Dmtn (dematin actin binding protein)

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Gene: Dmtn (dematin actin binding protein) Rattus norvegicus

Analyze

Symbol:

Dmtn

Name:

dematin actin binding protein

RGD ID:

1311419

Description:

Predicted to enable cytoskeletal protein binding activity; protein self-association; and signaling receptor binding activity. Predicted to be involved in several processes, including calcium-mediated signaling; negative regulation of protein phosphorylation; and regulation of cell-substrate adhesion. Predicted to be located in several cellular components, including cytoskeleton; platelet dense tubular network membrane; and postsynaptic density. Predicted to be active in actin cytoskeleton and plasma membrane. Orthologous to human DMTN (dematin actin binding protein); INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; bisphenol A.

Type:

protein-coding

RefSeq Status:

VALIDATED

Previously known as:

dematin; Epb4.9; Epb49; erythrocyte membrane protein band 4.9; erythrocyte membrane protein band 4.9 (dematin); erythrocyte protein band 4.9; LOC361069

RGD Orthologs

Human

Mouse

Chinchilla

Bonobo

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

More Info

Species	Gene symbol and name	Data Source	Assertion derived from	less info ...
Orthologs ¹				less info ...
Homo sapiens (human):	DMTN (dematin actin binding protein)	HGNC	Ensembl, HomoloGene, NCBI, OMA, OrthoDB, Panther
Mus musculus (house mouse):	Dmtn (dematin actin binding protein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chinchilla lanigera (long-tailed chinchilla):	Dmtn (dematin actin binding protein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Pan paniscus (bonobo/pygmy chimpanzee):	DMTN (dematin actin binding protein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Canis lupus familiaris (dog):	DMTN (dematin actin binding protein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Ictidomys tridecemlineatus (thirteen-lined ground squirrel):	Dmtn (dematin actin binding protein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Sus scrofa (pig):	DMTN (dematin actin binding protein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Chlorocebus sabaeus (green monkey):	DMTN (dematin actin binding protein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Heterocephalus glaber (naked mole-rat):	Dmtn (dematin actin binding protein)	Transitive Ortholog Pipeline	Transitive Ortholog Pipeline
Alliance orthologs ³
Homo sapiens (human):	DMTN (dematin actin binding protein)	Alliance	DIOPT (Ensembl Compara\|HGNC\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Mus musculus (house mouse):	Dmtn (dematin actin binding protein)	Alliance	DIOPT (Hieranoid\|InParanoid\|OMA\|OrthoFinder\|OrthoInspector\|PANTHER\|PhylomeDB\|SonicParanoid)
Danio rerio (zebrafish):	dmtn (dematin actin binding protein)	Alliance	DIOPT (Ensembl Compara\|Hieranoid\|InParanoid\|OMA\|OrthoFinder\|PANTHER\|SonicParanoid)

Latest Assembly:

mRatBN7.2 - mRatBN7.2 Assembly

Position:

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	15	45,677,974 - 45,705,601 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	15	45,677,977 - 45,705,601 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	15	49,795,828 - 49,820,113 (-)	NCBI	Rnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0	15	50,907,337 - 50,931,630 (-)	NCBI	Rnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0	15	47,766,648 - 47,790,933 (-)	NCBI	Rnor_WKY
Rnor_6.0	15	52,292,762 - 52,320,385 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	15	52,292,765 - 52,320,385 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	15	56,016,279 - 56,043,902 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	15	51,004,498 - 51,032,118 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	15	51,021,363 - 51,047,921 (-)	NCBI
Celera	15	45,356,046 - 45,383,646 (-)	NCBI		Celera
Cytogenetic Map	15	p11	NCBI

JBrowse:

View Region in Genome Browser (JBrowse)

Model

Annotation Click to see Annotation Detail View

Disease Annotations Click to see Annotation Detail View

Conotruncal Cardiac Defects (ISO)

genetic disease (ISO)

Gene-Chemical Interaction Annotations Click to see Annotation Detail View

1,1-dichloroethene (ISO)

1,2-dimethylhydrazine (ISO)

17alpha-ethynylestradiol (ISO)

17beta-estradiol (EXP,ISO)

2,3,7,8-tetrachlorodibenzodioxine (EXP,ISO)

2-butoxyethanol (ISO)

3,3',5,5'-tetrabromobisphenol A (ISO)

3,3',5-triiodo-L-thyronine (ISO)

3-phenylprop-2-enal (ISO)

4,4'-sulfonyldiphenol (ISO)

4-hydroxyphenyl retinamide (ISO)

aflatoxin B1 (ISO)

aldehydo-D-glucose (ISO)

atrazine (ISO)

benzo[a]pyrene (ISO)

benzo[b]fluoranthene (ISO)

bisphenol A (EXP,ISO)

bromobenzene (EXP)

butanal (ISO)

C60 fullerene (EXP)

cadmium atom (ISO)

cadmium dichloride (ISO)

caffeine (ISO)

CGP 52608 (ISO)

chlorpyrifos (EXP)

cyclosporin A (ISO)

D-glucose (ISO)

diazinon (ISO)

dioxygen (ISO)

doxorubicin (ISO)

ethanol (ISO)

fucoxanthin (ISO)

gentamycin (EXP)

glucose (ISO)

lead(0) (ISO)

lead(2+) (ISO)

leflunomide (EXP)

N-methyl-4-phenylpyridinium (EXP)

nitrofen (EXP)

oxaliplatin (EXP)

paracetamol (EXP,ISO)

paraquat (EXP)

phenobarbital (ISO)

phenytoin (EXP)

pirinixic acid (ISO)

potassium dichromate (ISO)

silicon dioxide (ISO)

sodium arsenite (EXP,ISO)

sunitinib (ISO)

tamoxifen (ISO)

tetrachloromethane (EXP)

thioacetamide (EXP)

topotecan (EXP)

trichloroethene (EXP)

trimellitic anhydride (ISO)

triptonide (ISO)

urethane (ISO)

valproic acid (ISO)

vancomycin (ISO)

Gene Ontology Annotations Click to see Annotation Detail View

Biological Process

actin cytoskeleton organization (ISO)

actin filament bundle assembly (IBA,ISO)

actin filament reorganization (ISO)

calcium-mediated signaling using extracellular calcium source (ISO)

calcium-mediated signaling using intracellular calcium source (ISO)

cellular response to calcium ion (ISO)

cellular response to cAMP (ISO)

erythrocyte development (ISO)

lamellipodium assembly (IBA)

negative regulation of cell-substrate adhesion (ISO)

negative regulation of focal adhesion assembly (ISO)

negative regulation of peptidyl-serine phosphorylation (ISO)

negative regulation of peptidyl-threonine phosphorylation (ISO)

negative regulation of peptidyl-tyrosine phosphorylation (ISO)

negative regulation of protein targeting to membrane (ISO)

negative regulation of substrate adhesion-dependent cell spreading (ISO)

positive regulation of blood coagulation (ISO)

positive regulation of fibroblast migration (ISO)

positive regulation of integrin-mediated signaling pathway (ISO)

positive regulation of platelet aggregation (ISO)

positive regulation of substrate adhesion-dependent cell spreading (ISO)

positive regulation of wound healing (ISO)

protein secretion by platelet (ISO)

protein-containing complex assembly (ISO)

regulation of actin cytoskeleton organization (ISO)

regulation of cell shape (ISO)

regulation of filopodium assembly (ISO)

regulation of lamellipodium assembly (ISO)

