Ak8 (adenylate kinase 8) - Rat Genome Database

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Gene: Ak8 (adenylate kinase 8) Heterocephalus glaber
Analyze
Symbol: Ak8
Name: adenylate kinase 8
RGD ID: 18901111
Description: ENCODES a protein that exhibits AMP binding (ortholog); INVOLVED IN ventricular system development (ortholog); ASSOCIATED WITH developmental and epileptic encephalopathy 14 (ortholog); Ehlers-Danlos syndrome classic type 1 (ortholog); genetic disease (ortholog); FOUND IN 9+2 motile cilium (ortholog); axoneme (ortholog); sperm flagellum (ortholog)
Type: protein-coding
RefSeq Status: MODEL
RGD Orthologs
Human
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Alliance Genes
More Info more info ...
Latest Assembly: HetGla 1.0 - Naked Mole-Rat female 1.0 Assembly
Position:
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247603,545,403 - 3,660,658 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247603,545,491 - 3,666,266 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Cellular Component

Molecular Function

References
Additional References at PubMed
PMID:22301074   PMID:30032202  


Genomics

Comparative Map Data
Ak8
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_0046247603,545,403 - 3,660,658 (+)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_0046247603,545,491 - 3,666,266 (+)NCBIHetGla_female_1.0HetGla 1.0hetGla2
AK8
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh389132,725,578 - 132,879,046 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl9132,725,578 - 132,878,777 (-)EnsemblGRCh38hg38GRCh38
GRCh379135,600,965 - 135,754,433 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 369134,590,786 - 134,744,019 (-)NCBINCBI36Build 36hg18NCBI36
Build 349132,630,518 - 132,783,752NCBI
Celera9106,142,640 - 106,295,933 (-)NCBICelera
Cytogenetic Map9q34.13NCBI
HuRef9105,094,698 - 105,248,118 (-)NCBIHuRef
CHM1_19135,751,293 - 135,904,675 (-)NCBICHM1_1
T2T-CHM13v2.09144,936,841 - 145,090,859 (-)NCBIT2T-CHM13v2.0
Ak8
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39228,588,287 - 28,703,177 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl228,590,176 - 28,703,177 (+)EnsemblGRCm39 Ensembl
GRCm38228,698,275 - 28,813,165 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl228,700,164 - 28,813,165 (+)EnsemblGRCm38mm10GRCm38
MGSCv37228,555,681 - 28,668,685 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36228,522,173 - 28,635,167 (+)NCBIMGSCv36mm8
Celera228,404,667 - 28,518,225 (+)NCBICelera
Cytogenetic Map2A3NCBI
cM Map219.38NCBI
Ak8
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr8332,426,892 - 32,542,432 (+)NCBIGRCr8
mRatBN7.2312,028,895 - 12,144,468 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl312,028,954 - 12,144,465 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx315,101,345 - 15,217,466 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.0323,686,303 - 23,802,434 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.0321,940,760 - 22,056,878 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.037,279,429 - 7,394,509 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl37,279,340 - 7,394,513 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0312,630,063 - 12,742,336 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.437,687,426 - 7,821,194 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.137,687,725 - 7,821,493 (+)NCBI
Celera36,809,674 - 6,924,371 (+)NCBICelera
Cytogenetic Map3p12NCBI
Ak8
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555132,065,004 - 2,185,404 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555132,069,187 - 2,185,469 (-)NCBIChiLan1.0ChiLan1.0
AK8
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v2116,481,022 - 6,633,766 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan196,483,355 - 6,636,112 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v09103,842,850 - 103,995,331 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.19132,473,492 - 132,625,313 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl9132,473,495 - 132,625,313 (-)Ensemblpanpan1.1panPan2
AK8
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1951,470,688 - 51,598,787 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl951,470,756 - 51,598,786 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha950,735,701 - 50,863,518 (+)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0952,365,877 - 52,493,657 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl952,365,861 - 52,493,656 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1951,144,257 - 51,271,985 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0951,468,738 - 51,596,498 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0951,548,262 - 51,676,101 (+)NCBIUU_Cfam_GSD_1.0
Ak8
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_024404947199,443,628 - 199,553,090 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_00493648719,209,958 - 19,319,932 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_00493648719,212,155 - 19,321,601 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
AK8
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1272,497,662 - 272,625,660 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11272,497,661 - 272,625,668 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21306,529,989 - 306,557,132 (-)NCBISscrofa10.2Sscrofa10.2susScr3
AK8
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1125,263,126 - 5,414,543 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl125,263,266 - 5,414,927 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366607910,226,386 - 10,383,078 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0


