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RGD DISEASE ONTOLOGY - ANNOTATIONS

RGD uses the Human Disease Ontology (DO, https://disease-ontology.org/) for disease curation across species. RGD automatically downloads each new release of the ontology on a monthly basis. Some additional terms which are required for RGD's curation purposes but are not currently covered in the official version of DO have been added. As corresponding terms are added to DO, these custom terms are retired and the DO terms substituted in existing annotations and subsequently used for curation.
Term:hypertension
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Accession:DOID:10763 term browser browse the term
Definition:An artery disease characterized by chronic elevated blood pressure in the arteries. (DO)
Synonyms:exact_synonym: HTN;   high blood pressure;   high blood pressures;   hyperpiesia;   vascular hypertensive disorder
 related_synonym: hypertensive disease;   increased aldosterone to renin ratio
 primary_id: MESH:D006973
 xref: EFO:0000537;   ICD9CM:401-405.99;   NCI:C3117
For additional species annotation, visit the Alliance of Genome Resources.


show annotations for term's descendants           Sort by:
hypertension term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABAT 4-aminobutyrate aminotransferase ISO RGD PMID:1570022 RGD:1598531 NCBI chr16:8,674,617...8,784,570
Ensembl chr16:8,674,596...8,784,575 		JBrowse link
G ABCC1 ATP binding cassette subfamily C member 1 (ABCC1 blood group) EXP CTD Direct Evidence: marker/mechanism CTD PMID:17272743 NCBI chr16:15,949,143...16,143,053
Ensembl chr16:15,949,138...16,143,257 		JBrowse link
G ABCC8 ATP binding cassette subfamily C member 8 IAGP associated with obesity;DNA:polymorphism:exon: RGD PMID:11030411 RGD:737749 NCBI chr11:17,392,498...17,476,845
Ensembl chr11:17,392,498...17,476,894 		JBrowse link
G ABCC9 ATP binding cassette subfamily C member 9 ISO protein:decreased expression:aorta RGD PMID:15964031 PMID:18471810 RGD:1598644, RGD:2301909 NCBI chr12:21,797,389...21,941,426
Ensembl chr12:21,797,389...21,942,543 		JBrowse link
G ABO ABO, alpha 1-3-N-acetylgalactosaminyltransferase and alpha 1-3-galactosyltransferase susceptibility IAGP associated with COVID-19; DNA:polymorphism:cds:allele A (human) RGD PMID:32379894 RGD:35668862 NCBI chr 9:133,250,401...133,275,201
Ensembl chr 9:133,233,278...133,276,024 		JBrowse link
G ACE angiotensin I converting enzyme treatment
susceptibility		 ISO
EXP
IEA
IAGP		 CTD Direct Evidence: marker/mechanism
protein:increased activity:lung (rat)
DNA:polymorphism		 CTD
RGD		 PMID:15773232 PMID:17473847 PMID:20237592 PMID:27847271 PMID:17392119 More... RGD:1601113, RGD:401793709, RGD:40400899, RGD:1581743, RGD:11039415, RGD:8157611, RGD:1331525, RGD:1601114 NCBI chr17:63,477,061...63,498,373
Ensembl chr17:63,477,061...63,498,380 		JBrowse link
G ACE2 angiotensin converting enzyme 2 treatment IAGP
ISO
EXP		 DNA:SNP:intron:8790A>G, associated with Metabolic Syndrome X (MeSH:D024821)
mRNA, protein:decreased expression:kidney (rat)
CTD Direct Evidence: marker/mechanism|therapeutic
mRNA, protein:decreased expression:aorta		 CTD
RGD		 PMID:12075344 PMID:15833808 PMID:17473847 PMID:18391097 PMID:19221212 More... RGD:1642828, RGD:629626, RGD:9685442, RGD:9685435, RGD:9685433 NCBI chr  X:15,518,197...15,607,211
Ensembl chr  X:15,494,566...15,607,236 		JBrowse link
G ACSM3 acyl-CoA synthetase medium chain family member 3 ISO RGD PMID:8507454 PMID:8094726 RGD:634023, RGD:61050 NCBI chr16:20,674,405...20,797,581
Ensembl chr16:20,610,243...20,797,581 		JBrowse link
G ACTC1 actin alpha cardiac muscle 1 ISO RGD PMID:16343576 RGD:1598724 NCBI chr15:34,790,230...34,795,549
Ensembl chr15:34,790,107...34,795,589 		JBrowse link
G ADA adenosine deaminase ISO RGD PMID:9605386 RGD:1624292 NCBI chr20:44,619,522...44,651,699
Ensembl chr20:44,584,896...44,652,252 		JBrowse link
G ADAMTS16 ADAM metallopeptidase with thrombospondin type 1 motif 16 ISO RGD PMID:23185005 RGD:9685162 NCBI chr 5:5,140,330...5,320,304
Ensembl chr 5:5,140,330...5,320,304 		JBrowse link
G ADCY5 adenylate cyclase 5 ISO
EXP		 mRNA:decreased expression:heart left ventricle
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:12717102 PMID:12717102 RGD:13464134 NCBI chr 3:123,282,296...123,449,090
Ensembl chr 3:123,282,296...123,449,090 		JBrowse link
G ADD1 adducin 1 ISO
EXP
IAGP		 CTD Direct Evidence: marker/mechanism
DNA:polymorphism: :p.G460W (human)		 CTD
RGD		 PMID:15773232 PMID:19199261 PMID:15474463 PMID:9149697 RGD:1302895, RGD:1624953 NCBI chr 4:2,843,844...2,930,062
Ensembl chr 4:2,843,844...2,930,076 		JBrowse link
G ADD2 adducin 2 no_association IAGP
IEA		 DNA:polymorphism
DNA:SNP: :rs4852706 (human)		 RGD
GAD		 PMID:16497648 PMID:24652215 PMID:15118671 RGD:1625293, RGD:10047131, RGD:1331525 NCBI chr 2:70,656,784...70,768,200
Ensembl chr 2:70,607,618...70,768,225 		JBrowse link
G ADD3 adducin 3 ISO RGD PMID:12364392 RGD:704369 NCBI chr10:109,996,373...110,135,565
Ensembl chr10:109,996,368...110,135,565 		JBrowse link
G ADIPOQ adiponectin, C1Q and collagen domain containing EXP CTD Direct Evidence: marker/mechanism CTD PMID:12860835 NCBI chr 3:186,842,710...186,858,463
Ensembl chr 3:186,842,704...186,858,463 		JBrowse link
G ADM adrenomedullin IEP
ISO		 protein:increased expression:plasma
mRNA, protein:increased expression:myocardium, aorta		 RGD PMID:16625237 PMID:16450076 RGD:1625298, RGD:1625300 NCBI chr11:10,305,073...10,307,397
Ensembl chr11:10,305,073...10,307,397 		JBrowse link
G ADORA1 adenosine A1 receptor treatment
no_association		 ISO
IAGP		 associated with diabetes mellitus, experimental RGD PMID:8998253 PMID:9597368 PMID:15257174 RGD:1625366, RGD:1625365, RGD:1625367 NCBI chr 1:203,127,726...203,167,405
Ensembl chr 1:203,090,654...203,167,405 		JBrowse link
G ADORA2A adenosine A2a receptor no_association IAGP
IEA		 RGD
GAD		 PMID:15257174 PMID:15118671 RGD:1625367, RGD:1331525 NCBI chr22:24,423,597...24,442,357
Ensembl chr22:24,417,879...24,442,357 		JBrowse link
G ADRA1A adrenoceptor alpha 1A ISO
IDA		 mRNA:decreased expression:aorta RGD PMID:16371063 PMID:19011682 RGD:1625770, RGD:5688340 NCBI chr 8:26,748,150...26,867,379
Ensembl chr 8:26,748,150...26,867,278 		JBrowse link
G ADRA1B adrenoceptor alpha 1B ISO RGD PMID:16095979 RGD:1625771 NCBI chr 5:159,865,086...159,989,205
Ensembl chr 5:159,865,080...159,973,012 		JBrowse link
G ADRA2A adrenoceptor alpha 2A no_association IAGP
EXP
ISO		 DNA:polymorphism
CTD Direct Evidence: marker/mechanism
mRNA:decreased expression:adrenal gland medulla 		CTD
RGD		 PMID:10694191 PMID:16636200 PMID:20691504 RGD:1625183, RGD:6480490 NCBI chr10:111,077,029...111,080,907
Ensembl chr10:111,077,029...111,080,907 		JBrowse link
G ADRA2B adrenoceptor alpha 2B ISO
IAGP		 DNA:polymorphism (human) RGD PMID:17070424 PMID:18953403 RGD:2313548, RGD:2313541 NCBI chr 2:96,112,876...96,116,571
Ensembl chr 2:96,112,876...96,116,571 		JBrowse link
G ADRB1 adrenoceptor beta 1 ISO
EXP
IDA		 protein:increased expression:aorta
CTD Direct Evidence: marker/mechanism
associated with Diabetes Mellitus, Type 2;		 CTD
RGD		 PMID:9260993 PMID:10673262 PMID:19060223 PMID:20398560 RGD:5129127, RGD:7241549 NCBI chr10:114,043,866...114,046,904
Ensembl chr10:114,043,866...114,046,904 		JBrowse link
G ADRB2 adrenoceptor beta 2 susceptibility
no_association		 IAGP
ISO
IEA		 DNA:polymorphisms
associated with Kidney Failure, Chronic; DNA:SNP:cds:p.R16G (human)
DNA:polymorphisms: :pG16R, p.Q27E, p.T164I (human)
DNA:polymorphisms: :46A>G, 79C>G (human)
DNA:polymorphisms: :p.R16G, p.Q27E		 RGD
GAD		 PMID:16685203 PMID:2471888 PMID:20484896 PMID:15118671 PMID:16041242 More... RGD:1601123, RGD:7175287, RGD:7175066, RGD:1331525, RGD:1578728, RGD:4144883, RGD:1601119 NCBI chr 5:148,826,611...148,828,623
Ensembl chr 5:148,826,611...148,828,623 		JBrowse link
G ADRB3 adrenoceptor beta 3 IAGP associated with Diabetes Mellitus, Non-Insulin-Dependent;DNA:polymorphism: :p.W64R (human) RGD PMID:10981554 RGD:2313166 NCBI chr 8:37,962,990...37,966,599
Ensembl chr 8:37,962,990...37,966,599 		JBrowse link
G AGER advanced glycosylation end-product specific receptor ISO
EXP		 protein:increased expression:kidney
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:32147540 PMID:19018797 RGD:2325653 NCBI chr 6:32,180,969...32,184,253
Ensembl chr 6:32,180,968...32,184,322 		JBrowse link
G AGT angiotensinogen treatment
susceptibility
no_association		 ISO
IAGP
EXP
IEA		 ClinVar Annotator: match by term: Hypertension
CTD Direct Evidence: marker/mechanism|therapeutic
DNA:polymorphisms: :p.T174M, p.M235T (human)
DNA:polymorphism: :p.M235T
DNA:polymorphism:promoter:-20C>A (human)
DNA:polymorphisms: :-6G>A, p.M235T, p.T174M
DNA:polymorphism: :p.M268T (human)
protein:increased expression:plasma, urine		 ClinVar
CTD
RGD		 PMID:43064 PMID:1394429 PMID:1432030 PMID:1849535 PMID:1860718 More... RGD:1358275, RGD:329956421, RGD:11039415, RGD:8549470, RGD:8549469, RGD:8549458, RGD:8548902, RGD:1331525, RGD:1300393, RGD:1601130, RGD:1601141, RGD:1601139, RGD:1601143, RGD:5129166, RGD:5129176 NCBI chr 1:230,702,523...230,745,583
Ensembl chr 1:230,690,776...230,745,576 		JBrowse link
G AGTR1 angiotensin II receptor type 1 treatment
no_association
susceptibility		 ISO
EXP
IEA
IAGP		 CTD Direct Evidence: marker/mechanism
mRNA:increased expression:aortic endothelial cell
DNA:polymorphism:3' utr:1166A>C
DNA:polymorphism:3' utr:g.1166A>C
associated with Sleep Apnea Syndromes		 CTD
RGD		 PMID:8952600 PMID:19047579 PMID:23603059 PMID:27292124 PMID:21346625 More... RGD:5129176, RGD:401793709, RGD:8549458, RGD:5147456, RGD:1331525, RGD:1598885, RGD:1601152, RGD:1601148, RGD:5129169 NCBI chr 3:148,697,903...148,743,003
Ensembl chr 3:148,697,784...148,743,008 		JBrowse link
G AGTR2 angiotensin II receptor type 2 ISO
EXP		 associated with Sleep Apnea Syndromes
CTD Direct Evidence: marker/mechanism
mRNA, protein:decreased expression:kidney		 CTD
RGD		 PMID:15710752 PMID:21040717 PMID:11924718 PMID:19680135 RGD:5129169, RGD:6903865, RGD:6903372 NCBI chr  X:116,170,744...116,174,974
Ensembl chr  X:116,170,744...116,174,974 		JBrowse link
G AGTRAP angiotensin II receptor associated protein ISO protein:increased expression:kidney RGD PMID:18725581 RGD:2314351 NCBI chr 1:11,736,136...11,750,769
Ensembl chr 1:11,736,084...11,754,802 		JBrowse link
G AGXT2 alanine--glyoxylate aminotransferase 2 IAGP DNA:SNP, haplotype:exon:multiple (human) RGD PMID:33879046 RGD:329961321 NCBI chr 5:34,998,102...35,047,949
Ensembl chr 5:34,998,101...35,048,135 		JBrowse link
G AHCY adenosylhomocysteinase ISO associated with hyperhomocysteinemia RGD PMID:16815886 RGD:1601153 NCBI chr20:34,231,981...34,311,836
Ensembl chr20:34,280,268...34,311,802 		JBrowse link
G AHR aryl hydrocarbon receptor treatment EXP
ISO		 CTD Direct Evidence: marker/mechanism
associated with chronic intermittent hypoxia		 CTD
RGD		 PMID:21115475 PMID:31489946 PMID:23528973 PMID:32416216 PMID:30127255 RGD:401793758, RGD:401793732, RGD:401793731, RGD:401793709 NCBI chr 7:17,298,652...17,346,147
Ensembl chr 7:16,916,359...17,346,152 		JBrowse link
G AHRR aryl hydrocarbon receptor repressor treatment ISO RGD PMID:30127255 PMID:31489946 RGD:401793709, RGD:401793758 NCBI chr 5:321,714...438,285
Ensembl chr 5:321,714...438,291 		JBrowse link
G AIF1 allograft inflammatory factor 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:32147540 NCBI chr 6:31,615,234...31,617,015
Ensembl chr 6:31,615,217...31,617,021 		JBrowse link
G AKT1 AKT serine/threonine kinase 1 ISO protein:increased serine phosphorylation:kidney RGD PMID:23323219 RGD:10041025 NCBI chr14:104,769,349...104,795,748
Ensembl chr14:104,769,349...104,795,759 		JBrowse link
G AKT2 AKT serine/threonine kinase 2 ISO mRNA:increased expression:cerebral cortex (rat) RGD PMID:12902546 RGD:2313350 NCBI chr19:40,230,317...40,285,345
Ensembl chr19:40,230,317...40,285,536 		JBrowse link
G ALAD aminolevulinate dehydratase no_association IAGP
EXP		 DNA:polymorphism
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:20123609 PMID:11335187 RGD:1601156 NCBI chr 9:113,386,312...113,401,284
Ensembl chr 9:113,386,312...113,401,290 		JBrowse link
G ALB albumin EXP CTD Direct Evidence: therapeutic CTD PMID:2526952 NCBI chr 4:73,404,287...73,421,482
Ensembl chr 4:73,397,114...73,421,482 		JBrowse link
G ALDH2 aldehyde dehydrogenase 2 family member susceptibility
no_association		 IAGP RGD PMID:11510748 PMID:12484509 RGD:1601164, RGD:1601163 NCBI chr12:111,766,933...111,817,532
Ensembl chr12:111,766,887...111,817,532 		JBrowse link
G ALOX12 arachidonate 12-lipoxygenase, 12S type ISO mRNA:decreased expression:medulla oblongata RGD PMID:16445702 RGD:5509789 NCBI chr17:6,996,049...7,010,754
Ensembl chr17:6,996,049...7,010,754 		JBrowse link
G ALOX15 arachidonate 15-lipoxygenase EXP CTD Direct Evidence: marker/mechanism CTD PMID:22467300 NCBI chr17:4,630,919...4,641,678
Ensembl chr17:4,630,919...4,642,294 		JBrowse link
G ALOX5 arachidonate 5-lipoxygenase ISO RGD PMID:16331105 RGD:1626151 NCBI chr10:45,374,216...45,446,117
Ensembl chr10:45,374,176...45,446,119 		JBrowse link
G ANGPT1 angiopoietin 1 IEP
IMP		 protein:increased expression:plasma, platelet RGD PMID:16942942 PMID:18285514 RGD:1626157, RGD:2316068 NCBI chr 8:107,249,482...107,497,918
Ensembl chr 8:107,249,482...107,498,055 		JBrowse link
G ANGPT2 angiopoietin 2 ISO RGD PMID:19070926 RGD:2314171 NCBI chr 8:6,499,632...6,563,245
Ensembl chr 8:6,499,632...6,563,409 		JBrowse link
G ANXA1 annexin A1 ISO
EXP		 protein:altered localization:vascular associated smooth muscle cell
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:22228705 PMID:16109804 RGD:1599668 NCBI chr 9:73,151,865...73,170,393
Ensembl chr 9:73,151,865...73,170,629 		JBrowse link
G AOC1 amine oxidase copper containing 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:6218830 NCBI chr 7:150,852,120...150,861,504
Ensembl chr 7:150,824,627...150,861,504 		JBrowse link
G AOC3 amine oxidase copper containing 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23154672 NCBI chr17:42,851,199...42,858,124
Ensembl chr17:42,851,184...42,858,130 		JBrowse link
G APLN apelin ISO mRNA:decreased expression:aorta, heart RGD PMID:15664402 RGD:1626176 NCBI chr  X:129,645,259...129,654,956
Ensembl chr  X:129,645,259...129,654,956 		JBrowse link
G APOA1 apolipoprotein A1 ISO
EXP		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:18224302 PMID:23401751 RGD:7241867 NCBI chr11:116,835,751...116,837,622
Ensembl chr11:116,835,751...116,837,622 		JBrowse link
G APOB apolipoprotein B IEA GAD PMID:15118671 RGD:1331525 NCBI chr 2:21,001,429...21,044,073
Ensembl chr 2:21,001,429...21,044,073 		JBrowse link
G APOE apolipoprotein E onset IEA
EXP
ISO		 CTD Direct Evidence: marker/mechanism
mRNA:decreased expression:multiple (rat)		 CTD
RGD		 PMID:20720404 PMID:22228705 PMID:15118671 PMID:20585107 RGD:1331525, RGD:6904214 NCBI chr19:44,905,796...44,909,393
Ensembl chr19:44,905,791...44,909,393 		JBrowse link
G APP amyloid beta precursor protein ISO RGD PMID:29713228 RGD:13703136 NCBI chr21:25,880,550...26,171,128
Ensembl chr21:25,880,535...26,171,128 		JBrowse link
G AQP1 aquaporin 1 (Colton blood group) ISO
EXP		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:22228705 PMID:20156423 RGD:5148031 NCBI chr 7:30,911,853...30,925,516
Ensembl chr 7:30,911,853...30,925,517 		JBrowse link
G AQP2 aquaporin 2 ISO protein:increased expression:kidney medulla RGD PMID:16582573 RGD:1601243 NCBI chr12:49,950,737...49,958,878
Ensembl chr12:49,950,737...49,958,878 		JBrowse link
G AQP4 aquaporin 4 ISO RGD PMID:20156423 RGD:5148031 NCBI chr18:26,852,038...26,865,803
Ensembl chr18:26,852,043...26,865,771 		JBrowse link
G AR androgen receptor treatment ISO
EXP		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:10523385 PMID:15746697 PMID:12397037 RGD:1601245, RGD:10043316 NCBI chr  X:67,544,021...67,730,619
Ensembl chr  X:67,544,021...67,730,619 		JBrowse link
G ARG1 arginase 1 ISO mRNA:increased expression:aorta (rat) RGD PMID:18475148 PMID:17223136 RGD:4142834, RGD:1626296 NCBI chr 6:131,573,226...131,584,329
Ensembl chr 6:131,470,832...131,584,332 		JBrowse link
G ARG2 arginase 2 ISO mRNA:increased expression:lung
mRNA:increased expression:aorta (rat)		 RGD PMID:20039818 PMID:17223136 PMID:18475148 RGD:4143278, RGD:1626296, RGD:4142834 NCBI chr14:67,619,920...67,651,708
Ensembl chr14:67,619,920...67,651,708 		JBrowse link
G ARHGDIA Rho GDP dissociation inhibitor alpha ISO mRNA:decreased expression:urinary bladder
protein:decreased expression:cortical collecting duct 		RGD PMID:19689474 PMID:25164814 RGD:9684972, RGD:9684979 NCBI chr17:81,867,721...81,871,337
Ensembl chr17:81,867,719...81,871,378 		JBrowse link
G ARID1B AT-rich interaction domain 1B treatment ISO RGD PMID:17489020 RGD:9587762 NCBI chr 6:156,776,026...157,210,779
Ensembl chr 6:156,776,020...157,210,779 		JBrowse link
G ARNT aryl hydrocarbon receptor nuclear translocator treatment ISO RGD PMID:23528973 PMID:31489946 RGD:401793732, RGD:401793758 NCBI chr 1:150,809,713...150,876,599
Ensembl chr 1:150,809,713...150,876,708 		JBrowse link
G ARRB2 arrestin beta 2 ISO protein:decreased expression:rostral ventrolateral medulla RGD PMID:27861247 RGD:13506896 NCBI chr17:4,710,632...4,721,497
Ensembl chr17:4,710,596...4,721,499 		JBrowse link
G ATF2 activating transcription factor 2 ISO RGD PMID:11358932 RGD:10047414 NCBI chr 2:175,072,259...175,168,203
Ensembl chr 2:175,072,250...175,168,382 		JBrowse link
G ATG7 autophagy related 7 ISO protein:increased expression:skeletal muscle RGD PMID:24119246 RGD:11557985 NCBI chr 3:11,272,397...11,576,353
Ensembl chr 3:11,272,309...11,557,665 		JBrowse link
G ATOX1 antioxidant 1 copper chaperone EXP CTD Direct Evidence: therapeutic CTD PMID:22753205 NCBI chr 5:151,742,822...151,758,631
Ensembl chr 5:151,742,316...151,772,532 		JBrowse link
G ATP1A1 ATPase Na+/K+ transporting subunit alpha 1 ISO
EXP		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:23416519 PMID:8082931 RGD:1579862 NCBI chr 1:116,373,244...116,404,774
Ensembl chr 1:116,372,668...116,410,261 		JBrowse link
G ATP1A2 ATPase Na+/K+ transporting subunit alpha 2 susceptibility IAGP
EXP
ISO		 CTD Direct Evidence: marker/mechanism
protein:decreased expression:adrenal gland cortex zone		 CTD
RGD		 PMID:16166162 PMID:16243970 PMID:11257061 PMID:11768735 PMID:16243970 RGD:1601254, RGD:1601253, RGD:1601251 NCBI chr 1:160,115,759...160,143,591
Ensembl chr 1:160,115,759...160,143,591 		JBrowse link
G ATP2A3 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 3 ISO RGD PMID:11208768 RGD:68726 NCBI chr17:3,923,873...3,964,437
Ensembl chr17:3,923,868...3,964,464 		JBrowse link
G ATP2B1 ATPase plasma membrane Ca2+ transporting 1 ISO
EXP		 mRNA:increased expression:vascular associated smooth muscle cell
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:19430479 PMID:20137670 RGD:2317726 NCBI chr12:89,588,049...89,709,366
Ensembl chr12:89,588,049...89,709,366 		JBrowse link
G ATP2B3 ATPase plasma membrane Ca2+ transporting 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23416519 NCBI chr  X:153,517,642...153,582,929
Ensembl chr  X:153,517,642...153,582,939 		JBrowse link
G ATP5F1A ATP synthase F1 subunit alpha ISO protein:decreased expression:heart left ventricle (rat) RGD PMID:24388463 RGD:7800726 NCBI chr18:46,080,248...46,104,227
Ensembl chr18:46,080,248...46,104,334 		JBrowse link
G ATP6AP2 ATPase H+ transporting accessory protein 2 ISO RGD PMID:21321306 RGD:5132599 NCBI chr  X:40,580,970...40,606,848
Ensembl chr  X:40,579,372...40,606,848 		JBrowse link
G AVP arginine vasopressin ISO
EXP		 protein:increased expression:carotid artery
CTD Direct Evidence: marker/mechanism
protein:increased expression:plasma		 CTD
RGD		 PMID:1663982 PMID:3346065 PMID:4040330 PMID:6367368 PMID:19133994 More... RGD:1601305, RGD:1601243 NCBI chr20:3,082,556...3,084,724
Ensembl chr20:3,082,556...3,084,724 		JBrowse link
G AVPR1A arginine vasopressin receptor 1A IAGP
ISO		 DNA:SNP
mRNA, protein:increased expression:paraventricular hypothalamic nucleus
mRNA, protein:increased expression:kidney, arteriole		 RGD PMID:17653244 PMID:15475662 PMID:15657301 RGD:2300319, RGD:2300330, RGD:2300322 NCBI chr12:63,142,759...63,151,201
Ensembl chr12:63,142,759...63,151,201 		JBrowse link
G AVPR2 arginine vasopressin receptor 2 severity ISO RGD PMID:12072411 RGD:1298694 NCBI chr  X:153,902,625...153,907,166
Ensembl chr  X:153,902,531...153,907,166 		JBrowse link
G B2M beta-2-microglobulin IEP protein:increased expression:serum RGD PMID:15957539 RGD:1601306 NCBI chr15:44,711,517...44,718,145
Ensembl chr15:44,711,358...44,718,851 		JBrowse link
G BAD BCL2 associated agonist of cell death treatment ISO RGD PMID:20065158 RGD:10053702 NCBI chr11:64,269,828...64,284,704
Ensembl chr11:64,269,830...64,284,704 		JBrowse link
G BAX BCL2 associated X, apoptosis regulator treatment ISO RGD PMID:20065158 RGD:10053702 NCBI chr19:48,954,875...48,961,798
Ensembl chr19:48,954,815...48,961,798 		JBrowse link
G BCHE butyrylcholinesterase IEP RGD PMID:12387587 RGD:1601322 NCBI chr 3:165,772,904...165,837,423
Ensembl chr 3:165,772,904...165,837,462 		JBrowse link
G BCL2 BCL2 apoptosis regulator treatment ISO
EXP		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:10075388 PMID:20065158 RGD:10053702 NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128 		JBrowse link
G BDKRB1 bradykinin receptor B1 ISO
IAGP		 DNA:polymorphisms:CDS:in American-Caucasians,T allele of SNP8, C allele of SNP12, T allele of SNP13 RGD PMID:17988733 PMID:12025958 PMID:15643125 RGD:5129214, RGD:704378, RGD:1625732 NCBI chr14:96,256,210...96,264,763
Ensembl chr14:96,256,210...96,268,967 		JBrowse link
G BDKRB2 bradykinin receptor B2 IAGP
EXP
ISO
IEA		 DNA:SNP:promoter:-58T>C (human)
CTD Direct Evidence: marker/mechanism
protein:increased expression:spinal cord
mRNA:increased expression:hypothalamus		 CTD
RGD		 PMID:10614985 PMID:10904024 PMID:11934804 PMID:15118671 PMID:12025958 RGD:4891034, RGD:4890455, RGD:1331525, RGD:704378 NCBI chr14:96,204,839...96,244,164
Ensembl chr14:96,204,679...96,244,166 		JBrowse link
G BECN1 beclin 1 ISO protein:increased expression:brain RGD PMID:23499735 RGD:11561939 NCBI chr17:42,810,132...42,824,282
Ensembl chr17:42,810,134...42,833,350 		JBrowse link
G BMAL2 basic helix-loop-helix ARNT like 2 IAGP DNA:SNPs: :rs6486121, rs3789327, rs969485(human) RGD PMID:17728404 RGD:2314371 NCBI chr12:27,332,836...27,425,286
Ensembl chr12:27,332,836...27,425,289 		JBrowse link
G BMP2 bone morphogenetic protein 2 treatment ISO RGD PMID:33364953 RGD:329956421 NCBI chr20:6,767,686...6,780,246
Ensembl chr20:6,767,686...6,780,246 		JBrowse link
G BRCA1 BRCA1 DNA repair associated treatment IMP RGD PMID:24239235 RGD:8693672 NCBI chr17:43,044,295...43,170,327
Ensembl chr17:43,044,295...43,170,245 		JBrowse link
G BRS3 bombesin receptor subtype 3 ISO RGD PMID:9367152 RGD:734661 NCBI chr  X:136,487,947...136,493,780
Ensembl chr  X:136,487,947...136,493,780 		JBrowse link
G C3 complement C3 ISO RGD PMID:22416803 RGD:11040890 NCBI chr19:6,677,704...6,720,650
Ensembl chr19:6,677,704...6,730,562 		JBrowse link
G CACNA1C calcium voltage-gated channel subunit alpha1 C EXP CTD Direct Evidence: marker/mechanism CTD PMID:22949532 NCBI chr12:1,970,780...2,697,950
Ensembl chr12:1,970,772...2,697,950 		JBrowse link
G CACNA2D1 calcium voltage-gated channel auxiliary subunit alpha2delta 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:22949532 NCBI chr 7:81,946,444...82,443,956
Ensembl chr 7:81,946,444...82,443,956 		JBrowse link
G CACNB2 calcium voltage-gated channel auxiliary subunit beta 2 susceptibility IAGP DNA:SNP: :rs4373814(human) RGD PMID:24338417 RGD:13513987 NCBI chr10:18,140,424...18,543,557
Ensembl chr10:18,140,424...18,543,557 		JBrowse link
G CALCA calcitonin related polypeptide alpha EXP CTD Direct Evidence: therapeutic CTD PMID:1849535 PMID:9887042 NCBI chr11:14,966,668...14,972,351
Ensembl chr11:14,966,622...14,972,354 		JBrowse link
G CAPN6 calpain 6 ISO associated with high salt diet; mRNA:decreased expression:heart (rat) RGD PMID:15665521 RGD:405101696 NCBI chr  X:111,245,099...111,270,483
Ensembl chr  X:111,245,099...111,270,483 		JBrowse link
G CAPN9 calpain 9 ISO associated with high salt diet; mRNA:decreased expression:heart (rat) RGD PMID:15665521 RGD:405101696 NCBI chr 1:230,747,388...230,801,989
Ensembl chr 1:230,747,384...230,802,003 		JBrowse link
G CASP3 caspase 3 treatment ISO RGD PMID:20065158 PMID:27929425 RGD:10053702, RGD:13782308 NCBI chr 4:184,627,696...184,649,447
Ensembl chr 4:184,627,696...184,650,062 		JBrowse link
G CASP8 caspase 8 ISO RGD PMID:27929425 RGD:13782308 NCBI chr 2:201,233,463...201,287,711
Ensembl chr 2:201,233,443...201,361,836 		JBrowse link
G CASP9 caspase 9 ISO RGD PMID:27929425 RGD:13782308 NCBI chr 1:15,491,401...15,524,912
Ensembl chr 1:15,490,832...15,526,534 		JBrowse link
G CAST calpastatin ISO associated with high salt diet; mRNA:increased expression:heart (rat) RGD PMID:15665521 RGD:405101696 NCBI chr 5:95,961,429...96,774,683
Ensembl chr 5:96,247,756...96,779,595
Ensembl chr 5:96,247,756...96,779,595 		JBrowse link
G CAT catalase ISO
EXP		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:11479740 PMID:20667508 PMID:21593737 PMID:22228705 PMID:16716903 RGD:1580833 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060 		JBrowse link
G CAV1 caveolin 1 ISO
EXP		 protein:increased expression:artery smooth muscle, blood vessel endothelial cell
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:1798635 PMID:17986358 RGD:2289116 NCBI chr 7:116,525,009...116,561,185
Ensembl chr 7:116,524,994...116,561,179 		JBrowse link
G CBS cystathionine beta-synthase EXP CTD Direct Evidence: marker/mechanism CTD PMID:18224302 NCBI chr21:43,053,191...43,076,873
Ensembl chr21:43,053,191...43,076,943 		JBrowse link
G CCL2 C-C motif chemokine ligand 2 ameliorates
treatment		 ISO
EXP		 protein:increased expression:urine
associated with Cardiac Fibrosis
CTD Direct Evidence: marker/mechanism
associated with Diabetes Mellitus, Non-Insulin-Dependent;mRNA, protein:increased expression:kidney cortex, urine		 CTD
RGD		 PMID:20667508 PMID:27292124 PMID:17989143 PMID:25715999 PMID:17922026 More... RGD:2307054, RGD:401794570, RGD:8549771, RGD:2307029 NCBI chr17:34,255,285...34,257,203
Ensembl chr17:34,255,274...34,257,208 		JBrowse link
G CCL28 C-C motif chemokine ligand 28 no_association ISO protein:increased expression:kidney (rat)
mRNA, protein:decreased expression:kidney (rat)		 RGD PMID:16840655 PMID:19829664 RGD:2298761, RGD:4892132 NCBI chr 5:43,356,975...43,412,391
Ensembl chr 5:43,376,645...43,412,391 		JBrowse link
G CCL5 C-C motif chemokine ligand 5 IEP associated with Diabetes Mellitus, Non-Insulin-Dependent;protein:increased expression:serum RGD PMID:15668187 RGD:2307105 NCBI chr17:35,871,491...35,880,360
Ensembl chr17:35,871,491...35,880,793 		JBrowse link
G CCN2 cellular communication network factor 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:16685210 NCBI chr 6:131,948,176...131,951,372
Ensembl chr 6:131,948,176...131,951,372 		JBrowse link
G CCNE1 cyclin E1 ISO protein:increased expression:vascular associated smooth muscle cell RGD PMID:12847112 RGD:2289296 NCBI chr19:29,811,991...29,824,312
Ensembl chr19:29,811,991...29,824,312 		JBrowse link
G CCR5 C-C motif chemokine receptor 5 ISO
IAGP		 mRNA:increased expression:aorta (rat)
DNA:frameshift mutation:cds:p.S185_T195del rs333 (human)		 RGD PMID:20044442 PMID:12680626 RGD:4890416, RGD:1581182 NCBI chr 3:46,370,142...46,376,206
Ensembl chr 3:46,370,946...46,376,206 		JBrowse link
G CD14 CD14 molecule IAGP associated with Glomerulonephritis, IGA; DNA:polymorphism: :-159C>T (human) RGD PMID:22072187 RGD:7204129 NCBI chr 5:140,631,732...140,633,701
Ensembl chr 5:140,631,728...140,633,700 		JBrowse link
G CD36 CD36 molecule (CD36 blood group) ISO
EXP		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:18587397 PMID:18587397 RGD:2300254 NCBI chr 7:80,602,207...80,679,274
Ensembl chr 7:80,369,575...80,679,277 		JBrowse link
G CD82 CD82 molecule ISO mRNA:increased expression:thymus RGD PMID:10321446 RGD:2289422 NCBI chr11:44,564,409...44,620,358
Ensembl chr11:44,564,427...44,620,363 		JBrowse link
G CDKN2A cyclin dependent kinase inhibitor 2A IEP protein:increased expression:kidney RGD PMID:18504326 RGD:2316082 NCBI chr 9:21,967,752...21,995,324
Ensembl chr 9:21,967,752...21,995,301 		JBrowse link
G CDO1 cysteine dioxygenase type 1 ISO protein:decreased expression:brain RGD PMID:6726227 RGD:2301363 NCBI chr 5:115,804,733...115,816,659
Ensembl chr 5:115,804,733...115,816,659 		JBrowse link
G CELA2A chymotrypsin like elastase 2A EXP
IAGP		 CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Hypertension		 CTD
ClinVar		 PMID:21602471 PMID:25741868 PMID:31358993 NCBI chr 1:15,456,732...15,472,091
Ensembl chr 1:15,456,728...15,472,091 		JBrowse link
G CETP cholesteryl ester transfer protein EXP CTD Direct Evidence: marker/mechanism CTD PMID:20511482 NCBI chr16:56,961,950...56,983,845
Ensembl chr16:56,961,923...56,983,845 		JBrowse link
G CHGA chromogranin A no_association IAGP
ISO		 protein:creased expression:adrenal gland
mRNA, protein:increased expression:adrenal gland medulla, plasma
DNA:polymorphisms:promoter		 RGD PMID:21061160 PMID:10803489 PMID:10803489 PMID:20113265 PMID:20729505 RGD:6906897, RGD:6907055, RGD:6907055, RGD:6906902, RGD:6906900 NCBI chr14:92,922,664...92,935,285
Ensembl chr14:92,923,150...92,935,285 		JBrowse link
G CHI3L1 chitinase 3 like 1 ISO mRNA:increased expression:brainstem, solitary tract nucleus (rat) RGD PMID:18703386 RGD:4892597 NCBI chr 1:203,178,931...203,186,704
Ensembl chr 1:203,178,931...203,186,704 		JBrowse link
G CHST12 carbohydrate sulfotransferase 12 ISO mRNA:decreased expression:renal cortex and medulla (rat) RGD PMID:25001272 RGD:8693701 NCBI chr 7:2,403,448...2,448,484
Ensembl chr 7:2,403,588...2,448,484 		JBrowse link
G CLCNKA chloride voltage-gated channel Ka EXP CTD Direct Evidence: marker/mechanism CTD PMID:18480177 NCBI chr 1:16,022,036...16,034,050
Ensembl chr 1:16,018,875...16,034,050 		JBrowse link
G CLCNKB chloride voltage-gated channel Kb no_association IAGP DNA:polymorphism:T481S RGD PMID:15148291 PMID:16003175 RGD:1600684, RGD:1600683 NCBI chr 1:16,043,782...16,057,326
Ensembl chr 1:16,040,252...16,057,311 		JBrowse link
G CLDN16 claudin 16 ISO Protein:decreased serine phosphorylation:kidney RGD PMID:16959063 RGD:1599616 NCBI chr 3:190,290,361...190,412,138
Ensembl chr 3:190,322,541...190,412,138 		JBrowse link
G CLOCK clock circadian regulator ISO mRNA:altered expression:gastrocnemius muscle (rat) RGD PMID:22076133 RGD:9686076 NCBI chr 4:55,427,903...55,546,909
Ensembl chr 4:55,427,903...55,546,909 		JBrowse link
G CLU clusterin IAGP DNA:SNP:exon:866C>T (human) RGD PMID:15925890 RGD:1581195 NCBI chr 8:27,596,917...27,614,700
Ensembl chr 8:27,596,917...27,614,700 		JBrowse link
G CMA1 chymase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:14620933 NCBI chr14:24,505,353...24,508,265
Ensembl chr14:24,505,353...24,508,265 		JBrowse link
G CNR1 cannabinoid receptor 1 ISO RGD PMID:19133994 RGD:2314680 NCBI chr 6:88,139,864...88,167,349
Ensembl chr 6:88,139,864...88,166,347 		JBrowse link
G COL1A1 collagen type I alpha 1 chain EXP CTD Direct Evidence: marker/mechanism CTD PMID:11682445 NCBI chr17:50,184,101...50,201,631
Ensembl chr17:50,184,101...50,201,632 		JBrowse link
G COL3A1 collagen type III alpha 1 chain EXP CTD Direct Evidence: marker/mechanism CTD PMID:11682445 NCBI chr 2:188,974,373...189,012,746
Ensembl chr 2:188,974,373...189,012,746 		JBrowse link
G COL4A5 collagen type IV alpha 5 chain IAGP ClinVar Annotator: match by term: Hypertension ClinVar PMID:9848783 PMID:11223851 PMID:12028435 PMID:17396119 PMID:19728970 More... NCBI chr  X:108,439,838...108,697,545
Ensembl chr  X:108,439,838...108,697,545 		JBrowse link
G COL6A3 collagen type VI alpha 3 chain IAGP DNA:SNP:CDS:E1386K (rs146092501) (human) RGD PMID:30226566 RGD:401851058 NCBI chr 2:237,324,018...237,414,164
Ensembl chr 2:237,324,003...237,414,328 		JBrowse link
G COMT catechol-O-methyltransferase susceptibility ISO
IAGP		 protein:increased expression:cerebral cortex
DNA:polymorphism: :-1187G>C, 186C>T 		RGD PMID:14714585 PMID:17510509 PMID:17978496 PMID:17143180 RGD:2289787, RGD:8662344, RGD:2289729, RGD:2289742 NCBI chr22:19,941,772...19,969,975
Ensembl chr22:19,941,371...19,969,975 		JBrowse link
G CORIN corin, serine peptidase IAGP DNA:SNPs:associated with increased risk RGD PMID:17485366 PMID:16216958 RGD:1626338, RGD:1581219 NCBI chr 4:47,594,001...47,838,067
Ensembl chr 4:47,593,999...47,838,106 		JBrowse link
G COX5B cytochrome c oxidase subunit 5B ISO protein:decreased expression:heart left ventricle RGD PMID:16132109 RGD:2301377 NCBI chr 2:97,646,062...97,648,383
Ensembl chr 2:97,646,062...97,648,383 		JBrowse link
G CPS1 carbamoyl-phosphate synthase 1 ISO protein:decreased expression:liver, mitochondrion RGD PMID:19135993 RGD:2303405 NCBI chr 2:210,477,685...210,679,107
Ensembl chr 2:210,477,682...210,679,107 		JBrowse link
G CREB1 cAMP responsive element binding protein 1 treatment ISO RGD PMID:21697807 RGD:10059385 NCBI chr 2:207,529,962...207,605,988
Ensembl chr 2:207,529,737...207,605,988 		JBrowse link
G CRHR1 corticotropin releasing hormone receptor 1 ISO corticotropin releasing hormone-induced RGD PMID:11036160 RGD:1581302 NCBI chr17:45,784,320...45,835,828
Ensembl chr17:45,784,277...45,835,828 		JBrowse link
G CRHR2 corticotropin releasing hormone receptor 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:10742107 NCBI chr 7:30,651,942...30,700,103
Ensembl chr 7:30,651,942...30,700,129 		JBrowse link
G CRP C-reactive protein ISO
EXP
IDA
IEP		 protein:increased expression:plasma
CTD Direct Evidence: marker/mechanism
protein:increased expression:serum:		 CTD
RGD		 PMID:14620923 PMID:16680063 PMID:19770776 PMID:20667508 PMID:19905982 More... RGD:5131461, RGD:9586008, RGD:9491754 NCBI chr 1:159,712,289...159,714,589
Ensembl chr 1:159,712,289...159,714,589 		JBrowse link
G CTF1 cardiotrophin 1 IEP
ISO		 protein:increased expression:plasma
mRNA:increased expression:cardiac ventricle		 RGD PMID:15716706 PMID:8604995 RGD:1626411, RGD:69823 NCBI chr16:30,895,846...30,903,560
Ensembl chr16:30,896,614...30,903,547 		JBrowse link
G CTSC cathepsin C ISO RGD PMID:657443 RGD:1599651 NCBI chr11:88,293,592...88,337,736
Ensembl chr11:88,265,069...88,359,684 		JBrowse link
G CXCL2 C-X-C motif chemokine ligand 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:22352330 NCBI chr 4:74,097,040...74,099,195
Ensembl chr 4:74,097,040...74,099,196 		JBrowse link
G CXCR2 C-X-C motif chemokine receptor 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:27678262 NCBI chr 2:218,125,294...218,137,251
Ensembl chr 2:218,125,289...218,137,251 		JBrowse link
G CYBA cytochrome b-245 alpha chain ISO
EXP
IAGP		 protein:increased expression:kidney cortex
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:16685210 PMID:17324946 PMID:20505675 PMID:32147540 PMID:20018820 More... RGD:2317853, RGD:4775206, RGD:1580276 NCBI chr16:88,643,289...88,651,053
Ensembl chr16:88,643,275...88,651,083 		JBrowse link
G CYBB cytochrome b-245 beta chain ISO
EXP		 Protein:increased expression:brain
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:16685210 PMID:21593737 PMID:27659729 PMID:27847271 PMID:32147540 More... RGD:1599685 NCBI chr  X:37,780,059...37,813,461
Ensembl chr  X:37,780,018...37,813,461 		JBrowse link
G CYP11A1 cytochrome P450 family 11 subfamily A member 1 ISO mRNA:increased expression:hypothalamus RGD PMID:16116051 RGD:1599701 NCBI chr15:74,337,762...74,367,646
Ensembl chr15:74,337,759...74,367,646 		JBrowse link
G CYP11B1 cytochrome P450 family 11 subfamily B member 1 ISO mRNA:decreased expression:hypothalamus, cerebellum, cortex (rat) RGD PMID:19837774 RGD:4891156 NCBI chr 8:142,872,357...142,879,825
Ensembl chr 8:142,872,356...142,879,846 		JBrowse link
G CYP11B2 cytochrome P450 family 11 subfamily B member 2 IAGP
ISO		 DNA:transition:5' utr:-344C>T (human)
ClinVar Annotator: match by term: Aldosterone to renin ratio, increased
mRNA:increased expression:brainstem, hippocampus, cortex (rat)		 ClinVar
RGD		 PMID:12213905 PMID:12788845 PMID:17003099 PMID:10024332 PMID:18495825 More... RGD:4891152, RGD:2307304, RGD:4891156 NCBI chr 8:142,910,559...142,917,843
Ensembl chr 8:142,910,559...142,917,843 		JBrowse link
G CYP19A1 cytochrome P450 family 19 subfamily A member 1 ISO mRNA:decreased expression:ovary (rat) RGD PMID:19228890 RGD:4761326 NCBI chr15:51,208,057...51,338,596
Ensembl chr15:51,208,057...51,338,601 		JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 treatment ISO
EXP		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:20634294 PMID:22995157 PMID:20634294 PMID:31489946 PMID:23528973 More... RGD:7257731, RGD:401793758, RGD:401793732, RGD:401793709 NCBI chr15:74,719,542...74,725,528
Ensembl chr15:74,719,542...74,725,536 		JBrowse link
G CYP1B1 cytochrome P450 family 1 subfamily B member 1 treatment ISO RGD PMID:23528973 RGD:401793732 NCBI chr 2:38,067,509...38,076,151
Ensembl chr 2:38,066,973...38,109,902 		JBrowse link
G CYP2C18 cytochrome P450 family 2 subfamily C member 18 ISO RGD PMID:18829737 RGD:6903915 NCBI chr10:94,683,729...94,736,190
Ensembl chr10:94,683,729...94,736,190 		JBrowse link
G CYP2C9 cytochrome P450 family 2 subfamily C member 9 IAGP
ISO
IDA		 associated with Diabetes Mellitus, Insulin-Dependent; DNA:polymorphism:cds:I359L (human) RGD PMID:17305793 PMID:18829737 PMID:19669737 RGD:2307150, RGD:6903915, RGD:6903909 NCBI chr10:94,938,658...94,990,091
Ensembl chr10:94,938,658...94,990,091 		JBrowse link
G CYP2J2 cytochrome P450 family 2 subfamily J member 2 susceptibility IAGP
IMP		 DNA:SNP RGD PMID:17286575 PMID:20501636 RGD:1625379, RGD:7243136 NCBI chr 1:59,893,308...59,969,212
Ensembl chr 1:59,893,308...59,926,773 		JBrowse link
G CYP2R1 cytochrome P450 family 2 subfamily R member 1 IAGP DNA:SNP:CDS: rs12794714 (human)
DNA:SNP:CDS:rs12794714 (human)
DNA:SNP:CDS:rs10741657|rs12794714 (human)
DNA:SNP:CDS:rs1993116|rs10741657 (human)		 RGD PMID:34906413 PMID:24974252 PMID:28760944 PMID:30192652 RGD:401900724, RGD:401901148, RGD:401901082, RGD:401901076 NCBI chr11:14,877,440...14,892,443
Ensembl chr11:14,877,440...14,892,231 		JBrowse link
G CYP4A11 cytochrome P450 family 4 subfamily A member 11 IAGP RGD PMID:16144986 RGD:1625567 NCBI chr 1:46,929,188...46,941,476
Ensembl chr 1:46,929,177...46,941,484 		JBrowse link
G CYP4A22 cytochrome P450 family 4 subfamily A member 22 ISO mRNA:decreased expression:kidney cortex RGD PMID:16339392 PMID:18952718 RGD:2303381 RGD:2303383 NCBI chr 1:47,137,441...47,149,727
Ensembl chr 1:47,137,435...47,149,727 		JBrowse link
G CYP4F12 cytochrome P450 family 4 subfamily F member 12 ISO mRNA:increased expression:kidney RGD PMID:16182239 RGD:2301709 NCBI chr19:15,673,087...15,697,174
Ensembl chr19:15,673,018...15,697,174 		JBrowse link
G CYP4F2 cytochrome P450 family 4 subfamily F member 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:30932691 NCBI chr19:15,878,023...15,898,074
Ensembl chr19:15,878,023...15,898,077 		JBrowse link
G DARS2 aspartyl-tRNA synthetase 2, mitochondrial IAGP ClinVar Annotator: match by term: Hypertension ClinVar PMID:16199547 PMID:17384640 PMID:19592391 PMID:22843165 PMID:23065766 More... NCBI chr 1:173,824,673...173,858,546
Ensembl chr 1:173,824,653...173,858,808 		JBrowse link
G DBH dopamine beta-hydroxylase resistance ISO
IAGP		 mRNA:increased expression:heart, adrenal gland (rat)
DNA:polymorphism:5' utr:g.-2073C>T rs1989787 (human)		 RGD PMID:20596792 PMID:20814407 RGD:5129234, RGD:5129211 NCBI chr 9:133,636,363...133,659,329
Ensembl chr 9:133,636,363...133,659,329 		JBrowse link
G DDAH1 dimethylarginine dimethylaminohydrolase 1 susceptibility IAGP RGD PMID:16444868 RGD:1625582 NCBI chr 1:85,318,485...85,578,200
Ensembl chr 1:85,318,481...85,578,363 		JBrowse link
G DIO2 iodothyronine deiodinase 2 susceptibility IAGP protein:substitution:Thr92Ala RGD PMID:17224473 RGD:1626437 NCBI chr14:80,197,526...80,231,057
Ensembl chr14:80,197,526...80,387,757 		JBrowse link
G DRD1 dopamine receptor D1 ISO
IAGP		 RGD PMID:8636408 PMID:10948075 RGD:1300303, RGD:1580869 NCBI chr 5:175,440,036...175,444,182
Ensembl chr 5:175,440,036...175,444,182 		JBrowse link
G DRD2 dopamine receptor D2 IAGP
EXP		 DNA:polymorphism
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:11566895 PMID:15939106 PMID:11494094 RGD:1600905, RGD:1580874 NCBI chr11:113,409,605...113,475,398
Ensembl chr11:113,409,605...113,475,691 		JBrowse link
G DRD3 dopamine receptor D3 ISO RGD PMID:9691085 PMID:11675403 RGD:1580882 RGD:734898 NCBI chr 3:114,127,580...114,199,407
Ensembl chr 3:114,127,580...114,199,407 		JBrowse link
G DRD5 dopamine receptor D5 ISO RGD PMID:12486173 RGD:1580887 NCBI chr 4:9,781,634...9,784,009
Ensembl chr 4:9,781,634...9,784,009 		JBrowse link
G DUSP1 dual specificity phosphatase 1 ISO mRNA, protein:increased expression:aorta RGD PMID:9231829 RGD:2298678 NCBI chr 5:172,768,096...172,771,195
