Ak8 (adenylate kinase 8) - Rat Genome Database

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Gene: Ak8 (adenylate kinase 8) Rattus norvegicus
Analyze
Symbol: Ak8
Name: adenylate kinase 8
RGD ID: 1303144
Description: Predicted to enable AMP binding activity and nucleobase-containing compound kinase activity. Predicted to be involved in nucleoside monophosphate phosphorylation. Predicted to act upstream of or within ventricular system development. Predicted to be located in axoneme and sperm flagellum. Predicted to be active in cytoplasm. Orthologous to human AK8 (adenylate kinase 8); INTERACTS WITH 6-propyl-2-thiouracil; bisphenol A; cadmium dichloride.
Type: protein-coding
RefSeq Status: PROVISIONAL
Previously known as: AK 8; ATP-AMP transphosphorylase 8; HypB, AroK, ADK and rho factor domain containing protein RGD1303144; MGC94995; putative adenylate kinase-like protein C9orf98 homolog; RGD1303144; similar to hypothetical protein FLJ32704
RGD Orthologs
Human
Mouse
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Latest Assembly: GRCr8 - GRCr8 Assembly
Position:
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8332,426,892 - 32,542,432 (+)NCBIGRCr8
mRatBN7.2312,028,895 - 12,144,468 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl312,028,954 - 12,144,465 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx315,101,345 - 15,217,466 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0323,686,303 - 23,802,434 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0321,940,760 - 22,056,878 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.037,279,429 - 7,394,509 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl37,279,340 - 7,394,513 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0312,630,063 - 12,742,336 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.437,687,426 - 7,821,194 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.137,687,725 - 7,821,493 (+)NCBI
Celera36,809,674 - 6,924,371 (+)NCBICelera
Cytogenetic Map3p12NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Ak8Ratdevelopmental and epileptic encephalopathy  ISOAK8 (Homo sapiens)8554872ClinVar Annotator: match by term: Developmental and epileptic encephalopathyClinVarPMID:28492532
Ak8Ratdevelopmental and epileptic encephalopathy 14  ISOAK8 (Homo sapiens)8554872ClinVar Annotator: match by term: Developmental and epileptic encephalopathy and 14ClinVarPMID:28492532
Ak8Ratearly infantile epileptic encephalopathy  ISOAK8 (Homo sapiens)8554872ClinVar Annotator: match by term: Early infantile epileptic encephalopathyClinVarPMID:28492532
Ak8RatEhlers-Danlos syndrome classic type 1  ISOAK8 (Homo sapiens)8554872ClinVar Annotator: match by term: Ehlers-Danlos syndrome and classic typeClinVarPMID:28492532
Ak8RatLeigh disease  ISOAK8 (Homo sapiens)8554872ClinVar Annotator: match by term: Leigh syndromeClinVarPMID:28492532
Ak8Ratprimary coenzyme Q10 deficiency 7  ISOAK8 (Homo sapiens)8554872ClinVar Annotator: match by term: Neonatal encephalomyopathy-cardiomyopathy-respiratory distress syndromeClinVarPMID:28492532
Ak8RatRafiq syndrome  ISOAK8 (Homo sapiens)8554872ClinVar Annotator: match by term: Rafiq syndromeClinVarPMID:28492532
Ak8Rattuberous sclerosis 1  ISOAK8 (Homo sapiens)8554872ClinVar Annotator: match by term: Tuberous sclerosis 1ClinVarPMID:25741868 and PMID:28492532
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Ak8Rathydrocephalus  ISSAk8 (Mus musculus)13592920OMIM:123155 more ...MouseDO 