Expression


Sequence


Reference Sequences
RefSeq Acc Id: ENSHGLT00000020763   ⟹   ENSHGLP00000020561
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla_female_1.0 EnsemblNW_0046247603,545,403 - 3,660,658 (+)Ensembl
RefSeq Acc Id: XM_004849033   ⟹   XP_004849090
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247603,545,491 - 3,660,757 (+)NCBI
RefSeq Acc Id: XM_013073621   ⟹   XP_012929075
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247603,545,491 - 3,660,756 (+)NCBI
RefSeq Acc Id: XM_021261812   ⟹   XP_021117471
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247603,545,491 - 3,660,756 (+)NCBI
RefSeq Acc Id: XM_021261813   ⟹   XP_021117472
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247603,545,491 - 3,660,756 (+)NCBI
RefSeq Acc Id: XM_021261814   ⟹   XP_021117473
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247603,545,491 - 3,666,266 (+)NCBI
RefSeq Acc Id: XM_021261815   ⟹   XP_021117474
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247603,545,491 - 3,610,268 (+)NCBI
RefSeq Acc Id: XM_021261816   ⟹   XP_021117475
Type: CODING
Position:
Naked Mole-Rat AssemblyChrPosition (strand)Source
HetGla 1.0NW_0046247603,552,580 - 3,660,756 (+)NCBI
Reference Protein Sequences
RefSeq Acc Id: XP_021117473   ⟸   XM_021261814
- Peptide Label: isoform X5
- UniProtKB: G5AT40 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_004849090   ⟸   XM_004849033
- Peptide Label: isoform X1
- UniProtKB: A0A0P6JHN2 (UniProtKB/TrEMBL),   G5AT40 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021117472   ⟸   XM_021261813
- Peptide Label: isoform X3
- UniProtKB: G5AT40 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_012929075   ⟸   XM_013073621
- Peptide Label: isoform X4
- UniProtKB: A0A0P6JHN2 (UniProtKB/TrEMBL),   G5AT40 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021117471   ⟸   XM_021261812
- Peptide Label: isoform X2
- UniProtKB: A0A0P6JHN2 (UniProtKB/TrEMBL),   G5AT40 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021117474   ⟸   XM_021261815
- Peptide Label: isoform X6
- UniProtKB: G5AT40 (UniProtKB/TrEMBL)
RefSeq Acc Id: XP_021117475   ⟸   XM_021261816
- Peptide Label: isoform X7
- UniProtKB: A0A0P6JHN2 (UniProtKB/TrEMBL),   G5AT40 (UniProtKB/TrEMBL)
RefSeq Acc Id: ENSHGLP00000020561   ⟸   ENSHGLT00000020763


Additional Information

Database Acc Id Source(s)
Ensembl Genes ENSHGLG00000014699 Ensembl, ENTREZGENE
Ensembl Transcript ENSHGLT00000020763 ENTREZGENE
Gene3D-CATH 3.40.50.300 UniProtKB/TrEMBL
InterPro Adenylat/UMP-CMP_kin UniProtKB/TrEMBL
  ADK_active_lid_dom_sf UniProtKB/TrEMBL
  P-loop_NTPase UniProtKB/TrEMBL
NCBI Gene Ak8 ENTREZGENE
PANTHER ADENYLATE KINASE 8 UniProtKB/TrEMBL
  PTHR23359 UniProtKB/TrEMBL
Pfam ADK UniProtKB/TrEMBL
PRINTS ADENYLTKNASE UniProtKB/TrEMBL
Superfamily-SCOP SSF52540 UniProtKB/TrEMBL
  SSF57774 UniProtKB/TrEMBL
UniProt A0A0P6JHN2 ENTREZGENE, UniProtKB/TrEMBL
  G5AT40 ENTREZGENE, UniProtKB/TrEMBL