Ensembl chr 5:172,768,096...172,771,195 		JBrowse link
G DUSP5 dual specificity phosphatase 5 EXP CTD Direct Evidence: marker/mechanism CTD PMID:25397684 NCBI chr10:110,497,907...110,511,533
Ensembl chr10:110,497,907...110,511,533 		JBrowse link
G DYNLL1 dynein light chain LC8-type 1 treatment ISO RGD PMID:24035314 RGD:13207430 NCBI chr12:120,469,842...120,498,493
Ensembl chr12:120,469,850...120,498,493 		JBrowse link
G ECE1 endothelin converting enzyme 1 IAGP
EXP
ISO		 CTD Direct Evidence: marker/mechanism
mRNA,protein:increased expression,increased activity:kidney medulla		 CTD
RGD		 PMID:12566389 PMID:15126915 PMID:10894793 RGD:1580904, RGD:7244182 NCBI chr 1:21,217,250...21,345,504
Ensembl chr 1:21,217,247...21,345,572 		JBrowse link
G EDN1 endothelin 1 ISO
EXP
IMP
IEP
IAGP		 protein:increased secretion:plasma (rat)
CTD Direct Evidence: marker/mechanism
human gene in a rat model
associated with Diabetic Nephropathies;protein:increased secretion:plasma
DNA:polymorphism:exon:p.K198N (human)		 CTD
RGD		 PMID:7721406 PMID:8152482 PMID:8440307 PMID:10474778 PMID:10669576 More... RGD:4144829, RGD:8661804, RGD:2313283, RGD:1625065 NCBI chr 6:12,230,516...12,297,194
Ensembl chr 6:12,290,361...12,297,194 		JBrowse link
G EDN2 endothelin 2 IEP
IAGP		 mRNA:increased expression:leukocyte RGD PMID:15007037 PMID:10976780 PMID:10489105 RGD:1625402, RGD:1580916, RGD:1580917 NCBI chr 1:41,478,775...41,484,683
Ensembl chr 1:41,478,775...41,484,683 		JBrowse link
G EDN3 endothelin 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:2059916 NCBI chr20:59,300,611...59,325,992
Ensembl chr20:59,300,443...59,325,992 		JBrowse link
G EDNRA endothelin receptor type A ISO
EXP
IAGP		 associated with Uremia
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:12600921 PMID:20144075 PMID:14616768 RGD:4892284, RGD:1580950 NCBI chr 4:147,481,097...147,544,954
Ensembl chr 4:147,480,917...147,544,954 		JBrowse link
G EDNRB endothelin receptor type B ISO associated with Uremia RGD PMID:20144075 PMID:10749572 RGD:4892284, RGD:628518 NCBI chr13:77,895,487...77,975,527
Ensembl chr13:77,895,481...77,975,529 		JBrowse link
G EGFR epidermal growth factor receptor ISO mRNA, protein:increased expression:renal cortex RGD PMID:15827348 RGD:1580953 NCBI chr 7:55,019,017...55,211,628
Ensembl chr 7:55,019,017...55,211,628 		JBrowse link
G EGLN1 egl-9 family hypoxia inducible factor 1 ISO RGD PMID:22686466 RGD:11252087 NCBI chr 1:231,363,756...231,422,287
Ensembl chr 1:231,363,751...231,422,287 		JBrowse link
G EIF4G2 eukaryotic translation initiation factor 4 gamma 2 ISO mRNA:increased expression:heart left ventricle RGD PMID:12708758 RGD:10755511 NCBI chr11:10,797,046...10,808,926
Ensembl chr11:10,797,050...10,808,940 		JBrowse link
G ELN elastin EXP CTD Direct Evidence: marker/mechanism CTD PMID:17039479 NCBI chr 7:74,028,173...74,069,907
Ensembl chr 7:74,027,789...74,069,907 		JBrowse link
G EMILIN1 elastin microfibril interfacer 1 ISO RGD PMID:16530041 RGD:1580958 NCBI chr 2:27,078,615...27,086,403
Ensembl chr 2:27,078,615...27,086,403 		JBrowse link
G ENG endoglin ISO mRNA:decreased expression:kidney (rat) RGD PMID:19829664 RGD:4892132 NCBI chr 9:127,815,016...127,854,658
Ensembl chr 9:127,811,130...127,854,773 		JBrowse link
G ENO1 enolase 1 ISO RGD PMID:16485256 RGD:1598909 NCBI chr 1:8,861,000...8,878,686
Ensembl chr 1:8,861,000...8,879,190 		JBrowse link
G ENO2 enolase 2 severity IEP protein:increased expression:serum RGD PMID:21130083 RGD:5508770 NCBI chr12:6,914,580...6,923,697
Ensembl chr12:6,913,745...6,923,698 		JBrowse link
G ENTPD2 ectonucleoside triphosphate diphosphohydrolase 2 ISO RGD PMID:20655932 RGD:9685529 NCBI chr 9:137,048,107...137,054,061
Ensembl chr 9:137,048,107...137,054,061 		JBrowse link
G EP300 E1A binding protein p300 ISO protein:increased expression:left ventricle (rat) RGD PMID:18292809 RGD:2312265 NCBI chr22:41,092,592...41,180,077
Ensembl chr22:41,092,510...41,180,077 		JBrowse link
G EPHX2 epoxide hydrolase 2 susceptibility ISO
IAGP		 DNA:missense mutation:cds:p.K55R (human) RGD PMID:16157792 PMID:21720266 PMID:19553349 PMID:20065888 RGD:1580985, RGD:5688733, RGD:5688730, RGD:5688727 NCBI chr 8:27,491,143...27,548,626
Ensembl chr 8:27,490,781...27,545,564 		JBrowse link
G EPO erythropoietin EXP CTD Direct Evidence: marker/mechanism CTD PMID:1516988 PMID:10694834 NCBI chr 7:100,720,468...100,723,700
Ensembl chr 7:100,720,468...100,723,700 		JBrowse link
G EPOR erythropoietin receptor susceptibility IEP induced by erythropoietin; RGD PMID:19458615 RGD:11041646 NCBI chr19:11,377,207...11,384,314
Ensembl chr19:11,377,207...11,384,342 		JBrowse link
G ERAP1 endoplasmic reticulum aminopeptidase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:13678427 NCBI chr 5:96,760,813...96,935,854
Ensembl chr 5:96,760,810...96,808,100 		JBrowse link
G ESR2 estrogen receptor 2 ISO
IAGP		 RGD PMID:11799247 PMID:23608653 PMID:15167447 PMID:11185739 RGD:734949, RGD:7364951, RGD:1581017, RGD:1581015 NCBI chr14:64,226,707...64,338,613
Ensembl chr14:64,084,232...64,338,112 		JBrowse link
G F11 coagulation factor XI EXP CTD Direct Evidence: marker/mechanism CTD PMID:6383834 NCBI chr 4:186,266,189...186,289,681
Ensembl chr 4:186,266,189...186,289,681 		JBrowse link
G F11R F11 receptor susceptibility IAGP
ISO		 DNA:SNPs: :rs790056, rs2774276 (human) RGD PMID:18067551 PMID:17420334 RGD:7488938, RGD:7488939 NCBI chr 1:160,995,211...161,021,152
Ensembl chr 1:160,995,211...161,021,175 		JBrowse link
G F12 coagulation factor XII EXP
IAGP		 CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Hypertension		 CTD
ClinVar		 PMID:6383834 PMID:16638441 PMID:25741868 NCBI chr 5:177,402,141...177,409,564
Ensembl chr 5:177,402,133...177,416,583 		JBrowse link
G F2R coagulation factor II thrombin receptor ISO RGD PMID:9168786 RGD:1581034 NCBI chr 5:76,716,126...76,735,770
Ensembl chr 5:76,716,126...76,735,770 		JBrowse link
G F3 coagulation factor III, tissue factor treatment ISO RGD PMID:21423288 RGD:11341709 NCBI chr 1:94,529,173...94,541,759
Ensembl chr 1:94,529,173...94,541,759 		JBrowse link
G F7 coagulation factor VII IEP
ISO
IDA		 protein:increased activity:plasma (human)
protein:increased activity:plasma (rat)		 RGD PMID:8123879 PMID:812575 PMID:10450539 RGD:2312412, RGD:2312323, RGD:2312402 NCBI chr13:113,105,788...113,120,685
Ensembl chr13:113,105,788...113,120,685 		JBrowse link
G FABP1 fatty acid binding protein 1 IEP protein:increased excretion:urine:possibly related to arteriosclerosis (MeSH:D001161) RGD PMID:15830271 RGD:1626441 NCBI chr 2:88,122,982...88,128,062
Ensembl chr 2:88,122,982...88,128,062 		JBrowse link
G FABP3 fatty acid binding protein 3 susceptibility IAGP DNA:SNPs RGD PMID:18437121 RGD:2307331 NCBI chr 1:31,359,588...31,373,076
Ensembl chr 1:31,365,253...31,376,850 		JBrowse link
G FADD Fas associated via death domain treatment ISO RGD PMID:24355328 RGD:11344883 NCBI chr11:70,203,296...70,207,390
Ensembl chr11:70,203,296...70,207,390 		JBrowse link
G FADS1 fatty acid desaturase 1 ISO RGD PMID:12144877 RGD:1625415 NCBI chr11:61,799,627...61,817,003
Ensembl chr11:61,799,627...61,829,318 		JBrowse link
G FAH fumarylacetoacetate hydrolase ISO mRNA:decreased expression:kidney RGD PMID:15731461 RGD:1559295 NCBI chr15:80,152,789...80,186,949
Ensembl chr15:80,152,490...80,186,946 		JBrowse link
G FBN1 fibrillin 1 ISO protein:increased expression:renal glomerulus (rat) RGD PMID:16380460 RGD:7365080 NCBI chr15:48,408,313...48,645,709
Ensembl chr15:48,408,313...48,645,721 		JBrowse link
G FGF2 fibroblast growth factor 2 ISO associated with Aortic Coarctation RGD PMID:17562191 RGD:8655614 NCBI chr 4:122,826,682...122,898,236
Ensembl chr 4:122,826,682...122,898,236 		JBrowse link
G FGF21 fibroblast growth factor 21 EXP CTD Direct Evidence: therapeutic CTD PMID:29706566 NCBI chr19:48,755,524...48,758,330
Ensembl chr19:48,755,524...48,758,333 		JBrowse link
G FMO3 flavin containing dimethylaniline monoxygenase 3 no_association IAGP DNA:polymorphism:CDS:no association with any of the four common genotypes or haplotypes in a Caucasian population
DNA:nonsense mutation:CDS:amino acid E305X, associated with trimethylaminuria, OMIM:602079		 RGD PMID:16324215 PMID:9536088 RGD:1626466, RGD:1626461 NCBI chr 1:171,090,905...171,117,819
Ensembl chr 1:171,090,901...171,117,819 		JBrowse link
G FN1 fibronectin 1 EXP
ISO		 CTD Direct Evidence: marker/mechanism
mRNA:increased expression:kidney (SHRSP/A3N rat)		 CTD
RGD		 PMID:11682445 PMID:17324946 PMID:11907153 PMID:11682445 RGD:28912746, RGD:30296650 NCBI chr 2:215,360,865...215,436,068
Ensembl chr 2:215,360,440...215,436,073 		JBrowse link
G FNDC5 fibronectin type III domain containing 5 EXP CTD Direct Evidence: therapeutic CTD PMID:32165127 NCBI chr 1:32,862,268...32,872,484
Ensembl chr 1:32,862,268...32,872,482 		JBrowse link
G FOS Fos proto-oncogene, AP-1 transcription factor subunit ISO
EXP		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:12044476 PMID:24039778 PMID:16696897 RGD:7242185 NCBI chr14:75,278,828...75,282,230
Ensembl chr14:75,278,826...75,283,190 		JBrowse link
G FOXP3 forkhead box P3 treatment ISO RGD PMID:24420551 RGD:38549366 NCBI chr  X:49,250,438...49,264,710
Ensembl chr  X:49,250,438...49,264,800 		JBrowse link
G FTO FTO alpha-ketoglutarate dependent dioxygenase ISO
IAGP		 associated with Obesity
DNA:SNP:intron:rs9302652 (human)		 RGD PMID:31801409 PMID:20031594 RGD:329812016, RGD:329901765 NCBI chr16:53,703,963...54,121,941
Ensembl chr16:53,701,692...54,158,512 		JBrowse link
G FXYD2 FXYD domain containing ion transport regulator 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:22228705 NCBI chr11:117,820,057...117,828,089
Ensembl chr11:117,800,844...117,828,698 		JBrowse link
G GABBR1 gamma-aminobutyric acid type B receptor subunit 1 ISO mRNA:increased expression:brain RGD PMID:18338268 RGD:2315462 NCBI chr 6:29,602,238...29,633,183
Ensembl chr 6:29,555,629...29,633,976 		JBrowse link
G GAD1 glutamate decarboxylase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:32165127 NCBI chr 2:170,813,210...170,861,151
Ensembl chr 2:170,813,213...170,861,151 		JBrowse link
G GAL galanin and GMAP prepropeptide ISO
EXP		 mRNA:decreased expression:paraventricular hypothalamic nucleus, solitary tract nucleus
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:10818254 PMID:15275958 RGD:1624333 NCBI chr11:68,684,544...68,691,175
Ensembl chr11:68,683,779...68,691,175 		JBrowse link
G GATA5 GATA binding protein 5 susceptibility IAGP DNA:SNPs:intron, exon:rs6061245,rs6587239 (human) RGD PMID:26617239 RGD:11343485 NCBI chr20:62,463,497...62,475,995
Ensembl chr20:62,463,497...62,475,995 		JBrowse link
G GCG glucagon EXP CTD Direct Evidence: marker/mechanism CTD PMID:22228705 NCBI chr 2:162,142,882...162,152,247
Ensembl chr 2:162,142,882...162,152,404 		JBrowse link
G GCH1 GTP cyclohydrolase 1 treatment
sexual_dimorphism 		EXP
IMP
ISO
IAGP		 CTD Direct Evidence: marker/mechanism
mRNA:decreased expression:aorta
DNA:SNV:3' UTR: 59038C>T (rs841, +243C>T) (human)		 CTD
RGD		 PMID:12855421 PMID:12925450 PMID:33857222 PMID:15167268 PMID:12623977 More... RGD:401700397, RGD:401700394, RGD:329970288, RGD:329961330, RGD:329961329 NCBI chr14:54,842,017...54,902,826
Ensembl chr14:54,842,008...54,902,826 		JBrowse link
G GCK glucokinase susceptibility IAGP RGD PMID:9324112 RGD:1581877 NCBI chr 7:44,143,213...44,189,439
Ensembl chr 7:44,143,213...44,198,170 		JBrowse link
G GCLC glutamate-cysteine ligase catalytic subunit EXP CTD Direct Evidence: marker/mechanism CTD PMID:22228705 NCBI chr 6:53,497,341...53,545,101
Ensembl chr 6:53,497,341...53,616,970 		JBrowse link
G GHSR growth hormone secretagogue receptor ISO associated with Obesity RGD PMID:24760503 RGD:12910115 NCBI chr 3:172,443,291...172,448,456
Ensembl chr 3:172,443,291...172,448,456 		JBrowse link
G GJA1 gap junction protein alpha 1 treatment ISO
EXP		 CTD Direct Evidence: marker/mechanism|therapeutic CTD
RGD		 PMID:16448880 PMID:36720419 PMID:16448880 PMID:23719203 RGD:7207810, RGD:8662439 NCBI chr 6:121,435,646...121,449,727
Ensembl chr 6:121,435,595...121,449,727 		JBrowse link
G GJA4 gap junction protein alpha 4 EXP CTD Direct Evidence: marker/mechanism CTD PMID:16448880 NCBI chr 1:34,792,999...34,795,747
Ensembl chr 1:34,792,999...34,795,747 		JBrowse link
G GJA5 gap junction protein alpha 5 treatment ISO
EXP		 CTD Direct Evidence: marker/mechanism
protein:decreased expression:artery endothelium 		CTD
RGD		 PMID:19109587 PMID:19686729 PMID:11821709 RGD:7207417, RGD:7207848 NCBI chr 1:147,756,199...147,773,351
Ensembl chr 1:147,756,199...147,773,362 		JBrowse link
G GJC1 gap junction protein gamma 1 EXP CTD Direct Evidence: therapeutic CTD PMID:19109587 NCBI chr17:44,794,104...44,831,364
Ensembl chr17:44,798,448...44,830,816 		JBrowse link
G GLCE glucuronic acid epimerase IAGP DNA:SNP: : rs3865014 (human) RGD PMID:27699767 RGD:401717571 NCBI chr15:69,160,635...69,272,207
Ensembl chr15:69,160,584...69,272,217 		JBrowse link
G GLP1R glucagon like peptide 1 receptor EXP CTD Direct Evidence: marker/mechanism CTD PMID:22228705 NCBI chr 6:39,048,781...39,091,303
Ensembl chr 6:39,048,781...39,091,303 		JBrowse link
G GNAI2 G protein subunit alpha i2 treatment ISO RGD PMID:27912212 PMID:15106810 RGD:13507308, RGD:13508592 NCBI chr 3:50,227,068...50,263,358
Ensembl chr 3:50,226,292...50,259,362 		JBrowse link
G GNAI3 G protein subunit alpha i3 treatment ISO RGD PMID:15106810 RGD:13508592 NCBI chr 1:109,548,615...109,600,195
Ensembl chr 1:109,548,615...109,600,195 		JBrowse link
G GNAS GNAS complex locus IAGP
EXP
IEA		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:9506701 PMID:12215464 PMID:15118671 RGD:1580404, RGD:1331525 NCBI chr20:58,839,748...58,911,192
Ensembl chr20:58,839,718...58,911,192 		JBrowse link
G GNB3 G protein subunit beta 3 no_association
susceptibility		 IAGP
EXP		 DNA:polymorphism: :multiple (human)
CTD Direct Evidence: marker/mechanism
DNA:SNP:cds: 825C>T (human)
DNA:SNP:cds:825C>T (human)		 CTD
RGD		 PMID:15961981 PMID:16141801 PMID:16908025 PMID:11230982 PMID:10526907 RGD:2313206, RGD:1580408, RGD:1580410 NCBI chr12:6,840,925...6,847,393
Ensembl chr12:6,839,954...6,847,393 		JBrowse link
G GNRH1 gonadotropin releasing hormone 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:6350720 NCBI chr 8:25,419,258...25,425,040
Ensembl chr 8:25,419,258...25,424,654 		JBrowse link
G GP1BA glycoprotein Ib platelet subunit alpha EXP CTD Direct Evidence: marker/mechanism CTD PMID:22352330 NCBI chr17:4,932,277...4,935,023
Ensembl chr17:4,932,277...4,935,023 		JBrowse link
G GPX1 glutathione peroxidase 1 treatment IEP
ISO
EXP		 protein,mRNA:decreased_expression:mononuclear_cells:after treatment, activity increased but mRNA expression decreased further
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:21593737 PMID:17198913 PMID:31572179 PMID:21210316 PMID:23752977 RGD:1600704, RGD:329956417, RGD:11353777, RGD:11352825 NCBI chr 3:49,357,176...49,358,353
Ensembl chr 3:49,357,174...49,358,605 		JBrowse link
G GPX3 glutathione peroxidase 3 treatment
susceptibility		 ISO
IAGP		 DNA:SNP: : rs3828599 (human)
DNA:SNP: :rs3828599 (human)		 RGD PMID:23528973 PMID:21933611 PMID:32034489 RGD:401793732, RGD:401827166, RGD:401827127 NCBI chr 5:151,020,591...151,028,988
Ensembl chr 5:151,020,591...151,028,988 		JBrowse link
G GRK2 G protein-coupled receptor kinase 2 treatment ISO
EXP		 protein:increased expression:lymphocyte, vascular associated smooth muscle cell
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:11901213 PMID:10642272 PMID:23913704 RGD:1625788, RGD:13792716 NCBI chr11:67,266,473...67,286,556
Ensembl chr11:67,266,473...67,286,556 		JBrowse link
G GRK3 G protein-coupled receptor kinase 3 ISO mRNA:increased expression:heart left ventricle, kidney (rat) RGD PMID:26248277 RGD:11535540 NCBI chr22:25,564,675...25,729,294
Ensembl chr22:25,564,675...25,729,294 		JBrowse link
G GRK5 G protein-coupled receptor kinase 5 ISO mRNA:increased expression:heart left ventricle, kidney (rat) RGD PMID:26248277 RGD:11535540 NCBI chr10:119,207,571...119,459,745
Ensembl chr10:119,207,571...119,459,745 		JBrowse link
G GSK3B glycogen synthase kinase 3 beta treatment ISO
EXP		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:22982863 PMID:22982863 RGD:10045670 NCBI chr 3:119,821,321...120,094,447
Ensembl chr 3:119,821,321...120,094,994 		JBrowse link
G GSR glutathione-disulfide reductase treatment IEP
ISO		 protein,mRNA:decreased_expression:mononuclear_cells:after treatment, activity increased but mRNA expression decreased further RGD PMID:17198913 PMID:23528973 RGD:1600704, RGD:401793732 NCBI chr 8:30,678,066...30,727,846
Ensembl chr 8:30,678,066...30,727,846 		JBrowse link
G GSTA5 glutathione S-transferase alpha 5 EXP CTD Direct Evidence: marker/mechanism CTD PMID:22228705 NCBI chr 6:52,831,692...52,846,245
Ensembl chr 6:52,831,655...52,840,843 		JBrowse link
G GSTM1 glutathione S-transferase mu 1 ISO mRNA:decreased expression:kidney (rat) RGD PMID:15699453 PMID:12624007 RGD:7495838, RGD:631154 NCBI chr 1:109,687,817...109,693,745
Ensembl chr 1:109,687,814...109,709,039 		JBrowse link
G GSTM2 glutathione S-transferase mu 2 treatment ISO RGD PMID:18008142 PMID:23528973 RGD:2302178, RGD:401793732 NCBI chr 1:109,668,057...109,683,997
Ensembl chr 1:109,668,022...109,709,551 		JBrowse link
G GSTP1 glutathione S-transferase pi 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:24915237 NCBI chr11:67,583,812...67,586,653
Ensembl chr11:67,583,742...67,586,656 		JBrowse link
G GSTT1 glutathione S-transferase theta 1 IAGP
EXP		 associated with scleroderma, systemic;DNA:deletion: :
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:22228705 PMID:11477481 PMID:32034489 RGD:5490587, RGD:401827127
G GSTT2 glutathione S-transferase theta 2 (gene/pseudogene) EXP CTD Direct Evidence: marker/mechanism CTD PMID:22228705 NCBI chr22:23,980,134...23,983,915
Ensembl chr22:23,980,058...23,983,915 		JBrowse link
G GUCY1A1 guanylate cyclase 1 soluble subunit alpha 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:18339647 NCBI chr 4:155,666,848...155,737,059
Ensembl chr 4:155,666,726...155,737,059 		JBrowse link
G H2AX H2A.X variant histone treatment ISO RGD PMID:24239235 RGD:8693672 NCBI chr11:119,093,874...119,095,465
Ensembl chr11:119,093,874...119,095,465 		JBrowse link
G HAVCR1 hepatitis A virus cellular receptor 1 ISO protein:increased expression:urine RGD PMID:23085980 RGD:7245484 NCBI chr 5:157,029,413...157,069,407
Ensembl chr 5:157,026,742...157,069,396 		JBrowse link
G HDAC6 histone deacetylase 6 ISO protein:increased expression, activity:heart: RGD PMID:23868068 RGD:9681716 NCBI chr  X:48,801,398...48,824,982
Ensembl chr  X:48,801,377...48,824,982 		JBrowse link
G HDAC8 histone deacetylase 8 ISO protein:decreased expression:heart (mouse, rat) RGD PMID:28567090 RGD:13208602 NCBI chr  X:72,329,516...72,572,843
Ensembl chr  X:72,329,516...72,573,101 		JBrowse link
G HGF hepatocyte growth factor susceptibility IAGP DNA:polymorphism:intron13:C/A RGD PMID:15127882 RGD:1642064 NCBI chr 7:81,699,010...81,770,047
Ensembl chr 7:81,699,010...81,770,438 		JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha ISO
EXP
IEP		 protein:increased expression:brain
CTD Direct Evidence: therapeutic
Hypertension, Pregnancy-Induced;mRNA, protein:increased expression:placenta
associated with Hypercholesterolemia;protein:increased expression:aorta		 CTD
RGD		 PMID:22349312 PMID:16955051 PMID:15862159 PMID:11882589 RGD:1626317, RGD:1626322, RGD:1626330 NCBI chr14:61,695,513...61,748,258
Ensembl chr14:61,695,513...61,748,259 		JBrowse link
G HK2 hexokinase 2 treatment ISO RGD PMID:31572179 RGD:329956417 NCBI chr 2:74,834,127...74,893,359
Ensembl chr 2:74,834,127...74,893,359 		JBrowse link
G HLA-DQA1 major histocompatibility complex, class II, DQ alpha 1 IAGP DNA:polymorphisms (human) RGD PMID:11798899 RGD:5147807 NCBI chr 6:32,637,406...32,655,272
Ensembl chr 6:32,628,179...32,647,062 		JBrowse link
G HMGB1 high mobility group box 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:32147540 NCBI chr13:30,456,704...30,617,597
Ensembl chr13:30,456,704...30,617,597 		JBrowse link
G HMOX1 heme oxygenase 1 susceptibility
treatment		 IAGP
EXP
IMP
ISO		 CTD Direct Evidence: marker/mechanism|therapeutic CTD
RGD		 PMID:16959961 PMID:22349312 PMID:22352330 PMID:12872043 PMID:20836698 More... RGD:1598400, RGD:10755717, RGD:1580453 NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214 		JBrowse link
G HP haptoglobin susceptibility
onset		 IAGP
EXP
ISO		 DNA:polymorphism
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:16597321 PMID:7606649 PMID:23401751 PMID:8228210 RGD:1626351, RGD:7241867, RGD:1626352 NCBI chr16:72,054,505...72,061,055
Ensembl chr16:72,054,505...72,061,055 		JBrowse link
G HRH2 histamine receptor H2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:30310171 NCBI chr 5:175,658,071...175,710,756
Ensembl chr 5:175,658,030...175,710,756 		JBrowse link
G HRH3 histamine receptor H3 ISO
EXP		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:9050021 PMID:9050021 RGD:1626409 NCBI chr20:62,214,960...62,220,278
Ensembl chr20:62,214,960...62,220,278 		JBrowse link
G HSD11B1 hydroxysteroid 11-beta dehydrogenase 1 susceptibility EXP
IAGP		 CTD Direct Evidence: marker/mechanism
DNA:SNP:5'utr: (rs846910) (human)		 CTD
RGD		 PMID:9683905 PMID:15199296 PMID:21786805 PMID:15452033 RGD:329902060 NCBI chr 1:209,686,179...209,734,929
Ensembl chr 1:209,686,178...209,734,949 		JBrowse link
G HSD11B2 hydroxysteroid 11-beta dehydrogenase 2 IAGP
ISO
EXP		 apparent mineralocorticoid excess syndrome, OMIM:218030; DNA:transition:CDS:945C->T, amino acid R279C
CTD Direct Evidence: marker/mechanism
associated with Diabetes Mellitus, Experimental;mRNA:decreased expression:kidney		 CTD
RGD		 PMID:7670488 PMID:9683905 PMID:9707624 PMID:11082157 PMID:9683587 More... RGD:1625078, RGD:13800514, RGD:2308925 NCBI chr16:67,429,801...67,437,553
Ensembl chr16:67,430,652...67,437,553 		JBrowse link
G HSD17B4 hydroxysteroid 17-beta dehydrogenase 4 ISO mRNA:decreased expression:renal cortex (rat) RGD PMID:18430809 RGD:2292646 NCBI chr 5:119,452,497...119,542,332
Ensembl chr 5:119,452,465...119,637,199 		JBrowse link
G HSD3B1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 susceptibility ISO
IAGP		 mRNA:increased expression:hypothalamus (rat)
DNA:polymorphism:exon		 RGD PMID:16116051 PMID:12054649 RGD:1599701, RGD:1626438 NCBI chr 1:119,507,203...119,515,058
Ensembl chr 1:119,507,198...119,515,054 		JBrowse link
G HSD3B2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 ISO mRNA:decreased expression:ovary (rat) RGD PMID:19228890 RGD:4761326 NCBI chr 1:119,414,931...119,423,034
Ensembl chr 1:119,414,931...119,423,035 		JBrowse link
G HSPA8 heat shock protein family A (Hsp70) member 8 IEP mRNA: increased expression: leukocyte RGD PMID:17341625 RGD:6480224 NCBI chr11:123,057,489...123,062,462
Ensembl chr11:123,057,489...123,063,230 		JBrowse link
G HSPD1 heat shock protein family D (Hsp60) member 1 ISO mRNA:increased expression:brain, blood vessel RGD PMID:15729290 PMID:18948349 RGD:1624213, RGD:10402862 NCBI chr 2:197,486,584...197,500,274
Ensembl chr 2:197,486,584...197,516,737 		JBrowse link
G HSPG2 heparan sulfate proteoglycan 2 ISO mRNA:increased expression:aorta RGD PMID:8225534 RGD:1624258 NCBI chr 1:21,822,244...21,937,310
Ensembl chr 1:21,822,244...21,937,310 		JBrowse link
G HTR1B 5-hydroxytryptamine receptor 1B ISO protein:increased expression:aorta RGD PMID:11882579 RGD:1626447 NCBI chr 6:77,460,924...77,463,491
Ensembl chr 6:77,460,924...77,463,491 		JBrowse link
G HTR2A 5-hydroxytryptamine receptor 2A no_association
susceptibility		 IAGP
IEA		 DNA:polymorphism: :g.102T>C
DNA:polymorphism: :102T>C		 RGD
GAD		 PMID:15659047 PMID:15118671 PMID:11378836 RGD:1624371, RGD:1331525, RGD:1624375 NCBI chr13:46,831,546...46,898,082
Ensembl chr13:46,831,546...46,897,076 		JBrowse link
G HTR2B 5-hydroxytryptamine receptor 2B EXP CTD Direct Evidence: marker/mechanism CTD PMID:8627522 NCBI chr 2:231,108,230...231,125,042
Ensembl chr 2:231,108,230...231,125,042 		JBrowse link
G HTRA1 HtrA serine peptidase 1 treatment IAGP
ISO		 associated with Macular Degeneration; DNA:snp:cds:g.102C>T (rs1049331) (human) RGD PMID:21682878 PMID:27847271 RGD:7394697, RGD:12910764 NCBI chr10:122,461,553...122,514,907
Ensembl chr10:122,458,551...122,514,907 		JBrowse link
G ICAM1 intercellular adhesion molecule 1 IEP
EXP		 associated with Diabetes Mellitus, Non-Insulin-Dependent;protein:increased expression:serum
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:12149661 PMID:12425201 PMID:18619052 RGD:2312765 NCBI chr19:10,271,120...10,286,615
Ensembl chr19:10,271,093...10,286,615 		JBrowse link
G IER3 immediate early response 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:20713914 NCBI chr 6:30,743,199...30,744,547
Ensembl chr 6:30,743,199...30,744,548 		JBrowse link
G IGF1 insulin like growth factor 1 severity IEP
EXP
ISO		 CTD Direct Evidence: marker/mechanism|therapeutic
mRNA:increased expression:aorta (rat)		 CTD
RGD		 PMID:19502719 PMID:22228705 PMID:16431135 PMID:8418983 PMID:15996002 RGD:1598427, RGD:12904968, RGD:1580474 NCBI chr12:102,395,874...102,481,839
Ensembl chr12:102,395,874...102,481,744 		JBrowse link
G IGF1R insulin like growth factor 1 receptor ISO protein:increased expression:aorta: RGD PMID:21854769 RGD:10046007 NCBI chr15:98,648,539...98,964,530
Ensembl chr15:98,648,539...98,964,530 		JBrowse link
G IGFBP2 insulin like growth factor binding protein 2 ISO mRNA, protein:decreased expression:liver, plasma RGD PMID:9396554 RGD:1626482 NCBI chr 2:216,632,828...216,664,436
Ensembl chr 2:216,632,828...216,664,436 		JBrowse link
G IKBKB inhibitor of nuclear factor kappa B kinase subunit beta treatment ISO
EXP		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:27659729 PMID:32147540 PMID:19246475 RGD:7495780 NCBI chr 8:42,271,302...42,332,460
Ensembl chr 8:42,271,302...42,332,460 		JBrowse link
G IL10 interleukin 10 ISO RGD PMID:19398662 RGD:2311047 NCBI chr 1:206,767,602...206,772,494
Ensembl chr 1:206,767,602...206,774,541 		JBrowse link
G IL17A interleukin 17A IEP protein:increased expression:blood serum (human) RGD PMID:26502942 RGD:329955577 NCBI chr 6:52,186,375...52,190,638
Ensembl chr 6:52,186,375...52,190,638 		JBrowse link
G IL1B interleukin 1 beta IEP
EXP
ISO		 associated with Obesity;protein:increased expression:plasma
CTD Direct Evidence: marker/mechanism
mRNA, protein:increased expression:aorta, plasma		 CTD
RGD		 PMID:27292124 PMID:27659729 PMID:27847271 PMID:32147540 PMID:32165127 More... RGD:1626638, RGD:7175338, RGD:1626635 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816 		JBrowse link
G IL1RN interleukin 1 receptor antagonist susceptibility ISO
IAGP		 DNA:polymorphisms RGD PMID:11585563 PMID:11840488 RGD:1626668, RGD:1626667 NCBI chr 2:113,099,360...113,134,014
Ensembl chr 2:113,099,315...113,134,016 		JBrowse link
G IL6 interleukin 6 susceptibility IDA
IEP
EXP
IAGP		 associated with Diabetes Mellitus, Non-Insulin-Dependent; protein:increased expression:extracellular space (human)
protein:increased expression:blood serum (human)
CTD Direct Evidence: marker/mechanism
associated with end stage renal disease; DNA:polymorphisms:promoter: -174G>C (human)		 CTD
RGD		 PMID:27292124 PMID:27659729 PMID:27847271 PMID:32147540 PMID:32165127 More... RGD:2307283, RGD:329955577, RGD:1580485 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
G IL6R interleukin 6 receptor severity IEP Hypertension, Pregnancy-Induced;protein:increased expression:serum RGD PMID:11778537 RGD:1625432 NCBI chr 1:154,405,343...154,469,450
Ensembl chr 1:154,405,193...154,469,450 		JBrowse link
G IL6ST interleukin 6 cytokine family signal transducer severity IEP Hypertension, Pregnancy-Induced;protein:increased expression:serum RGD PMID:11778537 RGD:1625432 NCBI chr 5:55,935,095...55,994,963
Ensembl chr 5:55,935,095...55,995,022 		JBrowse link
G INPPL1 inositol polyphosphate phosphatase like 1 IAGP
EXP		 DNA:SNPs: :rs2276047,snp8,rs9886(human)
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:15220217 PMID:15220217 RGD:1626127 NCBI chr11:72,223,563...72,239,147
Ensembl chr11:72,223,701...72,239,147 		JBrowse link
G INS insulin ISO
EXP		 CTD Direct Evidence: marker/mechanism
CTD Direct Evidence: marker/mechanism|therapeutic		 CTD
RGD		 PMID:9719048 PMID:18360027 PMID:29211853 PMID:9095092 RGD:6902896 NCBI chr11:2,159,779...2,161,209
Ensembl chr11:2,159,779...2,161,221 		JBrowse link
G INVS inversin IAGP associated with nephronophthisis 2; RGD PMID:19177160 RGD:155791686 NCBI chr 9:100,099,243...100,302,175
Ensembl chr 9:100,099,243...100,302,175 		JBrowse link
G ITGA9 integrin subunit alpha 9 susceptibility IAGP DNA:SNP: :rs155524(human) RGD PMID:20479155 RGD:13602005 NCBI chr 3:37,452,141...37,823,507
Ensembl chr 3:37,452,115...37,823,507 		JBrowse link
G ITGAV integrin subunit alpha V ISO protein:increased expression:artery RGD PMID:16380536 RGD:1627642 NCBI chr 2:186,590,056...186,680,901
Ensembl chr 2:186,590,010...186,680,901 		JBrowse link
G ITM2B integral membrane protein 2B EXP CTD Direct Evidence: marker/mechanism CTD PMID:22228705 NCBI chr13:48,233,206...48,270,357
Ensembl chr13:48,232,612...48,270,357 		JBrowse link
G JUN Jun proto-oncogene, AP-1 transcription factor subunit ISO
EXP		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:24039778 PMID:11358932 RGD:10047414 NCBI chr 1:58,780,791...58,784,047
Ensembl chr 1:58,776,845...58,784,048 		JBrowse link
G KCNA3 potassium voltage-gated channel subfamily A member 3 IEP protein:increased activity:T cell (human) RGD PMID:24524604 RGD:401794566 NCBI chr 1:110,653,560...110,674,940
Ensembl chr 1:110,653,560...110,674,940 		JBrowse link
G KCNA5 potassium voltage-gated channel subfamily A member 5 ISO mRNA:increased expression:heart RGD PMID:11358947 RGD:1627659 NCBI chr12:5,043,879...5,046,788
Ensembl chr12:5,043,879...5,046,788 		JBrowse link
G KCNAB1 potassium voltage-gated channel subfamily A regulatory beta subunit 1 ISO mRNA:increased expression:aorta, arteries (rat) RGD PMID:11358947 RGD:1627659 NCBI chr 3:156,118,211...156,539,138
Ensembl chr 3:156,037,701...156,538,756 		JBrowse link
G KCNJ1 potassium inwardly rectifying channel subfamily J member 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:22228705 NCBI chr11:128,838,020...128,867,296
Ensembl chr11:128,836,315...128,867,373 		JBrowse link
G KCNJ11 potassium inwardly rectifying channel subfamily J member 11 ISO RGD PMID:15964031 RGD:1598644 NCBI chr11:17,385,248...17,389,346
Ensembl chr11:17,365,172...17,389,331 		JBrowse link
G KCNJ8 potassium inwardly rectifying channel subfamily J member 8 ISO RGD PMID:16051697 RGD:1581698 NCBI chr12:21,764,955...21,774,706
Ensembl chr12:21,764,955...21,775,600 		JBrowse link
G KCNMB1 potassium calcium-activated channel subfamily M regulatory beta subunit 1 ISO
EXP
IAGP		 CTD Direct Evidence: marker/mechanism
mRNA, protein:increased expression:aorta, mesenteric artery		 CTD
RGD		 PMID:17700361 PMID:14551242 PMID:16814121 PMID:16293791 RGD:1298970, RGD:10412046, RGD:1581718 NCBI chr 5:170,374,671...170,389,367
Ensembl chr 5:170,374,671...170,389,634 		JBrowse link
G KCNN4 potassium calcium-activated channel subfamily N member 4 ameliorates IEP
ISO		 mRNA, protein:increased expression:CD4-positive, alpha-beta T cell (human)
associated with Cardiac Fibrosis
protein:increased activity:T cell (human)		 RGD PMID:26502942 PMID:25715999 PMID:24524604 RGD:329955577, RGD:401794570, RGD:401794566 NCBI chr19:43,766,533...43,780,973
Ensembl chr19:43,766,533...43,780,976 		JBrowse link
G KCNQ1 potassium voltage-gated channel subfamily Q member 1 ISO DNA:deletion:exon (rat) RGD PMID:16368876 RGD:1581602 NCBI chr11:2,445,008...2,849,105
Ensembl chr11:2,444,654...2,849,105 		JBrowse link
G KDR kinase insert domain receptor treatment ISO
IAGP		 DNA:polymorphism:cds:p.H472Q(human) RGD PMID:15838270 PMID:20630084 RGD:5684418, RGD:8552374 NCBI chr 4:55,078,481...55,125,595
Ensembl chr 4:55,078,481...55,125,595 		JBrowse link
G KIF6 kinesin family member 6 susceptibility IAGP DNA:SNP, haplotype: :rs20455 (p.W719R), rs6930913 (human) RGD PMID:34961832 RGD:243048456 NCBI chr 6:39,329,990...39,725,408
Ensembl chr 6:39,329,990...39,725,408 		JBrowse link
G KL klotho treatment ISO mRNA,protein:decreased expression:kidney: RGD PMID:10892340 PMID:21051829 PMID:23225045 RGD:1581732, RGD:10403063, RGD:10403062 NCBI chr13:33,016,243...33,066,143
Ensembl chr13:33,016,423...33,066,143 		JBrowse link
G KLK1 kallikrein 1 no_association
susceptibility		 IDA
EXP
IAGP
ISO		 CTD Direct Evidence: therapeutic
DNA:polymorphisms
mRNA:decreased expression:kidney		 CTD
RGD		 PMID:14568997 PMID:17272402 PMID:15167446 PMID:15905889 PMID:15809361 RGD:1641794, RGD:1581751, RGD:1641795, RGD:1358144 NCBI chr19:50,819,146...50,823,787
Ensembl chr19:50,819,146...50,823,787 		JBrowse link
G KLKB1 kallikrein B1 IEP associated with Diabetes Mellitus, Type 1; protein:increased expression:plasma: RGD PMID:12716755 RGD:7327151 NCBI chr 4:186,210,853...186,258,471
Ensembl chr 4:186,226,438...186,258,471 		JBrowse link
G KNG1 kininogen 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:7027322 NCBI chr 3:186,717,359...186,744,410
Ensembl chr 3:186,717,348...186,744,410 		JBrowse link
G KRAS KRAS proto-oncogene, GTPase ISO RGD PMID:15864294 RGD:1581757 NCBI chr12:25,205,246...25,250,929
Ensembl chr12:25,205,246...25,250,936 		JBrowse link
G KYNU kynureninase ISO RGD PMID:11924719 RGD:631322 NCBI chr 2:142,877,664...143,055,833
Ensembl chr 2:142,877,657...143,055,833 		JBrowse link
G LDHA lactate dehydrogenase A treatment ISO RGD PMID:31572179 RGD:329956417 NCBI chr11:18,394,563...18,408,425
Ensembl chr11:18,394,560...18,408,425 		JBrowse link
G LEP leptin IAGP
EXP
ISO		 DNA:SNPs: :
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:12050272 PMID:16827954 PMID:25205467 PMID:27226618 PMID:19204185 More... RGD:5128788, RGD:5128597 NCBI chr 7:128,241,278...128,257,629
Ensembl chr 7:128,241,278...128,257,629 		JBrowse link
G LEPR leptin receptor disease_progression IAGP
ISO
EXP		 DNA:polymorphisms:exons
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:22949526 PMID:10999797 PMID:27465994 RGD:5129161, RGD:12911217 NCBI chr 1:65,420,652...65,641,559
Ensembl chr 1:65,420,652...65,641,559 		JBrowse link
G LGALS3 galectin 3 treatment ISO RGD PMID:23117656 RGD:9685203 NCBI chr14:55,129,252...55,145,430
Ensembl chr14:55,124,110...55,145,423 		JBrowse link
G LHB luteinizing hormone subunit beta EXP CTD Direct Evidence: marker/mechanism CTD PMID:6350720 NCBI chr19:49,015,980...49,019,498
Ensembl chr19:49,015,980...49,017,091 		JBrowse link
G LIPE lipase E, hormone sensitive type IAGP gestational hypertension;DNA:polymorphism:promoter:-60C>G RGD PMID:17318300 RGD:1625026 NCBI chr19:42,401,514...42,427,388
Ensembl chr19:42,401,497...42,427,388 		JBrowse link
G LIPG lipase G, endothelial type ISO RGD PMID:15914124 RGD:1581875 NCBI chr18:49,561,479...49,599,185
Ensembl chr18:49,560,699...49,599,185 		JBrowse link
G LOC110673971 CYP11B2 promoter IAGP ClinVar Annotator: match by term: Aldosterone to renin ratio, increased ClinVar PMID:12213905 PMID:12788845 PMID:17003099 NCBI chr 8:142,917,842...142,919,862 JBrowse link
G LOX lysyl oxidase IDA RGD PMID:8562290 RGD:1581896 NCBI chr 5:122,063,195...122,078,259
Ensembl chr 5:122,063,195...122,078,413 		JBrowse link
G LPL lipoprotein lipase IAGP
EXP		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:22228705 PMID:16132104 RGD:1580535 NCBI chr 8:19,939,253...19,967,259
Ensembl chr 8:19,901,717...19,967,259 		JBrowse link
G LRP2 LDL receptor related protein 2 ISO protein:altered localization:apical plasma membrane RGD PMID:10919857 RGD:1641827 NCBI chr 2:169,127,109...169,362,534
Ensembl chr 2:169,127,109...169,362,534 		JBrowse link
G LTA lymphotoxin alpha no_association IAGP RGD PMID:15533732 RGD:1580415 NCBI chr 6:31,560,610...31,574,324
Ensembl chr 6:31,572,054...31,574,324 		JBrowse link
G LTF lactotransferrin EXP CTD Direct Evidence: therapeutic CTD PMID:24587916 NCBI chr 3:46,435,645...46,485,234
Ensembl chr 3:46,435,645...46,485,234 		JBrowse link
G MAP1LC3A microtubule associated protein 1 light chain 3 alpha ISO RGD PMID:23499735 RGD:11561939 NCBI chr20:34,546,844...34,560,345
Ensembl chr20:34,546,854...34,560,345 		JBrowse link
G MAPK8 mitogen-activated protein kinase 8 ISO RGD PMID:15302844 RGD:1582315 NCBI chr10:48,306,677...48,439,360
Ensembl chr10:48,306,639...48,439,360 		JBrowse link
G MAS1 MAS1 proto-oncogene, G protein-coupled receptor ISO associated with Sleep Apnea Syndromes RGD PMID:21040717 RGD:5129169 NCBI chr 6:159,888,787...159,917,447
Ensembl chr 6:159,890,988...159,917,447 		JBrowse link
G MC2R melanocortin 2 receptor EXP CTD Direct Evidence: marker/mechanism CTD PMID:11082157 NCBI chr18:13,882,044...13,915,707
Ensembl chr18:13,882,044...13,915,707 		JBrowse link
G MDH1 malate dehydrogenase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:22228705 NCBI chr 2:63,588,963...63,607,197
Ensembl chr 2:63,588,609...63,607,197 		JBrowse link
G MFN2 mitofusin 2 treatment ISO protein:decreased expression:aorta (rat) RGD PMID:27847271 PMID:25464244 RGD:12910764, RGD:13204764 NCBI chr 1:11,980,444...12,013,508
Ensembl chr 1:11,980,181...12,015,211 		JBrowse link
G MIF macrophage migration inhibitory factor ISO RGD PMID:19799867 RGD:4890974 NCBI chr22:23,894,383...23,895,223
Ensembl chr22:23,894,383...23,895,227 		JBrowse link
G MIR145 microRNA 145 IEP miRNA:increased expression:artery wall (human) RGD PMID:23339529 RGD:155260305 NCBI chr 5:149,430,646...149,430,733
Ensembl chr 5:149,430,646...149,430,733 		JBrowse link
G MIR214 microRNA 214 treatment ISO
IEP		 RNA:increased expression:kidney RGD PMID:30049682 PMID:30049682 RGD:38500245, RGD:38500245 NCBI chr 1:172,138,798...172,138,907
Ensembl chr 1:172,138,798...172,138,907 		JBrowse link
G MME membrane metalloendopeptidase treatment ISO RGD PMID:12011651 RGD:13801039 NCBI chr 3:155,024,202...155,183,729
Ensembl chr 3:155,024,124...155,183,704 		JBrowse link
G MMP1 matrix metallopeptidase 1 IDA
IEP		 protein:decreased expression:renal glomerulus (human) RGD PMID:15363819 PMID:19506087 RGD:1582532, RGD:2312464 NCBI chr11:102,789,919...102,798,160
Ensembl chr11:102,789,401...102,798,160 		JBrowse link
G MMP2 matrix metallopeptidase 2 ISO
EXP
IDA		 mRNA, protein:increased expression:kidney
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:18836702 PMID:17977875 PMID:16840178 RGD:2290351, RGD:1582612 NCBI chr16:55,478,830...55,506,691
Ensembl chr16:55,389,700...55,506,691 		JBrowse link
G MMP7 matrix metallopeptidase 7 treatment ISO RGD PMID:19398663 PMID:19398663 RGD:9685347, RGD:9685347 NCBI chr11:102,520,508...102,530,747
Ensembl chr11:102,520,508...102,530,750 		JBrowse link
G MMP9 matrix metallopeptidase 9 susceptibility IEP
EXP
IAGP
IDA
ISO		 protein:decreased expression:internal mammary artery
CTD Direct Evidence: marker/mechanism
associated with Aneurysm, Dissecting;DNA:polymorphism:promoter:-1562C>T		 CTD
RGD		 PMID:21051829 PMID:15363819 PMID:16780738 PMID:16840178 PMID:17977875 RGD:1582532, RGD:1642029, RGD:1582612, RGD:2290351 NCBI chr20:46,008,908...46,016,561
Ensembl chr20:46,008,908...46,016,561 		JBrowse link
G MOV10 Mov10 RNA helicase susceptibility IAGP DNA:SNP: :rs2932538(human) RGD PMID:24338417 RGD:13513987 NCBI chr 1:112,674,439...112,700,739
Ensembl chr 1:112,673,141...112,700,756 		JBrowse link
G MOXD2P monooxygenase DBH like 2, pseudogene ISO CTD Direct Evidence: marker/mechanism CTD PMID:3814904 NCBI chr 7:142,240,737...142,247,067
Ensembl chr 7:142,240,740...142,247,067 		JBrowse link
G MSX2 msh homeobox 2 ISO RGD PMID:18270471 RGD:5132616 NCBI chr 5:174,724,582...174,730,896
Ensembl chr 5:174,724,582...174,730,896 		JBrowse link
G MTOR mechanistic target of rapamycin kinase ISO
EXP		 protein:increased serine phosphorylation:kidney
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:19289642 PMID:23323219 RGD:10041025 NCBI chr 1:11,106,535...11,262,551
Ensembl chr 1:11,106,535...11,262,556 		JBrowse link
G MTPN myotrophin ISO RGD PMID:12419325 PMID:12031792 RGD:632799, RGD:1581046 NCBI chr 7:135,926,760...135,977,359
Ensembl chr 7:135,926,760...135,977,359 		JBrowse link
G MTR 5-methyltetrahydrofolate-homocysteine methyltransferase IAGP RGD PMID:15148588 RGD:1581050 NCBI chr 1:236,795,281...236,903,981
Ensembl chr 1:236,795,260...236,921,278 		JBrowse link
G MTTP microsomal triglyceride transfer protein onset IAGP DNA:polymorphism:promoter:-493G>T RGD PMID:16328015 RGD:1625485 NCBI chr 4:99,564,130...99,623,997
Ensembl chr 4:99,564,081...99,623,997 		JBrowse link
G MYBPH myosin binding protein H ISO DNA:missense mutations:cds:p.I?T, p.R?K (rat) RGD PMID:23460292 RGD:12802369 NCBI chr 1:203,167,811...203,179,214
Ensembl chr 1:203,167,811...203,175,826 		JBrowse link
G MYD88 MYD88 innate immune signal transduction adaptor EXP CTD Direct Evidence: marker/mechanism CTD PMID:27292124 NCBI chr 3:38,138,661...38,143,022
Ensembl chr 3:38,138,552...38,143,024 		JBrowse link
G MYH7 myosin heavy chain 7 ISO
EXP		 protein:decreased expression:heart left ventricle, arteriole