1 to 20 of 41 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Ak8Rat4,4'-sulfonyldiphenol increases expressionISOAk8 (Mus musculus)6480464bisphenol S results in increased expression of AK8 mRNACTDPMID:30951980
Ak8Rat6-propyl-2-thiouracil affects expressionEXP 6480464Propylthiouracil affects the expression of AK8 mRNACTDPMID:24780913
Ak8Rat6-propyl-2-thiouracil decreases expressionEXP 6480464Propylthiouracil results in decreased expression of AK8 mRNACTDPMID:25825206 and PMID:30047161
Ak8Ratacrylamide increases expressionISOAk8 (Mus musculus)6480464Acrylamide results in increased expression of AK8 mRNACTDPMID:30807115
Ak8Rataflatoxin B1 decreases expressionISOAK8 (Homo sapiens)6480464Aflatoxin B1 results in decreased expression of AK8 mRNACTDPMID:32234424
Ak8Rataldehydo-D-glucose increases expressionISOAk8 (Mus musculus)6480464Glucose results in increased expression of AK8 mRNACTDPMID:33448797
Ak8Rataldehydo-D-glucose multiple interactionsISOAk8 (Mus musculus)6480464fucoxanthin inhibits the reaction [Glucose results in increased expression of AK8 mRNA]CTDPMID:33448797
Ak8Ratbenzo[a]pyrene decreases expressionISOAk8 (Mus musculus)6480464Benzo(a)pyrene results in decreased expression of AK8 mRNACTDPMID:22228805
Ak8Ratbenzo[a]pyrene decreases expressionISOAK8 (Homo sapiens)6480464Benzo(a)pyrene results in decreased expression of AK8 mRNACTDPMID:32234424
Ak8Ratbenzo[a]pyrene affects methylationISOAK8 (Homo sapiens)6480464Benzo(a)pyrene affects the methylation of AK8 intronCTDPMID:30157460
Ak8Ratbisphenol A decreases expressionEXP 6480464bisphenol A results in decreased expression of AK8 mRNACTDPMID:25181051
Ak8Ratbisphenol A decreases methylationISOAK8 (Homo sapiens)6480464bisphenol A results in decreased methylation of AK8 geneCTDPMID:31601247
Ak8Ratbisphenol A increases methylationEXP 6480464bisphenol A results in increased methylation of AK8 geneCTDPMID:28505145
Ak8Ratbisphenol A increases expressionEXP 6480464bisphenol A results in increased expression of AK8 mRNACTDPMID:30816183 and PMID:32528016
Ak8Ratbisphenol F increases expressionISOAk8 (Mus musculus)6480464bisphenol F results in increased expression of AK8 mRNACTDPMID:30951980
Ak8Ratcadmium dichloride increases methylationEXP 6480464Cadmium Chloride results in increased methylation of AK8 promoterCTDPMID:22457795
Ak8Ratcarbon nanotube decreases expressionISOAk8 (Mus musculus)6480464Nanotubes more ...CTDPMID:25554681
Ak8Ratchloroprene increases expressionISOAk8 (Mus musculus)6480464Chloroprene results in increased expression of AK8 mRNACTDPMID:23125180
Ak8Ratchlorpyrifos increases expressionISOAk8 (Mus musculus)6480464Chlorpyrifos results in increased expression of AK8 mRNACTDPMID:37019170
Ak8Ratcisplatin decreases expressionISOAK8 (Homo sapiens)6480464Cisplatin results in decreased expression of AK8 mRNACTDPMID:27392435

1 to 20 of 41 rows

Biological Process

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Ak8Ratnucleobase-containing compound metabolic process involved_inIEAInterPro:IPR0008501600115GO_REF:0000002InterProGO_REF:0000002
Ak8Ratnucleoside monophosphate phosphorylation involved_inIEAGO:00040171600115GO_REF:0000108GOCGO_REF:0000108
Ak8Ratventricular system development acts_upstream_of_or_withinISOAk8 (Mus musculus)1624291MGI:5429197 PMID:21746835RGDPMID:21746835
Ak8Ratventricular system development acts_upstream_of_or_withinIEAUniProtKB:Q32M07 and ensembl:ENSMUSP000000737891600115GO_REF:0000107EnsemblGO_REF:0000107