Cellular Component

actin cytoskeleton (IBA)

actin filament (ISO)

cell projection membrane (ISO)

cortical cytoskeleton (ISO)

cytoplasmic vesicle (ISO)

cytosol (ISO)

membrane (ISO)

perinuclear region of cytoplasm (ISO)

plasma membrane (IBA,ISO)

platelet dense tubular network membrane (ISO)

postsynaptic density (ISO)

spectrin-associated cytoskeleton (ISO)

Molecular Function

actin binding (ISO)

actin filament binding (IBA)

protein binding (ISO)

protein self-association (ISO)

signaling receptor binding (ISO)

spectrin binding (ISO)

References

References - curated

#	Reference Title	Reference Citation
1.	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.	Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2.	Rat ISS GO annotations from GOA human gene data--August 2006	GOA data from the GO Consortium
3.	Rat ISS GO annotations from MGI mouse gene data--August 2006	MGD data from the GO Consortium
4.	GOA pipeline	RGD automated data pipeline
5.	Data Import for Chemical-Gene Interactions	RGD automated import pipeline for gene-chemical interactions

Additional References at PubMed

PMID:10565303	PMID:12011427	PMID:12477932	PMID:17114649	PMID:18347014	PMID:18505823	PMID:18723693	PMID:19241372	PMID:22927433	PMID:23060452	PMID:23355471

Genomics

Comparative Map Data

Dmtn
(Rattus norvegicus - Norway rat)

Rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
mRatBN7.2	15	45,677,974 - 45,705,601 (-)	NCBI	mRatBN7.2	mRatBN7.2
mRatBN7.2 Ensembl	15	45,677,977 - 45,705,601 (-)	Ensembl		mRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx	15	49,795,828 - 49,820,113 (-)	NCBI	Rnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0	15	50,907,337 - 50,931,630 (-)	NCBI	Rnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0	15	47,766,648 - 47,790,933 (-)	NCBI	Rnor_WKY
Rnor_6.0	15	52,292,762 - 52,320,385 (-)	NCBI	Rnor6.0	Rnor_6.0	rn6	Rnor6.0
Rnor_6.0 Ensembl	15	52,292,765 - 52,320,385 (-)	Ensembl	Rnor6.0		rn6	Rnor6.0
Rnor_5.0	15	56,016,279 - 56,043,902 (-)	NCBI	Rnor5.0	Rnor_5.0	rn5	Rnor5.0
RGSC_v3.4	15	51,004,498 - 51,032,118 (-)	NCBI	RGSC3.4	RGSC_v3.4	rn4	RGSC3.4
RGSC_v3.1	15	51,021,363 - 51,047,921 (-)	NCBI
Celera	15	45,356,046 - 45,383,646 (-)	NCBI		Celera
Cytogenetic Map	15	p11	NCBI

DMTN
(Homo sapiens - human)

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38	8	22,048,931 - 22,082,525 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh38.p13 Ensembl	8	22,048,995 - 22,082,527 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh37	8	21,906,442 - 21,940,036 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	8	21,972,680 - 21,995,982 (+)	NCBI	NCBI36	Build 36	hg18	NCBI36
Build 34	8	21,972,679 - 21,995,982	NCBI
Celera	8	20,873,144 - 20,902,318 (+)	NCBI		Celera
Cytogenetic Map	8	p21.3	NCBI
HuRef	8	20,453,493 - 20,482,734 (+)	NCBI		HuRef
CHM1_1	8	22,112,744 - 22,141,695 (+)	NCBI		CHM1_1
T2T-CHM13v2.0	8	22,322,887 - 22,356,487 (+)	NCBI		T2T-CHM13v2.0

Dmtn
(Mus musculus - house mouse)

Mouse Assembly	Chr	Position (strand)	Source	Genome Browsers
Mouse Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCm39	14	70,839,624 - 70,873,488 (-)	NCBI	GRCm39	GRCm39	mm39
GRCm39 Ensembl	14	70,838,703 - 70,873,488 (-)	Ensembl		GRCm39 Ensembl
GRCm38	14	70,602,184 - 70,636,048 (-)	NCBI	GRCm38	GRCm38	mm10	GRCm38
GRCm38.p6 Ensembl	14	70,601,263 - 70,636,048 (-)	Ensembl	GRCm38		mm10	GRCm38
MGSCv37	14	71,003,477 - 71,029,961 (-)	NCBI	GRCm37	MGSCv37	mm9	NCBIm37
MGSCv36	14	69,338,750 - 69,365,234 (-)	NCBI		MGSCv36	mm8
Celera	14	68,145,198 - 68,173,371 (-)	NCBI		Celera
Cytogenetic Map	14	D2	NCBI
cM Map	14	36.32	NCBI

Dmtn
(Chinchilla lanigera - long-tailed chinchilla)

Chinchilla Assembly	Chr	Position (strand)	Source	Genome Browsers
Chinchilla Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChiLan1.0 Ensembl	NW_004955403	45,566,180 - 45,578,079 (+)	Ensembl	ChiLan1.0
ChiLan1.0	NW_004955403	45,566,180 - 45,579,062 (+)	NCBI	ChiLan1.0	ChiLan1.0

DMTN
(Pan paniscus - bonobo/pygmy chimpanzee)

Bonobo Assembly	Chr	Position (strand)	Source	Genome Browsers
Bonobo Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
PanPan1.1	8	18,238,541 - 18,267,291 (+)	NCBI	panpan1.1	PanPan1.1	panPan2
PanPan1.1 Ensembl	8	18,251,886 - 18,266,229 (+)	Ensembl	panpan1.1		panPan2
Mhudiblu_PPA_v0	8	21,293,759 - 21,327,600 (+)	NCBI	Mhudiblu_PPA_v0	Mhudiblu_PPA_v0	panPan3

DMTN
(Canis lupus familiaris - dog)

Dog Assembly	Chr	Position (strand)	Source	Genome Browsers
Dog Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
CanFam3.1	25	35,163,867 - 35,188,761 (-)	NCBI	CanFam3.1	CanFam3.1	canFam3	CanFam3.1
CanFam3.1 Ensembl	25	35,165,876 - 35,176,754 (-)	Ensembl	CanFam3.1		canFam3	CanFam3.1
Dog10K_Boxer_Tasha	25	35,752,999 - 35,778,392 (-)	NCBI		Dog10K_Boxer_Tasha
ROS_Cfam_1.0	25	35,374,965 - 35,400,383 (-)	NCBI		ROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl	25	35,375,297 - 35,400,794 (-)	Ensembl		ROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1	25	35,320,204 - 35,345,608 (-)	NCBI		UMICH_Zoey_3.1
UNSW_CanFamBas_1.0	25	35,177,036 - 35,200,175 (-)	NCBI		UNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0	25	35,332,536 - 35,355,698 (-)	NCBI		UU_Cfam_GSD_1.0

Dmtn
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)

Squirrel Assembly	Chr	Position (strand)	Source	Genome Browsers
Squirrel Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HiC_Itri_2	NW_024404943	12,659,342 - 12,685,809 (-)	NCBI		HiC_Itri_2
SpeTri2.0 Ensembl	NW_004936555	5,896,471 - 5,910,098 (+)	Ensembl	SpeTri2.0
SpeTri2.0	NW_004936555	5,884,746 - 5,911,171 (+)	NCBI	SpeTri2.0	SpeTri2.0		SpeTri2.0