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:32147540 PMID:9686760 RGD:9835388 NCBI chr14:23,412,740...23,435,660
Ensembl chr14:23,412,740...23,435,660 		JBrowse link
G MYO6 myosin VI ISO protein:altered localization:renal proximal tubule, microvillus RGD PMID:16107581 RGD:2314963 NCBI chr 6:75,749,239...75,919,537
Ensembl chr 6:75,749,201...75,919,537 		JBrowse link
G MYOD1 myogenic differentiation 1 ISO mRNA:decreased expression:gastrocnemius RGD PMID:22076133 RGD:9686076 NCBI chr11:17,719,571...17,722,136
Ensembl chr11:17,719,571...17,722,136 		JBrowse link
G NCF1 neutrophil cytosolic factor 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:16331104 PMID:17324946 PMID:19018797 PMID:32165127 NCBI chr 7:74,774,011...74,789,315
Ensembl chr 7:74,774,011...74,789,315 		JBrowse link
G NCF2 neutrophil cytosolic factor 2 ISO protein:increased expression:heart left ventricle RGD PMID:19307699 RGD:2314430 NCBI chr 1:183,555,562...183,601,849
Ensembl chr 1:183,554,461...183,590,905 		JBrowse link
G NEDD4L NEDD4 like E3 ubiquitin protein ligase EXP CTD Direct Evidence: marker/mechanism CTD PMID:18524855 PMID:23348737 NCBI chr18:58,044,226...58,401,540
Ensembl chr18:58,044,226...58,401,540 		JBrowse link
G NFE2L2 NFE2 like bZIP transcription factor 2 treatment ISO
EXP		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:32165127 PMID:23775684 PMID:23528973 RGD:10412717, RGD:401793732 NCBI chr 2:177,230,303...177,264,727
Ensembl chr 2:177,218,667...177,392,756 		JBrowse link
G NFKBIA NFKB inhibitor alpha treatment ISO RGD PMID:19246475 RGD:7495780 NCBI chr14:35,401,513...35,404,749
Ensembl chr14:35,401,079...35,404,749 		JBrowse link
G NGF nerve growth factor ISO RGD PMID:10797303 RGD:5144109 NCBI chr 1:115,285,917...115,338,249
Ensembl chr 1:115,285,904...115,338,770 		JBrowse link
G NGFR nerve growth factor receptor ISO DNA,protein:missense mutation:CDS:c.28G>A, p.A10T (rat strains: SHR/Izm, SHRSP/Izm, WKHT) RGD PMID:8762194 RGD:5508800 NCBI chr17:49,495,293...49,515,008
Ensembl chr17:49,495,293...49,515,008 		JBrowse link
G NHERF1 NHERF family PDZ scaffold protein 1 ISO RGD PMID:15311100 RGD:1580741 NCBI chr17:74,748,628...74,769,353
Ensembl chr17:74,748,628...74,769,353 		JBrowse link
G NHERF2 NHERF family PDZ scaffold protein 2 ISO
EXP		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:22228705 PMID:15311100 RGD:1580741 NCBI chr16:2,026,902...2,039,026
Ensembl chr16:2,025,356...2,039,026 		JBrowse link
G NISCH nischarin ISO RGD PMID:12021582 RGD:1581128 NCBI chr 3:52,455,604...52,493,068
Ensembl chr 3:52,455,118...52,493,068 		JBrowse link
G NOS1 nitric oxide synthase 1 treatment ISO mRNA:decreased expression:bladder, penis RGD PMID:20494920 PMID:31489946 PMID:23201071 PMID:16093913 PMID:15913838 More... RGD:5132600, RGD:401793758, RGD:7257668, RGD:1581141, RGD:1581142, RGD:1581143, RGD:1642127 NCBI chr12:117,208,142...117,361,626
Ensembl chr12:117,208,142...117,452,170 		JBrowse link
G NOS2 nitric oxide synthase 2 IAGP
EXP
ISO		 CTD Direct Evidence: marker/mechanism
protein:increased expression, increased activity:kidney		 CTD
RGD		 PMID:18605955 PMID:25101153 PMID:27292124 PMID:11702222 PMID:15773227 RGD:1298023, RGD:1580264 NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529 		JBrowse link
G NOS3 nitric oxide synthase 3 treatment
no_association		 ISO
EXP
IAGP		 associated with Pregnancy Complications
CTD Direct Evidence: marker/mechanism|therapeutic
DNA:duplication, snp:intron, cds:IVS4?-?+27, p.E298D (human)
DNA:snp:cds:p.E298D (human)
protein:decreased phosphorylation:brain		 CTD
RGD		 PMID:11457755 PMID:12947532 PMID:16331104 PMID:19008412 PMID:19407804 More... RGD:2292113, RGD:401793758, RGD:13504683, RGD:13446414, RGD:1580278, RGD:1580271, RGD:1580282, RGD:4891993 NCBI chr 7:150,991,017...151,014,588
Ensembl chr 7:150,991,017...151,014,588 		JBrowse link
G NOX1 NADPH oxidase 1 ameliorates ISO RGD PMID:16246966 RGD:329955580 NCBI chr  X:100,843,324...100,874,359
Ensembl chr  X:100,843,324...100,874,359 		JBrowse link
G NOX4 NADPH oxidase 4 ISO
EXP		 protein:increased expression:aorta, vascular associated smooth muscle cell
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:27659729 PMID:27847271 PMID:32147540 PMID:18418428 PMID:26644237 RGD:2324669, RGD:11085830 NCBI chr11:89,324,353...89,589,557
Ensembl chr11:89,324,353...89,498,187 		JBrowse link
G NPHP3 nephrocystin 3 IAGP associated with nephronophthisis; RGD PMID:19177160 RGD:155791686 NCBI chr 3:132,680,609...132,722,409
Ensembl chr 3:132,680,609...132,722,432 		JBrowse link
G NPPA natriuretic peptide A ISO
ISS
EXP		 protein:increased expression:plasma:
CTD Direct Evidence: marker/mechanism|therapeutic		 MouseDO
CTD
RGD		 PMID:2526952 PMID:7839143 PMID:8188982 PMID:9869009 PMID:12940879 More... RGD:7248593 NCBI chr 1:11,845,709...11,847,783
Ensembl chr 1:11,845,709...11,848,345 		JBrowse link
G NPPB natriuretic peptide B susceptibility
treatment		 IAGP
EXP
ISO		 DNA:repeats
CTD Direct Evidence: marker/mechanism|therapeutic		 CTD
RGD		 PMID:9194512 PMID:19219041 PMID:24039778 PMID:30310171 PMID:32147540 More... RGD:1642191, RGD:5685657, RGD:70484 NCBI chr 1:11,857,464...11,858,945
Ensembl chr 1:11,857,464...11,858,945 		JBrowse link
G NPPC natriuretic peptide C severity IEP
IAGP		 associated with Pregnancy Complications;protein:increased expression:plasma RGD PMID:11775888 PMID:12452325 RGD:1642292, RGD:1580150 NCBI chr 2:231,921,809...231,926,396
Ensembl chr 2:231,921,809...231,926,396 		JBrowse link
G NPR1 natriuretic peptide receptor 1 ISO
EXP		 DNA:repeat:promoter: (rat)
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:20881240 PMID:12511524 RGD:628585 NCBI chr 1:153,678,688...153,693,992
Ensembl chr 1:153,678,688...153,693,992 		JBrowse link
G NPR3 natriuretic peptide receptor 3 IAGP DNA:snp:promoter:g.-55C>A (human) RGD PMID:12872042 RGD:1580175 NCBI chr 5:32,690,872...32,791,720
Ensembl chr 5:32,689,070...32,791,724 		JBrowse link
G NPTN neuroplastin EXP CTD Direct Evidence: marker/mechanism CTD PMID:22228705 NCBI chr15:73,560,014...73,633,389
Ensembl chr15:73,560,014...73,634,134 		JBrowse link
G NPY neuropeptide Y ISO
IAGP		 DNA:missense mutation:cds:p.L7P (human) RGD PMID:15699473 PMID:18835922 PMID:11689216 RGD:1357410, RGD:10448968, RGD:1580177 NCBI chr 7:24,284,190...24,291,862
Ensembl chr 7:24,284,188...24,291,862 		JBrowse link
G NPY1R neuropeptide Y receptor Y1 ISO RGD PMID:15699473 RGD:1357410 NCBI chr 4:163,323,962...163,344,689
Ensembl chr 4:163,323,962...163,344,832 		JBrowse link
G NQO1 NAD(P)H quinone dehydrogenase 1 treatment
susceptibility		 ISO
IAGP		 DNA:SNP,haplotype:: p.P187S (rs1800566) (human) RGD PMID:21502369 PMID:25529925 RGD:11035215, RGD:401827819 NCBI chr16:69,709,401...69,726,560
Ensembl chr16:69,706,996...69,726,668 		JBrowse link
G NR2F2 nuclear receptor subfamily 2 group F member 2 ISO RGD PMID:25687237 RGD:10401852 NCBI chr15:96,326,046...96,340,263
Ensembl chr15:96,325,938...96,340,263 		JBrowse link
G NR3C1 nuclear receptor subfamily 3 group C member 1 ISO
EXP		 associated with fetal nutrition disorder
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:18434569 PMID:20659135 PMID:20674672 PMID:20659135 RGD:4892208, RGD:7174714 NCBI chr 5:143,277,931...143,435,512
Ensembl chr 5:143,277,931...143,435,512 		JBrowse link
G NUDT1 nudix hydrolase 1 ISO RGD PMID:17280880 RGD:10449166 NCBI chr 7:2,242,226...2,251,145
Ensembl chr 7:2,242,226...2,251,146 		JBrowse link
G OGG1 8-oxoguanine DNA glycosylase susceptibility IAGP DNA:SNP,haplotype::p.S326C (rs1052133) (human) RGD PMID:25529925 RGD:401827819 NCBI chr 3:9,749,952...9,783,108
Ensembl chr 3:9,749,944...9,788,219 		JBrowse link
G OLR1 oxidized low density lipoprotein receptor 1 ISO
EXP		 mRNA:increased expression:aorta (rat)
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:22352330 PMID:9494115 RGD:633385 NCBI chr12:10,158,301...10,176,266
Ensembl chr12:10,158,301...10,172,138 		JBrowse link
G OPA1 OPA1 mitochondrial dynamin like GTPase ISO protein:increased expression:heart left ventricle (rat) RGD PMID:24388463 RGD:7800726 NCBI chr 3:193,593,208...193,697,811
Ensembl chr 3:193,593,144...193,697,811 		JBrowse link
G ORAI1 ORAI calcium release-activated calcium modulator 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19897708 NCBI chr12:121,626,530...121,643,109
Ensembl chr12:121,626,509...121,643,218 		JBrowse link
G OXSR1 oxidative stress responsive kinase 1 EXP CTD Direct Evidence: therapeutic CTD PMID:22949526 NCBI chr 3:38,164,063...38,255,484
Ensembl chr 3:38,165,089...38,255,484 		JBrowse link
G OXT oxytocin/neurophysin I prepropeptide ISO
EXP		 mRNA:decreased expression:paraventricular hypothalamic nucleus
CTD Direct Evidence: therapeutic		 CTD
RGD		 PMID:9334988 PMID:18562099 PMID:16157794 PMID:18562099 RGD:2304174, RGD:2304105 NCBI chr20:3,071,620...3,072,517
Ensembl chr20:3,071,620...3,072,517 		JBrowse link
G OXTR oxytocin receptor ISO mRNA:decreased expression:brainstem RGD PMID:16157794 RGD:2304174 NCBI chr 3:8,741,269...8,769,613
Ensembl chr 3:8,750,381...8,769,628 		JBrowse link
G PAPPA pappalysin 1 IEP associated with Pregnancy Complications, Cardiovascular;protein:decreased expression:serum RGD PMID:12224070 RGD:1642331 NCBI chr 9:116,153,791...116,402,321
Ensembl chr 9:116,153,791...116,402,321 		JBrowse link
G PDGFB platelet derived growth factor subunit B ISO RGD PMID:8869081 RGD:10449484 NCBI chr22:39,223,359...39,244,982
Ensembl chr22:39,223,359...39,244,982 		JBrowse link
G PDGFRA platelet derived growth factor receptor alpha ISO RGD PMID:1657776 RGD:11080972 NCBI chr 4:54,229,293...54,298,245
Ensembl chr 4:54,229,280...54,298,245 		JBrowse link
G PDGFRB platelet derived growth factor receptor beta ISO protein:increased tyrosine phosphorylation:glomerulus RGD PMID:12047046 PMID:1657776 RGD:2292214, RGD:11080972 NCBI chr 5:150,113,839...150,155,845
Ensembl chr 5:150,113,839...150,155,872 		JBrowse link
G PGF placental growth factor IEP associated with Pregnancy Complications, Cardiovascular;mRNA:decreased expression:placenta RGD PMID:12808329 RGD:1642387 NCBI chr14:74,941,830...74,955,764
Ensembl chr14:74,941,834...74,955,626 		JBrowse link
G PIK3R1 phosphoinositide-3-kinase regulatory subunit 1 ISO protein:decreased expression:ventricular myocyte (rat) RGD PMID:18300869 PMID:19015400 RGD:4108492, RGD:4108483 NCBI chr 5:68,215,756...68,301,821
Ensembl chr 5:68,215,740...68,301,821 		JBrowse link
G PIN1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 ISO RGD PMID:21810655 RGD:8693428 NCBI chr19:9,835,318...9,849,689
Ensembl chr19:9,835,257...9,849,689 		JBrowse link
G PKD1 polycystin 1, transient receptor potential channel interacting IAGP ClinVar Annotator: match by term: Hypertension ClinVar PMID:11115377 PMID:12482949 PMID:16430766 PMID:17574468 PMID:17582161 More... NCBI chr16:2,088,708...2,135,898
Ensembl chr16:2,088,708...2,135,898 		JBrowse link
G PKM pyruvate kinase M1/2 treatment ISO RGD PMID:31572179 RGD:329956417 NCBI chr15:72,199,029...72,231,591
Ensembl chr15:72,199,029...72,231,819 		JBrowse link
G PLAT plasminogen activator, tissue type EXP CTD Direct Evidence: marker/mechanism CTD PMID:22352330 NCBI chr 8:42,174,718...42,207,565
Ensembl chr 8:42,174,718...42,207,709 		JBrowse link
G PLCD1 phospholipase C delta 1 ISO protein:increased activity:aorta
protein:increased expression:aorta, arteriole, glomerulus		 RGD PMID:1313006 PMID:17198910 RGD:2300423, RGD:2300421 NCBI chr 3:38,007,496...38,029,642
Ensembl chr 3:38,007,496...38,029,642 		JBrowse link
G PLEKHA7 pleckstrin homology domain containing A7 ameliorates ISO RGD PMID:25136115 RGD:11079199 NCBI chr11:16,777,297...17,014,414
Ensembl chr11:16,777,297...17,014,415 		JBrowse link
G PLG plasminogen EXP CTD Direct Evidence: marker/mechanism CTD PMID:6383834 NCBI chr 6:160,702,193...160,754,097
Ensembl chr 6:160,702,194...160,754,097 		JBrowse link
G PNMT phenylethanolamine N-methyltransferase no_association ISO
IAGP		 protein:decreased activity:adrenal gland (rat)
DNA:snps:5' utr:g.-390G>A, g.-184G>A rs876493 (human)
DNA:snp:5' utr:g.-390G>A (human)		 RGD PMID:20378607 PMID:17645789 PMID:14553966 RGD:5130152, RGD:5130172, RGD:5130164 NCBI chr17:39,668,019...39,670,475
Ensembl chr17:39,667,981...39,670,475 		JBrowse link
G POMC proopiomelanocortin EXP CTD Direct Evidence: marker/mechanism|therapeutic CTD PMID:76749 PMID:187612 PMID:216942 PMID:323586 PMID:1316127 More... NCBI chr 2:25,160,860...25,168,580
Ensembl chr 2:25,160,853...25,168,903 		JBrowse link
G PON1 paraoxonase 1 IAGP DNA:SNP: :rs705379 (human) RGD PMID:32034489 RGD:401827127 NCBI chr 7:95,297,676...95,324,532
Ensembl chr 7:95,297,676...95,324,532 		JBrowse link
G POSTN periostin ISO associated with Renal Insufficiency, Chronic; protein:increased expression:left ventricle: RGD PMID:21712488 RGD:10041050 NCBI chr13:37,562,585...37,598,768
Ensembl chr13:37,562,583...37,598,844 		JBrowse link
G PPARA peroxisome proliferator activated receptor alpha treatment ISO
EXP		 mRNA:increased expression:skeletal muscle
CTD Direct Evidence: marker/mechanism|therapeutic		 CTD
RGD		 PMID:16054168 PMID:19834340 PMID:19763017 PMID:31489946 PMID:15967866 RGD:2313778, RGD:401793758, RGD:1580222 NCBI chr22:46,150,526...46,243,756
Ensembl chr22:46,150,521...46,243,755 		JBrowse link
G PPARG peroxisome proliferator activated receptor gamma IAGP
EXP
ISO
IMP		 CTD Direct Evidence: marker/mechanism|therapeutic
protein:decreased expression:rostral ventrolateral medulla (rat)
human gene in a mouse model		 CTD
RGD		 PMID:15199296 PMID:19666838 PMID:27292124 PMID:12923396 PMID:20404217 More... RGD:1580690, RGD:7175297, RGD:2301864, RGD:2301888, RGD:1580684 NCBI chr 3:12,287,368...12,434,344
Ensembl chr 3:12,287,368...12,434,356 		JBrowse link
G PPBP pro-platelet basic protein EXP CTD Direct Evidence: marker/mechanism CTD PMID:6192689 PMID:15513305 NCBI chr 4:73,986,439...73,988,190
Ensembl chr 4:73,985,966...73,988,276 		JBrowse link
G PPIA peptidylprolyl isomerase A HEP mRNA:increased expression:alveolar system (human) RGD PMID:32496587 RGD:150383342 NCBI chr 7:44,796,681...44,803,117
Ensembl chr 7:44,796,680...44,824,564 		JBrowse link
G PRKAG2 protein kinase AMP-activated non-catalytic subunit gamma 2 IAGP ClinVar Annotator: match by term: Hypertension ClinVar PMID:25741868 PMID:28492532 NCBI chr 7:151,556,127...151,877,115
Ensembl chr 7:151,556,124...151,877,214 		JBrowse link
G PRKAR1B protein kinase cAMP-dependent type I regulatory subunit beta ISO RGD PMID:11161799 RGD:619653 NCBI chr 7:549,197...728,934
Ensembl chr 7:549,197...727,650 		JBrowse link
G PRKCA protein kinase C alpha ISO RGD PMID:15792354 RGD:1581271 NCBI chr17:66,302,613...66,810,743
Ensembl chr17:66,302,613...66,810,743 		JBrowse link
G PRKCB protein kinase C beta ISO RGD PMID:15804434 RGD:1625513 NCBI chr16:23,835,983...24,220,611
Ensembl chr16:23,835,983...24,220,611 		JBrowse link
G PRKCD protein kinase C delta IEP
EXP
ISO		 protein:increased expression:heart, fibroblast
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:23973649 PMID:10756122 PMID:15792354 RGD:1642534, RGD:1581271 NCBI chr 3:53,161,209...53,192,717
Ensembl chr 3:53,156,009...53,192,717 		JBrowse link
G PRKCE protein kinase C epsilon ISO RGD PMID:15792354 RGD:1581271 NCBI chr 2:45,651,279...46,187,990
Ensembl chr 2:45,651,345...46,187,990 		JBrowse link
G PRKG1 protein kinase cGMP-dependent 1 ISO mRNA, protein:splice variant, alternative form:basilar artery RGD PMID:14512447 RGD:7775067 NCBI chr10:50,990,888...52,298,350
Ensembl chr10:50,990,888...52,298,423 		JBrowse link
G PRLHR prolactin releasing hormone receptor IAGP DNA:SNP, missense mutation:promoter, cds:-62G>A, 914C>T (p.P305L) (human) RGD PMID:14691196 RGD:1641832 NCBI chr10:118,589,997...118,595,648
Ensembl chr10:118,589,997...118,595,648 		JBrowse link
G PROC protein C, inactivator of coagulation factors Va and VIIIa EXP CTD Direct Evidence: marker/mechanism CTD PMID:22352330 NCBI chr 2:127,418,427...127,429,242
Ensembl chr 2:127,418,427...127,429,242 		JBrowse link
G PTEN phosphatase and tensin homolog EXP CTD Direct Evidence: marker/mechanism CTD PMID:15646324 NCBI chr10:87,863,625...87,971,930
Ensembl chr10:87,862,638...87,971,930 		JBrowse link
G PTGDS prostaglandin D2 synthase IEP protein:increased expression:serum, urine RGD PMID:11882588 RGD:1642584 NCBI chr 9:136,977,504...136,981,742
Ensembl chr 9:136,975,092...136,981,742 		JBrowse link
G PTGIS prostaglandin I2 synthase susceptibility IAGP
ISO		 mRNA:increased expression:aortic endothelial cell (rat)
DNA:repeat:promoter:g.-6(CCGCCAGCC)3-4 (human)
DNA:SNP:exon 8:g.1117C>A (rs6095558) (human)		 RGD PMID:12372404 PMID:18056786 PMID:10577996 PMID:17070428 RGD:1298040, RGD:401960082, RGD:401959586, RGD:401959383 NCBI chr20:49,503,874...49,568,137
Ensembl chr20:49,503,874...49,568,137 		JBrowse link
G PTGR1 prostaglandin reductase 1 ISO mRNA:decreased expression:rostral ventrolateral medulla, paraventricular nucleus of hypothalamus, nucleus of solitary tract (rat) RGD PMID:23172924 RGD:401959217 NCBI chr 9:111,549,722...111,599,647
Ensembl chr 9:111,549,722...111,599,893 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 ISO
EXP		 CTD Direct Evidence: marker/mechanism|therapeutic CTD
RGD		 PMID:14757778 PMID:15834289 PMID:20667508 PMID:22349312 PMID:16467505 More... RGD:1580671, RGD:1581285 NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922 		JBrowse link
G PTH parathyroid hormone IEP
EXP		 protein:increased expression:serum (human)
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:1930854 PMID:23460043 RGD:7242420 NCBI chr11:13,492,054...13,496,181
Ensembl chr11:13,492,054...13,496,181 		JBrowse link
G PTK2 protein tyrosine kinase 2 ISO protein:increased expression:aorta RGD PMID:12732587 PMID:21068519 RGD:729831, RGD:10041072 NCBI chr 8:140,657,900...141,002,079
Ensembl chr 8:140,657,900...141,002,216 		JBrowse link
G PTK2B protein tyrosine kinase 2 beta susceptibility IAGP
ISO		 DNA:polymorphism:promoter:-22A>G
protein:increased expression:aorta		 RGD PMID:18075463 PMID:21068519 RGD:2292575, RGD:10041072 NCBI chr 8:27,310,506...27,459,391
Ensembl chr 8:27,311,482...27,459,391 		JBrowse link
G PTPN1 protein tyrosine phosphatase non-receptor type 1 treatment EXP
ISO		 CTD Direct Evidence: therapeutic
associated with obesity		 CTD
RGD		 PMID:28899902 PMID:29859467 PMID:29562733 RGD:401976391, RGD:401976390 NCBI chr20:50,510,383...50,585,241
Ensembl chr20:50,510,321...50,585,241 		JBrowse link
G PTPRC protein tyrosine phosphatase receptor type C ameliorates ISO associated with Cardiac Fibrosis RGD PMID:25715999 RGD:401794570 NCBI chr 1:198,638,713...198,757,476
Ensembl chr 1:198,638,457...198,759,342 		JBrowse link
G PTPRD protein tyrosine phosphatase receptor type D treatment IAGP DNA:SNP:enhancer: (rs10739150) (human) RGD PMID:26425837 RGD:11085524 NCBI chr 9:8,314,246...10,613,002
Ensembl chr 9:8,314,246...10,613,002 		JBrowse link
G PTPRJ protein tyrosine phosphatase receptor type J ISO RGD PMID:15710778 RGD:1357414 NCBI chr11:47,980,559...48,170,839
Ensembl chr11:47,980,425...48,170,839 		JBrowse link
G PTPRU protein tyrosine phosphatase receptor type U susceptibility ISO RGD PMID:11086029 RGD:1642652 NCBI chr 1:29,236,522...29,326,800
Ensembl chr 1:29,236,516...29,326,813 		JBrowse link
G QDPR quinoid dihydropteridine reductase ISO protein:decreased expression:aorta smooth muscle (rat) RGD PMID:19743417 RGD:5128580 NCBI chr 4:17,486,395...17,512,090
Ensembl chr 4:17,460,261...17,512,206 		JBrowse link
G RAD51 RAD51 recombinase treatment ISO RGD PMID:24239235 RGD:8693672 NCBI chr15:40,694,733...40,732,340
Ensembl chr15:40,694,774...40,732,340 		JBrowse link
G RAG1 recombination activating 1 ISO RGD PMID:23364523 RGD:7207429 NCBI chr11:36,510,353...36,579,762
Ensembl chr11:36,510,372...36,593,156 		JBrowse link
G RALBP1 ralA binding protein 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:23821548 NCBI chr18:9,475,009...9,538,114
Ensembl chr18:9,475,009...9,538,114 		JBrowse link
G RAMP2 receptor activity modifying protein 2 susceptibility IAGP
ISO
IEP		 DNA:SNP:intron
mRNA, protein:increased expression:heart myocardium, aorta
associated with Pregnancy Complications		 RGD PMID:15797661 PMID:16450076 PMID:11600589 RGD:1642679, RGD:1625300, RGD:1642682 NCBI chr17:42,761,227...42,763,041
Ensembl chr17:42,758,447...42,763,041 		JBrowse link
G RASGRP3 RAS guanyl releasing protein 3 IAGP RGD PMID:19421330 RGD:2314812 NCBI chr 2:33,436,348...33,564,731
Ensembl chr 2:33,436,324...33,586,669 		JBrowse link
G RBFOX2 RNA binding fox-1 homolog 2 ISO mRNA, protein:splice variant, increased expression:mesenteric artery (rat) RGD PMID:28993448 RGD:329848961 NCBI chr22:35,738,736...36,028,824
Ensembl chr22:35,738,736...36,028,824 		JBrowse link
G RBP4 retinol binding protein 4 sexual_dimorphism
ameliorates		 IEP
ISO		 protein:increased expression:blood serum (human) RGD PMID:20798476 PMID:21365528 PMID:25911613 RGD:329845596, RGD:329853304, RGD:329845871 NCBI chr10:93,591,694...93,601,744
Ensembl chr10:93,591,687...93,601,744 		JBrowse link
G REG3G regenerating family member 3 gamma EXP CTD Direct Evidence: marker/mechanism CTD PMID:27798352 NCBI chr 2:79,025,702...79,028,501
Ensembl chr 2:79,025,686...79,028,505 		JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit ISO
EXP		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:19018797 PMID:27659729 PMID:32147540 PMID:16840655 RGD:2298761 NCBI chr11:65,653,601...65,663,857
Ensembl chr11:65,653,599...65,663,090 		JBrowse link
G REN renin treatment IAGP
ISO
EXP		 CTD Direct Evidence: marker/mechanism
protein:decreased activity:plasma (mouse)		 CTD
RGD		 PMID:45830 PMID:62162 PMID:998518 PMID:1071603 PMID:1149188 More... RGD:1580697, RGD:401793709, RGD:6892655, RGD:6784501, RGD:1580671 NCBI chr 1:204,154,819...204,166,337
Ensembl chr 1:204,154,819...204,190,324 		JBrowse link
G RESP18 regulated endocrine specific protein 18 ISO RGD PMID:29570433 RGD:14348960 NCBI chr 2:219,327,407...219,336,656
Ensembl chr 2:219,327,407...219,333,177 		JBrowse link
G RETN resistin IAGP DNA:SNP:3' utr:*62A>G (human) RGD PMID:12629116 RGD:1624968 NCBI chr19:7,669,049...7,670,455
Ensembl chr19:7,669,049...7,670,455 		JBrowse link
G RFFL ring finger and FYVE like domain containing E3 ubiquitin protein ligase ISO mRNA,protein:increased expression:heart RGD PMID:21357277 RGD:13442502 NCBI chr17:35,005,990...35,089,226
Ensembl chr17:35,005,990...35,089,319 		JBrowse link
G RGS2 regulator of G protein signaling 2 EXP
ISO		 CTD Direct Evidence: therapeutic CTD
RGD		 PMID:1798635 PMID:14608379 PMID:17986358 RGD:13524579, RGD:2289116 NCBI chr 1:192,809,039...192,812,275
Ensembl chr 1:192,809,039...192,812,275 		JBrowse link
G RGS4 regulator of G protein signaling 4 treatment ISO RGD PMID:21825230 RGD:7207400 NCBI chr 1:163,068,871...163,076,802
Ensembl chr 1:163,068,775...163,076,802 		JBrowse link
G RGS5 regulator of G protein signaling 5 treatment EXP
ISO		 CTD Direct Evidence: therapeutic CTD
RGD		 PMID:1798635 PMID:21825230 RGD:7207400 NCBI chr 1:163,142,299...163,321,735
Ensembl chr 1:163,111,121...163,321,791 		JBrowse link
G RHOA ras homolog family member A ISO protein:altered localization:mesenteric artery RGD PMID:17620967 RGD:1642801 NCBI chr 3:49,359,145...49,411,976
Ensembl chr 3:49,359,139...49,412,998 		JBrowse link
G RNLS renalase, FAD dependent amine oxidase IAGP
ISO		 associated with Diabetes Mellitus Type 2; DNA:SNPs: : rs2296545,rs2576178 (human)
associated with kidney Failure,Chronic;DNA:SNPs: : rs2576178, rs10887800 (human)		 RGD PMID:21964580 PMID:21178975 PMID:21617193 RGD:7327172, RGD:7327174, RGD:7327173 NCBI chr10:88,171,523...88,583,318
Ensembl chr10:88,273,864...88,584,530 		JBrowse link
G RNPEP arginyl aminopeptidase ISO protein:increased expression:adrenal gland, neurohypophysis RGD PMID:9660082 PMID:3001599 RGD:2325942, RGD:2325950 NCBI chr 1:201,982,648...202,006,143
Ensembl chr 1:201,982,372...202,006,147 		JBrowse link
G RPS6KB1 ribosomal protein S6 kinase B1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19289642 NCBI chr17:59,893,121...59,950,574
Ensembl chr17:59,893,046...59,950,574 		JBrowse link
G S100B S100 calcium binding protein B IEP protein:increased expression:serum RGD PMID:21130083 RGD:5508770 NCBI chr21:46,598,604...46,605,082
Ensembl chr21:46,598,604...46,605,208 		JBrowse link
G S1PR1 sphingosine-1-phosphate receptor 1 disease_progression ISO associated with SHRSP;mRNA,protein:increased expression, decreased expression:kidney (rat) RGD PMID:17938382 RGD:1643008 NCBI chr 1:101,236,899...101,242,313
Ensembl chr 1:101,236,865...101,243,713 		JBrowse link
G SCNN1A sodium channel epithelial 1 subunit alpha EXP CTD Direct Evidence: marker/mechanism CTD PMID:11752024 PMID:23348737 NCBI chr12:6,346,847...6,377,359
Ensembl chr12:6,346,843...6,377,730 		JBrowse link
G SCNN1B sodium channel epithelial 1 subunit beta EXP CTD Direct Evidence: marker/mechanism CTD PMID:15174897 PMID:15198480 PMID:19344079 NCBI chr16:23,278,231...23,381,294
Ensembl chr16:23,278,231...23,381,294 		JBrowse link
G SCNN1G sodium channel epithelial 1 subunit gamma EXP CTD Direct Evidence: marker/mechanism CTD PMID:15198480 NCBI chr16:23,182,745...23,216,883
Ensembl chr16:23,182,745...23,216,883 		JBrowse link
G SELP selectin P EXP CTD Direct Evidence: marker/mechanism CTD PMID:15513305 NCBI chr 1:169,588,849...169,630,124
Ensembl chr 1:169,588,849...169,630,193 		JBrowse link
G SERPINA1 serpin family A member 1 IEP protein:increased expression:urine RGD PMID:10353322 RGD:1643147 NCBI chr14:94,376,747...94,390,635
Ensembl chr14:94,376,747...94,390,693 		JBrowse link
G SERPINE1 serpin family E member 1 treatment IEP
ISO
EXP		 protein:increased expression:plasma (human)
mRNA:increased expression:kidney (SHRSP/A3N rat)
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:21051829 PMID:22352330 PMID:8355419 PMID:11907153 PMID:16645728 RGD:8547753, RGD:28912746, RGD:11081003 NCBI chr 7:101,127,104...101,139,247
Ensembl chr 7:101,127,104...101,139,247 		JBrowse link
G SERPINE2 serpin family E member 2 ISO mRNA, protein:increased expression:blood vessel RGD PMID:12524238 RGD:729767 NCBI chr 2:223,975,045...224,039,286
Ensembl chr 2:223,975,045...224,039,318 		JBrowse link
G SERPINF2 serpin family F member 2 IEP RGD PMID:9361364 RGD:1625531 NCBI chr17:1,742,871...1,755,265
Ensembl chr17:1,742,836...1,755,265 		JBrowse link
G SGK1 serum/glucocorticoid regulated kinase 1 susceptibility
no_association		 IAGP DNA:snps:exon, intron: (human)
DNA:SNP:exon, intron:no association with SNPs in codon 240 in exon 8, codon 398 in exon 12 or intron 6		 RGD PMID:16221215 PMID:15304560 RGD:1580968, RGD:1580969 NCBI chr 6:134,169,256...134,318,112
Ensembl chr 6:134,169,248...134,318,112 		JBrowse link
G SH2B3 SH2B adaptor protein 3 ISO RGD PMID:25776069 RGD:13442483 NCBI chr12:111,404,730...111,451,623
Ensembl chr12:111,405,923...111,451,623 		JBrowse link
G SIRT6 sirtuin 6 exacerbates ISO RGD PMID:30894089 RGD:155260334 NCBI chr19:4,174,109...4,182,563
Ensembl chr19:4,174,109...4,182,566 		JBrowse link
G SLC12A2 solute carrier family 12 member 2 ISO
EXP		 mRNA:increased expression:aorta
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:17259435 PMID:15020309 PMID:21814290 RGD:1580582, RGD:9587757 NCBI chr 5:128,083,766...128,189,677
Ensembl chr 5:128,083,766...128,189,677 		JBrowse link
G SLC12A3 solute carrier family 12 member 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:18480177 NCBI chr16:56,865,207...56,915,850
Ensembl chr16:56,865,207...56,915,850 		JBrowse link
G SLC26A4 solute carrier family 26 member 4 ISO RGD PMID:17120771 RGD:7411553 NCBI chr 7:107,660,828...107,717,809
Ensembl chr 7:107,660,828...107,717,809 		JBrowse link
G SLC2A1 solute carrier family 2 member 1 ISO protein:increased expression:renal glomerulus RGD PMID:12771048 RGD:12879474 NCBI chr 1:42,925,353...42,958,868
Ensembl chr 1:42,925,353...42,958,893 		JBrowse link
G SLC2A3 solute carrier family 2 member 3 ISO RGD PMID:7598707 RGD:1642812 NCBI chr12:7,919,230...7,936,187
Ensembl chr12:7,919,230...8,019,007 		JBrowse link
G SLC4A4 solute carrier family 4 member 4 ISO protein:increased expression:kidney cortex RGD PMID:15340004 RGD:1600028 NCBI chr 4:71,062,660...71,572,083
Ensembl chr 4:71,062,667...71,572,087 		JBrowse link
G SLC5A2 solute carrier family 5 member 2 ISO RGD PMID:14506074 RGD:1599050 NCBI chr16:31,483,123...31,490,769
Ensembl chr16:31,483,002...31,490,860 		JBrowse link
G SLC6A18 solute carrier family 6 member 18 EXP CTD Direct Evidence: marker/mechanism CTD PMID:15121838 NCBI chr 5:1,225,381...1,246,189
Ensembl chr 5:1,225,381...1,246,189 		JBrowse link
G SLC6A19 solute carrier family 6 member 19 ISO mRNA:increased expression RGD PMID:17264310 RGD:1600036 NCBI chr 5:1,201,595...1,225,111
Ensembl chr 5:1,201,595...1,225,111 		JBrowse link
G SLC6A2 solute carrier family 6 member 2 IAGP
EXP		 DNA:polymorphism:1287G>A
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:22533655 PMID:17124432 RGD:1624279 NCBI chr16:55,655,988...55,706,192
Ensembl chr16:55,655,988...55,707,645 		JBrowse link
G SLC6A3 solute carrier family 6 member 3 ISO protein:increased expression:caudate-putamen RGD PMID:9074541 RGD:1625656 NCBI chr 5:1,392,794...1,445,440
Ensembl chr 5:1,392,794...1,445,440 		JBrowse link
G SLC8A1 solute carrier family 8 member A1 ISO
IAGP		 DNA:snps:intron:g.-23200T>C, g.-23181T>C (human)
DNA:SNP: :1784C>T		 RGD PMID:16343576 PMID:15785003 PMID:15824464 RGD:1598724, RGD:1580732, RGD:1580586 NCBI chr 2:40,097,270...40,512,435
Ensembl chr 2:40,097,270...40,611,053 		JBrowse link
G SLC9A3 solute carrier family 9 member A3 ISO RGD PMID:12372791 RGD:727447 NCBI chr 5:470,456...524,449
Ensembl chr 5:470,456...524,449 		JBrowse link
G SOD1 superoxide dismutase 1 treatment ISO
EXP
IMP
IEP		 associated with Hydronephrosis
CTD Direct Evidence: marker/mechanism|therapeutic
human gene in a rat model
mRNA:decreased expression:rostral ventrolateral medulla (rat)
protein,mRNA:decreased_expression:mononuclear_cells:after treatment, activity increased but mRNA expression decreased further		 CTD
RGD		 PMID:9024144 PMID:25101153 PMID:32165127 PMID:19403858 PMID:31572179 More... RGD:2312366, RGD:329956417, RGD:1580833, RGD:1581232, RGD:1580833, RGD:1600704 NCBI chr21:31,659,693...31,668,931
Ensembl chr21:31,659,666...31,668,931 		JBrowse link
G SOD2 superoxide dismutase 2 IDA
EXP
ISO		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:11834524 PMID:21593737 PMID:25101153 PMID:16716903 PMID:16716903 RGD:1580833, RGD:1580833 NCBI chr 6:159,669,069...159,762,281
Ensembl chr 6:159,669,069...159,762,529 		JBrowse link
G SOD3 superoxide dismutase 3 ISO
EXP		 CTD Direct Evidence: marker/mechanism|therapeutic CTD
RGD		 PMID:16864745 PMID:17023265 PMID:12600899 PMID:16864745 RGD:1580845, RGD:1581232 NCBI chr 4:24,795,573...24,800,842
Ensembl chr 4:24,789,912...24,800,842 		JBrowse link
G SQSTM1 sequestosome 1 ISO protein:decreased expression:brain RGD PMID:23499735 RGD:11561939 NCBI chr 5:179,806,393...179,838,078
Ensembl chr 5:179,806,398...179,838,078 		JBrowse link
G SRC SRC proto-oncogene, non-receptor tyrosine kinase ISO RGD PMID:16157790 RGD:1601372 NCBI chr20:37,344,699...37,406,050
Ensembl chr20:37,344,685...37,406,050 		JBrowse link
G SRF serum response factor ISO RGD PMID:16822834 RGD:1580749 NCBI chr 6:43,171,269...43,181,506
Ensembl chr 6:43,171,269...43,181,506 		JBrowse link
G SST somatostatin ISO protein:altered expression:stomach RGD PMID:17928643 RGD:2303191 NCBI chr 3:187,668,912...187,670,394
Ensembl chr 3:187,668,912...187,670,394 		JBrowse link
G STIM1 stromal interaction molecule 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19897708 NCBI chr11:3,854,604...4,093,210
Ensembl chr11:3,854,527...4,093,210 		JBrowse link
G STK11 serine/threonine kinase 11 EXP CTD Direct Evidence: marker/mechanism CTD PMID:19289642 NCBI chr19:1,205,778...1,228,431
Ensembl chr19:1,177,558...1,228,431 		JBrowse link
G STK39 serine/threonine kinase 39 EXP CTD Direct Evidence: therapeutic CTD PMID:22949526 NCBI chr 2:167,954,022...168,247,595
Ensembl chr 2:167,954,020...168,247,595 		JBrowse link
G STS steroid sulfatase ISO protein:increased expression:multiple organs RGD PMID:8539776 RGD:1601393 NCBI chr  X:7,147,290...7,354,641
Ensembl chr  X:7,147,237...7,804,358 		JBrowse link
G TAC3 tachykinin precursor 3 ISO protein:increased expression:supraoptic nucleus, medulla oblongata RGD PMID:2478257 RGD:2305983 NCBI chr12:57,010,000...57,016,529
Ensembl chr12:57,010,000...57,028,883 		JBrowse link
G TACR1 tachykinin receptor 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21294877 NCBI chr 2:75,046,463...75,199,520
Ensembl chr 2:75,046,463...75,199,520 		JBrowse link
G TACR3 tachykinin receptor 3 ISO RGD PMID:2471579 RGD:2305984 NCBI chr 4:103,586,031...103,719,985
Ensembl chr 4:103,586,031...103,719,985 		JBrowse link
G TBXAS1 thromboxane A synthase 1 ISO associated with hyperinsulinism RGD PMID:9370383 PMID:16192456 RGD:1601472, RGD:1601439 NCBI chr 7:139,778,242...140,020,293
Ensembl chr 7:139,777,051...140,020,325 		JBrowse link
G TF transferrin IEP protein:decreased expression RGD PMID:14974364 RGD:1601524 NCBI chr 3:133,661,998...133,796,641
Ensembl chr 3:133,746,040...133,796,641 		JBrowse link
G TGFB1 transforming growth factor beta 1 ISO
IEP
EXP
IEA		 protein:increased expression:vascular associated smooth muscle cell
protein:increased expression:blood serum (human)
mRNA:increased expression:kidney (SHRSP/A3N rat)
CTD Direct Evidence: marker/mechanism
protein:increased expression:renal glomerulus 		CTD
RGD		 PMID:11682445 PMID:19018797 PMID:17364610 PMID:26502942 PMID:11907153 More... RGD:1601552, RGD:329955577, RGD:28912746, RGD:30296650, RGD:12879474, RGD:1331525 NCBI chr19:41,330,323...41,353,922
Ensembl chr19:41,301,587...41,353,922 		JBrowse link
G TGFB3 transforming growth factor beta 3 no_association IAGP DNA:polymorphism, SNPs RGD PMID:15924806 RGD:1625704 NCBI chr14:75,958,097...75,983,011
Ensembl chr14:75,958,097...75,983,011 		JBrowse link
G TGM2 transglutaminase 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:17898543 NCBI chr20:38,127,385...38,168,475
Ensembl chr20:38,127,385...38,166,578 		JBrowse link
G TH tyrosine hydroxylase susceptibility IAGP
EXP
ISO		 DNA:polymorphism:intron:g.1090T>C rs2070762 (human)
CTD Direct Evidence: marker/mechanism
mRNA:increased expression:brain		 CTD
RGD		 PMID:27659729 PMID:32147540 PMID:32165127 PMID:16636198 PMID:16650497 RGD:1601631, RGD:1601630 NCBI chr11:2,163,929...2,171,815
Ensembl chr11:2,163,929...2,171,815 		JBrowse link
G THBD thrombomodulin treatment ISO
IEP		 associated with Experimental Diabetes Mellitus
protein:decreased expression:plasma
protein:increased expression:plasma		 RGD PMID:14737039 PMID:16095049 PMID:12611420 PMID:17401180 RGD:1601646, RGD:5685017, RGD:1601652, RGD:1601636 NCBI chr20:23,045,633...23,049,672
Ensembl chr20:23,045,633...23,049,672 		JBrowse link
G TIMP1 TIMP metallopeptidase inhibitor 1 ISO
EXP
IEP		 mRNA, protein:increased expression:kidney
CTD Direct Evidence: marker/mechanism
protein:decreased expression:glomerulus		 CTD
RGD		 PMID:21051829 PMID:17977875 PMID:19506087 RGD:2290351, RGD:2312464 NCBI chr  X:47,582,436...47,586,789
Ensembl chr  X:47,582,408...47,586,789 		JBrowse link
G TJP2 tight junction protein 2 ISO protein:decreased expression:brain RGD PMID:17234953 RGD:1600163 NCBI chr 9:69,121,264...69,255,208
Ensembl chr 9:69,121,264...69,274,615 		JBrowse link
G TLR4 toll like receptor 4 EXP CTD Direct Evidence: marker/mechanism CTD PMID:27292124 PMID:32147540 NCBI chr 9:117,704,403...117,724,735
Ensembl chr 9:117,704,175...117,724,735 		JBrowse link
G TNF tumor necrosis factor ameliorates
treatment		 IAGP
ISO
EXP		 associated with Cardiac Fibrosis
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:18605955 PMID:27292124 PMID:27659729 PMID:27847271 PMID:32147540 More... RGD:1580312, RGD:401794570, RGD:1357163, RGD:1580207 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
G TNFRSF11B TNF receptor superfamily member 11b severity IEP protein:increased expression:serum RGD PMID:22050177 RGD:7205512 NCBI chr 8:118,923,557...118,951,885
Ensembl chr 8:118,923,557...118,951,885 		JBrowse link
G TP53 tumor protein p53 EXP CTD Direct Evidence: marker/mechanism CTD PMID:22228705 NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,546 		JBrowse link
G TPM1 tropomyosin 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:22228705 NCBI chr15:63,042,747...63,071,915
Ensembl chr15:63,042,620...63,071,915 		JBrowse link
G TRH thyrotropin releasing hormone ISO
EXP		 protein:decreased expression:diencephalon
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:6350720 PMID:17227965 RGD:1600406 NCBI chr 3:129,974,720...129,977,935
Ensembl chr 3:129,974,688...129,977,935 		JBrowse link
G TRHR thyrotropin releasing hormone receptor IAGP RGD PMID:11566956 RGD:1580744 NCBI chr 8:109,086,585...109,121,565
Ensembl chr 8:109,086,585...109,121,565 		JBrowse link
G TRPC3 transient receptor potential cation channel subfamily C member 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:17351372 NCBI chr 4:121,874,481...121,952,060
Ensembl chr 4:121,874,481...121,952,060 		JBrowse link
G TRPC5 transient receptor potential cation channel subfamily C member 5 EXP CTD Direct Evidence: marker/mechanism CTD PMID:17351372 NCBI chr  X:111,768,011...112,082,776
Ensembl chr  X:111,768,011...112,082,776 		JBrowse link
G UCN urocortin IEP
EXP		 associated with Pregnancy Complications;protein:increased expression:plasma
CTD Direct Evidence: therapeutic		 CTD
RGD		 PMID:20237592 PMID:16915033 RGD:1642775 NCBI chr 2:27,307,400...27,308,445
Ensembl chr 2:27,307,400...27,308,445 		JBrowse link
G UCN2 urocortin 2 IDA human protein in rat model RGD PMID:19204182 RGD:5508437 NCBI chr 3:48,561,718...48,563,781
Ensembl chr 3:48,561,718...48,563,781 		JBrowse link
G UCP1 uncoupling protein 1 IAGP DNA:polymorphism: :-3826A>G (human) RGD PMID:17635070 RGD:2313626 NCBI chr 4:140,559,431...140,568,961
Ensembl chr 4:140,559,431...140,568,961 		JBrowse link
G UCP2 uncoupling protein 2 treatment IAGP
EXP
ISO		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:16685210 PMID:15106800 PMID:20404217 RGD:1580794, RGD:7175297 NCBI chr11:73,974,672...73,983,202
Ensembl chr11:73,974,061...73,982,843 		JBrowse link
G UCP3 uncoupling protein 3 ISO RGD PMID:10994754 RGD:1580795 NCBI chr11:74,000,277...74,009,085
Ensembl chr11:74,000,277...74,009,085 		JBrowse link
G UGCG UDP-glucose ceramide glucosyltransferase treatment ISO RGD PMID:23528973 RGD:401793732 NCBI chr 9:111,896,814...111,935,369
Ensembl chr 9:111,896,814...111,935,369 		JBrowse link
G UMOD uromodulin EXP CTD Direct Evidence: marker/mechanism CTD PMID:22228705 NCBI chr16:20,333,051...20,356,301
Ensembl chr16:20,333,051...20,356,301 		JBrowse link
G UTS2 urotensin 2 IEP
EXP		 protein:increased expression:plasma
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:16160878 PMID:15201550 RGD:1580808 NCBI chr 1:7,847,612...7,913,249
Ensembl chr 1:7,843,083...7,853,512 		JBrowse link
G UTS2R urotensin 2 receptor ISO RGD PMID:14621188 RGD:1580812 NCBI chr17:82,371,765...82,377,458
Ensembl chr17:82,371,765...82,377,458 		JBrowse link
G VAV3 vav guanine nucleotide exchange factor 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21115475 NCBI chr 1:107,571,161...107,965,180
Ensembl chr 1:107,571,161...107,965,180 		JBrowse link
G VCAM1 vascular cell adhesion molecule 1 disease_progression ISO
EXP
IEP		 mRNA:increased expression:multiple organs
associated with SHRSP;mRNA,protein:increased expression:kidney, membrane fraction (rat)
CTD Direct Evidence: marker/mechanism
associated with Diabetes Mellitus, Type1; protein:increased expression:serum:		 CTD
RGD		 PMID:11834524 PMID:19018797 PMID:19080338 PMID:17938382 PMID:20569722 RGD:2313107, RGD:1643008, RGD:7241235 NCBI chr 1:100,719,742...100,739,045
Ensembl chr 1:100,719,742...100,739,045 		JBrowse link
G VDR vitamin D receptor EXP CTD Direct Evidence: marker/mechanism CTD PMID:11335187 NCBI chr12:47,841,537...47,904,994
Ensembl chr12:47,841,537...47,943,048 		JBrowse link
G VEGFA vascular endothelial growth factor A treatment IEP
IMP		 associated with Prostatic Neoplasms RGD PMID:16164572 PMID:20630084 RGD:1580573, RGD:8552374 NCBI chr 6:43,770,211...43,786,487
Ensembl chr 6:43,770,184...43,786,487 		JBrowse link
G VHL von Hippel-Lindau tumor suppressor IAGP RGD PMID:12500216 RGD:1580371 NCBI chr 3:10,141,778...10,153,667
Ensembl chr 3:10,141,778...10,153,676 		JBrowse link
G VWF von Willebrand factor treatment EXP
ISO		 CTD Direct Evidence: marker/mechanism
associated with Experimental Diabetes Mellitus		 CTD
RGD		 PMID:12149661 PMID:12425201 PMID:22352330 PMID:14737039 RGD:1601646 NCBI chr12:5,948,877...6,124,670
Ensembl chr12:5,948,877...6,124,770 		JBrowse link
G WNK1 WNK lysine deficient protein kinase 1 IAGP
EXP		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:22949526 PMID:16301342 RGD:1580829 NCBI chr12:752,579...911,452
Ensembl chr12:752,579...911,452 		JBrowse link
