Map3k13 (mitogen-activated protein kinase kinase kinase 13) - Rat Genome Database

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Gene: Map3k13 (mitogen-activated protein kinase kinase kinase 13) Rattus norvegicus
Analyze
Symbol: Map3k13
Name: mitogen-activated protein kinase kinase kinase 13
RGD ID: 1561227
Description: Predicted to enable several functions, including IkappaB kinase complex binding activity; JUN kinase kinase kinase activity; and protein homodimerization activity. Predicted to be involved in several processes, including positive regulation of JUN kinase activity; positive regulation of cell projection organization; and protein phosphorylation. Predicted to be located in membrane. Orthologous to human MAP3K13 (mitogen-activated protein kinase kinase kinase 13); PARTICIPATES IN c-Jun N-terminal kinases MAPK signaling pathway; mitogen activated protein kinase signaling pathway; INTERACTS WITH (+)-schisandrin B; 2,3,7,8-tetrachlorodibenzodioxine; 6-propyl-2-thiouracil.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: leucine zipper-bearing kinase; LOC303823; similar to mitogen-activated protein kinase kinase kinase 13
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: mRatBN7.2 - mRatBN7.2 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21179,094,087 - 79,235,181 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1179,097,247 - 79,235,181 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1187,832,392 - 87,971,900 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.01180,486,036 - 80,625,546 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.01179,546,735 - 79,686,246 (-)NCBIRnor_WKY
Rnor_6.01182,744,391 - 82,938,357 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1182,745,735 - 82,938,357 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01185,830,850 - 85,865,109 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41181,327,515 - 81,467,415 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1177,956,031 - 78,091,697 (-)NCBICelera
Cytogenetic Map11q23NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Integrated genomic profiling and modelling for risk stratification in patients with advanced oesophagogastric adenocarcinoma. Hao D, etal., Gut. 2021 Nov;70(11):2055-2065. doi: 10.1136/gutjnl-2020-322707. Epub 2020 Dec 17.
3. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
4. GOA pipeline RGD automated data pipeline
5. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
6. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
7. Comprehensive gene review and curation RGD comprehensive gene curation
8. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
Additional References at PubMed
PMID:9353328   PMID:11163770   PMID:11726277   PMID:12492477   PMID:14690535   PMID:27511108  