DMTN
(Sus scrofa - pig)

Pig Assembly	Chr	Position (strand)	Source	Genome Browsers
Pig Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
Sscrofa11.1 Ensembl	14	6,321,870 - 6,346,865 (+)	Ensembl	Sscrofa11.1		susScr11	Sscrofa11.1
Sscrofa11.1	14	6,315,643 - 6,346,722 (+)	NCBI	Sscrofa11.1	Sscrofa11.1	susScr11	Sscrofa11.1
Sscrofa10.2	14	6,757,571 - 6,788,163 (+)	NCBI	Sscrofa10.2	Sscrofa10.2	susScr3

DMTN
(Chlorocebus sabaeus - green monkey)

Green Monkey Assembly	Chr	Position (strand)	Source	Genome Browsers
Green Monkey Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
ChlSab1.1	8	20,120,054 - 20,154,368 (+)	NCBI	ChlSab1.1	ChlSab1.1	chlSab2
ChlSab1.1 Ensembl	8	20,125,703 - 20,152,985 (+)	Ensembl	ChlSab1.1	ChlSab1.1 Ensembl	chlSab2
Vero_WHO_p1.0	NW_023666052	22,082,446 - 22,116,979 (-)	NCBI	Vero_WHO_p1.0	Vero_WHO_p1.0

Dmtn
(Heterocephalus glaber - naked mole-rat)

Naked Mole-rat Assembly	Chr	Position (strand)	Source	Genome Browsers
Naked Mole-rat Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
HetGla_female_1.0 Ensembl	NW_004624758	17,655,803 - 17,671,666 (+)	Ensembl	HetGla_female_1.0	HetGla_female_1.0 Ensembl	hetGla2
HetGla 1.0	NW_004624758	17,640,938 - 17,672,709 (+)	NCBI	HetGla_female_1.0	HetGla 1.0	hetGla2

Variants

Variants in Dmtn
30 total Variants

miRNA Target Status

Predicted Target Of

	Summary Value
Count of predictions:	524
Count of miRNA genes:	201
Interacting mature miRNAs:	260
Transcripts:	ENSRNOT00000016555, ENSRNOT00000067776
Prediction methods:	Miranda, Rnahybrid, Targetscan
Result types:	miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

QTLs in Region (mRatBN7.2)

The following QTLs overlap with this region.

RGD ID	Symbol	Name	LOD	P Value	Trait	Sub Trait	Chr	Start	Stop	Species
2298549	Neuinf12	Neuroinflammation QTL 12	3.5		nervous system integrity trait (VT:0010566)	spinal cord beta-2 microglobulin mRNA level (CMO:0002125)	15	1	55302115	Rat
738017	Hcas7	Hepatocarcinoma susceptibility QTL 7	2.91		liver integrity trait (VT:0010547)	liver nonremodeling tumorous lesion volume to total liver volume ratio (CMO:0001464)	15	2266368	46921453	Rat
1582251	Gluco24	Glucose level QTL 24	3.2	0.0008	blood glucose amount (VT:0000188)	blood glucose level (CMO:0000046)	15	5530756	50530756	Rat
631273	Lecl2	Lens clarity QTL 2		0.001	lens clarity trait (VT:0001304)	age of onset/diagnosis of cataract (CMO:0001584)	15	10596089	55596089	Rat
2300167	Bmd63	Bone mineral density QTL 63	5.9	0.0001	femur mineral mass (VT:0010011)	volumetric bone mineral density (CMO:0001553)	15	11111142	56111142	Rat
2300173	Bmd62	Bone mineral density QTL 62	12.8	0.0001	lumbar vertebra mineral mass (VT:0010511)	volumetric bone mineral density (CMO:0001553)	15	11111142	56111142	Rat
2293688	Bss29	Bone structure and strength QTL 29	5.31	0.0001	femur morphology trait (VT:0000559)	femur midshaft cortical cross-sectional area (CMO:0001663)	15	11111142	56111142	Rat
2317750	Glom26	Glomerulus QTL 26	4.3		urine protein amount (VT:0005160)	urine protein level (CMO:0000591)	15	12496141	65205939	Rat
61424	Scl1	Serum cholesterol level QTL 1	7.7	0.001	blood cholesterol amount (VT:0000180)	serum total cholesterol level (CMO:0000363)	15	16725528	80672115	Rat
1331729	Rf42	Renal function QTL 42	3.071		kidney blood vessel physiology trait (VT:0100012)	absolute change in renal blood flow rate (CMO:0001168)	15	17362897	73690657	Rat
2324620	Coatc3	Coat color QTL 3			coat/hair pigmentation trait (VT:0010463)	pigmented coat/hair area to total coat/hair area ratio (CMO:0001810)	15	19856566	46187442	Rat
10054130	Srcrt8	Stress Responsive Cort QTL 8	2.18	0.0085	blood corticosterone amount (VT:0005345)	plasma corticosterone level (CMO:0001173)	15	22117933	67117933	Rat
1578646	Bmd18	Bone mineral density QTL 18	5.2		femur mineral mass (VT:0010011)	trabecular volumetric bone mineral density (CMO:0001729)	15	22806240	98288169	Rat
1578647	Bmd17	Bone mineral density QTL 17	4		femur mineral mass (VT:0010011)	total volumetric bone mineral density (CMO:0001728)	15	22806240	98288169	Rat
1578660	Bss19	Bone structure and strength QTL 19	4.3		femur morphology trait (VT:0000559)	bone trabecular cross-sectional area (CMO:0002311)	15	22806240	98288169	Rat
1582214	Stl21	Serum triglyceride level QTL 21	3.1	0.022	blood triglyceride amount (VT:0002644)	serum triglyceride level (CMO:0000360)	15	28030665	82262678	Rat
1582227	Gluco30	Glucose level QTL 30	3.6	0.0003	blood glucose amount (VT:0000188)	absolute change in blood glucose level area under curve (CMO:0002034)	15	28030665	82262678	Rat
1582228	Epfw3	Epididymal fat weight QTL 3	4.1	0.0002	epididymal fat pad mass (VT:0010421)	epididymal fat pad weight to body weight ratio (CMO:0000658)	15	28030665	82262678	Rat
1582242	Gluco28	Glucose level QTL 28	3.3	0.0008	blood glucose amount (VT:0000188)	blood glucose level area under curve (AUC) (CMO:0000350)	15	28030665	82262678	Rat
1582244	Bw79	Body weight QTL 79	4	0.0002	epididymal fat pad mass (VT:0010421)	epididymal fat pad weight to body weight ratio (CMO:0000658)	15	28030665	82262678	Rat
2293691	Bmd37	Bone mineral density QTL 37	6.6	0.0001	femur strength trait (VT:0010010)	femur total energy absorbed before break (CMO:0001677)	15	33611058	71477291	Rat
2293686	Bmd36	Bone mineral density QTL 36	7.4	0.0001	femur strength trait (VT:0010010)	femoral neck ultimate force (CMO:0001703)	15	33611058	71477291	Rat
1598828	Glom14	Glomerulus QTL 14	2.5		kidney glomerulus morphology trait (VT:0005325)	index of glomerular damage (CMO:0001135)	15	34054139	79054139	Rat
7411725	Strs7	Sensitivity to stroke QTL 7	3.8		cerebrum integrity trait (VT:0010549)	percentage of study population developing cerebrovascular lesions during a period of time (CMO:0000932)	15	40289901	49308583	Rat
2306968	Anxrr23	Anxiety related response QTL 23	4.83		reflex trait (VT:0001961)	amplitude of the acoustic startle response (CMO:0001520)	15	40631268	46187442	Rat
1300144	Rf23	Renal function QTL 23	3.61		renal blood flow trait (VT:2000006)	absolute change in renal vascular resistance (CMO:0001900)	15	40631268	98288169	Rat