G WNK4 WNK lysine deficient protein kinase 4 no_association ISO
EXP
IAGP		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:22949526 PMID:12642508 PMID:15110905 RGD:629611, RGD:1580830 NCBI chr17:42,780,610...42,797,066
Ensembl chr17:42,780,610...42,797,066 		JBrowse link
G XDH xanthine dehydrogenase treatment ISO
IAGP
IMP		 DNA:SNPs:exon, intron:47686C>T, 69901A>C, 67873A>C (p.N1109T) (human) RGD PMID:23746952 PMID:12826072 PMID:18712049 PMID:18728266 RGD:7247630, RGD:13210518, RGD:7247654, RGD:7247653 NCBI chr 2:31,334,321...31,414,742
Ensembl chr 2:31,334,321...31,414,742 		JBrowse link
G XRCC1 X-ray repair cross complementing 1 susceptibility IAGP DNA:SNP,haplotypes: p.R194W, p.R399Q (rs1799782, rs25487) (human) RGD PMID:25529925 RGD:401827819 NCBI chr19:43,543,311...43,575,527
Ensembl chr19:43,543,311...43,580,473 		JBrowse link
G XRCC3 X-ray repair cross complementing 3 susceptibility IAGP DNA:SNP,haplotype:cd: p.T241M (rs861539) (human) RGD PMID:25529925 RGD:401827819 NCBI chr14:103,697,617...103,715,451
Ensembl chr14:103,697,609...103,715,504 		JBrowse link
G YWHAZ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein zeta treatment ISO RGD PMID:22984478 RGD:9587480 NCBI chr 8:100,916,523...100,953,382
Ensembl chr 8:100,916,523...100,953,388 		JBrowse link
benign hypertensive renal disease term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MAP3K7 mitogen-activated protein kinase kinase kinase 7 IEP protein:increased expression:cortex of kidney (human) RGD PMID:34584221 RGD:155791449 NCBI chr 6:90,513,579...90,587,072
Ensembl chr 6:90,513,573...90,587,086 		JBrowse link
Diastolic Hypertension, Resistance to term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KCNIP1 potassium voltage-gated channel interacting protein 1 IAGP ClinVar Annotator: match by term: Hypertension, diastolic, resistance to ClinVar PMID:15057310 PMID:16155733 NCBI chr 5:170,353,487...170,736,632
Ensembl chr 5:170,353,487...170,736,632 		JBrowse link
G KCNMB1 potassium calcium-activated channel subfamily M regulatory beta subunit 1 IAGP
EXP		 ClinVar Annotator: match by term: Hypertension, diastolic, resistance to
CTD Direct Evidence: marker/mechanism		 OMIM
ClinVar
CTD		 PMID:15057310 PMID:16155733 NCBI chr 5:170,374,671...170,389,367
Ensembl chr 5:170,374,671...170,389,634 		JBrowse link
Dursun Syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G G6PC3 glucose-6-phosphatase catalytic subunit 3 IAGP ClinVar Annotator: match by term: Dursun syndrome ClinVar PMID:25741868 PMID:28492532 NCBI chr17:44,070,673...44,076,344
Ensembl chr17:44,070,620...44,082,151 		JBrowse link
G LOC130060959 ATAC-STARR-seq lymphoblastoid active region 12250 IAGP ClinVar Annotator: match by term: Dursun syndrome ClinVar PMID:25741868 PMID:28492532 NCBI chr17:44,071,022...44,071,261 JBrowse link
eclampsia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G IL6 interleukin 6 treatment ISO RGD PMID:27106269 RGD:11062145 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
essential hypertension term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACSM3 acyl-CoA synthetase medium chain family member 3 no_association IAGP RGD PMID:11592044 RGD:1579978 NCBI chr16:20,674,405...20,797,581
Ensembl chr16:20,610,243...20,797,581 		JBrowse link
G ADD1 adducin 1 IAGP
EXP		 CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Hypertension, salt-sensitive essential, susceptibility to		 OMIM
CTD
ClinVar		 PMID:9149697 PMID:9607177 PMID:10024330 PMID:10523341 PMID:11882573 More... NCBI chr 4:2,843,844...2,930,062
Ensembl chr 4:2,843,844...2,930,076 		JBrowse link
G AGT angiotensinogen IAGP
EXP		 ClinVar Annotator: match by term: Hypertension, essential, susceptibility to
ClinVar Annotator: match by term: Essential hypertension, genetic
CTD Direct Evidence: marker/mechanism		 ClinVar
CTD		 PMID:1394429 PMID:7649545 PMID:7883995 PMID:8348146 PMID:8513325 More... NCBI chr 1:230,702,523...230,745,583
Ensembl chr 1:230,690,776...230,745,576 		JBrowse link
G AGTR1 angiotensin II receptor type 1 treatment IMP
IAGP
EXP		 ClinVar Annotator: match by term: Essential hypertension, genetic
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Hypertension, essential, susceptibility to		 ClinVar
CTD
OMIM
RGD		 PMID:8021009 PMID:9084931 PMID:15042429 PMID:16116425 PMID:25741868 More... RGD:10047396 NCBI chr 3:148,697,903...148,743,003
Ensembl chr 3:148,697,784...148,743,008 		JBrowse link
G AIF1 allograft inflammatory factor 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:34453990 NCBI chr 6:31,615,234...31,617,015
Ensembl chr 6:31,615,217...31,617,021 		JBrowse link
G ATP1B1 ATPase Na+/K+ transporting subunit beta 1 IAGP
EXP		 CTD Direct Evidence: marker/mechanism OMIM
CTD		 NCBI chr 1:169,106,690...169,132,719
Ensembl chr 1:169,105,697...169,310,992 		JBrowse link
G ATP2A2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 susceptibility IAGP DNA:polymorphism:exon:p.A724A (c.2171G>A)(human) RGD PMID:20687374 RGD:13507310 NCBI chr12:110,280,616...110,351,093
Ensembl chr12:110,280,756...110,351,093 		JBrowse link
G ATP5PF ATP synthase peripheral stalk subunit F6 IEP protein:increased expression:plasma (human) RGD PMID:14654753 RGD:13800915 NCBI chr21:25,724,500...25,735,653
Ensembl chr21:25,716,503...25,735,673 		JBrowse link
G CALY calcyon neuron specific vesicular protein EXP CTD Direct Evidence: marker/mechanism CTD PMID:30753204 NCBI chr10:133,324,072...133,336,896
Ensembl chr10:133,324,072...133,336,935 		JBrowse link
G CAT catalase IAGP RGD PMID:15735318 RGD:1581147 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060 		JBrowse link
G CDCA3 cell division cycle associated 3 IAGP ClinVar Annotator: match by term: Hypertension, essential, susceptibility to ClinVar PMID:9425898 PMID:10477144 PMID:10523525 PMID:10770297 PMID:10770309 More... NCBI chr12:6,844,798...6,851,286
Ensembl chr12:6,844,793...6,851,292 		JBrowse link
G CYBA cytochrome b-245 alpha chain EXP CTD Direct Evidence: marker/mechanism CTD PMID:34453990 NCBI chr16:88,643,289...88,651,053
Ensembl chr16:88,643,275...88,651,083 		JBrowse link
G CYBB cytochrome b-245 beta chain EXP CTD Direct Evidence: marker/mechanism CTD PMID:34453990 NCBI chr  X:37,780,059...37,813,461
Ensembl chr  X:37,780,018...37,813,461 		JBrowse link
G CYP3A5 cytochrome P450 family 3 subfamily A member 5 susceptibility IAGP
EXP		 ClinVar Annotator: match by term: Hypertension, salt-sensitive essential, susceptibility to
CTD Direct Evidence: marker/mechanism		 ClinVar
CTD
OMIM		 PMID:11279519 PMID:11740341 PMID:12065767 PMID:12754175 PMID:15492926 NCBI chr 7:99,648,194...99,679,996
Ensembl chr 7:99,648,194...99,679,996 		JBrowse link
G ECE1 endothelin converting enzyme 1 susceptibility EXP
IAGP		 CTD Direct Evidence: marker/mechanism CTD
OMIM		 NCBI chr 1:21,217,250...21,345,504
Ensembl chr 1:21,217,247...21,345,572 		JBrowse link
G ELN elastin ISS OMIM:145500 | OMIM:603918 | OMIM:604329 | OMIM:607329 | OMIM:608742 | OMIM:610261 | OMIM:610262 | OMIM:610948 | OMIM:611014 MouseDO NCBI chr 7:74,028,173...74,069,907
Ensembl chr 7:74,027,789...74,069,907 		JBrowse link
G FFAR2 free fatty acid receptor 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:34453990 NCBI chr19:35,448,257...35,451,767
Ensembl chr19:35,443,907...35,451,767 		JBrowse link
G FFAR3 free fatty acid receptor 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:34453990 NCBI chr19:35,358,151...35,360,489
Ensembl chr19:35,358,460...35,360,489 		JBrowse link
G FGFR2 fibroblast growth factor receptor 2 sexual_dimorphism ISO mRNA, protein:decreased expression:inferior vagus X ganglion, nucleus of solitary tract (rat) RGD PMID:31626954 RGD:155791444 NCBI chr10:121,478,330...121,598,458
Ensembl chr10:121,478,332...121,598,458 		JBrowse link
G FTO FTO alpha-ketoglutarate dependent dioxygenase IGI DNA:SNP: :rs8050136 (human) RGD PMID:23691120 RGD:329845889 NCBI chr16:53,703,963...54,121,941
Ensembl chr16:53,701,692...54,158,512 		JBrowse link
G GATA5 GATA binding protein 5 ISS
ISO		 OMIM:145500 | OMIM:603918 | OMIM:604329 | OMIM:607329 | OMIM:608742 | OMIM:610261 | OMIM:610262 | OMIM:610948 | OMIM:611014 MouseDO
RGD		 PMID:26617239 RGD:11343485 NCBI chr20:62,463,497...62,475,995
Ensembl chr20:62,463,497...62,475,995 		JBrowse link
G GNB3 G protein subunit beta 3 IAGP
EXP
IGI		 ClinVar Annotator: match by term: Hypertension, essential, susceptibility to
CTD Direct Evidence: marker/mechanism
DNA:SNP: :rs5443, rs1129649 (human)		 ClinVar
OMIM
CTD
RGD		 PMID:9425898 PMID:10477144 PMID:10523525 PMID:10770297 PMID:10770309 More... RGD:329845889 NCBI chr12:6,840,925...6,847,393
Ensembl chr12:6,839,954...6,847,393 		JBrowse link
G GRK4 G protein-coupled receptor kinase 4 susceptibility IAGP DNA:SNP,haplotypes:cds: RGD PMID:15097232 RGD:1598505 NCBI chr 4:2,963,571...3,040,760
Ensembl chr 4:2,963,571...3,040,760 		JBrowse link
G HAVCR1 hepatitis A virus cellular receptor 1 IEP protein:increased expression:urine: RGD PMID:22923545 RGD:7245500 NCBI chr 5:157,029,413...157,069,407
Ensembl chr 5:157,026,742...157,069,396 		JBrowse link
G HCAR3 hydroxycarboxylic acid receptor 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:34453990 NCBI chr12:122,714,756...122,716,811
Ensembl chr12:122,714,756...122,716,811 		JBrowse link
G HMGB1 high mobility group box 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:34453990 NCBI chr13:30,456,704...30,617,597
Ensembl chr13:30,456,704...30,617,597 		JBrowse link
G HSD11B1 hydroxysteroid 11-beta dehydrogenase 1 susceptibility IAGP DNA:SNP:insertion: ins4436A (rs45487298) (human) RGD PMID:26671915 RGD:11353457 NCBI chr 1:209,686,179...209,734,929
Ensembl chr 1:209,686,178...209,734,949 		JBrowse link
G IL1B interleukin 1 beta EXP CTD Direct Evidence: marker/mechanism CTD PMID:34453990 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816 		JBrowse link
G LCN2 lipocalin 2 IEP protein:increased expression:urine: RGD PMID:22923545 RGD:7245500 NCBI chr 9:128,149,453...128,153,453
Ensembl chr 9:128,149,071...128,153,453 		JBrowse link
G MIR126 microRNA 126 IEP RNA:decreased expression:peripheral blood mononuclear cell RGD PMID:24794206 RGD:401851039 NCBI chr 9:136,670,602...136,670,686
Ensembl chr 9:136,670,602...136,670,686 		JBrowse link
G NCF1 neutrophil cytosolic factor 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:34453990 NCBI chr 7:74,774,011...74,789,315
Ensembl chr 7:74,774,011...74,789,315 		JBrowse link
G NOS3 nitric oxide synthase 3 IAGP
ISS
EXP		 DNA:snp:cds:p.E298D (human)
OMIM:145500 | OMIM:603918 | OMIM:604329 | OMIM:607329 | OMIM:608742 | OMIM:610261 | OMIM:610262 | OMIM:610948 | OMIM:611014
CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Essential hypertension
DNA:repeats:intron:IVS13+?-?dupCA (human)		 MouseDO
CTD
ClinVar
RGD		 PMID:25741868 PMID:11394896 PMID:9084930 RGD:1580280, RGD:1580277 NCBI chr 7:150,991,017...151,014,588
Ensembl chr 7:150,991,017...151,014,588 		JBrowse link
G NPPB natriuretic peptide B IEP protein:increased expression:plasma: RGD PMID:9350073 RGD:7246914 NCBI chr 1:11,857,464...11,858,945
Ensembl chr 1:11,857,464...11,858,945 		JBrowse link
G NPR2 natriuretic peptide receptor 2 IAGP DNA:repeat:intron:IVS2+150(GT)10-11 (human) RGD PMID:10082481 RGD:1580772 NCBI chr 9:35,791,591...35,809,731
Ensembl chr 9:35,791,003...35,809,732 		JBrowse link
G OCLN occludin EXP CTD Direct Evidence: marker/mechanism CTD PMID:34453990 NCBI chr 5:69,492,547...69,558,104
Ensembl chr 5:69,492,292...69,558,104 		JBrowse link
G PHACTR1 phosphatase and actin regulator 1 susceptibility IAGP DNA:SNP::g.12903725A>G (rs9349379) (human) RGD PMID:34758666 RGD:401900745 NCBI chr 6:12,716,767...13,287,837
Ensembl chr 6:12,716,312...13,290,446 		JBrowse link
G PTGIS prostaglandin I2 synthase IAGP
EXP		 ClinVar Annotator: match by term: Essential hypertension
ClinVar Annotator: match by term: Essential hypertension | ClinVar Annotator: match by term: Essential hypertension, genetic
CTD Direct Evidence: marker/mechanism		 ClinVar
CTD
OMIM		 PMID:12372404 PMID:25741868 NCBI chr20:49,503,874...49,568,137
Ensembl chr20:49,503,874...49,568,137 		JBrowse link
G PTPN1 protein tyrosine phosphatase non-receptor type 1 susceptibility IAGP DNA:SNPs::g.54281T>A, 15/37C>A (human) RGD PMID:20101100 RGD:401959376 NCBI chr20:50,510,383...50,585,241
Ensembl chr20:50,510,321...50,585,241 		JBrowse link
G RARRES2 retinoic acid receptor responder 2 IEP protein:increased expression:serum: RGD PMID:24047472 RGD:15036820 NCBI chr 7:150,338,329...150,341,629
Ensembl chr 7:150,338,317...150,341,662 		JBrowse link
G RBP4 retinol binding protein 4 disease_progression IEP protein:increased expression:blood plasma (human)
protein:increased expression:blood serum (human)		 RGD PMID:31865725 PMID:19556974 RGD:329845583, RGD:329845861 NCBI chr10:93,591,694...93,601,744
Ensembl chr10:93,591,687...93,601,744 		JBrowse link
G REN renin IDA RGD PMID:1152295 RGD:125097505 NCBI chr 1:204,154,819...204,166,337
Ensembl chr 1:204,154,819...204,190,324 		JBrowse link
G RGS5 regulator of G protein signaling 5 IAGP
EXP		 CTD Direct Evidence: marker/mechanism OMIM
CTD		 NCBI chr 1:163,142,299...163,321,735
Ensembl chr 1:163,111,121...163,321,791 		JBrowse link
G RNLS renalase, FAD dependent amine oxidase IAGP DNA:SNPs: :rs2576178, rs2296545,rs2114406 (human) RGD PMID:17216203 RGD:7327177 NCBI chr10:88,171,523...88,583,318
Ensembl chr10:88,273,864...88,584,530 		JBrowse link
G SLC12A3 solute carrier family 12 member 3 severity IAGP DNA:missense mutation:cds:p.R904Q (human)
DNA:snp:intron:g.1784C>T (human)		 RGD PMID:15480096 PMID:15824464 RGD:1580589, RGD:1580586 NCBI chr16:56,865,207...56,915,850
Ensembl chr16:56,865,207...56,915,850 		JBrowse link
G TH tyrosine hydroxylase EXP CTD Direct Evidence: marker/mechanism CTD PMID:34453990 NCBI chr11:2,163,929...2,171,815
Ensembl chr11:2,163,929...2,171,815 		JBrowse link
G TJP1 tight junction protein 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:34453990 NCBI chr15:29,699,367...29,969,049
Ensembl chr15:29,699,367...29,968,915 		JBrowse link
G TLR2 toll like receptor 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:34453990 NCBI chr 4:153,684,280...153,710,637
Ensembl chr 4:153,684,050...153,706,260 		JBrowse link
G TLR4 toll like receptor 4 EXP CTD Direct Evidence: marker/mechanism CTD PMID:34453990 NCBI chr 9:117,704,403...117,724,735
Ensembl chr 9:117,704,175...117,724,735 		JBrowse link
G TNF tumor necrosis factor EXP CTD Direct Evidence: marker/mechanism CTD PMID:34453990 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
G UMOD uromodulin IAGP ClinVar Annotator: match by term: Essential hypertension ClinVar NCBI chr16:20,333,051...20,356,301
Ensembl chr16:20,333,051...20,356,301 		JBrowse link
G ZSCAN25 zinc finger and SCAN domain containing 25 IAGP ClinVar Annotator: match by term: Hypertension, salt-sensitive essential, susceptibility to ClinVar PMID:11279519 PMID:11740341 PMID:12065767 PMID:12754175 PMID:15492926 NCBI chr 7:99,616,946...99,738,035
Ensembl chr 7:99,616,946...99,632,408 		JBrowse link
Grange Syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DAP3 death associated protein 3 IAGP ClinVar Annotator: match by term: Grange syndrome ClinVar PMID:25741868 NCBI chr 1:155,687,948...155,739,010
Ensembl chr 1:155,687,960...155,739,010 		JBrowse link
G YY1AP1 YY1 associated protein 1 IAGP
EXP		 ClinVar Annotator: match by term: Grange syndrome
ClinVar Annotator: match by term: GRANGE OCCLUSIVE ARTERIAL SYNDROME
CTD Direct Evidence: marker/mechanism		 ClinVar
CTD
OMIM		 PMID:11241488 PMID:25741868 PMID:27939641 PMID:30556293 NCBI chr 1:155,659,442...155,688,996
Ensembl chr 1:155,659,446...155,689,334 		JBrowse link
HELLP syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADAMTS13 ADAM metallopeptidase with thrombospondin type 1 motif 13 IEP protein:decreased activity:plasma (human) RGD PMID:12969811 RGD:10449045 NCBI chr 9:133,414,337...133,459,386
Ensembl chr 9:133,414,358...133,459,402 		JBrowse link
G AHSP alpha hemoglobin stabilizing protein IEP mRNA:decreased expression:placenta (human) RGD PMID:18347943 RGD:329956422 NCBI chr16:31,527,900...31,528,803
Ensembl chr16:31,527,900...31,528,803 		JBrowse link
G CD40LG CD40 ligand IEP protein:increased expression:blood platelet (human) RGD PMID:23241952 RGD:11522719 NCBI chr  X:136,648,158...136,660,390
Ensembl chr  X:136,648,158...136,660,390 		JBrowse link
G ERBB2 erb-b2 receptor tyrosine kinase 2 IEP RGD PMID:9158311 RGD:1580990 NCBI chr17:39,688,094...39,728,658
Ensembl chr17:39,687,914...39,730,426 		JBrowse link
G FAS Fas cell surface death receptor susceptibility IAGP
ISO		 DNA:SNP:promoter:-670A>G(rs1800682)(human)
protein,mRNA:altered expression:placenta, liver:		 RGD PMID:30066360 PMID:28501275 RGD:14700669, RGD:14700673 NCBI chr10:88,964,050...89,017,059
Ensembl chr10:88,953,813...89,029,605 		JBrowse link
G FASLG Fas ligand susceptibility IAGP
ISO		 DNA:SNP:intron:124A>G(rs5030772)(human)
protein:altered expression:blood, placenta, liver:		 RGD PMID:30066360 PMID:28501275 RGD:14700669, RGD:14700673 NCBI chr 1:172,659,103...172,666,876
Ensembl chr 1:172,659,103...172,666,876 		JBrowse link
HUPRA Syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC126805821 CDK7 strongly-dependent group 2 enhancer GRCh37_chr1:109779623-109780822 IAGP ClinVar Annotator: match by term: HYPERURICEMIA, PULMONARY HYPERTENSION, RENAL FAILURE, AND ALKALOSIS SYNDROME ClinVar PMID:25741868 PMID:28492532 NCBI chr 1:109,237,001...109,238,200 JBrowse link
G LOC130064387 ATAC-STARR-seq lymphoblastoid active region 14604 IAGP ClinVar Annotator: match by term: HYPERURICEMIA, PULMONARY HYPERTENSION, RENAL FAILURE, AND ALKALOSIS SYNDROME | ClinVar Annotator: match by term: Hyperuricemia, pulmonary hypertension, renal failure, and alkalosis ClinVar PMID:25741868 PMID:28492532 NCBI chr19:38,930,388...38,930,847 JBrowse link
G SARS1 seryl-tRNA synthetase 1 IAGP ClinVar Annotator: match by term: HYPERURICEMIA, PULMONARY HYPERTENSION, RENAL FAILURE, AND ALKALOSIS SYNDROME ClinVar PMID:25741868 PMID:28492532 NCBI chr 1:109,213,893...109,238,182
Ensembl chr 1:109,213,918...109,238,182 		JBrowse link
G SARS2 seryl-tRNA synthetase 2, mitochondrial IAGP ClinVar Annotator: match by term: Hyperuricemia, pulmonary hypertension, renal failure, and alkalosis
ClinVar Annotator: match by term: HYPERURICEMIA, PULMONARY HYPERTENSION, RENAL FAILURE, AND ALKALOSIS SYNDROME | ClinVar Annotator: match by term: Hyperuricemia, pulmonary hypertension, renal failure, and alkalosis
DNA:missense mutation:CDS:p.D390G (human)		 OMIM
ClinVar
RGD		 PMID:9536098 PMID:17576681 PMID:21255763 PMID:24034276 PMID:25741868 More... RGD:41410777 NCBI chr19:38,915,266...38,930,763
Ensembl chr19:38,915,266...38,930,763 		JBrowse link
hypertension and brachydactyly syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G LOC124625920 Sharpr-MPRA regulatory region 8059 IAGP ClinVar Annotator: match by term: Bilginturan syndrome ClinVar PMID:25741868 NCBI chr12:20,369,575...20,369,869 JBrowse link
G PDE3A phosphodiesterase 3A IAGP
EXP		 ClinVar Annotator: match by term: Bilginturan syndrome
CTD Direct Evidence: marker/mechanism		 OMIM
ClinVar
CTD		 PMID:4774535 PMID:25741868 PMID:25961942 PMID:28492532 PMID:29758562 More... NCBI chr12:20,368,537...20,688,583
Ensembl chr12:20,368,537...20,688,583 		JBrowse link
G PDE3A-AS1 PDE3A antisense RNA 1 IAGP ClinVar Annotator: match by term: Bilginturan syndrome ClinVar PMID:25741868 NCBI chr12:20,359,175...20,370,256
Ensembl chr12:20,361,484...20,370,262 		JBrowse link
Hypertension Resistant to Conventional Therapy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GSTM1 glutathione S-transferase mu 1 susceptibility IAGP DNA:deletion:cds: (human) RGD PMID:19279659 RGD:7495846 NCBI chr 1:109,687,817...109,693,745
Ensembl chr 1:109,687,814...109,709,039 		JBrowse link
G NOS3 nitric oxide synthase 3 IAGP ClinVar Annotator: match by term: Hypertension resistant to conventional therapy ClinVar PMID:9737779 PMID:9894802 PMID:10475066 PMID:10510054 PMID:10514107 More... NCBI chr 7:150,991,017...151,014,588
Ensembl chr 7:150,991,017...151,014,588 		JBrowse link
G PTPRD protein tyrosine phosphatase receptor type D susceptibility IAGP associated with coronary artery disease;DNA:SNP:intron: (rs324498) (human) RGD PMID:30237584 RGD:401976431 NCBI chr 9:8,314,246...10,613,002
Ensembl chr 9:8,314,246...10,613,002 		JBrowse link
Hypertension, Early-Onset, Autosomal Dominant, with Severe Exacerbation in Pregnancy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NR3C2 nuclear receptor subfamily 3 group C member 2 IAGP
EXP		 ClinVar Annotator: match by term: Hypertension, early-onset, autosomal dominant, with exacerbation in pregnancy
ClinVar Annotator: match by term: Hypertension, early-onset, autosomal dominant, with severe exacerbation in pregnancy
CTD Direct Evidence: marker/mechanism		 ClinVar
CTD
OMIM		 PMID:10884226 PMID:15126534 PMID:16757525 PMID:22463955 PMID:25741868 More... NCBI chr 4:148,078,764...148,445,508
Ensembl chr 4:148,078,762...148,444,698 		JBrowse link
Hypertensive Nephropathy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGT angiotensinogen treatment ISO RGD PMID:22089474 RGD:8548895 NCBI chr 1:230,702,523...230,745,583
Ensembl chr 1:230,690,776...230,745,576 		JBrowse link
G AGTR1 angiotensin II receptor type 1 treatment ISO RGD PMID:22089474 RGD:8548895 NCBI chr 3:148,697,903...148,743,003
Ensembl chr 3:148,697,784...148,743,008 		JBrowse link
G CFL1 cofilin 1 ISO protein:increased phosphorylation:kidney (rat) RGD PMID:26450610 RGD:11520804 NCBI chr11:65,854,673...65,858,180
Ensembl chr11:65,823,022...65,862,026 		JBrowse link
G COL1A1 collagen type I alpha 1 chain ISO mRNA:increased expression:juxtamedullary cortex (rat) RGD PMID:17977875 RGD:2290351 NCBI chr17:50,184,101...50,201,631
Ensembl chr17:50,184,101...50,201,632 		JBrowse link
G HP haptoglobin treatment ISO RGD PMID:24029866 RGD:11041817 NCBI chr16:72,054,505...72,061,055
Ensembl chr16:72,054,505...72,061,055 		JBrowse link
G MMP2 matrix metallopeptidase 2 ameliorates ISO RGD PMID:37643020 RGD:401827835 NCBI chr16:55,478,830...55,506,691
Ensembl chr16:55,389,700...55,506,691 		JBrowse link
G NPPB natriuretic peptide B ISO RGD PMID:26063669 RGD:12910116 NCBI chr 1:11,857,464...11,858,945
Ensembl chr 1:11,857,464...11,858,945 		JBrowse link
G POSTN periostin disease_progression ISO mRNA,protein:increased expression:kidney: RGD PMID:22403621 RGD:10041032 NCBI chr13:37,562,585...37,598,768
Ensembl chr13:37,562,583...37,598,844 		JBrowse link
G PPARA peroxisome proliferator activated receptor alpha ISO RGD PMID:20671072 RGD:5509943 NCBI chr22:46,150,526...46,243,756
Ensembl chr22:46,150,521...46,243,755 		JBrowse link
G RAG1 recombination activating 1 ameliorates ISO RGD PMID:23364523 PMID:23364523 RGD:7207429, RGD:7207429 NCBI chr11:36,510,353...36,579,762
Ensembl chr11:36,510,372...36,593,156 		JBrowse link
G SHC1 SHC adaptor protein 1 ISO protein:increased expression:kidney RGD PMID:27270176 RGD:12792230 NCBI chr 1:154,962,298...154,974,376
Ensembl chr 1:154,962,298...154,974,395 		JBrowse link
G SIRT6 sirtuin 6 IEP protein:decreased expression:kidney RGD PMID:30894089 RGD:155260334 NCBI chr19:4,174,109...4,182,563
Ensembl chr19:4,174,109...4,182,566 		JBrowse link
Hypertensive Nephrosclerosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACE angiotensin I converting enzyme treatment
severity		 ISO
IEP		 protein:increased expression:nephron tubule, kidney interstitium (human) RGD PMID:10580398 PMID:21346373 RGD:12879397, RGD:40818408 NCBI chr17:63,477,061...63,498,373
Ensembl chr17:63,477,061...63,498,380 		JBrowse link
G ACE2 angiotensin converting enzyme 2 severity IEP mRNA, protein:decreased expression, increased expression:nephron tubule, kidney interstitium (human) RGD PMID:21346373 RGD:40818408 NCBI chr  X:15,518,197...15,607,211
Ensembl chr  X:15,494,566...15,607,236 		JBrowse link
G MIR214 microRNA 214 IEP RNA:increased expression:kidney RGD PMID:30049682 RGD:38500245 NCBI chr 1:172,138,798...172,138,907
Ensembl chr 1:172,138,798...172,138,907 		JBrowse link
hypertensive retinopathy term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CRP C-reactive protein IEP protein:increased expression:blood: RGD PMID:21091359 RGD:9491786 NCBI chr 1:159,712,289...159,714,589
Ensembl chr 1:159,712,289...159,714,589 		JBrowse link
G SOX17 SRY-box transcription factor 17 treatment ISO RGD PMID:36200131 RGD:329853320 NCBI chr 8:54,457,935...54,460,892
Ensembl chr 8:54,457,935...54,460,892 		JBrowse link
Hypomagnesemia, Hypertension, and Hypercholesterolemia, Mitochondrial term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G MT-TI mitochondrially encoded tRNA-Ile (AUU/C) IAGP ClinVar Annotator: match by term: Hypomagnesemia, hypertension, and hypercholesterolemia, mitochondrial ClinVar PMID:15498972 PMID:34607911 NCBI chr MT:4,263...4,331
Ensembl chr MT:4,263...4,331 		JBrowse link
Isolated Systolic Hypertension term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G APOB apolipoprotein B IAGP ClinVar Annotator: match by term: Isolated systolic hypertension ClinVar PMID:25741868 PMID:28492532 NCBI chr 2:21,001,429...21,044,073
Ensembl chr 2:21,001,429...21,044,073 		JBrowse link
G BSCL2 BSCL2 lipid droplet biogenesis associated, seipin IAGP ClinVar Annotator: match by term: Isolated systolic hypertension ClinVar PMID:25741868 PMID:28492532 NCBI chr11:62,690,262...62,709,537
Ensembl chr11:62,689,289...62,709,845 		JBrowse link
G HNRNPUL2-BSCL2 HNRNPUL2-BSCL2 readthrough (NMD candidate) IAGP ClinVar Annotator: match by term: Isolated systolic hypertension ClinVar PMID:25741868 PMID:28492532 NCBI chr11:62,690,262...62,727,384
Ensembl chr11:62,690,275...62,727,384 		JBrowse link
malignant hypertension term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADM adrenomedullin IEP protein:increased expression:plasma RGD PMID:15284680 RGD:1625303 NCBI chr11:10,305,073...10,307,397
Ensembl chr11:10,305,073...10,307,397 		JBrowse link
G AGT angiotensinogen EXP CTD Direct Evidence: marker/mechanism CTD PMID:2493837 PMID:27428043 NCBI chr 1:230,702,523...230,745,583
Ensembl chr 1:230,690,776...230,745,576 		JBrowse link
G CYP17A1 cytochrome P450 family 17 subfamily A member 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:3142437 NCBI chr10:102,830,531...102,837,413
Ensembl chr10:102,830,531...102,837,472 		JBrowse link
G REN renin EXP CTD Direct Evidence: marker/mechanism CTD PMID:2493837 NCBI chr 1:204,154,819...204,166,337
Ensembl chr 1:204,154,819...204,190,324 		JBrowse link
Masked Hypertension term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ADIPOQ adiponectin, C1Q and collagen domain containing IEP protein:decreased expression:plasma RGD PMID:19222669 RGD:5686820 NCBI chr 3:186,842,710...186,858,463
Ensembl chr 3:186,842,704...186,858,463 		JBrowse link
mild pre-eclampsia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G GPX3 glutathione peroxidase 3 IEP protein:increased expression:plasma RGD PMID:8476834 RGD:401827852 NCBI chr 5:151,020,591...151,028,988
Ensembl chr 5:151,020,591...151,028,988 		JBrowse link
Neonatal Pulmonary Hypertension term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CPS1 carbamoyl-phosphate synthase 1 susceptibility IAGP ClinVar Annotator: match by term: Pulmonary hypertension, neonatal, susceptibility to ClinVar
OMIM		 PMID:8486760 PMID:9536098 PMID:9686343 PMID:9711878 PMID:11388595 More... NCBI chr 2:210,477,685...210,679,107
Ensembl chr 2:210,477,682...210,679,107 		JBrowse link
nephrosclerosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACTA2 actin alpha 2, smooth muscle EXP CTD Direct Evidence: marker/mechanism CTD PMID:30818366 NCBI chr10:88,935,074...88,991,337
Ensembl chr10:88,934,822...88,991,339 		JBrowse link
G ADRB1 adrenoceptor beta 1 disease_progression IAGP associated with hypertension;DNA:missense mutations, haplotype:cds:p.S49G(rs1801252),p.R389G (rs1801253)(human): RGD PMID:19745105 RGD:7241815 NCBI chr10:114,043,866...114,046,904
Ensembl chr10:114,043,866...114,046,904 		JBrowse link
G ALOX5 arachidonate 5-lipoxygenase EXP CTD Direct Evidence: marker/mechanism CTD PMID:30818366 NCBI chr10:45,374,216...45,446,117
Ensembl chr10:45,374,176...45,446,119 		JBrowse link
G ALPK1 alpha kinase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:27542954 NCBI chr 4:112,297,369...112,442,621
Ensembl chr 4:112,285,509...112,442,621 		JBrowse link
G COL1A1 collagen type I alpha 1 chain EXP CTD Direct Evidence: marker/mechanism CTD PMID:30818366 NCBI chr17:50,184,101...50,201,631
Ensembl chr17:50,184,101...50,201,632 		JBrowse link
G COL3A1 collagen type III alpha 1 chain EXP CTD Direct Evidence: marker/mechanism CTD PMID:30818366 NCBI chr 2:188,974,373...189,012,746
Ensembl chr 2:188,974,373...189,012,746 		JBrowse link
G CXCL12 C-X-C motif chemokine ligand 12 EXP CTD Direct Evidence: marker/mechanism CTD PMID:30818366 NCBI chr10:44,370,165...44,385,097
Ensembl chr10:44,370,165...44,386,493 		JBrowse link
G CXCR4 C-X-C motif chemokine receptor 4 EXP CTD Direct Evidence: marker/mechanism CTD PMID:30818366 NCBI chr 2:136,114,349...136,118,149
Ensembl chr 2:136,114,349...136,119,177 		JBrowse link
G FGF2 fibroblast growth factor 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:30818366 NCBI chr 4:122,826,682...122,898,236
Ensembl chr 4:122,826,682...122,898,236 		JBrowse link
G HIPK2 homeodomain interacting protein kinase 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28318631 NCBI chr 7:139,561,570...139,777,998
Ensembl chr 7:139,561,570...139,777,998 		JBrowse link
G LTB4R leukotriene B4 receptor ISO CTD Direct Evidence: marker/mechanism CTD PMID:30818366 NCBI chr14:24,311,502...24,318,036
Ensembl chr14:24,311,450...24,318,036 		JBrowse link
G MTHFR methylenetetrahydrofolate reductase IAGP DNA:transition, transversion:cds:g.677C>T, g.1298A>C (human) RGD PMID:21613384 RGD:6893469 NCBI chr 1:11,785,723...11,805,964
Ensembl chr 1:11,785,723...11,806,455 		JBrowse link
G PTGDS prostaglandin D2 synthase IEP associated with Hypertension;protein:increased expression:serum, urine RGD PMID:11882588 RGD:1642584 NCBI chr 9:136,977,504...136,981,742
Ensembl chr 9:136,975,092...136,981,742 		JBrowse link
G S100A4 S100 calcium binding protein A4 EXP CTD Direct Evidence: marker/mechanism CTD PMID:30818366 NCBI chr 1:153,543,621...153,545,806
Ensembl chr 1:153,543,613...153,550,136 		JBrowse link
G TGFB1 transforming growth factor beta 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:30818366 NCBI chr19:41,330,323...41,353,922
Ensembl chr19:41,301,587...41,353,922 		JBrowse link
persistent fetal circulation syndrome term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AC009123.1 novel transcript, antisense to ADAD2 IAGP ClinVar Annotator: match by term: Congenital alveolar capillary dysplasia ClinVar NCBI chr16:84,192,558...84,197,053
Ensembl chr16:84,192,558...84,197,053 		JBrowse link
G ADAD2 adenosine deaminase domain containing 2 IAGP ClinVar Annotator: match by term: Congenital alveolar capillary dysplasia ClinVar NCBI chr16:84,191,157...84,197,166
Ensembl chr16:84,191,138...84,197,168 		JBrowse link
G ATP2C2 ATPase secretory pathway Ca2+ transporting 2 IAGP ClinVar Annotator: match by term: Congenital alveolar capillary dysplasia ClinVar NCBI chr16:84,368,538...84,464,187
Ensembl chr16:84,368,527...84,464,187 		JBrowse link
G C16orf74 chromosome 16 open reading frame 74 IAGP ClinVar Annotator: match by term: Congenital alveolar capillary dysplasia ClinVar NCBI chr16:85,707,517...85,751,096
Ensembl chr16:85,690,084...85,751,129 		JBrowse link
G C16orf95 chromosome 16 open reading frame 95 IAGP ClinVar Annotator: match by term: Congenital alveolar capillary dysplasia ClinVar NCBI chr16:87,302,814...87,317,392
Ensembl chr16:87,083,562...87,317,420 		JBrowse link
G CIBAR2 CBY1 interacting BAR domain containing 2 IAGP ClinVar Annotator: match by term: Congenital alveolar capillary dysplasia ClinVar NCBI chr16:85,098,358...85,112,472
Ensembl chr16:85,098,358...85,112,472 		JBrowse link
G COTL1 coactosin like F-actin binding protein 1 IAGP ClinVar Annotator: match by term: Congenital alveolar capillary dysplasia ClinVar NCBI chr16:84,565,596...84,618,078
Ensembl chr16:84,565,596...84,618,078 		JBrowse link
G COX4I1 cytochrome c oxidase subunit 4I1 IAGP ClinVar Annotator: match by term: Congenital alveolar capillary dysplasia ClinVar NCBI chr16:85,799,695...85,807,068
Ensembl chr16:85,798,633...85,807,068 		JBrowse link
G CPS1 carbamoyl-phosphate synthase 1 IAGP
EXP		 CACD, OMIM:265380, DNA:polymorphism:T1405N
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:11407344 PMID:11407344 RGD:1600716 NCBI chr 2:210,477,685...210,679,107
Ensembl chr 2:210,477,682...210,679,107 		JBrowse link
G CRISPLD2 cysteine rich secretory protein LCCL domain containing 2 IAGP ClinVar Annotator: match by term: Congenital alveolar capillary dysplasia ClinVar NCBI chr16:84,819,985...84,909,508
Ensembl chr16:84,819,985...84,920,768 		JBrowse link
G DNAAF1 dynein axonemal assembly factor 1 IAGP ClinVar Annotator: match by term: Congenital alveolar capillary dysplasia ClinVar NCBI chr16:84,145,308...84,177,920
Ensembl chr16:84,145,287...84,178,767 		JBrowse link
G EMC8 ER membrane protein complex subunit 8 IAGP ClinVar Annotator: match by term: Congenital alveolar capillary dysplasia ClinVar NCBI chr16:85,778,624...85,799,544
Ensembl chr16:85,771,758...85,799,608 		JBrowse link
G FBXO31 F-box protein 31 IAGP ClinVar Annotator: match by term: Congenital alveolar capillary dysplasia ClinVar NCBI chr16:87,326,987...87,392,121
Ensembl chr16:87,326,987...87,392,142 		JBrowse link
G FENDRR FOXF1 adjacent non-coding developmental regulatory RNA IAGP ClinVar Annotator: match by term: Congenital alveolar capillary dysplasia ClinVar PMID:25741868 NCBI chr16:86,474,525...86,508,860
Ensembl chr16:86,474,525...86,509,099 		JBrowse link
G FOXC2 forkhead box C2 IAGP ClinVar Annotator: match by term: Congenital alveolar capillary dysplasia ClinVar NCBI chr16:86,566,829...86,569,728
Ensembl chr16:86,566,829...86,569,728 		JBrowse link
G FOXF1 forkhead box F1 IAGP
ISS
EXP		 ClinVar Annotator: match by term: Congenital alveolar capillary dysplasia
ClinVar Annotator: match by term: ALVEOLAR CAPILLARY DYSPLASIA WITH MISALIGNMENT OF PULMONARY VEINS AND OTHER CONGENITAL ANOMALIES | ClinVar Annotator: match by term: Alveolar capillary dysplasia with misalignment of pulmonary veins | ClinVar Annotator: match by term: Congenital alveolar capillary dysplasia
OMIM:265380
CTD Direct Evidence: marker/mechanism		 ClinVar
MouseDO
CTD
OMIM		 PMID:15520767 PMID:19500772 PMID:23505205 PMID:24033266 PMID:25741868 More... NCBI chr16:86,510,527...86,515,422
Ensembl chr16:86,510,527...86,515,422 		JBrowse link
G FOXL1 forkhead box L1 IAGP ClinVar Annotator: match by term: Congenital alveolar capillary dysplasia ClinVar NCBI chr16:86,578,549...86,583,478
Ensembl chr16:86,576,368...86,583,478 		JBrowse link
G GINS2 GINS complex subunit 2 IAGP ClinVar Annotator: match by term: Congenital alveolar capillary dysplasia ClinVar NCBI chr16:85,676,198...85,688,954
Ensembl chr16:85,676,198...85,690,073 		JBrowse link
G GSE1 Gse1 coiled-coil protein IAGP ClinVar Annotator: match by term: Congenital alveolar capillary dysplasia ClinVar NCBI chr16:85,169,512...85,676,200
Ensembl chr16:85,169,525...85,676,204 		JBrowse link
G HSDL1 hydroxysteroid dehydrogenase like 1 IAGP ClinVar Annotator: match by term: Congenital alveolar capillary dysplasia ClinVar NCBI chr16:84,122,141...84,145,177
Ensembl chr16:84,122,141...84,145,192 		JBrowse link
G IRF8 interferon regulatory factor 8 IAGP ClinVar Annotator: match by term: Congenital alveolar capillary dysplasia ClinVar NCBI chr16:85,899,162...85,922,609
Ensembl chr16:85,899,116...85,922,606 		JBrowse link
G ITGAM integrin subunit alpha M IAGP DNA:missense mutation:CDS:p.E1071D (human) RGD PMID:32054482 RGD:329853760 NCBI chr16:31,259,975...31,332,877
Ensembl chr16:31,259,967...31,332,892 		JBrowse link
G JPH3 junctophilin 3 IAGP ClinVar Annotator: match by term: Congenital alveolar capillary dysplasia ClinVar NCBI chr16:87,601,835...87,698,156
Ensembl chr16:87,601,835...87,698,156 		JBrowse link
G KCNG4 potassium voltage-gated channel modifier subfamily G member 4 IAGP ClinVar Annotator: match by term: Congenital alveolar capillary dysplasia ClinVar NCBI chr16:84,218,657...84,240,012
Ensembl chr16:84,218,657...84,240,012 		JBrowse link
G KIAA0513 KIAA0513 IAGP ClinVar Annotator: match by term: Congenital alveolar capillary dysplasia ClinVar NCBI chr16:85,027,795...85,094,230
Ensembl chr16:85,027,782...85,094,230 		JBrowse link
G KLHL36 kelch like family member 36 IAGP ClinVar Annotator: match by term: Congenital alveolar capillary dysplasia ClinVar NCBI chr16:84,648,511...84,667,686
Ensembl chr16:84,648,511...84,667,686 		JBrowse link
G LINC01082 long intergenic non-protein coding RNA 1082 IAGP ClinVar Annotator: match by term: Congenital alveolar capillary dysplasia ClinVar NCBI chr16:86,196,181...86,199,720
Ensembl chr16:86,151,351...86,244,348 		JBrowse link
G MAP1LC3B microtubule associated protein 1 light chain 3 beta IAGP ClinVar Annotator: match by term: Congenital alveolar capillary dysplasia ClinVar NCBI chr16:87,392,336...87,404,774
Ensembl chr16:87,383,953...87,404,779 		JBrowse link
G MBTPS1 membrane bound transcription factor peptidase, site 1 IAGP ClinVar Annotator: match by term: Congenital alveolar capillary dysplasia ClinVar NCBI chr16:84,053,763...84,116,942
Ensembl chr16:84,053,761...84,116,942 		JBrowse link
G MEAK7 MTOR associated protein, eak-7 homolog IAGP ClinVar Annotator: match by term: Congenital alveolar capillary dysplasia ClinVar NCBI chr16:84,476,355...84,504,659
Ensembl chr16:84,476,355...84,554,033 		JBrowse link
G MLYCD malonyl-CoA decarboxylase IAGP ClinVar Annotator: match by term: Congenital alveolar capillary dysplasia ClinVar NCBI chr16:83,899,115...83,927,031
Ensembl chr16:83,899,115...83,951,445 		JBrowse link
G MTHFSD methenyltetrahydrofolate synthetase domain containing IAGP ClinVar Annotator: match by term: Congenital alveolar capillary dysplasia ClinVar NCBI chr16:86,530,186...86,555,235
Ensembl chr16:86,530,178...86,555,235 		JBrowse link
G NECAB2 N-terminal EF-hand calcium binding protein 2 IAGP ClinVar Annotator: match by term: Congenital alveolar capillary dysplasia ClinVar NCBI chr16:83,965,177...84,002,776
Ensembl chr16:83,968,244...84,002,776 		JBrowse link
G NOS3 nitric oxide synthase 3 ISS OMIM:265380 MouseDO NCBI chr 7:150,991,017...151,014,588
Ensembl chr 7:150,991,017...151,014,588 		JBrowse link
G OSGIN1 oxidative stress induced growth inhibitor 1 IAGP ClinVar Annotator: match by term: Congenital alveolar capillary dysplasia ClinVar NCBI chr16:83,953,240...83,966,332
Ensembl chr16:83,931,311...83,966,332 		JBrowse link
G PTEN phosphatase and tensin homolog ISS OMIM:265380 MouseDO NCBI chr10:87,863,625...87,971,930
Ensembl chr10:87,862,638...87,971,930 		JBrowse link
G SLC38A8 solute carrier family 38 member 8 IAGP ClinVar Annotator: match by term: Congenital alveolar capillary dysplasia ClinVar NCBI chr16:84,009,667...84,043,372
Ensembl chr16:84,009,667...84,042,795 		JBrowse link
G STRA6 signaling receptor and transporter of retinol STRA6 EXP CTD Direct Evidence: marker/mechanism CTD PMID:17273977 NCBI chr15:74,179,466...74,212,259
Ensembl chr15:74,179,466...74,212,267 		JBrowse link
G TAF1C TATA-box binding protein associated factor, RNA polymerase I subunit C IAGP ClinVar Annotator: match by term: Congenital alveolar capillary dysplasia ClinVar NCBI chr16:84,177,855...84,187,057
Ensembl chr16:84,177,847...84,187,070 		JBrowse link
G USP10 ubiquitin specific peptidase 10 IAGP ClinVar Annotator: match by term: Congenital alveolar capillary dysplasia ClinVar NCBI chr16:84,700,000...84,779,922
Ensembl chr16:84,699,986...84,779,922 		JBrowse link
G WFDC1 WAP four-disulfide core domain 1 IAGP ClinVar Annotator: match by term: Congenital alveolar capillary dysplasia ClinVar NCBI chr16:84,294,878...84,329,844
Ensembl chr16:84,294,846...84,329,844 		JBrowse link
G ZCCHC14 zinc finger CCHC-type containing 14 IAGP ClinVar Annotator: match by term: Congenital alveolar capillary dysplasia ClinVar NCBI chr16:87,406,248...87,493,024
Ensembl chr16:87,406,246...87,493,024 		JBrowse link
G ZCCHC14-DT ZCCHC14 divergent transcript IAGP ClinVar Annotator: match by term: Congenital alveolar capillary dysplasia ClinVar NCBI chr16:87,494,187...87,515,630
Ensembl chr16:87,492,555...87,516,940 		JBrowse link
G ZDHHC7 zinc finger DHHC-type palmitoyltransferase 7 IAGP ClinVar Annotator: match by term: Congenital alveolar capillary dysplasia ClinVar NCBI chr16:84,974,175...85,027,631
Ensembl chr16:84,974,175...85,011,535 		JBrowse link
pre-eclampsia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACE angiotensin I converting enzyme onset EXP
IAGP		 CTD Direct Evidence: marker/mechanism
DNA:insertion/deletion:intron 16:		 CTD
RGD		 PMID:17114810 PMID:20044877 RGD:40400703 NCBI chr17:63,477,061...63,498,373
Ensembl chr17:63,477,061...63,498,380 		JBrowse link
