MAP3K13 (mitogen-activated protein kinase kinase kinase 13) - Rat Genome Database

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Gene: MAP3K13 (mitogen-activated protein kinase kinase kinase 13) Sus scrofa
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Symbol: MAP3K13
Name: mitogen-activated protein kinase kinase kinase 13
RGD ID: 13846278
Description: ENCODES a protein that exhibits identical protein binding (ortholog); protein serine/threonine kinase activity (ortholog); INVOLVED IN JNK cascade (ortholog); protein phosphorylation (ortholog); PARTICIPATES IN c-Jun N-terminal kinases MAPK signaling pathway; ASSOCIATED WITH Currarino syndrome (ortholog); FOUND IN cytoplasm (inferred); membrane (inferred)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Latest Assembly: Sscrofa11.1 - Pig Sscrofa11.1 Assembly
Position:
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13123,176,188 - 123,352,775 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113123,176,077 - 123,357,551 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213132,865,708 - 132,904,013 (+)NCBISscrofa10.2Sscrofa10.2susScr3
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Genomics

Comparative Map Data
MAP3K13
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl13123,176,188 - 123,352,775 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.113123,176,077 - 123,357,551 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.213132,865,708 - 132,904,013 (+)NCBISscrofa10.2Sscrofa10.2susScr3
MAP3K13
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl3185,282,941 - 185,489,094 (+)EnsemblGRCh38hg38GRCh38
GRCh383185,282,938 - 185,489,094 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh373185,000,749 - 185,206,882 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 363186,563,664 - 186,683,322 (+)NCBINCBI36hg18NCBI36
Build 343186,563,671 - 186,683,329NCBI
Celera3183,526,871 - 183,646,121 (+)NCBI
Cytogenetic Map3q27.2NCBI
HuRef3182,410,418 - 182,616,479 (+)NCBIHuRef
CHM1_13184,963,400 - 185,169,890 (+)NCBICHM1_1
Map3k13
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm391621,643,923 - 21,752,189 (+)NCBIGRCm39mm39
GRCm39 Ensembl1621,613,096 - 21,752,189 (+)Ensembl
GRCm381621,824,056 - 21,933,439 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl1621,794,346 - 21,933,439 (+)EnsemblGRCm38mm10GRCm38
MGSCv371621,892,042 - 21,931,950 (+)NCBIGRCm37mm9NCBIm37
MGSCv361621,805,952 - 21,846,450 (+)NCBImm8
Celera1622,459,094 - 22,498,899 (+)NCBICelera
Cytogenetic Map16B1NCBI
Map3k13
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21179,094,087 - 79,235,181 (-)NCBI
Rnor_6.0 Ensembl1182,745,735 - 82,938,357 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01182,744,391 - 82,938,357 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01185,830,850 - 85,865,109 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41181,327,515 - 81,467,415 (-)NCBIRGSC3.4rn4RGSC3.4
Celera1177,956,031 - 78,091,697 (-)NCBICelera
Cytogenetic Map11q23NCBI
Map3k13
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542022,064,384 - 22,224,789 (-)EnsemblChiLan1.0
ChiLan1.0NW_00495542022,064,384 - 22,190,662 (-)NCBIChiLan1.0ChiLan1.0
MAP3K13
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.13190,875,284 - 190,993,633 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl3190,798,694 - 190,993,633 (+)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v03182,319,405 - 182,517,655 (+)NCBIMhudiblu_PPA_v0panPan3
MAP3K13
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.13418,081,158 - 18,252,800 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl3418,083,595 - 18,247,367 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha3422,196,773 - 22,338,512 (+)NCBI
ROS_Cfam_1.03418,019,990 - 18,159,874 (+)NCBI
UMICH_Zoey_3.13418,055,958 - 18,195,550 (+)NCBI
UNSW_CanFamBas_1.03418,051,916 - 18,191,465 (+)NCBI
UU_Cfam_GSD_1.03418,281,506 - 18,423,763 (+)NCBI
Map3k13
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024405602118,272,160 - 118,441,123 (-)NCBI
SpeTri2.0NW_0049365784,363,361 - 4,461,133 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
MAP3K13
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1153,947,464 - 4,135,554 (-)NCBI
ChlSab1.1 Ensembl153,947,851 - 4,138,194 (-)Ensembl
Vero_WHO_p1.0NW_02366606312,707,320 - 12,900,766 (-)NCBI
Map3k13
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473071,162,598 - 71,313,369 (-)NCBI


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system hemolymphoid system musculoskeletal system nervous system renal system reproductive system respiratory system
High
Medium 1 7 1 1
Low 10 4 2 5 2 16 1 2 3
Below cutoff