Cellular Component
1 to 13 of 13 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Ak8Rat9+2 motile cilium located_inISOAK8 (Homo sapiens)1624291 PMID:33139725RGDPMID:33139725
Ak8Rat9+2 motile cilium located_inIEAUniProtKB:Q96MA6 and ensembl:ENSP000002985451600115GO_REF:0000107EnsemblGO_REF:0000107
Ak8Rat9+2 motile cilium located_inISOAK8 (Sus scrofa)1624291 PMID:33139725RGDPMID:33139725
Ak8Rataxoneme located_inISOAK8 (Sus scrofa)1624291 PMID:33139725RGDPMID:33139725
Ak8Rataxoneme located_inIEAUniProtKB:Q32M07 and ensembl:ENSMUSP000000737891600115GO_REF:0000107EnsemblGO_REF:0000107
Ak8Rataxoneme located_inISOAk8 (Mus musculus)1624291 PMID:24740601RGDPMID:24740601
Ak8Ratcell projection located_inIEAUniProtKB-KW:KW-09661600115GO_REF:0000043UniProtGO_REF:0000043
Ak8Ratcytoplasm is_active_inIBAFB:FBgn0028833 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Ak8Ratcytoplasm located_inIEAUniProtKB-KW:KW-09631600115GO_REF:0000043UniProtGO_REF:0000043
Ak8Ratcytoskeleton located_inIEAUniProtKB-KW:KW-02061600115GO_REF:0000043UniProtGO_REF:0000043
Ak8Ratcytosol located_inIEAUniProtKB-SubCell:SL-00911600115GO_REF:0000044UniProtGO_REF:0000044
Ak8Ratsperm flagellum located_inIEAUniProtKB:Q32M07 and ensembl:ENSMUSP000000737891600115GO_REF:0000107EnsemblGO_REF:0000107
Ak8Ratsperm flagellum located_inISOAk8 (Mus musculus)1624291 PMID:24740601RGDPMID:24740601
1 to 13 of 13 rows

Molecular Function
1 to 20 of 24 rows

  
Object Symbol
Species
Term
Qualifier
Evidence
With
Reference
Notes
Source
Original Reference(s)
Ak8Rat(d)CMP kinase activity enablesISOAK8 (Homo sapiens)1624291 PMID:21080915RGDPMID:21080915
Ak8Rat(d)CMP kinase activity enablesIEAUniProtKB:Q96MA6 and ensembl:ENSP000002985451600115GO_REF:0000107EnsemblGO_REF:0000107
Ak8Rat(d)CMP kinase activity enablesISSUniProtKB:Q96MA61600115GO_REF:0000024UniProtGO_REF:0000024
Ak8Ratadenylate kinase activity enablesIEAInterPro:IPR0361931600115GO_REF:0000002InterProGO_REF:0000002
Ak8Ratadenylate kinase activity enablesIEARHEA:129731600115GO_REF:0000116RHEAGO_REF:0000116
Ak8Ratadenylate kinase activity enablesIEAEC:2.7.4.31600115GO_REF:0000003UniProtGO_REF:0000003
Ak8Ratadenylate kinase activity enablesIBAFB:FBgn0022709 more ...1600115GO_REF:0000033GO_CentralGO_REF:0000033
Ak8Ratadenylate kinase activity enablesIEAUniProtKB:Q96MA6 and ensembl:ENSP000002985451600115GO_REF:0000107EnsemblGO_REF:0000107
Ak8Ratadenylate kinase activity enablesISSUniProtKB:Q96MA61600115GO_REF:0000024UniProtGO_REF:0000024
Ak8Ratadenylate kinase activity enablesISOAK8 (Homo sapiens)1624291 PMID:21080915RGDPMID:21080915
Ak8RatAMP binding enablesISOAK8 (Homo sapiens)1624291 PMID:33139725RGDPMID:33139725
Ak8RatAMP binding enablesIEAUniProtKB:Q96MA6 and ensembl:ENSP000002985451600115GO_REF:0000107EnsemblGO_REF:0000107
Ak8RatATP binding enablesIEAUniProtKB-KW:KW-00671600115GO_REF:0000043UniProtGO_REF:0000043
Ak8RatATP binding enablesIEAInterPro:IPR0008501600115GO_REF:0000002InterProGO_REF:0000002
Ak8Ratkinase activity enablesIEAUniProtKB-KW:KW-04181600115GO_REF:0000043UniProtGO_REF:0000043
Ak8Ratnucleobase-containing compound kinase activity enablesIEAInterPro:IPR0008501600115GO_REF:0000002InterProGO_REF:0000002
Ak8Ratnucleoside diphosphate kinase activity enablesISSUniProtKB:Q96MA61600115GO_REF:0000024UniProtGO_REF:0000024
Ak8Ratnucleoside diphosphate kinase activity enablesIEAEC:2.7.4.61600115GO_REF:0000003UniProtGO_REF:0000003
Ak8Ratnucleoside diphosphate kinase activity enablesIEAUniProtKB:Q96MA6 and ensembl:ENSP000002985451600115GO_REF:0000107EnsemblGO_REF:0000107
Ak8Ratnucleoside diphosphate kinase activity enablesISOAK8 (Homo sapiens)1624291 PMID:23416111RGDPMID:23416111
1 to 20 of 24 rows