G ACVR2B activin A receptor type 2B IEP protein:increased expression:placenta (human) RGD PMID:27176145 RGD:329853749 NCBI chr 3:38,453,890...38,493,142
Ensembl chr 3:38,453,890...38,493,142 		JBrowse link
G ADD1 adducin 1 IEP mRNA:increased expression:blood RGD PMID:19731222 RGD:5147993 NCBI chr 4:2,843,844...2,930,062
Ensembl chr 4:2,843,844...2,930,076 		JBrowse link
G AGT angiotensinogen IAGP
EXP
IMP		 DNA:polymorphism: :p.M235T (human)
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:8513325 PMID:8513325 PMID:20530295 RGD:1300394, RGD:13432363 NCBI chr 1:230,702,523...230,745,583
Ensembl chr 1:230,690,776...230,745,576 		JBrowse link
G AKR1C3 aldo-keto reductase family 1 member C3 treatment IEP
ISO		 mRNA:decreased expression:blood: RGD PMID:19681734 PMID:25876805 RGD:10053633, RGD:11541124 NCBI chr10:5,048,781...5,107,686
Ensembl chr10:5,035,354...5,107,686 		JBrowse link
G ALB albumin severity IEP RGD PMID:21923989 RGD:11035264 NCBI chr 4:73,404,287...73,421,482
Ensembl chr 4:73,397,114...73,421,482 		JBrowse link
G ALKBH5 alkB homolog 5, RNA demethylase EXP CTD Direct Evidence: marker/mechanism CTD PMID:34995009 NCBI chr17:18,183,828...18,209,954
Ensembl chr17:18,183,078...18,209,954 		JBrowse link
G ANXA5 annexin A5 EXP CTD Direct Evidence: therapeutic CTD PMID:19837457 NCBI chr 4:121,667,946...121,696,980
Ensembl chr 4:121,667,946...121,696,995 		JBrowse link
G APELA apelin receptor early endogenous ligand ISS OMIM:189800 | OMIM:609402 | OMIM:609403 | OMIM:609404 | OMIM:614592 MouseDO NCBI chr 4:164,877,178...164,899,007
Ensembl chr 4:164,877,178...164,898,965 		JBrowse link
G ARHGAP45 Rho GTPase activating protein 45 EXP CTD Direct Evidence: marker/mechanism CTD PMID:26095815 NCBI chr19:1,065,959...1,086,628
Ensembl chr19:1,065,923...1,086,628 		JBrowse link
G ARID1A AT-rich interaction domain 1A disease_progression IEP associated with Fetal Growth Retardation; protein:increased expression:placenta, nucleus (human) RGD PMID:32529396 RGD:243065143 NCBI chr 1:26,696,015...26,782,104
Ensembl chr 1:26,693,236...26,782,104 		JBrowse link
G ASB4 ankyrin repeat and SOCS box containing 4 ISS OMIM:189800 | OMIM:609402 | OMIM:609403 | OMIM:609404 | OMIM:614592 MouseDO NCBI chr 7:95,470,656...95,551,317
Ensembl chr 7:95,478,444...95,540,233 		JBrowse link
G ATP2B1 ATPase plasma membrane Ca2+ transporting 1 IEP mRNA:decreased expression:placenta (human) RGD PMID:36477942 RGD:401901174 NCBI chr12:89,588,049...89,709,366
Ensembl chr12:89,588,049...89,709,366 		JBrowse link
G ATP2B2 ATPase plasma membrane Ca2+ transporting 2 IEP mRNA:decreased expression:placenta (human) RGD PMID:36477942 RGD:401901174 NCBI chr 3:10,324,023...10,708,007
Ensembl chr 3:10,324,023...10,708,007 		JBrowse link
G ATP2B3 ATPase plasma membrane Ca2+ transporting 3 IEP mRNA:decreased expression:placenta (human) RGD PMID:36477942 RGD:401901174 NCBI chr  X:153,517,642...153,582,929
Ensembl chr  X:153,517,642...153,582,939 		JBrowse link
G ATP2B4 ATPase plasma membrane Ca2+ transporting 4 IEP mRNA:decreased expression:placenta (human) RGD PMID:36477942 RGD:401901174 NCBI chr 1:203,626,832...203,744,081
Ensembl chr 1:203,626,832...203,744,081 		JBrowse link
G BNIP3P1 BCL2 interacting protein 3 pseudogene 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:35187800 NCBI chr14:28,264,410...28,265,974
Ensembl chr14:28,264,554...28,265,133 		JBrowse link
G C3 complement C3 treatment ISO RGD PMID:23685261 RGD:7411624 NCBI chr19:6,677,704...6,720,650
Ensembl chr19:6,677,704...6,730,562 		JBrowse link
G CALB1 calbindin 1 IEP mRNA:decreased expression:placenta (human) RGD PMID:36477942 RGD:401901174 NCBI chr 8:90,058,608...90,082,879
Ensembl chr 8:90,058,608...90,095,475 		JBrowse link
G CCL5 C-C motif chemokine ligand 5 ISO protein:increased secretion:serum (rat) RGD PMID:19617880 RGD:2317272 NCBI chr17:35,871,491...35,880,360
Ensembl chr17:35,871,491...35,880,793 		JBrowse link
G CCN3 cellular communication network factor 3 IEP protein:decreased expression:placenta (human) RGD PMID:16675545 RGD:1580971 NCBI chr 8:119,416,446...119,424,434
Ensembl chr 8:119,416,446...119,424,434 		JBrowse link
G CD274 CD274 molecule treatment ISO RGD PMID:27277012 RGD:40886269 NCBI chr 9:5,450,542...5,470,554
Ensembl chr 9:5,450,503...5,470,566 		JBrowse link
G CD40 CD40 molecule IEP protein:increased expression:blood, monocyte (human) RGD PMID:19221099 RGD:11520792 NCBI chr20:46,118,314...46,129,858
Ensembl chr20:46,118,271...46,129,863 		JBrowse link
G CD40LG CD40 ligand treatment ISO
IEP		 protein:increased expression:blood platelet (human) RGD PMID:26310940 PMID:23241952 RGD:11056772, RGD:11522719 NCBI chr  X:136,648,158...136,660,390
Ensembl chr  X:136,648,158...136,660,390 		JBrowse link
G CD46 CD46 molecule susceptibility
no_association		 IAGP DNA:missense mutation:cds:p.A304V (human) RGD PMID:21445332 PMID:25710174 RGD:6483459, RGD:11352807 NCBI chr 1:207,752,038...207,795,516
Ensembl chr 1:207,752,037...207,795,513 		JBrowse link
G CDKN1C cyclin dependent kinase inhibitor 1C ISS OMIM:189800 | OMIM:609402 | OMIM:609403 | OMIM:609404 | OMIM:614592 MouseDO NCBI chr11:2,883,218...2,885,775
Ensembl chr11:2,883,213...2,885,775 		JBrowse link
G CEBPA CCAAT enhancer binding protein alpha EXP CTD Direct Evidence: marker/mechanism CTD PMID:34398343 NCBI chr19:33,299,934...33,302,534
Ensembl chr19:33,299,934...33,302,534 		JBrowse link
G CHI3L1 chitinase 3 like 1 IEP protein:increased secretion:umbilical cord, serum (human) RGD PMID:18054022 RGD:4892664 NCBI chr 1:203,178,931...203,186,704
Ensembl chr 1:203,178,931...203,186,704 		JBrowse link
G CLU clusterin IAGP DNA:SNP:exon:866C>T (human) RGD PMID:15925890 RGD:1581195 NCBI chr 8:27,596,917...27,614,700
Ensembl chr 8:27,596,917...27,614,700 		JBrowse link
G CMKLR1 chemerin chemokine-like receptor 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:34398343 NCBI chr12:108,288,046...108,339,311
Ensembl chr12:108,288,044...108,339,317 		JBrowse link
G COMT catechol-O-methyltransferase ISS OMIM:189800 | OMIM:609402 | OMIM:609403 | OMIM:609404 | OMIM:614592 MouseDO NCBI chr22:19,941,772...19,969,975
Ensembl chr22:19,941,371...19,969,975 		JBrowse link
G CORIN corin, serine peptidase EXP CTD Direct Evidence: marker/mechanism CTD NCBI chr 4:47,594,001...47,838,067
Ensembl chr 4:47,593,999...47,838,106 		JBrowse link
G CP ceruloplasmin EXP CTD Direct Evidence: marker/mechanism CTD PMID:18679377 NCBI chr 3:149,162,414...149,221,829
Ensembl chr 3:149,162,410...149,221,829 		JBrowse link
G CREBBP CREB binding protein IEP mRNA:decreased expression:placenta (human) RGD PMID:33625689 RGD:153350159 NCBI chr16:3,725,054...3,880,713
Ensembl chr16:3,725,054...3,880,713 		JBrowse link
G CST3 cystatin C IEP protein:increased expression:plasma (human) RGD PMID:18197549 RGD:2314350 NCBI chr20:23,626,706...23,637,955
Ensembl chr20:23,626,706...23,638,473 		JBrowse link
G CUBN cubilin IEP associated with late term delivery; mRNA:decreased expression:placenta (human) RGD PMID:32682061 RGD:401901078 NCBI chr10:16,823,966...17,129,811
Ensembl chr10:16,823,966...17,129,811 		JBrowse link
G CYP11B2 cytochrome P450 family 11 subfamily B member 2 IAGP DNA:missense mutation:cds:p.V386A (human) RGD PMID:15569322 RGD:1576428 NCBI chr 8:142,910,559...142,917,843
Ensembl chr 8:142,910,559...142,917,843 		JBrowse link
G CYP24A1 cytochrome P450 family 24 subfamily A member 1 IEP associated with hypoxia; protein:increased expression:placenta (human)
mRNA:increased expression:placenta (human)		 RGD PMID:22871339 PMID:36477942 RGD:401901075, RGD:401901174 NCBI chr20:54,143,538...54,173,986
Ensembl chr20:54,153,446...54,173,986 		JBrowse link
G CYP27B1 cytochrome P450 family 27 subfamily B member 1 IEP associated with hypoxia; protein:increased expression:placenta (human)
mRNA:increased expression:placenta (human)		 RGD PMID:22871339 PMID:36477942 RGD:401901075, RGD:401901174 NCBI chr12:57,762,334...57,767,078
Ensembl chr12:57,762,334...57,768,986 		JBrowse link
G CYP2J2 cytochrome P450 family 2 subfamily J member 2 IEP
ISO		 mRNA:increased expression:placenta, decidua RGD PMID:23155181 PMID:23155181 RGD:7243127, RGD:7243127 NCBI chr 1:59,893,308...59,969,212
Ensembl chr 1:59,893,308...59,926,773 		JBrowse link
G CYP2R1 cytochrome P450 family 2 subfamily R member 1 IEP associated with hypoxia; protein:decreased expression:placenta (human)
mRNA:decreased expression:placenta (human)		 RGD PMID:22871339 PMID:36477942 PMID:32682061 RGD:401901075, RGD:401901174, RGD:401901078 NCBI chr11:14,877,440...14,892,443
Ensembl chr11:14,877,440...14,892,231 		JBrowse link
G DAB2IP DAB2 interacting protein IEP mRNA, protein:decreased expression:placenta (human) RGD PMID:25604087 RGD:11553571 NCBI chr 9:121,567,074...121,785,530
Ensembl chr 9:121,567,057...121,785,530 		JBrowse link
G DDAH2 DDAH family member 2, ADMA-independent EXP CTD Direct Evidence: marker/mechanism CTD PMID:22285683 NCBI chr 6:31,727,040...31,730,263
Ensembl chr 6:31,727,038...31,730,617 		JBrowse link
G DNAH8 dynein axonemal heavy chain 8 IEP mRNA:decreased expression:placenta (human) RGD PMID:36477942 RGD:401901174 NCBI chr 6:38,715,311...39,030,792
Ensembl chr 6:38,715,311...39,030,792 		JBrowse link
G EBAG9 estrogen receptor binding site associated antigen 9 IEP protein:increased expression:decidua RGD PMID:17845206 RGD:2289846 NCBI chr 8:109,539,702...109,565,996
Ensembl chr 8:109,539,711...109,570,072 		JBrowse link
G EBI3 Epstein-Barr virus induced 3 ameliorates ISO RGD PMID:31203154 RGD:213230155 NCBI chr19:4,229,523...4,237,528
Ensembl chr19:4,229,523...4,237,528 		JBrowse link
G EDN1 endothelin 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:25230003 NCBI chr 6:12,230,516...12,297,194
Ensembl chr 6:12,290,361...12,297,194 		JBrowse link
G EDN2 endothelin 2 IEP RGD PMID:9015697 RGD:1580919 NCBI chr 1:41,478,775...41,484,683
Ensembl chr 1:41,478,775...41,484,683 		JBrowse link
G EIF3D eukaryotic translation initiation factor 3 subunit D EXP CTD Direct Evidence: marker/mechanism CTD PMID:34520790 NCBI chr22:36,510,855...36,529,166
Ensembl chr22:36,510,855...36,529,184 		JBrowse link
G ENG endoglin severity
treatment		 IEP
ISO		 protein:increased expression:serum (human)
protein:increased expression:serum (rat)
protein:increased expression:plasma (mouse)		 RGD PMID:23460287 PMID:22763474 PMID:22308016 PMID:20351341 PMID:23357179 RGD:7248767, RGD:7257530, RGD:7257524, RGD:7248777, RGD:7248768 NCBI chr 9:127,815,016...127,854,658
Ensembl chr 9:127,811,130...127,854,773 		JBrowse link
G ENTPD1 ectonucleoside triphosphate diphosphohydrolase 1 IEP protein:decreased expression:abdominal fascia: RGD PMID:17469012 RGD:9685457 NCBI chr10:95,694,186...95,877,266
Ensembl chr10:95,711,779...95,877,266 		JBrowse link
G EPAS1 endothelial PAS domain protein 1 IEP RGD PMID:11159352 RGD:1580974 NCBI chr 2:46,297,407...46,386,697
Ensembl chr 2:46,293,667...46,386,697 		JBrowse link
G EPHX1 epoxide hydrolase 1 IAGP
EXP		 DNA:polymorphism
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:11283205 PMID:12173035 PMID:11283205 RGD:1601064 NCBI chr 1:225,810,124...225,845,563
Ensembl chr 1:225,810,124...225,845,563 		JBrowse link
G ERBB2 erb-b2 receptor tyrosine kinase 2 IEP RGD PMID:9158311 RGD:1580990 NCBI chr17:39,688,094...39,728,658
Ensembl chr17:39,687,914...39,730,426 		JBrowse link
G ESR2 estrogen receptor 2 IAGP RGD PMID:15894829 RGD:1581016 NCBI chr14:64,226,707...64,338,613
Ensembl chr14:64,084,232...64,338,112 		JBrowse link
G F2 coagulation factor II, thrombin severity IAGP DNA:polymorphism: :20210G>A(human) RGD PMID:16246971 RGD:6893628 NCBI chr11:46,719,213...46,739,506
Ensembl chr11:46,719,196...46,739,506 		JBrowse link
G F2R coagulation factor II thrombin receptor IEP RGD PMID:12161502 RGD:1581033 NCBI chr 5:76,716,126...76,735,770
Ensembl chr 5:76,716,126...76,735,770 		JBrowse link
G F3 coagulation factor III, tissue factor IEP associated with Fetal Death;protein:increased expression:plasma RGD PMID:19736615 RGD:11340220 NCBI chr 1:94,529,173...94,541,759
Ensembl chr 1:94,529,173...94,541,759 		JBrowse link
G F5 coagulation factor V severity IAGP DNA:mutation: :1691G>A(human) RGD PMID:16246971 RGD:6893628 NCBI chr 1:169,511,951...169,586,481
Ensembl chr 1:169,511,951...169,586,588 		JBrowse link
G FABP4 fatty acid binding protein 4 IEP protein:increased expression:blood serum (human) RGD PMID:19573524 RGD:329845853 NCBI chr 8:81,478,419...81,483,233
Ensembl chr 8:81,478,419...81,483,236 		JBrowse link
G FAS Fas cell surface death receptor susceptibility IAGP DNA:SNP:promoter:-670A>G (human)
DNA:SNP:promoter:-670A>G(rs1800682)(human)		 RGD PMID:15695771 PMID:30066360 RGD:12903973, RGD:14700669 NCBI chr10:88,964,050...89,017,059
Ensembl chr10:88,953,813...89,029,605 		JBrowse link
G FASLG Fas ligand susceptibility IAGP DNA:SNP:intron:124A>G(rs5030772)(human) RGD PMID:30066360 RGD:14700669 NCBI chr 1:172,659,103...172,666,876
Ensembl chr 1:172,659,103...172,666,876 		JBrowse link
G FLT1 fms related receptor tyrosine kinase 1 IDA
IEP
EXP		 mRNA,protein:increased expression:placenta
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:18679377 PMID:28628106 PMID:15472115 PMID:22262697 RGD:1582493, RGD:243048428 NCBI chr13:28,300,346...28,495,128
Ensembl chr13:28,300,346...28,495,145 		JBrowse link
G GAMT guanidinoacetate N-methyltransferase IEP mRNA:increased expression:placenta RGD PMID:31991880 RGD:329961300 NCBI chr19:1,397,026...1,401,542
Ensembl chr19:1,397,026...1,401,570 		JBrowse link
G GATA2 GATA binding protein 2 onset IEP RGD PMID:30659233 RGD:401850546 NCBI chr 3:128,479,422...128,493,201
Ensembl chr 3:128,479,427...128,493,201 		JBrowse link
G GATM glycine amidinotransferase IEP mRNA:increased expression:placenta RGD PMID:31991880 RGD:329961300 NCBI chr15:45,361,124...45,402,227
Ensembl chr15:45,361,124...45,402,327 		JBrowse link
G GC GC vitamin D binding protein IEP mRNA:decreased expression:placenta (human) RGD PMID:32682061 RGD:401901078 NCBI chr 4:71,741,693...71,805,520
Ensembl chr 4:71,741,696...71,804,041 		JBrowse link
G GPX1 glutathione peroxidase 1 IEP protein:decreased expression:placenta
mRNA:decreased expression:placenta		 RGD PMID:20303587 PMID:18852388 PMID:28705740 RGD:401827170, RGD:401827849, RGD:401827825 NCBI chr 3:49,357,176...49,358,353
Ensembl chr 3:49,357,174...49,358,605 		JBrowse link
G GPX3 glutathione peroxidase 3 IEP protein:decreased expression:placenta
mRNA:decreased expression:placenta		 RGD PMID:20303587 PMID:18852388 PMID:28705740 RGD:401827170, RGD:401827849, RGD:401827825 NCBI chr 5:151,020,591...151,028,988
Ensembl chr 5:151,020,591...151,028,988 		JBrowse link
G GPX4 glutathione peroxidase 4 IEP protein:decreased expression:placenta
mRNA:decreased expression:placenta		 RGD PMID:20303587 PMID:18852388 RGD:401827170, RGD:401827849 NCBI chr19:1,103,994...1,106,779
Ensembl chr19:1,103,982...1,106,791 		JBrowse link
G GSN gelsolin disease_progression IEP protein:decreased expression:blood plasma (human) RGD PMID:24239294 RGD:329337339 NCBI chr 9:121,201,483...121,332,842
Ensembl chr 9:121,207,794...121,332,843 		JBrowse link
G GSTP1 glutathione S-transferase pi 1 susceptibility IAGP DNA:missense mutation:cds:p.I105V (human) RGD PMID:11826024 RGD:737707 NCBI chr11:67,583,812...67,586,653
Ensembl chr11:67,583,742...67,586,656 		JBrowse link
G H19 H19 imprinted maternally expressed transcript ameliorates ISO
IEP		 RNA:increased expression:placenta (human) RGD PMID:31203154 PMID:29522949 RGD:213230155, RGD:242905198 NCBI chr11:1,995,176...2,001,266
Ensembl chr11:1,995,165...2,004,552 		JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha IEP protein:increased expression:chorionic villus (human) RGD PMID:22840297 RGD:155631283 NCBI chr14:61,695,513...61,748,258
Ensembl chr14:61,695,513...61,748,259 		JBrowse link
G HLA-A major histocompatibility complex, class I, A susceptibility IAGP DNA:polymorphism::HLA-A24:02(human)
DNA:SNPs::multiple		 RGD PMID:33126849 PMID:19727231 RGD:401827097, RGD:401827098 NCBI chr 6:29,942,532...29,945,870
Ensembl chr 6:29,941,260...29,949,572 		JBrowse link
G HLA-DQB1 major histocompatibility complex, class II, DQ beta 1 susceptibility IAGP DNA:polymorphism:cds:HLA-DQB1*04 (human) RGD PMID:10960630 RGD:36174024 NCBI chr 6:32,659,467...32,666,657
Ensembl chr 6:32,659,467...32,668,383 		JBrowse link
G HMOX1 heme oxygenase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:22197494 NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214 		JBrowse link
G HNF1A HNF1 homeobox A susceptibility IAGP associated with gestational diabetes;DNA:SNP:cd: p.I27L (rs1169288) (human) RGD PMID:31825269 RGD:329901812 NCBI chr12:120,978,543...121,002,512
Ensembl chr12:120,978,543...121,002,512 		JBrowse link
G HP haptoglobin severity IEP
IAGP		 protein:increased expression
DNA:polymorphism		 RGD PMID:17220952 PMID:16879055 RGD:1626337, RGD:1626343 NCBI chr16:72,054,505...72,061,055
Ensembl chr16:72,054,505...72,061,055 		JBrowse link
G HSD11B1 hydroxysteroid 11-beta dehydrogenase 1 susceptibility IAGP DNA:SNPs,haplotype: (rs2235543,rs846910) (human) RGD PMID:23659736 RGD:329901926 NCBI chr 1:209,686,179...209,734,929
Ensembl chr 1:209,686,178...209,734,949 		JBrowse link
G ICAM1 intercellular adhesion molecule 1 treatment ISO RGD PMID:21830843 RGD:8547718 NCBI chr19:10,271,120...10,286,615
Ensembl chr19:10,271,093...10,286,615 		JBrowse link
G IDO1 indoleamine 2,3-dioxygenase 1 ISS OMIM:189800 | OMIM:609402 | OMIM:609403 | OMIM:609404 | OMIM:614592 MouseDO NCBI chr 8:39,913,891...39,928,790
Ensembl chr 8:39,902,275...39,928,790 		JBrowse link
G IL1RN interleukin 1 receptor antagonist IEP protein:increased expression:serum (human) RGD PMID:21126355 RGD:6906962 NCBI chr 2:113,099,360...113,134,014
Ensembl chr 2:113,099,315...113,134,016 		JBrowse link
G IL6 interleukin 6 ameliorates ISO RGD PMID:31203154 RGD:213230155 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
G INHBA inhibin subunit beta A EXP CTD Direct Evidence: marker/mechanism CTD PMID:17332518 NCBI chr 7:41,685,114...41,705,406
Ensembl chr 7:41,667,168...41,705,834 		JBrowse link
G ISCU iron-sulfur cluster assembly enzyme IEP mRNA:decreased expression:chorionic villus (human) RGD PMID:22840297 RGD:155631283 NCBI chr12:108,561,463...108,569,384
Ensembl chr12:108,562,582...108,569,368 		JBrowse link
G ITGA4 integrin subunit alpha 4 ISO protein:increased expression:blood, granulocyte (rat) RGD PMID:10694336 RGD:9698441 NCBI chr 2:181,457,205...181,538,940
Ensembl chr 2:181,457,202...181,538,940 		JBrowse link
G ITGAM integrin subunit alpha M IAGP
IEP		 DNA:missense mutations:CDS:p.M441K (rs1143680), p.T1000N (rs41321249) (human)
protein:increased expression:neutrophil (human)
associated with Fetal Growth Retardation;mRNA:decreased expression:placenta (human)		 RGD PMID:33539617 PMID:18437152 PMID:32014817 RGD:329853770, RGD:329901825, RGD:329901659 NCBI chr16:31,259,975...31,332,877
Ensembl chr16:31,259,967...31,332,892 		JBrowse link
G ITPR1 inositol 1,4,5-trisphosphate receptor type 1 IEP mRNA:decreased expression:placenta (human) RGD PMID:36477942 RGD:401901174 NCBI chr 3:4,493,348...4,847,506
Ensembl chr 3:4,493,345...4,847,506 		JBrowse link
G ITPR2 inositol 1,4,5-trisphosphate receptor type 2 IEP mRNA:decreased expression:placenta (human) RGD PMID:36477942 RGD:401901174 NCBI chr12:26,335,352...26,833,194
Ensembl chr12:26,335,352...26,833,194 		JBrowse link
G ITPR3 inositol 1,4,5-trisphosphate receptor type 3 IEP mRNA:decreased expression:placenta (human) RGD PMID:36477942 RGD:401901174 NCBI chr 6:33,621,322...33,696,562
Ensembl chr 6:33,620,365...33,696,574 		JBrowse link
G KCNN4 potassium calcium-activated channel subfamily N member 4 IEP protein:decreased expression:umbilical artery,umbilical vein (human) RGD PMID:23261940 RGD:329955574 NCBI chr19:43,766,533...43,780,973
Ensembl chr19:43,766,533...43,780,976 		JBrowse link
G KISS1 KiSS-1 metastasis suppressor IEP mRNA:decreased expression:whole blood RGD PMID:16952198 RGD:2292128 NCBI chr 1:204,190,341...204,196,491
Ensembl chr 1:204,190,341...204,196,491 		JBrowse link
G LCN2 lipocalin 2 IEP protein:increased expression:serum,urine RGD PMID:23957217 RGD:126781721 NCBI chr 9:128,149,453...128,153,453
Ensembl chr 9:128,149,071...128,153,453 		JBrowse link
G LEP leptin ISO protein:decreased expression:plasma RGD PMID:16021089 RGD:5128718 NCBI chr 7:128,241,278...128,257,629
Ensembl chr 7:128,241,278...128,257,629 		JBrowse link
G LEPR leptin receptor ISO protein:increased expression:placenta RGD PMID:16021089 RGD:5128718 NCBI chr 1:65,420,652...65,641,559
Ensembl chr 1:65,420,652...65,641,559 		JBrowse link
G MIR1233-1 microRNA 1233-1 severity IEP miRNA:increased expression:blood serum (human) RGD PMID:25017274 RGD:155882496 NCBI chr15:34,382,069...34,382,150
Ensembl chr15:34,382,069...34,382,150 		JBrowse link
G MIR126 microRNA 126 HEP
IEP		 miRNA:decreased expression:blood serum (human) RGD PMID:25017274 PMID:30659233 RGD:155882496, RGD:401850546 NCBI chr 9:136,670,602...136,670,686
Ensembl chr 9:136,670,602...136,670,686 		JBrowse link
G MIR144 microRNA 144 IEP miRNA:decreased expression:blood serum (human) RGD PMID:25017274 RGD:155882496 NCBI chr17:28,861,533...28,861,618
Ensembl chr17:28,861,533...28,861,618 		JBrowse link
G MIR148A microRNA 148a ameliorates ISO RGD PMID:31203154 RGD:213230155 NCBI chr 7:25,949,919...25,949,986
Ensembl chr 7:25,949,919...25,949,986 		JBrowse link
G MIR152 microRNA 152 ISO
HEP		 miRNA:increased expression:placenta
miRNA:increased expression:blood serum (human) 		RGD PMID:31114978 PMID:25017274 RGD:21066344, RGD:155882496 NCBI chr17:48,037,161...48,037,247
Ensembl chr17:48,037,161...48,037,247 		JBrowse link
G MIR155 microRNA 155 IEP miRNA:increased expression:blood serum (human) RGD PMID:28700503 RGD:155882490 NCBI chr21:25,573,980...25,574,044
Ensembl chr21:25,573,980...25,574,044 		JBrowse link
G MIR15B microRNA 15b HEP miRNA:decreased expression:blood serum (human) RGD PMID:25017274 RGD:155882496 NCBI chr 3:160,404,588...160,404,685
Ensembl chr 3:160,404,588...160,404,685 		JBrowse link
G MIR193A microRNA 193a HEP miRNA:increased expression:blood serum (human) RGD PMID:25017274 RGD:155882496 NCBI chr17:31,559,996...31,560,083
Ensembl chr17:31,559,996...31,560,083 		JBrowse link
G MIR204 microRNA 204 HEP miRNA:increased expression:blood serum (human) RGD PMID:25017274 RGD:155882496 NCBI chr 9:70,809,975...70,810,084
Ensembl chr 9:70,809,975...70,810,084 		JBrowse link
G MIR210 microRNA 210 disease_progression
severity		 IEP miRNA:increased expression:placenta (human)
miRNA:increased expression:blood serum (human)
miRNA:increased expression:chorionic villus (human)
miRNA:increased expression:blood plasma (human)		 RGD PMID:27746364 PMID:25017274 PMID:28700503 PMID:22840297 PMID:21388517 RGD:155260325, RGD:155882496, RGD:155882490, RGD:155631283, RGD:155269044 NCBI chr11:568,089...568,198
Ensembl chr11:568,089...568,198 		JBrowse link
G MIR216A microRNA 216a ameliorates ISO RGD PMID:31203154 RGD:213230155 NCBI chr 2:55,988,950...55,989,059
Ensembl chr 2:55,988,950...55,989,059 		JBrowse link
G MIR25 microRNA 25 HEP miRNA:increased expression:blood serum (human) RGD PMID:25017274 RGD:155882496 NCBI chr 7:100,093,560...100,093,643
Ensembl chr 7:100,093,560...100,093,643 		JBrowse link
G MIR296 microRNA 296 HEP miRNA:increased expression:blood serum (human) RGD PMID:25017274 RGD:155882496 NCBI chr20:58,817,615...58,817,694
Ensembl chr20:58,817,615...58,817,694 		JBrowse link
G MIR32 microRNA 32 HEP miRNA:increased expression:blood serum (human) RGD PMID:25017274 RGD:155882496 NCBI chr 9:109,046,229...109,046,298
Ensembl chr 9:109,046,229...109,046,298 		JBrowse link
G MIR335 microRNA 335 HEP miRNA:decreased expression:blood serum (human) RGD PMID:25017274 RGD:155882496 NCBI chr 7:130,496,111...130,496,204
Ensembl chr 7:130,496,111...130,496,204 		JBrowse link
G MIR423 microRNA 423 IEP miRNA:increased expression:plasma RGD PMID:30587375 RGD:158014896 NCBI chr17:30,117,079...30,117,172
Ensembl chr17:30,117,079...30,117,172 		JBrowse link
G MIR518B microRNA 518b HEP miRNA:increased expression:blood serum (human) RGD PMID:25017274 RGD:155882496 NCBI chr19:53,702,737...53,702,819
Ensembl chr19:53,702,737...53,702,819 		JBrowse link
G MIR520A microRNA 520a IEP miRNA:increased expression:blood serum (human) RGD PMID:25017274 RGD:155882496 NCBI chr19:53,690,881...53,690,965
Ensembl chr19:53,690,881...53,690,965 		JBrowse link
G MIR650 microRNA 650 HEP miRNA:increased expression:blood serum (human) RGD PMID:25017274 RGD:155882496 NCBI chr22:22,822,776...22,822,871
Ensembl chr22:22,822,776...22,822,871 		JBrowse link
G MIR668 microRNA 668 HEP miRNA:decreased expression:blood serum (human) RGD PMID:25017274 RGD:155882496 NCBI chr14:101,055,258...101,055,323
Ensembl chr14:101,055,258...101,055,323 		JBrowse link
G MMP2 matrix metallopeptidase 2 IEP mRNA, protein:decreased expression:placenta RGD PMID:17083831 RGD:2290399 NCBI chr16:55,478,830...55,506,691
Ensembl chr16:55,389,700...55,506,691 		JBrowse link
G MMP9 matrix metallopeptidase 9 IEP
ISO		 mRNA, protein:decreased expression:placenta RGD PMID:17083831 PMID:23776237 RGD:2290399, RGD:13204787 NCBI chr20:46,008,908...46,016,561
Ensembl chr20:46,008,908...46,016,561 		JBrowse link
G NOS3 nitric oxide synthase 3 treatment ISO
EXP		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:29250138 RGD:13504712 NCBI chr 7:150,991,017...151,014,588
Ensembl chr 7:150,991,017...151,014,588 		JBrowse link
G NOTCH2 notch receptor 2 ISS OMIM:189800 | OMIM:609402 | OMIM:609403 | OMIM:609404 | OMIM:614592 MouseDO NCBI chr 1:119,911,553...120,069,662
Ensembl chr 1:119,911,553...120,100,779 		JBrowse link
G NR1H3 nuclear receptor subfamily 1 group H member 3 exacerbates IEP mRNA, protein:increased expression:placenta (human)
mRNA:altered expression:placenta, adipose tissue (human)		 RGD PMID:28352810 PMID:20655109 RGD:401842369, RGD:401850787 NCBI chr11:47,248,300...47,269,033
Ensembl chr11:47,248,300...47,269,033 		JBrowse link
G NSD1 nuclear receptor binding SET domain protein 1 IAGP ClinVar Annotator: match by term: Preeclampsia ClinVar PMID:12464997 PMID:12807965 PMID:15942875 PMID:17565729 PMID:18414213 More... NCBI chr 5:177,131,798...177,300,213
Ensembl chr 5:177,131,830...177,300,213 		JBrowse link
G OGG1 8-oxoguanine DNA glycosylase IEP mRNA:increased expression:placenta (human) RGD PMID:36477942 RGD:401901174 NCBI chr 3:9,749,952...9,783,108
Ensembl chr 3:9,749,944...9,788,219 		JBrowse link
G PDCD1 programmed cell death 1 treatment IEP
ISO		 protein:increased expression:Treg cell RGD PMID:27277012 PMID:27277012 RGD:40886269, RGD:40886269 NCBI chr 2:241,849,884...241,858,894
Ensembl chr 2:241,849,884...241,858,894 		JBrowse link
G PDE5A phosphodiesterase 5A ISO RGD PMID:18538317 RGD:2314465 NCBI chr 4:119,494,403...119,628,804
Ensembl chr 4:119,494,397...119,628,804 		JBrowse link
G PEG10 paternally expressed 10 onset IEP mRNA, protein:decreased expression:placenta (human)
mRNA, protein:increased expression:placenta (human)		 RGD PMID:37464405 PMID:25526181 PMID:22137777 RGD:401851069, RGD:401851074, RGD:401851073 NCBI chr 7:94,656,325...94,669,695
Ensembl chr 7:94,656,325...94,669,695 		JBrowse link
G PGF placental growth factor IEP
ISO		 RGD PMID:21756887 PMID:20720407 RGD:6483577, RGD:6483779 NCBI chr14:74,941,830...74,955,764
Ensembl chr14:74,941,834...74,955,626 		JBrowse link
G PLAUR plasminogen activator, urokinase receptor IEP protein:increased expression:plasma RGD PMID:21722073 RGD:6484119 NCBI chr19:43,646,095...43,670,169
Ensembl chr19:43,646,095...43,670,547 		JBrowse link
G PML PML nuclear body scaffold IEP mRNA:decreased expression:placenta (human) RGD PMID:20228380 RGD:41404689 NCBI chr15:73,994,716...74,047,827
Ensembl chr15:73,994,673...74,047,827 		JBrowse link
G PPARG peroxisome proliferator activated receptor gamma IDA
EXP		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:34995009 PMID:15562025 RGD:1580687 NCBI chr 3:12,287,368...12,434,344
Ensembl chr 3:12,287,368...12,434,356 		JBrowse link
G PROC protein C, inactivator of coagulation factors Va and VIIIa IDA RGD PMID:9065198 RGD:11564336 NCBI chr 2:127,418,427...127,429,242
Ensembl chr 2:127,418,427...127,429,242 		JBrowse link
G PTGS1 prostaglandin-endoperoxide synthase 1 ISS OMIM:189800 | OMIM:609402 | OMIM:609403 | OMIM:609404 | OMIM:614592 MouseDO NCBI chr 9:122,370,533...122,395,703
Ensembl chr 9:122,370,530...122,395,703 		JBrowse link
G PTPN2 protein tyrosine phosphatase non-receptor type 2 disease_progression IEP mRNA:decreased expression:placenta (human) RGD PMID:27746364 RGD:155260325 NCBI chr18:12,785,478...12,884,237
Ensembl chr18:12,785,478...12,929,643 		JBrowse link
G RARRES2 retinoic acid receptor responder 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:34398343 NCBI chr 7:150,338,329...150,341,629
Ensembl chr 7:150,338,317...150,341,662 		JBrowse link
G RBP4 retinol binding protein 4 disease_progression IEP protein:increased expression:blood serum (human)
protein:decreased expression:umbilical cord,blood serum (human)		 RGD PMID:21173508 PMID:21299359 RGD:329845578, RGD:329845866 NCBI chr10:93,591,694...93,601,744
Ensembl chr10:93,591,687...93,601,744 		JBrowse link
G ROBO1 roundabout guidance receptor 1 IEP mRNA,protein:increased expression:placenta RGD PMID:22262697 RGD:243048428 NCBI chr 3:78,597,239...79,767,998
Ensembl chr 3:78,597,239...79,767,998 		JBrowse link
G ROBO4 roundabout guidance receptor 4 IEP mRNA,protein:increased expression:placenta RGD PMID:22262697 RGD:243048428 NCBI chr11:124,883,691...124,897,865
Ensembl chr11:124,883,691...124,898,500 		JBrowse link
G RYR1 ryanodine receptor 1 IEP mRNA:decreased expression:placenta (human) RGD PMID:36477942 RGD:401901174 NCBI chr19:38,433,691...38,587,564
Ensembl chr19:38,433,691...38,595,273 		JBrowse link
G RYR2 ryanodine receptor 2 IEP mRNA:decreased expression:placenta (human) RGD PMID:36477942 RGD:401901174 NCBI chr 1:237,042,184...237,833,988
Ensembl chr 1:237,042,184...237,833,988 		JBrowse link
G RYR3 ryanodine receptor 3 IEP mRNA:decreased expression:placenta (human) RGD PMID:36477942 RGD:401901174 NCBI chr15:33,310,967...33,866,102
Ensembl chr15:33,310,962...33,866,121 		JBrowse link
G S100G S100 calcium binding protein G IEP mRNA:decreased expression:placenta (human) RGD PMID:36477942 RGD:401901174 NCBI chr  X:16,650,158...16,654,670
Ensembl chr  X:16,650,158...16,654,670 		JBrowse link
G SCNN1A sodium channel epithelial 1 subunit alpha EXP CTD Direct Evidence: marker/mechanism CTD PMID:16555725 NCBI chr12:6,346,847...6,377,359
Ensembl chr12:6,346,843...6,377,730 		JBrowse link
G SERPINA1 serpin family A member 1 IEP RGD PMID:1852102 RGD:1643155 NCBI chr14:94,376,747...94,390,635
Ensembl chr14:94,376,747...94,390,693 		JBrowse link
G SERPINE1 serpin family E member 1 IEP
EXP		 mRNA:increased expression:blood:
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:18679377 PMID:16952198 RGD:2292128 NCBI chr 7:101,127,104...101,139,247
Ensembl chr 7:101,127,104...101,139,247 		JBrowse link
G SERPINF2 serpin family F member 2 IEP protein:increased expression:urine RGD PMID:1334334 RGD:1625535 NCBI chr17:1,742,871...1,755,265
Ensembl chr17:1,742,836...1,755,265 		JBrowse link
G SLC2A1 solute carrier family 2 member 1 IEP mRNA:decreased expression:chorionic villus (human) RGD PMID:22840297 RGD:155631283 NCBI chr 1:42,925,353...42,958,868
Ensembl chr 1:42,925,353...42,958,893 		JBrowse link
G STOX1 storkhead box 1 no_association IAGP
IMP		 DNA:missense mutation:cds:p.Y153H (human)
human fetally expressed gene in a mouse model		 RGD PMID:15806103 PMID:23357179 PMID:17617193 RGD:11553888, RGD:7248768, RGD:11553890 NCBI chr10:68,827,531...68,895,432
Ensembl chr10:68,827,531...68,895,432 		JBrowse link
G TFPI tissue factor pathway inhibitor IEP protein:increased expression:plasma: RGD PMID:10078579 RGD:11060132 NCBI chr 2:187,464,230...187,554,435
Ensembl chr 2:187,464,230...187,565,760 		JBrowse link
G TIMP1 TIMP metallopeptidase inhibitor 1 IEP mRNA, protein:increased expression:placenta RGD PMID:17083831 RGD:2290399 NCBI chr  X:47,582,436...47,586,789
Ensembl chr  X:47,582,408...47,586,789 		JBrowse link
G TLR3 toll like receptor 3 ISO protein:increased expression:placenta (rat) RGD PMID:19779466 RGD:5128769 NCBI chr 4:186,069,156...186,088,073
Ensembl chr 4:186,068,911...186,088,073 		JBrowse link
G TLR4 toll like receptor 4 IEP RGD PMID:16157088 RGD:1580682 NCBI chr 9:117,704,403...117,724,735
Ensembl chr 9:117,704,175...117,724,735 		JBrowse link
G TNF tumor necrosis factor ameliorates IAGP
ISO		 RGD PMID:15901845 PMID:31203154 RGD:1580314, RGD:213230155 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
G TNFRSF1B TNF receptor superfamily member 1B IDA human protein in rat model RGD PMID:21505354 RGD:5131211 NCBI chr 1:12,166,991...12,209,220
Ensembl chr 1:12,166,991...12,209,228 		JBrowse link
G TRPV5 transient receptor potential cation channel subfamily V member 5 IEP mRNA:decreased expression:placenta (human) RGD PMID:36477942 RGD:401901174 NCBI chr 7:142,908,101...142,933,746
Ensembl chr 7:142,908,101...142,933,746 		JBrowse link
G TRPV6 transient receptor potential cation channel subfamily V member 6 IEP mRNA:decreased expression:placenta (human) RGD PMID:36477942 RGD:401901174 NCBI chr 7:142,871,208...142,885,745
Ensembl chr 7:142,871,208...142,885,745 		JBrowse link
G UTS2 urotensin 2 IEP RGD PMID:15866083 RGD:1580806 NCBI chr 1:7,847,612...7,913,249
Ensembl chr 1:7,843,083...7,853,512 		JBrowse link
G VDR vitamin D receptor IEP protein:decreased expression:placenta (human)
mRNA:decreased expression:placenta (human)
associated with Premature Birth; mRNA:increased expression:placenta (human)		 RGD PMID:22871339 PMID:36477942 PMID:32682061 RGD:401901075, RGD:401901174, RGD:401901078 NCBI chr12:47,841,537...47,904,994
Ensembl chr12:47,841,537...47,943,048 		JBrowse link
G VEGFA vascular endothelial growth factor A IAGP
IEP		 mRNA:decreased expression:chorionic villus (human) RGD PMID:16517614 PMID:22840297 RGD:1580566, RGD:155631283 NCBI chr 6:43,770,211...43,786,487
Ensembl chr 6:43,770,184...43,786,487 		JBrowse link
Preeclampsia/Eclampsia 4 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G STOX1 storkhead box 1 IAGP
EXP		 ClinVar Annotator: match by term: Preeclampsia/eclampsia 4
CTD Direct Evidence: marker/mechanism		 ClinVar
CTD
OMIM		 PMID:15806103 PMID:17325670 PMID:25741868 PMID:33116287 NCBI chr10:68,827,531...68,895,432
Ensembl chr10:68,827,531...68,895,432 		JBrowse link
Preeclampsia/Eclampsia 5 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CORIN corin, serine peptidase IAGP ClinVar Annotator: match by term: Preeclampsia/eclampsia 5 OMIM
ClinVar		 PMID:22437503 PMID:24828501 PMID:25741868 PMID:28492532 NCBI chr 4:47,594,001...47,838,067
Ensembl chr 4:47,593,999...47,838,106 		JBrowse link
Preeclamptic Toxemia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G PECAM1 platelet and endothelial cell adhesion molecule 1 IDA RGD PMID:22534418 RGD:6771230 NCBI chr17:64,319,415...64,390,860
Ensembl chr17:64,319,415...64,413,776 		JBrowse link
G REN renin IEP protein:increased activity:blood plasma (human) RGD PMID:683663 RGD:125097480 NCBI chr 1:204,154,819...204,166,337
Ensembl chr 1:204,154,819...204,190,324 		JBrowse link
Pregnancy-Induced Hypertension term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACE angiotensin I converting enzyme ISO RGD PMID:17977916 RGD:8548898 NCBI chr17:63,477,061...63,498,373
Ensembl chr17:63,477,061...63,498,380 		JBrowse link
G ACE2 angiotensin converting enzyme 2 ISO RGD PMID:17977916 RGD:8548898 NCBI chr  X:15,518,197...15,607,211
Ensembl chr  X:15,494,566...15,607,236 		JBrowse link
G AGT angiotensinogen ISO RGD PMID:17977916 RGD:8548898 NCBI chr 1:230,702,523...230,745,583
Ensembl chr 1:230,690,776...230,745,576 		JBrowse link
G EDN1 endothelin 1 no_association IAGP DNA:transversion:exon:p.K198N rs5370 (human) RGD PMID:19730395 PMID:11593097 RGD:4145063, RGD:4145070 NCBI chr 6:12,230,516...12,297,194
Ensembl chr 6:12,290,361...12,297,194 		JBrowse link
G GPX3 glutathione peroxidase 3 IEP protein:increased expression:plasma RGD PMID:8244188 RGD:401827853 NCBI chr 5:151,020,591...151,028,988
Ensembl chr 5:151,020,591...151,028,988 		JBrowse link
G HMOX1 heme oxygenase 1 treatment ISO RGD PMID:21383306 RGD:10755723 NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214 		JBrowse link
G HP haptoglobin EXP CTD Direct Evidence: marker/mechanism CTD PMID:16597321 NCBI chr16:72,054,505...72,061,055
Ensembl chr16:72,054,505...72,061,055 		JBrowse link
G NOS3 nitric oxide synthase 3 EXP
IAGP		 CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Hypertension, pregnancy-induced, susceptibility to		 CTD
ClinVar		 PMID:9737779 PMID:9894802 PMID:10475066 PMID:10510054 PMID:10514107 More... NCBI chr 7:150,991,017...151,014,588
Ensembl chr 7:150,991,017...151,014,588 		JBrowse link
G RBP4 retinol binding protein 4 IEP protein:increased expression, decreased expression:blood serum, umbilical cord blood (human) RGD PMID:19708176 RGD:329849109 NCBI chr10:93,591,694...93,601,744
Ensembl chr10:93,591,687...93,601,744 		JBrowse link
G TFPI tissue factor pathway inhibitor ISO mRNA:decreased expression:aorta: RGD PMID:26104991 RGD:11062065 NCBI chr 2:187,464,230...187,554,435
Ensembl chr 2:187,464,230...187,565,760 		JBrowse link
G TNF tumor necrosis factor treatment ISO RGD PMID:18981324 RGD:13825265 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
primary pulmonary hypertension term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABI2 abl interactor 2 IAGP ClinVar Annotator: match by term: Primary pulmonary hypertension ClinVar PMID:28492532 PMID:31727138 NCBI chr 2:203,328,394...203,432,169
Ensembl chr 2:203,328,280...203,447,728 		JBrowse link
G ACADL acyl-CoA dehydrogenase long chain IAGP ClinVar Annotator: match by term: Primary pulmonary hypertension ClinVar PMID:28492532 PMID:31727138 NCBI chr 2:210,187,923...210,225,447
Ensembl chr 2:210,187,126...210,225,447 		JBrowse link
G ACVRL1 activin A receptor like type 1 IAGP ClinVar Annotator: match by term: Heritable pulmonary arterial hypertension ClinVar PMID:25741868 PMID:28492532 PMID:31727138 NCBI chr12:51,906,944...51,923,361
Ensembl chr12:51,906,908...51,923,361 		JBrowse link
G ADAM23 ADAM metallopeptidase domain 23 IAGP ClinVar Annotator: match by term: Primary pulmonary hypertension ClinVar PMID:28492532 PMID:31727138 NCBI chr 2:206,443,532...206,621,127
Ensembl chr 2:206,443,532...206,621,127 		JBrowse link
G ADORA2A adenosine A2a receptor ISS OMIM:178600 | OMIM:265400 | OMIM:615342 | OMIM:615343 | OMIM:615344 MouseDO NCBI chr22:24,423,597...24,442,357
Ensembl chr22:24,417,879...24,442,357 		JBrowse link
G ALS2 alsin Rho guanine nucleotide exchange factor ALS2 IAGP ClinVar Annotator: match by term: Primary pulmonary hypertension ClinVar PMID:16429395 PMID:16429403 PMID:27453251 PMID:28492532 PMID:29743074 NCBI chr 2:201,700,267...201,780,933
Ensembl chr 2:201,700,267...201,782,112 		JBrowse link
G BMPR1B bone morphogenetic protein receptor type 1B IAGP ClinVar Annotator: match by term: Idiopathic pulmonary arterial hypertension ClinVar PMID:22374147 PMID:25741868 PMID:25758993 PMID:28492532 NCBI chr 4:94,757,955...95,158,450
Ensembl chr 4:94,757,955...95,158,448 		JBrowse link
G BMPR2 bone morphogenetic protein receptor type 2 EXP
IAGP
ISS		 CTD Direct Evidence: marker/mechanism
ClinVar Annotator: match by term: Primary pulmonary hypertension
ClinVar Annotator: match by term: Pulmonary hypertension, primary, fenfluramine-associated
ClinVar Annotator: match by term: Pulmonary hypertension, primary, dexfenfluramine-associated
OMIM:178600 | OMIM:265400 | OMIM:615342 | OMIM:615343 | OMIM:615344
ClinVar Annotator: match by term: Idiopathic and/or familial pulmonary arterial hypertension		 CTD
ClinVar
MouseDO		 PMID:3291115 PMID:9536098 PMID:10903931 PMID:10973254 PMID:11015450 More... NCBI chr 2:202,376,327...202,567,749
Ensembl chr 2:202,376,327...202,567,751 		JBrowse link
G C2orf80 chromosome 2 open reading frame 80 IAGP ClinVar Annotator: match by term: Primary pulmonary hypertension ClinVar PMID:28492532 PMID:31727138 NCBI chr 2:208,165,347...208,190,030
Ensembl chr 2:208,165,343...208,190,030 		JBrowse link
G CARF calcium responsive transcription factor IAGP ClinVar Annotator: match by term: Primary pulmonary hypertension ClinVar PMID:28492532 PMID:31727138 NCBI chr 2:202,912,275...202,988,263
Ensembl chr 2:202,912,214...202,988,263 		JBrowse link
G CAV1 caveolin 1 EXP CTD Direct Evidence: marker/mechanism CTD NCBI chr 7:116,525,009...116,561,185
Ensembl chr 7:116,524,994...116,561,179 		JBrowse link
G CCNYL1 cyclin Y like 1 IAGP ClinVar Annotator: match by term: Primary pulmonary hypertension ClinVar PMID:28492532 PMID:31727138 NCBI chr 2:207,711,640...207,756,174
Ensembl chr 2:207,711,540...207,761,839 		JBrowse link
G CD28 CD28 molecule IAGP ClinVar Annotator: match by term: Primary pulmonary hypertension ClinVar PMID:28492532 PMID:31727138 NCBI chr 2:203,706,482...203,738,912
Ensembl chr 2:203,706,517...203,739,756 		JBrowse link
