,839...42,477,313