Sequence


Reference Sequences
RefSeq Acc Id: ENSSSCT00000012903   ⟹   ENSSSCP00000012562
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl13123,178,869 - 123,352,775 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000038300   ⟹   ENSSSCP00000053490
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl13123,176,188 - 123,352,775 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000042825   ⟹   ENSSSCP00000036091
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl13123,214,686 - 123,352,775 (+)Ensembl
RefSeq Acc Id: ENSSSCT00000062873   ⟹   ENSSSCP00000045573
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.1 Ensembl13123,176,188 - 123,352,775 (+)Ensembl
RefSeq Acc Id: XM_021069980   ⟹   XP_020925639
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.113123,176,077 - 123,357,551 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021069981   ⟹   XP_020925640
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.113123,249,741 - 123,357,551 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021069982   ⟹   XP_020925641
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.113123,212,607 - 123,357,551 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021069983   ⟹   XP_020925642
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.113123,212,607 - 123,357,551 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021069984   ⟹   XP_020925643
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.113123,212,607 - 123,357,551 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021069985   ⟹   XP_020925644
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.113123,253,463 - 123,357,551 (+)NCBI
Sequence:
RefSeq Acc Id: XM_021069986   ⟹   XP_020925645
RefSeq Status:
Type: CODING
Position:
Pig AssemblyChrPosition (strand)Source
Sscrofa11.113123,249,741 - 123,357,551 (+)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: XP_020925639   ⟸   XM_021069980
- Sequence:
RefSeq Acc Id: XP_020925641   ⟸   XM_021069982
- Sequence:
RefSeq Acc Id: XP_020925643   ⟸   XM_021069984
- Sequence:
RefSeq Acc Id: XP_020925642   ⟸   XM_021069983
- Sequence:
RefSeq Acc Id: XP_020925645   ⟸   XM_021069986
- Sequence:
RefSeq Acc Id: XP_020925640   ⟸   XM_021069981
- Sequence:
RefSeq Acc Id: XP_020925644   ⟸   XM_021069985
- Sequence:
RefSeq Acc Id: ENSSSCP00000036091   ⟸   ENSSSCT00000042825
RefSeq Acc Id: ENSSSCP00000012562   ⟸   ENSSSCT00000012903
RefSeq Acc Id: ENSSSCP00000053490   ⟸   ENSSSCT00000038300
RefSeq Acc Id: ENSSSCP00000045573   ⟸   ENSSSCT00000062873
Protein Domains
Protein kinase


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSSSCG00000011791 Ensembl, ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCG00070017074 UniProtKB/TrEMBL
Ensembl Protein ENSSSCP00000012562 UniProtKB/TrEMBL
  ENSSSCP00000036091 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCP00000045573 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCP00000053490 UniProtKB/TrEMBL
  ENSSSCP00070028131 UniProtKB/TrEMBL
  ENSSSCP00070028139 UniProtKB/TrEMBL
  ENSSSCP00070028140 UniProtKB/TrEMBL
  ENSSSCP00070028146 UniProtKB/TrEMBL
Ensembl Transcript ENSSSCT00000012903 UniProtKB/TrEMBL
  ENSSSCT00000038300 UniProtKB/TrEMBL
  ENSSSCT00000042825 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCT00000062873 ENTREZGENE, UniProtKB/TrEMBL
  ENSSSCT00070033704 UniProtKB/TrEMBL
  ENSSSCT00070033713 UniProtKB/TrEMBL
  ENSSSCT00070033714 UniProtKB/TrEMBL
  ENSSSCT00070033720 UniProtKB/TrEMBL
InterPro Kinase-like_dom_sf UniProtKB/TrEMBL
  MAP3K12_MAP3K13 UniProtKB/TrEMBL
  MAPKKK13 UniProtKB/TrEMBL
  Prot_kinase_dom UniProtKB/TrEMBL
  Ser-Thr/Tyr_kinase_cat_dom UniProtKB/TrEMBL
  Ser/Thr_kinase_AS UniProtKB/TrEMBL
NCBI Gene MAP3K13 ENTREZGENE
Pfam Pkinase_Tyr UniProtKB/TrEMBL
PIRSF MAPKKK12_MAPKKK13 UniProtKB/TrEMBL
  MAPKKK13 UniProtKB/TrEMBL
PRINTS TYRKINASE UniProtKB/TrEMBL
PROSITE PROTEIN_KINASE_DOM UniProtKB/TrEMBL
  PROTEIN_KINASE_ST UniProtKB/TrEMBL
SMART S_TKc UniProtKB/TrEMBL
Superfamily-SCOP SSF56112 UniProtKB/TrEMBL
UniProt A0A286ZX99_PIG UniProtKB/TrEMBL
  A0A287ANR6_PIG UniProtKB/TrEMBL
  A0A287BBN8_PIG UniProtKB/TrEMBL
  A0A4X1UDS9_PIG UniProtKB/TrEMBL
  A0A4X1UHV4_PIG UniProtKB/TrEMBL
  F1SG70_PIG UniProtKB/TrEMBL