G CDK15 cyclin dependent kinase 15 IAGP ClinVar Annotator: match by term: Primary pulmonary hypertension ClinVar PMID:16429395 PMID:16429403 PMID:27453251 PMID:28492532 PMID:29743074 NCBI chr 2:201,806,429...201,895,550
Ensembl chr 2:201,790,461...201,895,550 		JBrowse link
G CMKLR2 chemerin chemokine-like receptor 2 IAGP ClinVar Annotator: match by term: Primary pulmonary hypertension ClinVar PMID:28492532 PMID:31727138 NCBI chr 2:206,175,316...206,217,912
Ensembl chr 2:206,175,316...206,218,047 		JBrowse link
G CPO carboxypeptidase O IAGP ClinVar Annotator: match by term: Primary pulmonary hypertension ClinVar PMID:28492532 PMID:31727138 NCBI chr 2:206,939,518...206,969,474
Ensembl chr 2:206,939,518...206,969,474 		JBrowse link
G CPS1 carbamoyl-phosphate synthase 1 IAGP ClinVar Annotator: match by term: Primary pulmonary hypertension ClinVar PMID:28492532 PMID:31727138 NCBI chr 2:210,477,685...210,679,107
Ensembl chr 2:210,477,682...210,679,107 		JBrowse link
G CREB1 cAMP responsive element binding protein 1 IAGP ClinVar Annotator: match by term: Primary pulmonary hypertension ClinVar PMID:28492532 PMID:31727138 NCBI chr 2:207,529,962...207,605,988
Ensembl chr 2:207,529,737...207,605,988 		JBrowse link
G CRYGA crystallin gamma A IAGP ClinVar Annotator: match by term: Primary pulmonary hypertension ClinVar PMID:28492532 PMID:31727138 NCBI chr 2:208,160,740...208,163,589
Ensembl chr 2:208,160,740...208,163,589 		JBrowse link
G CRYGB crystallin gamma B IAGP ClinVar Annotator: match by term: Primary pulmonary hypertension ClinVar PMID:28492532 PMID:31727138 NCBI chr 2:208,142,573...208,146,158
Ensembl chr 2:208,142,573...208,146,158 		JBrowse link
G CRYGC crystallin gamma C IAGP ClinVar Annotator: match by term: Primary pulmonary hypertension ClinVar PMID:28492532 PMID:31727138 NCBI chr 2:208,128,137...208,129,828
Ensembl chr 2:208,128,137...208,129,828 		JBrowse link
G CRYGD crystallin gamma D IAGP ClinVar Annotator: match by term: Primary pulmonary hypertension ClinVar PMID:28492532 PMID:31727138 NCBI chr 2:208,121,607...208,124,524
Ensembl chr 2:208,121,607...208,124,524 		JBrowse link
G CTLA4 cytotoxic T-lymphocyte associated protein 4 IAGP ClinVar Annotator: match by term: Primary pulmonary hypertension ClinVar PMID:28492532 PMID:31727138 NCBI chr 2:203,867,771...203,873,965
Ensembl chr 2:203,853,888...203,873,965 		JBrowse link
G CYP20A1 cytochrome P450 family 20 subfamily A member 1 IAGP ClinVar Annotator: match by term: Primary pulmonary hypertension ClinVar PMID:28492532 PMID:31727138 NCBI chr 2:203,239,018...203,306,026
Ensembl chr 2:203,238,977...203,306,026 		JBrowse link
G DYTN dystrotelin IAGP ClinVar Annotator: match by term: Primary pulmonary hypertension ClinVar PMID:28492532 PMID:31727138 NCBI chr 2:206,651,621...206,718,396
Ensembl chr 2:206,651,621...206,721,570 		JBrowse link
G EEF1B2 eukaryotic translation elongation factor 1 beta 2 IAGP ClinVar Annotator: match by term: Primary pulmonary hypertension ClinVar PMID:28492532 PMID:31727138 NCBI chr 2:206,159,609...206,162,928
Ensembl chr 2:206,159,585...206,162,928 		JBrowse link
G FAM117B family with sequence similarity 117 member B IAGP ClinVar Annotator: match by term: Primary pulmonary hypertension ClinVar PMID:28492532 PMID:31727138 NCBI chr 2:202,634,969...202,769,757
Ensembl chr 2:202,634,969...202,769,757 		JBrowse link
G FASTKD2 FAST kinase domains 2 IAGP ClinVar Annotator: match by term: Primary pulmonary hypertension ClinVar PMID:28492532 PMID:31727138 NCBI chr 2:206,765,606...206,796,189
Ensembl chr 2:206,765,357...206,796,189 		JBrowse link
G FBXO32 F-box protein 32 IEP mRNA:increased expression:vastus lateralis RGD PMID:23972212 RGD:329812002 NCBI chr 8:123,497,889...123,541,206
Ensembl chr 8:123,497,889...123,541,206 		JBrowse link
G FGFR2 fibroblast growth factor receptor 2 IEP protein:increased expression:lung (human) RGD PMID:29722558 RGD:155791445 NCBI chr10:121,478,330...121,598,458
Ensembl chr10:121,478,332...121,598,458 		JBrowse link
G FOXF1 forkhead box F1 IAGP ClinVar Annotator: match by term: Idiopathic and/or familial pulmonary arterial hypertension ClinVar PMID:19500772 PMID:19592680 PMID:19812545 PMID:20425831 PMID:22766610 More... NCBI chr16:86,510,527...86,515,422
Ensembl chr16:86,510,527...86,515,422 		JBrowse link
G FZD5 frizzled class receptor 5 IAGP ClinVar Annotator: match by term: Primary pulmonary hypertension ClinVar PMID:28492532 PMID:31727138 NCBI chr 2:207,762,598...207,769,906
Ensembl chr 2:207,762,598...207,769,906 		JBrowse link
G FZD7 frizzled class receptor 7 IAGP ClinVar Annotator: match by term: Primary pulmonary hypertension ClinVar PMID:16429395 PMID:16429403 PMID:27453251 PMID:28492532 PMID:29743074 NCBI chr 2:202,033,855...202,038,441
Ensembl chr 2:202,033,855...202,038,441 		JBrowse link
G HDAC1 histone deacetylase 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:22711276 NCBI chr 1:32,292,083...32,333,626
Ensembl chr 1:32,292,083...32,333,635 		JBrowse link
G HDAC4 histone deacetylase 4 EXP CTD Direct Evidence: marker/mechanism CTD PMID:22711276 NCBI chr 2:239,048,168...239,401,649
Ensembl chr 2:239,048,168...239,401,654 		JBrowse link
G HDAC5 histone deacetylase 5 EXP CTD Direct Evidence: marker/mechanism CTD PMID:22711276 NCBI chr17:44,076,753...44,123,641
Ensembl chr17:44,076,746...44,123,702 		JBrowse link
G ICA1L islet cell autoantigen 1 like IAGP ClinVar Annotator: match by term: Primary pulmonary hypertension ClinVar PMID:28492532 PMID:31727138 NCBI chr 2:202,773,176...202,871,766
Ensembl chr 2:202,773,150...202,871,766 		JBrowse link
G ICOS inducible T cell costimulator IAGP ClinVar Annotator: match by term: Primary pulmonary hypertension ClinVar PMID:28492532 PMID:31727138 NCBI chr 2:203,936,763...203,961,577
Ensembl chr 2:203,936,763...203,961,577 		JBrowse link
G ID1 inhibitor of DNA binding 1 IEP protein:decreased expression:lung, wall of arteriole (human) RGD PMID:20522807 RGD:9686087 NCBI chr20:31,605,289...31,606,510
Ensembl chr20:31,573,014...31,606,515 		JBrowse link
G IDH1 isocitrate dehydrogenase (NADP(+)) 1 IAGP ClinVar Annotator: match by term: Primary pulmonary hypertension ClinVar PMID:28492532 PMID:31727138 NCBI chr 2:208,236,227...208,255,071
Ensembl chr 2:208,236,229...208,266,074 		JBrowse link
G INO80D INO80 complex subunit D IAGP ClinVar Annotator: match by term: Primary pulmonary hypertension ClinVar PMID:28492532 PMID:31727138 NCBI chr 2:205,993,721...206,086,174
Ensembl chr 2:205,993,721...206,086,303 		JBrowse link
G KANSL1L KAT8 regulatory NSL complex subunit 1 like IAGP ClinVar Annotator: match by term: Primary pulmonary hypertension ClinVar PMID:28492532 PMID:31727138 NCBI chr 2:210,021,421...210,172,760
Ensembl chr 2:210,021,421...210,171,409 		JBrowse link
G KCNK3 potassium two pore domain channel subfamily K member 3 EXP CTD Direct Evidence: marker/mechanism CTD NCBI chr 2:26,692,722...26,733,420
Ensembl chr 2:26,692,722...26,733,420 		JBrowse link
G KLF7 KLF transcription factor 7 IAGP ClinVar Annotator: match by term: Primary pulmonary hypertension ClinVar PMID:28492532 PMID:31727138 NCBI chr 2:207,074,137...207,173,851
Ensembl chr 2:207,074,137...207,173,856 		JBrowse link
G LANCL1 LanC like glutathione S-transferase 1 IAGP ClinVar Annotator: match by term: Primary pulmonary hypertension ClinVar PMID:28492532 PMID:31727138 NCBI chr 2:210,431,251...210,477,584
Ensembl chr 2:210,427,131...210,477,652 		JBrowse link
G LOC129935434 ATAC-STARR-seq lymphoblastoid silent region 12244 IAGP ClinVar Annotator: match by term: Primary pulmonary hypertension ClinVar PMID:19223935 PMID:25741868 PMID:28492532 NCBI chr 2:202,376,775...202,376,834 JBrowse link
G MAP2 microtubule associated protein 2 IAGP ClinVar Annotator: match by term: Primary pulmonary hypertension ClinVar PMID:28492532 PMID:31727138 NCBI chr 2:209,424,047...209,734,112
Ensembl chr 2:209,424,047...209,734,147 		JBrowse link
G MDH1B malate dehydrogenase 1B IAGP ClinVar Annotator: match by term: Primary pulmonary hypertension ClinVar PMID:28492532 PMID:31727138 NCBI chr 2:206,737,763...206,765,328
Ensembl chr 2:206,737,763...206,765,328 		JBrowse link
G METTL21A methyltransferase 21A, HSPA lysine IAGP ClinVar Annotator: match by term: Primary pulmonary hypertension ClinVar PMID:28492532 PMID:31727138 NCBI chr 2:207,580,635...207,626,053
Ensembl chr 2:207,580,631...207,625,928 		JBrowse link
G MFN1 mitofusin 1 IEP protein:decreased expression:vastus lateralis RGD PMID:23972212 RGD:329812002 NCBI chr 3:179,347,709...179,394,936
Ensembl chr 3:179,347,709...179,394,936 		JBrowse link
G MFN2 mitofusin 2 IEP protein:decreased expression:vastus lateralis RGD PMID:23972212 RGD:329812002 NCBI chr 1:11,980,444...12,013,508
Ensembl chr 1:11,980,181...12,015,211 		JBrowse link
G MIR23A microRNA 23a IEP RNA:increased expression:serum RGD PMID:25815108 RGD:155882560 NCBI chr19:13,836,587...13,836,659
Ensembl chr19:13,836,587...13,836,659 		JBrowse link
G MYL1 myosin light chain 1 IAGP ClinVar Annotator: match by term: Primary pulmonary hypertension ClinVar PMID:28492532 PMID:31727138 NCBI chr 2:210,290,150...210,315,174
Ensembl chr 2:210,290,150...210,315,174 		JBrowse link
G NBEAL1 neurobeachin like 1 IAGP ClinVar Annotator: match by term: Primary pulmonary hypertension ClinVar PMID:28492532 PMID:31727138 NCBI chr 2:203,014,608...203,225,194
Ensembl chr 2:203,014,608...203,226,378 		JBrowse link
G NDUFS1 NADH:ubiquinone oxidoreductase core subunit S1 IAGP ClinVar Annotator: match by term: Primary pulmonary hypertension ClinVar PMID:28492532 PMID:31727138 NCBI chr 2:206,114,817...206,159,444
Ensembl chr 2:206,114,817...206,159,509 		JBrowse link
G NOP58 NOP58 ribonucleoprotein IAGP ClinVar Annotator: match by term: Primary pulmonary hypertension ClinVar PMID:16429395 PMID:16429403 PMID:27453251 PMID:28492532 PMID:29743074 NCBI chr 2:202,265,763...202,303,661
Ensembl chr 2:202,265,736...202,303,661 		JBrowse link
G NRP2 neuropilin 2 IAGP ClinVar Annotator: match by term: Primary pulmonary hypertension ClinVar PMID:28492532 PMID:31727138 NCBI chr 2:205,682,501...205,798,131
Ensembl chr 2:205,681,990...205,798,133 		JBrowse link
G PARD3B par-3 family cell polarity regulator beta IAGP ClinVar Annotator: match by term: Primary pulmonary hypertension ClinVar PMID:28492532 PMID:31727138 NCBI chr 2:204,545,475...205,620,162
Ensembl chr 2:204,545,475...205,620,162 		JBrowse link
G PIKFYVE phosphoinositide kinase, FYVE-type zinc finger containing IAGP ClinVar Annotator: match by term: Primary pulmonary hypertension ClinVar PMID:28492532 PMID:31727138 NCBI chr 2:208,266,056...208,358,746
Ensembl chr 2:208,266,255...208,358,746 		JBrowse link
G PLEKHM3 pleckstrin homology domain containing M3 IAGP ClinVar Annotator: match by term: Primary pulmonary hypertension ClinVar PMID:28492532 PMID:31727138 NCBI chr 2:207,821,288...208,025,527
Ensembl chr 2:207,821,288...208,025,527 		JBrowse link
G PPARG peroxisome proliferator activated receptor gamma ISS OMIM:178600 | OMIM:265400 | OMIM:615342 | OMIM:615343 | OMIM:615344 MouseDO NCBI chr 3:12,287,368...12,434,344
Ensembl chr 3:12,287,368...12,434,356 		JBrowse link
G PTGIS prostaglandin I2 synthase IAGP DNA:SNP, missense mutations:intron 4, CDS:c.521+1G>A, p.R252Q (c.755G>A), p.A447T (c.1339G>A) (, rs759344518, rs146531327) (human) RGD PMID:32236489 RGD:401901150 NCBI chr20:49,503,874...49,568,137
Ensembl chr20:49,503,874...49,568,137 		JBrowse link
G PTH2R parathyroid hormone 2 receptor IAGP ClinVar Annotator: match by term: Primary pulmonary hypertension ClinVar PMID:28492532 PMID:31727138 NCBI chr 2:208,359,692...208,494,506
Ensembl chr 2:208,359,714...208,854,503 		JBrowse link
G RAPH1 Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 IAGP ClinVar Annotator: match by term: Primary pulmonary hypertension ClinVar PMID:28492532 PMID:31727138 NCBI chr 2:203,433,682...203,535,301
Ensembl chr 2:203,394,345...203,535,335 		JBrowse link
G RFC1 replication factor C subunit 1 HEP mRNA:increased expression:lung (human) RGD PMID:37410515 RGD:401940160 NCBI chr 4:39,287,456...39,366,362
Ensembl chr 4:39,287,456...39,366,375 		JBrowse link
G RPE ribulose-5-phosphate-3-epimerase IAGP ClinVar Annotator: match by term: Primary pulmonary hypertension ClinVar PMID:28492532 PMID:31727138 NCBI chr 2:210,002,638...210,022,260
Ensembl chr 2:210,002,565...210,022,260 		JBrowse link
G RYR1 ryanodine receptor 1 IDA protein:increased phosphorylation:vastus lateralis RGD PMID:23972212 RGD:329812002 NCBI chr19:38,433,691...38,587,564
Ensembl chr19:38,433,691...38,595,273 		JBrowse link
G SMAD9 SMAD family member 9 EXP
ISS		 CTD Direct Evidence: marker/mechanism
OMIM:178600 | OMIM:265400 | OMIM:615342 | OMIM:615343 | OMIM:615344		 CTD
MouseDO		 NCBI chr13:36,844,831...36,920,854
Ensembl chr13:36,844,831...36,920,887 		JBrowse link
G SOX17 SRY-box transcription factor 17 IEP protein:decreased expression:pulmonary artery (human) RGD PMID:36919784 RGD:329853737 NCBI chr 8:54,457,935...54,460,892
Ensembl chr 8:54,457,935...54,460,892 		JBrowse link
G SUMO1 small ubiquitin like modifier 1 IAGP ClinVar Annotator: match by term: Primary pulmonary hypertension ClinVar PMID:16429395 PMID:16429403 PMID:27453251 PMID:28492532 PMID:29743074 NCBI chr 2:202,206,171...202,238,597
Ensembl chr 2:202,206,182...202,238,599 		JBrowse link
G TNFSF4 TNF superfamily member 4 ISS OMIM:178600 | OMIM:265400 | OMIM:615342 | OMIM:615343 | OMIM:615344 MouseDO NCBI chr 1:173,172,870...173,450,733
Ensembl chr 1:173,162,645...173,477,583 		JBrowse link
G TRIM63 tripartite motif containing 63 IEP mRNA, protein:increased expression:vastus lateralis RGD PMID:23972212 RGD:329812002 NCBI chr 1:26,051,301...26,067,630
Ensembl chr 1:26,051,301...26,068,436 		JBrowse link
G UNC80 unc-80 homolog, NALCN channel complex subunit IAGP ClinVar Annotator: match by term: Primary pulmonary hypertension ClinVar PMID:28492532 PMID:31727138 NCBI chr 2:209,771,832...209,999,296
Ensembl chr 2:209,771,569...209,999,300 		JBrowse link
G VIP vasoactive intestinal peptide ISS OMIM:178600 | OMIM:265400 | OMIM:615342 | OMIM:615343 | OMIM:615344 MouseDO NCBI chr 6:152,750,797...152,759,760
Ensembl chr 6:152,750,797...152,759,765 		JBrowse link
G WDR12 WD repeat domain 12 IAGP ClinVar Annotator: match by term: Primary pulmonary hypertension ClinVar PMID:28492532 PMID:31727138 NCBI chr 2:202,874,261...202,911,673
Ensembl chr 2:202,874,261...203,014,798 		JBrowse link
G ZDBF2 zinc finger DBF-type containing 2 IAGP ClinVar Annotator: match by term: Primary pulmonary hypertension ClinVar PMID:28492532 PMID:31727138 NCBI chr 2:206,274,663...206,314,427
Ensembl chr 2:206,274,663...206,314,427 		JBrowse link
primary pulmonary hypertension 1 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACVRL1 activin A receptor like type 1 IAGP ClinVar Annotator: match by term: Pulmonary hypertension, primary, 1 ClinVar PMID:9245985 PMID:12700602 PMID:14684682 PMID:15024723 PMID:15879500 More... NCBI chr12:51,906,944...51,923,361
Ensembl chr12:51,906,908...51,923,361 		JBrowse link
G AL162586.1 novel transcript IAGP ClinVar Annotator: match by term: Pulmonary hypertension, primary, 1 ClinVar PMID:18498373 PMID:23298310 PMID:24033266 PMID:25741868 PMID:26167679 More... NCBI chr 9:127,816,066...127,822,520
Ensembl chr 9:127,816,066...127,822,520 		JBrowse link
G BMPR2 bone morphogenetic protein receptor type 2 IAGP ClinVar Annotator: match by term: Pulmonary hypertension, primary, 1
ClinVar Annotator: match by term: Pulmonary hypertension, primary, 1, with hereditary hemorrhagic telangiectasia
ClinVar Annotator: match by term: BMPR2-related disorder | ClinVar Annotator: match by term: Pulmonary hypertension, primary, 1		 OMIM
ClinVar		 PMID:3291115 PMID:9536098 PMID:9886286 PMID:10903931 PMID:10973254 More... NCBI chr 2:202,376,327...202,567,749
Ensembl chr 2:202,376,327...202,567,751 		JBrowse link
G ENG endoglin IAGP ClinVar Annotator: match by term: Pulmonary hypertension, primary, 1 ClinVar PMID:16690726 PMID:16754821 PMID:18498373 PMID:23298310 PMID:24033266 More... NCBI chr 9:127,815,016...127,854,658
Ensembl chr 9:127,811,130...127,854,773 		JBrowse link
G KCNA5 potassium voltage-gated channel subfamily A member 5 IAGP ClinVar Annotator: match by term: Pulmonary hypertension, primary, 1 ClinVar PMID:20018952 PMID:21685056 PMID:23861362 PMID:24068186 PMID:25076992 More... NCBI chr12:5,043,879...5,046,788
Ensembl chr12:5,043,879...5,046,788 		JBrowse link
G KCNK3 potassium two pore domain channel subfamily K member 3 IAGP ClinVar Annotator: match by term: Pulmonary hypertension, primary, 1 ClinVar PMID:23883380 NCBI chr 2:26,692,722...26,733,420
Ensembl chr 2:26,692,722...26,733,420 		JBrowse link
G LOC129388983 MPRA-validated peak4014 silencer IAGP ClinVar Annotator: match by term: Pulmonary hypertension, primary, 1 ClinVar PMID:23579436 NCBI chr 2:202,312,153...202,312,353 JBrowse link
G LOC129935429 ATAC-STARR-seq lymphoblastoid active region 16999 IAGP ClinVar Annotator: match by term: Pulmonary hypertension, primary, 1 ClinVar PMID:23579436 NCBI chr 2:202,375,175...202,375,334 JBrowse link
G LOC129935430 ATAC-STARR-seq lymphoblastoid active region 17000 IAGP ClinVar Annotator: match by term: Pulmonary hypertension, primary, 1 ClinVar PMID:23579436 NCBI chr 2:202,375,445...202,375,734 JBrowse link
G LOC129935431 ATAC-STARR-seq lymphoblastoid silent region 12241 IAGP ClinVar Annotator: match by term: Pulmonary hypertension, primary, 1 ClinVar PMID:23579436 NCBI chr 2:202,375,825...202,375,874 JBrowse link
G LOC129935432 ATAC-STARR-seq lymphoblastoid silent region 12242 IAGP ClinVar Annotator: match by term: Pulmonary hypertension, primary, 1 ClinVar PMID:23579436 NCBI chr 2:202,376,025...202,376,514 JBrowse link
G LOC129935433 ATAC-STARR-seq lymphoblastoid silent region 12243 IAGP ClinVar Annotator: match by term: Pulmonary hypertension, primary, 1 ClinVar PMID:23579436 NCBI chr 2:202,376,645...202,376,704 JBrowse link
G LOC129935434 ATAC-STARR-seq lymphoblastoid silent region 12244 IAGP ClinVar Annotator: match by term: Pulmonary hypertension, primary, 1 ClinVar PMID:19223935 PMID:23579436 PMID:25741868 PMID:28492532 NCBI chr 2:202,376,775...202,376,834 JBrowse link
G LOC129935435 ATAC-STARR-seq lymphoblastoid active region 17001 IAGP ClinVar Annotator: match by term: Pulmonary hypertension, primary, 1 ClinVar PMID:11115378 PMID:16429403 PMID:16728714 PMID:18356561 PMID:19555857 More... NCBI chr 2:202,377,675...202,377,744 JBrowse link
G LOC129935436 ATAC-STARR-seq lymphoblastoid silent region 12245 IAGP ClinVar Annotator: match by term: Pulmonary hypertension, primary, 1 ClinVar PMID:16429403 PMID:16728714 PMID:18356561 PMID:20534176 PMID:21737554 More... NCBI chr 2:202,545,681...202,545,750 JBrowse link
G LOC130009576 ATAC-STARR-seq lymphoblastoid silent region 5268 IAGP ClinVar Annotator: match by term: Pulmonary hypertension, primary, 1 ClinVar NCBI chr13:36,920,149...36,920,218 JBrowse link
G NOP58 NOP58 ribonucleoprotein IAGP ClinVar Annotator: match by term: Pulmonary hypertension, primary, 1 ClinVar PMID:23579436 NCBI chr 2:202,265,763...202,303,661
Ensembl chr 2:202,265,736...202,303,661 		JBrowse link
G PAH phenylalanine hydroxylase IAGP ClinVar Annotator: match by term: Pulmonary hypertension, primary, 1 ClinVar PMID:1301187 PMID:1682234 PMID:1769645 PMID:2044609 PMID:2574153 More... NCBI chr12:102,836,889...102,958,441
Ensembl chr12:102,836,889...102,958,410 		JBrowse link
G SMAD1 SMAD family member 1 IAGP ClinVar Annotator: match by term: Pulmonary hypertension, primary, 1 ClinVar PMID:21898662 NCBI chr 4:145,480,770...145,559,176
Ensembl chr 4:145,481,194...145,559,176 		JBrowse link
G SMAD1-AS1 SMAD1 antisense RNA 1 IAGP ClinVar Annotator: match by term: Pulmonary hypertension, primary, 1 ClinVar PMID:21898662 NCBI chr 4:145,514,578...145,517,194
Ensembl chr 4:145,514,615...145,517,118 		JBrowse link
G SMAD4 SMAD family member 4 IAGP ClinVar Annotator: match by term: Pulmonary hypertension, primary, 1 ClinVar PMID:21898662 PMID:24728327 PMID:25502805 PMID:25741868 PMID:28492532 More... NCBI chr18:51,030,213...51,085,042
Ensembl chr18:51,028,528...51,085,045 		JBrowse link
G SMAD9 SMAD family member 9 IAGP ClinVar Annotator: match by term: Pulmonary hypertension, primary, 1 ClinVar PMID:25741868 NCBI chr13:36,844,831...36,920,854
Ensembl chr13:36,844,831...36,920,887 		JBrowse link
G SNORD11 small nucleolar RNA, C/D box 11 IAGP ClinVar Annotator: match by term: Pulmonary hypertension, primary, 1 ClinVar PMID:23579436 NCBI chr 2:202,293,051...202,293,134
Ensembl chr 2:202,293,051...202,293,134 		JBrowse link
G SNORD11B small nucleolar RNA, C/D box 11B IAGP ClinVar Annotator: match by term: Pulmonary hypertension, primary, 1 ClinVar PMID:23579436 NCBI chr 2:202,291,317...202,291,428
Ensembl chr 2:202,291,332...202,291,421 		JBrowse link
G SNORD70 small nucleolar RNA, C/D box 70 IAGP ClinVar Annotator: match by term: Pulmonary hypertension, primary, 1 ClinVar PMID:23579436 NCBI chr 2:202,276,431...202,276,518
Ensembl chr 2:202,276,431...202,276,518 		JBrowse link
G SNORD70B small nucleolar RNA, C/D box 70B IAGP ClinVar Annotator: match by term: Pulmonary hypertension, primary, 1 ClinVar PMID:23579436 NCBI chr 2:202,278,113...202,278,187
Ensembl chr 2:202,278,108...202,278,192 		JBrowse link
G TBX4 T-box transcription factor 4 IAGP ClinVar Annotator: match by term: Pulmonary hypertension, primary, 1 ClinVar PMID:9536098 PMID:15106123 PMID:16199547 PMID:17576681 PMID:23592887 More... NCBI chr17:61,452,422...61,485,110
Ensembl chr17:61,452,404...61,485,110 		JBrowse link
primary pulmonary hypertension 2 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G SMAD9 SMAD family member 9 IAGP ClinVar Annotator: match by term: Pulmonary hypertension, primary, 2 ClinVar
OMIM		 PMID:9536098 PMID:16199547 PMID:17576681 PMID:19211612 PMID:19419974 More... NCBI chr13:36,844,831...36,920,854
Ensembl chr13:36,844,831...36,920,887 		JBrowse link
primary pulmonary hypertension 3 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMPR1B bone morphogenetic protein receptor type 1B IAGP ClinVar Annotator: match by term: Pulmonary hypertension, primary, 3 ClinVar PMID:25741868 PMID:28492532 NCBI chr 4:94,757,955...95,158,450
Ensembl chr 4:94,757,955...95,158,448 		JBrowse link
G CAV1 caveolin 1 IAGP ClinVar Annotator: match by term: Pulmonary hypertension, primary, 3 OMIM
ClinVar		 PMID:22474227 PMID:25741868 PMID:28492532 PMID:29231014 PMID:31727138 NCBI chr 7:116,525,009...116,561,185
Ensembl chr 7:116,524,994...116,561,179 		JBrowse link
G LOC129999168 ATAC-STARR-seq lymphoblastoid silent region 18557 IAGP ClinVar Annotator: match by term: Pulmonary hypertension, primary, 3 ClinVar PMID:28492532 NCBI chr 7:116,526,018...116,526,407 JBrowse link
G LOC129999169 ATAC-STARR-seq lymphoblastoid silent region 18558 IAGP ClinVar Annotator: match by term: Pulmonary hypertension, primary, 3 ClinVar PMID:25741868 PMID:28492532 NCBI chr 7:116,526,638...116,526,737 JBrowse link
primary pulmonary hypertension 4 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G KCNK3 potassium two pore domain channel subfamily K member 3 IAGP ClinVar Annotator: match by term: Pulmonary hypertension, primary, 4 OMIM
ClinVar		 PMID:9536098 PMID:17576681 PMID:23883380 PMID:24033266 PMID:25741868 More... NCBI chr 2:26,692,722...26,733,420
Ensembl chr 2:26,692,722...26,733,420 		JBrowse link
primary pulmonary hypertension 5 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATP13A3 ATPase 13A3 IAGP ClinVar Annotator: match by term: Pulmonary hypertension, primary, autosomal recessive OMIM
ClinVar		 PMID:25741868 PMID:28492532 PMID:30679663 PMID:31727138 PMID:34493544 More... NCBI chr 3:194,402,677...194,494,334
Ensembl chr 3:194,402,672...194,498,364 		JBrowse link
primary pulmonary hypertension 6 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CAPNS1 calpain small subunit 1 IAGP ClinVar Annotator: match by term: Pulmonary hypertension, primary, 6 ClinVar
OMIM		 PMID:21972389 PMID:38230350 NCBI chr19:36,140,066...36,150,353
Ensembl chr19:36,139,953...36,150,353 		JBrowse link
Progressive Renal Failure with Hypertension term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CALCA calcitonin related polypeptide alpha ISO RGD PMID:15928032 RGD:7204486 NCBI chr11:14,966,668...14,972,351
Ensembl chr11:14,966,622...14,972,354 		JBrowse link
Pulmonary Arterial Hypertension term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA3 ATP binding cassette subfamily A member 3 IAGP ClinVar Annotator: match by term: Pulmonary arterial hypertension ClinVar PMID:15976379 PMID:17597647 PMID:18246475 PMID:18317237 PMID:18603241 More... NCBI chr16:2,275,881...2,340,728
Ensembl chr16:2,275,881...2,340,746 		JBrowse link
G ABCC8 ATP binding cassette subfamily C member 8 IAGP ClinVar Annotator: match by term: Pulmonary arterial hypertension ClinVar PMID:25117148 PMID:25741868 NCBI chr11:17,392,498...17,476,845
Ensembl chr11:17,392,498...17,476,894 		JBrowse link
G ABI2 abl interactor 2 IAGP ClinVar Annotator: match by term: Pulmonary arterial hypertension ClinVar PMID:32581362 NCBI chr 2:203,328,394...203,432,169
Ensembl chr 2:203,328,280...203,447,728 		JBrowse link
G ACVRL1 activin A receptor like type 1 IAGP ClinVar Annotator: match by term: Pulmonary arterial hypertension ClinVar PMID:11484689 PMID:15024723 PMID:15517393 PMID:15687131 PMID:16429404 More... NCBI chr12:51,906,944...51,923,361
Ensembl chr12:51,906,908...51,923,361 		JBrowse link
G AHR aryl hydrocarbon receptor severity EXP
IEP		 CTD Direct Evidence: marker/mechanism
protein:increased activity:serum (human)		 CTD
RGD		 PMID:33836606 PMID:33836606 RGD:401940192 NCBI chr 7:17,298,652...17,346,147
Ensembl chr 7:16,916,359...17,346,152 		JBrowse link
G AHSP alpha hemoglobin stabilizing protein IEP mRNA:altered expression: (human) RGD PMID:35710932 RGD:329961295 NCBI chr16:31,527,900...31,528,803
Ensembl chr16:31,527,900...31,528,803 		JBrowse link
G AL162586.1 novel transcript IAGP ClinVar Annotator: match by term: Pulmonary arterial hypertension
ClinVar Annotator: match by term: Pulmonary arterial hypertension associated with congenital heart disease		 ClinVar PMID:18498373 PMID:23298310 PMID:24033266 PMID:25741868 PMID:26167679 More... NCBI chr 9:127,816,066...127,822,520
Ensembl chr 9:127,816,066...127,822,520 		JBrowse link
G ALS2 alsin Rho guanine nucleotide exchange factor ALS2 IAGP ClinVar Annotator: match by term: Pulmonary arterial hypertension ClinVar PMID:32581362 NCBI chr 2:201,700,267...201,780,933
Ensembl chr 2:201,700,267...201,782,112 		JBrowse link
G AOX1 aldehyde oxidase 1 IAGP ClinVar Annotator: match by term: Pulmonary arterial hypertension ClinVar PMID:32581362 NCBI chr 2:200,586,014...200,682,241
Ensembl chr 2:200,586,014...200,677,064 		JBrowse link
G APLN apelin treatment ISO RGD PMID:23867624 RGD:329848996 NCBI chr  X:129,645,259...129,654,956
Ensembl chr  X:129,645,259...129,654,956 		JBrowse link
G ATP13A3 ATPase 13A3 IAGP ClinVar Annotator: match by term: Pulmonary arterial hypertension ClinVar PMID:25741868 PMID:28492532 PMID:30679663 PMID:31727138 PMID:34493544 More... NCBI chr 3:194,402,677...194,494,334
Ensembl chr 3:194,402,672...194,498,364 		JBrowse link
G AXIN2 axin 2 exacerbates ISO RGD PMID:28694128 RGD:151356920 NCBI chr17:65,528,563...65,561,648
Ensembl chr17:65,528,563...65,561,648 		JBrowse link
G BMP7 bone morphogenetic protein 7 ISO protein:increased expression:lung, pulmonary artery (rat) RGD PMID:31542483 RGD:155888480 NCBI chr20:57,168,753...57,266,641
Ensembl chr20:57,168,753...57,266,641 		JBrowse link
G BMPR1A bone morphogenetic protein receptor type 1A IAGP ClinVar Annotator: match by term: Pulmonary arterial hypertension ClinVar PMID:24121792 PMID:25741868 PMID:26467025 PMID:28492532 PMID:30029678 More... NCBI chr10:86,755,763...86,932,844
Ensembl chr10:86,755,786...86,932,825 		JBrowse link
G BMPR1B bone morphogenetic protein receptor type 1B IAGP ClinVar Annotator: match by term: Pulmonary arterial hypertension associated with congenital heart disease ClinVar PMID:25741868 PMID:30029678 NCBI chr 4:94,757,955...95,158,450
Ensembl chr 4:94,757,955...95,158,448 		JBrowse link
G BMPR2 bone morphogenetic protein receptor type 2 treatment IAGP
ISO
EXP		 ClinVar Annotator: match by term: Pulmonary arterial hypertension associated with congenital heart disease
CTD Direct Evidence: marker/mechanism		 ClinVar
CTD
RGD		 PMID:3291115 PMID:9536098 PMID:9886286 PMID:10903931 PMID:10973254 More... RGD:329848996 NCBI chr 2:202,376,327...202,567,749
Ensembl chr 2:202,376,327...202,567,751 		JBrowse link
G BZW1 basic leucine zipper and W2 domains 1 IAGP ClinVar Annotator: match by term: Pulmonary arterial hypertension ClinVar PMID:32581362 NCBI chr 2:200,811,589...200,827,338
Ensembl chr 2:200,810,594...200,827,338 		JBrowse link
G C2CD6 C2 calcium dependent domain containing 6 IAGP ClinVar Annotator: match by term: Pulmonary arterial hypertension ClinVar PMID:32581362 NCBI chr 2:201,487,421...201,619,178
Ensembl chr 2:201,487,421...201,619,178 		JBrowse link
G CARF calcium responsive transcription factor IAGP ClinVar Annotator: match by term: Pulmonary arterial hypertension ClinVar PMID:32581362 NCBI chr 2:202,912,275...202,988,263
Ensembl chr 2:202,912,214...202,988,263 		JBrowse link
G CASP10 caspase 10 IAGP ClinVar Annotator: match by term: Pulmonary arterial hypertension ClinVar PMID:32581362 NCBI chr 2:201,183,141...201,229,406
Ensembl chr 2:201,182,872...201,229,428 		JBrowse link
G CASP8 caspase 8 IAGP ClinVar Annotator: match by term: Pulmonary arterial hypertension ClinVar PMID:32581362 NCBI chr 2:201,233,463...201,287,711
Ensembl chr 2:201,233,443...201,361,836 		JBrowse link
G CAV1 caveolin 1 IAGP ClinVar Annotator: match by term: Pulmonary arterial hypertension associated with congenital heart disease ClinVar PMID:25741868 PMID:30029678 NCBI chr 7:116,525,009...116,561,185
Ensembl chr 7:116,524,994...116,561,179 		JBrowse link
G CD28 CD28 molecule IAGP ClinVar Annotator: match by term: Pulmonary arterial hypertension ClinVar PMID:32581362 NCBI chr 2:203,706,482...203,738,912
Ensembl chr 2:203,706,517...203,739,756 		JBrowse link
G CDH2 cadherin 2 IEP mRNA:increased expression:lung RGD PMID:25593290 RGD:38500244 NCBI chr18:27,932,879...28,177,130
Ensembl chr18:27,932,879...28,177,946 		JBrowse link
G CDK15 cyclin dependent kinase 15 IAGP ClinVar Annotator: match by term: Pulmonary arterial hypertension ClinVar PMID:32581362 NCBI chr 2:201,806,429...201,895,550
Ensembl chr 2:201,790,461...201,895,550 		JBrowse link
G CFLAR CASP8 and FADD like apoptosis regulator IAGP ClinVar Annotator: match by term: Pulmonary arterial hypertension ClinVar PMID:32581362 NCBI chr 2:201,116,164...201,176,687
Ensembl chr 2:201,116,154...201,176,687 		JBrowse link
G CLK1 CDC like kinase 1 IAGP ClinVar Annotator: match by term: Pulmonary arterial hypertension ClinVar PMID:32581362 NCBI chr 2:200,853,009...200,864,658
Ensembl chr 2:200,853,009...200,864,691 		JBrowse link
G CP ceruloplasmin IEP associated with systemic scleroderma;protein:increased expression:serum RGD PMID:32630589 RGD:401827129 NCBI chr 3:149,162,414...149,221,829
Ensembl chr 3:149,162,410...149,221,829 		JBrowse link
G CREB1 cAMP responsive element binding protein 1 treatment ISO RGD PMID:33760143 RGD:401960860 NCBI chr 2:207,529,962...207,605,988
Ensembl chr 2:207,529,737...207,605,988 		JBrowse link
G CTLA4 cytotoxic T-lymphocyte associated protein 4 IAGP ClinVar Annotator: match by term: Pulmonary arterial hypertension ClinVar PMID:32581362 NCBI chr 2:203,867,771...203,873,965
Ensembl chr 2:203,853,888...203,873,965 		JBrowse link
G CTNND1 catenin delta 1 IEP protein:decreased expression:lung RGD PMID:25593290 RGD:38500244 NCBI chr11:57,761,802...57,819,540
Ensembl chr11:57,753,243...57,819,546 		JBrowse link
G CYP20A1 cytochrome P450 family 20 subfamily A member 1 IAGP ClinVar Annotator: match by term: Pulmonary arterial hypertension ClinVar PMID:32581362 NCBI chr 2:203,239,018...203,306,026
Ensembl chr 2:203,238,977...203,306,026 		JBrowse link
G DDAH1 dimethylarginine dimethylaminohydrolase 1 exacerbates ISO compared to wild type RGD PMID:31402164 RGD:151347602 NCBI chr 1:85,318,485...85,578,200
Ensembl chr 1:85,318,481...85,578,363 		JBrowse link
G EIF2AK4 eukaryotic translation initiation factor 2 alpha kinase 4 IAGP ClinVar Annotator: match by term: Pulmonary arterial hypertension ClinVar PMID:25741868 PMID:28492532 PMID:32581362 NCBI chr15:39,934,115...40,035,591
Ensembl chr15:39,934,115...40,035,591 		JBrowse link
G ENG endoglin IAGP ClinVar Annotator: match by term: Pulmonary arterial hypertension
ClinVar Annotator: match by term: Pulmonary arterial hypertension associated with congenital heart disease		 ClinVar PMID:10625079 PMID:15517393 PMID:15521985 PMID:15879500 PMID:16705692 More... NCBI chr 9:127,815,016...127,854,658
Ensembl chr 9:127,811,130...127,854,773 		JBrowse link
G FAM117B family with sequence similarity 117 member B IAGP ClinVar Annotator: match by term: Pulmonary arterial hypertension ClinVar PMID:32581362 NCBI chr 2:202,634,969...202,769,757
Ensembl chr 2:202,634,969...202,769,757 		JBrowse link
G FHIT fragile histidine triad diadenosine triphosphatase ISO RGD PMID:30107138 RGD:329349307 NCBI chr 3:59,747,277...61,251,452
Ensembl chr 3:59,747,277...61,251,459 		JBrowse link
G FLACC1 flagellum associated containing coiled-coil domains 1 IAGP ClinVar Annotator: match by term: Pulmonary arterial hypertension ClinVar PMID:32581362 NCBI chr 2:201,288,271...201,364,289
Ensembl chr 2:201,288,271...201,357,398 		JBrowse link
G FTO FTO alpha-ketoglutarate dependent dioxygenase ISO protein:decreased expression:lung RGD PMID:34310344 RGD:329845886 NCBI chr16:53,703,963...54,121,941
Ensembl chr16:53,701,692...54,158,512 		JBrowse link
G FZD7 frizzled class receptor 7 IAGP ClinVar Annotator: match by term: Pulmonary arterial hypertension ClinVar PMID:32581362 NCBI chr 2:202,033,855...202,038,441
Ensembl chr 2:202,033,855...202,038,441 		JBrowse link
G GDF2 growth differentiation factor 2 IAGP ClinVar Annotator: match by term: Pulmonary arterial hypertension ClinVar PMID:25741868 PMID:26801773 PMID:28492532 PMID:31661308 PMID:31727138 NCBI chr10:47,322,454...47,327,588
Ensembl chr10:47,322,454...47,327,588 		JBrowse link
G GJB2 gap junction protein beta 2 IAGP ClinVar Annotator: match by term: Pulmonary arterial hypertension ClinVar PMID:17666888 PMID:25741868 PMID:30755392 NCBI chr13:20,187,470...20,192,938
Ensembl chr13:20,187,463...20,192,938 		JBrowse link
G GPX3 glutathione peroxidase 3 IEP associated with systemic scleroderma;protein:decreased expression:serum RGD PMID:32630589 RGD:401827129 NCBI chr 5:151,020,591...151,028,988
Ensembl chr 5:151,020,591...151,028,988 		JBrowse link
G H19 H19 imprinted maternally expressed transcript ameliorates
treatment		 ISO RGD PMID:30547791 PMID:30240970 RGD:155882573, RGD:156430315 NCBI chr11:1,995,176...2,001,266
Ensembl chr11:1,995,165...2,004,552 		JBrowse link
G HTR1B 5-hydroxytryptamine receptor 1B IEP protein:increased expression:endothelium, smooth muscle, pulmonary artery RGD PMID:28473438 RGD:329955562 NCBI chr 6:77,460,924...77,463,491
Ensembl chr 6:77,460,924...77,463,491 		JBrowse link
G HYCC2 hyccin PI4KA lipid kinase complex subunit 2 IAGP ClinVar Annotator: match by term: Pulmonary arterial hypertension ClinVar PMID:32581362 NCBI chr 2:200,973,718...201,071,671
Ensembl chr 2:200,973,718...201,071,671 		JBrowse link
G HYDIN HYDIN axonemal central pair apparatus protein IAGP ClinVar Annotator: match by term: Pulmonary arterial hypertension ClinVar PMID:25741868 NCBI chr16:70,802,084...71,230,722
Ensembl chr16:70,802,084...71,230,722 		JBrowse link
G ICA1L islet cell autoantigen 1 like IAGP ClinVar Annotator: match by term: Pulmonary arterial hypertension ClinVar PMID:32581362 NCBI chr 2:202,773,176...202,871,766
Ensembl chr 2:202,773,150...202,871,766 		JBrowse link
G ICOS inducible T cell costimulator IAGP ClinVar Annotator: match by term: Pulmonary arterial hypertension ClinVar PMID:32581362 NCBI chr 2:203,936,763...203,961,577
Ensembl chr 2:203,936,763...203,961,577 		JBrowse link
G IFNG interferon gamma treatment ISO RGD PMID:23867624 RGD:329848996 NCBI chr12:68,154,768...68,159,740
Ensembl chr12:68,154,768...68,159,740 		JBrowse link
G IGF1R insulin like growth factor 1 receptor treatment ISO RGD PMID:30240970 RGD:156430315 NCBI chr15:98,648,539...98,964,530
Ensembl chr15:98,648,539...98,964,530 		JBrowse link
G IL2 interleukin 2 treatment ISO RGD PMID:23867624 RGD:329848996 NCBI chr 4:122,451,470...122,456,725
Ensembl chr 4:122,451,470...122,456,725 		JBrowse link
G IMPA1 inositol monophosphatase 1 ISO RGD PMID:30604625 RGD:126781711 NCBI chr 8:81,656,914...81,686,325
Ensembl chr 8:81,656,914...81,686,331 		JBrowse link
G ITGA5 integrin subunit alpha 5 IEP mRNA:increased expression:lung RGD PMID:25593290 RGD:38500244 NCBI chr12:54,395,261...54,419,266
Ensembl chr12:54,395,261...54,419,266 		JBrowse link
G KCNA5 potassium voltage-gated channel subfamily A member 5 IAGP ClinVar Annotator: match by term: Pulmonary arterial hypertension ClinVar PMID:23861362 PMID:25741868 PMID:28492532 NCBI chr12:5,043,879...5,046,788
Ensembl chr12:5,043,879...5,046,788 		JBrowse link
G KCNK3 potassium two pore domain channel subfamily K member 3 IAGP ClinVar Annotator: match by term: Pulmonary arterial hypertension ClinVar PMID:32581362 NCBI chr 2:26,692,722...26,733,420
Ensembl chr 2:26,692,722...26,733,420 		JBrowse link
G KCNN4 potassium calcium-activated channel subfamily N member 4 ameliorates ISO RGD PMID:28679649 RGD:329955564 NCBI chr19:43,766,533...43,780,973
Ensembl chr19:43,766,533...43,780,976 		JBrowse link
G KCTD18 potassium channel tetramerization domain containing 18 IAGP ClinVar Annotator: match by term: Pulmonary arterial hypertension ClinVar PMID:32581362 NCBI chr 2:200,488,958...200,510,068
Ensembl chr 2:200,488,958...200,519,784 		JBrowse link
G LOC129935429 ATAC-STARR-seq lymphoblastoid active region 16999 IAGP ClinVar Annotator: match by term: Pulmonary arterial hypertension ClinVar PMID:32581362 NCBI chr 2:202,375,175...202,375,334 JBrowse link
G LOC129935430 ATAC-STARR-seq lymphoblastoid active region 17000 IAGP ClinVar Annotator: match by term: Pulmonary arterial hypertension ClinVar PMID:32581362 NCBI chr 2:202,375,445...202,375,734 JBrowse link
G LOC129935431 ATAC-STARR-seq lymphoblastoid silent region 12241 IAGP ClinVar Annotator: match by term: Pulmonary arterial hypertension ClinVar PMID:32581362 NCBI chr 2:202,375,825...202,375,874 JBrowse link
G LOC129935432 ATAC-STARR-seq lymphoblastoid silent region 12242 IAGP ClinVar Annotator: match by term: Pulmonary arterial hypertension ClinVar PMID:32581362 NCBI chr 2:202,376,025...202,376,514 JBrowse link
G LOC129935433 ATAC-STARR-seq lymphoblastoid silent region 12243 IAGP ClinVar Annotator: match by term: Pulmonary arterial hypertension ClinVar PMID:32581362 NCBI chr 2:202,376,645...202,376,704 JBrowse link
G LOC129935434 ATAC-STARR-seq lymphoblastoid silent region 12244 IAGP ClinVar Annotator: match by term: Pulmonary arterial hypertension ClinVar PMID:19223935 PMID:25741868 PMID:28492532 PMID:32581362 NCBI chr 2:202,376,775...202,376,834 JBrowse link
G LOC129935435 ATAC-STARR-seq lymphoblastoid active region 17001 IAGP ClinVar Annotator: match by term: Pulmonary arterial hypertension ClinVar PMID:32581362 NCBI chr 2:202,377,675...202,377,744 JBrowse link
G LOC129935436 ATAC-STARR-seq lymphoblastoid silent region 12245 IAGP ClinVar Annotator: match by term: Pulmonary arterial hypertension ClinVar PMID:32581362 NCBI chr 2:202,545,681...202,545,750 JBrowse link
G MAP3K7 mitogen-activated protein kinase kinase kinase 7 treatment ISO RGD PMID:35582418 RGD:155804297 NCBI chr 6:90,513,579...90,587,072
Ensembl chr 6:90,513,573...90,587,086 		JBrowse link
G MIR140 microRNA 140 severity IEP miRNA:decreased expression:blood (human) RGD PMID:27214554 RGD:329337371 NCBI chr16:69,933,081...69,933,180
Ensembl chr16:69,933,081...69,933,180 		JBrowse link
G MIR143 microRNA 143 ameliorates IEP
ISO		 RNA:increased expression:pulmonary smooth muscle cell: RGD PMID:26311719 PMID:26311719 RGD:11537224, RGD:11537224 NCBI chr 5:149,428,918...149,429,023
Ensembl chr 5:149,428,918...149,429,023 		JBrowse link
G MIR17 microRNA 17 severity IEP miRNA:increased expression:blood RGD PMID:32600075 RGD:329349306 NCBI chr13:91,350,605...91,350,688
Ensembl chr13:91,350,605...91,350,688 		JBrowse link
G MIR200A microRNA 200a treatment ISO RGD PMID:30240970 RGD:156430315 NCBI chr 1:1,167,863...1,167,952
Ensembl chr 1:1,167,863...1,167,952 		JBrowse link
G MIR221 microRNA 221 ameliorates IEP
ISO		 RNA:increased expression:lung,pulmonary artery smooth muscle cell RGD PMID:28694128 PMID:28694128 PMID:28694128 RGD:151356920, RGD:151356920, RGD:151356920 NCBI chr  X:45,746,157...45,746,266
Ensembl chr  X:45,746,157...45,746,266 		JBrowse link
G MIR675 microRNA 675 treatment ISO RGD PMID:30240970 RGD:156430315 NCBI chr11:1,996,759...1,996,831
Ensembl chr11:1,996,759...1,996,831 		JBrowse link