Genomics

Comparative Map Data
Map3k13
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21179,094,087 - 79,235,181 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1179,097,247 - 79,235,181 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1187,832,392 - 87,971,900 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.01180,486,036 - 80,625,546 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.01179,546,735 - 79,686,246 (-)NCBIRnor_WKY
Rnor_6.01182,744,391 - 82,938,357 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1182,745,735 - 82,938,357 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01185,830,850 - 85,865,109 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41181,327,515 - 81,467,415 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
Celera1177,956,031 - 78,091,697 (-)NCBICelera
Cytogenetic Map11q23NCBI
MAP3K13
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh383185,282,961 - 185,489,094 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl3185,282,941 - 185,489,094 (+)EnsemblGRCh38hg38GRCh38
GRCh373185,000,749 - 185,206,882 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 363186,563,664 - 186,683,322 (+)NCBINCBI36Build 36hg18NCBI36
Build 343186,563,671 - 186,683,329NCBI
Celera3183,526,871 - 183,646,121 (+)NCBICelera
Cytogenetic Map3q27.2NCBI
HuRef3182,410,418 - 182,616,479 (+)NCBIHuRef
CHM1_13184,963,400 - 185,169,890 (+)NCBICHM1_1
T2T-CHM13v2.03188,098,494 - 188,304,852 (+)NCBIT2T-CHM13v2.0
Map3k13
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391621,643,923 - 21,752,189 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl1621,613,096 - 21,752,189 (+)EnsemblGRCm39 Ensembl
GRCm381621,824,056 - 21,933,439 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1621,794,346 - 21,933,439 (+)EnsemblGRCm38mm10GRCm38
MGSCv371621,892,042 - 21,931,950 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv361621,805,952 - 21,846,450 (+)NCBIMGSCv36mm8
Celera1622,459,094 - 22,498,899 (+)NCBICelera
Cytogenetic Map16B1NCBI
Map3k13
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542022,064,384 - 22,224,789 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542022,064,384 - 22,190,662 (-)NCBIChiLan1.0ChiLan1.0
MAP3K13
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.13190,875,284 - 190,993,633 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3190,798,694 - 190,993,633 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v03182,319,405 - 182,517,655 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
MAP3K13
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13418,081,158 - 18,252,800 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3418,083,595 - 18,247,367 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3422,196,773 - 22,338,512 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.03418,019,990 - 18,159,874 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl3417,990,427 - 18,159,873 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.13418,055,958 - 18,195,550 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.03418,051,916 - 18,191,465 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.03418,281,506 - 18,423,763 (+)NCBIUU_Cfam_GSD_1.0
Map3k13
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405602118,272,160 - 118,441,123 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049365784,368,900 - 4,532,966 (-)EnsemblSpeTri2.0
SpeTri2.0NW_0049365784,363,361 - 4,461,133 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MAP3K13
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13123,176,188 - 123,352,775 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113123,176,077 - 123,357,551 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213132,865,708 - 132,904,013 (+)NCBISscrofa10.2Sscrofa10.2susScr3
MAP3K13
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1153,947,464 - 4,135,554 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl153,947,851 - 4,138,194 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366606312,707,320 - 12,900,766 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Map3k13
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473071,161,646 - 71,312,442 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473071,162,598 - 71,313,369 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in Map3k13
527 total Variants
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:39
Count of miRNA genes:33
Interacting mature miRNAs:36
Transcripts:ENSRNOT00000035945
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (mRatBN7.2)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
724554Iddm17Insulin dependent diabetes mellitus QTL 170.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)111897620886241447Rat
724563Uae10Urinary albumin excretion QTL 106urine albumin amount (VT:0002871)urine albumin level (CMO:0000130)112767241082846715Rat
1300110Stl7Serum triglyceride level QTL 74.64blood triglyceride amount (VT:0002644)plasma triglyceride level (CMO:0000548)112952841882566702Rat
70180BpQTLcluster10Blood pressure QTL cluster 103.19arterial blood pressure trait (VT:2000000)mean arterial blood pressure (CMO:0000009)113491804179918041Rat
1300135Rf19Renal function QTL 193.38blood creatinine amount (VT:0005328)creatinine clearance (CMO:0000765)114094618882566702Rat
2312566Glom20Glomerulus QTL 203.60.001kidney glomerulus morphology trait (VT:0005325)index of glomerular damage (CMO:0001135)114428575982566702Rat
1581565Pur10Proteinuria QTL 100.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)114480331882846466Rat
1581572Uae35Urinary albumin excretion QTL 350.0001urine albumin amount (VT:0002871)urine albumin excretion rate (CMO:0000757)114480331882846466Rat
724561Plsm4Polydactyly-luxate syndrome (PLS) morphotypes QTL 40.0003forelimb integrity trait (VT:0010562)front foot phalanges count (CMO:0001947)115445753486241447Rat
4889521Gluco62Glucose level QTL 622.820.001blood glucose amount (VT:0000188)blood glucose level (CMO:0000046)115513672982993457Rat
7411658Foco27Food consumption QTL 2716.20.001eating behavior trait (VT:0001431)feed conversion ratio (CMO:0001312)115635142486241447Rat
631506Bp104Blood pressure QTL 1042.8arterial blood pressure trait (VT:2000000)systolic blood pressure (CMO:0000004)115980279482566545Rat
70208Niddm22Non-insulin dependent diabetes mellitus QTL 223.61blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)115980279482566553Rat
10058954Gmadr7Adrenal mass QTL 72.490.0049adrenal gland mass (VT:0010420)both adrenal glands wet weight to body weight ratio (CMO:0002411)116034659086241447Rat
1549848Bvd6Brain ventricular dilatation QTL 63.10.0001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)116611332182169223Rat
634339Niddm50Non-insulin dependent diabetes mellitus QTL 503.32blood glucose amount (VT:0000188)plasma glucose level (CMO:0000042)116642214886241447Rat
1354593Stl12Serum triglyceride level QTL 123.36blood triglyceride amount (VT:0002644)serum triglyceride level (CMO:0000360)116642214886241447Rat
1354656Bvd3Brain ventricular dilatation QTL 33.640.001brain ventricle morphology trait (VT:0000822)hydrocephalus severity score (CMO:0001881)116944607082846715Rat
10450831Scl80Serum cholesterol level QTL 804.70.01blood LDL cholesterol amount (VT:0000181)blood low density lipoprotein cholesterol level (CMO:0000053)117695713183051965Rat

Markers in Region
AW523989  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21179,219,459 - 79,219,629 (+)MAPPERmRatBN7.2
Rnor_6.01182,921,374 - 82,921,543NCBIRnor6.0
Rnor_5.01186,001,073 - 86,001,242UniSTSRnor5.0
RGSC_v3.41181,451,695 - 81,451,864UniSTSRGSC3.4
Celera1178,075,987 - 78,076,156UniSTS
RH 3.4 Map11654.4UniSTS
Cytogenetic Map11q23UniSTS
BE121163  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.21179,218,441 - 79,218,598 (+)MAPPERmRatBN7.2
Rnor_6.01182,920,356 - 82,920,512NCBIRnor6.0
Rnor_5.01186,000,055 - 86,000,211UniSTSRnor5.0
RGSC_v3.41181,450,677 - 81,450,833UniSTSRGSC3.4
Celera1178,074,969 - 78,075,125UniSTS
RH 3.4 Map11653.0UniSTS
Cytogenetic Map11q23UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system appendage
High
Medium 9 9 9 40 9
Low 3 38 48 32 19 32 2 2 34 26 41 11 2
Below cutoff 5 6 9 6

