NQO1 (NAD(P)H quinone dehydrogenase 1) - Rat Genome Database

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Gene: NQO1 (NAD(P)H quinone dehydrogenase 1) Homo sapiens
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Symbol: NQO1
Name: NAD(P)H quinone dehydrogenase 1
RGD ID: 735868
HGNC Page HGNC:2874
Description: Enables NADH:ubiquinone reductase (non-electrogenic) activity and identical protein binding activity. Involved in several processes, including cell redox homeostasis; negative regulation of ferroptosis; and removal of superoxide radicals. Located in cytosol. Implicated in several diseases, including hematologic cancer (multiple); hypertension; lung disease (multiple); macular degeneration; and small cell carcinoma. Biomarker of alcoholic hepatitis; breast cancer; chronic obstructive pulmonary disease; and pulmonary emphysema.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: azoreductase; DHQU; DIA4; diaphorase (NADH/NADPH) (cytochrome b-5 reductase); diaphorase-4; dioxin-inducible 1; DT-diaphorase; DTD; menadione reductase; NAD(P)H dehydrogenase [quinone] 1; NAD(P)H dehydrogenase, quinone 1; NAD(P)H-quinone oxidoreductase; NAD(P)H:menadione oxidoreductase 1; NAD(P)H:Quinone acceptor oxidoreductase type 1; NAD(P)H:quinone oxidoreductase 1; NAD(P)H:quinone oxireductase; NMOR1; NMORI; phylloquinone reductase; QR1; quinone reductase 1
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381669,709,401 - 69,726,560 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1669,706,996 - 69,726,668 (-)EnsemblGRCh38hg38GRCh38
GRCh371669,743,304 - 69,760,463 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361668,300,805 - 68,318,034 (-)NCBINCBI36Build 36hg18NCBI36
Build 341668,300,809 - 68,317,893NCBI
Celera1654,257,766 - 54,274,991 (-)NCBICelera
Cytogenetic Map16q22.1NCBI
HuRef1655,621,397 - 55,638,606 (-)NCBIHuRef
CHM1_11671,151,192 - 71,168,417 (-)NCBICHM1_1
T2T-CHM13v2.01675,511,583 - 75,528,719 (-)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model