#
Reference Title
Reference Citation
1. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, etal., Brief Bioinform. 2011 Sep;12(5):449-62. doi: 10.1093/bib/bbr042. Epub 2011 Aug 27.
2. Rat ISS GO annotations from MGI mouse gene data--August 2006 MGD data from the GO Consortium
3. GOA pipeline RGD automated data pipeline
4. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
5. Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences. Strausberg RL, etal., Proc Natl Acad Sci U S A. 2002 Dec 24;99(26):16899-903. Epub 2002 Dec 11.
PMID:10215863   PMID:21080915   PMID:21746835   PMID:23416111   PMID:24740601  



Ak8
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8332,426,892 - 32,542,432 (+)NCBIGRCr8
mRatBN7.2312,028,895 - 12,144,468 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl312,028,954 - 12,144,465 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx315,101,345 - 15,217,466 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0323,686,303 - 23,802,434 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0321,940,760 - 22,056,878 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.037,279,429 - 7,394,509 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl37,279,340 - 7,394,513 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0312,630,063 - 12,742,336 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.437,687,426 - 7,821,194 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.137,687,725 - 7,821,493 (+)NCBI
Celera36,809,674 - 6,924,371 (+)NCBICelera
Cytogenetic Map3p12NCBI
AK8
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh389132,725,578 - 132,879,046 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl9132,725,578 - 132,878,777 (-)EnsemblGRCh38hg38GRCh38
GRCh379135,600,965 - 135,754,433 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 369134,590,786 - 134,744,019 (-)NCBINCBI36Build 36hg18NCBI36
Build 349132,630,518 - 132,783,752NCBI
Celera9106,142,640 - 106,295,933 (-)NCBICelera
Cytogenetic Map9q34.13NCBI
HuRef9105,094,698 - 105,248,118 (-)NCBIHuRef
CHM1_19135,751,293 - 135,904,675 (-)NCBICHM1_1
T2T-CHM13v2.09144,936,841 - 145,090,859 (-)NCBIT2T-CHM13v2.0
Ak8
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39228,588,287 - 28,703,177 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl228,590,176 - 28,703,177 (+)EnsemblGRCm39 Ensembl
GRCm38228,698,275 - 28,813,165 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl228,700,164 - 28,813,165 (+)EnsemblGRCm38mm10GRCm38
MGSCv37228,555,681 - 28,668,685 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36228,522,173 - 28,635,167 (+)NCBIMGSCv36mm8
Celera228,404,667 - 28,518,225 (+)NCBICelera
Cytogenetic Map2A3NCBI
cM Map219.38NCBI
Ak8
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555132,065,004 - 2,185,404 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555132,069,187 - 2,185,469 (-)NCBIChiLan1.0ChiLan1.0
AK8
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2116,481,022 - 6,633,766 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan196,483,355 - 6,636,112 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v09103,842,850 - 103,995,331 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.19132,473,492 - 132,625,313 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl9132,473,495 - 132,625,313 (-)Ensemblpanpan1.1panPan2
AK8
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1951,470,688 - 51,598,787 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl951,470,756 - 51,598,786 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha950,735,701 - 50,863,518 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0952,365,877 - 52,493,657 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl952,365,861 - 52,493,656 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1951,144,257 - 51,271,985 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0951,468,738 - 51,596,498 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0951,548,262 - 51,676,101 (+)NCBIUU_Cfam_GSD_1.0
Ak8
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947199,443,628 - 199,553,090 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648719,209,958 - 19,319,932 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648719,212,155 - 19,321,601 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
AK8
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1272,497,662 - 272,625,660 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11272,497,661 - 272,625,668 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21306,529,989 - 306,557,132 (-)NCBISscrofa10.2Sscrofa10.2susScr3
AK8
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1125,263,126 - 5,414,543 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl125,263,266 - 5,414,927 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607910,226,386 - 10,383,078 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Ak8
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247603,545,403 - 3,660,658 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247603,545,491 - 3,666,266 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2

.