Sequence


Reference Sequences
RefSeq Acc Id: ENSRNOT00000035945   ⟹   ENSRNOP00000038786
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1179,097,247 - 79,235,181 (-)Ensembl
Rnor_6.0 Ensembl1182,747,538 - 82,938,357 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000078072   ⟹   ENSRNOP00000072235
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.0 Ensembl1182,745,735 - 82,783,328 (-)Ensembl
RefSeq Acc Id: ENSRNOT00000083539   ⟹   ENSRNOP00000071097
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl1179,109,137 - 79,159,961 (-)Ensembl
Rnor_6.0 Ensembl1182,759,284 - 82,810,014 (-)Ensembl
RefSeq Acc Id: NM_001013978   ⟹   NP_001014000
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21179,097,247 - 79,235,181 (-)NCBI
Rnor_6.01182,747,538 - 82,938,357 (-)NCBI
Rnor_5.01185,830,850 - 85,865,109 (-)NCBI
RGSC_v3.41181,327,515 - 81,467,415 (-)RGD
Celera1177,956,031 - 78,091,697 (-)RGD
Sequence:
RefSeq Acc Id: XM_017597976   ⟹   XP_017453465
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21179,094,087 - 79,183,328 (-)NCBI
Rnor_6.01182,744,391 - 82,833,687 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017597978   ⟹   XP_017453467
RefSeq Status:
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.21179,094,087 - 79,209,329 (-)NCBI
Rnor_6.01182,744,391 - 82,909,760 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001014000 (Get FASTA)   NCBI Sequence Viewer  
  XP_017453465 (Get FASTA)   NCBI Sequence Viewer  
  XP_017453467 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAH81976 (Get FASTA)   NCBI Sequence Viewer  
  AAO91624 (Get FASTA)   NCBI Sequence Viewer  
  EDL78039 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_001014000   ⟸   NM_001013978
- UniProtKB: F7FMK8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017453467   ⟸   XM_017597978
- Peptide Label: isoform X1
- UniProtKB: F7FMK8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017453465   ⟸   XM_017597976
- Peptide Label: isoform X1
- UniProtKB: F7FMK8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSRNOP00000038786   ⟸   ENSRNOT00000035945
RefSeq Acc Id: ENSRNOP00000072235   ⟸   ENSRNOT00000078072
RefSeq Acc Id: ENSRNOP00000071097   ⟸   ENSRNOT00000083539
Protein Domains
Protein kinase

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-F7FMK8-F1-model_v2 AlphaFold F7FMK8 1-958 view protein structure

Transcriptome

eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

Promoters
RGD ID:13698266
Promoter ID:EPDNEW_R8787
Type:multiple initiation site
Name:Map3k13_1
Description:mitogen-activated protein kinase kinase kinase 13
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.01182,938,346 - 82,938,406EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene RGD:1561227 AgrOrtholog
BioCyc Gene G2FUF-20792 BioCyc
Ensembl Genes ENSRNOG00000025423 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein ENSRNOP00000038786 ENTREZGENE
  ENSRNOP00000038786.5 UniProtKB/TrEMBL
  ENSRNOP00000071097.1 UniProtKB/TrEMBL
Ensembl Transcript ENSRNOT00000035945 ENTREZGENE
  ENSRNOT00000035945.7 UniProtKB/TrEMBL
  ENSRNOT00000083539.2 UniProtKB/TrEMBL
IMAGE_CLONE IMAGE:7127060 IMAGE-MGC_LOAD
InterPro Kinase-like_dom UniProtKB/TrEMBL
  MAP3K12_MAP3K13 UniProtKB/TrEMBL
  MAPKKK13 UniProtKB/TrEMBL
  Prot_kinase_cat_dom UniProtKB/TrEMBL
  Ser-Thr/Tyr_kinase_cat_dom UniProtKB/TrEMBL
  Ser/Thr_kinase_AS UniProtKB/TrEMBL
KEGG Report rno:303823 UniProtKB/TrEMBL
MGC_CLONE MGC:94134 IMAGE-MGC_LOAD
NCBI Gene 303823 ENTREZGENE
Pfam Pkinase_Tyr UniProtKB/TrEMBL
PhenoGen Map3k13 PhenoGen
PIRSF MAPKKK12_MAPKKK13 UniProtKB/TrEMBL
  MAPKKK13 UniProtKB/TrEMBL
PRINTS TYRKINASE UniProtKB/TrEMBL
PROSITE PROTEIN_KINASE_DOM UniProtKB/TrEMBL
  PROTEIN_KINASE_ST UniProtKB/TrEMBL
SMART S_TKc UniProtKB/TrEMBL
Superfamily-SCOP Kinase_like UniProtKB/TrEMBL
UniProt F7FMK8 ENTREZGENE, UniProtKB/TrEMBL
  Q66H82_RAT UniProtKB/TrEMBL


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2010-04-20 Map3k13  mitogen-activated protein kinase kinase kinase 13  LOC303823  similar to mitogen-activated protein kinase kinase kinase 13; leucine zipper-bearing kinase  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2006-02-09 LOC303823  similar to mitogen-activated protein kinase kinase kinase 13; leucine zipper-bearing kinase      Symbol and Name status set to provisional 70820 PROVISIONAL