G MPP4 MAGUK p55 scaffold protein 4 IAGP ClinVar Annotator: match by term: Pulmonary arterial hypertension ClinVar PMID:32581362 NCBI chr 2:201,644,874...201,698,644
Ensembl chr 2:201,644,870...201,698,694 		JBrowse link
G NBEAL1 neurobeachin like 1 IAGP ClinVar Annotator: match by term: Pulmonary arterial hypertension ClinVar PMID:32581362 NCBI chr 2:203,014,608...203,225,194
Ensembl chr 2:203,014,608...203,226,378 		JBrowse link
G NDUFB3 NADH:ubiquinone oxidoreductase subunit B3 IAGP ClinVar Annotator: match by term: Pulmonary arterial hypertension ClinVar PMID:32581362 NCBI chr 2:201,072,001...201,085,750
Ensembl chr 2:201,071,433...201,085,750 		JBrowse link
G NIF3L1 NGG1 interacting factor 3 like 1 IAGP ClinVar Annotator: match by term: Pulmonary arterial hypertension ClinVar PMID:32581362 NCBI chr 2:200,889,327...200,903,932
Ensembl chr 2:200,889,327...200,903,938 		JBrowse link
G NNMT nicotinamide N-methyltransferase ISO protein:increased activity,altered activity:lung, liver (rat) RGD PMID:27581040 RGD:401793717 NCBI chr11:114,257,806...114,313,536
Ensembl chr11:114,257,787...114,313,536 		JBrowse link
G NOP58 NOP58 ribonucleoprotein IAGP ClinVar Annotator: match by term: Pulmonary arterial hypertension ClinVar PMID:32581362 NCBI chr 2:202,265,763...202,303,661
Ensembl chr 2:202,265,736...202,303,661 		JBrowse link
G NOS3 nitric oxide synthase 3 treatment ISO RGD PMID:23867624 RGD:329848996 NCBI chr 7:150,991,017...151,014,588
Ensembl chr 7:150,991,017...151,014,588 		JBrowse link
G NOTCH1 notch receptor 1 IAGP
IEP		 ClinVar Annotator: match by term: Pulmonary arterial hypertension
protein:decreased expression:endothelial cell, nucleus:		 ClinVar
RGD		 PMID:15472075 PMID:16614245 PMID:18593716 PMID:19245433 PMID:19635999 More... RGD:155646132 NCBI chr 9:136,494,433...136,546,048
Ensembl chr 9:136,494,433...136,546,048 		JBrowse link
G NOTCH3 notch receptor 3 IAGP ClinVar Annotator: match by term: Pulmonary arterial hypertension ClinVar PMID:22006983 PMID:22153900 PMID:22159056 PMID:24086431 PMID:25741868 More... NCBI chr19:15,159,038...15,200,995
Ensembl chr19:15,159,038...15,200,995 		JBrowse link
G ORC2 origin recognition complex subunit 2 IAGP ClinVar Annotator: match by term: Pulmonary arterial hypertension ClinVar PMID:32581362 NCBI chr 2:200,908,977...200,963,660
Ensembl chr 2:200,908,977...200,963,680 		JBrowse link
G PARK7 Parkinsonism associated deglycase exacerbates ISO RGD PMID:29069575 RGD:151347449 NCBI chr 1:7,961,711...7,985,505
Ensembl chr 1:7,954,291...7,985,505 		JBrowse link
G PDCD4 programmed cell death 4 treatment ISO RGD PMID:30240970 RGD:156430315 NCBI chr10:110,871,928...110,900,006
Ensembl chr10:110,871,795...110,900,006 		JBrowse link
G PHF6 PHD finger protein 6 IAGP ClinVar Annotator: match by term: Pulmonary arterial hypertension ClinVar PMID:25741868 NCBI chr  X:134,373,312...134,428,790
Ensembl chr  X:134,373,288...134,428,791 		JBrowse link
G PMS2 PMS1 homolog 2, mismatch repair system component IAGP ClinVar Annotator: match by term: Pulmonary arterial hypertension ClinVar PMID:6144131 PMID:16144131 PMID:16283678 PMID:18602922 PMID:19283792 More... NCBI chr 7:5,970,925...6,009,106
Ensembl chr 7:5,970,925...6,009,130 		JBrowse link
G PPIL3 peptidylprolyl isomerase like 3 IAGP ClinVar Annotator: match by term: Pulmonary arterial hypertension ClinVar PMID:32581362 NCBI chr 2:200,870,907...200,889,291
Ensembl chr 2:200,870,907...200,889,303 		JBrowse link
G PTGIS prostaglandin I2 synthase treatment
susceptibility		 IMP
IAGP
ISO		 human gene in a rat model
DNA:repeat, SNPs:promoter, intron: , 185C>T, 325C>A ( , rs5582, rs116939356) (human)		 RGD PMID:17635855 PMID:23841984 PMID:24605778 PMID:11034952 PMID:18612919 RGD:401901195, RGD:401959742, RGD:401959406, RGD:401959335, RGD:401901264 NCBI chr20:49,503,874...49,568,137
Ensembl chr20:49,503,874...49,568,137 		JBrowse link
G PTPRD protein tyrosine phosphatase receptor type D IEP mRNA:decreased expression:blood, pulmonary artery (human) RGD PMID:35848503 RGD:401976433 NCBI chr 9:8,314,246...10,613,002
Ensembl chr 9:8,314,246...10,613,002 		JBrowse link
G RAPH1 Ras association (RalGDS/AF-6) and pleckstrin homology domains 1 IAGP ClinVar Annotator: match by term: Pulmonary arterial hypertension ClinVar PMID:32581362 NCBI chr 2:203,433,682...203,535,301
Ensembl chr 2:203,394,345...203,535,335 		JBrowse link
G SELENOP selenoprotein P IEP associated with systemic scleroderma;protein:decreased expression:serum RGD PMID:32630589 RGD:401827129 NCBI chr 5:42,799,880...42,811,892
Ensembl chr 5:42,799,880...42,887,392 		JBrowse link
G SGO2 shugoshin 2 IAGP ClinVar Annotator: match by term: Pulmonary arterial hypertension ClinVar PMID:32581362 NCBI chr 2:200,526,142...200,584,096
Ensembl chr 2:200,510,008...200,584,096 		JBrowse link
G SMAD4 SMAD family member 4 IAGP ClinVar Annotator: match by term: Pulmonary arterial hypertension ClinVar PMID:25559809 PMID:25741868 PMID:26467025 PMID:28492532 PMID:29684080 NCBI chr18:51,030,213...51,085,042
Ensembl chr18:51,028,528...51,085,045 		JBrowse link
G SMAD9 SMAD family member 9 IAGP ClinVar Annotator: match by term: Pulmonary arterial hypertension associated with congenital heart disease ClinVar PMID:25741868 PMID:28492532 PMID:30029678 NCBI chr13:36,844,831...36,920,854
Ensembl chr13:36,844,831...36,920,887 		JBrowse link
G SOD2 superoxide dismutase 2 ISO
IEP		 protein:decreased expression:pulmonary artery
protein:decreased expression:small pulmonary artery		 RGD PMID:20529999 PMID:20529999 RGD:27095884, RGD:27095884 NCBI chr 6:159,669,069...159,762,281
Ensembl chr 6:159,669,069...159,762,529 		JBrowse link
G SOD3 superoxide dismutase 3 exacerbates ISO RGD PMID:21730301 RGD:14369425 NCBI chr 4:24,795,573...24,800,842
Ensembl chr 4:24,789,912...24,800,842 		JBrowse link
G SOX17 SRY-box transcription factor 17 susceptibility
onset		 IAGP
IEP		 ClinVar Annotator: match by term: Pulmonary arterial hypertension
DNA:SNPs:enhancers: (rs10103692, rs13266183) (human)
DNA:frameshift mutations, missense mutations, SNP:CDS, intron:multiple (human)
DNA:nonsense mutation:CDS:p.Q127* (human)
protein:decreased expression:lung endothelium (human)
associated with congenital heart disease;DNA:mutations:multiple (human)		 ClinVar
RGD		 PMID:30527955 PMID:29650961 PMID:33952808 PMID:36913491 PMID:30029678 RGD:329955464, RGD:329853735, RGD:329853326, RGD:329853317, RGD:329853313 NCBI chr 8:54,457,935...54,460,892
Ensembl chr 8:54,457,935...54,460,892 		JBrowse link
G SPATS2L spermatogenesis associated serine rich 2 like IAGP ClinVar Annotator: match by term: Pulmonary arterial hypertension ClinVar PMID:32581362 NCBI chr 2:200,305,879...200,482,264
Ensembl chr 2:200,305,881...200,482,264 		JBrowse link
G STRADB STE20 related adaptor beta IAGP ClinVar Annotator: match by term: Pulmonary arterial hypertension ClinVar PMID:32581362 NCBI chr 2:201,451,740...201,480,846
Ensembl chr 2:201,387,858...201,480,846 		JBrowse link
G SUMO1 small ubiquitin like modifier 1 IAGP ClinVar Annotator: match by term: Pulmonary arterial hypertension ClinVar PMID:32581362 NCBI chr 2:202,206,171...202,238,597
Ensembl chr 2:202,206,182...202,238,599 		JBrowse link
G TBX4 T-box transcription factor 4 IAGP ClinVar Annotator: match by term: Pulmonary arterial hypertension associated with congenital heart disease ClinVar PMID:15106123 PMID:16199547 PMID:23592887 PMID:25741868 PMID:28492532 More... NCBI chr17:61,452,422...61,485,110
Ensembl chr17:61,452,404...61,485,110 		JBrowse link
G TGFBR1 transforming growth factor beta receptor 1 IEP mRNA:increased expression:lung RGD PMID:25593290 RGD:38500244 NCBI chr 9:99,103,647...99,154,192
Ensembl chr 9:99,104,038...99,154,192 		JBrowse link
G TMEM237 transmembrane protein 237 IAGP ClinVar Annotator: match by term: Pulmonary arterial hypertension ClinVar PMID:32581362 NCBI chr 2:201,620,186...201,643,503
Ensembl chr 2:201,620,184...201,643,570 		JBrowse link
G TOPBP1 DNA topoisomerase II binding protein 1 IAGP ClinVar Annotator: match by term: Pulmonary arterial hypertension ClinVar PMID:25741868 NCBI chr 3:133,600,238...133,661,941
Ensembl chr 3:133,598,175...133,662,380 		JBrowse link
G TRAK2 trafficking kinesin protein 2 IAGP ClinVar Annotator: match by term: Pulmonary arterial hypertension ClinVar PMID:32581362 NCBI chr 2:201,377,207...201,451,458
Ensembl chr 2:201,377,207...201,451,500 		JBrowse link
G TRPC4 transient receptor potential cation channel subfamily C member 4 ameliorates ISO RGD PMID:24113457 RGD:150429956 NCBI chr13:37,632,063...37,869,772
Ensembl chr13:37,632,063...37,869,802 		JBrowse link
G TWIST1 twist family bHLH transcription factor 1 IEP mRNA, protein:increased expression: pulmonary artery,lung: RGD PMID:25593290 RGD:38500244 NCBI chr 7:19,113,047...19,117,636
Ensembl chr 7:19,020,991...19,117,636 		JBrowse link
G VIM vimentin IEP protein:increased phosphorylation:lung RGD PMID:25593290 RGD:38500244 NCBI chr10:17,228,241...17,237,593
Ensembl chr10:17,228,241...17,237,593 		JBrowse link
G WDR12 WD repeat domain 12 IAGP ClinVar Annotator: match by term: Pulmonary arterial hypertension ClinVar PMID:32581362 NCBI chr 2:202,874,261...202,911,673
Ensembl chr 2:202,874,261...203,014,798 		JBrowse link
Pulmonary Arterial Hypertension, Hereditary Hemorrhagic Telangiectasia-Related term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACVRL1 activin A receptor like type 1 IAGP ClinVar Annotator: match by term: PULMONARY ARTERIAL HYPERTENSION, HEREDITARY HEMORRHAGIC TELANGIECTASIA-RELATED ClinVar PMID:8640225 PMID:9245985 PMID:10187774 PMID:10767348 PMID:11170071 More... NCBI chr12:51,906,944...51,923,361
Ensembl chr12:51,906,908...51,923,361 		JBrowse link
G AL162586.1 novel transcript IAGP ClinVar Annotator: match by term: PULMONARY ARTERIAL HYPERTENSION, HEREDITARY HEMORRHAGIC TELANGIECTASIA-RELATED ClinVar PMID:14684682 PMID:15024723 PMID:15115879 PMID:15687131 PMID:15879500 More... NCBI chr 9:127,816,066...127,822,520
Ensembl chr 9:127,816,066...127,822,520 		JBrowse link
G ENG endoglin IAGP ClinVar Annotator: match by term: PULMONARY ARTERIAL HYPERTENSION, HEREDITARY HEMORRHAGIC TELANGIECTASIA-RELATED ClinVar PMID:14684682 PMID:15024723 PMID:15115879 PMID:15687131 PMID:15879500 More... NCBI chr 9:127,815,016...127,854,658
Ensembl chr 9:127,811,130...127,854,773 		JBrowse link
Pulmonary Edema of Mountaineers term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G DNM1L dynamin 1 like ISO mRNA:increased expression:lung (rat) RGD PMID:23517027 RGD:12738217 NCBI chr12:32,679,301...32,745,650
Ensembl chr12:32,679,200...32,745,650 		JBrowse link
G FIS1 fission, mitochondrial 1 ISO mRNA:increased expression:lung (rat) RGD PMID:23517027 RGD:12738217 NCBI chr 7:101,239,472...101,245,081
Ensembl chr 7:101,239,458...101,252,316 		JBrowse link
G GUCY1A1 guanylate cyclase 1 soluble subunit alpha 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:25373139 NCBI chr 4:155,666,848...155,737,059
Ensembl chr 4:155,666,726...155,737,059 		JBrowse link
G HMOX1 heme oxygenase 1 ISO protein:increased expression:lung RGD PMID:21296072 RGD:10755745 NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214 		JBrowse link
G MFN2 mitofusin 2 ISO mRNA:decreased expression:lung (rat) RGD PMID:23517027 RGD:12738217 NCBI chr 1:11,980,444...12,013,508
Ensembl chr 1:11,980,181...12,015,211 		JBrowse link
pulmonary hypertension term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ABCA3 ATP binding cassette subfamily A member 3 EXP CTD Direct Evidence: marker/mechanism CTD PMID:26780485 NCBI chr16:2,275,881...2,340,728
Ensembl chr16:2,275,881...2,340,746 		JBrowse link
G ACE angiotensin I converting enzyme EXP CTD Direct Evidence: marker/mechanism CTD PMID:12359135 NCBI chr17:63,477,061...63,498,373
Ensembl chr17:63,477,061...63,498,380 		JBrowse link
G ACE2 angiotensin converting enzyme 2 treatment EXP
IMP		 CTD Direct Evidence: therapeutic
human protein in a rat model		 CTD
RGD		 PMID:31931441 PMID:25225206 RGD:40818280 NCBI chr  X:15,518,197...15,607,211
Ensembl chr  X:15,494,566...15,607,236 		JBrowse link
G ACVRL1 activin A receptor like type 1 susceptibility
disease_progression		 IAGP
EXP
ISO		 associated with hereditary haemorrhagic telangiectasia;DNA:missense mutations
CTD Direct Evidence: marker/mechanism
DNA:mutations (human)
mRNA:increased expression:lung		 CTD
RGD		 PMID:26540443 PMID:14684682 PMID:20056902 PMID:17392319 RGD:1601117, RGD:5128837, RGD:1601116 NCBI chr12:51,906,944...51,923,361
Ensembl chr12:51,906,908...51,923,361 		JBrowse link
G ADH5 alcohol dehydrogenase 5 (class III), chi polypeptide ISO RGD PMID:20431245 RGD:5128886 NCBI chr 4:99,070,978...99,088,788
Ensembl chr 4:99,070,978...99,088,801 		JBrowse link
G ADIPOQ adiponectin, C1Q and collagen domain containing ISO RGD PMID:19168697 RGD:5686821 NCBI chr 3:186,842,710...186,858,463
Ensembl chr 3:186,842,704...186,858,463 		JBrowse link
G ADM adrenomedullin IDA RGD PMID:14718403 RGD:1625305 NCBI chr11:10,305,073...10,307,397
Ensembl chr11:10,305,073...10,307,397 		JBrowse link
G AGER advanced glycosylation end-product specific receptor IEP protein:increased expression:lung (human) RGD PMID:21041689 RGD:7244258 NCBI chr 6:32,180,969...32,184,253
Ensembl chr 6:32,180,968...32,184,322 		JBrowse link
G AGT angiotensinogen ISO RGD PMID:21381494 RGD:5129162 NCBI chr 1:230,702,523...230,745,583
Ensembl chr 1:230,690,776...230,745,576 		JBrowse link
G AGTR1 angiotensin II receptor type 1 onset IAGP DNA:polymorphism:3' utr:1166A>C (human) RGD PMID:19332265 RGD:5147450 NCBI chr 3:148,697,903...148,743,003
Ensembl chr 3:148,697,784...148,743,008 		JBrowse link
G AHR aryl hydrocarbon receptor ameliorates ISO 6-formylindolo[3,2-b]carbazole (FICZ)|semaxanib (CHEBI:91083)
compared to wild type littermates		 RGD PMID:33836606 PMID:33836606 RGD:401940192, RGD:401940192 NCBI chr 7:17,298,652...17,346,147
Ensembl chr 7:16,916,359...17,346,152 		JBrowse link
G ALAS1 5'-aminolevulinate synthase 1 ISO mRNA:increased expression:lung (rat) RGD PMID:16181105 RGD:4144185 NCBI chr 3:52,198,083...52,214,327
Ensembl chr 3:52,198,086...52,214,327 		JBrowse link
G ALOX5 arachidonate 5-lipoxygenase treatment IEP
IGI
ISO
EXP		 protein:increased expression:artery
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:14726295 PMID:9445303 PMID:31462075 PMID:31462075 PMID:31462075 More... RGD:1626154, RGD:14975304, RGD:14975304, RGD:14975304, RGD:14975304, RGD:734558, RGD:4890418 NCBI chr10:45,374,216...45,446,117
Ensembl chr10:45,374,176...45,446,119 		JBrowse link
G ALOX5AP arachidonate 5-lipoxygenase activating protein IEP
ISO		 protein:increased expression:artery RGD PMID:9445303 PMID:8647941 RGD:1626154, RGD:734558 NCBI chr13:30,713,485...30,764,426
Ensembl chr13:30,713,478...30,764,426 		JBrowse link
G ANGPT1 angiopoietin 1 ISO protein:decreased expression:pulmonary artery RGD PMID:18073453 RGD:2316069 NCBI chr 8:107,249,482...107,497,918
Ensembl chr 8:107,249,482...107,498,055 		JBrowse link
G ANGPT2 angiopoietin 2 ISO protein:increased expression:pulmonary artery (rat) RGD PMID:19712575 RGD:2314185 NCBI chr 8:6,499,632...6,563,245
Ensembl chr 8:6,499,632...6,563,409 		JBrowse link
G APLN apelin IEP protein:decreased expression:plasma RGD PMID:16263185 RGD:1626175 NCBI chr  X:129,645,259...129,654,956
Ensembl chr  X:129,645,259...129,654,956 		JBrowse link
G ARG2 arginase 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:24951775 NCBI chr14:67,619,920...67,651,708
Ensembl chr14:67,619,920...67,651,708 		JBrowse link
G ATP2A2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 treatment ISO
IDA		 RGD PMID:27144451 PMID:23804254 RGD:13782086, RGD:13782089 NCBI chr12:110,280,616...110,351,093
Ensembl chr12:110,280,756...110,351,093 		JBrowse link
G ATP5F1A ATP synthase F1 subunit alpha treatment ISO chronic thromboembolic pulmonary hypertension RGD PMID:21396162 RGD:13703061 NCBI chr18:46,080,248...46,104,227
Ensembl chr18:46,080,248...46,104,334 		JBrowse link
G ATP5PF ATP synthase peripheral stalk subunit F6 treatment ISO mRNA, protein:increased expression:lung, plasma (rat) RGD PMID:27916219 PMID:27491388 RGD:13800892, RGD:13800894 NCBI chr21:25,724,500...25,735,653
Ensembl chr21:25,716,503...25,735,673 		JBrowse link
G ATP7A ATPase copper transporting alpha EXP CTD Direct Evidence: marker/mechanism CTD PMID:24614111 NCBI chr  X:77,910,693...78,050,395
Ensembl chr  X:77,910,690...78,050,395 		JBrowse link
G BCL2 BCL2 apoptosis regulator ISO protein:decreased expression:heart right ventricle RGD PMID:18441466 RGD:2293022 NCBI chr18:63,123,346...63,320,090
Ensembl chr18:63,123,346...63,320,128 		JBrowse link
G BCL2L1 BCL2 like 1 treatment ISO RGD PMID:22559233 RGD:10400914 NCBI chr20:31,664,452...31,723,963
Ensembl chr20:31,664,452...31,723,989 		JBrowse link
G BDKRB2 bradykinin receptor B2 ISO RGD PMID:15878794 RGD:4890453 NCBI chr14:96,204,839...96,244,164
Ensembl chr14:96,204,679...96,244,166 		JBrowse link
G BIRC5 baculoviral IAP repeat containing 5 IEP
ISO		 protein:increased expression:pulmonary artery RGD PMID:15931388 PMID:15931388 RGD:2293135, RGD:2293135 NCBI chr17:78,214,253...78,225,635
Ensembl chr17:78,214,186...78,225,636 		JBrowse link
G BMPR1A bone morphogenetic protein receptor type 1A IEP RGD PMID:19324947 RGD:5129472 NCBI chr10:86,755,763...86,932,844
Ensembl chr10:86,755,786...86,932,825 		JBrowse link
G BMPR1B bone morphogenetic protein receptor type 1B IEP RGD PMID:19324947 RGD:5129472 NCBI chr 4:94,757,955...95,158,450
Ensembl chr 4:94,757,955...95,158,448 		JBrowse link
G BMPR2 bone morphogenetic protein receptor type 2 disease_progression
treatment		 IAGP
ISO
IDA
EXP
IEP		 DNA:missense mutations (human)
induced by human ad-ALOX5
protein:decreased expression:lung
CTD Direct Evidence: marker/mechanism
DNA:mutations: :multiple (human)		 CTD
RGD		 PMID:11590841 PMID:11893684 PMID:12358323 PMID:16297860 PMID:20496075 More... RGD:5129239, RGD:14975304, RGD:38500243, RGD:38500244, RGD:5129474, RGD:5129472, RGD:1580076, RGD:5129238, RGD:5129237 NCBI chr 2:202,376,327...202,567,749
Ensembl chr 2:202,376,327...202,567,751 		JBrowse link
G BRD4 bromodomain containing 4 EXP CTD Direct Evidence: therapeutic CTD PMID:26224795 NCBI chr19:15,235,519...15,332,539
Ensembl chr19:15,235,519...15,332,545 		JBrowse link
G CA9 carbonic anhydrase 9 EXP CTD Direct Evidence: marker/mechanism CTD PMID:20110409 NCBI chr 9:35,673,928...35,681,159
Ensembl chr 9:35,673,928...35,681,159 		JBrowse link
G CALCA calcitonin related polypeptide alpha EXP CTD Direct Evidence: therapeutic CTD PMID:1357980 NCBI chr11:14,966,668...14,972,351
Ensembl chr11:14,966,622...14,972,354 		JBrowse link
G CASR calcium sensing receptor ISO protein:increased expression:pulmonary artery (rat) RGD PMID:22730443 RGD:7205669 NCBI chr 3:122,183,668...122,291,629
Ensembl chr 3:122,183,668...122,291,629 		JBrowse link
G CAV1 caveolin 1 treatment IEP
ISO		 idiopathic pulmonary arterial hypertension (IPAH) RGD PMID:17470567 PMID:23538027 PMID:15353500 RGD:1625360, RGD:8662276, RGD:1581153 NCBI chr 7:116,525,009...116,561,185
Ensembl chr 7:116,524,994...116,561,179 		JBrowse link
G CAVIN1 caveolae associated protein 1 ISS OMIM:615371 MouseDO NCBI chr17:42,402,449...42,423,256
Ensembl chr17:42,402,449...42,423,256 		JBrowse link
G CBLN2 cerebellin 2 precursor EXP CTD Direct Evidence: marker/mechanism CTD PMID:23502781 NCBI chr18:72,536,681...72,638,521
Ensembl chr18:72,536,680...72,638,521 		JBrowse link
G CCL1 C-C motif chemokine ligand 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:22507635 NCBI chr17:34,360,328...34,363,233
Ensembl chr17:34,360,328...34,363,233 		JBrowse link
G CCL2 C-C motif chemokine ligand 2 ISO
EXP		 protein:increased expression:lung, plasma
CTD Direct Evidence: marker/mechanism
protein:increased expression:bronchoalveolar lavage fluid (rat)		 CTD
RGD		 PMID:15302794 PMID:30418988 PMID:19087668 PMID:9605182 RGD:2307003, RGD:8549547 NCBI chr17:34,255,285...34,257,203
Ensembl chr17:34,255,274...34,257,208 		JBrowse link
G CCL5 C-C motif chemokine ligand 5 IEP protein:increased secretion:serum (human) RGD PMID:19932032 RGD:4891440 NCBI chr17:35,871,491...35,880,360
Ensembl chr17:35,871,491...35,880,793 		JBrowse link
G CCN2 cellular communication network factor 2 ISO protein:increased expression:pulmonary artery (rat) RGD PMID:19234054 RGD:2314535 NCBI chr 6:131,948,176...131,951,372
Ensembl chr 6:131,948,176...131,951,372 		JBrowse link
G CD209 CD209 molecule IEP RGD PMID:17107989 RGD:5131187 NCBI chr19:7,739,993...7,747,534
Ensembl chr19:7,739,993...7,747,564 		JBrowse link
G CD28 CD28 molecule IEP RGD PMID:19075187 RGD:5131619 NCBI chr 2:203,706,482...203,738,912
Ensembl chr 2:203,706,517...203,739,756 		JBrowse link
G CD40 CD40 molecule treatment ISO RGD PMID:25998782 RGD:11344970 NCBI chr20:46,118,314...46,129,858
Ensembl chr20:46,118,271...46,129,863 		JBrowse link
G CD40LG CD40 ligand ISO
EXP		 protein:increased expression:serum (rat)
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:15302794 PMID:25998782 RGD:11344970 NCBI chr  X:136,648,158...136,660,390
Ensembl chr  X:136,648,158...136,660,390 		JBrowse link
G CD86 CD86 molecule IEP protein:decreased expression:blood, myeloid dendritic cell (human) RGD PMID:19693657 RGD:4892293 NCBI chr 3:122,055,362...122,121,136
Ensembl chr 3:122,055,362...122,121,139 		JBrowse link
G CDH5 cadherin 5 ISO protein:decreased expression:lung RGD PMID:25593290 RGD:38500244 NCBI chr16:66,366,691...66,404,784
Ensembl chr16:66,366,690...66,404,784 		JBrowse link
G CDKN1A cyclin dependent kinase inhibitor 1A treatment ISO RGD PMID:24334871 PMID:24412385 RGD:10043360, RGD:10043361 NCBI chr 6:36,676,463...36,687,332
Ensembl chr 6:36,676,460...36,687,397 		JBrowse link
G CDKN1B cyclin dependent kinase inhibitor 1B treatment ISO RGD PMID:22383500 RGD:10045357 NCBI chr12:12,717,368...12,722,369
Ensembl chr12:12,685,498...12,722,369 		JBrowse link
G CLU clusterin ISO RGD PMID:25069740 RGD:9068424 NCBI chr 8:27,596,917...27,614,700
Ensembl chr 8:27,596,917...27,614,700 		JBrowse link
G COL1A1 collagen type I alpha 1 chain treatment ISO RGD PMID:25867313 RGD:11041577 NCBI chr17:50,184,101...50,201,631
Ensembl chr17:50,184,101...50,201,632 		JBrowse link
G COL4A1 collagen type IV alpha 1 chain treatment ISO RGD PMID:25867313 RGD:11041577 NCBI chr13:110,148,963...110,307,157
Ensembl chr13:110,148,963...110,307,202 		JBrowse link
G CRP C-reactive protein IEP associated with Pulmonary Disease, Chronic Obstructive RGD PMID:22333502 RGD:6482312 NCBI chr 1:159,712,289...159,714,589
Ensembl chr 1:159,712,289...159,714,589 		JBrowse link
G CSF3 colony stimulating factor 3 treatment IDA RGD PMID:17186992 PMID:12524378 RGD:11039432, RGD:11039539 NCBI chr17:40,015,440...40,017,813
Ensembl chr17:40,015,361...40,017,813 		JBrowse link
G CTNND1 catenin delta 1 treatment ISO RGD PMID:25593290 RGD:38500244 NCBI chr11:57,761,802...57,819,540
Ensembl chr11:57,753,243...57,819,546 		JBrowse link
G CX3CL1 C-X3-C motif chemokine ligand 1 ISO
IEP		 mRNA, protein:increased expression:lung
associated with Heart Defects, Congenital		 RGD PMID:18630689 PMID:19948918 PMID:20869263 RGD:4891889, RGD:4891887, RGD:4891883 NCBI chr16:57,372,490...57,385,044
Ensembl chr16:57,372,477...57,385,044 		JBrowse link
G CX3CR1 C-X3-C motif chemokine receptor 1 ISO
IAGP		 mRNA, protein:increased expression:lung
associated with Scleroderma, Systemic;DNA:polymorphisms: :p.V249I, p.T280M (human)		 RGD PMID:17182651 PMID:16584113 RGD:4891893, RGD:4891896 NCBI chr 3:39,263,494...39,292,966
Ensembl chr 3:39,263,495...39,281,735 		JBrowse link
G CXCL8 C-X-C motif chemokine ligand 8 EXP CTD Direct Evidence: marker/mechanism CTD PMID:15302794 NCBI chr 4:73,740,569...73,743,716
Ensembl chr 4:73,740,519...73,743,716 		JBrowse link
G CXCR4 C-X-C motif chemokine receptor 4 treatment ISO RGD PMID:21294880 RGD:6480473 NCBI chr 2:136,114,349...136,118,149
Ensembl chr 2:136,114,349...136,119,177 		JBrowse link
G CYBA cytochrome b-245 alpha chain ISO associated with Anoxia;mRNA, protein:increased expression:lung RGD PMID:18424632 PMID:18952568 RGD:4773907, RGD:4762683 NCBI chr16:88,643,289...88,651,053
Ensembl chr16:88,643,275...88,651,083 		JBrowse link
G CYBB cytochrome b-245 beta chain treatment ISO associated with Anoxia RGD PMID:18952568 PMID:18424632 RGD:4762683, RGD:4773907 NCBI chr  X:37,780,059...37,813,461
Ensembl chr  X:37,780,018...37,813,461 		JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 ISO mRNA,protein:increased expression:lung RGD PMID:28956952 RGD:13702097 NCBI chr15:74,719,542...74,725,528
Ensembl chr15:74,719,542...74,725,536 		JBrowse link
G CYP2J2 cytochrome P450 family 2 subfamily J member 2 IDA RGD PMID:20118222 RGD:7243137 NCBI chr 1:59,893,308...59,969,212
Ensembl chr 1:59,893,308...59,926,773 		JBrowse link
G CYSLTR1 cysteinyl leukotriene receptor 1 ISO associated with Anoxia RGD PMID:12910720 RGD:4848274 NCBI chr  X:78,271,468...78,327,611
Ensembl chr  X:78,271,468...78,327,691 		JBrowse link
G DLL4 delta like canonical Notch ligand 4 ISO RGD PMID:34739767 RGD:155646132 NCBI chr15:40,929,340...40,939,073
Ensembl chr15:40,929,340...40,939,073 		JBrowse link
G ECE1 endothelin converting enzyme 1 ISO associated with Anoxia; RGD PMID:18767389 RGD:7243939 NCBI chr 1:21,217,250...21,345,504
Ensembl chr 1:21,217,247...21,345,572 		JBrowse link
G EDN1 endothelin 1 IEP
EXP
ISO		 associated with Pulmonary Disease, Chronic Obstructive; protein:increased secretion:plasma (human)
CTD Direct Evidence: marker/mechanism
mRNA:increased expression:lung (rat)
Hypertension, Portopulmonary; protein:increased secretion:plasma (human)
Hypertension, Heritable Pulmonary Artery; mRNA:increased expression:bone marrow, macrophage (mouse)		 CTD
RGD		 PMID:7549228 PMID:9918753 PMID:12391278 PMID:20929026 PMID:20967148 More... RGD:4144865, RGD:4144128, RGD:4144882, RGD:4144877 NCBI chr 6:12,230,516...12,297,194
Ensembl chr 6:12,290,361...12,297,194 		JBrowse link
G EDN2 endothelin 2 IEP RGD PMID:10598486 RGD:1580918 NCBI chr 1:41,478,775...41,484,683
Ensembl chr 1:41,478,775...41,484,683 		JBrowse link
G EDNRA endothelin receptor type A ISO
IMP
IEP		 RGD PMID:20531217 PMID:15243299 PMID:18506008 PMID:20562228 RGD:4892283, RGD:1580949, RGD:4892320, RGD:4144877 NCBI chr 4:147,481,097...147,544,954
Ensembl chr 4:147,480,917...147,544,954 		JBrowse link
G EDNRB endothelin receptor type B IEP
EXP
ISO		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:15927975 PMID:20562228 PMID:15243299 PMID:18091567 RGD:4144877, RGD:1580949, RGD:4892289 NCBI chr13:77,895,487...77,975,527
Ensembl chr13:77,895,481...77,975,529 		JBrowse link
G EGFR epidermal growth factor receptor ISO
IEP		 protein:increased expression:lung, arteriole (human) RGD PMID:12896876 PMID:21492463 RGD:5131639, RGD:5131626 NCBI chr 7:55,019,017...55,211,628
Ensembl chr 7:55,019,017...55,211,628 		JBrowse link
G EGR1 early growth response 1 ISO
IEP		 protein:increased expression:lung (human)
mRNA, protein:increased expression:lung (rat)
mRNA, protein:increased expression:lung (mouse)		 RGD PMID:20889906 PMID:21924231 PMID:20889906 PMID:20023177 PMID:18599502 RGD:5131875, RGD:10395308, RGD:5131875, RGD:5131883, RGD:5131890 NCBI chr 5:138,465,479...138,469,303
Ensembl chr 5:138,465,479...138,469,303 		JBrowse link
G EIF2AK4 eukaryotic translation initiation factor 2 alpha kinase 4 EXP CTD Direct Evidence: marker/mechanism CTD PMID:24292273 NCBI chr15:39,934,115...40,035,591
Ensembl chr15:39,934,115...40,035,591 		JBrowse link
G ENG endoglin ISO RGD PMID:20042709 RGD:11041178 NCBI chr 9:127,815,016...127,854,658
Ensembl chr 9:127,811,130...127,854,773 		JBrowse link
G EPAS1 endothelial PAS domain protein 1 ISO
IAGP		 DNA:missense mutation:cds: 2097G>A,p.G537R(human) RGD PMID:16215633 PMID:18650473 RGD:10395375, RGD:11041573 NCBI chr 2:46,297,407...46,386,697
Ensembl chr 2:46,293,667...46,386,697 		JBrowse link
G EPHX2 epoxide hydrolase 2 ISO RGD PMID:19226702 RGD:5688731 NCBI chr 8:27,491,143...27,548,626
Ensembl chr 8:27,490,781...27,545,564 		JBrowse link
G EPO erythropoietin treatment IDA RGD PMID:22559233 RGD:10400914 NCBI chr 7:100,720,468...100,723,700
Ensembl chr 7:100,720,468...100,723,700 		JBrowse link
G ESR1 estrogen receptor 1 IEP RGD PMID:20081107 RGD:4892253 NCBI chr 6:151,656,672...152,129,619
Ensembl chr 6:151,656,691...152,129,619 		JBrowse link
G ESR2 estrogen receptor 2 ISO RGD PMID:21700911 RGD:5508791 NCBI chr14:64,226,707...64,338,613
Ensembl chr14:64,084,232...64,338,112 		JBrowse link
G F5 coagulation factor V IAGP Chronic thromboembolic pulmonary hypertension (CTEPH) RGD PMID:20182352 RGD:4892669 NCBI chr 1:169,511,951...169,586,481
Ensembl chr 1:169,511,951...169,586,588 		JBrowse link
G FBLN5 fibulin 5 EXP CTD Direct Evidence: marker/mechanism CTD PMID:12189163 NCBI chr14:91,869,411...91,947,694
Ensembl chr14:91,869,411...91,947,987 		JBrowse link
G FGF2 fibroblast growth factor 2 ISO
IEP		 mRNA:increased expression:lung RGD PMID:19197140 PMID:19197140 RGD:2315911, RGD:2315911 NCBI chr 4:122,826,682...122,898,236
Ensembl chr 4:122,826,682...122,898,236 		JBrowse link
G FGFR1 fibroblast growth factor receptor 1 ISO RGD PMID:19197140 RGD:2315911 NCBI chr 8:38,411,143...38,468,635
Ensembl chr 8:38,400,215...38,468,834 		JBrowse link
G FOXO1 forkhead box O1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:27663689 NCBI chr13:40,555,667...40,666,641
Ensembl chr13:40,555,667...40,666,641 		JBrowse link
G GATA4 GATA binding protein 4 ISO protein:increased expression:heart right ventricle RGD PMID:21059997 RGD:7207053 NCBI chr 8:11,676,935...11,760,002
Ensembl chr 8:11,676,959...11,760,002 		JBrowse link
G GATA6 GATA binding protein 6 ISO
IEP		 mRNA, protein:decreased expression:lung
protein:decreased expression:lung, arteriole, venule (human)		 RGD PMID:19842842 PMID:23583651 PMID:23583651 RGD:2314194, RGD:13208869, RGD:13208869 NCBI chr18:22,169,589...22,202,528
Ensembl chr18:22,169,589...22,202,528 		JBrowse link
G GBA1 glucosylceramidase beta 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:12359135 NCBI chr 1:155,234,452...155,244,627
Ensembl chr 1:155,234,452...155,244,699 		JBrowse link
G GDF2 growth differentiation factor 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:26801773 NCBI chr10:47,322,454...47,327,588
Ensembl chr10:47,322,454...47,327,588 		JBrowse link
G GJA1 gap junction protein alpha 1 treatment ISO mRNA:increased expression:pulmonary artery RGD PMID:21414209 PMID:23321332 RGD:7207411, RGD:8662411 NCBI chr 6:121,435,646...121,449,727
Ensembl chr 6:121,435,595...121,449,727 		JBrowse link
G GPR182 G protein-coupled receptor 182 ISO mRNA:increased expression:lung RGD PMID:12622928 RGD:1625768 NCBI chr12:56,994,492...56,998,877
Ensembl chr12:56,994,492...56,998,447 		JBrowse link
G HAS1 hyaluronan synthase 1 ISO RGD PMID:19915162 RGD:9588633 NCBI chr19:51,713,112...51,723,991
Ensembl chr19:51,713,112...51,723,991 		JBrowse link
G HAS2 hyaluronan synthase 2 ISO mRNA:increased expression:lung RGD PMID:19915162 RGD:9588633 NCBI chr 8:121,612,116...121,641,440
Ensembl chr 8:121,612,116...121,641,440 		JBrowse link
G HAS3 hyaluronan synthase 3 ISO mRNA:decreased expression:lung RGD PMID:19915162 RGD:9588633 NCBI chr16:69,083,484...69,118,719
Ensembl chr16:69,105,653...69,118,719 		JBrowse link
G HDAC1 histone deacetylase 1 IEP
ISO		 protein:increased expression:lung: RGD PMID:22711276 PMID:22711276 RGD:9590133, RGD:9590133 NCBI chr 1:32,292,083...32,333,626
Ensembl chr 1:32,292,083...32,333,635 		JBrowse link
G HDAC2 histone deacetylase 2 IEP protein:decreased expression:lung: RGD PMID:22711276 RGD:9590133 NCBI chr 6:113,933,028...113,971,148
Ensembl chr 6:113,933,028...114,011,308 		JBrowse link
G HDAC3 histone deacetylase 3 IEP protein:decreased expression:lung: RGD PMID:22711276 RGD:9590133 NCBI chr 5:141,620,881...141,636,849
Ensembl chr 5:141,620,876...141,636,849 		JBrowse link
G HDAC4 histone deacetylase 4 IEP protein:increased expression:lung: RGD PMID:22711276 RGD:9590133 NCBI chr 2:239,048,168...239,401,649
Ensembl chr 2:239,048,168...239,401,654 		JBrowse link
G HDAC5 histone deacetylase 5 IEP
ISO		 protein:increased expression:lung: RGD PMID:22711276 PMID:22711276 RGD:9590133, RGD:9590133 NCBI chr17:44,076,753...44,123,641
Ensembl chr17:44,076,746...44,123,702 		JBrowse link
G HEY1 hes related family bHLH transcription factor with YRPW motif 1 ISO mRNA:decreased expression:lung: RGD PMID:34739767 RGD:155646132 NCBI chr 8:79,764,010...79,767,767
Ensembl chr 8:79,762,371...79,767,857 		JBrowse link
G HIF1A hypoxia inducible factor 1 subunit alpha ISO
EXP		 associated with Anoxia;protein:increased expression:pulmonary artery
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:20110409 PMID:17213961 PMID:16215633 RGD:1601553, RGD:10395375 NCBI chr14:61,695,513...61,748,258
Ensembl chr14:61,695,513...61,748,259 		JBrowse link
G HIF3A hypoxia inducible factor 3 subunit alpha ISO RGD PMID:16215633 RGD:10395375 NCBI chr19:46,297,042...46,343,433
Ensembl chr19:46,297,042...46,343,433 		JBrowse link
G HK1 hexokinase 1 ISO mRNA:increased expression:lung RGD PMID:25767292 RGD:11353880 NCBI chr10:69,270,000...69,401,882
Ensembl chr10:69,269,984...69,401,884 		JBrowse link
G HMGB1 high mobility group box 1 treatment ISO RGD PMID:25032709 RGD:10402082 NCBI chr13:30,456,704...30,617,597
Ensembl chr13:30,456,704...30,617,597 		JBrowse link
G HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase ISO RGD PMID:12750068 RGD:5508701 NCBI chr 5:75,336,529...75,362,116
Ensembl chr 5:75,336,329...75,364,001 		JBrowse link
G HMOX1 heme oxygenase 1 ISO
IDA		 RGD PMID:14970910 PMID:20957739 PMID:19409105 PMID:20957739 RGD:1582715, RGD:4145325, RGD:4145307, RGD:4145325 NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214 		JBrowse link
G HP haptoglobin treatment IEP
IDA		 protein:decreased expression:serum RGD PMID:2043024 PMID:25656991 PMID:19023114 PMID:19703762 RGD:1626353, RGD:11041794, RGD:5147440, RGD:5147420 NCBI chr16:72,054,505...72,061,055
Ensembl chr16:72,054,505...72,061,055 		JBrowse link
G HPGD 15-hydroxyprostaglandin dehydrogenase IEP mRNA, protein:increased expression:lung RGD PMID:24657469 RGD:11667099 NCBI chr 4:174,490,175...174,522,893
Ensembl chr 4:174,490,175...174,523,154 		JBrowse link
G HTR1B 5-hydroxytryptamine receptor 1B ameliorates ISO RGD PMID:28473438 RGD:329955562 NCBI chr 6:77,460,924...77,463,491
Ensembl chr 6:77,460,924...77,463,491 		JBrowse link
G HTR2B 5-hydroxytryptamine receptor 2B EXP CTD Direct Evidence: marker/mechanism CTD PMID:14659797 NCBI chr 2:231,108,230...231,125,042
Ensembl chr 2:231,108,230...231,125,042 		JBrowse link
G HYAL1 hyaluronidase 1 ISO mRNA:decreased expression:lung RGD PMID:19915162 RGD:9588633 NCBI chr 3:50,299,893...50,312,381
Ensembl chr 3:50,299,890...50,312,381 		JBrowse link
G HYAL2 hyaluronidase 2 ISO mRNA:decreased expression:lung RGD PMID:19915162 RGD:9588633 NCBI chr 3:50,317,808...50,322,745
Ensembl chr 3:50,317,790...50,322,782 		JBrowse link
G ICAM1 intercellular adhesion molecule 1 IEP associated with Heart Defects, Congenital;protein:increased secretion:serum (human) RGD PMID:21034646 RGD:4145436 NCBI chr19:10,271,120...10,286,615
Ensembl chr19:10,271,093...10,286,615 		JBrowse link
G ID1 inhibitor of DNA binding 1 ISO RGD PMID:20522807 RGD:9686087 NCBI chr20:31,605,289...31,606,510
Ensembl chr20:31,573,014...31,606,515 		JBrowse link
G IFNGR1 interferon gamma receptor 1 IEP mRNA: increased expression RGD PMID:20808962 RGD:4892610 NCBI chr 6:137,197,484...137,219,385
Ensembl chr 6:137,197,483...137,219,449 		JBrowse link
G IL10 interleukin 10 disease_progression IEP protein:increased expression:serum RGD PMID:20713898 RGD:4142530 NCBI chr 1:206,767,602...206,772,494
Ensembl chr 1:206,767,602...206,774,541 		JBrowse link
G IL13 interleukin 13 IEP associated with sclerosis; protein:increased expression:plasma (human)
associated with Scleroderma, Limited;protein:increased expression:plasma		 RGD PMID:19799786 PMID:21425123 RGD:4145600, RGD:8549528 NCBI chr 5:132,656,522...132,661,110
Ensembl chr 5:132,656,263...132,661,110 		JBrowse link
G IL13RA1 interleukin 13 receptor subunit alpha 1 ISO
IEP		 RGD PMID:20671265 PMID:20808962 RGD:4892611, RGD:4892610 NCBI chr  X:118,727,606...118,805,228
Ensembl chr  X:118,727,133...118,794,535 		JBrowse link
G IL13RA2 interleukin 13 receptor subunit alpha 2 IEP mRNA:increased expression:lung RGD PMID:20522789 RGD:4892612 NCBI chr  X:115,003,982...115,017,616
Ensembl chr  X:115,003,975...115,019,977 		JBrowse link
G IL18 interleukin 18 ISO RGD PMID:17400729 RGD:4889590 NCBI chr11:112,143,260...112,164,094
Ensembl chr11:112,143,251...112,164,096 		JBrowse link
G IL1B interleukin 1 beta IEP associated with Scleroderma, Limited;protein:increased expression:serum RGD PMID:20808962 PMID:20713898 RGD:4892610, RGD:4142530 NCBI chr 2:112,829,751...112,836,779
Ensembl chr 2:112,829,751...112,836,816 		JBrowse link
G IL1RN interleukin 1 receptor antagonist IDA RGD PMID:7946395 RGD:4143197 NCBI chr 2:113,099,360...113,134,014
Ensembl chr 2:113,099,315...113,134,016 		JBrowse link
G IL23R interleukin 23 receptor IAGP associated with Scleroderma, Systemic;DNA:SNPs: :rs11209026, rs11465804 (human) RGD PMID:19918037 RGD:5096624 NCBI chr 1:67,138,637...67,265,903
Ensembl chr 1:67,138,907...67,259,979 		JBrowse link
G IL4 interleukin 4 ISO RGD PMID:20889544 RGD:5128515 NCBI chr 5:132,673,989...132,682,678
Ensembl chr 5:132,673,986...132,682,678 		JBrowse link
G IL6 interleukin 6 disease_progression
ameliorates		 IEP
ISO		 RGD PMID:20713898 PMID:38602915 PMID:20693255 RGD:4142530, RGD:407450417, RGD:4143246 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
G KCNA5 potassium voltage-gated channel subfamily A member 5 IAGP
EXP
ISO
IEP		 DNA:SNPs:promoter, cds
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:27522126 PMID:17267549 PMID:20303989 PMID:17596340 RGD:1627654, RGD:7242752, RGD:1627651 NCBI chr12:5,043,879...5,046,788
Ensembl chr12:5,043,879...5,046,788 		JBrowse link
G KCNK3 potassium two pore domain channel subfamily K member 3 severity EXP
ISO		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:30365877 PMID:31347976 RGD:151347452 NCBI chr 2:26,692,722...26,733,420
Ensembl chr 2:26,692,722...26,733,420 		JBrowse link
G KCNMA1 potassium calcium-activated channel subfamily M alpha 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:28090300 NCBI chr10:76,869,602...77,637,808
Ensembl chr10:76,869,601...77,638,369 		JBrowse link
G KDM5B lysine demethylase 5B ISO associated with Hypoxia;protein:increased expression:pulmonary artery,smooth muscle tissue (mouse) RGD PMID:30172777 RGD:329955443 NCBI chr 1:202,724,495...202,808,421
Ensembl chr 1:202,724,495...202,808,487 		JBrowse link
G LCN2 lipocalin 2 ISO
IEP		 mRNA,protein:increased expression:lung
associated with congenital heart disease; protein:increased expression:plasma		 RGD PMID:25076856 PMID:25076856 RGD:126781744, RGD:126781744 NCBI chr 9:128,149,453...128,153,453
Ensembl chr 9:128,149,071...128,153,453 		JBrowse link
G LEPR leptin receptor EXP CTD Direct Evidence: marker/mechanism CTD PMID:30689673 NCBI chr 1:65,420,652...65,641,559
Ensembl chr 1:65,420,652...65,641,559 		JBrowse link
G LOX lysyl oxidase EXP CTD Direct Evidence: marker/mechanism CTD PMID:24614111 NCBI chr 5:122,063,195...122,078,259
Ensembl chr 5:122,063,195...122,078,413 		JBrowse link
G MAPK1 mitogen-activated protein kinase 1 treatment IDA RGD PMID:25907942 RGD:13800893 NCBI chr22:21,759,657...21,867,680
Ensembl chr22:21,759,657...21,867,680 		JBrowse link
G MAPK3 mitogen-activated protein kinase 3 treatment IDA RGD PMID:25907942 RGD:13800893 NCBI chr16:30,114,105...30,123,220
Ensembl chr16:30,114,105...30,123,506 		JBrowse link
G MFN1 mitofusin 1 ISO protein:decreased expression:heart right ventricle (rat) RGD PMID:27422986 RGD:12910832 NCBI chr 3:179,347,709...179,394,936
Ensembl chr 3:179,347,709...179,394,936 		JBrowse link
G MIF macrophage migration inhibitory factor IEP associated with sclerodema, systemic; protein:increased expression:serum RGD PMID:18618071 RGD:4891006 NCBI chr22:23,894,383...23,895,223
Ensembl chr22:23,894,383...23,895,227 		JBrowse link
G MIR125A microRNA 125a treatment ISO RGD PMID:29700287 RGD:26884455 NCBI chr19:51,693,254...51,693,339
Ensembl chr19:51,693,254...51,693,339 		JBrowse link
G MIR145 microRNA 145 ISO mRNA:decreased expression:pulmonary artery (rat) RGD PMID:35369850 RGD:155230820 NCBI chr 5:149,430,646...149,430,733
Ensembl chr 5:149,430,646...149,430,733 		JBrowse link
G MIR204 microRNA 204 EXP CTD Direct Evidence: marker/mechanism CTD PMID:26224795 NCBI chr 9:70,809,975...70,810,084
Ensembl chr 9:70,809,975...70,810,084 		JBrowse link
G MIR21 microRNA 21 ISO RNA:increased expression:lung RGD PMID:32402408 RGD:41410883 NCBI chr17:59,841,266...59,841,337
Ensembl chr17:59,841,266...59,841,337 		JBrowse link
G MIR223 microRNA 223 treatment ISO
IEP		 associated with Chronic Intermittent Hypoxia
RNA:decreased expression:lung, pulmonary aorta, pulmonary aorta smooth muscle		 RGD PMID:30246291 PMID:30507047 PMID:26084306 PMID:26084306 RGD:25823198, RGD:25824849, RGD:25824847, RGD:25824847 NCBI chr  X:66,018,870...66,018,979
Ensembl chr  X:66,018,870...66,018,979 		JBrowse link