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Variants in Ak8
580 total Variants

Predicted Target Of
Summary Value
Count of predictions:60
Count of miRNA genes:55
Interacting mature miRNAs:58
Transcripts:ENSRNOT00000017029
Prediction methods:Microtar, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


1 to 10 of 22 rows
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD ID
Symbol
Name
LOD
P Value
Trait
Sub Trait
Chr
Start
Stop
Species
1558647Cm46Cardiac mass QTL 465.40.0000055heart mass (VT:0007028)heart wet weight (CMO:0000069)31077882330356773Rat
1358357Srcrtb1Stress Responsive Cort Basal QTL 16.360.002blood corticosterone amount (VT:0005345)plasma corticosterone level (CMO:0001173)3865816227494778Rat
6893355Bw101Body weight QTL 1010.40.38body mass (VT:0001259)body weight (CMO:0000012)31077870430357018Rat
4889966Bss95Bone structure and strength QTL 954.4tibia area (VT:1000281)tibia-fibula cross-sectional area (CMO:0001718)3136847613Rat
1558654Bw56Body weight QTL 564.50.0000171body mass (VT:0001259)body weight (CMO:0000012)31077870430357018Rat
10401810Kidm53Kidney mass QTL 53kidney mass (VT:0002707)both kidneys wet weight to body weight ratio (CMO:0000340)3822719447233430Rat
1298526Arunc3Aerobic running capacity QTL 32.2exercise endurance trait (VT:0002332)maximum distance run on treadmill (CMO:0001406)3822719433703538Rat
8693641Alc30Alcohol consumption QTL 3020.739drinking behavior trait (VT:0001422)calculated ethanol drink intake rate (CMO:0001615)31043430624512004Rat
1558650Cm48Cardiac mass QTL 4840.0001heart mass (VT:0007028)heart weight to body weight ratio (CMO:0000074)31077882330356773Rat
1358905Hrtrt17Heart rate QTL 175.90.000014heart pumping trait (VT:2000009)heart rate (CMO:0000002)31086191289878372Rat

1 to 10 of 22 rows
BE118976  
Rat AssemblyChrPosition (strand)SourceJBrowse
mRatBN7.2312,144,263 - 12,144,462 (+)MAPPERmRatBN7.2
Rnor_6.037,394,305 - 7,394,503NCBIRnor6.0
Rnor_5.0312,742,132 - 12,742,330UniSTSRnor5.0
RGSC_v3.437,820,990 - 7,821,188UniSTSRGSC3.4
Celera36,924,167 - 6,924,365UniSTS
RH 3.4 Map326.7UniSTS
Cytogenetic Map3p12UniSTS




alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
nervous system
renal system
reproductive system
respiratory system
7 4 17 112 63 62 31 25 31 5 135 63 93 32 59 31



Ensembl Acc Id: ENSRNOT00000017029   ⟹   ENSRNOP00000017029
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
mRatBN7.2 Ensembl312,028,954 - 12,144,465 (+)Ensembl
Rnor_6.0 Ensembl37,279,340 - 7,394,513 (+)Ensembl
RefSeq Acc Id: NM_001004266   ⟹   NP_001004266
RefSeq Status: PROVISIONAL
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8332,426,928 - 32,542,432 (+)NCBI
mRatBN7.2312,028,954 - 12,144,468 (+)NCBI
Rnor_6.037,279,429 - 7,394,509 (+)NCBI
Rnor_5.0312,630,063 - 12,742,336 (+)NCBI
RGSC_v3.437,687,426 - 7,821,194 (+)RGD
Celera36,809,674 - 6,924,371 (+)RGD
Sequence:
RefSeq Acc Id: XM_006233794   ⟹   XP_006233856
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8332,426,895 - 32,542,432 (+)NCBI
mRatBN7.2312,028,895 - 12,144,468 (+)NCBI
Rnor_6.037,279,442 - 7,394,509 (+)NCBI
Rnor_5.0312,630,063 - 12,742,336 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017591825   ⟹   XP_017447314
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8332,426,901 - 32,542,432 (+)NCBI
mRatBN7.2312,028,895 - 12,144,468 (+)NCBI
Rnor_6.037,279,444 - 7,394,509 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017591826   ⟹   XP_017447315
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8332,426,893 - 32,542,432 (+)NCBI
mRatBN7.2312,028,895 - 12,144,468 (+)NCBI
Rnor_6.037,279,442 - 7,394,509 (+)NCBI
Sequence:
RefSeq Acc Id: XM_017591827   ⟹   XP_017447316
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8332,426,892 - 32,542,432 (+)NCBI
mRatBN7.2312,029,354 - 12,144,468 (+)NCBI
Rnor_6.037,279,438 - 7,394,509 (+)NCBI
Sequence:
RefSeq Acc Id: XM_039105221   ⟹   XP_038961149
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8332,426,895 - 32,534,970 (+)NCBI
mRatBN7.2312,028,895 - 12,114,970 (+)NCBI
RefSeq Acc Id: XM_039105222   ⟹   XP_038961150
Type: CODING
Position:
Rat AssemblyChrPosition (strand)Source
GRCr8332,426,895 - 32,497,182 (+)NCBI
mRatBN7.2312,028,895 - 12,104,046 (+)NCBI
RefSeq Acc Id: NP_001004266   ⟸   NM_001004266
- UniProtKB: Q68FP8 (UniProtKB/Swiss-Prot),   A6JTP9 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_006233856   ⟸   XM_006233794
- Peptide Label: isoform X1
- UniProtKB: A6JTQ0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017447316   ⟸   XM_017591827
- Peptide Label: isoform X1
- UniProtKB: A6JTQ0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017447315   ⟸   XM_017591826
- Peptide Label: isoform X1
- UniProtKB: A6JTQ0 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: XP_017447314   ⟸   XM_017591825
- Peptide Label: isoform X1
- UniProtKB: A6JTQ0 (UniProtKB/TrEMBL)
- Sequence:

Name Modeler Protein Id AA Range Protein Structure
AF-Q68FP8-F1-model_v2 AlphaFold Q68FP8 1-479 view protein structure


eQTL   View at Phenogen
WGCNA   View at Phenogen
Tissue/Strain Expression   View at Phenogen

RGD ID:13691937
Promoter ID:EPDNEW_R2462
Type:multiple initiation site
Name:Ak8_1
Description:adenylate kinase 8
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Rat AssemblyChrPosition (strand)Source
Rnor_6.037,279,418 - 7,279,478EPDNEW


1 to 25 of 25 rows
Database
Acc Id
Source(s)
BioCyc Gene G2FUF-50271 BioCyc
BioCyc Pathway PWY-7219 [adenosine ribonucleotides de novo biosynthesis] BioCyc
BioCyc Pathway Image PWY-7219 BioCyc
Ensembl Genes ENSRNOG00000012761 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENSRNOT00000017029 ENTREZGENE
  ENSRNOT00000017029.6 UniProtKB/Swiss-Prot
  ENSRNOT00000147118 ENTREZGENE
Gene3D-CATH 3.40.50.300 UniProtKB/Swiss-Prot
IMAGE_CLONE IMAGE:7115585 IMAGE-MGC_LOAD
InterPro Adenylat/UMP-CMP_kin UniProtKB/Swiss-Prot
  ADK_active_lid_dom_sf UniProtKB/Swiss-Prot
  P-loop_NTPase UniProtKB/Swiss-Prot
KEGG Report rno:311833 UniProtKB/Swiss-Prot
MGC_CLONE MGC:94995 IMAGE-MGC_LOAD
NCBI Gene 311833 ENTREZGENE
PANTHER PTHR23359 UniProtKB/Swiss-Prot
Pfam ADK UniProtKB/Swiss-Prot
PhenoGen Ak8 PhenoGen
PRINTS ADENYLTKNASE UniProtKB/Swiss-Prot
RatGTEx ENSRNOG00000012761 RatGTEx
Superfamily-SCOP SSF52540 UniProtKB/Swiss-Prot
  SSF57774 UniProtKB/Swiss-Prot
UniProt A6JTP9 ENTREZGENE, UniProtKB/TrEMBL
  A6JTQ0 ENTREZGENE, UniProtKB/TrEMBL
  KAD8_RAT UniProtKB/Swiss-Prot, ENTREZGENE
1 to 25 of 25 rows


Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2011-08-02 Ak8  adenylate kinase 8  RGD1303144  HypB, AroK, ADK and rho factor domain containing protein RGD1303144  Nomenclature updated to reflect human and mouse nomenclature 1299863 APPROVED
2005-11-17 RGD1303144  HypB, AroK, ADK and rho factor domain containing protein RGD1303144  MGC94995  similar to hypothetical protein FLJ32704  Symbol and Name updated 1299863 APPROVED
2005-09-30 MGC94995        Symbol and Name status set to provisional 70820 PROVISIONAL