Markers in Region

RH129121

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	15	45,677,976 - 45,678,154 (+)	MAPPER	mRatBN7.2
Rnor_6.0	15	52,292,765 - 52,292,942	NCBI	Rnor6.0
Rnor_5.0	15	56,016,282 - 56,016,459	UniSTS	Rnor5.0
RGSC_v3.4	15	51,004,498 - 51,004,675	UniSTS	RGSC3.4
Celera	15	45,356,046 - 45,356,223	UniSTS
Cytogenetic Map	15	p11	UniSTS

AU047935

Rat Assembly	Chr	Position (strand)	Source	JBrowse
mRatBN7.2	15	45,702,516 - 45,702,737 (+)	MAPPER	mRatBN7.2
Rnor_6.0	15	52,317,303 - 52,317,521	NCBI	Rnor6.0
Rnor_5.0	15	56,040,820 - 56,041,038	UniSTS	Rnor5.0
RGSC_v3.4	15	51,029,036 - 51,029,254	UniSTS	RGSC3.4
Celera	15	45,380,564 - 45,380,782	UniSTS
Cytogenetic Map	15	p11	UniSTS

Expression

RNA-SEQ Expression

High: > 1000 TPM value Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM Below Cutoff: < 0.5 TPM

	alimentary part of gastrointestinal system	circulatory system	endocrine system	exocrine system	hemolymphoid system	hepatobiliary system	integumental system	musculoskeletal system	nervous system	renal system	reproductive system	respiratory system	appendage
High
Medium		8	22	22	8	22			64	35	18	3
Low	3	35	34	19	10	19	5	6	10		23	8	5
Below cutoff			1		1		3	5					3

View RNA-SEQ Expression Data

Sequence

Nucleotide Sequences


RefSeq Transcripts	NM_001108385	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001394746	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001394747	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	NM_001394748	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_006252281	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017599746	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	XM_017599747	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
GenBank Nucleotide	BC166453	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	CH473951	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	FQ235213	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles
	JACYVU010000272	(Get FASTA)	NCBI Sequence Viewer	Search GEO for Microarray Profiles

Reference Sequences

RefSeq Acc Id:

ENSRNOT00000016555 ⟹ ENSRNOP00000016555

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	15	45,677,977 - 45,702,433 (-)	Ensembl
Rnor_6.0 Ensembl	15	52,292,765 - 52,317,219 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000067776 ⟹ ENSRNOP00000059386

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	15	45,677,977 - 45,705,601 (-)	Ensembl
Rnor_6.0 Ensembl	15	52,292,765 - 52,320,385 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000097002 ⟹ ENSRNOP00000084709

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	15	45,677,977 - 45,704,833 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000106565 ⟹ ENSRNOP00000097697

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	15	45,677,977 - 45,704,833 (-)	Ensembl

RefSeq Acc Id:

ENSRNOT00000113196 ⟹ ENSRNOP00000093095

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2 Ensembl	15	45,679,382 - 45,693,827 (-)	Ensembl

RefSeq Acc Id:

NM_001108385 ⟹ NP_001101855

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	15	45,677,977 - 45,705,601 (-)	NCBI
Rnor_6.0	15	52,292,765 - 52,320,385 (-)	NCBI
Rnor_5.0	15	56,016,279 - 56,043,902 (-)	NCBI
RGSC_v3.4	15	51,004,498 - 51,032,118 (-)	RGD
Celera	15	45,356,046 - 45,383,646 (-)	RGD

Sequence:

show sequence

GGGCCACAGTCCTCTCAGGAAGTGTGGCACCAGTAACCTTTGTGGAAAAAGTAGCCCAGAAGTA
GATGTCTGGGCCTGGAACCCTCTTTCTTCCAGAGGTAAGAGTGACCATCCTCTGTGGGAATTGC
TAATGCCAATTCACAAGACCTGAGAGCTTCCAAAGCGCGGCTGGGTTCCTGGAGGAGCTGCCTC
TTACCTAGATTCCTGAGAAAACGCCGAAAACCCGTGGACCAGGGCCTAGGCCCTTTGCCTCTTG
GGGCTTCAGAGAGCCTGGGCCCCACTGTCTGGGAGGAGCCACCCGCGGTCAACAGCGCAGAGAG
GCCCAAGGGATGAGGACACCACAGAGCGTTGTGAAGCCCTCGCTGCAGGAGCCGGGCCGAGCCT
GACGTCTGTCCTCTCCACGTGCGCACCGGCTTCCGAGGGAGCGGCCGGCCAGTGGCTGCCGCAT
GGAACGTCTGCAGAAGCAACCTCTTACCTCCCCGGGGAGCGTCAGCTCCTCCAGAGACTCCAGT
GTACCCGGCTCTCCCTCCAACATCGTGGCCAAGATGGACAACCAGGTGTTGGGCTACAAAGACC
TGGCCGCCATCCCCAAGGACAAGGCCATCCTGGACATTGAGAGACCTGACCTCATGATCTACGA
GCCCCATTTTACCTATTCCCTCCTGGAACACGTAGAGCTTCCCAGAAGTCGGGAGTGCTCACTG
TCACCCAAATCCACATCCCCACCACCTTCTCCAGAGGTGTGGGCGGAGAGCCGGACACTTGGAA
TCATCTCTCAGGCTTCAACACCAAGGACCACAGGAACCCCCAGGACCAGCCTGCCCCATTTCCA
CCACCCTGAGACTACCCGCCCGGATTCCAACATCTACAAGAAGCCACCCATCTACAAGCAGAGA
GAATCGGTGGGAGGCAGCCCTCAGAGCAAGCACCTCATCGAGGACCTCATCATTGAGTCATCCA
AGTTCCCAGCAGCACAGCCCCCTGATCCCAACCAGCCAGCCAAGATAGAGACTGACTATTGGCC
GTGTCCCCCGTCGCTGGCTGTTGTGGAGACAGAATGGAGGAAGCGGAAGGCATCTCGAAAGGGC
GCAGAGGAAGAGGAGGAGGAGGAAGATGATGACTCTGAAGAGGAGATTAAGGCCATCAGGGAGC
GGCAGAAAGAGGAACTCAGTAAGGTTACTTCCAACTTGGGAAAGATGATCTTGAAAGAAGAGAT
GGAAAAGTCATTGCCCATCCGGAGGAAAACGCGCTCTCTGCCTGACCGGACACCCTTCCATACC
TCCTTGCATTCGGGAACGTCTAAGTCCTCGTCCCTTCCTTCCTATGGCAGGACCACCCTGAGTC
GGCTACAGTCCACAGAATTCAGCCCATCCGGAAGTGAGGCTGGGAGCCCAGATCTATCCCTATG
AGATGCTGGTGGTGACCAACAAGGGGAGAACTAAGCTGCCTCCCGGTGTGGACCGCATGAGGCT
TGAGAGGCATTTGTCAGCAGAGGACTTCTCTAGGGTCTTCGCCATGTCTCCTGAGGAGTTTGGC
AAGCTGGCCCTGTGGAAGCGGAACGAACTCAAGAAGAAAGCTTCCCTCTTCTGACATCCCTGCC
AGCTCGCCCTGTCCCCGTGACAGTACCTTCCTTCTGCTGCTTGAGGCCCTGAAGCTGGGGCTGT
GAGACCCCACAGTGACTCCTCTTCCTCTGCTGGCTGGGAGCAGCAGGAGGCTGGGCCTAAGTGT
CAGGCTCCACTCCTCAGGGAGAGAGCCAAGAAGTGCACAGTCCCAGAGTCATGAGGCATGGACT
TCCTTCCCCACGATGGGCCAGGGGGCCTTACCTTTTCCCTGGGCTCCACTGCCTAGCCAAACCC
AGTCCAGACTCCAGCACACAGTCAATGTTTGCACCCATTTCCTGTCTGTCACCCCACATGAGGG
TCCCCAGGAGACAGTGAGGAGAAATGAAGGGAGTTTAGTGGAGAGGTCTGTCTGCTATCCTGTA
CAGGGGGAGGCAGCAGCTCTGGGACCCTGTGCCTGTCTACCCAAAGGCTCCAGCCAGTTGCACT
CCTGACAGCTTCCTGCACTCAGGCCCGATGCTTCTCTAACTGGCAGAAGCAGGCTCTACCTGGG
CCTCCAGGTGGGAGGTCATCCTCCCTCTAGCTTATATGTCCTGTTCTTTGCAACCCCTAAGCTT
CAAACGTCTTGCTCGAGACCAGAGCTCATTCAAAGCTCTGGCTAAGAGCAGAGACGCTATTCAC
ACGACGCCTCACCACCACCAGCCTCCAGGCAAAACCAGATAGACTGCACCCTTCTATCACCTGT
CCAGGGACCACAGAGCCCAGGCCTCAGCCTCCCTTACATGGGACTAAGAGACCTAGCTTGGGGC
ATCTCTGAGAGTTCAGGCTCCCAGGTCCCTCCTCCGTTTGCTGTGCATCTCCTACTGTGCTCTC
TACAGAATGTAATTTATTGGGGCACCCTCTGCTGCTTCCTTTCCCTGACTCCTTGCCCTACCTA
ATTGCACTTCCAGTCCTGTCTGTCCACATATGTACATGTATATAATTATACATATATATATATA
TATCTATTTTGCCCAGATCTGGGTTTCGTTTTTACCCAGACCCCGGCACTCCCTGTCCACTGTG
TGTGAGATCATACTAGGAGGGGTAACTGCTTGGAATTAAAAGGTTGCACTGGGTCCCT