G MMP1 matrix metallopeptidase 1 ISO RGD PMID:23087098 RGD:7207217 NCBI chr11:102,789,919...102,798,160
Ensembl chr11:102,789,401...102,798,160 		JBrowse link
G MMP9 matrix metallopeptidase 9 severity IMP
ISO
IEP		 associated with Heart Failure, Congestive;protein:decreased expression:monocyte
associated with Pulmonary Embolism;protein:increased expression:lung, plasma		 RGD PMID:21063214 PMID:23087098 PMID:16867026 PMID:17133179 PMID:18355767 RGD:5129210, RGD:7207217, RGD:1642028, RGD:1642053, RGD:5130155 NCBI chr20:46,008,908...46,016,561
Ensembl chr20:46,008,908...46,016,561 		JBrowse link
G MTOR mechanistic target of rapamycin kinase ISO RGD PMID:23470622 RGD:10041039 NCBI chr 1:11,106,535...11,262,551
Ensembl chr 1:11,106,535...11,262,556 		JBrowse link
G MYC MYC proto-oncogene, bHLH transcription factor treatment ISO RGD PMID:22306243 RGD:7240564 NCBI chr 8:127,735,434...127,742,951
Ensembl chr 8:127,735,434...127,742,951 		JBrowse link
G NAMPT nicotinamide phosphoribosyltransferase susceptibility IEP
ISO		 mRNA,protein:increased expression:lung,pulmonary arterial endothelial cell:
protein:increased expression:lung:		 RGD PMID:28202489 PMID:28202489 PMID:28202489 RGD:13781882, RGD:13781882, RGD:13781882 NCBI chr 7:106,248,298...106,285,888
Ensembl chr 7:106,248,298...106,285,966 		JBrowse link
G NFATC2 nuclear factor of activated T cells 2 ISO
EXP		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:27522126 PMID:17596340 RGD:1627651 NCBI chr20:51,386,963...51,562,839
Ensembl chr20:51,386,957...51,562,831 		JBrowse link
G NOS2 nitric oxide synthase 2 onset IEP
ISO
IAGP		 associated with heart disease; protein:increased expression:endothelial cell
associated with Anoxia; protein:increased expression:pulmonary artery
associated with Congenital diaphragmatic hernia; protein:decreased expression:pulmonary artery, endothelium
associated with Scleroderma, Systemic; DNA:repeats, SNPs:promoter:(CCTTT), c.-1026C>T, c.-277A>G (human)
associated with Anoxia; mouse gene in rat model		 RGD PMID:19912632 PMID:16113050 PMID:16456243 PMID:16813666 PMID:11104748 RGD:5132602, RGD:1580936, RGD:1580940, RGD:4891462, RGD:4891468 NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529 		JBrowse link
G NOS3 nitric oxide synthase 3 treatment
susceptibility		 IEP
EXP
ISO
IAGP		 associated with heart disease; protein:increased expression:endothelial cell
CTD Direct Evidence: marker/mechanism
associated with Beta-Thalassemia;DNA:repeats:intron:
mRNA, protein:increased expression:pulmonary endothelial cell
RNA:increased expression:lung
DNA:polymorphism:cds:p.E298D (human)
associated with chronic obstructive pulmonary disease; DNA:polymorphism:cds:p.G894T (human)
protein:increased expression:arteriole		 CTD
RGD		 PMID:21144100 PMID:19912632 PMID:29151278 PMID:25699607 PMID:20724942 More... RGD:5132602, RGD:13504742, RGD:11533642, RGD:4892004, RGD:5132631, RGD:4892009, RGD:4892039, RGD:4892042, RGD:4892043, RGD:4892038, RGD:4892010 NCBI chr 7:150,991,017...151,014,588
Ensembl chr 7:150,991,017...151,014,588 		JBrowse link
G NOTCH1 notch receptor 1 ameliorates ISO RGD PMID:34739767 RGD:155646132 NCBI chr 9:136,494,433...136,546,048
Ensembl chr 9:136,494,433...136,546,048 		JBrowse link
G NOX1 NADPH oxidase 1 treatment
ameliorates		 ISO mRNA,protein:increased expression:lung RGD PMID:24233492 PMID:23706097 PMID:27401289 PMID:24233492 RGD:329955359, RGD:329955579, RGD:329955361, RGD:329955359 NCBI chr  X:100,843,324...100,874,359
Ensembl chr  X:100,843,324...100,874,359 		JBrowse link
G NOX4 NADPH oxidase 4 ISO associated with Anoxia;mRNA, protein:increased expression:lung RGD PMID:18952568 RGD:4762683 NCBI chr11:89,324,353...89,589,557
Ensembl chr11:89,324,353...89,498,187 		JBrowse link
G NPPA natriuretic peptide A ISO RGD PMID:2136863 RGD:7247720 NCBI chr 1:11,845,709...11,847,783
Ensembl chr 1:11,845,709...11,848,345 		JBrowse link
G NPPB natriuretic peptide B severity IEP
EXP
ISO		 protein:increased expression:plasma
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:20408845 PMID:21351102 PMID:16893710 PMID:16936438 RGD:1642205, RGD:1642203 NCBI chr 1:11,857,464...11,858,945
Ensembl chr 1:11,857,464...11,858,945 		JBrowse link
G PDE3A phosphodiesterase 3A ISO mRNA:increased expression:pulmonary artery RGD PMID:12466227 RGD:1582528 NCBI chr12:20,368,537...20,688,583
Ensembl chr12:20,368,537...20,688,583 		JBrowse link
G PDE5A phosphodiesterase 5A ISO RGD PMID:19881228 RGD:2314460 NCBI chr 4:119,494,403...119,628,804
Ensembl chr 4:119,494,397...119,628,804 		JBrowse link
G PDGFA platelet derived growth factor subunit A ISO RGD PMID:8447423 RGD:1580847 NCBI chr 7:497,258...520,700
Ensembl chr 7:497,258...520,296 		JBrowse link
G PDGFB platelet derived growth factor subunit B ISO
IEP		 RGD PMID:8447423 PMID:21819559 PMID:22523431 RGD:1580847, RGD:6482859, RGD:6482831 NCBI chr22:39,223,359...39,244,982
Ensembl chr22:39,223,359...39,244,982 		JBrowse link
G PDIA3 protein disulfide isomerase family A member 3 ISO protein:increased expression:lung: RGD PMID:23315792 RGD:9999167 NCBI chr15:43,746,438...43,773,278
Ensembl chr15:43,746,394...43,773,279 		JBrowse link
G PECAM1 platelet and endothelial cell adhesion molecule 1 treatment ISO RGD PMID:22559233 RGD:10400914 NCBI chr17:64,319,415...64,390,860
Ensembl chr17:64,319,415...64,413,776 		JBrowse link
G PGF placental growth factor IEP associated with Anemia, Sickle Cell;protein:increased expression:plasma
associated with Heart Defects, Congenital		 RGD PMID:20040765 PMID:20195855 RGD:6483588, RGD:6483610 NCBI chr14:74,941,830...74,955,764
Ensembl chr14:74,941,834...74,955,626 		JBrowse link
G PRKG1 protein kinase cGMP-dependent 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:21351102 NCBI chr10:50,990,888...52,298,350
Ensembl chr10:50,990,888...52,298,423 		JBrowse link
G PTGIS prostaglandin I2 synthase treatment
susceptibility		 ISO
IEP
IMP		 protein:decreased expression:pulmonary artery (human)
human gene in a rat model
rat gene in a mouse model		 RGD PMID:15684702 PMID:32673988 PMID:12019369 PMID:10359560 RGD:1580695, RGD:401960100, RGD:401959405, RGD:727270 NCBI chr20:49,503,874...49,568,137
Ensembl chr20:49,503,874...49,568,137 		JBrowse link
G PTGS2 prostaglandin-endoperoxide synthase 2 ISO anoxia associated; RGD PMID:18542928 PMID:19577709 RGD:2300276, RGD:5135495 NCBI chr 1:186,671,791...186,680,423
Ensembl chr 1:186,671,791...186,680,922 		JBrowse link
G PTK2 protein tyrosine kinase 2 IAGP RGD PMID:16244766 RGD:1581290 NCBI chr 8:140,657,900...141,002,079
Ensembl chr 8:140,657,900...141,002,216 		JBrowse link
G RAMP2 receptor activity modifying protein 2 ISO mRNA:increased expression:heart right ventricle RGD PMID:17437045 RGD:1642678 NCBI chr17:42,761,227...42,763,041
Ensembl chr17:42,758,447...42,763,041 		JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit ISO protein:altered localization:nucleus, blood vessel endothelial cell, lung
associated with Hypoxia;protein:increased expression:pulmonary artery,smooth muscle tissue (mouse)		 RGD PMID:17934115 PMID:30172777 RGD:2298843, RGD:329955443 NCBI chr11:65,653,601...65,663,857
Ensembl chr11:65,653,599...65,663,090 		JBrowse link
G RHOA ras homolog family member A ISO protein:altered localization:pulmonary artery
protein:altered localization:membrane, artery, lung		 RGD PMID:16322374 PMID:18091588 RGD:1642819, RGD:2298877 NCBI chr 3:49,359,145...49,411,976
Ensembl chr 3:49,359,139...49,412,998 		JBrowse link
G RYR1 ryanodine receptor 1 ISO protein:altered localization: : RGD PMID:24692174 RGD:329813077 NCBI chr19:38,433,691...38,587,564
Ensembl chr19:38,433,691...38,595,273 		JBrowse link
G RYR2 ryanodine receptor 2 ISO protein:increased expression:pulmonary artery RGD PMID:22962011 RGD:329813078 NCBI chr 1:237,042,184...237,833,988
Ensembl chr 1:237,042,184...237,833,988 		JBrowse link
G RYR3 ryanodine receptor 3 ISO protein:altered localization: : RGD PMID:24692174 RGD:329813077 NCBI chr15:33,310,967...33,866,102
Ensembl chr15:33,310,962...33,866,121 		JBrowse link
G SERPINA1 serpin family A member 1 IEP
ISO		 protein:decreased expression:serum RGD PMID:17444595 PMID:1836309 RGD:1643144, RGD:1643154 NCBI chr14:94,376,747...94,390,635
Ensembl chr14:94,376,747...94,390,693 		JBrowse link
G SERPINE1 serpin family E member 1 treatment IAGP
ISO
IEP		 DNA:polymorphism:3'utr
mRNA, protein:decreased expression:lung		 RGD PMID:20300292 PMID:27115515 PMID:18337154 RGD:4143527, RGD:11073610, RGD:4143529 NCBI chr 7:101,127,104...101,139,247
Ensembl chr 7:101,127,104...101,139,247 		JBrowse link
G SLC1A5 solute carrier family 1 member 5 IEP protein:increased expression:myocytes plasma membrane, right ventricle RGD PMID:23794090 RGD:151361111 NCBI chr19:46,774,883...46,788,594
Ensembl chr19:46,774,883...46,788,594 		JBrowse link
G SLC2A4 solute carrier family 2 member 4 ISO RGD PMID:19043358 RGD:2313622 NCBI chr17:7,281,718...7,288,257
Ensembl chr17:7,281,718...7,288,257 		JBrowse link
G SLC31A1 solute carrier family 31 member 1 EXP CTD Direct Evidence: marker/mechanism CTD PMID:24614111 NCBI chr 9:113,221,544...113,264,492
Ensembl chr 9:113,221,544...113,264,492 		JBrowse link
G SLC6A4 solute carrier family 6 member 4 severity
no_association
onset		 ISO
EXP
IAGP
IMP		 CTD Direct Evidence: marker/mechanism
associated with Heart Septal Defects, Ventricular;DNA:polymorphisms (human)
associated with Anoxia
associated with Pulmonary Disease, Chronic Obstructive;DNA:polymorphism (human)
DNA:polymorphism, repeat:promoter, intron (human)
DNA:repeat:promoter (human)		 CTD
RGD		 PMID:18506000 PMID:18074800 PMID:19886858 PMID:11259539 PMID:19736308 More... RGD:4889437, RGD:4889430, RGD:4889445, RGD:4889432, RGD:4889434, RGD:4889440, RGD:4889432, RGD:4889435, RGD:4889442 NCBI chr17:30,194,319...30,235,697
Ensembl chr17:30,194,319...30,236,002 		JBrowse link
G SLC8A1 solute carrier family 8 member A1 IEP protein:increased expression:pulmonary artery, smooth muscle cell RGD PMID:17192285 RGD:1642711 NCBI chr 2:40,097,270...40,512,435
Ensembl chr 2:40,097,270...40,611,053 		JBrowse link
G SMAD1 SMAD family member 1 ISO protein:decreased phosphorylation:lung, vascular associated smooth muscle cell
protein:decreased expression, increased phosphorylation:lung		 RGD PMID:17347486 PMID:18367643 RGD:1643222, RGD:12903274 NCBI chr 4:145,480,770...145,559,176
Ensembl chr 4:145,481,194...145,559,176 		JBrowse link
G SMAD4 SMAD family member 4 ISO RGD PMID:17347486 PMID:18367643 RGD:1643222, RGD:12903274 NCBI chr18:51,030,213...51,085,042
Ensembl chr18:51,028,528...51,085,045 		JBrowse link
G SMAD6 SMAD family member 6 ISO mRNA:decreased expression:lung RGD PMID:17347486 RGD:1643222 NCBI chr15:66,702,236...66,782,849
Ensembl chr15:66,702,236...66,782,849 		JBrowse link
G SMAD7 SMAD family member 7 ISO RGD PMID:17347486 RGD:1643222 NCBI chr18:48,919,853...48,950,965
Ensembl chr18:48,919,853...48,950,965 		JBrowse link
G SMAD9 SMAD family member 9 ISO RGD PMID:17347486 RGD:1643222 NCBI chr13:36,844,831...36,920,854
Ensembl chr13:36,844,831...36,920,887 		JBrowse link
G SMPD3 sphingomyelin phosphodiesterase 3 treatment ISO RGD PMID:19088082 RGD:10042965 NCBI chr16:68,358,327...68,448,508
Ensembl chr16:68,358,327...68,448,508 		JBrowse link
G SOD2 superoxide dismutase 2 EXP CTD Direct Evidence: marker/mechanism CTD PMID:20110409 NCBI chr 6:159,669,069...159,762,281
Ensembl chr 6:159,669,069...159,762,529 		JBrowse link
G SOX17 SRY-box transcription factor 17 ISO protein:decreased expression:lung (rat) RGD PMID:36913491 RGD:329853317 NCBI chr 8:54,457,935...54,460,892
Ensembl chr 8:54,457,935...54,460,892 		JBrowse link
G STAT3 signal transducer and activator of transcription 3 severity ISO protein:increased phosphorylation:lung RGD PMID:38602915 RGD:407450417 NCBI chr17:42,313,324...42,388,442
Ensembl chr17:42,313,324...42,388,568 		JBrowse link
G TAC1 tachykinin precursor 1 ISO RGD PMID:12662901 RGD:5147638 NCBI chr 7:97,732,086...97,740,472
Ensembl chr 7:97,732,084...97,740,472 		JBrowse link
G TACR1 tachykinin receptor 1 ISO RGD PMID:12662901 RGD:5147638 NCBI chr 2:75,046,463...75,199,520
Ensembl chr 2:75,046,463...75,199,520 		JBrowse link
G TACR2 tachykinin receptor 2 ISO RGD PMID:12662901 RGD:5147638 NCBI chr10:69,403,903...69,416,918
Ensembl chr10:69,403,903...69,416,918 		JBrowse link
G TEK TEK receptor tyrosine kinase IEP mRNA, protein:increased expression:lung RGD PMID:16917117 RGD:1601487 NCBI chr 9:27,109,225...27,230,174
Ensembl chr 9:27,109,141...27,230,174 		JBrowse link
G TERT telomerase reverse transcriptase treatment ISO
IEP		 RGD PMID:24376652 PMID:24376652 RGD:11038675, RGD:11038675 NCBI chr 5:1,253,167...1,295,068
Ensembl chr 5:1,253,147...1,295,068 		JBrowse link
G TGFA transforming growth factor alpha EXP CTD Direct Evidence: marker/mechanism CTD PMID:18424623 NCBI chr 2:70,447,284...70,553,826
Ensembl chr 2:70,447,284...70,554,193 		JBrowse link
G TGFB1 transforming growth factor beta 1 onset IAGP
IEP		 DNA:SNPs: :multiple (human)
protein:increased expression:blood		 RGD PMID:18496036 PMID:19324949 RGD:4145273, RGD:4145138 NCBI chr19:41,330,323...41,353,922
Ensembl chr19:41,301,587...41,353,922 		JBrowse link
G TGFBR1 transforming growth factor beta receptor 1 ISO RGD PMID:18202349 RGD:2302019 NCBI chr 9:99,103,647...99,154,192
Ensembl chr 9:99,104,038...99,154,192 		JBrowse link
G TGFBR2 transforming growth factor beta receptor 2 ISO mRNA:decreased expression:lung RGD PMID:17392319 RGD:1601116 NCBI chr 3:30,606,356...30,694,142
Ensembl chr 3:30,606,478...30,694,249 		JBrowse link
G THBD thrombomodulin IEP associated with Mixed Connective Tissue Disease RGD PMID:16784493 RGD:1601639 NCBI chr20:23,045,633...23,049,672
Ensembl chr20:23,045,633...23,049,672 		JBrowse link
G THPO thrombopoietin IEP protein:increased expression:pulmonary artery, plasma RGD PMID:12487786 RGD:1580087 NCBI chr 3:184,371,935...184,379,688
Ensembl chr 3:184,371,935...184,381,968 		JBrowse link
G TLR4 toll like receptor 4 ISO associated anoxia RGD PMID:20205596 RGD:4144108 NCBI chr 9:117,704,403...117,724,735
Ensembl chr 9:117,704,175...117,724,735 		JBrowse link
G TNC tenascin C severity ISO
IEP		 protein:increased expression:plasma RGD PMID:19288153 PMID:20528622 PMID:16782755 PMID:15879421 RGD:4889564, RGD:4889562, RGD:4889567, RGD:4889570 NCBI chr 9:115,019,575...115,118,157
Ensembl chr 9:115,019,575...115,118,207 		JBrowse link
G TNF tumor necrosis factor IEP
EXP
ISO		 associated with pulmonary disease, chronic obstructive; protein:increased expression:serum
CTD Direct Evidence: therapeutic
associated with Pulmonary Edema; protein:increased expression:Bronchoalveolar Lavage Fluid		 CTD
RGD		 PMID:2518282 PMID:16899829 PMID:9628235 PMID:12391106 RGD:4143280, RGD:4142833, RGD:4143422 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
G TP53 tumor protein p53 treatment ISO RGD PMID:24334871 RGD:10043360 NCBI chr17:7,668,421...7,687,490
Ensembl chr17:7,661,779...7,687,546 		JBrowse link
G TP53BP1 tumor protein p53 binding protein 1 IEP protein:increased expression:lung RGD PMID:24270264 RGD:9586752 NCBI chr15:43,403,061...43,510,640
Ensembl chr15:43,403,061...43,510,728 		JBrowse link
G TPH1 tryptophan hydroxylase 1 severity ISO
EXP		 CTD Direct Evidence: marker/mechanism CTD
RGD		 PMID:18506000 PMID:17675372 RGD:5686352 NCBI chr11:18,017,555...18,046,269
Ensembl chr11:18,017,555...18,046,269 		JBrowse link
G TPH2 tryptophan hydroxylase 2 severity ISO DNA:SNP: :1473C>G (mouse) RGD PMID:17675372 RGD:5686352 NCBI chr12:71,938,845...72,032,440
Ensembl chr12:71,938,845...72,186,618 		JBrowse link
G TRPC3 transient receptor potential cation channel subfamily C member 3 IEP RGD PMID:15358862 RGD:1580490 NCBI chr 4:121,874,481...121,952,060
Ensembl chr 4:121,874,481...121,952,060 		JBrowse link
G TRPC6 transient receptor potential cation channel subfamily C member 6 IEP RGD PMID:15358862 RGD:1580490 NCBI chr11:101,451,564...101,584,007
Ensembl chr11:101,451,564...101,872,562 		JBrowse link
G TRPV4 transient receptor potential cation channel subfamily V member 4 ISO protein:increased expression:pulmonary artery RGD PMID:22962011 RGD:329813078 NCBI chr12:109,783,087...109,833,398
Ensembl chr12:109,783,087...109,833,406 		JBrowse link
G TWIST1 twist family bHLH transcription factor 1 treatment ISO RGD PMID:25593290 RGD:38500244 NCBI chr 7:19,113,047...19,117,636
Ensembl chr 7:19,020,991...19,117,636 		JBrowse link
G UTS2 urotensin 2 ISO RGD PMID:15042392 RGD:2306848 NCBI chr 1:7,847,612...7,913,249
Ensembl chr 1:7,843,083...7,853,512 		JBrowse link
G VCAM1 vascular cell adhesion molecule 1 ISO protein:increased expression:blood vessel endothelium RGD PMID:17934115 RGD:2298843 NCBI chr 1:100,719,742...100,739,045
Ensembl chr 1:100,719,742...100,739,045 		JBrowse link
G VEGFA vascular endothelial growth factor A ISO associated with Hypoxia;protein:increased expression:pulmonary artery,smooth muscle tissue (mouse) RGD PMID:30172777 RGD:329955443 NCBI chr 6:43,770,211...43,786,487
Ensembl chr 6:43,770,184...43,786,487 		JBrowse link
G VEGFB vascular endothelial growth factor B IDA RGD PMID:12547729 RGD:1625708 NCBI chr11:64,234,584...64,239,264
Ensembl chr11:64,234,584...64,239,264 		JBrowse link
G VIM vimentin ISO protein:increased expression, increased phosphorylation:lung RGD PMID:25593290 RGD:38500244 NCBI chr10:17,228,241...17,237,593
Ensembl chr10:17,228,241...17,237,593 		JBrowse link
G VIP vasoactive intestinal peptide ISO RGD PMID:22140628 RGD:5685374 NCBI chr 6:152,750,797...152,759,760
Ensembl chr 6:152,750,797...152,759,765 		JBrowse link
G VWF von Willebrand factor IDA RGD PMID:14507115 RGD:1580645 NCBI chr12:5,948,877...6,124,670
Ensembl chr12:5,948,877...6,124,770 		JBrowse link
Pulmonary Hypertension, Chronic Thromboembolic, without Deep Vein Thrombosis term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G HLA-DPB1 major histocompatibility complex, class II, DP beta 1 susceptibility IAGP DNA:polymorphisms:cds:HLA-DPB1*0202 (human) RGD PMID:19165231 RGD:5143999 NCBI chr 6:33,075,990...33,089,696
Ensembl chr 6:33,075,936...33,089,696 		JBrowse link
Pulmonary Hypertension, Hypoxia-Induced term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AHR aryl hydrocarbon receptor treatment ISO RGD PMID:33836606 RGD:401940192 NCBI chr 7:17,298,652...17,346,147
Ensembl chr 7:16,916,359...17,346,152 		JBrowse link
G CYP1A1 cytochrome P450 family 1 subfamily A member 1 ISO mRNA:increased expression:lung (rat) RGD PMID:33836606 RGD:401940192 NCBI chr15:74,719,542...74,725,528
Ensembl chr15:74,719,542...74,725,536 		JBrowse link
G EGFR epidermal growth factor receptor treatment ISO RGD PMID:31264901 RGD:38599217 NCBI chr 7:55,019,017...55,211,628
Ensembl chr 7:55,019,017...55,211,628 		JBrowse link
G EGLN1 egl-9 family hypoxia inducible factor 1 ISO RGD PMID:16761101 RGD:11252085 NCBI chr 1:231,363,756...231,422,287
Ensembl chr 1:231,363,751...231,422,287 		JBrowse link
G EGLN3 egl-9 family hypoxia inducible factor 3 ISO RGD PMID:16761101 RGD:11252085 NCBI chr14:33,924,227...33,951,074
Ensembl chr14:33,924,227...34,462,774 		JBrowse link
G G6PD glucose-6-phosphate dehydrogenase treatment ISO RGD PMID:25063801 RGD:10449119 NCBI chr  X:154,531,390...154,547,569
Ensembl chr  X:154,517,825...154,547,572 		JBrowse link
G GOT1 glutamic-oxaloacetic transaminase 1 ISO mRNA:decreased expression:lung (rat) RGD PMID:19823174 RGD:4145499 NCBI chr10:99,396,870...99,430,624
Ensembl chr10:99,396,870...99,430,624 		JBrowse link
G GOT2 glutamic-oxaloacetic transaminase 2 ISO mRNA:decreased expression:lung (rat) RGD PMID:19823174 RGD:4145499 NCBI chr16:58,707,131...58,734,316
Ensembl chr16:58,707,131...58,734,342 		JBrowse link
G HPGD 15-hydroxyprostaglandin dehydrogenase ISO mRNA, protein:increased expression:lung RGD PMID:24657469 RGD:11667099 NCBI chr 4:174,490,175...174,522,893
Ensembl chr 4:174,490,175...174,523,154 		JBrowse link
G IL6 interleukin 6 ameliorates ISO RGD PMID:38602915 RGD:407450417 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
G MFN2 mitofusin 2 ISO mRNA, protein:decreased expression:lung (rat) RGD PMID:26485208 RGD:12910856 NCBI chr 1:11,980,444...12,013,508
Ensembl chr 1:11,980,181...12,015,211 		JBrowse link
G NOG noggin ISO mRNA,protein:decreased expression:lung: RGD PMID:25740156 RGD:12801489 NCBI chr17:56,593,699...56,595,611
Ensembl chr17:56,593,699...56,595,611 		JBrowse link
G NOS3 nitric oxide synthase 3 ISO mRNA,protein:increased expression:pulmonary artery RGD PMID:9950873 RGD:11533933 NCBI chr 7:150,991,017...151,014,588
Ensembl chr 7:150,991,017...151,014,588 		JBrowse link
G PCNA proliferating cell nuclear antigen ISO protein:increased expression:lung (rat) RGD PMID:26485208 RGD:12910856 NCBI chr20:5,114,953...5,126,622
Ensembl chr20:5,114,953...5,126,626 		JBrowse link
G PTGIS prostaglandin I2 synthase treatment ISO RGD PMID:12062720 RGD:401959327 NCBI chr20:49,503,874...49,568,137
Ensembl chr20:49,503,874...49,568,137 		JBrowse link
G PTPRD protein tyrosine phosphatase receptor type D ISO mRNA, protein:decreased expression:pulmonary artery (rat) RGD PMID:35848503 RGD:401976433 NCBI chr 9:8,314,246...10,613,002
Ensembl chr 9:8,314,246...10,613,002 		JBrowse link
G SLC39A12 solute carrier family 39 member 12 severity ISO RGD PMID:26258299 PMID:26258299 RGD:10401832, RGD:10401832 NCBI chr10:17,951,918...18,043,285
Ensembl chr10:17,951,839...18,043,292 		JBrowse link
G SOX17 SRY-box transcription factor 17 exacerbates ISO protein:decreased expression:pulmonary artery endothelium (mouse) RGD PMID:37066790 PMID:36919784 PMID:36205124 PMID:36913491 RGD:329853316, RGD:329853737, RGD:329853734, RGD:329853317 NCBI chr 8:54,457,935...54,460,892
Ensembl chr 8:54,457,935...54,460,892 		JBrowse link
G STAT3 signal transducer and activator of transcription 3 ISO protein:increased phosphorylation:lung RGD PMID:38602915 RGD:407450417 NCBI chr17:42,313,324...42,388,442
Ensembl chr17:42,313,324...42,388,568 		JBrowse link
pulmonary venoocclusive disease term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATF4 activating transcription factor 4 ISO protein:increased expression:lung RGD PMID:32209028 RGD:38549370 NCBI chr22:39,520,559...39,522,686
Ensembl chr22:39,519,695...39,522,686 		JBrowse link
G BMPR2 bone morphogenetic protein receptor type 2 EXP CTD Direct Evidence: marker/mechanism CTD NCBI chr 2:202,376,327...202,567,749
Ensembl chr 2:202,376,327...202,567,751 		JBrowse link
G DDIT3 DNA damage inducible transcript 3 IEP
ISO		 protein:increased expression:lung, endothelial cell RGD PMID:32209028 PMID:32209028 RGD:38549370, RGD:38549370 NCBI chr12:57,516,588...57,520,517
Ensembl chr12:57,516,588...57,521,737 		JBrowse link
G EIF2AK2 eukaryotic translation initiation factor 2 alpha kinase 2 ISO protein:increased expression:lung RGD PMID:32209028 RGD:38549370 NCBI chr 2:37,099,210...37,156,980
Ensembl chr 2:37,099,210...37,157,522 		JBrowse link
G EIF2AK3 eukaryotic translation initiation factor 2 alpha kinase 3 ISO protein:increased expression:lung RGD PMID:32209028 RGD:38549370 NCBI chr 2:88,556,741...88,628,145
Ensembl chr 2:88,556,741...88,691,518 		JBrowse link
G EIF2AK4 eukaryotic translation initiation factor 2 alpha kinase 4 disease_progression IEP
EXP
ISO		 protein:decreased expression:lung
CTD Direct Evidence: marker/mechanism		 CTD
RGD		 PMID:24292273 PMID:32209028 PMID:32209028 RGD:38549370, RGD:38549370 NCBI chr15:39,934,115...40,035,591
Ensembl chr15:39,934,115...40,035,591 		JBrowse link
G ERG ETS transcription factor ERG ISO
IEP		 protein:decreased expression:lung RGD PMID:32209028 PMID:32209028 RGD:38549370, RGD:38549370 NCBI chr21:38,367,261...38,661,783
Ensembl chr21:38,380,027...38,661,780 		JBrowse link
G HMOX1 heme oxygenase 1 IEP
ISO		 protein:increased expression:lung, endothelial cell RGD PMID:32209028 PMID:32209028 RGD:38549370, RGD:38549370 NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214 		JBrowse link
G KCNK3 potassium two pore domain channel subfamily K member 3 ISO RGD PMID:32209028 RGD:38549370 NCBI chr 2:26,692,722...26,733,420
Ensembl chr 2:26,692,722...26,733,420 		JBrowse link
pulmonary venoocclusive disease 1 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMPR2 bone morphogenetic protein receptor type 2 IAGP ClinVar Annotator: match by term: Pulmonary venoocclusive disease 1 OMIM
ClinVar		 PMID:3291115 PMID:10903931 PMID:11115378 PMID:12045205 PMID:12446270 More... NCBI chr 2:202,376,327...202,567,749
Ensembl chr 2:202,376,327...202,567,751 		JBrowse link
G EIF2AK4 eukaryotic translation initiation factor 2 alpha kinase 4 IAGP ClinVar Annotator: match by term: Pulmonary venoocclusive disease 1 ClinVar PMID:24033266 NCBI chr15:39,934,115...40,035,591
Ensembl chr15:39,934,115...40,035,591 		JBrowse link
pulmonary venoocclusive disease 2 term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BMPR2 bone morphogenetic protein receptor type 2 IAGP ClinVar Annotator: match by term: Familial pulmonary capillary hemangiomatosis ClinVar PMID:18626305 PMID:24292273 NCBI chr 2:202,376,327...202,567,749
Ensembl chr 2:202,376,327...202,567,751 		JBrowse link
G EIF2AK4 eukaryotic translation initiation factor 2 alpha kinase 4 IAGP ClinVar Annotator: match by term: Familial pulmonary capillary hemangiomatosis
ClinVar Annotator: match by term: EIF2AK4-related condition | ClinVar Annotator: match by term: Familial pulmonary capillary hemangiomatosis		 OMIM
ClinVar		 PMID:12215525 PMID:24033266 PMID:24135949 PMID:24292273 PMID:24310610 More... NCBI chr15:39,934,115...40,035,591
Ensembl chr15:39,934,115...40,035,591 		JBrowse link
G LOC130056813 ATAC-STARR-seq lymphoblastoid silent region 6314 IAGP ClinVar Annotator: match by term: Familial pulmonary capillary hemangiomatosis
ClinVar Annotator: match by term: EIF2AK4-related condition		 ClinVar PMID:24033266 PMID:25741868 PMID:28492532 NCBI chr15:39,933,988...39,934,397 JBrowse link
renal hypertension term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AGT angiotensinogen EXP CTD Direct Evidence: marker/mechanism CTD PMID:8763405 NCBI chr 1:230,702,523...230,745,583
Ensembl chr 1:230,690,776...230,745,576 		JBrowse link
G AGTR1 angiotensin II receptor type 1 ISO mRNA:decreased expression:kidney: RGD PMID:7591011 RGD:10047107 NCBI chr 3:148,697,903...148,743,003
Ensembl chr 3:148,697,784...148,743,008 		JBrowse link
G CDKN1A cyclin dependent kinase inhibitor 1A ISO protein:decreased expression:vascular associated smooth muscle cell RGD PMID:17439406 RGD:2289672 NCBI chr 6:36,676,463...36,687,332
Ensembl chr 6:36,676,460...36,687,397 		JBrowse link
G CRP C-reactive protein ISO protein:increased expression:serum RGD PMID:22188107 RGD:6907405 NCBI chr 1:159,712,289...159,714,589
Ensembl chr 1:159,712,289...159,714,589 		JBrowse link
G CYP2C8 cytochrome P450 family 2 subfamily C member 8 IDA RGD PMID:20495177 RGD:7243143 NCBI chr10:95,036,772...95,069,497
Ensembl chr10:95,036,772...95,069,497 		JBrowse link
G CYP2J2 cytochrome P450 family 2 subfamily J member 2 ISO
IDA		 protein:increased expression:kidney RGD PMID:10779386 PMID:20495177 RGD:1625381, RGD:7243143 NCBI chr 1:59,893,308...59,969,212
Ensembl chr 1:59,893,308...59,926,773 		JBrowse link
G HMOX1 heme oxygenase 1 ISO RGD PMID:16316349 RGD:1582711 NCBI chr22:35,381,096...35,394,207
Ensembl chr22:35,380,361...35,394,214 		JBrowse link
G HSPA8 heat shock protein family A (Hsp70) member 8 IAGP DNA: snp: 5'utr: -110A>C Associated with chronic kidney disease RGD PMID:21475814 RGD:7242785 NCBI chr11:123,057,489...123,062,462
Ensembl chr11:123,057,489...123,063,230 		JBrowse link
G IL6 interleukin 6 ISO protein:increased expression:serum RGD PMID:22188107 RGD:6907405 NCBI chr 7:22,727,200...22,731,998
Ensembl chr 7:22,725,884...22,732,002 		JBrowse link
G MIR214 microRNA 214 ameliorates ISO RGD PMID:30049682 RGD:38500245 NCBI chr 1:172,138,798...172,138,907
Ensembl chr 1:172,138,798...172,138,907 		JBrowse link
G MMP2 matrix metallopeptidase 2 ISO RGD PMID:12923405 RGD:1302333 NCBI chr16:55,478,830...55,506,691
Ensembl chr16:55,389,700...55,506,691 		JBrowse link
G MMP7 matrix metallopeptidase 7 ISO protein:increased expression:kidney medulla RGD PMID:12923405 RGD:1302333 NCBI chr11:102,520,508...102,530,747
Ensembl chr11:102,520,508...102,530,750 		JBrowse link
G MMP9 matrix metallopeptidase 9 ISO RGD PMID:12923405 RGD:1302333 NCBI chr20:46,008,908...46,016,561
Ensembl chr20:46,008,908...46,016,561 		JBrowse link
G MT-ND1 mitochondrially encoded NADH:ubiquinone oxidoreductase core subunit 1 IAGP DNA:missense mutation RGD PMID:18194667 RGD:2300400 NCBI chr MT:3,307...4,262
Ensembl chr MT:3,307...4,262 		JBrowse link
G MYH9 myosin heavy chain 9 EXP CTD Direct Evidence: marker/mechanism CTD PMID:18794856 NCBI chr22:36,281,280...36,387,967
Ensembl chr22:36,281,280...36,388,010 		JBrowse link
G NOS2 nitric oxide synthase 2 ISO RGD PMID:20360752 RGD:4891374 NCBI chr17:27,756,766...27,800,529
Ensembl chr17:27,756,766...27,800,529 		JBrowse link
G NOS3 nitric oxide synthase 3 ISO RGD PMID:20938214 RGD:4891989 NCBI chr 7:150,991,017...151,014,588
Ensembl chr 7:150,991,017...151,014,588 		JBrowse link
G NPPA natriuretic peptide A ISO
EXP
IEP
IDA		 protein:increased expression:plasma:
CTD Direct Evidence: marker/mechanism
associated with Hypertension;protein:increased expression:plasma		 CTD
RGD		 PMID:8763405 PMID:20139323 PMID:12697975 PMID:15241786 RGD:7248593, RGD:7248660, RGD:7248617 NCBI chr 1:11,845,709...11,847,783
Ensembl chr 1:11,845,709...11,848,345 		JBrowse link
G NPPB natriuretic peptide B ISO
IEP		 protein:increased expression:serum
associated with Hypertension;protein:increased expression:plasma
protein:increased expression:plasma:		 RGD PMID:22188107 PMID:12697975 PMID:20139323 RGD:6907405, RGD:7248660, RGD:7248593 NCBI chr 1:11,857,464...11,858,945
Ensembl chr 1:11,857,464...11,858,945 		JBrowse link
G TIMP4 TIMP metallopeptidase inhibitor 4 ISO protein:increased expression:kidney medulla RGD PMID:12923405 RGD:1302333 NCBI chr 3:12,153,068...12,158,912
Ensembl chr 3:12,153,068...12,158,912 		JBrowse link
G TNF tumor necrosis factor ISO protein:increased expression:serum RGD PMID:22188107 RGD:6907405 NCBI chr 6:31,575,565...31,578,336
Ensembl chr 6:31,575,565...31,578,336 		JBrowse link
Renoprival Hypertension term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CAT catalase ISO RGD PMID:22733796 RGD:7206853 NCBI chr11:34,438,934...34,472,060
Ensembl chr11:34,438,934...34,472,060 		JBrowse link
renovascular hypertension term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACE angiotensin I converting enzyme treatment ISO RGD PMID:22342460 PMID:20630208 RGD:6893471, RGD:8157609 NCBI chr17:63,477,061...63,498,373
Ensembl chr17:63,477,061...63,498,380 		JBrowse link
G ADM adrenomedullin IEP protein:increased expression:plasma RGD PMID:15284680 RGD:1625303 NCBI chr11:10,305,073...10,307,397
Ensembl chr11:10,305,073...10,307,397 		JBrowse link
G ADRB1 adrenoceptor beta 1 ISO RGD PMID:17278011 PMID:15592645 RGD:7241568, RGD:7241580 NCBI chr10:114,043,866...114,046,904
Ensembl chr10:114,043,866...114,046,904 		JBrowse link
G AGTR1 angiotensin II receptor type 1 ISO mRNA:decreased expression:kidney: RGD PMID:21326341 PMID:9644212 PMID:16796846 RGD:5129177, RGD:10047119, RGD:5147455 NCBI chr 3:148,697,903...148,743,003
Ensembl chr 3:148,697,784...148,743,008 		JBrowse link
G AGTR2 angiotensin II receptor type 2 ISO RGD PMID:21189405 PMID:18158356 RGD:6903867, RGD:6903868 NCBI chr  X:116,170,744...116,174,974
Ensembl chr  X:116,170,744...116,174,974 		JBrowse link
G AVPR1A arginine vasopressin receptor 1A ISO mRNA:altered expression:brain RGD PMID:15613739 RGD:2300323 NCBI chr12:63,142,759...63,151,201
Ensembl chr12:63,142,759...63,151,201 		JBrowse link
G CAMK2D calcium/calmodulin dependent protein kinase II delta treatment ISO RGD PMID:26619200 RGD:401940196 NCBI chr 4:113,451,032...113,761,738
Ensembl chr 4:113,418,054...113,761,927 		JBrowse link
G CCND2 cyclin D2 ISO protein:increased expression:left ventricle: RGD PMID:26300251 RGD:151664604 NCBI chr12:4,273,762...4,305,353
Ensembl chr12:4,269,771...4,305,353 		JBrowse link
G CMA1 chymase 1 ISO protein:increased activity:kidney (rat) RGD PMID:15869764 RGD:1581745 NCBI chr14:24,505,353...24,508,265
Ensembl chr14:24,505,353...24,508,265 		JBrowse link
G CXCL10 C-X-C motif chemokine ligand 10 ISO RGD PMID:17062848 RGD:2311383 NCBI chr 4:76,021,118...76,023,497
Ensembl chr 4:76,021,118...76,023,497 		JBrowse link
G CXCR3 C-X-C motif chemokine receptor 3 ISO RGD PMID:17062848 RGD:2311383 NCBI chr  X:71,615,919...71,618,511
Ensembl chr  X:71,615,916...71,618,511 		JBrowse link
G DYRK1A dual specificity tyrosine phosphorylation regulated kinase 1A treatment ISO RGD PMID:26619200 RGD:401940196 NCBI chr21:37,365,573...37,526,358
Ensembl chr21:37,365,573...37,526,358 		JBrowse link
G EIF4G2 eukaryotic translation initiation factor 4 gamma 2 ISO mRNA:increased expression:heart left ventricle RGD PMID:12708758 RGD:10755511 NCBI chr11:10,797,046...10,808,926
Ensembl chr11:10,797,050...10,808,940 		JBrowse link
G FN1 fibronectin 1 ISO RGD PMID:17324142 RGD:7205461 NCBI chr 2:215,360,865...215,436,068
Ensembl chr 2:215,360,440...215,436,073 		JBrowse link
G G6PD glucose-6-phosphate dehydrogenase treatment ISO RGD PMID:22684021 RGD:10449172 NCBI chr  X:154,531,390...154,547,569
Ensembl chr  X:154,517,825...154,547,572 		JBrowse link
G GJA1 gap junction protein alpha 1 ISO RGD PMID:11422751 RGD:7207851 NCBI chr 6:121,435,646...121,449,727
Ensembl chr 6:121,435,595...121,449,727 		JBrowse link
G GJA5 gap junction protein alpha 5 ISO RGD PMID:11422751 RGD:7207851 NCBI chr 1:147,756,199...147,773,351
Ensembl chr 1:147,756,199...147,773,362 		JBrowse link
G HAVCR1 hepatitis A virus cellular receptor 1 IEP protein:increased expression:urine: RGD PMID:22923545 RGD:7245500 NCBI chr 5:157,029,413...157,069,407
Ensembl chr 5:157,026,742...157,069,396 		JBrowse link
G HDAC8 histone deacetylase 8 treatment ISO RGD PMID:27673327 RGD:13208809 NCBI chr  X:72,329,516...72,572,843
Ensembl chr  X:72,329,516...72,573,101 		JBrowse link
G LAMA2 laminin subunit alpha 2 ISO mRNA:decreased expression:heart RGD PMID:10773239 RGD:1600206 NCBI chr 6:128,883,138...129,516,566
Ensembl chr 6:128,883,138...129,516,566 		JBrowse link
G LCN2 lipocalin 2 IEP protein:increased expression:urine,plasma RGD PMID:22923545 RGD:7245500 NCBI chr 9:128,149,453...128,153,453
Ensembl chr 9:128,149,071...128,153,453 		JBrowse link
G MPO myeloperoxidase ISO protein:increased activity:heart, brain, kidney RGD PMID:19549002 RGD:7174698 NCBI chr17:58,269,855...58,280,935
Ensembl chr17:58,269,855...58,280,935 		JBrowse link
G NOS1 nitric oxide synthase 1 ISO RGD PMID:16788145 RGD:1642130 NCBI chr12:117,208,142...117,361,626
Ensembl chr12:117,208,142...117,452,170 		JBrowse link
G NOS3 nitric oxide synthase 3 EXP CTD Direct Evidence: therapeutic CTD PMID:18641695 NCBI chr 7:150,991,017...151,014,588
Ensembl chr 7:150,991,017...151,014,588 		JBrowse link
G PDGFA platelet derived growth factor subunit A ISO mRNA:increased expression:vascular associated smooth muscle cell RGD PMID:17439406 RGD:2289672 NCBI chr 7:497,258...520,700
Ensembl chr 7:497,258...520,296 		JBrowse link
G PRL prolactin ISO protein:increased expression:plasma RGD PMID:17316702 RGD:1642574 NCBI chr 6:22,287,246...22,302,835
Ensembl chr 6:22,287,244...22,302,826 		JBrowse link
G PTGER3 prostaglandin E receptor 3 ISO protein:increased expression:kidney (rat) RGD PMID:16788145 RGD:1642130 NCBI chr 1:70,852,358...71,047,816
Ensembl chr 1:70,852,353...71,047,816 		JBrowse link
G PTGS1 prostaglandin-endoperoxide synthase 1 ISO RGD PMID:17766473 RGD:2300258 NCBI chr 9:122,370,533...122,395,703
Ensembl chr 9:122,370,530...122,395,703 		JBrowse link
G RELA RELA proto-oncogene, NF-kB subunit ISO protein:increased expression:nucleus, kidney RGD PMID:18032469 RGD:2298840 NCBI chr11:65,653,601...65,663,857
Ensembl chr11:65,653,599...65,663,090 		JBrowse link
G REN renin ISO
IEP		 mRNA:increased expression:renal cortex (mouse)
protein:increased activity:blood plasma (human)		 RGD PMID:22378822 PMID:2240003 RGD:6892688, RGD:125097504 NCBI chr 1:204,154,819...204,166,337
Ensembl chr 1:204,154,819...204,190,324 		JBrowse link
G SLC9A1 solute carrier family 9 member A1 treatment ISO RGD PMID:12218313 RGD:727424 NCBI chr 1:27,098,809...27,155,125
Ensembl chr 1:27,098,809...27,166,981 		JBrowse link
G SLC9A3 solute carrier family 9 member A3 treatment ISO RGD PMID:12218313 RGD:727424 NCBI chr 5:470,456...524,449
Ensembl chr 5:470,456...524,449 		JBrowse link
G SPP1 secreted phosphoprotein 1 ISO RGD PMID:12620700 RGD:1581326 NCBI chr 4:87,975,714...87,983,411
Ensembl chr 4:87,975,667...87,983,532 		JBrowse link
G SRSF1 serine and arginine rich splicing factor 1 treatment ISO RGD PMID:26619200 RGD:401940196 NCBI chr17:57,989,038...58,007,246
Ensembl chr17:58,000,919...58,007,346 		JBrowse link
severe pre-eclampsia term browser
Symbol Object Name Qualifiers Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACVR1 activin A receptor type 1 severity IEP mRNA:increased expression:decidua basalis (human) RGD PMID:24331737 RGD:329845529 NCBI chr 2:157,736,446...157,876,330
Ensembl chr 2:157,736,251...157,876,330 		JBrowse link
G APEX1 apurinic/apyrimidinic endodeoxyribonuclease 1 susceptibility IAGP DNA:polymorphism::p.D148E (human) RGD PMID:24619222 RGD:401850778 NCBI chr14:20,455,226...20,457,767
Ensembl chr14:20,455,191...20,457,772 		JBrowse link
G COL4A2 collagen type IV alpha 2 chain severity IEP mRNA:increased expression:decidua basalis (human) RGD PMID:24331737 RGD:329845529 NCBI chr13:110,307,284...110,513,209
Ensembl chr13:110,305,812...110,513,209 		JBrowse link
G ERAP1 endoplasmic reticulum aminopeptidase 1 severity IEP mRNA:increased expression:decidua basalis (human) RGD PMID:24331737 RGD:329845529 NCBI chr 5:96,760,813...96,935,854
Ensembl chr 5:96,760,810...96,808,100 		JBrowse link
G ERAP2 endoplasmic reticulum aminopeptidase 2 severity IEP mRNA:increased expression:decidua basalis (human) RGD PMID:24331737 RGD:329845529 NCBI chr 5:96,875,939...96,919,716
Ensembl chr 5:96,875,986...96,919,703 		JBrowse link
G GPX3 glutathione peroxidase 3 IEP protein:increased expression:plasma RGD PMID:8476834 RGD:401827852 NCBI chr 5:151,020,591...151,028,988
Ensembl chr 5:151,020,591...151,028,988 		JBrowse link
G H19 H19 imprinted maternally expressed transcript severity IDA DNA:promoter:exon 1:hypermethylation RGD PMID:24969494 RGD:156430323 NCBI chr11:1,995,176...2,001,266
Ensembl chr11:1,995,165...2,004,552 		JBrowse link
G LNPEP leucyl and cystinyl aminopeptidase severity IEP mRNA:increased expression:decidua basalis (human) RGD PMID:24331737 RGD:329845529 NCBI chr 5:96,936,080...97,037,513
Ensembl chr 5:96,935,394...97,037,513 		JBrowse link
G MIR155 microRNA 155 severity IEP miRNA:increased expression:blood serum (human) RGD PMID:31487655 RGD:155582220 NCBI chr21:25,573,980...25,574,044
Ensembl chr21:25,573,980...25,574,044 		JBrowse link
G MIR210 microRNA 210 severity IEP miRNA:increased expression:blood serum (human)
miRNA:increased expression:blood plasma (human)		 RGD PMID:31487655 PMID:33778218 RGD:155582220, RGD:155582221 NCBI chr11:568,089...568,198
Ensembl chr11:568,089...568,198 		JBrowse link
G RBP4 retinol binding protein 4 severity IEP protein:decreased expression:blood serum (human)
protein:increased expression:blood serum (human)		 RGD PMID:31949674 PMID:27279411 PMID:19573524 RGD:329845847, RGD:329845859, RGD:329845853 NCBI chr10:93,591,694...93,601,744
Ensembl chr10:93,591,687...93,601,744 		JBrowse link
Term paths to the root
Path 1
Term Annotations click to browse term
  disease 97394
    disease of anatomical entity 91022
      cardiovascular system disease 16228
        vascular disease 12024
          artery disease 8205
            hypertension 1813
              Adams Nance Syndrome 0
              Diastolic Hypertension, Resistance to 2
              Faye-Petersen Ward Carey Syndrome 0
              Grange Syndrome 2
              Hypertension Resistant to Conventional Therapy 81
              Hypertension, Early-Onset, Autosomal Dominant, with Severe Exacerbation in Pregnancy 1
              Hypomagnesemia, Hypertension, and Hypercholesterolemia, Mitochondrial 1
              Idiopathic Intracranial Hypertension with Papilledema 0
              Isolated Systolic Hypertension 3
              Kallikrein Hypertension 0
              Masked Hypertension 1
              Pregnancy-Induced Hypertension + 292
              Rhizomelic Osteochondrodysplasia with Callosal Agenesis, Thrombocytopenia, Hydrocephalus, and Hypertension 0
              Stress-Induced Hypertension 0
              Tachycardia, Hypertension, Microphthalmia, And Hyperglycinuria 0
              White Coat Hypertension 0
              early onset hypertension 1
              essential hypertension + 51
              hypertension and brachydactyly syndrome 3
              hypertensive retinopathy 2
              malignant hypertension + 4
              pulmonary hypertension + 431
              secondary hypertension + 78
paths to the root