hide sequence

RefSeq Acc Id:

XM_006252281 ⟹ XP_006252343

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	15	45,677,974 - 45,694,138 (-)	NCBI
Rnor_6.0	15	52,292,762 - 52,308,874 (-)	NCBI
Rnor_5.0	15	56,016,279 - 56,043,902 (-)	NCBI

Sequence:

show sequence

GCCGAGCCTGACGTCTGTCCTCTCCACGTGCGCACCGGCTTCCGAGGGAGCGGCCGGCCAGTGG
CTGCCGCATGGAACGTCTGCAGAAGGCCAAGATGGACAACCAGGTGTTGGGCTACAAAGACCTG
GCCGCCATCCCCAAGGACAAGGCCATCCTGGACATTGAGAGACCTGACCTCATGATCTACGAGC
CCCATTTTACCTATTCCCTCCTGGAACACGTAGAGCTTCCCAGAAGTCGGGAGTGCTCACTGTC
ACCCAAATCCACATCCCCACCACCTTCTCCAGAGGTGTGGGCGGAGAGCCGGACACTTGGAATC
ATCTCTCAGGCTTCAACACCAAGGACCACAGGAACCCCCAGGACCAGCCTGCCCCATTTCCACC
ACCCTGAGACTACCCGCCCGGATTCCAACATCTACAAGAAGCCACCCATCTACAAGCAGAGAGA
ATCGGTGGGAGGCAGCCCTCAGAGCAAGCACCTCATCGAGGACCTCATCATTGAGTCATCCAAG
TTCCCAGCAGCACAGCCCCCTGATCCCAACCAGCCAGCCAAGATAGAGACTGACTATTGGCCGT
GTCCCCCGTCGCTGGCTGTTGTGGAGACAGAATGGAGGAAGCGGAAGGCATCTCGAAAGGGCGC
AGAGGAAGAGGAGGAGGAGGAAGATGATGACTCTGAAGAGGAGATTAAGGCCATCAGGGAGCGG
CAGAAAGAGGAACTCAGTAAGGTTACTTCCAACTTGGGAAAGATGATCTTGAAAGAAGAGATGG
AAAAGTCATTGCCCATCCGGAGGAAAACGCGCTCTCTGCCTGACCGGACACCCTTCCATACCTC
CTTGCATTCGGGAACGTCTAAGTCCTCGTCCCTTCCTTCCTATGGCAGGACCACCCTGAGTCGG
CTACAGTCCACAGAATTCAGCCCATCCGGAAGTGAGGCTGGGAGCCCAGGCCTGCAGAACGGAG
AGGGCCAGAGGGGGAGGATGGATCGGGGGAACTCCCTGCCCTGTGTGCTGGAGCAGAAGATCTA
TCCCTATGAGATGCTGGTGGTGACCAACAAGGGGAGAACTAAGCTGCCTCCCGGTGTGGACCGC
ATGAGGCTTGAGAGGCATTTGTCAGCAGAGGACTTCTCTAGGGTCTTCGCCATGTCTCCTGAGG
AGTTTGGCAAGCTGGCCCTGTGGAAGCGGAACGAACTCAAGAAGAAAGCTTCCCTCTTCTGACA
TCCCTGCCAGCTCGCCCTGTCCCCGTGACAGTACCTTCCTTCTGCTGCTTGAGGCCCTGAAGCT
GGGGCTGTGAGACCCCACAGTGACTCCTCTTCCTCTGCTGGCTGGGAGCAGCAGGAGGCTGGGC
CTAAGTGTCAGGCTCCACTCCTCAGGGAGAGAGCCAAGAAGTGCACAGTCCCAGAGTCATGAGG
CATGGACTTCCTTCCCCACGATGGGCCAGGGGGCCTTACCTTTTCCCTGGGCTCCACTGCCTAG
CCAAACCCAGTCCAGACTCCAGCACACAGTCAATGTTTGCACCCATTTCCTGTCTGTCACCCCA
CATGAGGGTCCCCAGGAGACAGTGAGGAGAAATGAAGGGAGTTTAGTGGAGAGGTCTGTCTGCT
ATCCTGTACAGGGGGAGGCAGCAGCTCTGGGACCCTGTGCCTGTCTACCCAAAGGCTCCAGCCA
GTTGCACTCCTGACAGCTTCCTGCACTCAGGCCCGATGCTTCTCTAACTGGCAGAAGCAGGCTC
TACCTGGGCCTCCAGGTGGGAGGTCATCCTCCCTCTAGCTTATATGTCCTGTTCTTTGCAACCC
CTAAGCTTCAAACGTCTTGCTCGAGACCAGAGCTCATTCAAAGCTCTGGCTAAGAGCAGAGACG
CTATTCACACGACGCCTCACCACCACCAGCCTCCAGGCAAAACCAGATAGACTGCACCCTTCTA
TCACCTGTCCAGGGACCACAGAGCCCAGGCCTCAGCCTCCCTTACATGGGACTAAGAGACCTAG
CTTGGGGCATCTCTGAGAGTTCAGGCTCCCAGGTCCCTCCTCCGTTTGCTGTGCATCTCCTACT
GTGCTCTCTACAGAATGTAATTTATTGGGGCACCCTCTGCTGCTTCCTTTCCCTGACTCCTTGC
CCTACCTAATTGCACTTCCAGTCCTGTCTGTCCACATATGTACATGTATATAATTATACATATA
TATATATATATCTATTTTGCCCAGATCTGGGTTTCGTTTTTACCCAGACCCCGGCACTCCCTGT
CCACTGTGTGTGAGATCATACTAGGAGGGGTAACTGCTTGGAATTAAAAGGTTGCACTGGGTCC
CTAAA

hide sequence

RefSeq Acc Id:

XM_017599746 ⟹ XP_017455235

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	15	45,677,974 - 45,702,261 (-)	NCBI
Rnor_6.0	15	52,292,762 - 52,308,878 (-)	NCBI

Sequence:

show sequence

CCGGGCCGAGCCTGACGTCTGTCCTCTCCACGTGCGCACCGGCTTCCGAGGGAGCGGCCGGCCA
GTGGCTGCCGCATGGAACGTCTGCAGAAGCAACCTCTTACCTCCCCGGGGAGCGTCAGCTCCTC
CAGAGACTCCAGTGTACCCGGCTCTCCCTCCAACATCGTGGCCAAGATGGACAACCAGGTGTTG
GGCTACAAAGACCTGGCCGCCATCCCCAAGGACAAGGCCATCCTGGACATTGAGAGACCTGACC
TCATGATCTACGAGCCCCATTTTACCTATTCCCTCCTGGAACACGTAGAGCTTCCCAGAAGTCG
GGAGTGCTCACTGTCACCCAAATCCACATCCCCACCACCTTCTCCAGAGGTGTGGGCGGAGAGC
CGGACACTTGGAATCATCTCTCAGGCTTCAACACCAAGGACCACAGGAACCCCCAGGACCAGCC
TGCCCCATTTCCACCACCCTGAGACTACCCGCCCGGATTCCAACATCTACAAGAAGCCACCCAT
CTACAAGCAGAGAGAATCGGTGGGAGGCAGCCCTCAGAGCAAGCACCTCATCGAGGACCTCATC
ATTGAGTCATCCAAGTTCCCAGCAGCACAGCCCCCTGATCCCAACCAGCCAGCCAAGATAGAGA
CTGACTATTGGCCGTGTCCCCCGTCGCTGGCTGTTGTGGAGACAGAATGGAGGAAGCGGAAGGC
ATCTCGAAAGGGCGCAGAGGAAGAGGAGGAGGAGGAAGATGATGACTCTGAAGAGGAGATTAAG
GCCATCAGGGAGCGGCAGAAAGAGGAACTCAGTAAGGTTACTTCCAACTTGGGAAAGATGATCT
TGAAAGAAGAGATGGAAAAGTCATTGCCCATCCGGAGGAAAACGCGCTCTCTGCCTGACCGGAC
ACCCTTCCATACCTCCTTGCATTCGGGAACGTCTAAGTCCTCGTCCCTTCCTTCCTATGGCAGG
ACCACCCTGAGTCGGCTACAGTCCACAGAATTCAGCCCATCCGGAAGTGAGGCTGGGAGCCCAG
GCCTGCAGAACGGAGAGGGCCAGAGGGGGAGGATGGATCGGGGGAACTCCCTGCCCTGTGTGCT
GGAGCAGAAGATCTATCCCTATGAGATGCTGGTGGTGACCAACAAGGGGAGAACTAAGCTGCCT
CCCGGTGTGGACCGCATGAGGCTTGAGAGGCATTTGTCAGCAGAGGACTTCTCTAGGGTCTTCG
CCATGTCTCCTGAGGAGTTTGGCAAGCTGGCCCTGTGGAAGCGGAACGAACTCAAGAAGAAAGC
TTCCCTCTTCTGACATCCCTGCCAGCTCGCCCTGTCCCCGTGACAGTACCTTCCTTCTGCTGCT
TGAGGCCCTGAAGCTGGGGCTGTGAGACCCCACAGTGACTCCTCTTCCTCTGCTGGCTGGGAGC
AGCAGGAGGCTGGGCCTAAGTGTCAGGCTCCACTCCTCAGGGAGAGAGCCAAGAAGTGCACAGT
CCCAGAGTCATGAGGCATGGACTTCCTTCCCCACGATGGGCCAGGGGGCCTTACCTTTTCCCTG
GGCTCCACTGCCTAGCCAAACCCAGTCCAGACTCCAGCACACAGTCAATGTTTGCACCCATTTC
CTGTCTGTCACCCCACATGAGGGTCCCCAGGAGACAGTGAGGAGAAATGAAGGGAGTTTAGTGG
AGAGGTCTGTCTGCTATCCTGTACAGGGGGAGGCAGCAGCTCTGGGACCCTGTGCCTGTCTACC
CAAAGGCTCCAGCCAGTTGCACTCCTGACAGCTTCCTGCACTCAGGCCCGATGCTTCTCTAACT
GGCAGAAGCAGGCTCTACCTGGGCCTCCAGGTGGGAGGTCATCCTCCCTCTAGCTTATATGTCC
TGTTCTTTGCAACCCCTAAGCTTCAAACGTCTTGCTCGAGACCAGAGCTCATTCAAAGCTCTGG
CTAAGAGCAGAGACGCTATTCACACGACGCCTCACCACCACCAGCCTCCAGGCAAAACCAGATA
GACTGCACCCTTCTATCACCTGTCCAGGGACCACAGAGCCCAGGCCTCAGCCTCCCTTACATGG
GACTAAGAGACCTAGCTTGGGGCATCTCTGAGAGTTCAGGCTCCCAGGTCCCTCCTCCGTTTGC
TGTGCATCTCCTACTGTGCTCTCTACAGAATGTAATTTATTGGGGCACCCTCTGCTGCTTCCTT
TCCCTGACTCCTTGCCCTACCTAATTGCACTTCCAGTCCTGTCTGTCCACATATGTACATGTAT
ATAATTATACATATATATATATATATCTATTTTGCCCAGATCTGGGTTTCGTTTTTACCCAGAC
CCCGGCACTCCCTGTCCACTGTGTGTGAGATCATACTAGGAGGGGTAACTGCTTGGAATTAAAA
GGTTGCACTGGGTCCCTAAA

hide sequence

RefSeq Acc Id:

XM_017599747 ⟹ XP_017455236

RefSeq Status:

Type:

CODING

Position:

Rat Assembly	Chr	Position (strand)	Source
mRatBN7.2	15	45,677,974 - 45,702,261 (-)	NCBI
Rnor_6.0	15	52,292,762 - 52,308,878 (-)	NCBI

Sequence:

show sequence

CCGGGCCGAGCCTGACGTCTGTCCTCTCCACGTGCGCACCGGCTTCCGAGGGAGCGGCCGGCCA
GTGGCTGCCGCATGGAACGTCTGCAGAAGCAACCTCTTACCTCCCCGGGGAGCGTCAGCTCCTC
CAGAGACTCCAGTGTACCCGGCTCTCCCTCCAACATCGTGGCCAAGATGGACAACCAGGTGTTG
GGCTACAAAGACCTGGCCGCCATCCCCAAGGACAAGGCCATCCTGGACATTGAGAGACCTGACC
TCATGATCTACGAGCCCCATTTTACCTATTCCCTCCTGGAACACGTAGAGCTTCCCAGAAGTCG
GGAGTGCTCACTGTCACCCAAATCCACATCCCCACCACCTTCTCCAGAGGTGTGGGCGGAGAGC
CGGACACTTGGAATCATCTCTCAGGCTTCAACACCAAGGACCACAGGAACCCCCAGGACCAGCC
TGCCCCATTTCCACCACCCTGAGACTACCCGCCCGGATTCCAACATCTACAAGAAGCCACCCAT
CTACAAGCAGAGAGAATCGGTGGGAGGCAGCCCTCAGAGCAAGCACCTCATCGAGGACCTCATC
ATTGAGTCATCCAAGTTCCCAGCAGCACAGCCCCCTGATCCCAACCAGCCAGCCAAGATAGAGA
CTGACTATTGGCCGTGTCCCCCGTCGCTGGCTGTTGTGGAGACAGAATGGAGGAAGCGGAAGGC
ATCTCGAAAGGGCGCAGAGGAAGAGGAGGAGGAGGAAGATGATGACTCTGAAGAGGAGATTAAG
GCCATCAGGGAGCGGCAGAAAGAGGAACTCAGTAAGGTTACTTCCAACTTGGGAAAGATGATCT
TGAAAGAAGAGATGGAAAAGTCATTGCCCATCCGGAGGAAAACGCGCTCTCTGCCTGACCGGAC
ACCCTTCCATACCTCCTTGCATTCGGGAACGTCTAAGTCCTCGTCCCTTCCTTCCTATGGCAGG
ACCACCCTGAGTCGGCTACAGTCCACAGAATTCAGCCCATCCGGAAGTGAGGCTGGGAGCCCAG
GCCTGCAGATCTATCCCTATGAGATGCTGGTGGTGACCAACAAGGGGAGAACTAAGCTGCCTCC
CGGTGTGGACCGCATGAGGCTTGAGAGGCATTTGTCAGCAGAGGACTTCTCTAGGGTCTTCGCC
ATGTCTCCTGAGGAGTTTGGCAAGCTGGCCCTGTGGAAGCGGAACGAACTCAAGAAGAAAGCTT
CCCTCTTCTGACATCCCTGCCAGCTCGCCCTGTCCCCGTGACAGTACCTTCCTTCTGCTGCTTG
AGGCCCTGAAGCTGGGGCTGTGAGACCCCACAGTGACTCCTCTTCCTCTGCTGGCTGGGAGCAG
CAGGAGGCTGGGCCTAAGTGTCAGGCTCCACTCCTCAGGGAGAGAGCCAAGAAGTGCACAGTCC
CAGAGTCATGAGGCATGGACTTCCTTCCCCACGATGGGCCAGGGGGCCTTACCTTTTCCCTGGG
CTCCACTGCCTAGCCAAACCCAGTCCAGACTCCAGCACACAGTCAATGTTTGCACCCATTTCCT
GTCTGTCACCCCACATGAGGGTCCCCAGGAGACAGTGAGGAGAAATGAAGGGAGTTTAGTGGAG
AGGTCTGTCTGCTATCCTGTACAGGGGGAGGCAGCAGCTCTGGGACCCTGTGCCTGTCTACCCA
AAGGCTCCAGCCAGTTGCACTCCTGACAGCTTCCTGCACTCAGGCCCGATGCTTCTCTAACTGG
CAGAAGCAGGCTCTACCTGGGCCTCCAGGTGGGAGGTCATCCTCCCTCTAGCTTATATGTCCTG
TTCTTTGCAACCCCTAAGCTTCAAACGTCTTGCTCGAGACCAGAGCTCATTCAAAGCTCTGGCT
AAGAGCAGAGACGCTATTCACACGACGCCTCACCACCACCAGCCTCCAGGCAAAACCAGATAGA
CTGCACCCTTCTATCACCTGTCCAGGGACCACAGAGCCCAGGCCTCAGCCTCCCTTACATGGGA
CTAAGAGACCTAGCTTGGGGCATCTCTGAGAGTTCAGGCTCCCAGGTCCCTCCTCCGTTTGCTG
TGCATCTCCTACTGTGCTCTCTACAGAATGTAATTTATTGGGGCACCCTCTGCTGCTTCCTTTC
CCTGACTCCTTGCCCTACCTAATTGCACTTCCAGTCCTGTCTGTCCACATATGTACATGTATAT
AATTATACATATATATATATATATCTATTTTGCCCAGATCTGGGTTTCGTTTTTACCCAGACCC
CGGCACTCCCTGTCCACTGTGTGTGAGATCATACTAGGAGGGGTAACTGCTTGGAATTAAAAGG
TTGCACTGGGTCCCTAAA

hide sequence

Protein Sequences


Protein RefSeqs	NP_001101855	(Get FASTA)	NCBI Sequence Viewer
	NP_001381675	(Get FASTA)	NCBI Sequence Viewer
	NP_001381676	(Get FASTA)	NCBI Sequence Viewer
	NP_001381677	(Get FASTA)	NCBI Sequence Viewer
	XP_006252343	(Get FASTA)	NCBI Sequence Viewer
	XP_017455235	(Get FASTA)	NCBI Sequence Viewer
	XP_017455236	(Get FASTA)	NCBI Sequence Viewer
GenBank Protein	AAI66453	(Get FASTA)	NCBI Sequence Viewer
	EDM02235	(Get FASTA)	NCBI Sequence Viewer
	EDM02236	(Get FASTA)	NCBI Sequence Viewer

Reference Sequences

RefSeq Acc Id:

NP_001101855 ⟸ NM_001108385

- Sequence:

show sequence

MERLQKQPLTSPGSVSSSRDSSVPGSPSNIVAKMDNQVLGYKDLAAIPKDKAILDIERPDLMIY
EPHFTYSLLEHVELPRSRECSLSPKSTSPPPSPEVWAESRTLGIISQASTPRTTGTPRTSLPHF
HHPETTRPDSNIYKKPPIYKQRESVGGSPQSKHLIEDLIIESSKFPAAQPPDPNQPAKIETDYW
PCPPSLAVVETEWRKRKASRKGAEEEEEEEDDDSEEEIKAIRERQKEELSKVTSNLGKMILKEE
MEKSLPIRRKTRSLPDRTPFHTSLHSGTSKSSSLPSYGRTTLSRLQSTEFSPSGSEAGSPDLSL

hide sequence

RefSeq Acc Id:

XP_006252343 ⟸ XM_006252281

- Peptide Label:

isoform X3

- Sequence:

show sequence

MERLQKAKMDNQVLGYKDLAAIPKDKAILDIERPDLMIYEPHFTYSLLEHVELPRSRECSLSPK
STSPPPSPEVWAESRTLGIISQASTPRTTGTPRTSLPHFHHPETTRPDSNIYKKPPIYKQRESV
GGSPQSKHLIEDLIIESSKFPAAQPPDPNQPAKIETDYWPCPPSLAVVETEWRKRKASRKGAEE
EEEEEDDDSEEEIKAIRERQKEELSKVTSNLGKMILKEEMEKSLPIRRKTRSLPDRTPFHTSLH
SGTSKSSSLPSYGRTTLSRLQSTEFSPSGSEAGSPGLQNGEGQRGRMDRGNSLPCVLEQKIYPY
EMLVVTNKGRTKLPPGVDRMRLERHLSAEDFSRVFAMSPEEFGKLALWKRNELKKKASLF

hide sequence

RefSeq Acc Id:

XP_017455236 ⟸ XM_017599747

- Peptide Label:

isoform X2

- Sequence:

show sequence

MERLQKQPLTSPGSVSSSRDSSVPGSPSNIVAKMDNQVLGYKDLAAIPKDKAILDIERPDLMIY
EPHFTYSLLEHVELPRSRECSLSPKSTSPPPSPEVWAESRTLGIISQASTPRTTGTPRTSLPHF
HHPETTRPDSNIYKKPPIYKQRESVGGSPQSKHLIEDLIIESSKFPAAQPPDPNQPAKIETDYW
PCPPSLAVVETEWRKRKASRKGAEEEEEEEDDDSEEEIKAIRERQKEELSKVTSNLGKMILKEE
MEKSLPIRRKTRSLPDRTPFHTSLHSGTSKSSSLPSYGRTTLSRLQSTEFSPSGSEAGSPGLQI
YPYEMLVVTNKGRTKLPPGVDRMRLERHLSAEDFSRVFAMSPEEFGKLALWKRNELKKKASLF

hide sequence

RefSeq Acc Id:

XP_017455235 ⟸ XM_017599746

- Peptide Label:

isoform X1

- Sequence:

show sequence

MERLQKQPLTSPGSVSSSRDSSVPGSPSNIVAKMDNQVLGYKDLAAIPKDKAILDIERPDLMIY
EPHFTYSLLEHVELPRSRECSLSPKSTSPPPSPEVWAESRTLGIISQASTPRTTGTPRTSLPHF
HHPETTRPDSNIYKKPPIYKQRESVGGSPQSKHLIEDLIIESSKFPAAQPPDPNQPAKIETDYW
PCPPSLAVVETEWRKRKASRKGAEEEEEEEDDDSEEEIKAIRERQKEELSKVTSNLGKMILKEE
MEKSLPIRRKTRSLPDRTPFHTSLHSGTSKSSSLPSYGRTTLSRLQSTEFSPSGSEAGSPGLQN
GEGQRGRMDRGNSLPCVLEQKIYPYEMLVVTNKGRTKLPPGVDRMRLERHLSAEDFSRVFAMSP
EEFGKLALWKRNELKKKASLF

hide sequence

RefSeq Acc Id:

ENSRNOP00000059386 ⟸ ENSRNOT00000067776

RefSeq Acc Id:

ENSRNOP00000016555 ⟸ ENSRNOT00000016555

RefSeq Acc Id:

ENSRNOP00000084709 ⟸ ENSRNOT00000097002

RefSeq Acc Id:

ENSRNOP00000097697 ⟸ ENSRNOT00000106565

RefSeq Acc Id:

ENSRNOP00000093095 ⟸ ENSRNOT00000113196

Protein Domains

HP Putative adherens-junction anchoring

Protein Structures

Name	Modeler	Protein Id	AA Range	Protein Structure
AF-B2GUY4-F1-model_v2	AlphaFold	B2GUY4	1-354	view protein structure

Transcriptome

eQTL		View at Phenogen
WGCNA		View at Phenogen
Tissue/Strain Expression		View at Phenogen

Promoters

RGD ID:

13699817

Promoter ID:

EPDNEW_R10340

Type:

single initiation site

Name:

Dmtn_1

Description:

dematin actin binding protein

SO ACC ID:

SO:0000170

Source:

EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)

Experiment Methods:

Single-end sequencing.

Position:

Rat Assembly	Chr	Position (strand)	Source
Rnor_6.0	15	52,320,378 - 52,320,438	EPDNEW

Additional Information

External Database Links

Database	Acc Id	Source(s)
AGR Gene	RGD:1311419	AgrOrtholog
BioCyc Gene	G2FUF-13207	BioCyc
Ensembl Genes	ENSRNOG00000012273	Ensembl, ENTREZGENE, UniProtKB/TrEMBL
Ensembl Protein	ENSRNOP00000016555.4	UniProtKB/TrEMBL
	ENSRNOP00000059386.1	UniProtKB/TrEMBL
	ENSRNOP00000084709	ENTREZGENE
	ENSRNOP00000084709.1	UniProtKB/TrEMBL
	ENSRNOP00000093095.1	UniProtKB/TrEMBL
	ENSRNOP00000097697	ENTREZGENE
	ENSRNOP00000097697.1	UniProtKB/TrEMBL
Ensembl Transcript	ENSRNOT00000016555.6	UniProtKB/TrEMBL
	ENSRNOT00000067776.4	UniProtKB/TrEMBL
	ENSRNOT00000097002	ENTREZGENE
	ENSRNOT00000097002.1	UniProtKB/TrEMBL
	ENSRNOT00000106565	ENTREZGENE
	ENSRNOT00000106565.1	UniProtKB/TrEMBL
	ENSRNOT00000113196.1	UniProtKB/TrEMBL
Gene3D-CATH	1.10.950.10	UniProtKB/TrEMBL
IMAGE_CLONE	IMAGE:8374835	IMAGE-MGC_LOAD
InterPro	AbLIM_anchor	UniProtKB/TrEMBL
	Villin_headpiece	UniProtKB/TrEMBL
	Villin_headpiece_dom_sf	UniProtKB/TrEMBL
KEGG Report	rno:361069	UniProtKB/TrEMBL
MGC_CLONE	MGC:187700	IMAGE-MGC_LOAD
NCBI Gene	361069	ENTREZGENE
PANTHER	ACTIN-BINDING LIM PROTEIN	UniProtKB/TrEMBL
	DEMATIN	UniProtKB/TrEMBL
Pfam	AbLIM_anchor	UniProtKB/TrEMBL
	VHP	UniProtKB/TrEMBL
PhenoGen	Dmtn	PhenoGen
PROSITE	PS51089	UniProtKB/TrEMBL
SMART	VHP	UniProtKB/TrEMBL
Superfamily-SCOP	SSF47050	UniProtKB/TrEMBL
UniProt	A0A8I5ZXT2	ENTREZGENE, UniProtKB/TrEMBL
	A0A8I6AIW7_RAT	UniProtKB/TrEMBL
	A0A8I6AT61_RAT	UniProtKB/TrEMBL
	B2GUY4_RAT	UniProtKB/TrEMBL
	D4A559_RAT	UniProtKB/TrEMBL
UniProt Secondary	E9PT80	UniProtKB/TrEMBL

Nomenclature History

Date	Current Symbol	Current Name	Previous Symbol	Previous Name	Description	Reference	Status
2013-06-05	Dmtn	dematin actin binding protein	Epb49	erythrocyte membrane protein band 4.9 (dematin)	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2011-01-24	Epb49	erythrocyte membrane protein band 4.9 (dematin)	Epb49	erythrocyte membrane protein band 4.9	Nomenclature updated to reflect human and mouse nomenclature	1299863	APPROVED
2008-04-30	Epb4.9	erythrocyte protein band 4.9	Epb4.9_predicted	erythrocyte protein band 4.9 (predicted)	'predicted' is removed	2292626	APPROVED
2005-01-12	Epb4.9_predicted	erythrocyte protein band 4.9 (predicted)			Symbol and Name status set to approved	70820	APPROVED

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar